CN109673981A - A kind of HuGan oral liquid and preparation method thereof - Google Patents
A kind of HuGan oral liquid and preparation method thereof Download PDFInfo
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- 239000007788 liquid Substances 0.000 title claims abstract description 39
- 238000002360 preparation method Methods 0.000 title claims abstract description 7
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims abstract description 33
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims abstract description 33
- 241000209140 Triticum Species 0.000 claims abstract description 22
- 235000021307 Triticum Nutrition 0.000 claims abstract description 22
- 235000016709 nutrition Nutrition 0.000 claims abstract description 14
- 230000035764 nutrition Effects 0.000 claims abstract description 14
- 108010068370 Glutens Proteins 0.000 claims abstract description 12
- 238000000855 fermentation Methods 0.000 claims abstract description 12
- 230000004151 fermentation Effects 0.000 claims abstract description 12
- 235000021312 gluten Nutrition 0.000 claims abstract description 12
- BVTBRVFYZUCAKH-UHFFFAOYSA-L disodium selenite Chemical compound [Na+].[Na+].[O-][Se]([O-])=O BVTBRVFYZUCAKH-UHFFFAOYSA-L 0.000 claims abstract description 11
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims abstract description 11
- 235000015921 sodium selenite Nutrition 0.000 claims abstract description 11
- 241000222640 Polyporus Species 0.000 claims abstract description 10
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims abstract description 8
- 235000019674 grape juice Nutrition 0.000 claims abstract description 8
- 239000002002 slurry Substances 0.000 claims abstract description 8
- 229960001471 sodium selenite Drugs 0.000 claims abstract description 8
- 239000011781 sodium selenite Substances 0.000 claims abstract description 8
- 230000001954 sterilising effect Effects 0.000 claims abstract description 8
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 claims abstract description 6
- 241000222684 Grifola Species 0.000 claims abstract description 6
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 claims abstract description 6
- 239000000843 powder Substances 0.000 claims abstract description 6
- 238000000034 method Methods 0.000 claims abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 5
- 239000000084 colloidal system Substances 0.000 claims abstract description 4
- 238000011049 filling Methods 0.000 claims abstract description 4
- 229910052943 magnesium sulfate Inorganic materials 0.000 claims abstract description 4
- 235000019341 magnesium sulphate Nutrition 0.000 claims abstract description 4
- 229910000402 monopotassium phosphate Inorganic materials 0.000 claims abstract description 4
- 235000019796 monopotassium phosphate Nutrition 0.000 claims abstract description 4
- PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 claims abstract description 4
- 238000007789 sealing Methods 0.000 claims abstract description 4
- 241000219095 Vitis Species 0.000 claims description 9
- 235000009754 Vitis X bourquina Nutrition 0.000 claims description 9
- 235000012333 Vitis X labruscana Nutrition 0.000 claims description 9
- 235000014787 Vitis vinifera Nutrition 0.000 claims description 9
- 238000003756 stirring Methods 0.000 claims description 9
- 239000001963 growth medium Substances 0.000 claims description 7
- 101000693530 Staphylococcus aureus Staphylokinase Proteins 0.000 claims description 3
- 238000000605 extraction Methods 0.000 claims description 3
- 235000013305 food Nutrition 0.000 claims description 3
- 241000385540 bacterium 10 Species 0.000 claims description 2
- 238000005238 degreasing Methods 0.000 claims 1
- 210000004185 liver Anatomy 0.000 abstract description 16
- 229940100688 oral solution Drugs 0.000 abstract description 6
- 230000035622 drinking Effects 0.000 abstract description 3
- 235000009508 confectionery Nutrition 0.000 abstract description 2
- 235000013399 edible fruits Nutrition 0.000 abstract description 2
- 235000013402 health food Nutrition 0.000 abstract description 2
- 238000001816 cooling Methods 0.000 abstract 2
- 108090000145 Bacillolysin Proteins 0.000 abstract 1
- 102000035092 Neutral proteases Human genes 0.000 abstract 1
- 108091005507 Neutral proteases Proteins 0.000 abstract 1
- 239000011669 selenium Substances 0.000 description 17
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 16
- 229910052711 selenium Inorganic materials 0.000 description 16
- 229940091258 selenium supplement Drugs 0.000 description 16
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 description 10
- 230000000694 effects Effects 0.000 description 7
- 230000003908 liver function Effects 0.000 description 6
- 108010024636 Glutathione Proteins 0.000 description 5
- 229960003180 glutathione Drugs 0.000 description 5
- 239000002994 raw material Substances 0.000 description 4
- 235000008429 bread Nutrition 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 210000001161 mammalian embryo Anatomy 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 208000019901 Anxiety disease Diseases 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 208000004930 Fatty Liver Diseases 0.000 description 1
- 229940123457 Free radical scavenger Drugs 0.000 description 1
- 206010019708 Hepatic steatosis Diseases 0.000 description 1
- 206010067125 Liver injury Diseases 0.000 description 1
- 241000196323 Marchantiophyta Species 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 230000036506 anxiety Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 102000006995 beta-Glucosidase Human genes 0.000 description 1
- 108010047754 beta-Glucosidase Proteins 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 208000019425 cirrhosis of liver Diseases 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 210000002257 embryonic structure Anatomy 0.000 description 1
- 208000010706 fatty liver disease Diseases 0.000 description 1
- 235000013312 flour Nutrition 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 231100000234 hepatic damage Toxicity 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000000622 irritating effect Effects 0.000 description 1
- 210000005229 liver cell Anatomy 0.000 description 1
- 230000008818 liver damage Effects 0.000 description 1
- 208000019423 liver disease Diseases 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 238000009629 microbiological culture Methods 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 150000008442 polyphenolic compounds Chemical class 0.000 description 1
- 235000013824 polyphenols Nutrition 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 239000002516 radical scavenger Substances 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 230000000391 smoking effect Effects 0.000 description 1
- 231100000240 steatosis hepatitis Toxicity 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/09—Mashed or comminuted products, e.g. pulp, purée, sauce, or products made therefrom, e.g. snacks
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof
- A23L7/10—Cereal-derived products
- A23L7/104—Fermentation of farinaceous cereal or cereal material; Addition of enzymes or microorganisms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Inorganic Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of HuGan oral liquids and preparation method thereof, belong to health food processing technique field.Water is added to mix thoroughly in defatted wheat germ powder, neutral protease enzymolysis is added and obtains wheat gluten hydrolyzate, maltose and food-grade sodium selenite are added in wheat gluten hydrolyzate, it is sterilized, it is cooling, Saccharomyces cerevisiae ferments to obtain Saccharomyces cerevisiae fermentation liquid, Saccharomyces cerevisiae fermentation liquid is sterilized to obtain yeast nutrition liquid, yeast nutrition liquid and grape juice are uniformly mixed to obtain mixed juice, potassium dihydrogen phosphate and magnesium sulfate are added in mixed juice, it is sterilized, cooling is followed by obtaining polyporus frondosus fermenting liquor into grifola frondosus strain fermentation, polyporus frondosus fermenting liquor obtains nutrition slurries through mycelium colloid mill defibrination, nutrition slurries are using filter, allotment, it is filling, sealing, sterilizing is got product.Oral solution of the invention not only safe for drinking, in good taste, the smell of fruits is very sweet, but also have the function of liver protecting.
Description
Technical field
The invention discloses a kind of HuGan oral liquids and preparation method thereof, belong to health food processing technique field.
Background technique
Nourishing the liver and protect liver are all the vital tasks of our health cares, all easy pair of many kinds of situations in daily life
Liver damages, and modern society, life stress is big, and rhythm of life is also fast, stays up late for a long time, unreasonable diet work and rest, length
Phase is in the state of nervous anxiety, excessively takes in situations such as alcohol, excessively smoking, all affects the strong of liver in subtle
Health.Understand how that reinforcing liver has protected liver, the disease of body will be reduced, and therefore, modern's liver protecting is particularly important.
Summary of the invention
The object of the present invention is to provide a kind of safe for drinking, the HuGan oral liquid that in good taste, the smell of fruits is very sweet and its preparation sides
Method.
The object of the present invention is achieved like this:
The defatted wheat germ powder of certain mass is weighed, the clear water of 8-12 times of quality is added, stirs evenly, by every gram of defatted wheat
Neutral proteinase is added in the ratio of germ flour 80-100 unit, and wheat gluten water is hydrolyzed 6-8 hours to obtain under the conditions of 48-52 DEG C
Solve liquid.
60-100 grams of maltose is added according to every liter of wheat gluten hydrolyzate in the wheat gluten hydrolyzate for measuring certain volume
Ratio maltose is added, food is added in the ratio that 30 milligrams of food-grade sodium selenites are added according still further to every liter of wheat gluten hydrolyzate
Grade sodium selenite, stirs evenly, and cools to 28-32 DEG C after sterilizing 15-20 minutes under the conditions of 121 DEG C, obtains yeast culture medium,
0.1% baker's active dried yeast, shaking table culture under conditions of 28-32 DEG C, 160-200rpm are added in yeast culture medium
Obtain Saccharomyces cerevisiae fermentation liquid within 20-24 hours, Saccharomyces cerevisiae fermentation liquid is sterilized under the conditions of 121 DEG C 10-15 minutes to obtain yeast battalion
Nutrient solution.
Grape extraction juice is obtained into grape juice, is uniformly mixed yeast nutrition liquid and grape juice according to the ratio of mass ratio 8:1
Mixed juice.
0.1% potassium dihydrogen phosphate, 0.05% magnesium sulfate are added in mixed juice, stirs evenly, under the conditions of 90-95 DEG C
Sterilizing 10 minutes, cools to 24-26 DEG C, grifola frondosus strain is accessed from inclined-plane, under conditions of 24-26 DEG C, 160-200rpm
Obtain polyporus frondosus fermenting liquor within shaking table culture 145-155 hours, polyporus frondosus fermenting liquor obtains nutrition slurries through mycelium colloid mill defibrination, seeks
Slurries are supported to get product using filter, allotment, filling, sealing, sterilizing.
HuGan oral liquid beneficial effect of the invention includes the following aspects:
First, raw materials used HuGan oral liquid of the invention is all natural food materials, is free from side effects to human body, and edible is safety
's.
Second, HuGan oral liquid of the invention is deployed based on polyporus frondosus fermenting liquor, polyporus frondosus fermenting liquor
In contain grifolan abundant, grifolan can be substantially reduced the content of cholesterol in serum and triglycerides, have
Treat fatty liver and liver protection, the effect of protect liver.
Third, the raw material of HuGan oral liquid of the invention contain grape, and modern medicine proves, Polyphenols contained in grape
Substance is natural free radical scavenger, has very strong antioxidant activity, can effectively adjust the function of liver cell, support
Injuries imperial or that reduction free radical is to them.
4th, HuGan oral liquid of the invention contains selenium element abundant, and selenium energy strengthen immunity reduces hepatopathy repeatedly,
Oxidation resistance can also be improved, prevents liver fibrosis, in addition there are also detoxications for selenium, can protect liver.The present invention is in bread
It is added to food-grade sodium selenite during yeast-leavened, selenium contained by food-grade sodium selenite is inorganic selenium, and inorganic selenium is not
It is only not easy to be absorbed by the body, and inorganic selenium, to the irritating effect of stomach and intestine, Saccharomyces cerevisiae has stronger accumulation ability to inorganic selenium,
Inorganic selenium can be converted into Biological Selenium in conjunction with the intracorporal protein of Saccharomyces cerevisiae and polysaccharide organic, to eliminate inorganic selenium pair
The stimulation of stomach enables selenium to be preferably absorbed by the body utilization.It is removed by measuring bread fermentation liquid of the present invention through centrifugation
Food-grade sodium selenite content is extremely low in clear liquid after removing yeast thallus, and food-grade sodium selenite only has 2.3 millis in every liter of clear liquid
Gram, illustrate that the food-grade sodium selenite of 90% or more in yeast culture medium is all absorbed by yeast and is converted to Biological Selenium.
5th, HuGan oral liquid of the invention has strong grape fruity, and grape juice is after frondosa fermentation, ash tree
Reference state aroma-producing substance in grape can be converted to free state aroma-producing substance by the beta-glucosidase that flower metabolism generates, and be increased
The grape fruity of HuGan oral liquid of the present invention can effectively overcome the shortcomings of that conventional oral liquid taste is bad.
6th, the raw material of HuGan oral liquid of the invention includes wheat embryo, but also Saccharomyces cerevisiae rich in,
Contain glutathione abundant in Saccharomyces cerevisiae, wheat embryo, glutathione has removing toxic substances and oxidation resistance, has very strong guarantor
Protecting liver effect, many hepatics all contain glutathione ingredient.
7th, the present invention by the fermentation of Saccharomyces cerevisiae and grifola frondosus by raw materials such as grape, wheat embryos dexterously
It is combined together, by synergistic effect, the effect of having played oral solution liver protecting of the present invention to the maximum extent.
Specific embodiment
The grifola frondosus CICC50072 that the present invention uses is purchased in Chinese industrial Microbiological Culture Collection administrative center.
200 grams of defatted wheat germ powder are weighed, 2000 grams of clear water are added, stir evenly, by every gram of defatted wheat germ powder
Neutral proteinase is added in the ratio of 90 units, and wheat gluten hydrolyzate is hydrolyzed 7 hours to obtain under the conditions of 50 DEG C.
1 liter of wheat gluten hydrolyzate is taken, 80 grams of maltose, 30 milligrams of food-grade sodium selenites are added, stir evenly,
30 DEG C are cooled to after sterilizing 15 minutes under the conditions of 121 DEG C, obtains yeast culture medium, the bread that 0.1% is added in yeast culture medium is lived
Property dry ferment, under conditions of 30 DEG C, 180rpm shaking table culture 22 hours Saccharomyces cerevisiae fermentation liquid, by Saccharomyces cerevisiae fermentation liquid
Sterilize 10 minutes to obtain yeast nutrition liquid under the conditions of 121 DEG C.
Grape extraction juice is obtained into grape juice, is uniformly mixed yeast nutrition liquid and grape juice according to the ratio of mass ratio 8:1
Mixed juice.
0.1% potassium dihydrogen phosphate, 0.05% magnesium sulfate are added in mixed juice, stirs evenly, goes out under the conditions of 90 DEG C
Bacterium 10 minutes, 25 DEG C are cooled to, grifola frondosus strain is accessed from inclined-plane, shaking table culture 150 is small under conditions of 25 DEG C, 180rpm
When obtain polyporus frondosus fermenting liquor, polyporus frondosus fermenting liquor obtains nutrition slurries through mycelium colloid mill defibrination, nutrition slurries using filter, adjust
Match, is filling, sealing, sterilizing gets product.
The oral solution for taking the embodiment of the present invention measures the content of its GSH-PX activity and selenium, the results are shown in Table 1:
Table 1: oral solution GSH-PX activity and Se content table of the present invention
| Project | As a result |
| Glutathione (mg/litre) | 165.4 |
| Selenium (mg/litre) | 16.9 |
As it can be seen from table 1 the oral solution of the embodiment of the present invention contains glutathione abundant and selenium, both ingredients all have very
Strong liver protection function.
HuGan oral liquid efficacy test of the present invention:
Test method: 50 people of subject of abnormal liver function when screening physical examination allows this 50 subjects to drink the embodiment of the present invention
HuGan oral liquid, test period are 90 days, 150 milliliters of HuGan oral liquid for drinking the embodiment of the present invention during test daily, 90
After it, liver function is checked, and be compared with the oral preceding physical examination situation of protect liver of the present invention is drunk.
Test result criterion:
1 is effective: liver power recovery is normal；
2 effectively: liver function indexes are improved；
3 is invalid: liver function indexes are unchanged or aggravate.
Test result is shown in Table 2:
Table 2: subject's liver function indexes improve situation table
| Tested number | Effective number | Efficiently individual quantity | Invalid number | Total effective rate |
| 50 | 9 | 32 | 9 | 82% |
As can be seen from the above table, after the HuGan oral liquid for taking the embodiment of the present invention, the liver function indexes of most subjects are changed
Kind, total effective rate illustrates that oral solution of the invention has effects that liver protection up to 82%.
Claims (2)
1. a kind of preparation method of HuGan oral liquid, it is characterized in that being prepared by following process:
(1) the defatted wheat germ powder of certain mass is weighed, the clear water of 8-12 times of quality is added, stirs evenly, it is small by every gram of degreasing
Neutral proteinase is added in the ratio of wheat germ powder 80-100 unit, and wheat gluten is hydrolyzed 6-8 hours to obtain under the conditions of 48-52 DEG C
Hydrolyzate；
(2) 60-100 grams of maltose is added according to every liter of wheat gluten hydrolyzate in the wheat gluten hydrolyzate for measuring certain volume
Maltose is added in ratio, and food is added in the ratio that 30 milligrams of food-grade sodium selenites are added according still further to every liter of wheat gluten hydrolyzate
Grade sodium selenite, stirs evenly, cools to 28-32 DEG C after sterilizing 15-20 minutes under the conditions of 121 DEG C, obtain yeast culture medium,
0.1% baker's active dried yeast, shaking table culture 20- under conditions of 28-32 DEG C, 160-200rpm are added in yeast culture medium
Obtain Saccharomyces cerevisiae fermentation liquid within 24 hours, Saccharomyces cerevisiae fermentation liquid is sterilized under the conditions of 121 DEG C 10-15 minutes to obtain yeast nutrition
Liquid；
(3) grape extraction juice is obtained into grape juice, according to the ratio of mass ratio 8:1 yeast nutrition liquid and grape juice are uniformly mixed mixed
Close juice；
(4) 0.1% potassium dihydrogen phosphate, 0.05% magnesium sulfate are added in mixed juice, stirs evenly, goes out under the conditions of 90-95 DEG C
Bacterium 10 minutes, 24-26 DEG C is cooled to, grifola frondosus strain is accessed from inclined-plane, is shaken under conditions of 24-26 DEG C, 160-200rpm
Bed culture obtains polyporus frondosus fermenting liquor in 145-155 hours, and polyporus frondosus fermenting liquor obtains nutrition slurries, nutrition through mycelium colloid mill defibrination
Slurries are got product using filter, allotment, filling, sealing, sterilizing.
2. HuGan oral liquid made from preparation method according to claim 1.
Priority Applications (1)
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| CN201811460306.XA CN109673981A (en) | 2018-12-01 | 2018-12-01 | A kind of HuGan oral liquid and preparation method thereof |
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| CN201811460306.XA CN109673981A (en) | 2018-12-01 | 2018-12-01 | A kind of HuGan oral liquid and preparation method thereof |
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| CN109673981A true CN109673981A (en) | 2019-04-26 |
Family
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| CN101194917A (en) * | 2007-11-21 | 2008-06-11 | 贵州大学 | Grifola frondosa oral liquid rich in gastrodine, organic selenium and method for preparing the same |
| CN102972213A (en) * | 2012-12-31 | 2013-03-20 | 黄河三角洲京博化工研究院有限公司 | Grifola frondosa strain and method utilizing strain for liquid fermentation to cogenerate laccase and beta-glucan |
| CN104996715A (en) * | 2015-07-08 | 2015-10-28 | 青岛嘉瑞生物技术有限公司 | A processing method for preparing wheat germ polypeptide by a compound fermentation method |
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2018
- 2018-12-01 CN CN201811460306.XA patent/CN109673981A/en not_active Withdrawn
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