CN109758400A - A kind of anti-chap bacteriostatic deodorizing foot liniment of moisturizing and preparation method thereof - Google Patents

A kind of anti-chap bacteriostatic deodorizing foot liniment of moisturizing and preparation method thereof Download PDF

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Publication number
CN109758400A
CN109758400A CN201910226853.XA CN201910226853A CN109758400A CN 109758400 A CN109758400 A CN 109758400A CN 201910226853 A CN201910226853 A CN 201910226853A CN 109758400 A CN109758400 A CN 109758400A
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extract
chap
water
liniment
foot
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王德星
王钟浩
王尤伦
王亚红
陈威威
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Fuzhou Yinghe Daily Chemicals Co Ltd
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Fuzhou Yinghe Daily Chemicals Co Ltd
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Abstract

The invention discloses anti-chap bacteriostatic deodorizing foot liniments of a kind of moisturizing and preparation method thereof, in particular to technical field of skin care.Formula of the invention has selected tea extract, Fructus Kochiae extract, Fructus Rubi extract, phellodendron extract, Baical Skullcap root P.E, shrubby sophora extract, common cnidium fruit P.E, cooperate vitamin E, urea, lanolin, chapped skin, chap bleeding can be improved rapidly, subcutaneous moisture and function are balanced, bacterial fungus, antipruritic removing stink are inhibited, mitigate affected part pain, damaged tissues are repaired, promote foot split, chap, gradually rehabilitation of peeling, being easy to use, it is good to imitate.Reasonable recipe of the present invention, by dermal application and Chinese medicine Transdermal absorption, moisturizing profit, anti-chap, antipruritic bacteriostatic deodorizing, nursing pedal skin are convenient, practical, effect is good.

Description

A kind of anti-chap bacteriostatic deodorizing foot liniment of moisturizing and preparation method thereof
Technical field
The invention belongs to technical field of skin care, the anti-chap bacteriostatic deodorizing foot liniment of specifically a kind of moisturizing and its preparation Method.
Background technique
Pedal skin chap, decortication are mainly in heel, sole, toe head, damage deep mixed, some keratodermas increasing It is thick, it may appear that the symptoms such as pain.It followed by can be involved skin corium and subcutaneous tissue, there is obvious pain and shouting pain phenomenon.China has 35% Dry and cracked, chap, decortication patient there is lasting recurrence and fungal infection, not only cause foot peculiar smell, return walking and bring pole Big difficulty.Treatment method is outer wiping urea frost, vitamin E ointment, tannic acid ointment, imidazoles or Salicylic Acid Formulations etc. at present. These product functions are single, are used alone, and effect is bad, to be used in combination in the case where professional instructs, could obtain effect, separately Outer patient is again very inconvenient using so multi items simultaneously.
Tannic acid in tealeaves can restrain wound, can antiallergy.Fruit of summer cypress fresh breeze is antipruritic, cures mainly rubeola, eczema, scabies, skin Skin itch.Studies in China finds fruit of summer cypress flooding agent (1:3), in vitro to trichophyton schoenleini, microsporum audouini, iron The dermatophytes such as rust microsporum, ulotrichy microsporum, star-shaped nocardia have different degrees of inhibiting effect.It covers Basin contains gallic acid, raspberry acid, has inhibiting effect to staphylococcus, also has inhibiting effect to comma bacillus.Cortex Phellodendri contains There is alkaloid, (sonnei is removed to staphylococcus aureus, pneumococcus, corynebacterium diphtheriae, Streptococcus viridans, shigella dysenteriae Outside), hemolytic streptococcus, meningococcus, comma bacillus, bacillus anthracis all have a strong inhibitory effect;To hay bacillus, hundred Day cough bacillus, clostridium tetani also have inhibiting effect;Cortex Phellodendri decoction or preserved material have common pathogenic fungus different degrees of Inhibiting effect has stronger bacteriostasis to Cryptococcus neoformans and trichophyton purpureatum, acts on stronger than nystatin.Radix scutellariae tool There is wider antimicrobial spectrum, in vitro test has inhibiting effect to bacillus, coccus, also has effect to dermatophyte.Kuh-seng contains matrine (matrine) and sparteine (cytisine) etc., there is the benefits of clearing heat and promoting diuresis, antibacterial anti-inflammatory, expelling parasite, be commonly used for treatment skin scabies Itch.There is inhibition effect to a variety of fungies.Frutus cnidii controls mycotic infection and acute exudative skin disease, there is antifungic action.Dimension life Plain E is applied to prevention skin keratin, and prevention of inflammation dermatoses accelerate the healing of wound.Urea is a kind of good moisturizing Ingredient, it is present in the cuticula of skin, belongs to the main component of skin natural moisturizing factor NMF.For skin, Urea has effects that moisturizing and soft cutin, is usually used in moisturizing composition in the products such as facial mask, surfactant, cream, hand lotion Addition.Lanolin prevents breach to have special efficiency protection skin.When use effective component by dermal application and in Medicine Transdermal absorption, moisturizing profit, bacteriostatic deodorizing, promote wound healing at anti-chap, nurse pedal skin.
Formula of the invention has selected tea extract, Fructus Kochiae extract, Fructus Rubi extract, phellodendron extract, Huang A kind of reed mentioned in ancient books extract, shrubby sophora extract, common cnidium fruit P.E, cooperate vitamin E, urea, lanolin, can improve rapidly chapped skin, Chap bleeding, balances subcutaneous moisture and function, inhibits bacterial fungus, and antipruritic removing stink mitigates affected part pain, repairs impaired group It knits, promotes foot split, chap, gradually rehabilitation of peeling, being easy to use, it is good to imitate.Reasonable recipe of the present invention, by dermal application and Chinese medicine Transdermal absorption, moisturizing profit, anti-chap, antipruritic bacteriostatic deodorizing, nursing pedal skin are convenient, practical, effect is good.
Summary of the invention
The purpose of the present invention is to provide anti-chap bacteriostatic deodorizing foot liniments of a kind of moisturizing and preparation method thereof.
To achieve the above object, the present invention adopts the following technical scheme that:
A kind of anti-chap bacteriostatic deodorizing foot liniment of moisturizing, the foot liniment are made of following weight percent:
0.5% ~ 1.5% tea extract
0.5% ~ 1.5% Fructus Kochiae extract
0.5% ~ 1.5% Fructus Rubi extract
0.5% ~ 1.5% phellodendron extract
0.5% ~ 1.5% Baical Skullcap root P.E
0.5% ~ 1.5% shrubby sophora extract
0.5% ~ 1.5% common cnidium fruit P.E
0.1% ~ 0.5% vitamin E
1% ~ 5% urea
Remaining complements to 100% with cream matrix.
Preferably, the cream matrix is made of following weight fraction: stearic acid 4-5g, glycerin monostearate 1-2g, Liquid paraffin 2-3g, albolene 0.2-0.8g, lanolin 1-3g, triethanolamine 0.1-0.3g, distilled water add to 40.0g.
Preferably, the cream matrix is prepared by the following method: weigh in proportion stearic acid, glycerin monostearate, Liquid paraffin, albolene and lanolin are oily phase, are set in evaporating dish, in keeping warm 60-90 DEG C of heating melting in water-bath, are separately compared Example weighs triethanolamine and distilled water is set in beaker, in being also heated to warm 60-90 DEG C or so in water-bath, water phase is obtained, in isothermal It is lower slowly to pour into water phase in oily phase, and in being stirred continuously in water-bath to the semi-solid that is creamy white, then be stirred at room temperature to Cream matrix is made in close condense.
A kind of preparation method of the anti-chap bacteriostatic deodorizing foot liniment of the moisturizing, comprising the following steps:
(1) tealeaves, the fruit of summer cypress, raspberry, Cortex Phellodendri, radix scutellariae, kuh-seng, frutus cnidii are used into water heating extracting respectively, are added 10-15 times Measure water, with 200 mesh filter-cloth filterings after boiling extraction 2-3 hours, obtain tealeaves, the fruit of summer cypress, raspberry, Cortex Phellodendri, radix scutellariae, kuh-seng, The first time extracting solution of frutus cnidii;
(2) add 7-10 times into filter residue after filtering and measure water, refiltered after boiling extraction again 1.5-2.5 hours with 200 mesh filter clothes, Obtain second of extracting solution of tealeaves, the fruit of summer cypress, raspberry, Cortex Phellodendri, radix scutellariae, kuh-seng, frutus cnidii;
(3) merge filtrate twice and be concentrated under reduced pressure, gained Aqueous extracts are concentrated into 1 ~ 3 times of former plant weight, respectively obtain tealeaves Extract, Fructus Kochiae extract, Fructus Rubi extract, phellodendron extract, Baical Skullcap root P.E, shrubby sophora extract, frutus cnidii extract Object;
(4) weigh in proportion tea extract, Fructus Kochiae extract, Fructus Rubi extract, phellodendron extract, Baical Skullcap root P.E, Cream matrix is added after being uniformly mixed in shrubby sophora extract, common cnidium fruit P.E, vitamin E, urea, and foot is made after mixing Liniment.
Preferably, the temperature of the reduced pressure in step (3) is 60-110 DEG C.
The present invention has the advantages that formula of the invention has selected tea extract, Fructus Kochiae extract, raspberry to extract Object, phellodendron extract, Baical Skullcap root P.E, shrubby sophora extract, common cnidium fruit P.E cooperate vitamin E, urea, lanolin, can be fast Speed improves chapped skin, chap bleeding, balances subcutaneous moisture and function, inhibits bacterial fungus, and antipruritic removing stink mitigates affected part Pain repairs damaged tissues, promotes foot split, chap, gradually rehabilitation of peeling, being easy to use, it is good to imitate.Reasonable recipe of the present invention, By dermal application and Chinese medicine Transdermal absorption, moisturizing profit, anti-chap, antipruritic bacteriostatic deodorizing, nursing pedal skin, convenient, practical, Effect is good.
Specific embodiment
In order to be easy to understand the technical means, the creative features, the aims and the efficiencies achieved by the present invention, below will In conjunction with technical scheme in the embodiment of the invention is clearly and completely described in the embodiment of the present invention.
Embodiment 1
Weigh stearic acid 4g, glycerin monostearate 1g, liquid paraffin 2g, albolene 0.2g and lanolin 1g in proportion as oil Phase is set in evaporating dish, and in keeping warm 60 DEG C of heating meltings in water-bath, another ratio weighs triethanolamine 0.1g and sets in beaker, adds steaming After distilled water to 40g, in being also heated to 60 DEG C or so of temperature in water-bath, water phase is obtained.Water phase is slowly poured into oily phase under isothermal, And in being stirred continuously in water-bath to the semi-solid that is creamy white, then it is stirred at room temperature to close condense and cream matrix is made.By tea Leaf, the fruit of summer cypress, raspberry, Cortex Phellodendri, radix scutellariae, kuh-seng, frutus cnidii use water heating extracting respectively, and 10 times of amount water are added, boil extraction 2 With 200 mesh filter-cloth filterings after hour, obtain tealeaves, the fruit of summer cypress, raspberry, Cortex Phellodendri, radix scutellariae, kuh-seng, frutus cnidii first time mention Take liquid;After filtering into filter residue plus 7 times of amount water, boil refiltered after extracting 1.5 hours with 200 mesh filter clothes again, obtain tealeaves, The fruit of summer cypress, raspberry, Cortex Phellodendri, radix scutellariae, kuh-seng, frutus cnidii second of extracting solution;Merge filtrate twice and is depressurized at 60 DEG C Concentration, gained Aqueous extracts are concentrated into 1.5 times of former plant weight, respectively obtain tea extract, Fructus Kochiae extract, raspberry Extract, phellodendron extract, Baical Skullcap root P.E, shrubby sophora extract, common cnidium fruit P.E;Weigh in proportion tea extract 1%, Fructus Kochiae extract 1%, Fructus Rubi extract 1%, phellodendron extract 1%, Baical Skullcap root P.E 1%, shrubby sophora extract 1%, frutus cnidii mention Cream matrix is added after taking object 1%, vitamin E 0.3%, urea 3% to be uniformly mixed to 100%, foot is made after mixing and smears Agent.
Embodiment 2
Stearic acid 4.5g, glycerin monostearate 1.5g, liquid paraffin 2.5g, albolene 0.5g and lanolin are weighed in proportion 2g is oily phase, is set in evaporating dish, and in keeping warm 70 DEG C of heating meltings in water-bath, another ratio weighs triethanolamine 0.2g and sets beaker In, after adding distilled water to 40g, in being also heated to 70 DEG C or so of temperature in water-bath, obtain water phase.Water phase is slowly poured under isothermal In oily phase, and in being stirred continuously in water-bath to the semi-solid that is creamy white, then it is stirred at room temperature to close condense and cream base is made Matter.Tealeaves, the fruit of summer cypress, raspberry, Cortex Phellodendri, radix scutellariae, kuh-seng, frutus cnidii are used into water heating extracting respectively, 12 times of amount water are added, boil Boiling extract 2.5 hours after with 200 mesh filter-cloth filterings, obtain tealeaves, the fruit of summer cypress, raspberry, Cortex Phellodendri, radix scutellariae, kuh-seng, frutus cnidii First time extracting solution;Add 9 times of amount water after filtering into filter residue, is refiltered, obtained with 200 mesh filter clothes after boiling extraction again 2 hours To tealeaves, the fruit of summer cypress, raspberry, Cortex Phellodendri, radix scutellariae, kuh-seng, frutus cnidii second of extracting solution;Merge filtrate twice and at 70 DEG C Lower reduced pressure, gained Aqueous extracts are concentrated into 1.5 times of former plant weight, respectively obtain tea extract, Fructus Kochiae extract, Fructus Rubi extract, phellodendron extract, Baical Skullcap root P.E, shrubby sophora extract, common cnidium fruit P.E;Tealeaves extraction is weighed in proportion Object 0.5%, Fructus Kochiae extract 0.5%, Fructus Rubi extract 0.5%, phellodendron extract 0.5%, Baical Skullcap root P.E 0.5%, kuh-seng mention Cream matrix is added after taking object 0.5%, common cnidium fruit P.E 0.5%, vitamin E 0.1%, urea 1% to be uniformly mixed to 100%, Foot liniment is made after mixing.
Embodiment 3
Weigh stearic acid 5g, glycerin monostearate 2g, liquid paraffin 3g, albolene 0.8g and lanolin 3g in proportion as oil Phase is set in evaporating dish, and in keeping warm 80 DEG C of heating meltings in water-bath, another ratio weighs triethanolamine 0.2g and sets in beaker, adds steaming After distilled water to 40g, in being also heated to 80 DEG C or so of temperature in water-bath, water phase is obtained.Water phase is slowly poured into oily phase under isothermal, And in being stirred continuously in water-bath to the semi-solid that is creamy white, then it is stirred at room temperature to close condense and cream matrix is made.By tea Leaf, the fruit of summer cypress, raspberry, Cortex Phellodendri, radix scutellariae, kuh-seng, frutus cnidii use water heating extracting respectively, and 15 times of amount water are added, boil extraction 3 With 200 mesh filter-cloth filterings after hour, obtain tealeaves, the fruit of summer cypress, raspberry, Cortex Phellodendri, radix scutellariae, kuh-seng, frutus cnidii first time mention Take liquid;Add 10 times of amount water after filtering into filter residue, is refiltered after boiling extraction again 2.5 hours with 200 mesh filter clothes, obtain tea Leaf, the fruit of summer cypress, raspberry, Cortex Phellodendri, radix scutellariae, kuh-seng, frutus cnidii second of extracting solution;Merge filtrate twice and subtracts at 80 DEG C Pressure concentration, gained Aqueous extracts are concentrated into 3 times of former plant weight, respectively obtain tea extract, Fructus Kochiae extract, raspberry Extract, phellodendron extract, Baical Skullcap root P.E, shrubby sophora extract, common cnidium fruit P.E;Tea extract is weighed in proportion 1.5%, Fructus Kochiae extract 1.5%, Fructus Rubi extract 1.5%, phellodendron extract 1.5%, Baical Skullcap root P.E 1.5%, kuh-seng extract Cream matrix is added to 100% in object 1.5%, common cnidium fruit P.E 1.5%, vitamin E 0.5%, urea 5% after being uniformly mixed, mix Foot liniment is made after conjunction.
Embodiment 4
Stearic acid 4.8g, glycerin monostearate 1.7g, liquid paraffin 2.8g, albolene 0.6g and lanolin are weighed in proportion 2.7g is oily phase, is set in evaporating dish, and in keeping warm 85 DEG C of heating meltings in water-bath, another ratio weighs triethanolamine 0.2g and sets beaker In, after adding distilled water to 40g, in being also heated to 85 DEG C or so of temperature in water-bath, obtain water phase.Water phase is slowly poured under isothermal In oily phase, and in being stirred continuously in water-bath to the semi-solid that is creamy white, then it is stirred at room temperature to close condense and cream base is made Matter.Tealeaves, the fruit of summer cypress, raspberry, Cortex Phellodendri, radix scutellariae, kuh-seng, frutus cnidii are used into water heating extracting respectively, 14 times of amount water are added, boil Boiling extract 2.8 hours after with 200 mesh filter-cloth filterings, obtain tealeaves, the fruit of summer cypress, raspberry, Cortex Phellodendri, radix scutellariae, kuh-seng, frutus cnidii First time extracting solution;Add 9 times of amount water after filtering into filter residue, refiltered after boiling extraction again 2.3 hours with 200 mesh filter clothes, Obtain second of extracting solution of tealeaves, the fruit of summer cypress, raspberry, Cortex Phellodendri, radix scutellariae, kuh-seng, frutus cnidii;Merge filtrate twice and 75 It is concentrated under reduced pressure at DEG C, gained Aqueous extracts are concentrated into 2.8 times of former plant weight, respectively obtain tea extract, the fruit of summer cypress extracts Object, Fructus Rubi extract, phellodendron extract, Baical Skullcap root P.E, shrubby sophora extract, common cnidium fruit P.E;Tealeaves is weighed in proportion Extract 1.2%, Fructus Kochiae extract 1.2%, Fructus Rubi extract 1.2%, phellodendron extract 1.2%, Baical Skullcap root P.E 1.2%, hardship Cream matrix is added extremely after being uniformly mixed in conopsea extraction 1.2%, common cnidium fruit P.E 1.2%, vitamin E 0.3%, urea 4% 100%, foot liniment is made after mixing.
Foot liniment obtained presses 2015 " cosmetics safety technical specifications " through the invention, carries out acute skin irritation Property test (rabbit), multiple skin irritation test (rabbit), bacteriostatic test and hot and cold stability test etc., test as follows:
One, stability test
1, test basis: QB/T1857-2013
2, test result:
3, conclusion
This test proves the compound regulation of stability of foot liniment produced by the present invention.
Two, bacteriostatic test
1, test equipment
(1) staphylococcus aureus (ATCC 6538), Escherichia coli (8099), Candida albicans (ATCC 10231)
(2) (5 mm diameter circular Xinhua No.1 qualitative filter paper pieces set 120 after pressuresteam sterilization is handled to antibacterial agent carrier DEG C 2h is dried, saved backup)
(3) equipment needed for viable bacteria is cultivated
(4) micropipettor (5 μ l of μ l ~ 50)
(5) vernier caliper
2, test procedure
(1) preparation of test sample: taking product 1g, adds sterile distilled water 5g, is mixed even spare at test sample.It takes sterile and drying Filter paper.Every 20 μ l of dropwise addition test sample, then lies against filter paper in clean sterilized petri dishes, uncaps and sets incubator (37 DEG C) In dry it is spare.
(2) sterile dry filter paper piece, every 20 μ l of dropwise addition sterile distilled water, after dry the preparation of negative control print: are taken It is spare.
(3) inoculation of test organisms: dipping concentration with sterile cotton swab is 500000cfu/ml ~ 5000000cfu/ml test Bacteria suspension is uniformly smeared 3 times in nutrient agar planar surface.It is every smear 1 time, plate rotation, finally by cotton swab around Plate edge is smeared one week.Plate is covered, drying at room temperature 5min is set.
(4) test sample print is placed with: test is placed with 1 microbiological contamination plate every time, and each plate is placed with 4 test prints, and 1 Negative control print, totally 5.It is placed with aseptic nipper coupongs in planar surface.At a distance of 25mm or more between each print center, Periphery with plate is at a distance of 15mm or more.After being placed with, with the light pressure-like piece of aseptic nipper, it is made to be tightly attached to planar surface.It covers Plate, sets 37 DEG C of incubators, and culture 16h ~ 18h observes result.Simultaneously with the diameter (including patch) of vernier caliper measurement antibacterial ring size Record.Test is repeated 3 times.
3, evaluation method
(1) judgement of bacteriostasis: inhibition zone diameter is greater than 7mm person, has been judged to bacteriostasis.Inhibition zone diameter is less than or waits In 7mm person, it is judged to no bacteriostasis.
(2) 3 repetition tests have bacteriostasis result person, are judged to qualification.
(3) negative control group should be generated without antibacterial ring size.Otherwise test is invalid.
4, result
5, conclusion
This test proves that foot liniment produced by the present invention has staphylococcus aureus, Escherichia coli, Candida albicans There is fungistatic effect.
Three, skin irritation test 1(rabbit)
1, it test method: is operated by the acute skin irritation test in 2015 " cosmetics health specifications ".
2, test result:
3, conclusion: this test proves that foot liniment produced by the present invention is nonirritant.
Four, skin irritation test 2(rabbit)
1, it test method: is operated by the multiple skin irritation test in 2015 " cosmetics health specifications ".
2, test result:
3, conclusion: this test proves that foot liniment produced by the present invention is nonirritant.
Foot liniment obtained presses 2015 " cosmetics safety technical specifications " through the invention, carries out acute skin irritation Property test (rabbit), multiple skin irritation test (rabbit), bacteriostatic test and hot and cold stability test etc., it was demonstrated that its safety is real With effective.
Although above the present invention is described in detail with a general description of the specific embodiments, On the basis of the present invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Cause This, these modifications or improvements, fall within the scope of the claimed invention without departing from theon the basis of the spirit of the present invention.

Claims (5)

1. a kind of anti-chap bacteriostatic deodorizing foot liniment of moisturizing, which is characterized in that the foot liniment is by following weight percent Than composition:
0.5% ~ 1.5% tea extract
0.5% ~ 1.5% Fructus Kochiae extract
0.5% ~ 1.5% Fructus Rubi extract
0.5% ~ 1.5% phellodendron extract
0.5% ~ 1.5% Baical Skullcap root P.E
0.5% ~ 1.5% shrubby sophora extract
0.5% ~ 1.5% common cnidium fruit P.E
0.1% ~ 0.5% vitamin E
1% ~ 5% urea
Remaining complements to 100% with cream matrix.
2. the anti-chap bacteriostatic deodorizing foot liniment of a kind of moisturizing according to claim 1, which is characterized in that the cream base Matter is made of following weight fraction: stearic acid 4-5g, glycerin monostearate 1-2g, liquid paraffin 2-3g, albolene 0.2- 0.8g, lanolin 1-3g, triethanolamine 0.1-0.3g, distilled water add to 40.0g.
3. the anti-chap bacteriostatic deodorizing foot liniment of a kind of moisturizing according to claim 1 or 2, which is characterized in that the cream White matrix is prepared by the following method: weighing stearic acid, glycerin monostearate, liquid paraffin, albolene and sheep in proportion Hair rouge is oily phase, is set in evaporating dish, and in keeping warm 60-90 DEG C of heating melting in water-bath, another ratio weighs triethanolamine and distillation Water is set in beaker, in being also heated to warm 60-90 DEG C or so in water-bath, obtains water phase, and water phase is slowly poured into oily phase under isothermal In, and in being stirred continuously in water-bath to the semi-solid that is creamy white, then be stirred at room temperature to close condense and cream matrix is made.
4. a kind of preparation method of the anti-chap bacteriostatic deodorizing foot liniment of moisturizing according to claim 1, which is characterized in that The following steps are included:
(1) tealeaves, the fruit of summer cypress, raspberry, Cortex Phellodendri, radix scutellariae, kuh-seng, frutus cnidii are used into water heating extracting respectively, are added 10-15 times Measure water, with 200 mesh filter-cloth filterings after boiling extraction 2-3 hours, obtain tealeaves, the fruit of summer cypress, raspberry, Cortex Phellodendri, radix scutellariae, kuh-seng, The first time extracting solution of frutus cnidii;
(2) add 7-10 times into filter residue after filtering and measure water, refiltered after boiling extraction again 1.5-2.5 hours with 200 mesh filter clothes, Obtain second of extracting solution of tealeaves, the fruit of summer cypress, raspberry, Cortex Phellodendri, radix scutellariae, kuh-seng, frutus cnidii;
(3) merge filtrate twice and be concentrated under reduced pressure, gained Aqueous extracts are concentrated into 1 ~ 3 times of former plant weight, respectively obtain tealeaves Extract, Fructus Kochiae extract, Fructus Rubi extract, phellodendron extract, Baical Skullcap root P.E, shrubby sophora extract, frutus cnidii extract Object;
(4) weigh in proportion tea extract, Fructus Kochiae extract, Fructus Rubi extract, phellodendron extract, Baical Skullcap root P.E, Cream matrix is added after being uniformly mixed in shrubby sophora extract, common cnidium fruit P.E, vitamin E, urea, and foot is made after mixing Liniment.
5. a kind of preparation method of the anti-chap bacteriostatic deodorizing foot liniment of moisturizing according to claim 4, which is characterized in that The temperature of reduced pressure in step (3) is 60-110 DEG C.
CN201910226853.XA 2019-03-25 2019-03-25 A kind of anti-chap bacteriostatic deodorizing foot liniment of moisturizing and preparation method thereof Pending CN109758400A (en)

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CN111012694A (en) * 2019-12-30 2020-04-17 华熙生物科技股份有限公司 Hyaluronic acid-containing spray for repairing and moisturizing soles and preparation method thereof

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CN105997989A (en) * 2016-05-17 2016-10-12 上海通用药业股份有限公司 Urea and vitamin E cream for treating hand and foot rahagades and rahagades caused by keratotic tinea hand or pedis
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CN108420981A (en) * 2018-05-30 2018-08-21 武汉润禾生物医药有限公司 A kind of antibacterial ointment and preparation method thereof for treating skin tinea of feet and hands

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CN111012694A (en) * 2019-12-30 2020-04-17 华熙生物科技股份有限公司 Hyaluronic acid-containing spray for repairing and moisturizing soles and preparation method thereof

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