CN110124139B - Device and method for recycling residual blood during ECMO machine withdrawal - Google Patents

Device and method for recycling residual blood during ECMO machine withdrawal Download PDF

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Publication number
CN110124139B
CN110124139B CN201910387734.2A CN201910387734A CN110124139B CN 110124139 B CN110124139 B CN 110124139B CN 201910387734 A CN201910387734 A CN 201910387734A CN 110124139 B CN110124139 B CN 110124139B
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ecmo
blood
way valve
pipeline
physiological saline
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CN110124139A (en
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鲁玉凤
邱芳
董东伟
刘子由
郭林
郭兰
王凤珍
陈洪
段志胜
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First Affiliated Hospital of Gannan Medical University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3643Priming, rinsing before or after use
    • A61M1/3644Mode of operation
    • A61M1/3646Expelling the residual body fluid after use, e.g. back to the body

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)

Abstract

The invention relates to the technical field of medical treatment, in particular to a device and a method for recovering residual blood when an ECMO patient is withdrawn, wherein the device comprises an ECMO machine, a VV-ECMO or VA-ECMO cannula, an ECMO pipeline, a blood preservation liquid bag and 0.9% physiological saline, the blood preservation liquid bag can contain recovered blood, and 0.9% physiological saline washes the blood in the ECMO pipeline into the blood preservation liquid bag. On the basis of strict sterile operation during machine withdrawal, the VV-ECMO/VA-ECMO cannula is cut off and connected through a sterile connecting pipe, a three-way valve is respectively connected to two interfaces in front of the centrifugal pump, the three-way valve at the proximal end of the centrifugal pump is connected with 0.9% physiological saline, the three-way valve at the distal end of the centrifugal pump is connected with a blood preservation liquid bag to form a closed loop, and the ECMO machine is started to collect residual blood. The invention can timely recycle about 500-600 ml of residual blood in the ECMO pipeline, and the recycled blood treated by the transfusion department can be returned to the patient.

Description

Device and method for recycling residual blood during ECMO machine withdrawal
Technical Field
The invention relates to the technical field of medical treatment, in particular to a device and a method for recycling residual blood during ECMO machine withdrawal.
Background
With the great development of surgical operations and the incapability of continuing to utilize a great deal of blood loss in the surgical process, the clinical blood demand is increased increasingly, and the blood source is stressed. In the prior art, after the extracorporeal circulation of the heart operation is finished, the machine residual blood is generally recovered after the steel wire is penetrated after the surgical hemostasis is finished, but the interval time from the end of the extracorporeal circulation to the completion of the steel wire is long, the machine residual blood is always remained in a pipeline to prevent the possibility of rotating the machine, although the effect of standby at any time is effectively achieved, but during the chest-related hemostasis, the machine residual blood cannot be returned to a patient, and the proper blood volume is maintained by the infusion of crystal body fluid and colloid liquid instead, the condition causes the reduction of the hemoglobin of the patient, so that when the hemoglobin of the patient is low to a certain extent, allogenic red blood cells are required to be infused, simultaneously, the haemostasis difficulty is increased due to the fact that the relatively low hemoglobin of the patient is unfavorable for hemostasis, the haemostasis time is also increased, the pericardial mediastinal drainage amount is increased in the chest-related hemostasis and steel wire penetrating process and after the ICU is returned, when the relatively large drainage amount is contained in the recovered machine residual blood, the chest-related hemostasis is not carried out in the process and the machine residual blood is returned to the ICU, the blood is not contained in the machine residual blood is polluted, and the blood is not polluted by the machine residual blood is polluted when the blood is recovered, and the blood is not completely is recovered, and the blood is polluted when the medical staff is exposed to the blood is polluted, and the blood is not is completely and the machine is completely is recovered, and the blood is not is polluted.
Disclosure of Invention
The invention aims to solve the problems that in the prior art, an ECMO pipeline Yu Xiezhi is left in a pipeline, and residual blood in the pipeline is not timely recovered to cause blood waste or part of blood is exposed to air in the blood recovery process and cannot be thoroughly recovered, and provides a residual blood recovery device and a method for ECMO machine withdrawal.
In order to achieve the above object, the present invention provides a device for recovering residual blood during ECMO withdrawal, wherein the device for recovering residual blood during ECMO withdrawal needs to drive the whole device by placing a centrifugal pump into the ECMO withdrawal, and the device for recovering residual blood during ECMO withdrawal comprises:
the ECMO device comprises an ECMO machine, a VV-ECMO/VA-ECMO cannula, a centrifugal pump, a membrane lung, an ECMO pipeline at the outlet end of the membrane lung, an ECMO pipeline at the inlet end of the centrifugal pump, and a first interface and a second interface on the ECMO pipeline at the inlet end of the centrifugal pump;
The three-way valve is connected to the first interface and the second interface, and the three-way valve connected to the second interface is connected with a heparin cap;
The sterile connecting pipe is used for connecting an ECMO pipeline at the outlet end of the membrane lung with an ECMO pipeline at the inlet end of the centrifugal pump after cutting off the VV-ECMO/VA-ECMO cannula of the ECMO device;
a blood preservation liquid bag connected with the heparin cap on the three-way valve, wherein the blood preservation liquid bag is used for containing the recovered blood;
The physiological saline bag is connected with the three-way valve on the first connector and is used for providing physiological saline and flushing residual blood in the ECMO device into the blood preservation liquid bag for collection;
the first vascular clamp is arranged on the ECMO pipeline between the first interface and the second interface and is used for clamping the pipeline, and residual blood cannot flow back to the physiological saline bag end after the centrifugal pump is started and only enters the blood preservation liquid bag;
And the second vascular clamp is arranged on the ECMO pipeline from the outlet end of the centrifugal pump to the inlet end of the membrane lung, and is clamped when the ECMO machine stops rotating/is started, so that the backflow of blood is prevented.
Preferably, the lower end of the physiological saline bag is connected with an ECMO pre-flushing connecting pipe, the upper end of the ECMO pre-flushing connecting pipe is connected with the physiological saline bag, and the lower end of the ECMO pre-flushing connecting pipe is connected with a three-way valve.
Preferably, the upper end of the ECMO pre-flushing connecting pipe is provided with a tip connector, the tip connector at the upper end can be directly inserted into a physiological saline bag, and the lower end of the ECMO pre-flushing connecting pipe is provided with a threaded connector which can be directly connected to a three-way valve of the first connector to realize quick connection.
Preferably, the blood preservation liquid bag is provided with a connecting pipe, the tail end of the connecting pipe is provided with a needle, and the needle can be directly inserted into a heparin cap of the three-way valve to realize quick connection.
Preferably, connectors are arranged at two ends of the sterile connecting pipe, and the ECMO pipeline at the outlet end of the membrane lung and the ECMO pipeline at the inlet end of the centrifugal pump are connected with the connectors at two ends of the sterile connecting pipe in an inserting mode.
Preferably, the number of the physiological saline bags is two bottles of 500ml of 0.9% physiological saline.
The method for recycling the residual blood by using the residual blood recycling device during the ECMO machine removal comprises the following steps:
S1, stopping an ECMO, cutting off a VV-ECMO/VA-ECMO cannula under the operation of strict aseptic operation, and connecting the VV-ECMO/VA-ECMO cannula through an aseptic connecting pipe to form a closed loop;
S2, always clamping the first pipe tongs to ensure that blood in the closed pipeline does not circulate; the second vascular clamp is clamped when the ECMO machine is stopped/started, so that the blood is guaranteed not to flow reversely, the three-way valve is quickly connected to the first connector, the three-way valve is connected to the second connector, and the three-way valve on the second connector is connected with the heparin cap;
S3, inserting a tip connector at the upper end of the ECMO pre-flushing connecting pipe into a 0.9% physiological saline bag, connecting a threaded connector at the lower end of the ECMO pre-flushing connecting pipe to a three-way valve of a first connector, opening a valve of the three-way valve after connecting, discharging air in a pipeline of the ECMO pre-flushing connecting pipe by utilizing gravity, and closing the valve of the position of the three-way valve;
S4, directly inserting a needle at the tail end of a connecting pipe of the blood preservation liquid bag into a heparin cap of the three-way valve;
s5, after the flow and rotation speed measurement is subjected to return-to-0 calibration, the ECMO rotation number is increased to 1500 rotations, the second vascular clamp is opened, the rotation number is gradually increased to not more than 2000 rotations, the physiological saline consumption of the physiological saline bag is observed, and the physiological saline bag is replaced in time;
s6, continuously gently shaking the blood preservation liquid bag until the blood in the ECMO pipeline is completely recovered;
S7, stopping, evacuating all objects and returning.
Through the technical scheme, the device can timely recover residual blood in the ECMO pipeline when a patient is removed, and can be returned to the patient after being treated by a hematology department, so that blood resources are fully utilized, blood waste is avoided, the device is a closed blood recovery system, the problem of blood pollution is avoided, and the recovery is safer and more thorough; the recovered blood is effectively treated and then is returned to the patient, so that the problem that the hemoglobin amount is reduced due to the infusion of the crystal body fluid and the colloid liquid after the operation of the patient is solved, the requirement on allogenic blood is reduced, and the recovery and the subsequent treatment of the patient are facilitated.
Drawings
FIG. 1 is a schematic diagram of a device for recovering residual blood during ECMO machine withdrawal according to the present invention;
fig. 2 is a schematic view of a sterile connection tube of the residual blood recovery device in the ECMO withdrawal machine according to the present invention.
Reference numerals
1-Centrifugal pump, 2-membranous lung, 3-ECMO pipeline, 4-ECMO pipeline, 41-interface I, 411-three-way valve, 42-interface II, 421-three-way valve, 422-heparin cap, 43-first vascular clamp, 44-second vascular clamp, 5-physiological saline bag, 51-ECMO pre-flushing connecting pipe, 6-blood preservation liquid bag, 61-connecting pipe and 7-sterile connecting pipe.
Detailed Description
The present invention will now be described in detail with reference to the drawings and the detailed description, it being understood that the detailed description described herein is for illustration and explanation only and is not intended to limit the invention.
According to the invention, when the ECMO machine is removed, the centrifugal pump 1 is put into the ECMO machine to drive the whole ECMO device, and when the ECMO machine is removed, the ECMO pipeline is connected into a closed pipeline under strict sterile operation, so that no blood is exposed to the air, the safety is improved, and the recovery is more thorough.
Referring to fig. 1 and 2, the ECMO device for recovering the residual blood during the removal of the ECMO machine includes a whole ECMO device, where the ECMO device includes an ECMO machine, a VV-ECMO/VA-ECMO cannula, a centrifugal pump 1, a membrane lung 2, an ECMO pipeline 3 at an outlet end of the membrane lung 2, an ECMO pipeline 4 at an inlet end of the centrifugal pump 1, and a first interface 41 and a second interface 42 on the ECMO pipeline 4 at an inlet end of the centrifugal pump 1; the first interface 41 and the second interface 42 are provided with connectable threads.
The first interface 41 is connected with a three-way valve 411 in a threaded manner, the second interface 42 is connected with a three-way valve 421 in a threaded manner, and the three-way valve 421 is connected with a heparin cap 422 in a threaded manner;
The sterile connecting pipe 7 is used for connecting the ECMO pipeline 3 at the outlet end of the membrane lung 2 with the ECMO pipeline 4 at the inlet end of the centrifugal pump 1 after cutting off the VV-ECMO/VA-ECMO cannula of the ECMO device; the two ends of the sterile connecting pipe 7 are provided with connectors, and the ECMO pipeline 3 at the outlet end of the membrane lung 2 and the ECMO pipeline 4 at the inlet end of the centrifugal pump 1 can be spliced with the connectors at the two ends of the sterile connecting pipe 7.
The blood preservation liquid bag 6 is connected with the heparin cap 422 on the three-way valve 421, the blood preservation liquid bag 6 is used for containing the recovered blood, the blood preservation liquid bag 6 is provided with a connecting pipe 61, the tail end of the connecting pipe 61 is provided with a needle, and the needle can be directly inserted into the heparin cap 422 of the three-way valve 421 to realize quick connection.
The physiological saline bag 5 is connected with the three-way valve 411, the physiological saline bag 5 is used for providing physiological saline, residual blood in the ECMO device is flushed into the blood preservation liquid bag 6 to be collected, the lower end of the physiological saline bag 5 is connected with the ECMO pre-flushing connecting pipe 51, the upper end of the ECMO pre-flushing connecting pipe 51 is provided with a tip connector, the tip connector at the upper end can be directly connected with the physiological saline bag 5 in an inserting mode, and the lower end of the ECMO pre-flushing connecting pipe is provided with a threaded connector which can be directly connected to the three-way valve 411 to realize quick connection.
The first vascular clamp 43 is arranged on the ECMO pipeline 4 between the first interface 41 and the second interface 42, the first vascular clamp 43 is used for clamping the pipeline, residual blood cannot flow back to the end of the physiological saline bag 5 after the centrifugal pump 1 is started, and the residual blood can only enter the blood preservation liquid bag 6, so that the smooth collection of the residual blood is ensured;
and a second vascular clamp 44 arranged on the ECMO pipeline from the outlet end of the centrifugal pump 1 to the inlet end of the membrane lung 2 and used for clamping when the ECMO machine stops/starts, wherein the second vascular clamp 44 clamps the ECMO pipeline to prevent blood from flowing backwards.
In a preferred embodiment of the invention, the number of the physiological saline bags 5 is two bottles of 500ml of 0.9% physiological saline, the physiological saline bags 5 which are about to be used up need to be replaced in time in the recovery process, and the replacement is fast and skillful, so that the influence of air entering a pipeline on the blood recovery amount is avoided.
The invention also provides a method for recovering residual blood by using the residual blood recovery device when the ECMO patient is removed, which comprises the following steps:
s1, stopping the ECMO, cutting off a VV-ECMO/VA-ECMO cannula under the operation of strict aseptic operation, and connecting the VV-ECMO/VA-ECMO cannula through an aseptic connecting pipe 7 to form a closed loop;
S2, always clamping the first pipe tongs 43 to ensure that blood in the closed pipeline does not circulate; the second vascular clamp 44 is clamped when the ECMO machine is stopped/started, so that the blood is guaranteed not to flow reversely, the three-way valve 411 is quickly connected to the first interface 41, the three-way valve 421 is connected to the second interface 42, and the three-way valve 421 is connected with the heparin cap 422;
S3, a tip connector at the upper end of the ECMO pre-flushing connecting pipe 51 is inserted into 0.9% of physiological saline bag 5, a threaded connector at the lower end of the ECMO pre-flushing connecting pipe is connected to a three-way valve 411, a one-way valve of the three-way valve 411 is opened after connection, and after air in a pipeline of the ECMO pre-flushing connecting pipe 51 is discharged by utilizing gravity, the one-way valve of the three-way valve 411 is closed;
s4, directly inserting a needle at the tail end of the connecting pipe 61 of the blood preservation liquid bag 6 into the heparin cap 422 of the three-way valve 421;
S5, after the flow and rotation speed measurement is subjected to return-to-0 calibration, the ECMO rotation number is increased to 1500 rotations, the second vascular clamp 44 is opened, the rotation number is gradually increased to no more than 2000 rotations, the physiological saline consumption of the physiological saline bag 5 of 0.9% is observed, and the physiological saline bag is replaced in time;
S6, continuously gently shaking the blood preservation liquid bag 6 until the blood in the ECMO pipeline is completely recovered;
S7, stopping, evacuating all objects and returning.
In step S3, the air in the pipeline of the ECMO pre-flushing connection pipe 51 is exhausted by gravity, and then the ECMO pre-flushing connection pipe 51 is inserted into the three-way valve 411, so that the air is prevented from entering the pipeline to cause the stop of the centrifugal pump 1, and the blood recovery effect is prevented from being affected.
After the centrifugal pump 1 of the ECMO machine is started to operate, 0.9% of normal saline water bag 5,0.9% of normal saline water flows through the ECMO pre-flushing connecting pipe 51, the centrifugal pump 1, the membrane lung 2 and the ECMO pipeline 3, and finally flows into the blood preservation liquid bag 6.
Further, the number of the physiological saline bags 5 in the step S5 is two bottles of 500ml of 0.9% physiological saline; in the residual blood recovery operation process, when the physiological saline water in the physiological saline water bag 5 is about to be insufficient, the three-way valve 411 at the position is closed, the three-way valve 411 is opened after the physiological saline water bag 5 is quickly and timely replaced, and the phenomenon that the centrifugal pump 1 stops rotating and the blood recovery effect is influenced due to the fact that air enters a pipeline is avoided.
Further, after blood collection, because the blood in the blood preservation solution bag 6 has excessive brine, in order to avoid the circulation overload during the blood reinfusion, the recovered blood is stored in a blood preservation refrigerator at the temperature of 2-6 ℃ for 12-24 hours, after red blood cells settle, the supernatant plasma and the brine are discharged into an empty bag through a combined bag, and the red blood cell bag is reinfusion into a patient after being preheated, so that the hemoglobin content of the patient is increased, and the recovery of the patient is facilitated.
By using the recovery device provided by the invention, the residual blood in the ECMO machine can be effectively and thoroughly recovered, the blood resource is saved, the residual blood can be returned to a patient after being treated by a hematology department, the hemoglobin content of the patient is improved, and the demand for allogeneic blood is reduced.
The basic principle, the operation method and the advantages of the present invention have been described in detail above, but the present invention is not limited thereto, and various equivalent modifications and modifications can be made to the technical solution of the present invention within the scope of the technical concept of the present invention, including the combination of the respective technical features in any other suitable manner, and these simple modifications and combinations should also be regarded as being included in the scope of the present invention.

Claims (5)

1. An ECMO withdrawal waste blood recovery device comprising:
the ECMO device comprises an ECMO machine, a VV-ECMO/VA-ECMO cannula, a centrifugal pump, a membrane lung, an ECMO pipeline at the outlet end of the membrane lung, an ECMO pipeline at the inlet end of the centrifugal pump, and a first interface and a second interface on the ECMO pipeline at the inlet end of the centrifugal pump;
The three-way valve is connected to the first interface and the second interface, and the three-way valve connected to the second interface is connected with a heparin cap;
The sterile connecting pipe is used for connecting an ECMO pipeline at the outlet end of the membrane lung with an ECMO pipeline at the inlet end of the centrifugal pump after cutting off the VV-ECMO/VA-ECMO cannula of the ECMO device;
a blood preservation liquid bag connected with the heparin cap on the three-way valve, wherein the blood preservation liquid bag is used for containing the recovered blood; the blood preservation liquid bag is provided with a connecting pipe, the tail end of the connecting pipe is provided with a needle head, and the needle head can be directly inserted into a heparin cap of the three-way valve to realize quick connection;
The physiological saline bag is connected with the three-way valve on the first connector and is used for providing physiological saline and flushing residual blood in the ECMO device into the blood preservation liquid bag for collection; the lower end of the physiological saline bag is connected with an ECMO pre-flushing connecting pipe, the upper end of the ECMO pre-flushing connecting pipe is connected with the physiological saline bag, and the lower end of the ECMO pre-flushing connecting pipe is connected with a three-way valve of a first connector;
the first vascular clamp is arranged on the ECMO pipeline between the first interface and the second interface and is used for clamping the pipeline, and residual blood cannot flow back to the physiological saline bag end after the centrifugal pump is started and only enters the blood preservation liquid bag;
And the second vascular clamp is arranged on the ECMO pipeline from the outlet end of the centrifugal pump to the inlet end of the membrane lung, and is clamped when the ECMO machine stops rotating/is started, so that the backflow of blood is prevented.
2. The device for recovering residual blood during ECMO machine withdrawal according to claim 1, wherein a tip connector is arranged at the upper end of the ECMO pre-flushing connecting pipe, the tip connector at the upper end can be directly inserted into a physiological saline bag, and a threaded connector is arranged at the lower end of the ECMO pre-flushing connecting pipe, so that the ECMO pre-flushing connecting pipe can be directly connected to a three-way valve of the first connector to realize quick connection.
3. The ECMO pump removal residual blood recovery apparatus according to claim 1, wherein connectors are provided at both ends of the sterile connection pipe, and the ECMO pipe at the exit end of the membrane lung is connected with the ECMO pipe at the entrance end of the centrifugal pump by plugging the connectors at both ends of the sterile connection pipe.
4. The ECMO pump-down residual blood recovery apparatus according to claim 1, wherein the number of the physiological saline bags is two bottles of 500ml of 0.9% physiological saline.
5. A method for recovering waste blood by using the ECMO machine according to any one of claims 1 to 4, comprising the steps of:
S1, stopping an ECMO, cutting off a VV-ECMO/VA-ECMO cannula under the operation of strict aseptic operation, and connecting the VV-ECMO/VA-ECMO cannula through an aseptic connecting pipe to form a closed loop;
S2, always clamping the first pipe tongs to ensure that blood in the closed pipeline does not circulate; the second vascular clamp is clamped when the ECMO machine is stopped/started, so that the blood is guaranteed not to flow reversely, the three-way valve is quickly connected to the first connector, the three-way valve is connected to the second connector, and the three-way valve on the second connector is connected with the heparin cap;
S3, inserting a tip connector at the upper end of the ECMO pre-flushing connecting pipe into a 0.9% physiological saline bag, connecting a threaded connector at the lower end of the ECMO pre-flushing connecting pipe to a three-way valve of a first connector, opening a valve of the three-way valve after connecting, discharging air in a pipeline of the ECMO pre-flushing connecting pipe by utilizing gravity, and closing the valve of the position of the three-way valve;
S4, directly inserting a needle at the tail end of a connecting pipe of the blood preservation liquid bag into a heparin cap of the three-way valve;
S5, after the flow and rotation speed measurement is subjected to return-to-0 calibration, the ECMO rotation number is increased to 1500 rotations, the second vascular clamp is opened, the rotation number is gradually increased to not more than 2000 rotations, the physiological saline consumption of the physiological saline bag is observed, and the physiological saline bag is replaced in time;
s6, continuously gently shaking the blood preservation liquid bag until the blood in the ECMO pipeline is completely recovered;
S7, stopping, evacuating all objects and returning.
CN201910387734.2A 2019-05-10 2019-05-10 Device and method for recycling residual blood during ECMO machine withdrawal Active CN110124139B (en)

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