CN110037931A - A kind of infant's efficient moisture-retention moisturizing lotion of the component containing antipollution - Google Patents

Abstract

The invention discloses a kind of infant's efficient moisture-retention moisturizing lotions of component containing antipollution, it includes the emulsifier with moistening effect and green plants source, the grease with significant moisturizing effect and plant origin, the water soluble humectants with efficient moisture-retention effect, extract with contamination resistance and plant origin etc. for main composition that it, which is formulated, and there is moisturizing lotion of the invention the ability of efficient moisture-retention to be capable of providing resistant to pollution effect simultaneously.

Description

A kind of infant's efficient moisture-retention moisturizing lotion of the component containing antipollution

Technical field

The present invention relates to non-stimulated extremely natural, the mild milky lotion of a kind of pair of skin.More particularly, the present invention relates to And be a kind of component containing antipollution infant's efficient moisture-retention moisturizing lotion.

Background technique

The skin texture of baby is not yet developed completely, does not have many functions of adult skin, at least needs 3 years time Can develop as adult.Infant's skin disease resistance is poor, is easy to be infected by bacterial: due to skin undeveloped mature, institute It is weak with function of immune system, the first line of defence that human body resists pathogenic bacteria cannot be become as adult, only by skin surface One layer of natural acidic film protects skin, it is easy to be infected by bacterial, or allergic reaction occurs, such as erythema, erythema, bubble Deng；The average surface area of infant skin is 2500 square centimeters, and 5 kilograms of average weight, the ratio between the two is 1:500；Adult skin Average surface area be 18000 square centimeters, 65 kilograms of average weight, the ratio between the two be 1:270, therefore, for same amount Washing the absorption of shield product must be more than adult, meanwhile, also much strong to the reaction of allergin or toxic substance, rich blood vessel is non- It is often fragile, it will bleeding due to trauma by slight physics sexual stimulus.The skin of infant only has the thickness of adult skin 1/10th, table Skin is cell monolayer, and adult is multi-layer cellular.The cuticula of infant skin is not yet reached maturity, corium and fibr tissue compared with Thin, skin is very young tender, sensitive, and the ability for resisting dry environment is weaker.The immune system of baby itself is not perfect enough, resists Power is weak, therefore is easier to skin allergy occur.Keratoderma is the first barrier that body resists external environment stimulation, air Pollutant mainly damages keratoderma by oxidative pressure and causes protein carbonyl, to accelerate skin aging, or even causes The various stiff reactions of skin, so, to protect the delicate skin of baby, a kind of infant with contamination resistance is developed hereby The moisturizing lotion of efficient moisture-retention ability, the raw material preferred plant for safety, mildness and the feature of environmental protection for improving product, selection come Source.

Summary of the invention

To overcome above-mentioned deficiency, the present invention provides a kind of infant's efficient moisture-retention moisturizing lotions of component containing antipollution. The technical solution adopted by the present invention to solve the technical problems is: a kind of infant's efficient moisture-retention milky lotion of the component containing antipollution Liquid, which is characterized in that be grouped as comprising following group by weight percentage:

The pure and mild C12-20 alkyl glucoside 2%~5% of C14-22；

Shea butter 2%~6%；

Carbohydrate isomer 0.5%~2%；

Camellia flower extract 0.1%~5%；

Vegetalitas moisturizer 2%~10%；

Vaseline 1%~4%；

Glycerol 5%~20%；

Polyacrylate cross-linked polymer -6 0.1%~0.6%；

Ethylhexyl palmitate 4%~10%；

Polydimethyl siloxanes/polydimethy siloxanes alcohol/cyclotetrapolydimethylsiloxane 1%~3%；

Decoyl hydroximic acid 0.01%~0.2%；

Parahydroxyacet-ophenone 0.05%~0.3%.

Preferred vegetalitas moisturizer includes Lin Lan profit dew and tremella polysaccharides.

A kind of preferred infant's efficient moisture-retention moisturizing lotion of the component containing antipollution, comprising it is following by weight percentage Group is grouped as:

The pure and mild C12-20 alkyl glucoside 2% of C14-22；

Shea butter 2%；

Carbohydrate isomer 0.5%；

0 .1% of camellia flower extract；

Tremella polysaccharides 0.8%；

Lin Lan profit dew 2%；

Vaseline 1%；

Glycerol 8%；

Polyacrylate cross-linked polymer -6 0.3%；

Ethylhexyl palmitate 4%；

Polydimethyl siloxanes/polydimethy siloxanes alcohol/cyclotetrapolydimethylsiloxane 1.5%；

Decoyl hydroximic acid 0.1%；

Parahydroxyacet-ophenone 0.2%.

Daily essence 0.05%；

Water adds to 100%.

Not only property is mild by the present invention, low stimulation, but also has good ph stability and cold-resistant heat-resistant stability Energy.

Detailed description of the invention:

Fig. 1 is skin wound repair grade form.

Fig. 2 is skin irritatin strength grading table.

Fig. 3 is test result table.

Fig. 4 is moisture of skin test data.

Fig. 5 is moisture retention analysis chart.

Fig. 6 is that skin water loss tests table.

Fig. 7 is water lock analysis chart.

Fig. 8 is facial susceptibility application form.

Fig. 9 is degree of drying application form.

Figure 10 is facial susceptibility application form.

Figure 11 is degree of drying application form.

Specific embodiment:

Below with reference to embodiment to further detailed description of the present invention, embodiments of the present invention are not limited thereto.

Embodiment 1

By raw material by following proportional arrangement (being free of water lock magnetite)

Embodiment 2

By raw material by following proportional arrangement (being free of vaseline)

Raw material are pressed into following proportional arrangement

Raw material is added in corresponding container by said ratio, is mixed with it under suitable environmental condition, is made Any conventional mixing apparatus well known in the art can be used when standby, such as: emulsifying homogeneous pot.The sum that oil is molten is needed when mixing Water-soluble difference Hybrid Heating is to 80 DEG C, and then oil is mutually and homogeneous is mixed in water phase, and plant extract is added when cooling to 45 DEG C Object and daily essence.

The detailed description of preferred technical solution

The first ingredient of the invention is at least to contain a kind of emulsifier with moistening effect and green plants source. The mixture of the pure and mild C12-20 alkyl glucoside of C14-22 is the fatty alcohol that origin is derived from natural rapeseed oil, palm oil or coconut oil It is formulated with the glucose from wheat by special process, is 100% rechargeable energy, which is based on liquid crystal The APG active emulsifier of structure is a kind of more comprehensive new non-ionic surfactants of performance, has both conventional nonionic and yin The characteristic of ionic surface active agent.Liquid crystal structure assigns the ingredient with multilayered structure similar with epidermis lipid, in skin table Skin forms physics water-retaining film (liquid crystal), has excellent skin compatibility, can strengthen lipid barrier, to rebuild structure, reduces Scalp moisture is lost.Through testing, which is capable of providing lasting 5 hours moistening effects；Therefore currently preferred that there is guarantor The emulsifier in wet effect and green plants source is the mixture of the pure and mild C12-20 alkyl glucoside of C14-22.

Second of ingredient of the invention is the grease at least containing a kind of plant origin with significant moisturizing effect. The indices that shea butter secretes grease with human sebaceous are closer to, and contain non-saponified ingredient abundant, are easy to human body suction Receive, season cracking can be prevented, further restore and keep the natural elasticity of skin, be it is a kind of can effectively anti-aging active matter Matter.The main component of shea butter is triglycerides (containing a certain number of linoleic acid) and unsaponifiable matters, wherein glycerol three The content of ester is 80% or so, and the content of unsaponifiable matters has according to the difference of season, the place of production and extraction and refining methd Changed, part unsaponifiable matters contained by shea butter used in this application are the cinnamic acid of spinasterol and stigmasterol Ester, these are the bioprecursors of certain sterols and steroid (such as VD, hormone), affect the growth of skin histology； Contained another part unsaponifiable matters are the cinnamate of terpenol, the flat pure and mild resinol of plumage, this is cured promotion skin wound Close and anti-inflammatory have good effect, contained by latex materials with anti-ultraviolet function, therefore can also prevent light aging. For shea butter tests prove that it is with good moisturizing effect, the time of moisture-keeping function is 8 hours.Adhere to using can Moist effect is played to epidermis, and there is preferable moistening effect.Accordingly, it is preferred that the plant with significant moisturizing effect The grease in object source is shea butter.

The third ingredient of the invention is at least to contain a kind of water soluble humectants with efficient moisture-retention effect.Preferably It can continue the water lock magnetite (carbohydrate isomer) of moisturizing in 72 hours.The moisturizer is from vegetalitas D- glucose sugar, tool It is made of unique, it is similar with the composition of carbohydrate in human skin (NMF), and make it with the unique binding mechanism of skin It will not be rinsed in use process, can accomplish instant, deep moisturizing, and form reservoir.After tested, water lock magnetite energy Enough epidermal cell is helped more preferably to be hydrated, can promote the hydration and moisture holding capacity of cuticula in a short time, therefore in Skin can be improved for a long time because of the decortication phenomenon of dry initiation and enhance the barrier function of skin.And then improves and drawn by dry skin The tight, itch and shouting pain risen, promotes the flatness of skin, improves the pliability of skin, to obtain more comfortable skin Impression and more healthy skin appearance.

4th kind of ingredient of the invention is the extract containing a kind of plant origin with contamination resistance.Winter cypress is One of most notable Theaceae species, the also referred to as rose in winter, are a kind of dungarungas to bloom, and winter cypress flower extract contains Nutriment abundant has potent antioxidation, while having the function of anti-inflammatory and promoting collagen synthesis, also It can inhibit the effect of the oxidative stress as caused by heavy metallic mixture, so as to improve dermal composition and dermis density, and the raw material Stability itself is good, even if being also able to maintain stabilization under extreme ultraviolet light and heat condition.Research shows that winter cypress flower extract Can effective Keratoderma layer oxidative stress caused by contaminant restraining (polycyclic aromatic hydrocarbon & heavy metallic mixture), to inhibit true Collagen in cortex decomposes, and reaches crease-resistant effect；It can effective skin caused by contaminant restraining (10 μm and 2.5 μm) Cuticular layer response to oxidative stress increases the survival rate of keratinocyte.Skin plays from physics and chemical action not human body Benefit influences, and the increase of environmental pollution causes human skin to be encroached on；Continuous skin is exposed to dirt, dust, free radical, ultraviolet It will lead to the decline of dermal inflammatory skin barrier function, premature aging in line and smog pollution material；Infant's skin barrier function ratio It is adult much weaker, therefore the behave for resisting pollutant should be done from the nursing of infant.

In addition, vegetalitas moisturizer contained in the formula of the application is Lin Lan profit dew and tremella polysaccharides.Lin Lan profit dew comes In various plants, by HERBA DENDROBII stem extraction, aloe barbadensis Miller leaf extract, kuh-seng root extract, lycium barbarum fruit Extract and Echinacea angustifolia extract refine, and act on basal layer, and aquaporin AQP3 can be activated to express, and inhibit transparent Matter acid enzyme (inflammatory reaction participant) activity, and a polyprotein (precursor of natural moisturizing factor), sluice protein expression are improved, lead to Cross " mend, is clear, solid, feeding " moisturizing new approaches, timely, long-acting raising skin moisture content.Tremella polysaccharides are the main work in tremella Property ingredient, can make skin have good smooth feeling and moist feeling, do not shrink, it is dry and comfortable not tight, play a protective role to skin, Increase elasticity.By inhibiting the peroxidization of cytolipin, to prevent skin aging；Promote elastic cell's growth；It reduces Injury of the UV to skin；Epidermal cell is activated, photo damaged skin is repaired；Accelerate skin regeneration；Wrinkle-chasing goes wrinkle to reduce skin lines With it is dry and cracked.

Solid grease used in this application is preferably vaseline.Vaseline can be alleviated chapped caused by dry skin It splits, peeling, which will not infiltrate into cuticula, oiliness protective film only be formed on the skin, in cuticula and following epidermis It is integrated, forms the protection walls for hindering foreign body intrusion, less transepidermal water can thoroughly be protected by cuticula while volatilization Generated defense function reduces the injury that floating material, dust and chemical substance in air bring skin；Villus after alleviation is dry As cuticula, to it with emollescence.Herein, vaseline and shea butter collective effect being capable of dual moist epidermis fleshes Skin, less water loss；Vaseline and camellia flower extract collective effect, can be improved skin and resist energy to environmental stimuli Power is worked along both lines, and the delicate skin of baby is protected.

Traditional moisturizer use herein is glycerol, also affects this moisturizing lotion while providing moisture-keeping functions Skin sense；Used thickener is polyacrylate cross-linked polymer -6 for having fine tolerance to electrolyte, used Liquid fat is ethylhexyl palmitate, it is intended to which equilibrium formula skin sense provides salubrious not sticky, the use feeling of moist non-greasy By；Used skin sense regulator is dimethyl silicone polymer, dimethiconol and cyclotetrapolydimethylsiloxane Compound, it is desirable to provide smooth use feeling, used chelating agent are decoyl hydroximic acid, it is intended to chelate iron in water, calcium, The metal ions such as magnesium keep its chelate soluble in water, play the role of softening the water hardness, thus stable prod framework；Institute The antioxidant used is parahydroxyacet-ophenone, it is intended to reduce or eliminate the risk that grease is oxidized, and parahydroxyacet-ophenone It is used in conjunction with decoyl hydroximic acid, there is good coordinate repression to the microorganism in product.

A kind of infant's efficient moisture-retention moisturizing lotion of component containing antipollution described herein meets national row through examining Industry standard, indices comply fully with sanitary quality standard and the security requirement of national regulation.

Above mentioned skin care compositions can by by required ingredient in suitable container, in suitable environment Under the conditions of make its mixing to prepare, any conventional mixing apparatus well known in the art can be used in when preparation, such as: emulsifying homogeneous pot Deng.It is needed when mixing the molten and water-soluble difference Hybrid Heating of oil to 80 DEG C or more, then oil is mutually mixed with water phase equal Matter is added skin sense regulator when cooling to 55 DEG C, plant extracts etc. is added after cooling to 45 DEG C.

Irritation test

The specific method and result of multiple acute skin irritation test are as follows:

Tested material: tested material is a kind of infant's efficient moisture-retention moisturizing lotion of component containing antipollution in this test, without It dissolves not diluted.

Experimental animal and feeding environment:

Used in this test experimental animal be adult, healthy, skin zero damage cavy weight (250~300g), Female and male, but jenny should be unpregnancy and not farrow.Experimental animal at least with 4, will such as clarify certain A little suspicious reactions then need to increase experimental animal number.Experimental animal answers single cage to raise, and animal will be in experimental animal room ring before testing The 3d time is at least adapted in border (laboratory temperature: 20~24 DEG C, relative humidity 60~70%).Experimental animal and experimental animal room National respective specified should be met.Conventional feed is selected, drinking-water does not limit.

Multiple skin irritation test step:

Experimental animal back backbone two sides coat is cut before 1 test, unhairing range is respectively 3cm × 3cm, application area 2.5cm×2.5cm。

2 take moisturizing lotion about 0.5g to be applied on the skin of side, and the other side is not smeared as blank control.1 is smeared daily It is secondary, continuously smear 14d.Since second day, cropping is answered before smearing every time, it is tested with water or nonirritant solvent cleaning residual Object.Observation after one hour by Fig. 1 as a result, score, check plot and trial zone are equally handled.

2.4.3 evaluation of result: being calculated according to the following formula daily every animal average integral, determines that skin irritatin is strong with Fig. 2 Degree.Test result is shown in Fig. 3.

It can be seen that the moisturizing lotion is nontoxic to skin non-stimulated.

Moisture of skin tests (Corneometer): test value is higher, and moisture retention is better, sees Fig. 4

From fig. 5, it can be seen that each product moisture content is improved, moisture retention: 1 > embodiment of embodiment, 2 > embodiment 3。

Significance analysis is carried out to 1 data of table using the t- method of inspection.The result shows that with blank comparing embodiment 1, implementation There is significant difference (p≤0.05) in 1-6h in the profit of example 2 and embodiment 3 such as lotion, illustrate all there is conspicuousness moisturizing effect Fruit.

Skin water loss tests (Tewameter): test value is lower, and dehydration is fewer, and water lock is better, sees Fig. 6.

From figure 7 it can be seen that water lock effect: 1 > embodiment of embodiment, 2 > embodiment 3.

Significance analysis is carried out to Fig. 2 data using the t- method of inspection.The result shows that embodiment 1 is in 1- compared with blank 6h illustrates have conspicuousness water lock effect there are significant difference (p≤0.05).

From above-mentioned two groups of test datas and result it is found that the moisture retention and water lock of embodiment 1 are above embodiment 2 and reality Apply example 3, it can be seen that embodiment 1 has the function of efficient moisture-retention.

The investigation of antipollution effect

In order to verify whether the application has resistant to pollution effect, the application personnel are to 60 daily walkings or working of riding Female volunteers carry out investigation on probation in 56 days by a definite date, wherein 30 it is on probation be the present embodiment 1 sample, be A group, residue 30 What position was tried out is 1 comparative sample of embodiment for being not added with camellia flower extract, is B group.A group investigation result such as Fig. 8, Fig. 9；B group is adjusted Come to an end fruit such as Figure 10, Figure 11.

Skin barrier is to be collectively constituted between the corneocyte of skin and cell by lipid and natural moisturizing factor, skin Skin is chronically at dry desiccation, and to will lead to skin barrier impaired, so that external substance and microorganism is organic takes advantage of, Jin Erying Skin health is rung, allergy is caused.Above-mentioned survey data explanation, A group (embodiment 1: sample flower extract containing camellia on probation) aspiration After person is using two skin periods, while skin dryness is obviously improved, tender subject also obtains biggish improvement, Illustrate to block outside contamination and harmful substance to a certain extent.And (1 comparative sample of embodiment: sample on probation is free of camellia to B group Flower extract), improve in dry skin problem preferably, A group is markedly less than in tender subject.It can be seen that embodiment 1 is in anti-pollution Dye aspect has the effect of certain.

The above display describes basic principles and main features and advantages of the present invention of the invention.The technology people of the industry Member is it should be appreciated that the present invention is not limited to the above embodiments, and the above embodiments and description only describe this hairs Bright principle, under the premise of not departing from the present invention and range, various changes and improvements may be made to the invention, these change and change Into all fall within the protetion scope of the claimed invention.The claimed scope of the invention is by appended claims and its equivalent It defines.

Claims (3)

1. a kind of infant's efficient moisture-retention moisturizing lotion of component containing antipollution, which is characterized in that include following percentage by weight The group of ratio is grouped as:

The pure and mild C12-20 alkyl glucoside 2%~5% of C14-22；

Shea butter 2%~6%；

Carbohydrate isomer 0.5%~2%；

Camellia flower extract 0.1%~5%；

Vegetalitas moisturizer 2%~10%；

Vaseline 1%~4%；

Glycerol 5%~20%；

Polyacrylate cross-linked polymer -6 0.1%~0.6%；

Ethylhexyl palmitate 4%~10%；

Polydimethyl siloxanes/polydimethy siloxanes alcohol/cyclotetrapolydimethylsiloxane 1%~3%；

Decoyl hydroximic acid 0.01%~0.2%；

Parahydroxyacet-ophenone 0.05%~0.3%.

2. infant's efficient moisture-retention moisturizing lotion of a kind of component containing antipollution according to claim 1, it is characterized in that: institute The vegetalitas moisturizer stated includes Lin Lan profit dew and tremella polysaccharides.

3. a kind of infant's efficient moisture-retention moisturizing lotion of component containing antipollution according to claim 1, characterized in that packet It is grouped as containing following group by weight percentage:

The pure and mild C12-20 alkyl glucoside 2% of C14-22；

Shea butter 2%；

Carbohydrate isomer 0.5%；

Camellia flower extract 0.1%；

Tremella polysaccharides 0.8%；

Lin Lan profit dew 2%；

Vaseline 1%；

Glycerol 8%；

Polyacrylate cross-linked polymer -6 0.3%；

Ethylhexyl palmitate 4%；

Polydimethyl siloxanes/polydimethy siloxanes alcohol/cyclotetrapolydimethylsiloxane 1.5%；

Decoyl hydroximic acid 0.1%；

Parahydroxyacet-ophenone 0.2%.

Daily essence 0.05%；

Water adds to 100%.