CN110015703B - Healthy skin-beautifying filter material and preparation method thereof - Google Patents

Healthy skin-beautifying filter material and preparation method thereof Download PDF

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Publication number
CN110015703B
CN110015703B CN201910354976.1A CN201910354976A CN110015703B CN 110015703 B CN110015703 B CN 110015703B CN 201910354976 A CN201910354976 A CN 201910354976A CN 110015703 B CN110015703 B CN 110015703B
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filter material
healthy skin
vitamin
hyaluronic acid
polyglutamic acid
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CN110015703A (en
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徐俊斌
陆海涛
杨跃滨
简良荣
陈希敏
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Xiamen EASO Co Ltd
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Xiamen EASO Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/676Ascorbic acid, i.e. vitamin C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/88Polyamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • CCHEMISTRY; METALLURGY
    • C02TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02FTREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F1/00Treatment of water, waste water, or sewage
    • C02F1/001Processes for the treatment of water whereby the filtration technique is of importance
    • CCHEMISTRY; METALLURGY
    • C02TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02FTREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F1/00Treatment of water, waste water, or sewage
    • C02F1/68Treatment of water, waste water, or sewage by addition of specified substances, e.g. trace elements, for ameliorating potable water
    • CCHEMISTRY; METALLURGY
    • C02TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02FTREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F5/00Softening water; Preventing scale; Adding scale preventatives or scale removers to water, e.g. adding sequestering agents
    • CCHEMISTRY; METALLURGY
    • C02TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02FTREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F2101/00Nature of the contaminant
    • C02F2101/10Inorganic compounds
    • C02F2101/12Halogens or halogen-containing compounds

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Hydrology & Water Resources (AREA)
  • Engineering & Computer Science (AREA)
  • Environmental & Geological Engineering (AREA)
  • Water Supply & Treatment (AREA)
  • Birds (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a healthy skin beautifying filter material, which is prepared by coating hyaluronic acid with 10-25% of vitamin C and 10-25% of polyglutamic acid, wherein the content of hyaluronic acid is 50-80% of vitamin C, and the content of polyglutamic acid is 10-25%; the invention also discloses a preparation method of the healthy skin-beautifying filter material, which comprises the following steps: firstly, preparing 10-25% of hyaluronic acid, 50-80% of vitamin C and 10-25% of polyglutamic acid; uniformly dissolving 50-80% of vitamin C and 10-25% of polyglutamic acid in water; then, gradually adding 10% -25% of hyaluronic acid until the hyaluronic acid coats the vitamin C and the polyglutamic acid; finally, granulating, the invention has the effects of improving water quality, whitening and moisturizing.

Description

Healthy skin-beautifying filter material and preparation method thereof
Technical Field
The invention relates to the technical field of shower materials and preparation methods of the shower materials, in particular to a healthy skin-beautifying filter material and a preparation method of the healthy skin-beautifying filter material.
Background
Shower heads for bathroom in the market at present are various in forms, but a common shower head only has a basic water outlet showering function and a single function, so that the requirements of people cannot be met, and more people pay more attention to skin care along with the improvement of the consumption level of people; especially, people in the north have rough skin, acne and blackhead, are dark and easy to peel and form senile plaques; because of poor water quality and high chlorine content, hair is easy to dry and split.
The vitamin C is a substance which is easily affected by external environmental factors to lose functions, particularly easily loses functions under the condition of aqueous solution, and the invention is caused to avoid the phenomenon.
Disclosure of Invention
The invention aims to provide a healthy skin-beautifying filter material which can improve water quality, has a whitening effect and a moisturizing effect and a preparation method of the healthy skin-beautifying filter material.
In order to achieve the purpose, the technical solution of the invention is as follows:
a healthy skin beautifying filter material is prepared by coating hyaluronic acid with 10% -25% of vitamin C and 10% -25% of polyglutamic acid, wherein the content of hyaluronic acid is 50% -80% of vitamin C, and the content of polyglutamic acid is 10% -25%.
The healthy skin beautifying filter material is solid.
The healthy skin-beautifying filter material is in a fine particle state.
The healthy skin beautifying filter material is in a spindle shape with the water content lower than 1%.
The molecular weight of the hyaluronic acid is 140-200 ten thousand, and the molecular weight of the polyglutamic acid is 6-10 ten thousand.
The preparation method of the healthy skin-beautifying filter material comprises the following steps: firstly, preparing 10-25% of hyaluronic acid, 50-80% of vitamin C and 10-25% of polyglutamic acid; uniformly dissolving 50-80% of vitamin C and 10-25% of polyglutamic acid in water, wherein the weight of the water is 2-3 times that of the water; then, gradually adding 10% -25% of hyaluronic acid until the hyaluronic acid coats the vitamin C and the polyglutamic acid; and finally, granulating.
Gradually adding 10-25% hyaluronic acid until the hyaluronic acid is coated with vitamin C and polyglutamic acid, and before granulating, further comprising the following steps: then adding glycine with the content of 10% -25% and uniformly mixing.
The molecular weight of the hyaluronic acid is 140-200 ten thousand, and the molecular weight of the polyglutamic acid is 6-10 ten thousand.
The vitamin C with the content of 50% -80% and the polyglutamic acid with the content of 10% -25% are uniformly dissolved in water through stirring at the power of 500 rpm.
The granulation is carried out in a spray drying mode; the spray drying is carried out at the nozzle temperature of 110-120 ℃, the constant temperature of the cavity of 85-95 ℃ and the feeding speed of 5-10 ml/min.
After the scheme is adopted, the healthy skin beautifying filter material prepared by the preparation method of the invention utilizes hyaluronic acid to coat vitamin C and polyglutamic acid, so as to isolate the influence of external environmental factors on the vitamin C, therefore, when the shower head using the healthy skin-beautifying filter material is used, the healthy skin-beautifying filter material flows along with water flow, when the water flow flows through hyaluronic acid, the hyaluronic acid adsorbs water in advance, the water gradually permeates into the healthy skin-beautifying filter material, the vitamin C and the polyglutamic acid are slowly released, the vitamin C can remove residual chlorine in the water, the hyaluronic acid, the vitamin C and the polyglutamic acid flowing out along with the water flow can permeate into the skin, the skin is moisturized and whitened, and the polyglutamic acid also has the effect of scale inhibition, therefore, the invention has the characteristics of improving water quality, whitening and moisturizing.
Drawings
FIG. 1 is a front view of a showerhead of the present invention;
FIG. 2 is a cross-sectional view of a showerhead of the present invention;
FIG. 3 is an exploded view of the first and second chambers of the showerhead of the present invention.
[ notation ] to show
Gondola water faucet body 1
Shower handle 2
First chamber 21
A second chamber 22.
Detailed Description
To achieve the above objects and advantages, the present invention provides a novel and improved technical means and structure, which will be described in detail in connection with the preferred embodiments of the present invention.
The invention discloses a healthy skin-beautifying filter material, which has the water content of lower than 1%, specifically can be granular, can also be in an ingot state, and can also be other solid state, liquid and colloid, wherein the hyaluronic acid coats vitamin C and polyglutamic acid, the content of the hyaluronic acid is 10% -25%, the content of the vitamin C is 50% -80%, the content of the polyglutamic acid is 10% -25%, the molecular weight of the hyaluronic acid is 140-200 ten thousand, and the molecular weight of the polyglutamic acid is 6-10 ten thousand.
The invention also discloses a preparation method of the healthy skin-beautifying filter material, which comprises the following steps: firstly, preparing 10-25% of hyaluronic acid, 50-80% of vitamin C and 10-25% of polyglutamic acid; uniformly dissolving 50-80% of vitamin C and 10-25% of polyglutamic acid in water; then gradually adding 10-25% hyaluronic acid until the hyaluronic acid coats the vitamin C and the polyglutamic acid (the sustained-release life test can be performed; granulation is performed in a spray drying mode, and the detection is performed by an aqueous phase gel permeation chromatography analyzer); then adding glycine with the content of 10% -25% and uniformly mixing, so that the glycine and the high-molecular hyaluronic acid are mixed in equal proportion, and the main antioxidant has the reduction effect; finally, granulating; preferably, the molecular weight of the hyaluronic acid is 140-200 ten thousand, the molecular weight of the polyglutamic acid is 6-10 ten thousand, the water is 2-3 times of the weight of the water, the vitamin C with the content of 50-80% and the polyglutamic acid with the content of 10-25% are uniformly dissolved in the water through stirring with the power of 500rpm, granulation is carried out in a spray drying mode, and the spray drying is carried out by drying at the nozzle temperature of 110-120 ℃, the cavity constant temperature of 85-95 ℃ and the feeding speed of 5-10 ml/min.
Example one of the preparation methods of the healthy skin-beautifying filter material of the present invention
Firstly, preparing 10% of high molecular weight hyaluronic acid (also known as hyaluronic acid, the molecular weight is 140-200 ten thousand), 80% of vitamin C and 10% of low molecular weight polyglutamic acid (6-10 ten thousand), wherein the vitamin C component is fixed at 6.3 g; then, the vitamin C and the polyglutamic acid are stirred by power (500 rpm) by taking water with twice weight as a solvent until the mixture is uniform and has no concentration gradient; then gradually adding high molecular weight hyaluronic acid until the high molecular weight hyaluronic acid component is stable and correctly coats the vitamin C and the polyglutamic acid (can pass a slow release life test; granulation is carried out by using a spray drying mode, and detection is carried out by using an aqueous phase gel permeation chromatography analyzer); then adding glycine with the content of 10% and uniformly mixing, thereby utilizing the equal proportion mixing of the glycine and the high polymer hyaluronic acid and the reduction effect of the main antioxidant; finally, granulating the mixed solution by a spray drying mode (the nozzle temperature is 110 ℃, the cavity is constant in temperature and 85 ℃, and the feeding speed is 5-10 ml/min). After the healthy skin-beautifying filter material is detected by an aqueous gel permeation chromatography analyzer and a liquid chromatography analyzer, the dissolution and release speed of vitamin C can reach 7.01 +/-0.29 mg/min, the dissolution and release speed of low-molecular-weight polyglutamic acid is about 0.71 +/-0.17 mg/min, 0.57-0.62 ppm of residual chlorine (HClO) in water with the flow rate of 7L/min can be treated, and the total water flow is 7.5 tons of water.
Example two of the method of making the healthy skin filter material of the present invention
Firstly, preparing high molecular weight hyaluronic acid (also known as hyaluronic acid with the molecular weight of 140-200 ten thousand) with the content of 20%, vitamin C with the content of 50% and low molecular weight polyglutamic acid (6-10 ten thousand) with the content of 30%, wherein the vitamin C component is fixed on 6.3 g; then, the vitamin C and the polyglutamic acid are stirred by power (500 rpm) by taking water with twice weight as a solvent until the mixture is uniform and has no concentration gradient; then gradually adding high molecular weight hyaluronic acid until the high molecular weight hyaluronic acid component is stable and correctly coats the vitamin C and the polyglutamic acid; then adding glycine with the content of 10% and mixing uniformly; finally, granulating the mixed solution by a spray drying mode (the nozzle temperature is 110 ℃, the cavity is constant in temperature and 85 ℃, and the feeding speed is 5-10 ml/min). After the healthy skin-beautifying filter material is detected by an aqueous gel permeation chromatography analyzer and a liquid chromatography analyzer, the dissolution and release speed of vitamin C can reach 5.57 +/-0.35 mg/min, the dissolution and release speed of low-molecular-weight polyglutamic acid is about 3.43 +/-0.22 mg/min, 0.44-0.50 ppm of residual chlorine (HClO) in water with the flow rate of 7L/min can be treated, and the total water flow is 7.5 tons of water.
Referring to fig. 1 to 3, the invention further discloses a shower head using the healthy skin-care filter material, which includes a shower head body 1 and a shower head handle 2, wherein the shower head handle 2 is detachably and fixedly connected to the lower end of the shower head body 1, the shower head body 1 has a water outlet, a first chamber 21 accommodating the healthy skin-care filter material and a second chamber 22 accommodating the filter material are disposed in the shower head handle 2, the first chamber 21 is communicated with the water outlet of the shower head handle 2 and the second chamber 22, the second chamber 22 is disposed between the water inlet of the shower head handle 2 and the first chamber 21, and the second chamber 22 is communicated with the water inlet of the shower head handle 2.
Furthermore, the first chamber 21 and the second chamber 22 are detachably connected together, as shown in fig. 3, in the embodiment, the first chamber 21 and the second chamber 22 are connected together by a snap, but not limited thereto, the first chamber 21 and the second chamber 22 may also be connected together by a screw, so as to facilitate replacing the filtering material and adding the healthy skin-beautifying filtering material of the present invention.
In conclusion, the healthy skin-beautifying filter material prepared by the preparation method of the invention utilizes hyaluronic acid to coat vitamin C and polyglutamic acid, so as to isolate the influence of external environmental factors on vitamin C, therefore, when the shower head using the healthy skin-beautifying filter material is used, the healthy skin-beautifying filter material flows along with water flow, when the water flow flows through hyaluronic acid, the hyaluronic acid adsorbs water in advance, the water gradually permeates into the healthy skin-beautifying filter material, the vitamin C and the polyglutamic acid are slowly released, the vitamin C can remove residual chlorine in the water, the hyaluronic acid, the vitamin C and the polyglutamic acid flowing out along with the water flow can permeate into the skin, the skin is moisturized and whitened, and the polyglutamic acid also has the effect of scale inhibition, therefore, the invention has the characteristics of improving water quality, whitening and moisturizing.
While the invention has been described with reference to the foregoing embodiments, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention. Therefore, the scope of the present invention should not be limited to the embodiments disclosed, but includes various alternatives and modifications without departing from the present invention, which are encompassed by the claims.

Claims (9)

1. A healthy skin care filter material characterized by: coating 10-25% of hyaluronic acid, 50-80% of vitamin C and 10-25% of polyglutamic acid by hyaluronic acid; the healthy skin beautifying filter material is solid.
2. The healthy skin care filter material of claim 1, wherein: the healthy skin-beautifying filter material is in a fine particle state.
3. The healthy skin care filter material of claim 1, wherein: the healthy skin beautifying filter material is in a spindle shape with the water content lower than 1%.
4. The healthy skin care filter material of claim 1, wherein: the molecular weight of the hyaluronic acid is 140-200 ten thousand, and the molecular weight of the polyglutamic acid is 6-10 ten thousand.
5. A method of making a healthy skin care filter material as defined in claim 1, comprising the steps of: firstly, preparing 10-25% of hyaluronic acid, 50-80% of vitamin C and 10-25% of polyglutamic acid; uniformly dissolving 50-80% of vitamin C and 10-25% of polyglutamic acid in water, wherein the weight of the water is 2-3 times that of the water; then, gradually adding 10% -25% of hyaluronic acid until the hyaluronic acid coats the vitamin C and the polyglutamic acid; and finally, granulating.
6. The method of preparing a healthy skin care filter material of claim 5, wherein: gradually adding 10-25% hyaluronic acid until the hyaluronic acid is coated with vitamin C and polyglutamic acid, and before granulating, further comprising the following steps: then adding glycine with the content of 10% -25% and uniformly mixing.
7. The method of preparing a healthy skin care filter material of claim 5, wherein: the molecular weight of the hyaluronic acid is 140-200 ten thousand, and the molecular weight of the polyglutamic acid is 6-10 ten thousand.
8. The method of preparing a healthy skin care filter material of claim 5, wherein: the vitamin C with the content of 50% -80% and the polyglutamic acid with the content of 10% -25% are uniformly dissolved in water through stirring at the power of 500 rpm.
9. The method of preparing a healthy skin care filter material of claim 5, wherein: the granulation is carried out in a spray drying mode; the spray drying is carried out at the nozzle temperature of 110-120 ℃, the constant temperature of the cavity of 85-95 ℃ and the feeding speed of 5-10 ml/min.
CN201910354976.1A 2019-04-29 2019-04-29 Healthy skin-beautifying filter material and preparation method thereof Active CN110015703B (en)

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Publication number Priority date Publication date Assignee Title
CN110917067B (en) * 2019-12-04 2021-09-21 九牧厨卫股份有限公司 A skin caring cream with high moisture keeping effect for bath and its preparation method
CN114031198A (en) * 2021-11-17 2022-02-11 杭州耐雅德净水科技有限公司 Preparation method of skin-beautifying filter material of water purifier

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CN102869271A (en) * 2010-02-26 2013-01-09 纳瓦拉大学 Nanoparticles for the encapsulation of compounds, preparation thereof and use of same
CN204769232U (en) * 2015-06-23 2015-11-18 天之境生医科技股份有限公司 Shower nozzle with cosmetic effect
CN105836870A (en) * 2016-05-25 2016-08-10 厦门建霖工业有限公司 Household water treatment filter material capable of slowly releasing vitamin C and preparation method thereof
CN106176281A (en) * 2016-07-26 2016-12-07 西安艾尔菲生物科技有限公司 Carry the fibroin albumen/HA complex microsphere lyophilized powder of active component and preparation and application
CN107550750A (en) * 2016-06-30 2018-01-09 株式会社爱茉莉太平洋 Cosmetic composition containing different molecular weight hyaluronic acid
CN108685741A (en) * 2018-08-06 2018-10-23 广州国宇医药科技有限公司 It is a kind of promote skin barrier reparation composition and its application
CN109363966A (en) * 2018-11-02 2019-02-22 华熙福瑞达生物医药有限公司 A kind of inclusion compound containing γ-aminobutyric acid, alpha-arbutin and hyaluronic acid

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102869271A (en) * 2010-02-26 2013-01-09 纳瓦拉大学 Nanoparticles for the encapsulation of compounds, preparation thereof and use of same
CN204769232U (en) * 2015-06-23 2015-11-18 天之境生医科技股份有限公司 Shower nozzle with cosmetic effect
CN105836870A (en) * 2016-05-25 2016-08-10 厦门建霖工业有限公司 Household water treatment filter material capable of slowly releasing vitamin C and preparation method thereof
CN107550750A (en) * 2016-06-30 2018-01-09 株式会社爱茉莉太平洋 Cosmetic composition containing different molecular weight hyaluronic acid
CN106176281A (en) * 2016-07-26 2016-12-07 西安艾尔菲生物科技有限公司 Carry the fibroin albumen/HA complex microsphere lyophilized powder of active component and preparation and application
CN108685741A (en) * 2018-08-06 2018-10-23 广州国宇医药科技有限公司 It is a kind of promote skin barrier reparation composition and its application
CN109363966A (en) * 2018-11-02 2019-02-22 华熙福瑞达生物医药有限公司 A kind of inclusion compound containing γ-aminobutyric acid, alpha-arbutin and hyaluronic acid

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