CN109758521A - A kind of male health-care liquid medicine - Google Patents

A kind of male health-care liquid medicine Download PDF

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CN109758521A
CN109758521A CN201711057249.6A CN201711057249A CN109758521A CN 109758521 A CN109758521 A CN 109758521A CN 201711057249 A CN201711057249 A CN 201711057249A CN 109758521 A CN109758521 A CN 109758521A
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radix
liquid medicine
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kidney
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林敬山
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Abstract

Invention provides a kind of male health-care liquid medicine, it is made of following parts by weight Chinese herb: Radix Codonopsis, Radix Angelicae Sinensis, Cortex Eucommiae, cortex cinnamomi, pilose antler, the root bark of tree peony, chrysanthemum, Poria cocos, radix rehmanniae preparata, Rhizoma Atractylodis Macrocephalae, mountain cornel, fructus lycii, psoralea corylifolia, Herba Epimedii, Semen Cuscutae, Radix Ophiopogonis, cynomorium songaricum, Morinda officinalis, Herba Cistanches, thizoma curculiginis, radix achyranthis bidentatae, teasel root, monkshood, raspberry, faenum graecum, fragrant-flowered garlic, safflower, white wine composition, first increase drug by its curative effect of medication with the method that steeping in wine wine steams, progress liquid medicine processing is blended in after drying to filter within 60 days up to liquid medicine finished product, all medicines share has tonifying kidney and strengthening yang, green blood tonifying Qi, invigorating the spleen is aid digestion, it clears liver and supports purpose function to deficiency syndrome of the lung shortness of breath, the male of insomnia forgetfulness has significant improvement result.

Description

A kind of male health-care liquid medicine
Technical field
The invention belongs to health-care medicated field, it is specifically a kind of for male's deficiency syndrome of the lung shortness of breath, insomnia forgetfulness and The male health-care liquid medicine of proposition.
Background technique
Wine is known as the title of " length of hundred medicines ", by the liquid medicine of the Chinese medicine to keep fit and healthy and wine " molten " Yu Yiti, not only preparation side Just, pharmacological property is stable, safely and effectively, and because alcohol is a kind of good semi-polarity organic solvent, Chinese medicine it is various effectively at Divide and be all soluble in wherein, wine assisting drug, wine help medicine gesture and gives full play to its effect, improve curative effect.
According to Traditional Chinese medical theory, predominantly internal organs are in disorder the reason of deficiency syndrome of the lung shortness of breath, insomnia forgetfulness, especially the heart Warm sun function and the enriching yin function of kidney cannot coordinate, deficiency of qi and blood, imbalance of yin and yang etc., existing male health-care liquid medicine, mostly due to Excessive yang-tonifying causes yang-energy excessively prosperous, and often irascibility rises, qi depression to blood stasis, causes cardiovascular disease, hearing lowers, memory subtracts It moves back, alopecia etc., therefore for the male for tasting insomnia forgetfulness and is not suitable for.
Summary of the invention
Technical problem to be solved by the present invention lies in provide a kind of male health-care liquid medicine, be by following parts by weight Medicine raw material composition: Radix Codonopsis, Radix Angelicae Sinensis, Cortex Eucommiae, cortex cinnamomi, pilose antler, the root bark of tree peony, chrysanthemum, Poria cocos, radix rehmanniae preparata, Rhizoma Atractylodis Macrocephalae, mountain cornel, fructus lycii, Psoralen Rouge, Herba Epimedii, Semen Cuscutae, Radix Ophiopogonis, cynomorium songaricum, Morinda officinalis, Herba Cistanches, thizoma curculiginis, radix achyranthis bidentatae, teasel root, monkshood, raspberry, faenum graecum, fragrant-flowered garlic Son, safflower, white wine composition, first increase drug by its curative effect of medication with the method that steeping in wine wine steams, carry out liquid medicine are blended in after drying It processes and filters within 60 days up to liquid medicine finished product, all medicines share has that tonifying kidney and strengthening yang, green blood tonifying Qi, invigorating the spleen is aid digestion, clears liver and supports purpose Function has significant improvement result to the male to deficiency syndrome of the lung shortness of breath, insomnia forgetfulness.
A kind of male health-care liquid medicine, it is characterised in that: be made of following parts by weight Chinese medicine material:
5-15 parts of Radix Codonopsis, 6-10 parts of Radix Angelicae Sinensis, 5-15 parts of Cortex Eucommiae, 7-12 parts of cortex cinnamomi, 1-5 parts of pilose antler, 7-12 parts of the root bark of tree peony, chrysanthemum 5-15 parts, 2-6 parts of Poria cocos, 10-15 parts of radix rehmanniae preparata, 6-10 parts of Rhizoma Atractylodis Macrocephalae, cornel 10-15 parts of mountain, 5-15 parts of fructus lycii, 10-15 parts of psoralea corylifolia, 10-15 parts of Herba Epimedii, 6-10 parts of Semen Cuscutae, Radix Ophiopogonis 6-10 part, 12-15 parts of cynomorium songaricum, 6-9 parts of Morinda officinalis, 10-15 parts of Herba Cistanches, 6-9 parts of thizoma curculiginis, 7-12 parts of radix achyranthis bidentatae, 6-10 parts of teasel root, 6-9 parts of monkshood, 5-15 parts of raspberry, 7-12 parts of faenum graecum, the sub- 10-15 of fragrant-flowered garlic Part, 5-8 parts of safflower, 2500-3000 parts of white wine.
A kind of male health-care liquid medicine, it is characterised in that: be made of following parts by weight Chinese medicine material:
It is 10 parts of Radix Codonopsis, 8 parts of Radix Angelicae Sinensis, 10 parts of Cortex Eucommiae, 9 parts of cortex cinnamomi, 3 parts of pilose antler, 9 parts of the root bark of tree peony, 10 parts of chrysanthemum, 5 parts of Poria cocos, ripe 12 parts of ground, 8 parts of Rhizoma Atractylodis Macrocephalae, 12 parts of mountain cornel, 10 parts of fructus lycii, 12 parts of psoralea corylifolia, 12 parts of Herba Epimedii, 8 parts of Semen Cuscutae, 8 parts of Radix Ophiopogonis, cynomorium songaricum 14 parts, 7 parts of Morinda officinalis, 12 parts of Herba Cistanches, 7 parts of thizoma curculiginis, 9 parts of radix achyranthis bidentatae, 8 parts of teasel root, 7 parts of monkshood, 10 parts of raspberry, faenum graecum 9 Part, fragrant-flowered garlic sub 12 parts, 6 parts of safflower, 2500-3000 parts of white wine.
Preparation method:
(1) Radix Codonopsis, Radix Angelicae Sinensis, Cortex Eucommiae, cortex cinnamomi, the root bark of tree peony, Poria cocos, radix rehmanniae preparata, Rhizoma Atractylodis Macrocephalae, cynomorium songaricum, Morinda officinalis, Herba Cistanches, thizoma curculiginis, ox Knee, psoralea corylifolia, teasel root, monkshood, raspberry, faenum graecum, fragrant-flowered garlic pick only be placed in casserole be added it is 200 parts soaking in Chinese liquor 1 small When after 1 hour of upper pot Steam by water bath stand dry it is spare;
(2) pilose antler is picked to be placed in casserole to stand for Steam by water bath 10 minutes after addition 1 hour of 50 parts of soaking in Chinese liquor only and be dried It is spare;
(3) mountain cornel, fructus lycii, Radix Ophiopogonis pick be placed on only 1 hour of 100 parts of soaking in Chinese liquor is added in casserole after Steam by water bath half it is small When stand dry it is spare;
(4) safflower, chrysanthemum, Herba Epimedii, Semen Cuscutae, which pick, was placed in casserole only after addition 1 hour of 100 parts of soaking in Chinese liquor Steam by water bath 15 minutes standings are dried spare;
(5) standings all in above-mentioned steps are finally dried spare drug to mix, binds in gauze, is placed in remaining It is filtered after being impregnated 60 days in white wine up to liquid medicine finished product.
Chinese medicine material pharmacology and pharmacological property in present invention application is as follows:
Radix Codonopsis: it is sweet in flavor, it is mild-natured;Returns spleen, lung channel;Matter moistens gas and has strengthening the spleen and tonifying the lung, nourishing qi and blood promotes the production of body fluid, and cures mainly taste Weakness, anorexia and loose stool, fatigue and weakness, the deficiency syndrome of the lung are breathed with cough, shortness of breath lazyness speech, spontaneous perspiration, and blood deficiency chlorosis is thirsty.Enhance passive protective physical fitness, drop Low blood pressure, blood-nourishing, tonifying middle-Jiao and Qi, treatment gastric ulcer, treatment diabetes.
Radix Angelicae Sinensis: sweet in flavor;It is pungent;It is bitter;It is warm-natured;Return liver;The heart;The spleen channel;Antianaemics;Emmenagogue;Anodyne;
[effect] enriches blood;Promoting blood circulation;Menstruction regulating and pain relieving;Moisturizing dryness and lubricating intestine
The all cards of [curing mainly] deficiency of blood;Irregular menstruation;Menostasis;Dysmenorrhea;Abdominal mass knot is poly-;Metrorrhagia and metrostaxis;Asthenia cold abdominalgia;Flaccidity syndrome and arthralgia syndrome;Skin fiber crops Wood;Intestines are dry and shit is difficult;Weight after dysentery with bloody stool;Ulcer sores;Injury from falling down.
Cortex Eucommiae: it is sweet in flavor, it is warm-natured.Tonify the liver and kidney, strengthen muscles and bones, coordinating Chong and Conception Vessels, strengthen meridian and miscarriage prevention the effect of.Kidney yang can be treated Pain in waist and lower extremities caused by void or aching and limp inability, born of the same parents' tire caused by liver- qi invasion is not solid, the wet equal diseases of itching of scrotum.
Cortex cinnamomi: acrid-sweet flavor, property heat enter kidney, spleen, bladder meridian;There are supplementing Yuanyang, warming spleen and stomach, removing internal cold, coronary circulation-promoting pain-relieving and antidiarrheal The effect of;It cures mainly the Yang-function insufficiency of kidneyzang, cold weak pulse of limb, yang depletion collapse, abdominal pain diarrhoea, cold hernia, waist and knee crymodynia, close through cassia bark (side) The diseases such as lump in the abdomen, negative subcutaneous ulcer streamer, the floating heat in the upper and cold in the lower more of empty sun.
1. warming kidney and enhancing body: for the chilly of the insufficiency of the kidney yang, limb cold, waist and knee crymodynia, also can be used for empty asthma, the gas of the failure of the kidney in receiving air It is inverse
2. middle benefit gas dispelling cold: for the stomachache with cool feeling and abdominal pain diarrhea of deficiency-cold in spleen and stomach, often with rhizoma zingiberis, monkshood with use
3. antalgic: energy warm promoting blood circulation, eliminating cold to stop pain, for dysmenorrhea, limbs pain caused by cold obstruction causing qi stagnation.
Pilose antler: [nature and flavor] are sweet, salty, temperature.[channel tropism] returns kidney, Liver Channel.[function] invigorating kidney yang, mends marrow, and punching is adjusted in strengthening the bones and muscles Appoint, torr sore poison.[curing mainly] kidney deficiency, dizziness, deafness, mesh be dark, impotence, spermatorrhoea, uterus cold infertile, it is thin it is thin, mind is tired, chilly, spinal column are cold Bitterly, muscles and bones impotence, metrorrhagia and metrostaxis leukorrhagia, negative subcutaneous ulcer is not held back and the diseases such as prolonged illness is deficient.
The root bark of tree peony: refer to cortex moutan;Bitter, pungent, slightly cold, return heart, liver and kidney channel have clearing heat and cooling blood, activate blood circulation and disperse blood clots, reducing the asthenic fever etc. Effect.
Chrysanthemum: i.e. day lily, mild-natured, sweet in flavor, slight bitter return liver,spleen,kidney to pass through;There are reducing fever and causing diuresis, removing toxicity for detumescence, hemostasis removes It is tired of, wide chest diaphragm, blood-nourishing calming the liver, Li Shui is promoted lactation, the wide chest of relieving sore-throat, eliminating dampness and heat, stimulate the secretion of milk and other effects;It is tired to cure mainly dizziness and tinnitus, palpitaition The illnesss such as bored, hot urination, oedema, hemorrhoidal hemorrhage.Day lily also has hemostasis, detumescence, eases pain, promotes lactation, stomach invigorating and tranquilizing the mind Function can treat hepatitis, jaundice, the various diseases such as lower blood, flu, dysentery of defecating.
Poria cocos: property slightly sweet flavor is flat, enters the heart, lung, the spleen channel.With eliminating dampness and diuresis, the effect of strengthening the spleen and stomach, antitoxic heart-soothing and sedative.
Radix rehmanniae preparata: [pharmacological property] is sweet, tepor.Return liver and kidney channel.
[effect] enriches blood yin-nourishing, life essence-filling, marrow-benefitting.
Rhizoma Atractylodis Macrocephalae: [meridian distribution of property and flavor] hardship, sweet, warm.Returns spleen, stomach meridian.
[major function] strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, miscarriage prevention.For spleen eating less, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, Oedema, spontaneous perspiration, threatened abortion.
Mountain cornel, that is, Fructus Corni: its is mild-natured, sweet in flavor, sour, function nourishing liver and kidney, astringing YIN to stop sweating emergency treatment of collapse, is nourishing kidney yin key medicine, main It is used for syndrome of yin deficiency of liver and kidney, suitable for soreness and weakness of waist and knees caused by liver and kidney deficiency, dizziness and tinnitus, impotence, spermatorrhea, frequent urination, void The diseases such as apogee sweating.Match together with the nourishing kidney yins drugs such as mountain cornel and fructus lycii radix rehmanniae preparata with food, kidney-yang nourishing herbal cuisine can be made into, it is right Hypertension, neurasthenia are treated, hypogona dism has good therapeutic effect.
Fructus lycii: sweet and neutral.Wolfberry leaf: bitter, sweet;It is cool in nature.
Function: fructus lycii: nourishing the liver, nourshing kidney, moistening lung.Wolfberry leaf: qi-restoratives strengthening the essence, heat-clearing improving eyesight.
Psoralea corylifolia: nature and flavor are pungent, bitter, temperature;Return kidney, the spleen channel.There is warming kidney and enhancing yang, receive gas, the effect of antidiarrheal.It is lost for impotence Essence, enuresis frequent micturition, waist and knee crymodynia, kidney deficiency characterized by dyspnea, Diarrhoea;External application curing vitiligo, the diseases such as alopecia areata.
Herba Epimedii:
[meridian distribution of property and flavor] acrid, sweet, warm.Return liver and kidney channel.
[major function] kidney-replenishing, strengthening bones and muscles, dispelling wind and dampness.For impotence and seminal emission, muscles and bones impotence, rheumatic arthralgia is numb to arrest Contraction;Climacteric hypertension.
Semen Cuscutae:
Acrid flavour, sweet, slightly warm in nature;Liver,kidney,spleen is returned to pass through;Gas and property are slow, and can float can sink;With tonifying kidney and benefiting sperm, nourish the liver to improve visual acuity, Tire is consolidated in invigorating the spleen;Pain in the loins tinnitus is cured mainly, impotence and seminal emission is quenched one's thirst, and infertility, enuresis incontinence, under the turbid belt, the head is dim, deficiency of food diarrhea, Threatened abortion.
Radix Ophiopogonis: nature,taste and action: sweet, slight bitter, cool, Yin-nourishing and body fluid promoting, moistening lung to arrest cough, relieving restlessness and restlessness.Cure mainly consumption of body fluid caused by febrile disease, the heart Tired, thirsty, dry throat lung heat, cough, pulmonary tuberculosis.
Cynomorium songaricum: " smell " sweet, warm, it is nontoxic.
" curing mainly " big tonifying yin gas, benefiting essence-blood, benefit stool.Empty people's dry feces person, that eats can be for desert cistanche, and cook congee Mi Jia.No Constipation person does not use (shake is prosperous).Nourishing the muscle and tendon is moisturized, it is weak to control impotence.
Morinda officinalis: nature and flavor: Xin Gan;Temperature.
Channel tropism: Liver Channel;Kidney channel.
Function: it tonifies the kidney and support yang;It strengthens muscles and bones;Dispelling wind and eliminating dampness.
The major functions: impotence due to deficiency of the kidney;Premature ejaculation of passing out semen;Abdomen crymodynia;Urinary incontinence;Uterus cold infertile;Wind-cold-dampness arthralgia;Soreness and weakness of waist and knees; Rheumatism limb gas.
Herba Cistanches: it is sweet in flavor, warm-natured, there is tonifying kidney and strengthening yang, Tianjing Busuiye medicinal, enriching the blood to restore normal menstruation, happy color macrobiosis and other effects.Kidney tonifying Sun;Benefiting essence-blood;Ease constipation road.Main decline of kidney-YANG;The impotence of asthenia of essence and blood;Spermatorrhea;Gonorrhoea;The frequent micturition heeltap;Pain in the loins flaccidity of lower limbs;Tinnitus mesh Flower;Menstruation is spread out the phase;Fertility;Dry constipation of intestines
Thizoma curculiginis: have the function of tonifying the kidney and support yang, benefiting essence-blood, strengthening the bones and muscles and promoting circulation of blood detumescence, be mainly used for the insufficiency of the kidney yang, impotence The illnesss such as spermatorrhea, consumptive disease internal injury and arthralgia and myalgia.
Radix achyranthis bidentatae: bitter in taste, acid, it is mild-natured, the major functions: radix achyranthis bidentatae-original plant soreness of waist and knee joint;Flaccidity and weakness of the lower limbs;Amenorrhea due to stagnation of blood;Dysmenorrhea; Postpartum abdominal pain due to blood stasis;Abdominal mass;Placenta retension;Heat gonorrhea;Blood strangury;Traumatic injury;Carbuncle swells dislikes sore;Abscess of throat.
Teasel root: it is warm-natured, it is bitter, pungent, have nourishing liver and kidney, strengthening the bones and muscles, continuous injured, only metrorrhagia and metrostaxis the effect of, can be used for treating waist and knee Aching and limp, rheumatic arthralgia, metrorrhagia and metrostaxis, vaginal bleeding during pregnancy, the illness of injury from falling down.
Monkshood: meridian distribution of property and flavor: pungent, sweet, big heat;It is toxic.It belongs to the heart, kidney, spleen channel.
Function: recuperating depleted yang, mends fire supporing yang, eliminating cold to stop pain." for the first product of recuperating depleted yang medicine "
The major functions: it is used for exessive yin refusing yang, loss of YANG due to profuse perspiration, and inverse, cold weak pulse of limb of fainting of vomiting and diarrhoea, trusted subordinate's crymodynia, cold dysentery, tinea pedis oedema, Wind-cold-dampness arthralgia, impotence, palace cold, cold of insufficiency type vomiting and diarrhea, cold sensation of the genitalia oedema, deficiency of yang diseases caused by external factors, the disease of negative subcutaneous ulcer sore and all chronic diseases.
Raspberry:
[channel tropism]: liver;Kidney channel
[effect classification]: astringent medicinal;Kidney-reinforcing drug [effect]: liver-kidney tonifying, astringent sperm contracting urine, improving eyesight;[curing mainly] impotence and premature ejaculation, Emission and spermatorrhea, uterus cold infertile, leukorrhagia is thin, frequent micturition incontinence of urine, eyes dim, poliosis.Its demand does not occur with season obvious Variation.
Faenum graecum: warm-natured, bitter.Warming kidney and enhancing yang, eliminating cold to stop pain.Kidney-replenishing, dispellieg cold and dampness.Cold hernia is controlled, abdomen coerces turgor, cold-dampness Tinea pedis, the kidney deficiency soreness of waist, impotence.
Fragrant-flowered garlic: nature and flavor are pungent;It is sweet;It is warm-natured
Channel tropism: liver;Kidney channel is major function: tonify the liver and kidney;Establishing-Yang controlling nocturnal emission with astringent drugs.Main impotence due to deficiency of the kidney;Soreness and weakness of waist and knees;Spermatorrhea;Frequent micturition; Turbid urine;Leukorrhagia is thin.
Safflower: warm-natured, acrid flavour, blood circulation, removing blood stasis and acesodyne.For menostasis, dysmenorrhea, lochia, abdominal mass lump in the abdomen, bruise Damage.
White wine: warm-natured, toil sweet in flavor has cold dispelling gas, helps the efficacy of a drug, blood circulation and channel invigorating, improves a poor appetite, eliminating fatigue, resisting cold The effect of refreshing oneself.
Specific embodiment:
Embodiment 1, formula:
Radix Codonopsis 5g, Radix Angelicae Sinensis 6g, Cortex Eucommiae 5g, cortex cinnamomi 7g, pilose antler 1g, root bark of tree peony 7g, chrysanthemum 5g, Poria cocos 2g, radix rehmanniae preparata 10g, Rhizoma Atractylodis Macrocephalae 6g, mountain cornel 10g, fructus lycii 5g, psoralea corylifolia 10g, Herba Epimedii 10g, Semen Cuscutae 6g, Radix Ophiopogonis 6g, cynomorium songaricum 12g, Morinda officinalis 6g, Herba Cistanches 10g, thizoma curculiginis 6g, radix achyranthis bidentatae 7g, teasel root 6g, monkshood 6g, raspberry 5g, faenum graecum 7g, the sub- 10g of fragrant-flowered garlic, safflower 5g, white wine 2500g;
Preparation method:
(1) Radix Codonopsis, Radix Angelicae Sinensis, Cortex Eucommiae, cortex cinnamomi, the root bark of tree peony, Poria cocos, radix rehmanniae preparata, Rhizoma Atractylodis Macrocephalae, cynomorium songaricum, Morinda officinalis, Herba Cistanches, thizoma curculiginis, ox Knee, psoralea corylifolia, teasel root, monkshood, raspberry, faenum graecum, fragrant-flowered garlic pick is placed on addition 1 hour of 200g soaking in Chinese liquor in casserole only 1 hour standing of upper pot Steam by water bath is dried spare afterwards;
(2) pilose antler pick only be placed in casserole be added 1 hour of 50g soaking in Chinese liquor after Steam by water bath 10 minutes stand dry it is standby With;
(3) mountain cornel, fructus lycii, Radix Ophiopogonis pick be placed on only 1 hour of 100g soaking in Chinese liquor is added in casserole after Steam by water bath half it is small When stand dry it is spare;
(4) safflower, chrysanthemum, Herba Epimedii, Semen Cuscutae pick only be placed in casserole be added 1 hour of 100g soaking in Chinese liquor after every 15 minutes standings of water steaming are dried spare;
(5) standings all in above-mentioned steps are finally dried spare drug to mix, binds in gauze, is placed in remaining It is filtered after being impregnated 60 days in white wine up to liquid medicine finished product.
Embodiment 2, formula: Radix Codonopsis 10g, Radix Angelicae Sinensis 8g, Cortex Eucommiae 10g, cortex cinnamomi 9g, pilose antler 3g, root bark of tree peony 9g, chrysanthemum 10g, Poria cocos 5g, radix rehmanniae preparata 12g, Rhizoma Atractylodis Macrocephalae 8g, mountain cornel 12g, fructus lycii 10g, psoralea corylifolia 12g, Herba Epimedii 12g, Semen Cuscutae 8g, Radix Ophiopogonis 8g, cynomorium songaricum 14g, Morinda officinalis 7g, Herba Cistanches 12g, thizoma curculiginis 7g, radix achyranthis bidentatae 9g, teasel root 8g, monkshood 7g, raspberry 10g, faenum graecum 9g, fragrant-flowered garlic 12g, safflower 6g, white wine 2800g.
Preparation method is same as Example 1.
Embodiment 3, formula: Radix Codonopsis 15g, Radix Angelicae Sinensis 10g, Cortex Eucommiae 15g, cortex cinnamomi 12g, pilose antler 5g, root bark of tree peony 12g, chrysanthemum 15g, Poria cocos 6g, radix rehmanniae preparata 15g, Rhizoma Atractylodis Macrocephalae 10g, mountain cornel 15g, fructus lycii 15g, psoralea corylifolia 15g, Herba Epimedii 15g, Semen Cuscutae 10g, Radix Ophiopogonis 10g, Cynomorium songaricum 15g, Morinda officinalis 9g, Herba Cistanches 15g, thizoma curculiginis 9g, radix achyranthis bidentatae 12g, teasel root 10g, monkshood 9g, raspberry 15g, faenum graecum 12g, The sub- 15g of fragrant-flowered garlic, safflower 8g, white wine 3000g.
Preparation method is same as Example 1.
Acute toxicity test
Application mouse carries out acute toxicity testing and shows: Mouse oral stomach-filling Traditional Chinese medicinal liquor of the invention, raw in 488.8g Under medicine/kg dosage, there is light activity reduction in mouse after administration, restores within 1 hour or so normal, 7 days is observed continuously after administration, nothing One animal dead, overall health of patients, diet, to take the photograph water, urine and body weight increase normal, the results showed that Mouse oral fills The maximum dosage-feeding of stomach Chinese materia medica preparation of the invention is 488.8g crude drug/kg/d (50 > 488.8g crude drug of LD/kg).The present invention The daily total amount of clinical medication of Traditional Chinese medicinal liquor be 0.1g crude drug/kg/d;By batheroom scale, intragastric administration on mice Traditional Chinese medicinal liquor of the invention Dosis tolerata is 4888 times of clinical patient.Prompt the acute toxicity low, clinical application safety.
Long term toxicity test:
SD rat is selected, gives the Traditional Chinese medicinal liquor of the invention of various concentration (18.0,6.0,2.0g crude drug/kg), daily Stomach-filling is primary, and continuous 90 days, 1/2 animal (half male and half female) was killed in each group work in 24 hours after the last administration, remaining 1/2 animal continues to see Work is killed after examining 2 weeks.Appearance, general behavior, the food intake, weight change that animal is observed during test, 90 days and drug withdrawal 2 after administration Zhou Jinhang hematology (RBC, HB, granulophilocyte, PLT, CT, WBC and classification) and blood biochemical (AST, ALT, ALP, Glu, BUN, Crea, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, the index checkings such as Histopathology.Test result table Bright: liquid medicine of the present invention is good in high, medium and low dosage group animal general state, appearance signs, behavioral activities, food-intake and weight Increase variation without exception;Three dosage groups and control group hematological examination, blood biochemistry, urine biochemistry are normal Range, without significant difference between group;Each group main organs histopathological examination is shown no obvious abnormalities.After These parameters are discontinued 2 weeks Also change is had no.This test medication capacity for liquor is respectively the 180 of clinical medicine dose, 60,20 times, of the invention according to test result Chinese materia medica preparation has no significant effect rat in administration in high, medium and low three dosage (18.0,6.0,2.0g crude drug/kg) continuous 90 days, Without specific toxicity target organ and sensitive indicator, convalescence observation also has no retardance toxic reaction, prompts Chinese medicine of the invention The dose safety of liquid medicine clinical application is higher.
Animal local stimulation test:
The allergic reaction on guinea pigs of Traditional Chinese medicinal liquor of the present invention.The result shows that: skin anaphylactic test, high dose group 0.8g (medicinal powder)/kg, low dose group 0.1g (medicinal powder)/kg, be respectively equivalent to 20 times of quasi- clinical people's dosage [0.04g (medicinal powder)/kg], It 2.5 times, through percutaneous drug delivery, is showed no animal and generates allergy;Rectal application irritation test high dose group 5.0g (medicinal powder)/ Kg, low dose group 3.2g (medicinal powder)/kg are respectively equivalent to 125,80 times of quasi- clinical people's dosage, observe before the deadline Mucous membrane of rectum without congested, oedema phenomena such as, histopathologic examination's no significant difference compared with blank control group has no appearance Apparent irritative response, its overall health of patients of the Some Animals of every group of retention, weight, breathing, circulation, central nervous system and four Limb activity etc., equal Non Apparent Abnormality reaction.
Experimental study of the present invention:
1 object and method
1.1 object in April, 2015 in March, 2017 see and treat patients male's deficiency syndrome of the lung shortness of breath, insomnia forgetfulness, cardiovascular disease, Hearing attenuating, failure of memory, alopecia, patient 200 of functional erectile dysfunction, are randomly divided into 5 groups, every group of 40 people.
1.2 research embodiment groups are formulated liquid medicine using the traditional chinese medicine composition of the invention, do not use doctor trained in Western medicine base therapy, pass through Negotiate with patient, after obtaining patient's agreement, signature informed consent form and hand-in-glove.
1.2.1 two Chinese medicine health type liquid medicine salable on the market is respectively adopted in totally two groups of control group,
2 groups of oral medicinal liquors of 3 groups of embodiment and control, divide 3 doses, 10ml/ agent/day, a month as a treatment course takes January After check.
1.3 observation index
Five groups of patients after taking medicine January,
1.4 statistical analysis
Using SPSS13.0 statistics software, data analysis is carried out.
2 evaluations/treatment results
2.1 efficacy assessment standard
Cure: Clinical symptom and sign disappears substantially, and functional activity restores normal;
Improve: Clinical symptom and sign major part disappears, and functional activity returns to normal;
Invalid: Clinical symptom and sign does not disappear, and functional activity is without substantially changeing.
2.2 medication group treatment results statistics:
Therefore a kind of male sexual disorder of the present invention etc. has remarkable result.
All above-mentioned this intellectual properties of primarily implementation, there is no this new products of implementation of setting limitation other forms And/or new method.Those skilled in the art will utilize this important information, above content modification, to realize similar execution feelings Condition.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above described is only a preferred embodiment of the present invention, being not that the invention has other forms of limitations, appoint What those skilled in the art changed or be modified as possibly also with the technology contents of the disclosure above equivalent variations etc. Imitate embodiment.But without departing from the technical solutions of the present invention, according to the technical essence of the invention to above embodiments institute Any simple modification, equivalent variations and the remodeling made, still fall within the protection scope of technical solution of the present invention.

Claims (2)

1. a kind of male health-care liquid medicine, it is characterised in that: be made of following parts by weight Chinese medicine material:
5-15 parts of Radix Codonopsis, 6-10 parts of Radix Angelicae Sinensis, 5-15 parts of Cortex Eucommiae, 7-12 parts of cortex cinnamomi, 1-5 parts of pilose antler, 7-12 parts of the root bark of tree peony, chrysanthemum 5-15 Part, 2-6 parts of Poria cocos, 10-15 parts of radix rehmanniae preparata, 6-10 parts of Rhizoma Atractylodis Macrocephalae, cornel 10-15 parts of mountain, 5-15 parts of fructus lycii, 10-15 parts of psoralea corylifolia, excessive sheep 10-15 parts of the leaves of pulse plants, 6-10 parts of Semen Cuscutae, Radix Ophiopogonis 6-10 part, 12-15 parts of cynomorium songaricum, 6-9 parts of Morinda officinalis, 10-15 parts of Herba Cistanches, thizoma curculiginis 6-9 parts, 7-12 parts of radix achyranthis bidentatae, 6-10 parts of teasel root, 6-9 parts of monkshood, 5-15 parts of raspberry, 7-12 parts of faenum graecum, fragrant-flowered garlic it is 10-15 parts sub-, 5-8 parts of safflower, 2500-3000 parts of white wine;
Preparation method:
(1) Radix Codonopsis, Radix Angelicae Sinensis, Cortex Eucommiae, cortex cinnamomi, the root bark of tree peony, Poria cocos, radix rehmanniae preparata, Rhizoma Atractylodis Macrocephalae, cynomorium songaricum, Morinda officinalis, Herba Cistanches, thizoma curculiginis, radix achyranthis bidentatae, Psoralea corylifolia, teasel root, monkshood, raspberry, faenum graecum, fragrant-flowered garlic, which pick, to be placed in casserole only after addition 1 hour of 200 parts of soaking in Chinese liquor 1 hour standing of upper pot Steam by water bath is dried spare;
(2) pilose antler pick only be placed in casserole be added 1 hour of 50 parts of soaking in Chinese liquor after Steam by water bath 10 minutes stand dry it is spare;
(3) mountain cornel, fructus lycii, Radix Ophiopogonis pick be placed on only 1 hour of 100 parts of soaking in Chinese liquor is added in casserole after Steam by water bath half an hour it is quiet Set dry it is spare;
(4) safflower, chrysanthemum, Herba Epimedii, Semen Cuscutae pick is placed in casserole water proof after addition 1 hour of 100 parts of soaking in Chinese liquor only Steam 15 minutes stand dry it is spare;
(5) standings all in above-mentioned steps are finally dried spare drug to mix, binds in gauze, is placed in remaining white wine Middle immersion is filtered after 60 days up to liquid medicine finished product.
2. a kind of male health-care liquid medicine according to claim 1, it is characterised in that: be by following parts by weight Chinese medicine material group At:
10 parts of Radix Codonopsis, 8 parts of Radix Angelicae Sinensis, 10 parts of Cortex Eucommiae, 9 parts of cortex cinnamomi, 3 parts of pilose antler, 9 parts of the root bark of tree peony, 10 parts of chrysanthemum, 5 parts of Poria cocos, radix rehmanniae preparata 12 Part, 8 parts of Rhizoma Atractylodis Macrocephalae, 12 parts of mountain cornel, 10 parts of fructus lycii, 12 parts of psoralea corylifolia, 12 parts of Herba Epimedii, 8 parts of Semen Cuscutae, 8 parts of Radix Ophiopogonis, cynomorium songaricum 14 Part, 7 parts of Morinda officinalis, 12 parts of Herba Cistanches, 7 parts of thizoma curculiginis, 9 parts of radix achyranthis bidentatae, 8 parts of teasel root, 7 parts of monkshood, 10 parts of raspberry, 9 parts of faenum graecum, Fragrant-flowered garlic son 12 parts, 6 parts of safflower, 2500-3000 parts of white wine.
CN201711057249.6A 2017-11-01 2017-11-01 A kind of male health-care liquid medicine Pending CN109758521A (en)

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CN115721697A (en) * 2022-07-14 2023-03-03 谢天水 Kidney-tonifying and yang-strengthening medicinal liquor and preparation method thereof

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Application publication date: 20190517