CN110025401A - A kind of intravascular stent with adsorbable overlay film - Google Patents
A kind of intravascular stent with adsorbable overlay film Download PDFInfo
- Publication number
- CN110025401A CN110025401A CN201910303672.2A CN201910303672A CN110025401A CN 110025401 A CN110025401 A CN 110025401A CN 201910303672 A CN201910303672 A CN 201910303672A CN 110025401 A CN110025401 A CN 110025401A
- Authority
- CN
- China
- Prior art keywords
- overlay film
- intravascular stent
- adsorbable
- carrier unit
- biological
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/88—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements formed as helical or spiral coils
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0076—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof multilayered, e.g. laminated structures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00389—The prosthesis being coated or covered with a particular material
- A61F2310/0097—Coating or prosthesis-covering structure made of pharmaceutical products, e.g. antibiotics
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Materials For Medical Uses (AREA)
Abstract
The invention discloses a kind of intravascular stents with adsorbable overlay film, are related to medical instruments field, mainly for solving the problems, such as that the existing intravascular stent support effect with absorbable overlay film is poor；This has the intravascular stent of adsorbable overlay film, including carrier unit, the carrier unit is wrapped on Body of pillar, the carrier unit includes metal monofilament and knitted body, the metal monofilament is helical form, it is attached between the metal monofilament by knitted body, is braiding cavity between the metal monofilament and knitted body, the carrier unit also passes through fastener and is fixed on Body of pillar；It further include coating layer, the coating layer is followed successively by the first biological overlay film, drug-loaded layer and the second biological overlay film from outside to inside, improves the support effect of intravascular stent and to the therapeutic effect that can be improved to site of disease.
Description
Technical field
The present invention relates to a kind of medical instruments field, specifically a kind of intravascular stent with adsorbable overlay film.
Background technique
Intravascular stent refers to that on the basis of the forming of lumen balloon expandable, it is narrow to reach support to be placed in inner support in lesion
Narrow occlusion section blood vessel reduces blood vessel elasticity retraction and moulding again, the purpose for keeping lumen blood flow unobstructed.Part inner support also has
The effect of pre- anti-restenosis.It is broadly divided into coronary artery bracket, cerebrovascular stent, renal artery stent, aortic stent etc..
Application publication number discloses a kind of intravascular stent with absorbable overlay film, including tubular bracket and coating layer；Pipe
Shape bracket is flexible tubular structure, including the proximal end, middle section and distal end successively arranged；Coating layer is coated on tubular bracket
On；Coating layer is made of degradable high polymer material, this structure support effect and bad in use, in use process
In, between tubulose with friction is small at illness be easy to occur intravascular stent displacement.
Summary of the invention
The purpose of the present invention is to provide a kind of intravascular stents with adsorbable overlay film, solve existing with absorbable
The problem of the intravascular stent support effect difference of overlay film.
To achieve the above object, the invention provides the following technical scheme:
A kind of intravascular stent with adsorbable overlay film, including carrier unit, the carrier unit is wrapped on Body of pillar, described
Carrier unit includes metal monofilament and knitted body, and the metal monofilament is helical form, passes through knitted body between the metal monofilament
It is attached, is braiding cavity between the metal monofilament and knitted body, the carrier unit also passes through fastener and is fixed on branch
On cylinder.
In a kind of optinal plan: the carrier unit is helical form, the quantity at least two of the carrier unit, institute
Body of pillar is stated as cylinder.
In a kind of optinal plan: the material of the fastener is Nitinol.
In a kind of optinal plan: the quantity of the metal monofilament is two, and the material of the metal monofilament includes metal
Tantalum, Nitinol and titanium-base alloy.
In a kind of optinal plan: the material of the knitted body is the composite material of metal, terylene and acrylic fibers.
In a kind of optinal plan: the shape of the braiding cavity is rectangle or triangle.
A kind of intravascular stent with adsorbable overlay film further includes coating layer including above-mentioned intravascular stent, the overlay film
Layer is followed successively by the first biological overlay film, drug-loaded layer and the second biological overlay film from outside to inside.
In a kind of optinal plan: the drug-loaded layer is between the first biological overlay film and the second biological overlay film, and described second
Anti-slip layer is additionally provided on the inside of biological overlay film.
In a kind of optinal plan: the described first biological overlay film, the second biological overlay film and anti-slip layer are degradation material.
Compared to the prior art, beneficial effects of the present invention are as follows:
The present invention is by the way that carrier unit to be wrapped on Body of pillar, then is fixed by fastener, can be improved between unit
Stability；By spiral helicine carrier unit, the frictional force at carrier unit and illness can be improved, prevent carrier unit sliding
Out at illness；By being equipped with drug-loaded layer in coating layer, therapeutic effect can be improved to drug improvement is carried out at illness.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the intravascular stent of the intravascular stent with adsorbable overlay film.
Fig. 2 is another canoe structure chart of the intravascular stent with adsorbable overlay film.
Fig. 3 is the enlarged drawing of a-quadrant in the intravascular stent with adsorbable overlay film.
Fig. 4 is the structure chart that the intravascular stent another kind with adsorbable overlay film weaves cavity.
Fig. 5 is the structural schematic diagram of the intravascular stent with adsorbable overlay film.
Fig. 6 is the structural schematic diagram of coating layer in the intravascular stent with adsorbable overlay film.
Fig. 7 is the perspective view of another canoe in the intravascular stent with adsorbable overlay film.
Appended drawing reference annotation: 1- carrier unit, 2- Body of pillar, 3- coating layer, 4- fastener, 11- metal monofilament, 12- are compiled
Knit body, 13- braiding cavity, the biological overlay film of 31- first, 32- drug-loaded layer, 33- second biological overlay film, 34- anti-slip layer.
Specific embodiment
Following embodiment can be described in detail the present invention in conjunction with attached drawing, in attached drawing or explanation, similar or identical part
Using identical label, and in practical applications, shape, thickness or the height of each component can be expanded or shunk.Institute of the present invention
Each embodiment enumerated is only to illustrate the present invention, is not used to limit the scope of the present invention.It is made for the present invention any aobvious
And modification easy to know or change are without departure from spirit and scope of the invention.
Embodiment 1
Referring to Fig. 1, in the embodiment of the present invention, a kind of intravascular stent with adsorbable overlay film, including carrier unit 1, it is described
The quantity of carrier unit 1 is two, and the carrier unit 1 is helical form, and spiral forms one together between the carrier unit 1
The stable support body of stock, the carrier unit 1 is wrapped on Body of pillar 2, by being wrapped in two even more than carrier unit 1
On Body of pillar 2, the stability between carrier unit 1 can be improved, while the deformation of carrier unit 1 can be prevented, when blood vessel branch
Frame enters in blood vessel, can be to certain extruding force is caused between blood vessel, when preventing for carrier unit 1 because of the shrinkage of blood vessel
When deformability difference, the effect of intravascular stent is very small.
Further, when the quantity more than two of the carrier unit 1, it can be improved the spiral force between carrier unit 1,
The stability between carrier unit 1 further increases at this time, the quantity at least two of the carrier unit 1, the bracket list
Member 1 and the length of Body of pillar 2 are determined according to the actual conditions of patient；The Body of pillar 2 is cylinder, is facilitated bracket list
Member 1 is wound.
Further, the carrier unit 1 includes metal monofilament 11 and knitted body 2, and the quantity of the metal monofilament 11 is
Two, the material of the metal monofilament 11 includes but is not limited to metal tantalum, further includes Nitinol and titanium-base alloy etc., the gold
Category monofilament 11 is helical form, is attached between the metal monofilament 11 by knitted body 12, and the knitted body 12 is by two gold
Belong to monofilament 11 and be wound in stable helical form, the material of the knitted body 12 is the composite material of metal, terylene and acrylic fibers, described
It is braiding cavity 13 between metal monofilament 11 and knitted body 12, the shape of the braiding cavity 13 determines the steady of carrier unit 1
Qualitative, the shape of the braiding cavity 13 is rectangle, is capable of providing stability well, the amount of required knitted body 12 is less, institute
State knitted body 12 density it is larger when, stability also can be fine.
Referring to Fig. 3, the shape of the braiding cavity 13 can also be triangle, when the shape of braiding cavity 13 is triangle
When shape, it is capable of providing better stability, the shape of the braiding cavity 13 is not only rectangle and triangle, can also be it
Its polygon.
Further, the carrier unit 1 is also fixed on Body of pillar 2 by fastener 4, improves carrier unit 1 therewith
The stability of Body of pillar 2 can prevent carrier unit 1 from skidding off from Body of pillar 2, and the material of the fastener 4 is Nitinol.
Referring to Fig. 2, can also be directly wound by knitted body 12 on the Body of pillar 2, without being fabricated to spiral
The effect that shape can reduce cost, but use can be than using helical metal monofilament 11 poor.
Further, intravascular stent in the production process, when using spiral helicine metal monofilament 11, first by metal monofilament
11 turn around into suitable shape, then two root unit metal monofilaments 11 are carried out establishment supporting support unit 1 by braider, then will
Two or more carrier units 1 are wrapped on Body of pillar 2, are fastened by fastener 4；When not using helical form monofilament,
Directly braided fabric is wrapped on Body of pillar 2, after the completion of to be produced, is carried out disinfection by thimerosal, is finally placed on nothing
It is saved in bacterium case, is further taken out when it is desired to be used, guarantee the cleanliness of intravascular stent.
Embodiment 2
Please refer to Fig. 4~6, a kind of intravascular stent with adsorbable overlay film further includes coating layer 3, the coating layer 3 from outside to
It is inside followed successively by the first biological overlay film 31, drug-loaded layer 32 and the second biological overlay film 33, the described first biological overlay film 31 is in coating
The intravascular stent in portion, the drug-loaded layer 32 is between the first biological overlay film 31 and the second biological overlay film 33, when the first biological overlay film
31 degradation after, the drug in the drug-loaded layer 32 volatilizees, can to illness go out treat, solve many fraction medicines without
The problem of method directly reaches can be applied to many positions.
Further, it is additionally provided with anti-slip layer 34 on the inside of the described second biological overlay film 33, intravascular stent is placed on coating layer 3
It is interior, it can prevent intravascular stent from skidding off in coating layer 3 by the anti-slip layer 34, intravascular stent enters initial stage, needs first to degrade
Coating layer 3 provides protection and supporting role well by anti-slip layer 34.
Further, the described first biological overlay film 33 of biological overlay film 31, second and anti-slip layer 34 are degradation material, when
After the drug of drug-loaded layer 32 is absorbed, can degrade in time, by intravascular stent exposure, preferably carry out using.
The working principle of the invention is: woven carrier unit 1 being wrapped on Body of pillar 2, is carried out by fastener 4
It is fixed, then carrier unit 1 and Body of pillar 2 are wrapped up by coating layer 3, then whole will be sent at illness, go out in illness, first the
One biological overlay film 31 is degraded, and 32 drug of drug-loaded layer is absorbed, and then the second biological overlay film 33 and anti-slip layer 34 are also degraded, at this time
Carrier unit 1 is exposed, and plays a supporting role.
The above, the only specific embodiment of the disclosure, but the protection scope of the disclosure is not limited thereto, it is any
Those familiar with the art can easily think of the change or the replacement in the technical scope that the disclosure discloses, and should all contain
It covers within the protection scope of the disclosure.Therefore, the protection scope of the disclosure should be subject to the protection scope in claims.
Claims (9)
1. a kind of intravascular stent with adsorbable overlay film, including carrier unit (1), which is characterized in that the carrier unit (1)
It is wrapped on Body of pillar (2), the carrier unit (1) includes metal monofilament (11) and knitted body (2), the metal monofilament (11)
For helical form, it is attached between the metal monofilament (11) by knitted body (12), the metal monofilament (11) and knitted body
It (12) is braiding cavity (13) between, the carrier unit (1) is also fixed on Body of pillar (2) by fastener (4).
2. the intravascular stent according to claim 1 with adsorbable overlay film, which is characterized in that the carrier unit (1)
For helical form, the quantity at least two of the carrier unit (1), the Body of pillar (2) is cylinder.
3. the intravascular stent according to claim 1 with adsorbable overlay film, which is characterized in that the fastener (4)
Material is Nitinol.
4. the intravascular stent according to claim 1 with adsorbable overlay film, which is characterized in that the metal monofilament (11)
Quantity be two, the material of the metal monofilament (11) includes metal tantalum, Nitinol or titanium-base alloy.
5. the intravascular stent according to claim 1 with adsorbable overlay film, which is characterized in that the knitted body (12)
Material is the composite material of metal or terylene and acrylic fibers.
6. the intravascular stent according to claim 1 with adsorbable overlay film, which is characterized in that the braiding cavity (13)
Shape be rectangle or triangle.
7. the intravascular stent according to claim 1 with adsorbable overlay film, which is characterized in that it further include coating layer (3),
The coating layer (3) is followed successively by the first biological overlay film (31), drug-loaded layer (32) and the second biological overlay film (33) from outside to inside.
8. the intravascular stent according to claim 7 with adsorbable overlay film, which is characterized in that drug-loaded layer (32) position
Between the first biological overlay film (31) and the second biological overlay film (33), anti-slip layer is additionally provided on the inside of the described second biological overlay film (33)
(34).
9. the intravascular stent according to claim 7 with adsorbable overlay film, which is characterized in that the first biological overlay film
(31), the second biological overlay film (33) and anti-slip layer (34) are degradation material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910303672.2A CN110025401A (en) | 2019-04-16 | 2019-04-16 | A kind of intravascular stent with adsorbable overlay film |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910303672.2A CN110025401A (en) | 2019-04-16 | 2019-04-16 | A kind of intravascular stent with adsorbable overlay film |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110025401A true CN110025401A (en) | 2019-07-19 |
Family
ID=67238584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910303672.2A Pending CN110025401A (en) | 2019-04-16 | 2019-04-16 | A kind of intravascular stent with adsorbable overlay film |
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| Country | Link |
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| CN (1) | CN110025401A (en) |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN203564386U (en) * | 2013-09-12 | 2014-04-30 | 徐贵丽 | Medical orifice support capable of slowly releasing medicine |
| CN105188790A (en) * | 2013-03-15 | 2015-12-23 | 波士顿科学国际有限公司 | Anti-migratory stent coating |
| CN106456344A (en) * | 2014-04-02 | 2017-02-22 | 波士顿科学国际有限公司 | Covered endoscopic stents with adhesion elements |
| CN107343826A (en) * | 2016-05-05 | 2017-11-14 | 中国人民解放军第二军医大学 | New Pancreatic duct metal support |
| CN206745486U (en) * | 2017-01-06 | 2017-12-15 | 青岛市第三人民医院 | A kind of intravascular stent for preventing reangiostenosis |
| CN107847331A (en) * | 2015-07-27 | 2018-03-27 | 太雄医疗器株式会社 | Support with improved antiskid function |
| CN108420576A (en) * | 2018-04-02 | 2018-08-21 | 杨敏 | A kind of compartment is anti-skidding and can be with the intravascular stent of chronic drug |
-
2019
- 2019-04-16 CN CN201910303672.2A patent/CN110025401A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105188790A (en) * | 2013-03-15 | 2015-12-23 | 波士顿科学国际有限公司 | Anti-migratory stent coating |
| CN203564386U (en) * | 2013-09-12 | 2014-04-30 | 徐贵丽 | Medical orifice support capable of slowly releasing medicine |
| CN106456344A (en) * | 2014-04-02 | 2017-02-22 | 波士顿科学国际有限公司 | Covered endoscopic stents with adhesion elements |
| CN107847331A (en) * | 2015-07-27 | 2018-03-27 | 太雄医疗器株式会社 | Support with improved antiskid function |
| CN107343826A (en) * | 2016-05-05 | 2017-11-14 | 中国人民解放军第二军医大学 | New Pancreatic duct metal support |
| CN206745486U (en) * | 2017-01-06 | 2017-12-15 | 青岛市第三人民医院 | A kind of intravascular stent for preventing reangiostenosis |
| CN108420576A (en) * | 2018-04-02 | 2018-08-21 | 杨敏 | A kind of compartment is anti-skidding and can be with the intravascular stent of chronic drug |
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