CN109846604B - Intelligent sanitary pad and preparation method thereof - Google Patents

Intelligent sanitary pad and preparation method thereof Download PDF

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CN109846604B
CN109846604B CN201910182626.1A CN201910182626A CN109846604B CN 109846604 B CN109846604 B CN 109846604B CN 201910182626 A CN201910182626 A CN 201910182626A CN 109846604 B CN109846604 B CN 109846604B
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chip
sanitary pad
ase
concentration
solution
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CN109846604A (en
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曹维
俞励平
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GUANGZHOU ZHONGSHAN UNIVERSITY DRUG DEVELOPMENT Co.,Ltd.
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Guangzhou Zhongshan University Drug Development Co ltd
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Abstract

The invention discloses a preparation method of an intelligent sanitary pad, which is characterized by comprising the following steps: step one, manufacturing an ASE-1 chip; and step two, embedding the manufactured ASE-1 chip into the sanitary pad to obtain the intelligent sanitary pad. The invention also discloses an intelligent sanitary pad, which comprises a sanitary pad body (1) and an ASE-1 chip (2) arranged on the sanitary pad body. When the intelligent sanitary pad is used, the intelligent sanitary pad is attached to underpants, when the healthy leucorrhea of the female genital tract is normal, the leucorrhea is contacted with the ASE-1 chip, and the ASE-1 chip does not change color; when the pathological leucorrhea of the female genital tract is abnormal, the abnormal leucorrhea contacts the ASE-1 chip, and the ASE-1 chip changes color to prompt a female wearer to go to a hospital for gynecological examination; the invention is simple to use, and the user can carry out initial examination on the bacterial vaginal disease by himself, thereby preventing the user from delaying the treatment time caused by no discovery after the disease appears.

Description

Intelligent sanitary pad and preparation method thereof
Technical Field
The invention relates to a functional protection pad, in particular to an intelligent sanitary protection pad and a preparation method thereof.
Background
Bacterial vaginal disease is one of the most common diseases in gynecology and obstetrics, and relevant clinical statistics show that the positive rate of vaginitis in gynecological census is about 15-38%, so that the vaginitis is easy to recur, not all patients can show obvious symptoms, and many patients cannot pay enough attention in the initial stage of inflammation, so that the treatment time is delayed. Therefore, it is very important to research a means for the patient to perform the preliminary examination of bacterial vaginal diseases.
Disclosure of Invention
The invention aims to overcome the defects and provides an intelligent sanitary pad which can be used for female to automatically carry out initial examination on bacterial vaginosis per se in daily life and a preparation method thereof.
The purpose of the invention is realized by the following technical scheme: a preparation method of an intelligent sanitary pad comprises the following steps:
step one, manufacturing an ASE-1 chip;
step two, embedding the manufactured ASE-1 chip into a sanitary pad to obtain an intelligent sanitary pad;
the manufacturing of the ASE-1 chip in the first step comprises the following steps:
(1) manufacturing a chip carrier;
(2) bottom color is applied to the chip carrier; soaking the chip carrier in an acid bright yellow dye, adding an auxiliary agent, and dip-dyeing in an environment at a temperature of 45-80 ℃; centrifuging the dip-dyed chip carrier, and drying at 50-60 ℃ to obtain a chip body;
(3) preparing a dye; dissolving a coloring agent in an alcohol solution with the concentration of 60-75%, adding a povidone-iodine solution, a polyethylene glycol solution, a gelatin solution and a gum arabic solution, adjusting the pH value to 5-6, and filtering to obtain a dye;
(4) manufacturing an ASE-1 chip; and (3) spraying a dye on the chip body prepared in the step (2), and airing to obtain the ASE-1 chip.
Further, the chip carrier material is cleaned, dried and cut in the step (1) to obtain a chip carrier; the chip carrier material is one of cotton cloth, non-woven fabric and paper.
The dip-dyeing time in the step (2) is 5-10 minutes, and the concentration of the acid light yellow dye is 0.2-1.0%; the auxiliary agent is dilute hydrochloric acid or phosphoric acid or acetic acid, and the concentration of the auxiliary agent is 0.5-10%.
The concentration of the povidone-iodine solution added in the step (3) is 0.05-0.5%, the concentration of the polyethylene glycol solution is 1.0-5.0%, the concentration of the gelatin solution is 0.2-2.0%, and the concentration of the gum arabic solution is 0.2-2.0%.
And (4) filtering by using a 300-mesh filter screen in the step (3).
The coloring agent in the step (3) is an acid coloring agent or a neutral coloring agent or a basic coloring agent; the acid coloring agent is one of congo red, erythrosine and aniline black, the neutral coloring agent is eosin or methylene blue, and the alkaline coloring agent is one of alkaline compound red, neutral red, malachite green, safranin, crystal violet and methyl violet.
An intelligent sanitary pad comprises a sanitary pad body and an ASE-1 chip arranged on the sanitary pad body.
Compared with the prior art, the invention has the following advantages and beneficial effects: when the intelligent sanitary pad is used, the intelligent sanitary pad is attached to underpants, when the healthy leucorrhea of the female genital tract is normal, the leucorrhea is contacted with the ASE-1 chip, and the ASE-1 chip does not change color; when the pathological leucorrhea of the female genital tract is abnormal, the abnormal leucorrhea contacts the ASE-1 chip, and the ASE-1 chip changes color to prompt a female wearer to go to a hospital for gynecological examination; the invention is simple to use, and the user can carry out initial examination on the bacterial vaginal disease by himself, thereby preventing the user from delaying the treatment time caused by no discovery after the disease appears.
Drawings
Fig. 1 is a structural view of the intelligent sanitary pad of the present invention.
The reference numbers of the above figures refer to: 1-sanitary pad body, 2-ASE-1 chip.
Detailed Description
The present invention will be described in further detail with reference to examples, but the embodiments of the present invention are not limited thereto.
Example 1
The preparation method of the intelligent sanitary pad of the embodiment comprises the following steps:
step one, manufacturing an ASE-1 chip; the method specifically comprises the following steps:
(1) manufacturing a chip carrier; cleaning, airing and cutting the chip carrier material to obtain a chip carrier; chip carrier material is one of cotton, non-woven fabrics, paper, and 45 ~ 55 gsm's water thorn glues non-woven fabrics entirely as chip carrier material is selected for use to this embodiment.
(2) Bottom color is applied to the chip carrier; soaking a chip carrier in an acid bright yellow dye, adding 2% dilute hydrochloric acid as an auxiliary agent to stabilize the proton concentration, and dip-dyeing in an environment at 45 ℃; centrifuging the dip-dyed chip carrier, and drying at 50 ℃ to obtain a chip body; wherein the concentration of the acid bright yellow dye is 0.2 percent, and the dip dyeing time is 5 minutes.
(3) Preparing a dye; dissolving the staining agent in 60% alcohol solution, and adding povidone iodine solution, polyethylene glycol solution, gelatin solution and acacia gum solution to make thallus adhere, thallus protein denature and color; meanwhile, regulating the pH value to be 5, and filtering by adopting a 300-mesh filter screen to obtain a dye; the coloring agent used in this example was crystal violet, the added povidone-iodine solution had a concentration of 0.05%, the polyethylene glycol solution had a concentration of 1.0%, the gelatin solution had a concentration of 0.2%, and the gum arabic solution had a concentration of 0.2%.
(4) Manufacturing an ASE-1 chip; and (3) spraying a dye on the chip body prepared in the step (2), and airing to obtain the ASE-1 chip.
And step two, embedding the manufactured ASE-1 chip into the sanitary pad to obtain the intelligent sanitary pad. In the embodiment, a traditional sanitary pad is adopted, and the ASE-1 chip is embedded below the surface layer of the sanitary pad or sewn on the surface of the sanitary pad by using sewing threads.
In the intelligent sanitary pad prepared by the embodiment, dilute hydrochloric acid is added into the ASE-1 chip as an auxiliary agent, and when the concentration of protons in the leucorrhea is high, the ASE-1 chip keeps yellow and stable; when the hydroxyl ions in the white band are high, the hydroxyl ions and protons are combined into water, the concentration of the protons is reduced and is not enough to stabilize yellow groups in the ASE-1 chip, at the moment, red groups are exposed, and the chip is mauve.
The intelligent sanitary pad prepared by the embodiment is used by women in non-menstrual period, the intelligent sanitary pad is stuck on underpants when in use, and when the vagina of a user is clean and the reproductive system is healthy, the ASE-1 chip is yellow. When the female reproductive system is unhealthy, the vaginal cleanliness is reduced, pathogenic bacteria are propagated, lactic acid bacteria in the leucorrhea are reduced, the proton concentration is obviously reduced, hydroxide ions are increased, a large amount of protons in the ASE-1 chip are neutralized, the yellow system in the ASE-1 chip cannot be stable, and then the yellow system is converted into mauve, so that the vaginal cleanliness is reduced, and the reproductive health of the female is prompted to be in a problem.
Example 2
The preparation method of the intelligent sanitary pad of the embodiment comprises the following steps:
step one, manufacturing an ASE-1 chip; the method specifically comprises the following steps:
(1) manufacturing a chip carrier; cleaning, airing and cutting the chip carrier material to obtain a chip carrier; the chip carrier material is one of cotton cloth, non-woven fabrics, paper, and the cotton cloth is selected as the chip carrier material for this embodiment.
(2) Bottom color is applied to the chip carrier; soaking a chip carrier in acid bright yellow dye, adding 5% phosphoric acid as an auxiliary agent to stabilize the proton concentration, and dip-dyeing at 60 ℃; centrifuging the impregnated chip carrier, and drying at 55 ℃ to obtain a chip body; wherein the concentration of the acid bright yellow dye is 0.5 percent, and the dip dyeing time is 8 minutes.
(3) Preparing a dye; dissolving the staining agent in 70% alcohol solution, and adding povidone iodine solution, polyethylene glycol solution, gelatin solution and acacia gum solution to make thallus adhere, thallus protein denature and color; meanwhile, regulating the pH value to 5.5, and filtering by adopting a 300-mesh filter screen to obtain a dye; the staining agent used in this example was methylene blue, the concentration of the added povidone-iodine solution was 0.25%, the concentration of the polyethylene glycol solution was 2.5%, the concentration of the gelatin solution was 1.0%, and the concentration of the gum arabic solution was 1.0%.
(4) Manufacturing an ASE-1 chip; and (3) spraying a dye on the chip body prepared in the step (2), and airing to obtain the ASE-1 chip.
And step two, embedding the manufactured ASE-1 chip into the sanitary pad to obtain the intelligent sanitary pad. In the embodiment, a traditional sanitary pad is adopted, and the ASE-1 chip is embedded below the surface layer of the sanitary pad or sewn on the surface of the sanitary pad by using sewing threads.
Phosphoric acid is added into the ASE-1 chip in the intelligent sanitary pad prepared by the embodiment to serve as an auxiliary agent, and when the concentration of protons in a white band is high, the ASE-1 chip keeps yellow and stable; when the hydroxyl ions in the white band are high, the hydroxyl ions and protons are combined into water, the concentration of the protons is reduced and is not enough to stabilize yellow groups in the ASE-1 chip, at the moment, red groups are exposed, and the chip is mauve.
The intelligent sanitary pad prepared by the embodiment is used by women in non-menstrual period, the intelligent sanitary pad is stuck on underpants when in use, and when the vagina of a user is clean and the reproductive system is healthy, the ASE-1 chip is yellow. When the female reproductive system is unhealthy, the vaginal cleanliness is reduced, pathogenic bacteria are propagated, lactic acid bacteria in the leucorrhea are reduced, the proton concentration is obviously reduced, hydroxide ions are increased, a large amount of protons in the ASE-1 chip are neutralized, the yellow system in the ASE-1 chip cannot be stable, and then the yellow system is converted into mauve, so that the vaginal cleanliness is reduced, and the reproductive health of the female is prompted to be in a problem.
Example 3
The preparation method of the intelligent sanitary pad of the embodiment comprises the following steps:
step one, manufacturing an ASE-1 chip; the method specifically comprises the following steps:
(1) manufacturing a chip carrier; cleaning, airing and cutting the chip carrier material to obtain a chip carrier; the chip carrier material is one of cotton cloth, non-woven fabrics, paper, and the paper is selected for use as chip carrier material to this embodiment.
(2) Bottom color is applied to the chip carrier; soaking a chip carrier in an acid bright yellow dye, adding acetic acid with the concentration of 10% as an auxiliary agent to stabilize the proton concentration, and dip-dyeing in an environment of 80 ℃; centrifuging the impregnated chip carrier, and drying at 60 ℃ to obtain a chip body; wherein the concentration of the acid bright yellow dye is 1.0 percent, and the dip dyeing time is 10 minutes.
(3) Preparing a dye; dissolving the staining agent in 75% alcohol solution, and adding povidone iodine solution, polyethylene glycol solution, gelatin solution and acacia gum solution to make thallus adhere, thallus protein denature and color; meanwhile, regulating the pH value to be 6, and filtering by adopting a 300-mesh filter screen to obtain a dye; the coloring agent used in this example is congo red, the concentration of the added povidone-iodine solution is 0.5%, the concentration of the polyethylene glycol solution is 5.0%, the concentration of the gelatin solution is 2.0%, and the concentration of the gum arabic solution is 2.0%.
(4) Manufacturing an ASE-1 chip; and (3) spraying a dye on the chip body prepared in the step (2), and airing to obtain the ASE-1 chip.
And step two, embedding the manufactured ASE-1 chip into the sanitary pad to obtain the intelligent sanitary pad. In the embodiment, a traditional sanitary pad is adopted, and the ASE-1 chip is embedded below the surface layer of the sanitary pad or sewn on the surface of the sanitary pad by using sewing threads.
In the intelligent sanitary pad prepared by the embodiment, acetic acid is added into the ASE-1 chip as an auxiliary agent, and when the concentration of protons in the leucorrhea is high, the ASE-1 chip keeps yellow and stable; when the hydroxyl ions in the white band are high, the hydroxyl ions and protons are combined into water, the concentration of the protons is reduced and is not enough to stabilize yellow groups in the ASE-1 chip, at the moment, red groups are exposed, and the chip is mauve.
The intelligent sanitary pad prepared by the embodiment is used by women in non-menstrual period, the intelligent sanitary pad is stuck on underpants when in use, and when the vagina of a user is clean and the reproductive system is healthy, the ASE-1 chip is yellow. When the female reproductive system is unhealthy, the vaginal cleanliness is reduced, pathogenic bacteria are propagated, lactic acid bacteria in the leucorrhea are reduced, the proton concentration is obviously reduced, hydroxide ions are increased, a large amount of protons in the ASE-1 chip are neutralized, the yellow system in the ASE-1 chip cannot be stable, and then the yellow system is converted into mauve, so that the vaginal cleanliness is reduced, and the reproductive health of the female is prompted to be in a problem.
Inviting 55 female volunteers to test the intelligent sanitary pad prepared by the method of the above examples 1-3; among 55 female volunteers, 9 cases were reproductive and healthy, 12 cases were diagnosed with mycotic vaginitis, and 34 cases were diagnosed with bacterial vaginitis, and the test structures are as shown in table one:
detecting the number of women who have healthy reproduction The number of patients with mycotic vaginitis is detected The number of patients with bacterial vaginitis is detected
Example 1 9 10 22
Example 2 9 11 24
Example 3 9 10 23
Watch 1
As shown in the table I, the rate of false positive of the intelligent sanitary pad prepared by the method of examples 1-3 is 0; the detection rate of the mycotic vaginitis reaches more than 83 percent, and the detection rate of the mycotic vaginitis in the embodiment 2 is the highest; the detection rate of the bacterial vaginitis reaches over 64 percent, and the detection rate of the bacterial vaginitis in example 2 is the highest.
Example 4
This embodiment is an intelligent sanitary pad prepared by any one of the preparation methods of embodiments 1 to 3, and as shown in fig. 1, the intelligent sanitary pad comprises a sanitary pad body 1 and an ASE-1 chip 2 disposed on the sanitary pad body. The sanitary pad adopts a traditional sanitary pad, and the ASE-1 chip is embedded below the surface layer of the sanitary pad or is sewn on the surface of the sanitary pad by adopting sewing threads.
As described above, the present invention can be preferably realized.

Claims (4)

1. A preparation method of an intelligent sanitary pad is characterized by comprising the following steps:
step one, manufacturing an ASE-1 chip;
step two, embedding the manufactured ASE-1 chip into a sanitary pad to obtain an intelligent sanitary pad;
the manufacturing of the ASE-1 chip in the first step comprises the following steps:
(1) manufacturing a chip carrier;
(2) bottom color is applied to the chip carrier; soaking the chip carrier in an acid bright yellow dye, adding an auxiliary agent, and dip-dyeing in an environment at the temperature of 45-80 ℃; centrifuging the dip-dyed chip carrier, and drying at 50-60 ℃ to obtain a chip body;
(3) preparing a dye; dissolving a coloring agent in an alcohol solution with the concentration of 60-75%, adding a povidone-iodine solution, a polyethylene glycol solution, a gelatin solution and a gum arabic solution, adjusting the pH value to 5-6, and filtering to obtain a dye;
(4) manufacturing an ASE-1 chip; spraying a dye on the chip body prepared in the step (2), and airing to obtain an ASE-1 chip;
the dip-dyeing time in the step (2) is 5-10 minutes, and the concentration of the acid light yellow dye is 0.2-1.0%; the auxiliary agent is dilute hydrochloric acid or phosphoric acid or acetic acid, and the concentration of the auxiliary agent is 0.5-10%; the concentration of the povidone-iodine solution added in the step (3) is 0.05-0.5%, the concentration of the polyethylene glycol solution is 1.0-5.0%, the concentration of the gelatin solution is 0.2-2.0%, and the concentration of the gum arabic solution is 0.2-2.0%; the coloring agent in the step (3) is an acid coloring agent or a neutral coloring agent or a basic coloring agent; the acid coloring agent is one of congo red, erythrosine and aniline black, the neutral coloring agent is eosin or methylene blue, and the alkaline coloring agent is one of alkaline compound red, neutral red, malachite green, safranin, crystal violet and methyl violet.
2. The method for preparing an intelligent sanitary pad according to claim 1, wherein the chip carrier material is cleaned, dried and cut in step (1) to obtain a chip carrier; the chip carrier material is one of cotton cloth, non-woven fabric and paper.
3. The method for preparing an intelligent sanitary pad as claimed in claim 1, wherein the filtering in step (3) is performed by using a 300-mesh filtering net.
4. An intelligent sanitary pad prepared by the method for preparing an intelligent sanitary pad according to any one of claims 1 to 3, comprising a sanitary pad body (1) and an ASE-1 chip (2) disposed on the sanitary pad body.
CN201910182626.1A 2019-03-12 2019-03-12 Intelligent sanitary pad and preparation method thereof Active CN109846604B (en)

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Publication number Priority date Publication date Assignee Title
CN111134965A (en) * 2019-12-30 2020-05-12 福建恒安集团有限公司 Preparation method of intelligent sanitary product

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005152840A (en) * 2003-11-27 2005-06-16 Research Institute Of Innovative Technology For The Earth Method of producing water-absorbing material
CN201189241Y (en) * 2008-03-17 2009-02-04 陈潇 Sanitary towel with health-care function
CN101484142A (en) * 2006-03-24 2009-07-15 奥克思利尤姆国际控股公司 Stabilized compositions containing alkaline labile drugs
CN104510573A (en) * 2013-10-08 2015-04-15 李建安 Sanitary pad for health observation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030015003A1 (en) * 2001-03-28 2003-01-23 Fisler Diana Kim Low temperature glass for insulation fiber

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005152840A (en) * 2003-11-27 2005-06-16 Research Institute Of Innovative Technology For The Earth Method of producing water-absorbing material
CN101484142A (en) * 2006-03-24 2009-07-15 奥克思利尤姆国际控股公司 Stabilized compositions containing alkaline labile drugs
CN201189241Y (en) * 2008-03-17 2009-02-04 陈潇 Sanitary towel with health-care function
CN104510573A (en) * 2013-10-08 2015-04-15 李建安 Sanitary pad for health observation

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