CN109674460A - A kind of the bougie structure and its packaging method of implanted micro sensor - Google Patents
A kind of the bougie structure and its packaging method of implanted micro sensor Download PDFInfo
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- CN109674460A CN109674460A CN201910120249.9A CN201910120249A CN109674460A CN 109674460 A CN109674460 A CN 109674460A CN 201910120249 A CN201910120249 A CN 201910120249A CN 109674460 A CN109674460 A CN 109674460A
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- circuit board
- conducting wire
- sensor
- pressure sensor
- titanium alloy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
- A61B5/02055—Simultaneously evaluating both cardiovascular condition and temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/03—Detecting, measuring or recording fluid pressure within the body other than blood pressure, e.g. cerebral pressure; Measuring pressure in body tissues or organs
- A61B5/031—Intracranial pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14503—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
- A61B5/6868—Brain
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Cardiology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Physiology (AREA)
- Optics & Photonics (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
Abstract
The present invention provides a kind of bougie structure of implanted micro sensor and its packaging methods, including titanium alloy shell, pressure sensor, temperature sensor, circuit board and the conducting wire being connect with external plug, circuit board uses flexible circuit board, welding substrate of the circuit board as sensor and conducting wire, pressure sensor and temperature sensor are located on circuit board, pressure sensor chip rest area on circuit board, pressure sensor pad, temperature sensor rest area, wire pad, which is arranged successively, to be in line, circuit board has the one side of electrode to be located at sensor setting face, one end that circuit board is provided with pressure sensor is located at the head of titanium alloy shell, conducting wire welded disc is located at the tail portion of titanium alloy shell, titanium alloy shell head be end of probe and its be provided with sensor site and be provided with skylight, skylight and conducting wire incoming end are sealed with biocompatible glue It is stifled；The configuration of the present invention is simple, probe encapsulation is simple, and volume is suitable.
Description
Technical field
The present invention relates to organism physiological parameter measuring device device technical fields, and in particular to a kind of implanted micro sensor
Bougie structure and its packaging method.
Background technique
Physiological parameter (such as intracranial pressure, encephalic temperature, partial pressure of oxygen, intravascular pressure) monitoring is cured in clinic in organisms
Significant in and zoology, the measurement of these physiological parameters is often required by advanced sensor technology, and
It is required that a bougie can simultaneously measure a variety of body physiological parameters, and transfer data in corresponding patient monitor.
Multi-parameter bougie needs integrated multiple sensors to guarantee measurement demand, while being also required to guarantee to enter organism
Safety.In addition, popping one's head in typically small to reach minimally invasive purpose, but internal sensor composition is complex, causes to encapsulate
Difficulty is high, so that the encapsulation difficulty of present probe is big.So being badly in need of researcher studies a kind of simple encapsulation probe,
Keep its encapsulation simple, it is high-quality.
Summary of the invention
The invention discloses a kind of bougie structure of implanted micro sensor and its packaging methods, solve due to joining more
The probe size of number bougies is smaller, internal complicated composition, leads to the technical problem that encapsulation difficulty is high.
A kind of bougie structure of implanted micro sensor, including titanium alloy shell, pressure sensor, temperature sensor,
Circuit board and the conducting wire being connect with external plug, the circuit board use flexible circuit board, the circuit board as sensor with lead
The welding substrate of line, the pressure sensor and temperature sensor are located on circuit board, and the pressure sensor on circuit board is placed
Area, pressure sensor pad, temperature sensor rest area, conducting wire welded disc are successively arranged in a linear, the position of the electrode of circuit board
In in pressure sensor welded disc and conducting wire welded disc, one end that the circuit board is provided with pressure sensor is located at titanium alloy tube
The head of shell, conducting wire welded disc are located at the tail portion of titanium alloy shell, and titanium alloy shell head is end of probe, titanium alloy tube
Shell is provided with sensor and the side far from circuit board is provided with skylight, and skylight and conducting wire access end part are sealed with biocompatible glue
It is stifled；
The diameter of the conducting wire is 0.5mm, and there are 6 enamel-cover cores in inside, wherein 4 cores are made into winding displacement, winding displacement
It is connected at the wire pad of circuit board.
Further, the size of the circuit board is 3.5mm*0.5mm*0.07mm.
A kind of bougie packaging method of implanted micro sensor, sequentially includes the following steps:
Step 1: production conducting wire, includes 6 cores in conducting wire, wherein 4 cores are made into winding displacement, 6 cores integrally twists with
Afterwards, the conducting wire of 0.5mm is made of coextrusion processes；
Step 2: exposing the enameled wire of 6 cores of different colours after the surrounding layer of conducting wire is taken off；
Step 3: the winding displacement is welded on circuit board by the way of nano-weld platform manual welding or press welder pressure welding
On conducting wire welded disc on；
Step 4: pressure sensor is placed on the corresponding pressure sensor rest area of circuit board using vacuum WAND,
And it is adhesively fixed with bonding die glue.
Step 5: then being used on two-sided 2 in addition to the winding displacement piece core for being welded to the conducting wire of temperature sensor
Bonding die glue is fixed on the temperature sensor rest area corresponding position on circuit board；
Step 6: the electrode one in the pressure sensor welded disc on the electrode and circuit board on pressure sensor is a pair of
It should weld；
Step 7: fixed in titanium alloy shell by being sent into after the circuit board bottom gluing after welding；
Step 8: being fixed in conducting wire and titanium alloy shell contact position using uv-curable glue；
Step 9: skylight and conducting wire incoming end the coating biocompatible glue of titanium alloy shell are blocked.
Further, 6 core wires use whole and Kafra fiber twisting, and sulphur is added in the outsourcing layer of conducting wire
Sour barium.
Beneficial effects of the present invention: wherein 4 cores are made into winding displacement to the core of conducting wire in the present invention, and 4 cores for being made into winding displacement are used for
On circuit boards, when connection, the core occupied space for being made into winding displacement is smaller for connection, flexible circuit board Distribution density is high, it is light-weight,
Thickness is thin, so that the occupied space of circuit board is smaller while nor affecting on wiring, pressure sensor chip rest area, pressure sensing
Device pad, temperature sensor rest area, wire pad are arranged successively and are in line, so that and probe width occupies less, so that
Required wound is smaller when probe enters organism.The probe encapsulated using the bougie packaging method in the present invention, operation letter
Single, packaging effect is good, keeps its probe size smaller.
Detailed description of the invention
Fig. 1 is the structural diagram of the present invention.
Fig. 2 is probe internal structure connection schematic diagram.
Component label instructions: titanium alloy shell 1, pressure sensor welded disc 3, temperature sensor 4, is led at pressure sensor 2
Line 5, winding displacement 6, conducting wire welded disc 7, plug 8, skylight 9, circuit board 10.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
As shown in Figs. 1-2, a kind of bougie structure of implanted micro sensor, including titanium alloy shell 1, pressure sensor
2, temperature sensor 4, circuit board 10 and the conducting wire 5 connecting with external plug 8, the circuit board 10 use flexible circuit board, should
Welding substrate of the circuit board 10 as sensor and conducting wire 5, the pressure sensor 2 and temperature sensor 4 are located at circuit board 10
On, pressure sensor rest area, pressure sensor pad 3 on circuit board 10, temperature sensor rest area, conducting wire welded disc 7
It is successively arranged in a linear, being located in pressure sensor welded disc 3 and conducting wire welded disc 7 for the electrode of circuit board 10 makes in this way
It obtains circuit board 10 and sensor occupied space in same plane, wiring is smaller.The circuit board 10 is provided with pressure sensor 2
One end be located at the head of titanium alloy shell 1, conducting wire welded disc 7 is located at the tail portion of titanium alloy shell 1, the titanium alloy shell 1
Head is end of probe, titanium alloy shell 1 is provided with sensor site and the side far from circuit board 5 is provided with skylight 9, Kaitian
The purpose of window 9 is to guarantee that each sensor is directly contacted with ambient pressure environment, and skylight 9 and 5 incoming end of conducting wire are with biological
Compatible glue blocks, and not only can protect sensor with biocompatible glue closure at skylight 9 and is also able to satisfy and meets bio-compatible
Property requirement, and guarantee mellow and full smooth, so that probe detects smooth in vivo.
The plug 8 of one end outside the connection of conducting wire 5 probe is generally USB plug, and signal is facilitated to transmit.Flexible circuit
Plate (Flexible printed circuit Board) abbreviation soft board or FPC are the printings made of insulating substrate flexible
Circuit has the advantages that many rigid printed circuit boards 10 do not have, and has the characteristics that Distribution density is high, light-weight, thickness is thin.
5 size of conducting wire is 0.5mm, and there are 6 cores in inside, wherein 4 cores are made into winding displacement 6, winding displacement 6 is connected to electricity
At the conducting wire welded disc 7 of road plate 10.
Further, the size of the circuit board 10 is 3.5mm*0.5mm*0.07mm.The circuit board 10 of such size is big
It is small suitable, it is easy for installation.
A kind of bougie packaging method of implanted pressure and temperature sensor, sequentially includes the following steps:
It include 6 cores in conducting wire 5, wherein 4 cores are made into 6,6 core entirety of winding displacement Step 1: making conducting wire 5
It twists with after, the conducting wire 5 of 0.5mm is made of coextrusion processes；
Step 2: exposing the enameled wire of 6 cores of different colours after the surrounding layer of conducting wire 5 is taken off.
Step 3: the winding displacement 6 is welded on circuit by the way of nano-weld platform manual welding or press welder pressure welding
In conducting wire welded disc 7 on plate 10.Slurry is made into using nano-noble metal powder when nano-weld to sinter at a lower temperature
Then electrode welds, may be alternatively configured solder and prepare soldering paste, required welding condition is lower, carries out the welding of particular demands.Press welder
It is a kind of welding platform mechanical equipment, mainly uses floating installation, act directly on welding pressure on turntable, reach hot pressing
Precision welding is realized in the accurate positioning of welding.
It is placed Step 4: pressure sensor 2 is placed on the corresponding pressure sensor of flexible circuit board using vacuum WAND
Qu Shang, and be adhesively fixed with bonding die glue.Vacuum WAND is a kind of miniature pneumatic tool of outer image pen.It by plastics or
Person's rubber shell, vacuum generator (air-driven type), vacuum chuck, elbow and pipe crimping (air-driven type) composition, can be flexibly applied to
The assembly of small part.
Step 5: then being adopted on two-sided 2 cores for being welded to the conducting wire 5 in addition to winding displacement 6 of temperature sensor 4
It is fixed on the temperature sensor rest area corresponding position on circuit board 10 with bonding die glue, so that temperature sensor 4 and 5 points of conducting wire
Connection.
Step 6: one by one by the electrode on the pressure sensor pad 7 on the electrode and circuit board 10 on pressure sensor 2
Corresponding welding；
Step 7: it is fixed in titanium alloy shell 1 by being sent into after the 10 bottom gluing of circuit board after welding, enhancing conducting wire 5
Tear-strength.
Step 8: being fixed in conducting wire 5 and 1 contact position of titanium alloy shell using uv-curable glue.
Step 9: 1 skylight 9 of titanium alloy shell and 5 incoming end of conducting wire coating biocompatible glue are blocked.
Further, 6 core wires use whole and Kafra fiber twisting, are added in the outsourcing layer of conducting wire 5
Barium sulfate.Meet radiopacity requirement.Probe is measured into animal body, needs to meet medical high polymer standard of articles,
In this standard wherein one be exactly radiopacity requirement.
In the description of the present invention, it is to be understood that, term " coaxial ", " bottom ", " one end ", " top ", " middle part ",
The orientation or position of the instructions such as " other end ", "upper", " side ", " top ", "inner", "outside", " front ", " center ", " both ends "
Relationship is to be based on the orientation or positional relationship shown in the drawings, and is merely for convenience of description of the present invention and simplification of the description, without referring to
Show or imply that signified device or element must have a particular orientation, be constructed and operated in a specific orientation, therefore cannot manage
Solution is limitation of the present invention.
In the present invention unless specifically defined or limited otherwise, term " installation ", " setting ", " connection ", " fixation ",
Terms such as " rotations " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or integral；It can be with
It is mechanical connection, is also possible to be electrically connected；It can be directly connected, two can also be can be indirectly connected through an intermediary
The interaction relationship of connection or two elements inside a element, unless otherwise restricted clearly, for the common of this field
For technical staff, the specific meanings of the above terms in the present invention can be understood according to specific conditions.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding
And modification, the scope of the present invention is defined by the appended.
Claims (4)
1. a kind of bougie structure of implanted micro sensor, including titanium alloy shell (1), pressure sensor (2), temperature sensing
Device (4), circuit board (10) and the conducting wire (5) being connect with external plug (8), which is characterized in that the circuit board (10) is using soft
Property circuit board, the welding substrate of the circuit board (10) as sensor and conducting wire (5), the pressure sensor (2) and temperature pass
Sensor (4) is located on circuit board (10), pressure sensor rest area, pressure sensor pad (3), temperature on circuit board (10)
Sensor rest area, conducting wire welded disc (7) are successively arranged in a linear, and the electrode of circuit board (10) is located at pressure sensor welded disc
(3) and in conducting wire welded disc (7), one end that circuit board (10) is provided with pressure sensor (2) is located at the head of titanium alloy shell (1)
Portion, conducting wire welded disc (7) are located at the tail portion of titanium alloy shell (1), and titanium alloy shell (1) head is end of probe, and titanium closes
Golden shell (1) is provided with sensor and the side far from circuit board (5) is provided with skylight (9), skylight (9) and conducting wire (5) incoming end
Part is blocked with biocompatible glue；
The diameter of the conducting wire (5) is 0.5mm, and there are 6 enamel-cover cores in inside, wherein 4 cores are made into winding displacement (6), row
Line (6) is connected at the wire pad (7) of circuit board (10).
2. a kind of bougie structure of implanted micro sensor according to claim 1, which is characterized in that the circuit board
(10) size is 3.5mm*0.5mm*0.07mm.
3. a kind of bougie packaging method of implanted micro sensor, which is characterized in that sequentially include the following steps:
It include 6 cores in conducting wire (5), wherein 4 cores are made into winding displacement (6), 6 cores are whole Step 1: making conducting wire (5)
Body is twisted with after, and the conducting wire (5) of 0.5mm is made of coextrusion processes；
Step 2: exposing the enameled wire of 6 cores of different colours after the surrounding layer of conducting wire (5) is taken off；
Step 3: the winding displacement (6) is welded on circuit board by the way of nano-weld platform manual welding or press welder pressure welding
(10) in the conducting wire welded disc (7) on；
Step 4: pressure sensor (2) is placed on the corresponding pressure sensor rest area of circuit board (10) using vacuum WAND
On, and be adhesively fixed with bonding die glue；
It is welded on 2 cores in addition to winding displacement (6) of the conducting wire (5) Step 5: temperature sensor (4) is two-sided, so
It is fixed on the temperature sensor rest area corresponding position on circuit board (10) using bonding die glue afterwards；
Step 6: by the electrode on the electrode on pressure sensor (2) and the pressure sensor welded disc (3) on circuit board (10)
Correspond welding；
Step 7: fixed in titanium alloy shell (1) by being sent into after circuit board (10) bottom gluing after welding；
Step 8: being fixed in conducting wire (5) and titanium alloy shell (1) contact position using uv-curable glue；
Step 9: skylight (9) and conducting wire (5) incoming end the coating biocompatible glue of titanium alloy shell (1) are blocked.
4. a kind of bougie packaging method of implanted micro sensor according to claim 3, which is characterized in that described 6
Core wire uses whole and Kafra fiber twisting, and barium sulfate is added in the outsourcing layer of conducting wire (5).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910120249.9A CN109674460A (en) | 2019-02-18 | 2019-02-18 | A kind of the bougie structure and its packaging method of implanted micro sensor |
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| CN201910120249.9A CN109674460A (en) | 2019-02-18 | 2019-02-18 | A kind of the bougie structure and its packaging method of implanted micro sensor |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110279409A (en) * | 2019-07-29 | 2019-09-27 | 成都拓蓝精创医学技术有限公司 | A kind of probe encapsulating structure of human pressure's measurement sensor |
| CN110420055A (en) * | 2019-08-22 | 2019-11-08 | 浙江舒友仪器设备有限公司 | A kind of operation electrotome pen |
| CN115944286A (en) * | 2023-03-09 | 2023-04-11 | 深圳湃诺瓦医疗科技有限公司 | Artificial intelligence assisted intracranial monitoring system and bougie assembly |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110279409A (en) * | 2019-07-29 | 2019-09-27 | 成都拓蓝精创医学技术有限公司 | A kind of probe encapsulating structure of human pressure's measurement sensor |
| CN110420055A (en) * | 2019-08-22 | 2019-11-08 | 浙江舒友仪器设备有限公司 | A kind of operation electrotome pen |
| CN115944286A (en) * | 2023-03-09 | 2023-04-11 | 深圳湃诺瓦医疗科技有限公司 | Artificial intelligence assisted intracranial monitoring system and bougie assembly |
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Application publication date: 20190426 |
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