CN110090328B

CN110090328B - Peritoneal dialysis catheter

Info

Publication number: CN110090328B
Application number: CN201910531576.3A
Authority: CN
Inventors: 张磊; 刘虹; 刘映红
Original assignee: Individual
Current assignee: Second Xiangya Hospital of Central South University
Priority date: 2019-06-19
Filing date: 2019-06-19
Publication date: 2021-11-26
Anticipated expiration: 2039-06-19
Also published as: CN110090328A

Abstract

The utility model provides a peritoneal dialysis catheter, including the pipe body, glucose monitoring probe and bar liquid bag, the one end of pipe body is the dialysis district, a plurality of dialysis holes have been seted up on the dialysis district, outside dialysis liquid bag is connected to the other end, the one end and the glucose monitoring probe connection that dialysis hole was seted up to the pipe body, bar liquid bag is located in the inner chamber of pipe body, and length is not less than the length of dialysis district on the pipe body, the one end of bar liquid bag is equipped with annotates the liquid mouth, annotate the one end that this body coupling of pipe outside dialysis liquid bag was located to the liquid mouth, the opening part of annotating the liquid mouth is equipped with the rubber buffer. The invention has the advantages that the peritoneal dialysis catheter does not float, has good sealing performance and no blockage of dialysis holes, and can monitor the glucose concentration of the dialysate in the peritoneal cavity in real time.

Description

Peritoneal dialysis catheter

Technical Field

The invention relates to the field of medical instruments, in particular to a peritoneal dialysis catheter.

Background

Dialysis is a separation and purification technique for separating small molecules from biological macromolecules by the principle that small molecules diffuse into water (or buffer solution) through a semipermeable membrane, and dialysis therapy is a treatment method for discharging components (solute or moisture) in body fluid to the outside of the body through a semipermeable membrane, and is generally divided into hemodialysis and peritoneal dialysis. Peritoneal dialysis is a variant of artificial blood purification, the peritoneum with good blood supply of a patient is used as a semipermeable membrane of the body, prepared dialysate is infused into the peritoneal cavity of the patient through a catheter by utilizing the action of gravity, so that the solute on one side with high concentration can move to one side with low concentration (diffusion effect) due to the concentration gradient difference of the solute on the two sides of the peritoneum, moisture can move from one side with low concentration to one side with high concentration (osmosis effect), and the dialysate in the peritoneal cavity is continuously replaced so as to achieve the purposes of removing in-vivo metabolites and toxic substances and correcting water and electrolyte balance disorder.

Peritoneal dialysis has the advantages of better residual renal function protection, good social compliance, convenience for patients and the like, is one of effective methods for renal function replacement treatment of patients with renal failure (uremia) confirmed by the medical community, and factors influencing peritoneal dialysis comprise: a concentration gradient of a solute; dialysate volume and flow rate; the effective area of the peritoneum; peritoneal dialysis fluid residence time; glucose concentration in the dialysate; the temperature of the dialysate.

The existing peritoneal dialysis catheter usually adopts a straight tube type dialysis catheter, and in the dialysis process, the peritoneal dialysis catheter needs to be kept in place for a long time so as to communicate the inside and outside of an abdominal cavity for liquid exchange. However, the straight tube dialysis tube has the problems of easy tube floating, poor sealing property, easy blockage and the like, the dialysis efficiency is affected, and even serious consequences such as bacterial infection and the like can be caused; in addition, the glucose concentration of the dialysate in the peritoneal cavity cannot be monitored in real time, and the optimal effect of peritoneal dialysis cannot be guaranteed.

Disclosure of Invention

The invention aims to solve the technical problem of overcoming the defects in the prior art and providing the peritoneal dialysis catheter which has no floating tube, good sealing performance and can monitor the glucose concentration of the dialysate in the peritoneal cavity in real time.

The technical scheme adopted by the invention for solving the technical problem is that the peritoneal dialysis catheter comprises a catheter body, a glucose monitoring probe and a strip-shaped liquid bag, wherein one end of the catheter body is a dialysis area, a plurality of dialysis holes are formed in the dialysis area, the other end of the catheter body is connected with an external dialysis liquid bag, one end of the catheter body, provided with the dialysis holes, is connected with the glucose monitoring probe, the strip-shaped liquid bag is arranged in an inner cavity of the catheter body and is not smaller than the dialysis area on the catheter body, one end of the strip-shaped liquid bag is provided with a liquid injection port, the liquid injection port is arranged at one end of the catheter body, connected with the external dialysis liquid bag, and a rubber plug is arranged at an opening of the liquid injection port.

Preferably, glucose monitor probe includes sealed casing, glucose probe, data acquisition module, wireless transmission module, miniature battery and FPC flexbile, in sealed casing's accommodation space was all located to data acquisition module, wireless transmission module and FPC circuit board, data acquisition module, glucose probe, wireless transmission module and miniature battery pass through FPC flexbile electric connection, the one end and the FPC flexbile connection of glucose probe, the other end stretches out sealed casing.

Preferably, the micro battery is arranged on the outer wall of one end, close to the liquid injection port, of the catheter body, the micro battery is connected with the FPC flexible board through a conducting wire, and the conducting wire is arranged in the inner cavity of the catheter body.

Preferably, the inner side wall of the catheter body is provided with a connecting part extending along the axial direction, the outer side wall of the strip-shaped liquid bag is connected with the inner side wall of the catheter body through the connecting part, and the conducting wire is arranged in the connecting part.

Preferably, the sealing shell is provided with a first through hole, and the first through hole is communicated with the conduit body.

Preferably, the glucose probe is a platinum electrode with glucose oxidase, and the surface of the platinum electrode is a semi-permeable membrane.

Preferably, one end of the glucose monitoring probe is provided with a spherical support frame, the spherical support frame is provided with a plurality of second through holes, and the glucose probe is arranged in a cavity of the spherical support frame.

Preferably, the spherical support frame is a corrosion-resistant metal.

Preferably, the X-ray developing contrast agent is added into the liquid injected by the strip-shaped liquid bag.

Preferably, the material of the strip-shaped liquid bag is nylon elastomer Pebax or natural latex.

Compared with the prior art, the invention has the beneficial effects that:

1. when the dialysis is not carried out, the rubber plug is pierced by using the injector, liquid is injected into the strip-shaped liquid bag through the liquid injection port, the strip-shaped liquid bag expands after being filled with the liquid, and a dialysis hole can be sealed from the inside of the catheter body, so that tissues in peritoneal cavities such as omentum majus and the like can be prevented from blocking the dialysis hole, the peritoneal cavity can be isolated from the outside, the risk of infection or leakage is reduced, meanwhile, an X-ray developing contrast medium is added into the injection liquid of the strip-shaped liquid bag, the dialysis area of the peritoneal dialysis tube can be developed under an X-ray film, and the position of the dialysis area can be conveniently observed;

2. during dialysis, the titanium alloy joint is connected with an external connecting pipe of the peritoneal dialysis bag, the rubber plug is pierced by using the syringe, the strip-shaped liquid bag is pumped out through the liquid injection port to inject liquid, the strip-shaped liquid bag contracts, the peritoneal dialysis liquid is dialyzed through the dialysis hole, the corrosion-resistant metal spherical support frame prevents a glucose probe from being directly contacted with tissues in the peritoneal cavity, the glucose probe monitors the glucose concentration in the peritoneal dialysis liquid in real time, and the monitored data is sent to the mobile terminal through the wireless transmission module, so that a doctor can master the glucose concentration of the dialysis liquid in the peritoneal cavity in real time, problems can be timely found and solved, and convenience and rapidness are realized;

3. the glucose monitoring probe with a certain weight sinks downwards due to gravity, so that the dialysis area reaches the lower part of the peritoneal cavity to prevent tube floating;

4. the miniature battery is externally arranged at one end of the catheter body connected with the dialysate bag, so that the battery can be conveniently and quickly replaced, and the dialysis catheter can normally work for a long time.

Drawings

The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the invention without limiting the invention.

FIG. 1 is a schematic structural diagram of an embodiment of the present invention;

FIG. 2 is a schematic diagram of the glucose monitoring probe of FIG. 1;

fig. 3 is a cross-sectional view of the embodiment shown in fig. 1.

Description of reference numerals: 1-catheter body, 10-dialysis area, 11-dialysis hole, 13-connecting part; 2-glucose monitoring probe, 21-sealed shell, 211-first through hole, 22-glucose probe, 23-data acquisition module, 24-wireless transmission module, 25-micro battery, 251-lead, 26-FPC flexible plate, 27-spherical support frame, 271-second through hole; 3-strip liquid bag, 31-liquid injection port and 311-rubber plug.

Detailed Description

The technical scheme provided by the embodiment of the invention is described in detail below with reference to the accompanying drawings.

Please refer to fig. 1-3, this embodiment includes the catheter body 1, the glucose monitoring probe 2 and the strip-shaped liquid bag 3, one end of the catheter body 1 is the dialysis area 10, a plurality of dialysis holes 11 are opened on the dialysis area 10, the other end is connected with the external dialysate bag, one end of the catheter body 1 opened with the dialysis holes 11 is connected with the glucose monitoring probe 2, the strip-shaped liquid bag 3 is arranged in the inner cavity of the catheter body 1, and the length is not less than the length of the dialysis area 10 on the catheter body 1, one end of the strip-shaped liquid bag 3 is provided with the liquid injection port 31, the liquid injection port 31 is arranged at one end of the catheter body 1 connected with the external dialysate bag, and the opening of the liquid injection port 31 is provided with the rubber plug 311.

The glucose monitoring probe 2 comprises a sealing shell 21, a glucose probe 22, a data acquisition module 23, a wireless transmission module 24, a micro battery 25 and an FPC flexible board 26, wherein the data acquisition module 23, the wireless transmission module 24 and the FPC circuit board 26 are all arranged in an accommodating space of the sealing shell 21, the data acquisition module 23, the glucose probe 22, the wireless transmission module 24 and the micro battery 25 are electrically connected through the FPC flexible board 26, one end of the glucose probe 22 is connected with the FPC flexible board 26, the other end of the glucose probe extends out of the sealing shell 21 to detect the glucose concentration of dialysate in a peritoneal cavity, the data acquisition module 23 is respectively electrically connected with the glucose probe 22, the wireless transmission module 24 and the micro battery 25, the wireless transmission module 24 transmits monitored data to a mobile terminal through Bluetooth communication, a doctor is facilitated to master the concentration of the peritoneal dialysate in real time, and problems are timely discovered and solved, is convenient and quick.

Miniature battery 25 locates on the outer wall that catheter body 1 is close to annotate liquid mouth 31 one end, and miniature battery 25 passes through the wire 251 to be connected with FPC 26, and in catheter body 1's inner chamber was located to wire 251, miniature battery 25 externally arranged catheter body 1 one end of connecting the dislysate bag in, after the battery power is not enough, can conveniently, change the battery fast, the guarantee dialysis catheter can normally work for a long time.

A connecting part 13 extending along the axial direction is arranged on the inner side wall of the catheter body 1, the outer side wall of the strip-shaped liquid bag 3 is connected with the inner side wall of the catheter body 1 through the connecting part 13, and a lead 251 is arranged in the connecting part 13 to isolate the lead 251 from the dialysate; after the liquid in the strip-shaped liquid bag 3 is pumped out, the strip-shaped liquid bag 3 is tightly attached to the side wall in the inner cavity of the catheter body 1, so that the inner cavity of the catheter body 1 cannot be blocked, and the dialysis is ensured to be smoothly carried out.

The sealing shell 21 is provided with a first through hole 211, and the first through hole 211 is communicated with the catheter body 1 so as to facilitate the peritoneal dialysis solution to rapidly flow into the peritoneal cavity.

The glucose probe 22 is a platinum electrode with glucose oxidase, and the surface is a semi-permeable membrane.

One end of the glucose monitoring probe 2 is provided with a spherical support frame 27, the spherical support frame 27 is provided with a plurality of second through holes 271, and the glucose probe 22 is arranged in the cavity of the spherical support frame 27 so as to avoid the direct tissue contact between the glucose probe 22 and the peritoneal cavity and ensure the glucose probe 22 to normally detect the glucose concentration of the dialysate in the peritoneal cavity.

The spherical support frame 27 is made of corrosion-resistant metal so as to prolong the service life of the spherical support frame 27, and further increase the weight of the glucose monitoring probe 2, so that the glucose monitoring probe 2 and the dialysis area 10 sink in dialysate in a peritoneal cavity due to gravity, and the dialysis tube is prevented from floating.

The strip-shaped liquid bag 3 is filled with X-ray developing contrast agent, and the strip-shaped liquid bag 3 can be developed under an X-ray film, so that the position of the dialysis area 10 can be observed conveniently.

The strip-shaped liquid bag 3 is made of a nylon elastomer Pebax or natural latex, and the strip-shaped liquid bag 3 is filled or contracted by injecting or extracting liquid through the liquid injection port 31; the length of bar liquid bag 3 is not less than the length of dialysis district 10 on the pipe body 1, and when bar liquid bag 3 was filled up liquid and is inflated and expanded, all dialysis holes on dialysis district 10 can be sealed.

The working principle of the invention is as follows: when the dialysis is not carried out, the rubber plug 311 is pierced by using an injector, liquid is injected into the strip-shaped liquid bag 3 through the liquid injection port 31, the strip-shaped liquid bag 3 expands after being filled with the liquid, and the dialysis hole 11 can be sealed from the inside of the catheter body 1, so that tissues in peritoneal cavities such as omentum majus and the like can be prevented from blocking the dialysis hole 11, the peritoneal cavities can be isolated from the outside, the risks of infection and leakage are reduced, meanwhile, an X-ray developing contrast medium is added into the injection liquid of the strip-shaped liquid bag 3, the dialysis area 10 of the peritoneal dialysis tube can be developed under an X-ray film, and the position of the dialysis area 10 can be observed conveniently; during dialysis, the titanium alloy joint 12 is connected with an external connecting pipe of the peritoneal dialysis bag, the rubber plug 311 is pierced by a syringe, the strip-shaped liquid bag 3 is pumped out through the liquid injection port 31 to inject liquid, the strip-shaped liquid bag 3 contracts, the peritoneal dialysis liquid is dialyzed through the dialysis hole 11, the glucose concentration of the dialysis liquid in the peritoneal cavity is monitored by the glucose monitoring probe 2 in real time, and the monitored data is sent to the mobile terminal through the wireless transmission module 24, so that a doctor can know the concentration of the peritoneal dialysis liquid in real time, problems can be timely found and solved, and convenience and rapidness are realized; the corrosion-resistant metal spherical support frame 26 with a certain weight can not only prevent the glucose probe 22 from directly contacting with the tissues in the peritoneal cavity, but also realize that the glucose monitoring probe 22 sinks downwards due to gravity, so that the dialysis area 10 reaches the lower part of the peritoneal cavity to prevent tube floating.

The above examples are only for illustrating the technical solutions of the present invention, and not for limiting the same; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.

Claims

1. A peritoneal dialysis catheter characterized by: the glucose monitoring device comprises a catheter body (1), a glucose monitoring probe (2) and a strip-shaped liquid bag (3), wherein one end of the catheter body (1) is a dialysis area (10), a plurality of dialysis holes (11) are formed in the dialysis area (10), the other end of the catheter body is connected with an external dialysis liquid bag, one end of the catheter body (1) provided with the dialysis holes (11) is connected with the glucose monitoring probe (2), the strip-shaped liquid bag (3) is arranged in an inner cavity of the catheter body (1), the length of the strip-shaped liquid bag is not smaller than that of the dialysis area (10) on the catheter body (1), one end of the strip-shaped liquid bag (3) is provided with a liquid injection port (31), the liquid injection port (31) is arranged at one end of the catheter body (1) connected with the external dialysis liquid bag, and a rubber plug (311) is arranged at an opening of the liquid injection port (31); the glucose monitoring probe (2) comprises a sealing shell (21), a glucose probe (22), a data acquisition module (23), a wireless transmission module (24), a micro battery (25) and an FPC flexible board (26), wherein the data acquisition module (23), the wireless transmission module (24) and the FPC flexible board (26) are all arranged in a containing space of the sealing shell (21), the data acquisition module (23), the glucose probe (22), the wireless transmission module (24) and the micro battery (25) are electrically connected through the FPC flexible board (26), one end of the glucose probe (22) is connected with the FPC flexible board (26), and the other end of the glucose probe extends out of the sealing shell (21); the micro battery (25) is arranged on the outer wall of one end, close to the liquid injection port (31), of the catheter body (1), the micro battery (25) is connected with the FPC flexible board (26) through a conducting wire (251), and the conducting wire (251) is arranged in the inner cavity of the catheter body (1); a connecting part (13) extending along the axial direction is arranged on the inner side wall of the catheter body (1), the outer side wall of the strip-shaped liquid bag (3) is connected with the inner side wall of the catheter body (1) through the connecting part (13), and the lead (251) is arranged in the connecting part (13); the sealing shell (21) is provided with a first through hole (211), and the first through hole (211) is communicated with the catheter body (1); one end of the glucose monitoring probe (2) is provided with a spherical support frame (27), a plurality of second through holes (271) are arranged on the spherical support frame (27), and the glucose probe (22) is arranged in a cavity of the spherical support frame (27).

2. The peritoneal dialysis catheter of claim 1, wherein: the glucose probe (22) is a platinum electrode with glucose oxidase, and the surface of the glucose probe is a layer of semipermeable membrane.

3. The peritoneal dialysis catheter of claim 2, wherein: the spherical support frame (27) is made of corrosion-resistant metal.

4. The peritoneal dialysis catheter of claim 1, wherein: and an X-ray developing contrast agent is added into the liquid injected by the strip-shaped liquid bag (3).

5. The peritoneal dialysis catheter of claim 1, wherein: the strip-shaped liquid bag (3) is made of a nylon elastomer Pebax or natural latex.