CN109999359B - Device for treating male erectile dysfunction based on multi-wavelength laser - Google Patents
Device for treating male erectile dysfunction based on multi-wavelength laser Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/067—Radiation therapy using light using laser light
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0626—Monitoring, verifying, controlling systems and methods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0632—Constructional aspects of the apparatus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
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Abstract
The invention relates to a device for treating human soft tissue lesion by laser, in particular to a device for treating male erectile dysfunction based on multi-wavelength laser, which solves the problems that the average power of output laser of the existing treatment device is high and the omnibearing coverage treatment cannot be realized. The device comprises a laser power supply, a control system and an irradiation head; the irradiation head is a tubular irradiation head and/or a handheld irradiation head; a plurality of first semiconductor laser light sources which irradiate inwards are fixed on the inner surface of the tubular irradiation head; a plurality of second semiconductor laser light sources irradiating forwards are fixed on one end face of the handheld irradiation head; the laser power supply and the control system are respectively connected with the first semiconductor laser light source and/or the second semiconductor laser light source through cables, and control the single or a plurality of first semiconductor laser light sources and/or the second semiconductor laser light sources to generate pulse output and/or chopping output and/or continuously output laser; the laser wavelength of the first semiconductor laser light source and the laser wavelength of the second semiconductor laser light source are 600-1300nm, and the output power is 10-200 mW.
Description
Technical Field
The invention relates to a device for treating human soft tissue lesion by laser, in particular to a device for treating male erectile dysfunction based on multi-wavelength laser.
Background
Erectile Dysfunction (ED) is a common disease of men, not only affects the physical and psychological health of patients, but also affects the quality of life of patients, spouses and families, and the prevalence rate of ED of men of 40-70 years old is as high as about 50%. The etiological and risk factors for ED are currently thought to include age, smoking, obesity, diet and hyperlipidemia, psychosis, diabetes, cardiovascular disease, and the like. The pathophysiological basis of ED is vascular endothelial dysfunction, and the current first-line therapy for ED in the european urinary surgery society male sexual dysfunction diagnosis and treatment guidelines includes the use of phosphodiesterase type 5 (PDE5) inhibitors, which enhance the action of Nitric Oxide (NO) by inhibiting the degradation of cyclic guanosine monophosphate (cGMP) by PDE5, and thus act as a second messenger to exert a sustained action in the penile arteries and cavernous smooth muscle cells, thereby maintaining a prolonged erection of the penis. According to the low-power laser treatment theory in biophysics, terminal respiratory chain oxidase in biological cells is a light receptor with the wavelength of 600-1300nm, the cells can promote the generation of the oxidase and NO when being irradiated by light, and the cells have similar effects with PDE5 inhibitors, so that the regeneration of the cells and blood vessels is promoted, and the purpose of treating ED is achieved.
The low-energy shock wave is used for treating male erectile dysfunction, a large amount of practice is already carried out in clinic, the safety and the effectiveness are fully proved, and the method is a non-invasive operation and is expected to fundamentally repair ED pathological injury. Smooth muscle cells, endothelium, nerves, etc. of the corpus cavernosum play an important role in penile erection, and the structures of the corpus cavernosum of the ED model rat have obvious pathological injuries. Research proves that the low-energy shock waves can obviously repair the pathological damage. However, at present, the shock wave energy has the defects of uneven energy distribution and rapid energy dispersion after entering a human body, and the treatment efficiency is low.
The Chinese patent with publication number "CN 1321101A", publication date "11/7/2001", and invention name "radiation therapy apparatus for treating impotence" discloses a treatment apparatus for treating impotence by outputting laser with single wavelength through multiple optical fibers and irradiating penis with laser continuously output. The laser wavelength disclosed in this invention is between 440 and 960nm and indicates a laser power density of between 20 and 2000 milliwatts per square centimeter irradiated on the penis.
The technical solution disclosed in the above patent publication "CN 1321101A" has many drawbacks: firstly, the penis is irradiated by using a continuous output laser mode to treat impotence, and when the average power of the continuous output laser is higher (2000 milliwatts per square centimeter as described in the document), the penis soft tissue cells can be potentially damaged; at lower average powers (20 milliwatts per square centimeter as described in this document), the effective penetration depth of the laser photons is very shallow and does not produce the desired photobiological effect on the deep penile soft tissue cells. Secondly, the invention can not realize the effect of all-round covering treatment. The therapeutic apparatus can only irradiate laser to the body part of the penis, but cannot irradiate to the penis root and the penis foot part below the scrotum. It is known from anatomy that the length of the penis root and the penis crura occupies nearly 50% of the whole length of the penis, and is a necessary path for blood supply of blood vessels of the penis. Thirdly, the laser with the wavelength of 960nm-1300nm can effectively stimulate the generation of biochemical factors such as ATP, NO and the like according to the absorption condition of human soft tissues on the laser; especially, the enhancement of Nitric Oxide (NO) degrades cyclic guanosine monophosphate (cGMP), inhibits phosphodiesterase type 5 (PDE5) and achieves the aim of treating erectile dysfunction. Fourthly, the absorption depths of human soft tissues to different wavelengths are different. Because the corpus cavernosum, the penis root and the crus penis are positioned at different parts of a human body, and the subcutaneous depth of soft tissues is different according to people, the use of the laser with different wavelengths is beneficial to optimizing the effect of the laser on generating photon biology in different tissues with different depths, and the invention can not obtain the optimal curative effect only by using the laser with single wavelength. Finally, as semiconductor laser light source technology has matured, reliability and cost performance are superior to various lasers, the design of the present invention in which a single laser is coupled to multiple beams of optical fiber by optomechanical means is far less economical and practical than direct illumination using single or multiple beams of semiconductor laser.
Disclosure of Invention
The invention aims to provide a device for treating male erectile dysfunction based on multi-wavelength laser, which solves the technical problems that the conventional treatment device has high average power of output laser, cannot realize all-dimensional coverage treatment and has low cost performance, and has the advantages of low average power and all-dimensional irradiation on each part of penis.
The invention adopts the technical scheme that a device for treating male erectile dysfunction based on multi-wavelength laser is characterized in that:
comprises a laser power supply, a control system and an irradiation head; the irradiation head is a tubular irradiation head and/or a handheld irradiation head;
a plurality of first semiconductor laser light sources which irradiate inwards are fixed on the inner surface of the tubular irradiation head;
a plurality of second semiconductor laser light sources irradiating forwards are fixed on one end face of the handheld irradiation head;
the laser power supply and control system is respectively connected with the plurality of first semiconductor laser light sources and/or the plurality of second semiconductor laser light sources through cables and controls the single or the plurality of first semiconductor laser light sources and/or the plurality of second semiconductor laser light sources to generate pulse output and/or chopping output and/or continuously output laser;
the laser wavelengths of the first semiconductor laser light source and the second semiconductor laser light source are both within the range of 600-1300nm, and the output powers are both within the range of 10-200 mW;
the output laser wavelengths of the plurality of first semiconductor laser light sources and/or the plurality of second semiconductor laser light sources are at least two or more.
Further, the device also comprises a foot switch;
the foot switch is connected with the laser power supply and the control system through a connecting wire and is used for controlling the laser output time.
Further, the first semiconductor laser light source and the second semiconductor laser light source are arranged in a transparent silica gel film, a transparent heat conducting gel film or a transparent polyurethane film;
the plurality of first semiconductor laser light sources are fixed on a copper or aluminum metal cylinder;
the plurality of second semiconductor laser light sources are fixed on a copper or aluminum metal member.
Further, the first semiconductor laser light source and the second semiconductor laser light source are both laser diodes.
Further, the laser diode is a side cavity emitting ordinary semiconductor laser diode or a vertical cavity emitting semiconductor laser diode.
Furthermore, the frequency of the laser is adjustable within 0.1Hz-1kHz, the pulse width is adjustable within 1ms-10s, the peak power of the laser is adjustable within 0-15W, and the average power is not more than 5W;
the laser has two or more wavelengths of 650nm, 750nm, 790nm, 808nm, 810nm, 940nm and 980 nm.
Further, a laser-free band with the width of 1-2cm is axially arranged in the tubular irradiation head.
Further, the laser power supply and control system comprises a master control single chip microcomputer, a constant current/constant voltage controller and a semiconductor laser power supply which are connected in sequence;
the semiconductor laser power supply is respectively connected with the plurality of first semiconductor laser light sources and the plurality of second semiconductor laser light sources through cables.
Furthermore, the laser power supply and control system also comprises a human-computer interaction interface;
the human-computer interaction interface is connected with the master control single chip microcomputer.
Further, the semiconductor laser power supply is a direct current power supply; the human-computer interaction interface is a capacitive touch screen or a resistive touch screen.
The invention has the beneficial effects that:
1. the invention adopts 600-1300nm laser as the laser treatment wavelength, thereby improving the capability of treating male erectile dysfunction.
2. The laser adopted by the invention can be directly irradiated under higher pulse peak power. Because the average power is lower, the heat effect can not be generated to the human body, so that the treatment effect is safe, effective, convenient and comfortable. And the light source control host is small in size, convenient to move and carry and beneficial to practical application.
3. The invention adopts the combination of the tubular irradiation head and the hand-held irradiation head, can irradiate all parts of the penis in all directions, and avoids the defect that the penis root and the crus of the penis can not be irradiated in the prior art.
4. In order to avoid laser irradiation on the urethra part of the penis, the tubular irradiation head is internally provided with a laser-free belt.
5. The invention uses semiconductor laser light source, is economical and practical, has the service life of more than 1 ten thousand hours, and has stable and reliable whole system and long product service life.
Drawings
FIG. 1 is a schematic diagram of an embodiment of the present invention;
FIG. 2 is a schematic diagram of the internal connection of the laser power supply and control system and the connection with the external semiconductor laser light source according to the embodiment of the present invention;
FIG. 3 is a line of light absorption by water and hemoglobin;
FIG. 4 is a schematic diagram of a laser pulse sequence when a pulse output mode is adopted as a laser output mode in an embodiment of the present invention;
fig. 5 is a schematic diagram of a laser pulse sequence when the laser output mode adopts the chopper output mode in the embodiment of the present invention.
The reference numerals in the drawings are explained as follows:
1-a laser power supply and control system, 11-a main control singlechip, 12-a constant current/constant voltage controller, 13-a semiconductor laser power supply, 14-a man-machine interaction interface, 21-a tubular irradiation head, 211-a first semiconductor laser light source, 22-a handheld irradiation head, 221-a second semiconductor laser light source and 3-a foot switch.
Detailed Description
The present invention will be described in detail below with reference to the accompanying drawings and specific embodiments.
Referring to fig. 1, the device for treating male erectile dysfunction based on multi-wavelength laser of the present invention structurally comprises a laser power supply and control system 1 and an irradiation head; the irradiation head is a tubular irradiation head 21 and/or a handheld irradiation head 22; a plurality of first semiconductor laser light sources 211 irradiating inwards are fixed on the inner surface of the tubular irradiating head 21; the first semiconductor laser light sources 211 are disposed in a transparent silica gel, a transparent heat-conducting gel, or a transparent polyurethane film, and the plurality of first semiconductor laser light sources 211 in the tubular irradiation head 21 are fixed to a metal mechanical device capable of dissipating heat, and irradiate laser beams into a tubular shape. A plurality of second semiconductor laser light sources 221 irradiating forwards are fixed on one end face of the handheld irradiation head 22, and a laser light outlet can be a layer of transparent silica gel, air or other window for allowing light with the wavelength of 600-1300nm to pass through; the second semiconductor laser light sources 221 are disposed in a transparent silica gel, a transparent heat-conducting gel, or a transparent polyurethane film, and the plurality of second semiconductor laser light sources 221 in the handheld irradiation head 22 are fixed on a metal mechanical device capable of dissipating heat, and irradiate laser beams to the outside of the handheld irradiation head 22. The laser power supply and control system 1 is respectively connected with the plurality of first semiconductor laser light sources 211 and/or the plurality of second semiconductor laser light sources 221 through cables, and controls the single or the plurality of first semiconductor laser light sources 211 and/or the plurality of second semiconductor laser light sources 221 to generate pulse output and/or chopping output and/or continuous output laser, and the laser power of the laser power can be adjusted. The laser wavelengths of the first semiconductor laser light source 211 and the second semiconductor laser light source 221 are both within the range of 600-1300nm, and the laser wavelengths output by the plurality of first semiconductor laser light sources 211 and/or the plurality of second semiconductor laser light sources 221 are at least two or more, specifically, two or more of 650nm, 750nm, 790nm, 808nm, 810nm, 940nm and 980nm can be adopted. The output powers of the first semiconductor laser light source 211 and the second semiconductor laser light source 221 are both in the range of 10-200 mW.
For effective heat dissipation, in the present embodiment, the plurality of first semiconductor laser light sources 211 are fixed on the copper or aluminum metal cylinder by welding or pressing; the plurality of second semiconductor laser light sources 221 are fixed to a copper or aluminum metal member by welding or pressing.
In this embodiment, the first semiconductor laser light source 211 and the second semiconductor laser light source 221 are both laser diodes, specifically, side-cavity light emitting ordinary semiconductor laser diodes or vertical-cavity (VCSEL) light emitting semiconductor laser diodes.
The frequency of the laser is adjustable between 0.1Hz and 1kHz, the pulse width is adjustable between 1ms and 10s, the peak power of the laser is adjustable between 0W and 15W, and the average power is not more than 5W.
In order to avoid the laser light from irradiating the urethra region of the penis, the distribution of the first semiconductor laser light source 211 in the tubular irradiation head 21 may be non-uniform, for example, a laser-free zone 1-2cm wide is axially disposed in the tubular irradiation head 21. When in use, the urethra part of the penis can be placed on the laser-free belt. In order to adapt to different irradiated bodies, another design is that the distribution of the first semiconductor laser light source 211 in the tubular irradiation head 21 is uniform. During treatment, a reflective adhesive tape with the width of about 1cm can be attached to the penis along the penis urethra, or a shading plate is used for blocking the first semiconductor laser light source 211 so as to prevent laser from irradiating the penis urethra tissue.
Referring to fig. 2, the laser power supply and control system 1 includes a human-computer interaction interface 14, and a master control single chip 11, a constant current/constant voltage controller 12, and a semiconductor laser power supply 13 connected in sequence; the semiconductor laser power supply 13 is connected to the plurality of first semiconductor laser light sources 211 and the plurality of second semiconductor laser light sources 221 through cables, respectively. The man-machine interaction interface 14 is connected with the main control singlechip 11. Through the human-machine interface 14, a user can conveniently control the laser output characteristics of the first semiconductor laser light source 211 and the second semiconductor laser light source 221, such as a specific laser wavelength, laser output power or laser output waveform. The semiconductor laser power supply 13 is a dc power supply; the human-computer interaction interface 14 is a capacitive touch screen or a resistive touch screen. The semiconductor laser power supply 13 controls the single or multiple first semiconductor laser light sources 211 and/or second semiconductor laser light sources 221 under the control of the main control single chip microcomputer 11, and enables the single or multiple first semiconductor laser light sources 211 and/or second semiconductor laser light sources 221 to generate pulse output and/or chopping output and/or continuous output or close laser output of the single or multiple second semiconductor laser light sources. Therefore, the laser beams with different wavelengths and different irradiation positions can be controlled as required.
In order to control the laser output conveniently, the laser output in the invention can set parameters including irradiation mode, laser wavelength, laser output power and the like according to clinical needs, including presetting irradiation time, or controlling the laser output time at any time through the foot switch 3. The foot switch 3 is connected with the laser power supply and control system 1 through a connecting wire.
The principle of the invention is as follows: human soft tissues absorb light to a certain extent, and the absorption rates of water and hemoglobin to light with different wavelengths are different. Photon biology is generated when photons are absorbed by soft tissue. FIG. 3 shows the light absorption lines of water and hemoglobin, wherein the wavelength band is 600-1300nm within two vertical lines. The characteristic of this band is that light has low absorption characteristics for hemoglobin and water, and thus can be transmitted deeper in tissue, which is advantageous for deep level tissue treatment. This band is also referred to as the clinical window. The terminal respiratory chain oxidase in the biological cell is a photoreceptor with the wavelength of 600-1300nm, the cells can promote the generation of the oxidase and NO by illumination, so as to promote the regeneration of cells, nerves and blood vessels, and the physiological mechanism of penile erection can be improved by multiple non-invasive irradiation, thereby achieving the purpose of effectively treating male Erectile Dysfunction (ED).
Because of different wavelengths, the penetration depth of tissues is also different, and the laser with the wavelength of 600-1300nm is used for improving local blood circulation, promoting neoangiogenesis and treating male pre-erectile dysfunction through NO generation. In order to further enhance the photon biological effect, the present embodiment adopts a pulsed or chopped laser output mode, see fig. 4 and 5, and these two laser output modes are characterized in that under the condition of low average power of laser, higher peak power can be obtained, and the photon biological effect is characterized in that the lower average power does not generate excessive heat to the irradiated soft tissue to damage the soft tissue, and at the same time, the higher peak power can enable enough photons to reach deeper soft tissue, such as the lower part of the corpus cavernosum, the penis root and the deep layer part of the penis foot. E.g. at an average power density of 50mW/cm2In the case of (1%), a duty ratio of 5000mW/cm can be obtained2The peak power density of (a). Sufficient photons still have the required photon biological effect on the lower tissue of the cavernous body of the penis after the scattering and the absorption of skin, water, blood and the upper soft tissue of the cavernous body of the penis. In a pulse or chopping working state, a user can set the repetition frequency, the pulse width and the laser peak power of the laser output according to requirements. The laser frequency of the embodiment is adjustable within 0.1Hz-1kHz, the pulse width is adjustable within 1ms-10s, and the laser peak power is adjustable within 0-15W. When the system is in operation, makeThe user can preset the irradiation time according to the clinical requirement, or control the laser output time at any time through the foot switch 3. As shown in FIGS. 4 and 5, t0-t1 and t2-t3 are normal light emission, and t1-t2 are stop light emission. The laser light is not output when the light emission is stopped.
In order to treat the shaft of the penis and the root of the penis and crus penis located below the scrotum simultaneously, the irradiation head of this embodiment has two, a tubular irradiation head 21 in which the shaft of the penis is placed, and a hand-held irradiation head 22. The multi-wavelength laser in the tubular irradiation head 21 is irradiated inwards to the penis body; the laser light in the hand-held illumination head 22 illuminates the shaft of the penis, the base of the penis and the crus of the penis manually.
The mechanism of the invention is that the low-power density laser with different wavelengths irradiates the biological tissue in the penis in a pulse mode, a chopping mode, a continuous mode or a combined mode of the three modes to promote the generation of NO, achieve the biostimulation effect of the laser on the cells in the penis, promote the nerve repair and the blood vessel regeneration and achieve the aim of treating ED.
The working process of the invention is as follows:
the laser with the wavelength of 600-1300nm is used for directly irradiating the surface of the human tissue, and the laser energy is scattered and transmitted to the human penis tissue for the treatment of erectile dysfunction.
The characteristic that 600-1300nm laser can be absorbed by the deep layer of human tissue is utilized to irradiate the human pathological change soft tissue, the laser promotes the cell growth, the nerve cell growth, the vascular proliferation and the NO synthesis increase, the organ function recovery is guided, and the male erectile dysfunction is treated.
The laser irradiated on the tissue surface can be output by Continuous Wave (CW), or pulse wave, chopped wave, continuous output or combination of these output modes, the pulse width is adjustable from 1ms to 10s, and the pulse frequency is adjustable from 0.1Hz to 1 kHz. The laser output energy is adjustable, and the upper limit is that soft tissues are not damaged.
The laser irradiated on the tissue surface can be fixed dose, fixed program output specific dose, or the user sets the laser parameters according to the clinical requirement and adjusts the irradiation time through the foot switch 3 to treat the patient.
Claims (9)
1. A device for treating male erectile dysfunction based on multi-wavelength laser is characterized in that:
comprises a laser power supply and control system (1) and an irradiation head; the irradiation head is a tubular irradiation head (21) and/or a handheld irradiation head (22);
a plurality of first semiconductor laser light sources (211) irradiating inwards are fixed on the inner surface of the tubular irradiation head (21);
a plurality of second semiconductor laser light sources (221) irradiating forwards are fixed on one end face of the handheld irradiating head (22);
the first semiconductor laser light source (211) and the second semiconductor laser light source (221) are arranged in a transparent silica gel film, a transparent heat-conducting gel film or a transparent polyurethane film;
a plurality of the first semiconductor laser light sources (211) are fixed on a copper or aluminum metal cylinder;
a plurality of second semiconductor laser light sources (221) are fixed on a copper or aluminum metal member;
the laser power supply and control system (1) is respectively connected with the plurality of first semiconductor laser light sources (211) and/or the plurality of second semiconductor laser light sources (221) through cables and controls the single or the plurality of first semiconductor laser light sources (211) and/or the plurality of second semiconductor laser light sources (221) to generate pulse output and/or chopping output and/or continuous output laser;
the laser wavelengths of the first semiconductor laser light source (211) and the second semiconductor laser light source (221) are both in the range of 600-1300nm, and the output powers are both in the range of 10-200 mW;
the plurality of first semiconductor laser light sources (211) and/or the plurality of second semiconductor laser light sources (221) output at least two or more laser wavelengths.
2. The device for treating male erectile dysfunction based on the multi-wavelength laser according to claim 1, wherein:
also comprises a foot switch (3);
the foot switch (3) is connected with the laser power supply and control system (1) through a connecting wire and is used for controlling the laser output time.
3. The device for treating male erectile dysfunction based on the multi-wavelength laser according to claim 2, wherein: the first semiconductor laser light source (211) and the second semiconductor laser light source (221) are both laser diodes.
4. The device for treating male erectile dysfunction based on the multi-wavelength laser according to claim 3, wherein: the laser diode is a side-cavity emitting common semiconductor laser diode or a vertical-cavity emitting semiconductor laser diode.
5. The device for treating male erectile dysfunction based on the multi-wavelength laser according to claim 3, wherein:
the frequency of the laser is adjustable within 0.1Hz-1kHz, the pulse width is adjustable within 1ms-10s, the peak power of the laser is adjustable within 0-15W, and the average power is not more than 5W;
the laser has two or more wavelengths of 650nm, 750nm, 790nm, 808nm, 810nm, 940nm and 980 nm.
6. The device for treating male erectile dysfunction based on the multi-wavelength laser according to claim 2, wherein: a laser-free belt with the width of 1-2cm is axially arranged in the tubular irradiation head (21).
7. The device for treating male erectile dysfunction based on the multi-wavelength laser according to claim 2, wherein:
the laser power supply and control system (1) comprises a master control single chip microcomputer (11), a constant current/constant voltage controller (12) and a semiconductor laser power supply (13) which are connected in sequence;
the semiconductor laser power supply (13) is connected to the plurality of first semiconductor laser light sources (211) and the plurality of second semiconductor laser light sources (221) via cables, respectively.
8. The device for treating male erectile dysfunction based on the multi-wavelength laser according to claim 7, wherein:
the laser power supply and control system (1) further comprises a human-computer interaction interface (14);
the human-computer interaction interface (14) is connected with the master control singlechip (11).
9. The device for treating male erectile dysfunction based on the multi-wavelength laser according to claim 8, wherein: the semiconductor laser power supply (13) is a direct current power supply; the human-computer interaction interface (14) is a capacitive touch screen or a resistive touch screen.
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| CN111146676B (en) * | 2019-12-30 | 2021-07-06 | 武汉戴美激光科技有限公司 | Method and equipment for generating multi-wavelength pulse laser |
| CN112546453B (en) * | 2020-10-15 | 2022-11-29 | 西安蓝极医疗电子科技有限公司 | Luminous body component and device for treating male erectile dysfunction based on laser irradiation |
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