CN109730076A - A kind of bactericidal composition and its application containing difenoconazole and pyrimethanil - Google Patents
A kind of bactericidal composition and its application containing difenoconazole and pyrimethanil Download PDFInfo
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- CN109730076A CN109730076A CN201910122355.0A CN201910122355A CN109730076A CN 109730076 A CN109730076 A CN 109730076A CN 201910122355 A CN201910122355 A CN 201910122355A CN 109730076 A CN109730076 A CN 109730076A
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Abstract
The invention discloses a kind of bactericidal composition containing difenoconazole and pyrimethanil, effective component is difenoconazole probenazole and pyrimethanil, and the weight ratio of difenoconazole and pyrimethanil is 15:1~1:10, preferably 10:1~1:5, further preferred 5:1~1:3, still further preferably 3:1~1:2.Can also containing allow in Pesticide Science using with acceptable auxiliary material.Dosage form can be wettable powder, suspending agent, aqueous emulsion, water dispersible granules, microemulsion.The application of bactericidal composition of the invention in prevention and treatment fruit, vegetable storage phase disease, the disease are selected from gray mold, anthracnose, ring spot, penicilliosis.Bactericidal composition of the invention, effective component difenoconazole, the mechanism of action of pyrimethanil are entirely different, compounding has obvious synergistic function, can be improved to the pathogen of Botrytis cinerea, Target spot pathogen, anthrax bacteria bactericidal activity, delay the generation of fungicide resistance, keep the corrosion-resistanting fresh-keeping effect of fruit and vegetable food more significant, improves the economic value of fruit and vegetable food.
Description
Technical field
The present invention relates to a kind of bactericidal composition containing difenoconazole and pyrimethanil, and its in prevention and treatment water fruits and vegetables storage
Application in hiding phase disease, belongs to pesticide control technical field.
Background technique
Fresh agricultural products storage logistics is the continuity of agricultural production, keeps its excellent quality and freshness is people's pursuit
One of important goal, postharvest decay is rotten must to be solved the problems, such as during fresh agricultural products storage, logistics transportation.According to system
Meter, the loss late in developed country's veterinary antibiotics product transporting procedures less than 5%, and the annual loss late in China be up to 25%~
30%.The pathogen of Botrytis cinerea (Botrytis cinerea), anthrax bacteria (Colletotrichum gloeosporiorides) are
Cause the important pathogen that postharvest fruit and vegetable rots, grape, strawberry, peach, apple, pears, tomato, cucumber, eggplant, fragrant-flowered garlic can be endangered
The various fruits such as dish, vegetables not only cause to seriously endanger and the important disease of storage period in fruits and vegetables growth period.
Prevented and treated in production the pathogen of Botrytis cinerea, the common chemical bactericide of anthrax bacteria have carbendazim, iprodione, pyrimethanil,
Prochloraz etc., but the pathogen of Botrytis cinerea, anthrax bacteria have the characteristics that breeding is fast, hereditary variation is big, grade of fit is high, and continuous use is same
One medicament is also easy to produce drug resistance, brings extreme difficulties to prevention and treatment, only controls fruits and vegetables by increasing dosing or times for spraying and produces
Product rot, and are either unfavorable for improving anti-corrosion effect still to guarantee fruits and vegetables quality all.Meanwhile as people are to food
The residual toxicity of the concern of product safety problem, fungicide is increasingly taken seriously, and it is few to find safer, wide spectrum, dosage
Germ killing drugs combination, reduces the usage amount of chemical bactericide, delays the generation of drug resistance, be current postharvest fruit and vegetable anti-corrosive fresh-keeping
Research hotspot and the technical problem to be solved in the present invention.
Difenoconazole is the interior suction wide-spectrum bactericide that safety is relatively high in triazole bactericidal agent, difenoconazole
The mechanism of action is to be able to suppress the biosynthesis of the ergosterol of fungi, has protection and therapeutic effect, wide sterilization spectrum, lasting period
Long feature is widely used in the crops such as fruit tree, vegetables, can effectively prevent the diseases such as scab, anthrachose of grape and white rot.
Pyrimethanil belongs to pyrimidine fungicides fungicide, is a kind of efficient, the less toxic fungicide for preventing and treating gray mold, has interior
Inhale conduction and fumigation action, each position in plant can be passed to after application rapidly, by inhibit germ invasive enzyme secretion to
It prevents germ from infecting, thoroughly kills germ.It with other fungicide no interactions resistances, and uses at low temperature, there still have to be very good
Protection and therapeutic effect.For preventing and treating crop gray mold and black spot of fruit tree, spot defoliation etc..
Difenoconazole or pyrimethanil is used alone to be prevented and be controlled fruit, vegetable storage phase gray mold, anthrax
Disease, ring spot, penicilliosis effect are undesirable.Currently, there is not yet by the relevant report of difenoconazole and Pyrimethanil compositional.
Summary of the invention
For the above-mentioned prior art, the present invention provides a kind of bactericidal composition containing difenoconazole and pyrimethanil, and
Its application in prevention and treatment fruit, vegetable storage phase disease (especially gray mold, anthracnose, ring spot, penicilliosis).
The present invention is achieved by the following technical solutions:
A kind of bactericidal composition containing difenoconazole and pyrimethanil, effective component are difenoconazole probenazole and phonetic mould
The weight ratio of amine, difenoconazole and pyrimethanil be 15:1~1:10, preferably 10:1~1:5, further preferred 5:1~1:3, then
Further preferred 3:1~1:2.
Further, in the bactericidal composition containing difenoconazole and pyrimethanil, can contain allows in Pesticide Science
Using with acceptable auxiliary material.
Further, the bactericidal composition containing difenoconazole and pyrimethanil is grouped as by the group of following parts by weight
: difenoconazole 1%~60%, pyrimethanil 1%~60%, surplus are to allow in Pesticide Science using auxiliary with acceptable
Material.
Allow to be selected from solvent, dispersing agent, diffusant, disintegrating agent, cream using with acceptable auxiliary material in the Pesticide Science
Agent, adsorbent, stabilizer, wetting agent, defoaming agent, antifreeze etc. or other stabilizations for facilitating effective component drug effect and hair
That waves allows using auxiliary agent.
The bactericidal composition containing difenoconazole and pyrimethanil can use processing method system well known in the prior art
Standby any one dosage form used at suitable agricultural production, preferred dosage form are as follows: wettable powder, suspending agent, aqueous emulsion, water dispersion
Granula, microemulsion.
Bactericidal composition containing difenoconazole and pyrimethanil of the invention, in prevention and treatment fruit, vegetable storage phase disease
Application.The disease is selected from gray mold, anthracnose, ring spot, penicilliosis.
Further, when preventing and treating the pathogen of Botrytis cinerea, the weight ratio of both difenoconazole and pyrimethanil is with 10:1~1:5
It is preferred, more preferably, 2:1 is best by 5:1~1:1；When preventing and treating Botryosphaeria berengeriana f. sp, the weight ratio of both difenoconazole and pyrimethanil
It is preferred with 5:1~1:5, more preferably, 3:1 is best by 3:1~1:3；When preventing and treating apple anthrax bacteria, difenoconazole and pyrimethanil two
The weight ratio of person is preferred with 5:1~1:3, and more preferably, 3:1 is best by 3:1~1:2.
Bactericidal composition containing difenoconazole and pyrimethanil of the invention, can be provided in the form of finished product preparation, can also be with
Unit dose form provides, and using preceding direct mixing, is then watered mixing and is made into required concentration, the dipping before water fruits and vegetables enter freezer
Or it is spraying, it is put in storage after drying.
Bactericidal composition containing difenoconazole and pyrimethanil of the invention, effective component difenoconazole, pyrimethanil
The mechanism of action is entirely different, and inventor (difenoconazole and pyrimethanil is used in combination, indoors screening and field by test
On the basis of test, the anti-corrosion effect to storage period gray mold, anthracnose, ring spot, penicilliosis is measured, there is apparent synergy
Effect) discovery, difenoconazole is compounded with pyrimethanil, has the advantage that (1) apparent synergistic function, it should
Composition improve single dose to the pathogen of Botrytis cinerea, Target spot pathogen, anthrax bacteria bactericidal activity；(2) reduce chemical bactericide
Usage amount and access times, reduce use cost, the quality safety of food can be improved；(3) medicament of different role mechanism
It is used in combination, the generation of fungicide resistance can be delayed；(4) corrosion-resistanting fresh-keeping effect of fruit and vegetable food is more significant, greatly prolongs
The shelf life of fruit and vegetable food, improves the economic value of fruit and vegetable food.
The various terms and phrase that the present invention uses are with well known to a person skilled in the art general senses.The term referred to
With phrase if any meaning inconsistent with common art-recognized meanings, that the present invention of being subject to is stated.
Detailed description of the invention
The pharmacodynamic results of Fig. 1: 30% difenoconazole pyrimethanil microemulsion prevention and treatment storage period apple anthracnose.
Specific embodiment
Below with reference to embodiment, the present invention is further illustrated.However, the scope of the present invention is not limited to following realities
Apply example.One of skill in the art, can be to the present invention it is understood that under the premise of without departing substantially from the spirit and scope of the present invention
Carry out various change and modification.
The present invention carries out general and/or specific description to the material and test method arrived used in test.Though
So many materials and operating method used in purpose are it is known in the art that still the present invention is still herein to realize the present invention
It is described in detail as far as possible.
Instrument involved in following embodiments, reagent, material etc. are unless otherwise noted existing in the prior art
Conventional instrument, reagent, material etc., can be obtained by regular commercial sources.Experimental method involved in following embodiments, inspection
Survey method etc. is unless otherwise noted existing routine experiment method in the prior art, detection method etc..
It tests difenoconazole and Pyrimethanil compositional and (indoor toxicity test) is studied to the preventive and therapeutic effect of disease
One, reagent agent: difenoconazole, pyrimethanil raw medicine.By raw medicine acetone solution, and it is made into 10000 μ g/mL's
Emulsifier Tween-80 is added with 0.2% volume fraction in mother liquor, stored at 4 DEG C in refrigerator it is spare, with sterile water when use
It is diluted to debita spissitudo.
Two, for trying pathogen: Pathogen Botrytis cinerea Pers. ex of Garlic Sprout (Botrytis cinerea), Botryosphaeria berengeriana f. sp
(Botryosphaeria dothidea), apple anthrax bacteria (Colletotrichum gloeosporiorides).
Three, indoor toxicity test method: matched using mycelial growth rate method p-phenylene methyl cyclic-azole, pyrimethanil and the two difference
Toxicity test is carried out than combination, and calculates co-toxicity coefficient (CTC).
Single agent virulence determination method: reagent agent (including difenoconazole, pyrimethanil) is first configured to 5 concentration gradients
(difenoconazole: 2.0,1.0,0.5,0.25,0.125mg/kg；Pyrimethanil: 2.0,1.0,0.5,0.25,0.125mg/kg),
By pathogen in 26 DEG C of preculture 3d in PDA culture medium, with the punch of diameter 7mm on the same circumference close to colony edge
It is beatened to take bacteria cake, is inoculated on the culture medium flat plate containing different agents concentration, every ware is a piece of, is placed in culture in 26 DEG C of insulating boxs
3d measures the colony growth diameter of each processing with crossing method, is control with clear water, and every concentration processing is repeated 4 times.Measure bacterium
Radial linear increment is fallen, determines the inhibiting rate that medicament grows bacterium colony.Pass through mycelia growth inhibition probability value and drug concentration
Linear regression analysis between logarithm finds out each medicament to concentration (EC in effective inhibition of bacterial strain50Value).
Mixture joint toxicity measuring:, will be for the difenoconazole of mixture, pyrimethanil point on the basis of single dose toxicity test
It An not its EC50That 15:1,10:1,5:1,3:1,2:1,1:1,1:2,1:3,1:5,1:10 is respectively set is total for example by volume for value dosage
10 proportions, being configured to final mass concentration by different ratio is 1.0,0.5,0.25,5 0.125,0.0625mg/kg series
The drug containing PDA culture medium of concentration, the inhibiting rate that measurement medicament grows mycelia.Every processing (every every concentration level of bacterial strain) repeats 4
It is secondary.By the linear regression analysis between mycelia growth inhibition probability value and drug concentration logarithm, Mixed Pharmacy is found out to bacterium
Concentration EC in effective inhibition of strain50Value and CTC value, using the PDA culture medium of not adding medicine as control.
Four, data statistic analysis
Test data is for statistical analysis by Microsoft Excel 2013, DPS data processing work platform, calculates
The EC of every kind of medicament out50Value, 95% confidence limit.The co-toxicity coefficient that mixed agent is calculated using Sun Yunpei's Method (1960), according to total poison
The synergistic effect of coefficient magnitude evaluation mixed agent.
Each medicament inhibiting rate is calculated according to the following formula:
Inhibit growth rate (%)=[(control antibacterial circle diameter-processing antibacterial circle diameter)/(control antibacterial circle diameter -5mm
Punch diameter)] × 100；
Inhibit growth rate (%)=[(control colony diameter-processing colony diameter)/(control colony diameter-bacteria cake diameter)]
×100；
Toxicity index TI=(standard agent EC50/ reagent agent EC50)×100；
Mixed agent actual toxicity index ATI=(standard agent EC50/ mixture preparation EC50)×100；
(PA and PB are respectively mixed agent to TI × PB of TI × PA+ single dose B of mixed agent theoretical toxicity index TTI=single dose A
The percentage composition of middle effective component)；
Theoretical toxicity index TTI × 100 of the actual toxicity index ATI/ mixed agent of co-toxicity coefficient CTC=mixed agent；
Synergistic effect judgement: CTC >=120 have synergistic effect；80 < CTC < 120 are summation action；CTC≤80 are
Antagonism.
Five, result and analysis: as shown in Table 1 to Table 3.
1 difenoconazole of table is with pyrimethanil different proportion mixture to the toxicity test result of the pathogen of Botrytis cinerea
Seen from table 1, difenoconazole and pyrimethanil and its mixture preparation have the pathogen of Botrytis cinerea and inhibit to make well
With, when wherein the proportion of difenoconazole and pyrimethanil is between 10:1~1:5, to for try pathogen co-toxicity coefficient exist
120 or more, show that both compositions have good synergistic function under this proportion, especially proportion is in 5:1~1:2
Between, EC50The EC that value is used alone significantly lower than difenoconazole and pyrimethanil50Value, mixture preparation is to the pathogen of Botrytis cinerea
Inhibitory activity significantly improves, and synergistic effect is more significant.
2 difenoconazole of table is with pyrimethanil different proportion mixture to the toxicity test result of Botryosphaeria berengeriana f. sp
As can be seen from Table 2, difenoconazole, pyrimethanil and its mixture preparation, have Botryosphaeria berengeriana f. sp and inhibit well
Effect when wherein the proportion of difenoconazole and pyrimethanil is between 5:1~1:5, exists to the co-toxicity coefficient for trying pathogen
120 or more, show that both compositions have good synergistic function under this proportion, especially proportion is in 3:1~1:1
Between, the EC of mixture preparation50The EC that value is used alone significantly lower than difenoconazole and pyrimethanil50Value, synergistic effect is more
Significantly.
3 difenoconazole of table is with pyrimethanil different proportion mixture to the toxicity test result of apple anthrax bacteria
Seen from table 3, difenoconazole and pyrimethanil and its mixture preparation have apple anthrax bacteria and inhibit well
Effect when wherein the proportion of difenoconazole and pyrimethanil is between 5:1~1:3, exists to the co-toxicity coefficient for trying pathogen
120 or more, show that both compositions have good synergistic function under this proportion, especially proportion is in 3:1~1:2
Between, the EC of mixture preparation50The EC that value is used alone significantly lower than difenoconazole and pyrimethanil50Value, synergistic effect is more
Significantly.
1 20% difenoconazole pyrimethanil aqueous emulsion of embodiment
Group is grouped as following (each component is by weight percentage):
The preparation method comprises the following steps: above-mentioned each active constituent, various auxiliary agents are sufficiently mixed in proportion, make to be dissolved into homogeneous oil phase,
Under high-speed stirred, oil is mutually mixed with water, obtains 20% difenoconazole pyrimethanil aqueous emulsion.
2 27% difenoconazole pyrimethanil water dispersible granule of embodiment
Group is grouped as following (each component is by weight percentage):
The preparation method comprises the following steps: above-mentioned each active constituent, calcium lignosulfonate, wetting agent, disintegrating agent, filler is abundant in proportion
Mixing, is crushed to 5 μm of partial size through airslide disintegrating mill, obtains female powder, be granulated after female powder and neopelex are sufficiently mixed,
Drying, sieving, so that 27% difenoconazole pyrimethanil water dispersible granule be made.
3 36% difenoconazole pyrimethanil of embodiment
Group is grouped as following (each component is by weight percentage):
The preparation method comprises the following steps: above-mentioned each active constituent, various auxiliary agents and water are sufficiently mixed uniformly in proportion, investment is sanded
Machine is ground to 5 μm of partial size, and 36% difenoconazole pyrimethanil is made.
4 40% difenoconazole pyrimethanil wettable powder of embodiment
Group is grouped as following (each component is by weight percentage):
The preparation method comprises the following steps: above-mentioned each active constituent, various auxiliary agents and filler are sufficiently mixed uniformly in proportion, mixture warp
40% difenoconazole pyrimethanil wettable powder is made in ultra-fine pulverizer disintegrating.
5 30% difenoconazole pyrimethanil microemulsion of embodiment
Group is grouped as following (each component is by weight percentage):
The preparation method comprises the following steps: above-mentioned each active constituent, various auxiliary agents are sufficiently mixed in proportion, make to be dissolved into homogeneous oil phase,
Under high-speed stirred, oil is mutually mixed with water, obtains 30% difenoconazole pyrimethanil microemulsion.
Application example 1:30% difenoconazole pyrimethanil microemulsion prevents and treats the research of storage period apple anthracnose
On October 22nd, 2017, kind was Fuji in the Qufu City Wu villages and small towns apple orchard Wu Cun, and selection nothing is rotted, without machinery wound
Apple carry out leaching fruit test.Apple is immersed to each chemicals treatment (30% difenoconazole pyrimethanil microemulsion 1200 respectively
Again, 800 times, 500 times；50% 600 times of carbendazol wettable powder；43% 1500 times of tebuconazole suspension concentrates) and clear water control in
(30% difenoconazole pyrimethanil microemulsion is prepared by embodiment 5), leaching fruit time are 30s, are subsequently placed in field tree lower berth
It dries in the shade in the sterilizing filter paper of pad.Then transport Shandong Fruit-tree Inst. back, the pre-cooling in freezer (1.0 ± 1.0 DEG C of temperature)
For 24 hours, 4 repetitions of every processing, 50 apples of every repetition are put into PE freshness protection package, and plastics fruit packaging can be had enough to meet the need by being then neatly put into
In case, one repetition of every case, totally 192 case, is finally putting into freezer (1.0 ± 1.0 DEG C of temperature) and is stored.15d after storage,
A case is taken out in each repetition of 30d, 45d, 60d respectively, carries out fruit rotting rate investigation.Processing method is same as above under 20 DEG C of room temperature.
Drug effect statistical analysis technique: pharmacy control efficacy is calculated according to the following formula；It is poor that the new multipole of Duncan is carried out using DPS software
Examine its otherness (P≤0.05).
a.
b.
As a result as shown in table 4 (Fig. 1) (note: in table 4,5, each extension rate refers to quality multiple for solid dosage forms,
For liquid dosage form, refer to volume multiple).
The pharmacodynamic results of 4 30% difenoconazole pyrimethanil microemulsion of table prevention and treatment storage period apple anthracnose
As shown in Table 4, it is cold after fruit processing is soaked after 30% 800 times of difenoconazole pyrimethanil microemulsion, 500 times are adopted
Rotting rate under the conditions of hiding when Apples 60d is substantially less than 600 times of 50% carbendazol wettable powder of comparison medicament, 43% penta
The rotting rate of 1500 times of azoles alcohol suspending agent is significantly better than other each processing to the control efficiency of apple anthracnose.Under room temperature,
When 25d is investigated, 30% 800 times of difenoconazole pyrimethanil microemulsion, 500 times of processing are aobvious to the control efficiency of apple anthracnose
It writes better than other each processing.Therefore, 30% difenoconazole pyrimethanil microemulsion leaching fruit processing apple, inhibition were stored after adopting
The generation of apple anthrax bacteria in journey improves the commodity value of fruit to extend storage period.
Application example 2:36% difenoconazole pyrimethanil prevents and treats the gray mold research of storage period garlic stems
On May 4th, 2017 is tested in Jinxiang County town Yu Shan dedicated freezer of peasant household's garlic stems.Before garlic stems harvesting storage, in
1500 times of 36% difenoconazole pyrimethanil (preparation of embodiment 3), 1200 times, 800 times, 25% prochloraz aqueous emulsion
250 times, clear water control in dipping garlic stems tongue fur tip 30s, after draining away the water be put in storage storage.It is cooled to -0.3 DEG C ± 0.2 DEG C in advance to garlic stems
Afterwards, silicon window bag storage, the normal freezer management together with other garlic stems are packed into.The experimental observation phase is 240 days.4 weights of each processing
It is multiple, 2 bags of each repetition (every bag of about 19kg garlic stems).It rots respectively at 90d, 120d, 150d, 180d, 210d, 240d investigation garlic stems
The indices such as rate, tongue fur tip color.
a.
b.
The results are shown in Table 5.
The pharmacodynamic test result of 5 36% difenoconazole pyrimethanil of table prevention and treatment garlic stems gray mold
As shown in Table 5, after slightly processing is soaked after 1200 times, 800 times of 36% difenoconazole pyrimethanil are adopted, garlic
A kind of sedge stores 240d control efficiency 87% or more, and tongue fur slightly color is normal, and no phenomenon of losing water shows good anti-corrosive fresh-keeping
Effect is significantly better than 250 times of 25% prochloraz aqueous emulsion.Therefore, it is outstanding using 36% difenoconazole pyrimethanil after garlic stems is adopted
Floating agent dipping, spraying tongue fur slightly, can significantly inhibit the generation of gray mold in garlic stems storage, to extend storage period, improve storage
Hide commodity.
Above-described embodiment is provided to those skilled in the art, how to implement and use to be advocated with full disclosure and description
Embodiment, rather than for limiting range disclosed herein.Obvious modification will to those skilled in the art
Within the scope of the appended claims.The all publications, patents and patent applications of this specification citation are incorporated by reference into this
Text, as these publications, patents and patent applications respectively show particularly and individually to be incorporated herein by reference.
Claims (10)
1. a kind of bactericidal composition containing difenoconazole and pyrimethanil, it is characterised in that: effective component is difenoconazole thiophene
The weight ratio of bacterium spirit and pyrimethanil, difenoconazole and pyrimethanil is 15:1~1:10.
2. the bactericidal composition according to claim 1 containing difenoconazole and pyrimethanil, it is characterised in that: the phenylate
The weight ratio of methyl cyclic-azole and pyrimethanil is 10:1~1:5, further preferred 5:1~1:3, still further preferably 3:1~1:2.
3. the bactericidal composition according to claim 1 or 2 containing difenoconazole and pyrimethanil, it is characterised in that: described
In bactericidal composition containing difenoconazole and pyrimethanil containing allow in Pesticide Science using with acceptable auxiliary material.
4. the bactericidal composition according to claim 3 containing difenoconazole and pyrimethanil, it is characterised in that: described to contain benzene
What ether methyl cyclic-azole and the bactericidal composition of pyrimethanil were grouped as by the group of following parts by weight: difenoconazole 1%~60%, it is phonetic mould
Amine 1%~60%, surplus be Pesticide Science in allow using with acceptable auxiliary material.
5. the bactericidal composition according to claim 3 or 4 containing difenoconazole and pyrimethanil, it is characterised in that: described
Allow in Pesticide Science using with acceptable auxiliary material be selected from solvent, dispersing agent, diffusant, disintegrating agent, emulsifier, adsorbent,
Stabilizer, wetting agent, defoaming agent, antifreeze etc. or other stabilizations for facilitating effective component drug effect and performance allow using
Auxiliary agent.
6. the bactericidal composition according to any one of claims 1 to 5 containing difenoconazole and pyrimethanil, feature exist
In: the dosage form of the bactericidal composition containing difenoconazole and pyrimethanil is wettable powder, suspending agent, aqueous emulsion, moisture
Shot agent or microemulsion.
7. the bactericidal composition according to claim 5 containing difenoconazole and pyrimethanil, it is characterised in that: the sterilization
The dosage form of composition is aqueous emulsion, is grouped as by the group of following weight percent:
Or: the dosage form of the bactericidal composition is water dispersible granules, is grouped as by the group of following weight percent:
Or: the dosage form of the bactericidal composition is suspending agent, is grouped as by the group of following weight percent:
Or: the dosage form of the bactericidal composition is wettable powder, is grouped as by the group of following weight percent:
Or: the dosage form of the bactericidal composition is microemulsion, is grouped as by the group of following weight percent:
8. the bactericidal composition according to any one of claims 1 to 7 containing difenoconazole and pyrimethanil is in prevention and treatment water fruit and vegetable
Application in dish storage period disease.
9. application according to claim 8, it is characterised in that: the disease is selected from gray mold, anthracnose, ring spot, blueness
Mildew.
10. application according to claim 8 or claim 9, it is characterised in that: when preventing and treating the pathogen of Botrytis cinerea, difenoconazole with
The weight ratio of both pyrimethanils is preferred with 10:1~1:5, and more preferably, 2:1 is best by 5:1~1:1；When preventing and treating Botryosphaeria berengeriana f. sp,
Difenoconazole and the weight ratio of both pyrimethanils are preferred with 5:1~1:5, and more preferably, 3:1 is best by 3:1~1:3；In prevention and treatment apple
When anthrax bacteria, difenoconazole and the weight ratio of both pyrimethanils are preferred with 5:1~1:3, and more preferably, 3:1 is best by 3:1~1:2.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5840730A (en) * | 1992-02-13 | 1998-11-24 | Novartis Corporation | Fungicidal compositions and method of controlling plant fungi |
| CN102783490A (en) * | 2012-06-25 | 2012-11-21 | 陈卫民 | Preparation method of seed coating agent for preventing sunflower black-stem disease |
| CN108260593A (en) * | 2016-12-30 | 2018-07-10 | 江苏龙灯化学有限公司 | A kind of bactericidal composition |
-
2019
- 2019-02-19 CN CN201910122355.0A patent/CN109730076A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5840730A (en) * | 1992-02-13 | 1998-11-24 | Novartis Corporation | Fungicidal compositions and method of controlling plant fungi |
| CN102783490A (en) * | 2012-06-25 | 2012-11-21 | 陈卫民 | Preparation method of seed coating agent for preventing sunflower black-stem disease |
| CN108260593A (en) * | 2016-12-30 | 2018-07-10 | 江苏龙灯化学有限公司 | A kind of bactericidal composition |
Non-Patent Citations (1)
| Title |
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| 张传博: "几种杀菌剂及其复配剂对草莓灰霉病菌的室内毒力测定", 《湖北农业科学》 * |
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Application publication date: 20190510 |
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