CN109846462B - Method and system for measuring blood sugar - Google Patents
Method and system for measuring blood sugar Download PDFInfo
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Abstract
The method for measuring the blood sugar comprises the steps of obtaining a fingertip measurement blood sugar value and a blood sugar change value by detecting a fingertip of a tester, then calculating a blood sugar correction value, and finally calculating an instant blood sugar concentration through the blood sugar correction value and an instant blood sugar parameter. The method provided by the invention can be used for measuring the fluctuation of the fingertip spectral transmittance of a tester to obtain the blood sugar change value of the tester, converting the spectral test on the body surface of a human body into the measurement of the fluctuation of the fingertip spectral transmittance, and measuring the glucose content in tissues such as muscles and skin of the human body without testing the glucose content, so that the interference of the tissues such as the muscles and the skin in the body of the tester on the glucose component is reduced. Compared with the prior art, the scheme disclosed by the invention can be used for comprehensively excluding glucose of tissues such as muscles, skins and the like in the body of the tester from the measurement parameters, so that the noise interference of the measurement is effectively reduced, and the measurement accuracy is improved.
Description
Technical Field
The present application relates to the field of blood glucose testing, and in particular, to a method and system for measuring blood glucose.
Background
The glucose in the blood is called blood glucose. Glucose is an important constituent of the human body and also an important source of energy. The normal human body needs a lot of sugar every day to provide energy, and provides power for the normal operation of various tissues and organs. Blood glucose must be maintained at a certain level to maintain the needs of the organs and tissues in the body. The fasting blood glucose concentration of normal people in the early morning is 3.9 mmol/L-6.0 mmol/L. Fasting plasma glucose concentrations exceed 6.0mmol/L, which is called hyperglycemia. Blood glucose concentrations below 3.9mmol/L are termed hypoglycemia. Since the blood glucose concentration changes with daily activities such as diet and exercise, it is necessary to monitor blood glucose in real time so as to effectively prevent hyperglycemia and to detect diseases such as diabetes in advance.
In order to avoid the damage to the human body caused by blood sampling detection, a noninvasive detection method which does not cause damage to the human body is mainly adopted to detect the blood glucose concentration at present. The currently used method for non-invasive measurement of blood glucose is a spectrum test, because the content of glucose in human blood is relatively low, and many glucose components exist in tissues such as muscle and skin of human body. Because the glucose content in human blood is tested and the glucose content in tissues such as human muscles and skin is also tested, the spectrum emitted by the spectrum test can be interfered by the glucose components in the tissues such as the human muscles and skin after passing through the human body, so that the glucose content in the blood is difficult to accurately calculate by the spectrum test method, the precision of the test result is reduced, and the expected effect cannot be achieved.
Therefore, how to reduce the interference of glucose components in tissues such as muscles and skin of a human body in the blood glucose measurement process and improve the blood glucose measurement accuracy becomes an urgent problem to be solved.
Disclosure of Invention
The invention provides a method and a system for measuring blood sugar, which solve the problem of blood sugar measurement result deviation caused by the interference of tissues such as muscle, skin and the like of a human body on glucose components in the blood sugar measurement process.
According to a first aspect, the present invention discloses a method of measuring blood glucose, comprising the steps of:
obtaining a fingertip test blood sugar value;
measuring the fluctuation of the fingertip spectrum light transmittance through a glucose light absorbance tester to obtain a blood glucose change value;
calculating to obtain a blood sugar correction value according to the fingertip test blood sugar value and the blood sugar change value;
and acquiring an instant blood sugar parameter, and calculating to obtain an instant blood sugar concentration according to the blood sugar correction value and the instant blood sugar parameter.
Optionally, the step of measuring the fluctuation of the fingertip spectral transmittance by a glucose absorbance tester to obtain the blood glucose variation value includes the following steps:
acquiring an average value of a fingertip glucose level value through a glucose absorbance tester;
and calculating to obtain a blood sugar change value according to the average value of the fingertip glucose level values.
Optionally, the obtaining the average value of the fingertip glucose level value by the glucose absorbance tester comprises the following steps:
obtaining the peak level value D of n fluctuation cycles of the fingertip glucose through a glucose absorbance testerf1、Df2……DfnSum valley level value Db1、Db2……Dbn；
According to the peak level value Df1、Df2……DfnAnd said valley level value Db1、Db2……DbnCalculating an average value of said peak level values
And average value of said valley level value
Alternatively, the blood glucose variation value is based on the average of the peak level values
Average of sum valley level values
Calculated according to the following formula:
wherein D is a blood glucose change value.
Optionally, the blood glucose correction value is calculated according to the blood glucose value and the blood glucose variation value measured by the fingertip according to the following formula:
A2＝A1-D,
in the formula, A2As a correction of blood glucose, A1Blood glucose values were tested for fingertips.
Optionally, obtaining an instant blood glucose parameter, and calculating an instant blood glucose concentration according to the blood glucose correction value and the instant blood glucose parameter according to the following formula:
A3＝A+A2，
in the formula, A3Is the instant blood glucose concentration, and A is the instant blood glucose parameter.
According to a second aspect, the invention discloses a system for measuring blood sugar, comprising a fingertip test blood sugar value obtaining unit, a blood sugar change value obtaining module, a blood sugar correction value calculating module and an instant blood sugar concentration calculating module, wherein:
the fingertip test blood sugar value acquisition unit and the blood sugar change value acquisition module are in signal connection with the blood sugar correction value calculation module, and the instant blood sugar concentration calculation module is in signal connection with the blood sugar correction value calculation module;
the fingertip test blood sugar value acquisition module is used for acquiring a fingertip test blood sugar value;
the blood glucose change value acquisition module is used for measuring the fluctuation of the fingertip spectrum light transmittance through a glucose light absorbance tester to obtain a blood glucose change value;
the blood sugar correction value calculation module is used for calculating a blood sugar correction value according to the fingertip test blood sugar value and the blood sugar change value;
and the instant blood sugar concentration calculation module is used for acquiring instant blood sugar parameters and calculating instant blood sugar concentration according to the blood sugar correction value and the instant blood sugar parameters.
Optionally, the blood glucose variation value obtaining module comprises a fingertip glucose level average value obtaining unit and a blood glucose variation value calculating unit, wherein:
the fingertip glucose level average value acquisition unit is in signal connection with the blood glucose change value calculation unit;
the fingertip glucose level average value acquisition unit is used for acquiring the level value of the fingertip glucose and calculating the average value of the fingertip glucose level value according to the level value of the fingertip glucose;
and the blood sugar change value calculating unit is used for calculating the blood sugar change value according to the average value of the fingertip glucose level values.
According to a third aspect, the invention discloses a computer apparatus comprising a processor for executing a computer program stored in a memory to implement the method of any of the first aspects above.
According to a fourth aspect, the invention discloses a computer-readable storage medium having a computer program stored thereon, characterized in that a processor is configured to execute the computer program stored in the storage medium to implement the method of any of the first aspects described above.
According to the technical scheme, the method and the system for measuring the blood sugar are provided, and the method for measuring the blood sugar comprises the steps of obtaining a fingertip test blood sugar value; measuring the fluctuation of the fingertip spectrum light transmittance through a glucose light absorbance tester to obtain a blood glucose change value; calculating to obtain a blood sugar correction value according to the fingertip test blood sugar value and the blood sugar change value; and acquiring an instant blood sugar parameter, and calculating to obtain an instant blood sugar concentration according to the blood sugar correction value and the instant blood sugar parameter. The method provided by the invention can be used for measuring the fluctuation of the fingertip spectral transmittance of a tester to obtain the blood sugar change value of the tester, converting the spectral test on the body surface of a human body into the measurement of the fluctuation of the fingertip spectral transmittance, and measuring the glucose content in tissues such as muscles and skin of the human body without testing the glucose content, so that the interference of the tissues such as the muscles and the skin in the body of the tester on the glucose component is reduced. Compared with the prior art, the scheme disclosed by the invention can be used for comprehensively excluding glucose of tissues such as muscles, skins and the like in the body of the tester from the measurement parameters, so that the noise interference of the measurement is effectively reduced, and the measurement accuracy is improved.
Drawings
In order to more clearly explain the technical solution of the present application, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious to those skilled in the art that other drawings can be obtained according to the drawings without any creative effort.
FIG. 1 is a flow chart of a method for measuring blood glucose according to an embodiment of the present application;
FIG. 2 is a flow chart of a method for measuring blood glucose according to an embodiment of the present application;
fig. 3 is a block diagram of a system for measuring blood glucose according to an embodiment of the present disclosure;
fig. 4 is a block diagram illustrating a structure of a blood glucose variation value obtaining module of a system for measuring blood glucose according to an embodiment of the present disclosure;
FIG. 5 is a block diagram of a glucose absorbance measuring instrument.
Illustration of the drawings:
wherein, the 11-fingertip test blood sugar value acquisition module; 12-a blood glucose change value acquisition module; 13-a blood glucose correction value calculation module; 14-an instant blood glucose concentration calculation module; 121-a fingertip glucose level average value acquisition unit; 122-blood glucose change value calculation unit.
Detailed Description
The technical solutions in the embodiments of the present application are clearly and completely described below with reference to the drawings in the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present application, but the present application may be practiced in other ways than those described again, and it will be apparent to those of ordinary skill in the art that the present application is not limited to the specific embodiments disclosed below.
Referring to fig. 1, fig. 1 is a flowchart of a method for measuring blood glucose according to an embodiment of the present disclosure. The method for measuring blood sugar comprises the following steps:
and S101, obtaining a fingertip blood sugar test value.
The testers performed blood glucose tests thirty minutes before and thirty minutes after a meal within one week. The tester punctures the fingertip through the glucometer, then takes out the test paper, inserts the test paper into the glucometer, takes out the machine after the glucometer makes a sound and the test paper is full of blood, then reads the data, and the obtained value is the fingertip blood sugar testing value.
And S102, measuring the fluctuation of the fingertip spectrum light transmittance through a glucose absorbance tester to obtain a blood glucose change value.
Referring to fig. 5, fig. 5 is a block diagram of a glucose absorbance measuring instrument. The tester puts fingers into a glucose light absorption rate tester, the glucose light absorption rate tester comprises a light emitter, a light receiver, a light amplifier, a digital-to-analog converter and a data processor, the light emitter emits a spectrum with the wavelength of 505nm, the spectrum passes through the fingertip of the tester, the light receiver receives the spectrum passing through the fingertip of the tester and then is amplified by the light amplifier, and then the digital-to-analog converter converts a digital signal into an analog signal to obtain a peak level value and a trough level value.
The blood glucose absorption rate is obtained by dividing the average value of the peak level value by the average value of the valley level value, namely the blood glucose change value.
And S103, calculating to obtain a blood sugar correction value according to the fingertip test blood sugar value and the blood sugar change value.
The blood sugar correction value reflects the relation between the fingertip test blood sugar value and the blood sugar change value measured by the tester at ordinary times.
Alternatively, after the blood sugar correction value is calculated, the blood sugar correction value is stored in the database, and the blood sugar correction value can be directly calculated when the instant blood sugar concentration is calculated.
And S104, acquiring an instant blood sugar parameter, and calculating to obtain an instant blood sugar concentration according to the blood sugar correction value and the instant blood sugar parameter.
Referring to fig. 2, fig. 2 is a flowchart of a method for measuring blood glucose according to an embodiment of the present invention, the method for measuring blood glucose includes the following steps:
s201, obtaining the blood sugar value of the fingertip test.
And S202, acquiring the average value of the fingertip glucose level value through a glucose absorbance tester.
The average value of the above-mentioned fingertip glucose level values is obtained by obtaining fingertip glucose n fluctuation cyclesPeak level value Df1、Df2……DfnSum valley level value Db1、Db2……Dbn；
According to the peak level value Df1、Df2……DfnAnd said valley level value Db1、Db2……DbnCalculating an average value of said peak level values
And average value of said valley level value
The n wave periods of the fingertip glucose are ten wave periods.
S203, calculating to obtain a blood glucose change value according to the average value of the fingertip glucose level values;
the blood glucose variation value is based on the average value of the peak level values
And average value of said valley level value
Calculated according to the following formula:
wherein D is a blood glucose change value.
And S204, calculating to obtain a blood sugar correction value according to the fingertip test blood sugar value and the blood sugar change value.
And calculating a blood sugar correction value according to the fingertip test blood sugar value and the blood sugar change value according to the following formula:
A2＝A1-D,
in the formula, A2As a correction of blood glucose, A1Blood glucose values were tested for fingertips.
And S205, acquiring an instant blood sugar parameter, and calculating to obtain an instant blood sugar concentration according to the blood sugar correction value and the instant blood sugar parameter.
And obtaining an instant blood glucose concentration by the obtaining of the instant blood glucose parameter and according to the blood glucose correction value and the instant blood glucose parameter and the following formula:
A3＝A+A2，
in the formula, A3Is the instant blood glucose concentration, and A is the instant blood glucose parameter.
According to the technical scheme, the method for measuring the blood sugar comprises the steps of obtaining a fingertip test blood sugar value; measuring the fluctuation of the fingertip spectrum light transmittance through a glucose light absorbance tester to obtain a blood glucose change value; calculating to obtain a blood sugar correction value according to the fingertip test blood sugar value and the blood sugar change value; and acquiring an instant blood sugar parameter, and calculating to obtain an instant blood sugar concentration according to the blood sugar correction value and the instant blood sugar parameter. The method provided by the invention can be used for measuring the fluctuation of the fingertip spectral transmittance of a tester to obtain the blood sugar change value of the tester, converting the spectral test on the body surface of a human body into the measurement of the fluctuation of the fingertip spectral transmittance, and measuring the glucose content in tissues such as muscles and skin of the human body without testing the glucose content, so that the interference of the tissues such as the muscles and the skin in the body of the tester on the glucose component is reduced. Compared with the prior art, the scheme disclosed by the invention can be used for comprehensively excluding glucose of tissues such as muscles, skins and the like in the body of the tester from the measurement parameters, so that the noise interference of the measurement is effectively reduced, and the measurement accuracy is improved.
Referring to fig. 3, fig. 3 is a block diagram of a system for measuring blood glucose according to an embodiment of the present invention, the system for measuring blood glucose includes a fingertip test blood glucose value obtaining module 11, a blood glucose variation value obtaining module 12, a blood glucose correction value calculating module 13, and an instant blood glucose concentration calculating module 14, wherein:
the fingertip test blood sugar value acquisition module 11 and the blood sugar change value acquisition module 12 are in signal connection with the blood sugar correction value calculation module 13, and the instant blood sugar concentration calculation module is in signal connection with the blood sugar correction value calculation module 13;
the fingertip test blood sugar value acquisition module 11 is used for acquiring a fingertip test blood sugar value;
the blood glucose change value acquisition module 12 is configured to measure fluctuations in the fingertip spectral transmittance through a glucose absorbance tester to obtain a blood glucose change value;
the blood sugar correction value calculation module 13 is configured to calculate a blood sugar correction value according to the fingertip test blood sugar value and the blood sugar change value;
and the instant blood sugar concentration calculating module 14 is configured to obtain an instant blood sugar parameter, and calculate an instant blood sugar concentration according to the blood sugar correction value and the instant blood sugar parameter.
Referring to fig. 4, a block diagram of a blood glucose variation value obtaining module of a system for measuring blood glucose according to an embodiment of the present invention is shown. The blood glucose variation value acquisition module 12 includes a fingertip glucose level average value acquisition unit 121 and a blood glucose variation value calculation unit 122, wherein:
the fingertip glucose level average value acquisition unit 121 is in signal connection with the blood glucose change value calculation unit 122;
the fingertip glucose level average value acquiring unit 121 is configured to acquire a level value of a fingertip glucose, and calculate an average value of the fingertip glucose level values according to the level value of the fingertip glucose;
the blood glucose variation value calculating unit 122 is configured to calculate a blood glucose variation value according to the average value of the fingertip glucose level values.
In addition, an embodiment of the present invention further provides a computer apparatus, where a processor executes the computer instructions, so as to implement the following method:
obtaining a fingertip test blood sugar value; measuring the fluctuation of the fingertip spectrum light transmittance through a glucose light absorbance tester to obtain a blood glucose change value; calculating to obtain a blood sugar correction value according to the fingertip test blood sugar value and the blood sugar change value; and acquiring an instant blood sugar parameter, and calculating to obtain an instant blood sugar concentration according to the blood sugar correction value and the instant blood sugar parameter. The method provided by the invention can be used for measuring the fluctuation of the fingertip spectral transmittance of a tester to obtain the blood sugar change value of the tester, converting the spectral test on the body surface of a human body into the measurement of the fluctuation of the fingertip spectral transmittance, and measuring the glucose content in tissues such as muscles and skin of the human body without testing the glucose content, so that the interference of the tissues such as the muscles and the skin in the body of the tester on the glucose component is reduced. Compared with the prior art, the scheme disclosed by the invention can be used for comprehensively excluding glucose of tissues such as muscles, skins and the like in the body of the tester from the measurement parameters, so that the noise interference of the measurement is effectively reduced, and the measurement accuracy is improved.
It will be understood by those skilled in the art that all or part of the processes of the methods of the embodiments described above can be implemented by a computer program, which can be stored in a computer-readable storage medium, and when executed, can include the processes of the embodiments of the methods described above. The storage medium may be a magnetic disk, an optical disk, a read-only memory (ROM), a Random Access Memory (RAM), or the like. The computer processor is used to execute a computer program stored in a storage medium to implement the following method:
obtaining a fingertip test blood sugar value; measuring the fluctuation of the fingertip spectrum light transmittance through a glucose light absorbance tester to obtain a blood glucose change value; calculating to obtain a blood sugar correction value according to the fingertip test blood sugar value and the blood sugar change value; and acquiring an instant blood sugar parameter, and calculating to obtain an instant blood sugar concentration according to the blood sugar correction value and the instant blood sugar parameter. The method provided by the invention can be used for measuring the fluctuation of the fingertip spectral transmittance of a tester to obtain the blood sugar change value of the tester, converting the spectral test on the body surface of a human body into the measurement of the fluctuation of the fingertip spectral transmittance, and measuring the glucose content in tissues such as muscles and skin of the human body without testing the glucose content, so that the interference of the tissues such as the muscles and the skin in the body of the tester on the glucose component is reduced. Compared with the prior art, the scheme disclosed by the invention can be used for comprehensively excluding glucose of tissues such as muscles, skins and the like in the body of the tester from the measurement parameters, so that the noise interference of the measurement is effectively reduced, and the measurement accuracy is improved.
The foregoing is merely an example of the present invention and common general knowledge of known specific structures and features of the embodiments is not described herein in any greater detail. It should be noted that variations and modifications can be made by those skilled in the art without departing from the structure of the present invention. These should also be construed as the scope of the present invention, and they should not be construed as affecting the effectiveness of the practice of the present invention or the applicability of the patent. The scope of the claims of the present application shall be determined by the contents of the claims, and the description of the embodiments and the like in the specification shall be used to explain the contents of the claims.
Claims (6)
1. A method of measuring blood glucose, the method comprising the steps of:
obtaining a fingertip test blood sugar value;
measuring the fluctuation of the fingertip spectrum light transmittance through a glucose light absorbance tester to obtain a blood glucose change value;
calculating to obtain a blood sugar correction value according to the fingertip test blood sugar value and the blood sugar change value;
obtaining an instant blood glucose parameter, and calculating to obtain an instant blood glucose concentration according to the blood glucose correction value and the instant blood glucose parameter;
the measuring of the fluctuation of the fingertip spectrum light transmittance through the glucose absorbance tester to obtain the blood glucose change value comprises the following steps:
acquiring an average value of a fingertip glucose level value through a glucose absorbance tester;
calculating to obtain a blood glucose change value according to the average value of the fingertip glucose level values; the step of obtaining the average value of the fingertip glucose level value through the glucose absorbance tester comprises the following steps:
obtaining the peak level value D of n fluctuation cycles of the fingertip glucose through a glucose absorbance testerf1、Df2……DfnSum valley level value Db1、Db2……Dbn；
According to the peak level value Df1、Df2……DfnAnd said valley level value Db1、Db2……DbnCalculating an average value of said peak level values
And average value of said valley level value
The blood glucose variation value is based on the average value of the peak level values
And average value of said valley level value
Calculated according to the following formula:
wherein D is a blood glucose change value.
2. The method for measuring blood glucose according to claim 1, wherein said blood glucose correction value is calculated from said fingertip test blood glucose value and said blood glucose variation value according to the following formula:
A2＝A1-D, in which A2As a correction of blood glucose, A1Blood glucose values were tested for fingertips.
3. The method of measuring blood glucose of claim 2, wherein said obtaining an instantaneous blood glucose parameter, and calculating an instantaneous blood glucose concentration based on said blood glucose correction value and said instantaneous blood glucose parameter according to the following formula:
A3＝A+A2in the formula, A3Is the instant blood glucose concentration, and A is the instant blood glucose parameter.
4. A system for measuring blood sugar is characterized by comprising a fingertip test blood sugar value acquisition unit, a blood sugar change value acquisition module, a blood sugar correction value calculation module and an instant blood sugar concentration calculation module, wherein:
the fingertip test blood sugar value acquisition unit and the blood sugar change value acquisition module are in signal connection with the blood sugar correction value calculation module, and the instant blood sugar concentration calculation module is in signal connection with the blood sugar correction value calculation module;
the fingertip test blood sugar value acquisition module is used for acquiring a fingertip test blood sugar value;
the blood glucose change value acquisition module is used for measuring the fluctuation of the fingertip spectrum light transmittance through a glucose light absorbance tester to obtain a blood glucose change value;
the blood sugar correction value calculation module is used for calculating a blood sugar correction value according to the fingertip test blood sugar value and the blood sugar change value;
the instant blood sugar concentration calculation module is used for obtaining instant blood sugar parameters and calculating instant blood sugar concentration according to the blood sugar correction value and the instant blood sugar parameters;
the blood sugar variation value acquisition module comprises a fingertip glucose level average value acquisition unit and a blood sugar variation value calculation unit, wherein:
the fingertip glucose level average value acquisition unit is in signal connection with the blood glucose change value calculation unit;
the fingertip glucose level average value acquisition unit is used for acquiring a level value of fingertip glucose and calculating an average value of the fingertip glucose level values according to the level value of the fingertip glucose;
the blood sugar variation value calculating unit is used for calculating a blood sugar variation value according to the average value of the fingertip glucose level values;
the step of obtaining the average value of the fingertip glucose level value through the glucose absorbance tester comprises the following steps:
obtaining the peak level value D of n fluctuation cycles of the fingertip glucose through a glucose absorbance testerf1、Df2……DfnSum valley level value Db1、Db2……Dbn；
According to the peak level value Df1、Df2……DfnAnd said valley level value Db1、Db2……DbnCalculating an average value of said peak level values
And average value of said valley level value
The blood glucose variation value is based on the average value of the peak level values
And average value of said valley level value
Calculated according to the following formula:
wherein D is a blood glucose change value.
5. A computer arrangement comprising a processor for executing a computer program stored in a memory to implement the method of any one of claims 1-3.
6. A computer-readable storage medium, on which a computer program is stored, characterized in that a processor is adapted to execute the computer program stored in the storage medium to implement the method according to any of claims 1-3.
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| CN101305915A (en) * | 2008-07-16 | 2008-11-19 | 深圳华为通信技术有限公司 | Mobile terminal for measuring blood sugar and method |
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