CN109781858A - Central venous catheter measuring device and method - Google Patents

Central venous catheter measuring device and method Download PDF

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Publication number
CN109781858A
CN109781858A CN201811638049.4A CN201811638049A CN109781858A CN 109781858 A CN109781858 A CN 109781858A CN 201811638049 A CN201811638049 A CN 201811638049A CN 109781858 A CN109781858 A CN 109781858A
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China
Prior art keywords
fluid
circuit
central venous
venous catheter
vascular
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CN201811638049.4A
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Chinese (zh)
Inventor
鄢建军
宁勇
徐钢
张仲华
杨建国
朱波
叶琴
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Tongji Hospital Affiliated To Tongji Medical College Of Huazhong University Of Science & Technology
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Tongji Hospital Affiliated To Tongji Medical College Of Huazhong University Of Science & Technology
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Priority to CN201811638049.4A priority Critical patent/CN109781858A/en
Publication of CN109781858A publication Critical patent/CN109781858A/en
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Abstract

The present invention discloses a kind of central venous catheter measuring device and method.Described device includes: lumen model, is configured to the vein of simulation human body, and is placed into and is removed the tube body of central venous catheter;Vascular circuit component is configured to form the fluid state of fluid in the vascular circuit and vascular circuit component vascular circuit according to preset state modulator of simulation human body with the lumen model;Dialysis circuit component, the composition dialysis circuit and the dialysis circuit component for being configured to dismantle with the input interface of the central venous catheter and output interface are configured as the fluid that purification passes through the dialysis circuit;Detection components are configured as the probability that the fluid after detection is cleaned under presently described fluid state again returns to the dialysis circuit from the vascular circuit.

Description

Central venous catheter measuring device and method
Technical field
The present invention relates to medical instruments fields more particularly to a kind of for calm in central venous catheter for hemodialysis Arteries and veins conduit measuring device and method.
Background technique
Central venous catheter belongs to one kind of blood vessel inner tube, is typically interposed in the jugular vein or femoral vein of sufferer. Central venous catheter includes an input terminal and an output end, is at least formed for the dialysis machine with outside saturating for blood The dialysis circuit of analysis.
During cardiac vein conduit in use carries out haemodialysis, purifies and be transported in vein through dialysis circuit Blood can part slave drain pipe it is reverse flow to input terminal, and again enter dialysis circuit;Blood after purification Being re-introduced into dialysis circuit will affect the therapeutic effect of haemodialysis, and interference medical staff to the abundant degree of sufferer dialysis Assessment.
Some researches show that the central venous catheter of different structure and/or unlike material to be again introduced into purified blood There is apparent influence in analysis circuit.The influence that so inspection center's ductus venosus is again introduced into dialysis circuit to blood after purification is weight It wants.
Summary of the invention
The embodiment of the present invention at least discloses a kind of central venous catheter measuring device, can be returned by simulating the blood vessel of human body The dialysis circuit inspection center ductus venosus of road and standard returns the blood purified in dialysis circuit from blood in haemodialysis Road returns to the probability of dialysis circuit.
Described device includes:
Lumen model, is configured to the vein of simulation human body, and is placed into and is removed the tube body of central venous catheter;
Vascular circuit component is configured to form the vascular circuit and the blood of simulation human body with the lumen model The fluid state of tube loop component fluid in the vascular circuit according to preset state modulator;
Dialysis circuit component is configured to the composition dismantled with the input interface of the central venous catheter and output interface Dialysis circuit and the dialysis circuit component are configured as the fluid that purification passes through the dialysis circuit;
Detection components are configured as the fluid after detection is cleaned under presently described fluid state from the vascular circuit Again return to the probability of the dialysis circuit.
In some embodiments disclosed by the invention, the vascular circuit component include with the lumen model composition described in The circulation pipe of vascular circuit and set pipe three-way device;
The first port for setting pipe three-way device is connect with the first port of the lumen model, and second port passes through described Circulation pipe is connect with the second port of the lumen model, and the third port being placed into and being removed in described for sealing The tube body of cardiac vein conduit;
The vascular circuit component includes the first transfer tube, and first transfer tube is configured in the circulation pipe, and First transfer tube is configured as driving the fluid in the circulation pipe to flow, and according to the control of the first external signal The flow rate of fluid.
In some embodiments disclosed by the invention, the vascular circuit component includes temperature controller;
The temperature controller is configured in the circulation pipe, and controls the fluid temperature (F.T.) of fluid in the circulation pipe.
In some embodiments disclosed by the invention, the vascular circuit component include fluid infusion three-way device, fluid infusion container and Liquid supplementation pipe;
The first end and the second end pipe of the fluid infusion three-way device connect in the circulation pipe, and third end connects institute by liquid supplementation pipe State fluid infusion container.
In some embodiments disclosed by the invention, the dialysis circuit component include inlet tube, drain pipe, dialyzer and Second transfer tube;
The input interface of the connection central venous catheter of one end disassembly of the inlet tube, the other end pass through artery pot It is connect with the entrance of the dialyzer;
The output interface of the connection central venous catheter of one end disassembly of the drain pipe, the other end pass through venous chambers It is connect with the outlet of the dialyzer;
Second transfer tube is configured in the inlet tube and second transfer tube be configured as driving it is described into Fluid in liquid pipe flows, and the flow rate of the fluid is controlled according to the second external signal.
In some embodiments disclosed by the invention, the detection components include dilution tube, ultrasonic transmitter-receiver and ultrasound Wave processor;
One end of the dilution tube is connect with the venous chambers or the drain pipe, other end connection measurement container;
The ultrasonic transmitter-receiver includes energy converter and probe;
The energy converter and it is described probe respectively be configured in the inlet tube and the drain pipe;
The energy converter be configured to respond to the processor for ultrasonic wave the dialysis circuit send ultrasonic wave;
The probe is configured as receiving the ultrasonic wave along dialysis circuit transmitting;
It is described after the measurement container injects dilution to the venous chambers or the drain pipe by the dilution tube Processor for ultrasonic wave sends ultrasound according to the energy converter under presently described fluid state and involves the probe reception ultrasonic wave Time difference detection dilution the probability of the drain pipe is entered from the vascular circuit.
In some embodiments disclosed by the invention, the ultrasonic transmitter-receiver includes the energy converter of two transmitting ultrasonic waves And the probe of two reception ultrasonic waves;
The inlet tube and the drain pipe respectively be configured with the energy converter and a probe;
Two energy converters are configured to respond to the relatively reversed in the dialysis circuit of the processor for ultrasonic wave Send ultrasonic wave, the ultrasonic wave that the reception of two probe difference is transmitted along the dialysis circuit;
It is described after the measurement container injects dilution to the venous chambers or the drain pipe by the dilution tube Processor for ultrasonic wave involves two probes according to two energy converters transmission ultrasounds under presently described fluid state and connects The time difference detection dilution for receiving ultrasonic wave enters the probability of the drain pipe from the vascular circuit.
In some embodiments disclosed by the invention, the detection components include temperature controller, temperature sensor and temperature Spend processor;
The temperature controller is configured in the outlet tube or the venous chambers and temperature controller response institute State Temperature processor control entered from the dialysis circuit vascular circuit fluid output fluid temperature;
The temperature sensor be configured in the inlet tube or the artery pot and the temperature sensor detection from The vascular circuit enters the input fluid temperature (F.T.) of the fluid of the dialysis circuit;
The Temperature processor detects fluid and returns from the blood vessel according to the input fluid temperature (F.T.) and output fluid temperature Road enters the probability of the drain pipe.
The embodiment of the present invention at least discloses a kind of central venous catheter measurement method;
The described method includes:
Establish the vascular circuit of simulation human body;
Establish the dialysis circuit for being used for haemodialysis;
Central venous catheter to be measured is chosen, and the tube body of the central venous catheter is placed in the blood vessel and is returned Road, input interface and output interface are reversely connected respectively at the both ends of the dialysis circuit;
It is detected in the dialysis circuit through the purified fluid of the dialysis circuit, is again returned to described by detection components The probability of dialysis circuit.
In some embodiments disclosed by the invention, after detecting the probability;
It is described general under reversal connection state that the detection components by ultrasonic wave dilution method measure the central venous catheter Rate.
For above scheme, the present invention is by being referring to the drawings described in detail disclosed exemplary embodiment, also The other feature and its advantage for making the embodiment of the present invention understand.
Detailed description of the invention
In order to illustrate the technical solution of the embodiments of the present invention more clearly, below will be to needed in the embodiment attached Figure is briefly described, it should be understood that the following drawings illustrates only certain embodiments of the present invention, therefore is not construed as pair The restriction of range for those of ordinary skill in the art without creative efforts, can also be according to this A little attached drawings obtain other relevant attached drawings.
Fig. 1 is the schematic diagram of center ductus venosus measuring device.
Specific embodiment
In order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below in conjunction with the embodiment of the present invention In attached drawing, technical scheme in the embodiment of the invention is clearly and completely described, it is clear that described embodiment is A part of the embodiment of the present invention, instead of all the embodiments.The present invention being usually described and illustrated herein in the accompanying drawings is implemented The component of example can be arranged and be designed with a variety of different configurations.
The present embodiment discloses a kind of central venous catheter measuring device;It is mainly used for measuring different central venous catheter in blood In the therapeutic process of liquid dialysis, it is dialyzed the probability that the purified blood in circuit is re-introduced into central venous catheter.
Referring to FIG. 1, device includes lumen model 6, vascular circuit component, dialysis circuit component and detection components.Lumen Model 6 is used to simulate the jugular vein or femoral vein of human body, simulates venous anatomy to greatest extent.Vascular circuit assembly body is used for The vascular circuit for forming simulation human body with lumen model 6 enables blood in lumen model for simulating the venous return line of human body The flowing recycled in 6.The group that the input terminal 1 and output interface 2 of dialysis circuit component and central venous catheter to be measured are dismantled At dialysis circuit, for being purified to the blood for entering dialysis circuit from lumen model 6.Detection components are in current blood Detection is dialyzed the probability that the purified blood in circuit is re-introduced into central venous catheter from vascular circuit under flow regime.
The vascular circuit component of the present embodiment includes merging three-way device 19, circulation pipe 21, extracorporal circulatory system peristaltic pump 20, fluid infusion Triple valve 25, liquid supplementation pipe 24, titration pot 23, fluid infusion container 22 and constant temperature water tank 26.
The lower end that three-way device 19 is placed in Fig. 1 is connect with the upper end of lumen model 6, what left upper end was detoured by circulation pipe 21 It is connect with the lower end of lumen model 6, upper right side is used to be placed in or take out the tube body 3 of central venous catheter.Circulation pipe 21 passes through body Outer circulation peristaltic pump 20 drives its internal blood filled.The vascular circuit of so the present embodiment simulation passes through above-mentioned vascular circuit Component and lumen model 6 form, and make the blood in lumen model 6 according to the given blood rate of extracorporal circulatory system peristaltic pump 20 and side To flowing.
Meanwhile first end and the second end access of fluid infusion triple valve 25 is in circulation pipe 21, third end by liquid supplementation pipe 24 and Titration pot 23 is connect with fluid infusion container 22;So fluid infusion container 22 can the supplemental blood in vascular circuit at any time, for disappearing The loss generated after dialysis circuit and central venous catheter except blood.
Preferably, circulation pipe 21 passes through constant temperature water tank 26, being capable of blood temperature in control loop pipe 21.
Preferably, the present embodiment is mounted with several shut-off valves (2,4,12,13) and cut-offs relevant pipe for interim Road.
The dialysis circuit component of the present embodiment includes inlet tube 11, drain pipe 12, dialyzer 16 and dialysis machine peristaltic pump 14. One end pipe of inlet tube 11 connects the input terminal 1 of central venous catheter, and the other end is connected by the entrance of artery pot 15 and dialyzer 16 It connects;One end pipe of drain pipe 12 connects the output interface 2 of central venous catheter, and the other end is gone out by venous chambers 17 and dialyzer 16 Mouthful connection, dialysis machine peristaltic pump 14 is installed in inlet tube 11 and dialysis machine peristaltic pump 14 drives the blood in inlet tube 11 Flowing.So the dialysis circuit component of the present embodiment can be taken out through inlet tube 11 by dialysis machine peristaltic pump 14 from lumen model 6 Suction blood recycles dialyzer 16 to purify blood, and purified blood is returned to pipe finally by drain pipe 12 Cavity mold type 6.
The detection components of the present embodiment include dilution tube 18, measurement container, ultrasonic transmitter-receiver and processor for ultrasonic wave.It is dilute The one end for releasing pipe 18 is connect with venous chambers 17, other end connection measurement container.
Ultrasonic transmitter-receiver includes two test sides 7, and test side 7 includes the energy converter and reception ultrasonic wave for sending ultrasonic wave Probe.Two test sides 7 respectively be installed in inlet tube 11 and drain pipe 12, energy converter and probe are and ultrasonication Device coupling.Two energy converters are able to respond processor for ultrasonic wave, and the transmission ultrasonic wave relatively reversed in dialysis circuit, and two The ultrasonic wave that the reception of probe difference is transmitted along dialysis circuit.
So, the detection components of the present embodiment utilize ultrasonic Method for Measuring, pass through the injection of dilution tube 18 one in measurement container After the physiological saline for determining concentration, since spread speed of the ultrasonic wave in blood and physiological saline is different.So through drain pipe 12 discharge physiological saline, or perhaps the blood of normal saline dilution be sucked again enter inlet tube 11 after, meeting Cause the variation of ultrasonic propagation time in dialysis circuit;
Processor for ultrasonic wave according to two ultrasonic propagation times for being detected after saline injection of popping one's head in detect into Enter the volume to inlet tube 11, and then realize the Probability Detection for entering back into central venous catheter to physiological saline, is i.e. blood is saturating The blood being cleaned in analysis enters back into the probability of central venous catheter.
Preferably, the ultrasonic transmitter-receiver of the present embodiment and processor for ultrasonic wave are supervised by TransonicHD02 haemodialysis It protects instrument and flow/dilution inductor equipped with ultrasonic probe replaces.Two flows/dilution inductor passes through Flow-QC points The rate energy of the control blood of other connection inlet tube 11 and drain pipe 12, extracorporal circulatory system peristaltic pump 20 and dialysis machine peristaltic pump 14 It is enough to be measured and controlled by HD02 haemodialysis patient monitor.The flow of inlet tube 11/dilution inductor detects the adverse current propagation time; The flow of drain pipe 12/dilution inductor detects downstream propagation times.When TransonicHD02 patient monitor is propagated by adverse current Between accumulation difference Accurate Determining blood flow flow between downstream propagation times.
Specifically, the spread speed of ultrasonic wave is 1533m/sec in isotonic physiological saline;Blood is according to plasma protein concentration It is 1560-1590m/sec in the spread speed of ultrasonic wave.
TransonicHD02 haemodialysis patient monitor and flow/dilution inductor equipped with ultrasonic probe can continue Detection dialysis circuit in ultrasonic wave spread speed.When venous chambers 17 by saline injection by hemodilution after, be diluted Blood enter back into inlet tube 11 and will cause the variation of ultrasonic propagation velocity in dialysis circuit.Passing through flow/dilution After inductor receives ultrasonic wave, TransonicHD02 haemodialysis patient monitor is with ultrasonic wave in dilution curve record dialysis circuit The variation of spread speed.
Dilution curve can be used to calculate hemodynamic parameter, and flow dilutes equation are as follows: Q=V/S, wherein V is physiology The amount of salt water, S are the area under dilution curve.
So the device of the present embodiment is corresponding dilute in the acquisition corresponding dilution curve of above-mentioned inlet tube 11 and drain pipe 12 After releasing curve, it is saturating in blood the central venous catheter with measurement can be obtained by TransonicHD02 haemodialysis patient monitor The probability for being cleaned blood is again aspirated in analysis;Specific calculating is as follows.
The area Sven of the corresponding dilution curve of drain pipe 12 is proportional to the amount Vinj of the physiological saline of injection, is equal to Sven Multiplied by pump flow control amount Qb, Vinj=Sven*Qb;
The area Sart of the corresponding dilution curve of inlet tube 11 is proportional to the amount Vrec of the physiological saline of recycling, is equal to Sart is multiplied by pump flow control amount QbX, Vrec=Sart*QbX;
So there is R%=Vrec/Vinj=Sart*QbX/Sven*Qb;
R% is the amount Vrec of physiological saline and the ratio of the amount Vinj of the physiological saline of injection, i.e. central venous catheter exist The probability for being cleaned blood is again aspirated in haemodialysis.
The present embodiment provides test and data to the implementation of above-mentioned central venous catheter measuring device.
Subjects are that the central vein of six different models measures conduit, specification be respectively 11.5F*13.5CM, 11.5F*16CM, 11.5F*20CM, 12F*/16CM and 12F*20CM.
Content of the test be in the case where 5 different velocity of blood flow, respectively measuring center vein measurement conduit just connecing and When reversal connection, make purified blood back to the probability of central vein measurement conduit;
Velocity of blood flow is 150ml/min to 200ml/min to 250ml/min to 300ml/min to 350ml/min respectively.
Test process is as follows.
Measure the central venous catheter that specification is 11.5F*13.5CM;
Selection Center ductus venosus is just connecing with inlet tube 11 and drain pipe 12, and dialysis machine peristaltic pump 14 is controlled in 150ml/ min;
The haemodialysis patient monitor selection path TransonicHD02 recycles option, passes through as required after signal stabilization Dilution tube 18 is in 17 saline injection 10ml of venous chambers;TransonicHD02 haemodialysis patient monitor is public by the calculating of R% Formula, acquisition are just connecing value of the blood flow velocity in 150ml/min under state;
It is measured at least three times under state and blood flow velocity in above-mentioned just connecing, and records numerical value respectively.Every completion is primary to survey After amount, by the liquid discharge of 16 ultrafiltration 10ml of dialyzer come to guarantee the stabilization of hemoglobin concentration in vascular circuit;
In the case where just connecing state with above-mentioned steps by dialysis machine peristaltic pump 14 adjust blood flow velocity be respectively 150ml/min, 200ml/min, 250ml/min, 300ml/min and 350ml/min;Measure the value of R% under each velocity of blood flow respectively again.
Selection Center ductus venosus and inlet tube 11 and drain pipe 12 are reversely connected;Above-mentioned steps are repeated, 5 Hemodynamic environments are measured Spend the value of lower R%.
The specification of central venous catheter is successively replaced again;It repeats the above steps, obtains the central venous catheter of six specifications The value of R% is just connect and is reversely connected under 5 different blood rates.
By above-mentioned test process, central venous catheter is found in blood dialysis, keeps purification blood reentrant Probability, it is only related with the outer diameter of conduit, it is unrelated with the length of conduit;The central venous catheter of different model under state is just being connect not It is 0 with the recirculation rate under flow status;The central venous catheter of different model is under different flow state under reversal connection state Recirculation rate it is as shown in the table.
By above-mentioned test, the device of the present embodiment can be led the central vein of different size under different blood flow rates R% of the pipe in reversal connection is measured.
The present embodiment is directed to above-mentioned apparatus, provides a kind of central venous catheter measurement method, specific step is as follows.
S100, the vascular circuit for establishing simulation human body;
S200, the dialysis circuit for being used for haemodialysis is established;
S300, central venous catheter to be measured is chosen, and the tube body of central venous catheter 3 is placed in vascular circuit, Input terminal 1 and output interface 2 are reversely connected respectively at the both ends of dialysis circuit;
S400, detection components are measured under reversal connection state by ultrasonic wave dilution method, through the purified fluid of dialysis circuit, Again return to the probability of dialysis circuit.
Embodiment three
The present embodiment separately discloses a kind of central venous catheter measuring device.The device of the present embodiment measures fluid by temperature Enter the probability of drain pipe 12 from vascular circuit
Device includes temperature controller, temperature sensor and Temperature processor.Temperature controller be configured in outlet tube or Venous chambers 17 and temperature controller response Temperature processor control from dialysis circuit enter vascular circuit fluid it is defeated Fluid temperature (F.T.) out.
Temperature sensor is configured in inlet tube 11 or artery pot 15 and temperature sensor detection enters from vascular circuit To the input fluid temperature (F.T.) of the fluid of dialysis circuit;
Temperature processor detects fluid from vascular circuit and enters drain pipe according to input fluid temperature (F.T.) and output fluid temperature 12 probability.
The foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention, for the skill of this field For art personnel, the invention may be variously modified and varied.All within the spirits and principles of the present invention, made any to repair Change, equivalent replacement, improvement etc., should all be included in the protection scope of the present invention.

Claims (10)

1. a kind of central venous catheter measuring device, which is characterized in that
Described device includes:
Lumen model, is configured to the vein of simulation human body, and is placed into and is removed the tube body of central venous catheter;
Vascular circuit component is configured to form the vascular circuit of simulation human body with the lumen model and the blood vessel returns The fluid state of road component fluid in the vascular circuit according to preset state modulator;
Dialysis circuit component is configured to dialyse with the composition that the input interface of the central venous catheter and output interface are dismantled Circuit and the dialysis circuit component are configured as the fluid that purification passes through the dialysis circuit;
Detection components are configured as detecting the fluid after being cleaned under presently described fluid state from the vascular circuit again Return to the probability of the dialysis circuit.
2. central venous catheter measuring device as described in claim 1, which is characterized in that
The vascular circuit component includes forming the circulation pipe of the vascular circuit with the lumen model and setting pipe three-way device;
The first port for setting pipe three-way device is connect with the first port of the lumen model, and second port passes through the circulation Pipe is connect with the second port of the lumen model, and the third port is calm in described for being placed into and being removed for sealing The tube body of arteries and veins conduit;
The vascular circuit component includes the first transfer tube, and first transfer tube is configured in the circulation pipe and described First transfer tube is configured as driving the fluid in the circulation pipe to flow, and controls the fluid according to the first external signal Flow rate.
3. central venous catheter measuring device as claimed in claim 2, which is characterized in that
The vascular circuit component includes temperature controller;
The temperature controller is configured in the circulation pipe, and controls the fluid temperature (F.T.) of fluid in the circulation pipe.
4. central venous catheter measuring device as claimed in claim 2, which is characterized in that
The vascular circuit component includes fluid infusion three-way device, fluid infusion container and liquid supplementation pipe;
The first end and the second end pipe of the fluid infusion three-way device connect in the circulation pipe, and third end connects the benefit by liquid supplementation pipe Liquid container.
5. central venous catheter measuring device as described in claim 1, which is characterized in that
The dialysis circuit component includes inlet tube, drain pipe, dialyzer and the second transfer tube;
The input interface of the connection central venous catheter of one end disassembly of the inlet tube, the other end pass through artery pot and institute State the entrance connection of dialyzer;
The output interface of the connection central venous catheter of one end disassembly of the drain pipe, the other end pass through venous chambers and institute State the outlet connection of dialyzer;
Second transfer tube is configured in the inlet tube and second transfer tube is configured as driving the inlet tube In fluid flowing, and control according to the second external signal the flow rate of the fluid.
6. central venous catheter measuring device as claimed in claim 5, which is characterized in that
The detection components include dilution tube, ultrasonic transmitter-receiver and processor for ultrasonic wave;
One end of the dilution tube is connect with the venous chambers or the drain pipe, other end connection measurement container;
The ultrasonic transmitter-receiver includes energy converter and probe;
The energy converter and it is described probe respectively be configured in the inlet tube and the drain pipe;
The energy converter be configured to respond to the processor for ultrasonic wave the dialysis circuit send ultrasonic wave;
The probe is configured as receiving the ultrasonic wave along dialysis circuit transmitting;
After the measurement container injects dilution to the venous chambers or the drain pipe by the dilution tube, the ultrasound Wave processor under presently described fluid state according to the energy converter send ultrasound involve it is described probe receive ultrasonic wave when Between difference detection dilution the probability of the drain pipe is entered from the vascular circuit.
7. central venous catheter measuring device as claimed in claim 6, which is characterized in that
The ultrasonic transmitter-receiver includes the energy converter of two transmitting ultrasonic waves and the probe of two reception ultrasonic waves;
The inlet tube and the drain pipe respectively be configured with the energy converter and a probe;
Two energy converters are configured to respond to the transmission relatively reversed in the dialysis circuit of the processor for ultrasonic wave Ultrasonic wave, the ultrasonic wave that the reception of two probe difference is transmitted along the dialysis circuit;
After the measurement container injects dilution to the venous chambers or the drain pipe by the dilution tube, the ultrasound It is super that wave processor involves two probes receptions according to two energy converters transmission ultrasounds under presently described fluid state The time difference detection dilution of sound wave enters the probability of the drain pipe from the vascular circuit.
8. central venous catheter measuring device as claimed in claim 5, which is characterized in that
The detection components include temperature controller, temperature sensor and Temperature processor;
The temperature controller is configured in the outlet tube or the venous chambers and the temperature controller responds the temperature The control of degree processor enters the output fluid temperature of the fluid of the vascular circuit from the dialysis circuit;
The temperature sensor is configured in the inlet tube or the artery pot and the temperature sensor is detected from described Vascular circuit enters the input fluid temperature (F.T.) of the fluid of the dialysis circuit;
The Temperature processor according to the input fluid temperature (F.T.) and output fluid temperature, detect fluid from the vascular circuit into Enter the probability of the drain pipe.
9. a kind of central venous catheter measurement method, which is characterized in that
The described method includes:
Establish the vascular circuit of simulation human body;
Establish the dialysis circuit for being used for haemodialysis;
Central venous catheter to be measured is chosen, and the tube body of the central venous catheter is placed in the vascular circuit, it is defeated Incoming interface and output interface are reversely connected respectively at the both ends of the dialysis circuit;
It is detected in the dialysis circuit through the purified fluid of the dialysis circuit by detection components, again returns to the dialysis The probability in circuit.
10. central venous catheter measurement method as claimed in claim 9, which is characterized in that
The detection components measure the probability of the central venous catheter under reversal connection state by ultrasonic wave dilution method.
CN201811638049.4A 2018-12-29 2018-12-29 Central venous catheter measuring device and method Pending CN109781858A (en)

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Application Number Priority Date Filing Date Title
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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010050256A1 (en) * 1994-09-16 2001-12-13 Krivitski Nikolai M. Method and apparatus to measure blood flow and recirculation in hemodialysis shunts
CN1436087A (en) * 2000-06-15 2003-08-13 株式会社Jms Automatic blood dialyzer and dialyzing method
JP2008132256A (en) * 2006-11-29 2008-06-12 Unitika Ltd Vascular access catheter
EP2565904A1 (en) * 2011-09-05 2013-03-06 Commissariat à l'Énergie Atomique et aux Énergies Alternatives Method and apparatus for estimating a molecular mass parameter in a sample
CN104069557A (en) * 2013-03-28 2014-10-01 B·布莱恩·阿维图姆股份公司 Method of detecting recirculation in an arteriovenous shunt during ongoing hemodialysis and dialysis system
CN105096717A (en) * 2015-09-06 2015-11-25 杨荣利 Blood purification simulation and demonstration system
JP2017198938A (en) * 2016-04-28 2017-11-02 ニプロ株式会社 Puncture simulator for dialysis
CN209690234U (en) * 2018-12-29 2019-11-26 华中科技大学同济医学院附属同济医院 Central venous catheter measuring device

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010050256A1 (en) * 1994-09-16 2001-12-13 Krivitski Nikolai M. Method and apparatus to measure blood flow and recirculation in hemodialysis shunts
CN1436087A (en) * 2000-06-15 2003-08-13 株式会社Jms Automatic blood dialyzer and dialyzing method
JP2008132256A (en) * 2006-11-29 2008-06-12 Unitika Ltd Vascular access catheter
EP2565904A1 (en) * 2011-09-05 2013-03-06 Commissariat à l'Énergie Atomique et aux Énergies Alternatives Method and apparatus for estimating a molecular mass parameter in a sample
CN104069557A (en) * 2013-03-28 2014-10-01 B·布莱恩·阿维图姆股份公司 Method of detecting recirculation in an arteriovenous shunt during ongoing hemodialysis and dialysis system
CN105096717A (en) * 2015-09-06 2015-11-25 杨荣利 Blood purification simulation and demonstration system
JP2017198938A (en) * 2016-04-28 2017-11-02 ニプロ株式会社 Puncture simulator for dialysis
CN209690234U (en) * 2018-12-29 2019-11-26 华中科技大学同济医学院附属同济医院 Central venous catheter measuring device

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