CN109668884A - A kind of chemical indicator and monitoring method monitoring oxidized form disinfectant Disinfection Effect - Google Patents
A kind of chemical indicator and monitoring method monitoring oxidized form disinfectant Disinfection Effect Download PDFInfo
- Publication number
- CN109668884A CN109668884A CN201910126952.0A CN201910126952A CN109668884A CN 109668884 A CN109668884 A CN 109668884A CN 201910126952 A CN201910126952 A CN 201910126952A CN 109668884 A CN109668884 A CN 109668884A
- Authority
- CN
- China
- Prior art keywords
- chemical indicator
- oxidized form
- disinfection effect
- monitoring
- exposed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N2021/775—Indicator and selective membrane
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plasma & Fusion (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Abstract
The invention discloses a kind of chemical indicators for monitoring oxidized form disinfectant Disinfection Effect, including indication compound and printing ink composition, the indication compound is triarylmethane dye, the indication compound and printing ink composition mass percent are as follows: 6~10%:90~94%, the triarylmethane dye, which is exposed to color in oxidized form disinfectant disinfecting process, can occur significant change.A method of monitoring oxidized form disinfectant disinfecting process, method includes the following steps: chemical indicator is placed under identical conditions for sterilization together with by sterilizing objects;The color change for observing chemical indicator judges Disinfection Effect, when chemical indicator is exposed in wet oxidized form disinfectant, especially in ozone when, show apparent color change;When chemical indicator is exposed in dry oxidized form disinfectant or oxygen, color change does not occur.Chemical indicator monitoring disinfection result of the present invention is quickly and color instruction variation is obvious, has preferable indicative function.
Description
Technical field
The invention belongs to chemical indicator technical field more particularly to a kind of changes for monitoring oxidized form disinfectant Disinfection Effect
Learn indicator and monitoring method.
Background technique
Disinfection is all in need in many fields, especially medical domain.Ozone is a kind of oxidized form disinfectant, disinfection effect
Fruit will receive the influence of the factors such as humidity, temperature.Ozone can carry out sterilizing in low temperature or at room temperature, and ozone is in height
Temperature is lower to be easy to decompose, so ozone is not need high temperature in disinfection, this is an advantage of ozonization.Certainly, it monitors smelly
It is also highly important that whether the disinfecting process of oxygen, which reaches Disinfection Effect,.
Chemical indicator design principle is to occur to have characteristic according to one or more physical conditions in sterilizing cabin
Color change.Chemical indicator is usually used in combination with other sterilization monitor devices, is exposed in sterilizing cabin.According to routine,
Biological indicator is placed in sterilizing cabin to monitor Disinfection Effect, biological indicator is made of the bacterium item containing a large amount of microorganisms
, after sanitized, bacterium item is cultivated, observes microorganism growing state, judges whether disinfection succeeds.If using this
Mode monitors Disinfection Effect, and disinfection result need to wait at least for 24 hours, is unfavorable for the development of follow-up work in this way.Therefore, it is necessary to
There is a kind of method quickly to monitor disinfection situation.
The object of the present invention is to provide a kind of in the disinfecting process of oxidized form disinfectant, especially in ozone disinfection process
The indicator and method of Disinfection Effect are monitored, and can quickly monitor disinfection situation.
Summary of the invention
It is an object of the invention to: Disinfection Effect is monitored using traditional bionidicator for above-mentioned, sterilizes result
The problem of need to waiting at least for 24 hours, being unfavorable for the development of follow-up work, the present invention provide a kind of monitoring oxidized form disinfectant and disappear
The chemical indicator and monitoring method of toxic effect fruit.
The technical solution adopted by the invention is as follows:
A kind of chemical indicator monitoring oxidized form disinfectant Disinfection Effect, including indication compound and printing ink composition,
The indication compound be triarylmethane dye, the printing ink composition include: solvent, pH adjusting agent, viscosity modifier,
Defoaming agent, oil base, evaporation or drying aids, the indication compound and printing ink composition mass percent are as follows: 6~10%:90
~94%, the triarylmethane dye structural formula are as follows:
Ar is substituted or unsubstituted aryl, and Ar' is cyclohexadienyl substituted or unsubstituted, and wherein Ar is phenyl or substitution
Phenyl, the substituent group on Ar include hydroxyl, halogen (such as bromine or chlorine), lower alkyl (such as methyl, ethyl or isopropyl), sulfonate and
Carboxyl, the triarylmethane dye, which is exposed to color in oxidized form disinfectant disinfecting process, can occur significant change.
As a preferred mode, the substituent group in the triarylmethane dye structure on Ar at least contains one
Hydroxyl.
As a preferred mode, the indication compound is rhodizonic acid.This indication compound is not only in ozone
It can change colour in disinfecting process, and dual visible change can be showed in the disinfecting process of two half periods.At the beginning of the compound
Beginning state is red, becomes crocus or light orange, after second half of the cycle terminates or sterilizes, face after preceding half period
Color obviously bleaches color or colourless.
As a preferred mode, the indication compound has photostability.Indication compound is especially to fluorescence
Lamp and sunlight have photostability, and such chemical indicator will not be by shadow long-time is exposed to color change under light
It rings.
As a preferred mode, the oil base is non-foamed nonionic mineral oil, and pH adjusting agent is alkaline conditioner,
Adhesive is water soluble acrylic resin, and viscosity modifier is hydroxyethyl cellulose, and defrother is non-ionic mineral oil, evaporation
Agent or drying aids are compound with this function, and solvent is water or alcohol.
As a preferred mode, the pH adjusting agent is sodium hydroxide or ammonia, evaporant or drying aids be ammonia or
Alcohol.
As a preferred mode, the printing ink composition has the component of following mass percent: hydroxy ethyl fiber
Element 2.65~3.45%, sodium hydroxide 1~2.6%, acrylic resin 0.5~2.5%, ammonia 0.25~0.85%, non-foamed is non-
Ion mineral oil 0.1~0.3%, water 80.3~89.5%.
A method of monitoring oxidized form disinfectant disinfecting process, method includes the following steps:
A) chemical indicator is placed under identical conditions for sterilization together with by sterilizing objects;
B) color change of chemical indicator is observed to judge Disinfection Effect, when chemical indicator is exposed to wet oxidation
When in type disinfectant, especially in ozone when, show apparent color change;When chemical indicator is exposed to dry oxidation
When in type disinfectant or oxygen, color change does not occur.
Chemical indicator of the present invention is the composition of indication compound and ink, and this composition can be used for being coated or impregnated with
Substrate, paper are suitable substrates, and the form of narrow volume can be used by being coated or impregnated with paper, easily to tear from volume, with
Just it is used in disinfection.Coated paper or impregnated paper can be protected with transparent membrane, or paper slip can be inserted into bag, such as high
Density polyethylene synthesizes in paper bag, is exposed to indicator in disinfectant, while allowing to observe any color by transparent membrane
Variation.
There is one section of indication compound on the chemical indicator, indication compound can be combined with different devices, be formed different
Compound indicant, such as independent chemical indicator, the independent biochemical indicant comprising indication compound, challenge packet, test
Packet, adhesive tape or paster etc..
The chemical indicator forms indicator and indication compound is placed on substrate to form bar.Instruction
Band is usually by having the small pieces of material of instruction compound cross-section to form.Indicator is placed in disinfection room, is exposed to oxidized form disinfectant
In.After being exposed to the disinfectant regular hour, the indicating section of the chemical indicator has color change.
In conclusion by adopting the above-described technical solution, the beneficial effects of the present invention are:
1. the present invention judges the packaged form that chemical indicator can be made into diversified forms by the disinfection of sterilizing objects
Effect, monitoring result is quickly and color instruction variation is obvious, has preferable indicative function, simple judgment Disinfection Effect, operation
Method is simple, saves detection time and cost, high sensitivity, meets to supervising in oxidized form disinfectant especially ozone disinfection process
Survey the demand of Disinfection Effect.
Specific embodiment
All features disclosed in this specification or disclosed all methods or in the process the step of, in addition to mutually exclusive
Feature and/or step other than, can combine in any way.
Embodiment 1
A kind of chemical indicator monitoring oxidized form disinfectant Disinfection Effect, including indication compound and printing ink composition,
The indication compound be triarylmethane dye, the printing ink composition include: solvent, pH adjusting agent, viscosity modifier,
Defoaming agent, oil base, evaporation or drying aids, the indication compound and printing ink composition mass percent are as follows: 6~10%:90
~94%, the triarylmethane dye structural formula are as follows:
Ar is substituted or unsubstituted aryl, and Ar' is cyclohexadienyl substituted or unsubstituted, and wherein Ar is phenyl or substitution
Phenyl, the substituent group on Ar include hydroxyl, halogen (such as bromine or chlorine), lower alkyl (such as methyl, ethyl or isopropyl), sulfonate and
Carboxyl, the triarylmethane dye, which is exposed to color in oxidized form disinfectant disinfecting process, can occur significant change.
As a preferred mode, the substituent group in the triarylmethane dye structure on Ar at least contains one
Hydroxyl.
As a preferred mode, the indication compound is rhodizonic acid.This indication compound is not only in ozone
It can change colour in disinfecting process, and dual visible change can be showed in the disinfecting process of two half periods.At the beginning of the compound
Beginning state is red, becomes crocus or light orange, after second half of the cycle terminates or sterilizes, face after preceding half period
Color obviously bleaches color or colourless.
As a preferred mode, the indication compound has photostability.Indication compound is especially to fluorescence
Lamp and sunlight have photostability, and such chemical indicator will not be by shadow long-time is exposed to color change under light
It rings.
As a preferred mode, the oil base is non-foamed nonionic mineral oil, and pH adjusting agent is alkaline conditioner,
Adhesive is water soluble acrylic resin, and viscosity modifier is hydroxyethyl cellulose, and defrother is non-ionic mineral oil, evaporation
Agent or drying aids are compound with this function, and solvent is water or alcohol.
As a preferred mode, the pH adjusting agent is sodium hydroxide or ammonia, evaporant or drying aids be ammonia or
Alcohol.
As a preferred mode, the printing ink composition has the component of following mass percent: hydroxy ethyl fiber
Element 2.65~3.45%, sodium hydroxide 1~2.6%, acrylic resin 0.5~2.5%, ammonia 0.25~0.85%, non-foamed is non-
Ion mineral oil 0.1~0.3%, water 80.3~89.5%.
A method of monitoring oxidized form disinfectant disinfecting process, method includes the following steps:
A) chemical indicator is placed under identical conditions for sterilization together with by sterilizing objects;
B) color change of chemical indicator is observed to judge Disinfection Effect, when chemical indicator is exposed to wet oxidation
When in type disinfectant, especially in ozone when, show apparent color change;When chemical indicator is exposed to dry oxidation
When in type disinfectant or oxygen, color change does not occur.
Chemical indicator of the present invention is the composition of indication compound and ink, and this composition can be used for being coated or impregnated with
Substrate, paper are suitable substrates, and the form of narrow volume can be used by being coated or impregnated with paper, easily to tear from volume, with
Just it is used in disinfection.Coated paper or impregnated paper can be protected with transparent membrane, or paper slip can be inserted into bag, such as high
Density polyethylene synthesizes in paper bag, is exposed to indicator in disinfectant, while allowing to observe any color by transparent membrane
Variation.
There is one section of indication compound on the chemical indicator, indication compound can be combined with different devices, be formed different
Compound indicant, such as independent chemical indicator, the independent biochemical indicant comprising indication compound, challenge packet, test
Packet, adhesive tape or paster etc..
The chemical indicator forms indicator and indication compound is placed on substrate to form bar.Instruction
Band is usually by having the small pieces of material of instruction compound cross-section to form.Indicator is placed in disinfection room, is exposed to oxidized form disinfectant
In.After being exposed to the disinfectant regular hour, the indicating section of the chemical indicator has color change.
Applicability detection indication compound is carried out to a large amount of indication compound and monitors oxidized form disinfectant, especially ozone
The process of disinfection assesses chemical indicator in terms of three: color acceptability, color change, colour stable.
Color acceptability refers to the acceptability of first color state.For certain indication compounds, initial color
It is not deep or too pale enough, color acceptable assessment is carried out to triarylmethane representation compound, as a result as shown in table 1 below.
The color of 1 triarylmethane representativeness indication compound of table is acceptable
Color designation | Color | It is acceptable |
Phenol red | It is red | It is acceptable |
Rhodizonic acid | It is red | It is acceptable |
It therefore, can be using phenol red, rhodizonic acid as the candidate of indication compound according to color acceptability.
In addition, also important, the chemical indicator and oxygen do not occur when contacting color change or with disinfection
When color change it is different.Otherwise, it may not distinguish not Chu Lai disinfection when ozone validity, can to chemical indicator into
Row oxygen rinses, to exclude the interference of oxygen.
The test-strips of phenol red, rhodizonic acid indication compound are exposed in the sterilizing cabin containing wet ozone,
It is tested in dry ozone and wet oxygen, test result is as follows shown in table 2:
2 phenol red of table, rhodizonic acid indication compound are tested in the ozone and wet oxygen of the ozone, drying that moisten
As a result
Indication compound title | Before disinfection | After half period | After the completion of period | Ozone without humidity | There is the oxygen of humidity |
Rhodizonic acid (8%) | It is red | Shallow orange | It is colourless | Deep orange | It is red |
Rhodizonic acid (1%) | It is red | Crocus | It is colourless | Lightpink | Rouge and powder color |
Phenol red | Chinese red | It is colourless | It is colourless | Crocus | Crocus |
Indication compound described in table 2 and printing ink composition are coated on paper and are dried, in order to heighten the color two layers of painting, then
The paper slip of coated two layers of printing ink composition is handled as follows:
Chemical indicator test strip is exposed under autoclave and illumination respectively and is placed 21 days, as a result test is as shown in table 3:
3 phenol red of table, rhodizonic acid the chemical indicator test result under autoclave and illumination
Dye title | Autoclave | Lamp |
Rhodizonic acid (8%) | Without color change | Without color change |
Rhodizonic acid (1%) | Without color change | Without color change |
Phenol red | Without color change | It fades under light |
, can be using rhodizonic acid as indication compound according to table 2,3 result of table, but rhodizonic acid content also has one
Determine section.
Embodiment 2
A kind of chemical indicator monitoring oxidized form disinfectant Disinfection Effect, including indication compound and printing ink composition,
The indication compound is rhodizonic acid, and the printing ink composition includes: solvent, pH adjusting agent, viscosity modifier, skimming
Agent, oil base, evaporation or drying aids, the chemical indicator mass percent are as follows: rhodizonic acid 6%, hydroxyethyl cellulose
2.65%, sodium hydroxide 1%, acrylic resin 0.5%, ammonia 0.25%, non-foamed nonionic mineral oil 0.1%, water 89.5%,
The rhodizonic acid dyestuff, which is exposed to color in oxidized form disinfectant disinfecting process, can occur significant change.
As a preferred mode, the indication compound can not only change colour in ozone disinfection process, but also two
Dual visible change can be showed in the disinfecting process of a half period.The compound original state was red, by first half week
Become crocus or light orange after phase, after second half of the cycle terminates or sterilizes, color obviously bleaches color or colourless.
As a preferred mode, the indication compound has photostability.Indication compound is especially to fluorescence
Lamp and sunlight have photostability, and such chemical indicator will not be by shadow long-time is exposed to color change under light
It rings.
A method of monitoring oxidized form disinfectant disinfecting process, method includes the following steps:
A) chemical indicator is placed under identical conditions for sterilization together with by sterilizing objects;
B) color change of chemical indicator is observed to judge Disinfection Effect, when chemical indicator is exposed to wet oxidation
When in type disinfectant, especially in ozone when, show apparent color change;When chemical indicator is exposed to dry oxidation
When in type disinfectant or oxygen, color change does not occur.
Chemical indicator of the present invention is the composition of indication compound and ink, and this composition can be used for being coated or impregnated with
Substrate, paper are suitable substrates, and the form of narrow volume can be used by being coated or impregnated with paper, easily to tear from volume, with
Just it is used in disinfection.Coated paper or impregnated paper can be protected with transparent membrane, or paper slip can be inserted into bag, such as high
Density polyethylene synthesizes in paper bag, is exposed to indicator in disinfectant, while allowing to observe any color by transparent membrane
Variation.
There is one section of indication compound on the chemical indicator, indication compound can be combined with different devices, be formed different
Compound indicant, such as independent chemical indicator, the independent biochemical indicant comprising indication compound, challenge packet, test
Packet, adhesive tape or paster etc..
The chemical indicator forms indicator and indication compound is placed on substrate to form bar.Instruction
Band is usually by having the small pieces of material of instruction compound cross-section to form.Indicator is placed in disinfection room, is exposed to oxidized form disinfectant
In.After being exposed to the disinfectant regular hour, the indicating section original state of the chemical indicator is red, by first half
Become crocus or light orange after period, after second half of the cycle terminates or sterilizes, color obviously bleaches color or colourless, shows
The Disinfection Effect of oxidized form disinfectant especially ozone is preferable.
Embodiment 3
A kind of chemical indicator monitoring oxidized form disinfectant Disinfection Effect, including indication compound and printing ink composition,
The indication compound is rhodizonic acid, and the printing ink composition includes: solvent, pH adjusting agent, viscosity modifier, skimming
Agent, oil base, evaporation or drying aids, the chemical indicator mass percent are as follows: rhodizonic acid 10%, hydroxyethyl cellulose
3.45%, sodium hydroxide 2.6%, acrylic resin 2.5%, ammonia 0.85%, non-foamed nonionic mineral oil 0.3%, water
80.3%, the rhodizonic acid dyestuff, which is exposed to color in oxidized form disinfectant disinfecting process, can occur significant change.
As a preferred mode, the indication compound can not only change colour in ozone disinfection process, but also two
Dual visible change can be showed in the disinfecting process of a half period.The compound original state was red, by first half week
Become crocus or light orange after phase, after second half of the cycle terminates or sterilizes, color obviously bleaches color or colourless.
As a preferred mode, the indication compound has photostability.Indication compound is especially to fluorescence
Lamp and sunlight have photostability, and such chemical indicator will not be by shadow long-time is exposed to color change under light
It rings.
A method of monitoring oxidized form disinfectant disinfecting process, method includes the following steps:
A) chemical indicator is placed under identical conditions for sterilization together with by sterilizing objects;
B) color change of chemical indicator is observed to judge Disinfection Effect, when chemical indicator is exposed to wet oxidation
When in type disinfectant, especially in ozone when, show apparent color change;When chemical indicator is exposed to dry oxidation
When in type disinfectant or oxygen, color change does not occur.
Chemical indicator of the present invention is the composition of indication compound and ink, and this composition can be used for being coated or impregnated with
Substrate, paper are suitable substrates, and the form of narrow volume can be used by being coated or impregnated with paper, easily to tear from volume, with
Just it is used in disinfection.Coated paper or impregnated paper can be protected with transparent membrane, or paper slip can be inserted into bag, such as high
Density polyethylene synthesizes in paper bag, is exposed to indicator in disinfectant, while allowing to observe any color by transparent membrane
Variation.
There is one section of indication compound on the chemical indicator, indication compound can be combined with different devices, be formed different
Compound indicant, such as independent chemical indicator, the independent biochemical indicant comprising indication compound, challenge packet, test
Packet, adhesive tape or paster etc..
The chemical indicator forms indicator and indication compound is placed on substrate to form bar.Instruction
Band is usually by having the small pieces of material of instruction compound cross-section to form.Indicator is placed in disinfection room, is exposed to oxidized form disinfectant
In.After being exposed to the disinfectant regular hour, the indicating section original state of the chemical indicator is red, by first half
Become crocus or light orange after period, after second half of the cycle terminates or sterilizes, color obviously bleaches color or colourless, shows
The Disinfection Effect of oxidized form disinfectant especially ozone is preferable.
Embodiment 4
A kind of chemical indicator monitoring oxidized form disinfectant Disinfection Effect, including indication compound and printing ink composition,
The indication compound is rhodizonic acid, and the printing ink composition includes: solvent, pH adjusting agent, viscosity modifier, skimming
Agent, oil base, evaporation or drying aids, the chemical indicator mass percent are as follows: rhodizonic acid 8%, hydroxyethyl cellulose
3.15%, sodium hydroxide 1.8%, acrylic resin 1.5%, ammonia 0.45%, non-foamed nonionic mineral oil 0.2%, water
84.9%, the rhodizonic acid dyestuff, which is exposed to color in oxidized form disinfectant disinfecting process, can occur significant change.
As a preferred mode, the indication compound can not only change colour in ozone disinfection process, but also two
Dual visible change can be showed in the disinfecting process of a half period.The compound original state was red, by first half week
Become crocus or light orange after phase, after second half of the cycle terminates or sterilizes, color obviously bleaches color or colourless.
As a preferred mode, the indication compound has photostability.Indication compound is especially to fluorescence
Lamp and sunlight have photostability, and such chemical indicator will not be by shadow long-time is exposed to color change under light
It rings.
A method of monitoring oxidized form disinfectant disinfecting process, method includes the following steps:
A) chemical indicator is placed under identical conditions for sterilization together with by sterilizing objects;
B) color change of chemical indicator is observed to judge Disinfection Effect, when chemical indicator is exposed to wet oxidation
When in type disinfectant, especially in ozone when, show apparent color change;When chemical indicator is exposed to dry oxidation
When in type disinfectant or oxygen, color change does not occur.
Chemical indicator of the present invention is the composition of indication compound and ink, and this composition can be used for being coated or impregnated with
Substrate, paper are suitable substrates, and the form of narrow volume can be used by being coated or impregnated with paper, easily to tear from volume, with
Just it is used in disinfection.Coated paper or impregnated paper can be protected with transparent membrane, or paper slip can be inserted into bag, such as high
Density polyethylene synthesizes in paper bag, is exposed to indicator in disinfectant, while allowing to observe any color by transparent membrane
Variation.
There is one section of indication compound on the chemical indicator, indication compound can be combined with different devices, be formed different
Compound indicant, such as independent chemical indicator, the independent biochemical indicant comprising indication compound, challenge packet, test
Packet, adhesive tape or paster etc..
The chemical indicator forms indicator and indication compound is placed on substrate to form bar.Instruction
Band is usually by having the small pieces of material of instruction compound cross-section to form.Indicator is placed in disinfection room, is exposed to oxidized form disinfectant
In.After being exposed to the disinfectant regular hour, the indicating section original state of the chemical indicator is red, by first half
Become crocus or light orange after period, after second half of the cycle terminates or sterilizes, color obviously bleaches color or colourless, shows
The Disinfection Effect of oxidized form disinfectant especially ozone is preferable.
Claims (8)
1. a kind of chemical indicator for monitoring oxidized form disinfectant Disinfection Effect, which is characterized in that including indication compound and oil
Ink composition, the indication compound are triarylmethane dye, and the printing ink composition includes: solvent, pH adjusting agent, glues
Spend modifying agent, defoaming agent, oil base, evaporation or drying aids, the indication compound and printing ink composition mass percent are as follows: 6
~10%:90~94%, the substituent group in the triarylmethane dye structure on Ar at least contain a hydroxyl, and described three
Arylmethane dyes, which are exposed to color in oxidized form disinfectant disinfecting process, can occur significant change.
2. a kind of chemical indicator for monitoring oxidized form disinfectant Disinfection Effect according to claim 1, which is characterized in that
The indication compound is rhodizonic acid.
3. a kind of chemical indicator for monitoring oxidized form disinfectant Disinfection Effect according to claim 1, which is characterized in that
The rhodizonic acid mass percent is 6~10%.
4. a kind of chemical indicator for monitoring oxidized form disinfectant Disinfection Effect according to claim 1, which is characterized in that
The rhodizonic acid has photostability.
5. a kind of chemical indicator for monitoring oxidized form disinfectant Disinfection Effect according to claim 1, which is characterized in that
The oil base is non-foamed nonionic mineral oil, and pH adjusting agent is alkaline conditioner, and adhesive is water soluble acrylic resin, is glued
Degree regulator is hydroxyethyl cellulose, and defrother is non-ionic mineral oil, and evaporant or drying aids are with this function
Compound, solvent are water or alcohol.
6. a kind of chemical indicator for monitoring oxidized form disinfectant Disinfection Effect according to claim 5, which is characterized in that
The pH adjusting agent is sodium hydroxide or ammonia, and evaporant or drying aids are ammonia or alcohol.
7. a kind of chemical indicator for monitoring oxidized form disinfectant Disinfection Effect according to claim 1, which is characterized in that
Component of the printing ink composition with following mass percent: hydroxyethyl cellulose 2.65~3.45%, sodium hydroxide 1~
2.6%, acrylic resin 0.5~2.5%, ammonia 0.25~0.85%, non-foamed nonionic mineral oil 0.1~0.3%, water 80.3
~89.5%.
8. a kind of method for monitoring oxidized form disinfectant disinfecting process, which is characterized in that method includes the following steps:
A) chemical indicator is placed under identical conditions for sterilization together with by sterilizing objects;
B) color change of chemical indicator is observed to judge Disinfection Effect, is disappeared when chemical indicator is exposed to wet oxidized form
When in toxic agent, especially in ozone when, show apparent color change;Disappear when chemical indicator is exposed to dry oxidized form
When in toxic agent or oxygen, color change does not occur.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201910126952.0A CN109668884A (en) | 2019-02-20 | 2019-02-20 | A kind of chemical indicator and monitoring method monitoring oxidized form disinfectant Disinfection Effect |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201910126952.0A CN109668884A (en) | 2019-02-20 | 2019-02-20 | A kind of chemical indicator and monitoring method monitoring oxidized form disinfectant Disinfection Effect |
Publications (1)
Publication Number | Publication Date |
---|---|
CN109668884A true CN109668884A (en) | 2019-04-23 |
Family
ID=66152076
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201910126952.0A Pending CN109668884A (en) | 2019-02-20 | 2019-02-20 | A kind of chemical indicator and monitoring method monitoring oxidized form disinfectant Disinfection Effect |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN109668884A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112724964A (en) * | 2020-12-29 | 2021-04-30 | 优品保技术(北京)有限公司 | Disinfectant with indication and tracing functions and application thereof |
Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU383449A1 (en) * | 1971-10-20 | 1973-05-23 | INDICATOR FOR THE DETECTION OF MILK RECEIVED FROM PATIENTS WITH MASTITIS | |
CN1411496A (en) * | 1999-12-15 | 2003-04-16 | 凸板印刷株式会社 | Ink composition for detecting carbon dioxide and carbon dioxide indicator using same, and package having carbon dioxide indicator therein |
CN1890333A (en) * | 2003-10-07 | 2007-01-03 | 桑福德有限合伙人公司 | Method of highlighting with a reversible highlighting mixture, highlighting kit, and highlighted complex |
CN101166800A (en) * | 2005-04-25 | 2008-04-23 | 桑福德有限合伙人公司 | Eradicable composition and kit |
CN101268159A (en) * | 2005-08-09 | 2008-09-17 | 旭化成化学株式会社 | Ink composition and oxygen indicator |
CN101273268A (en) * | 2005-08-09 | 2008-09-24 | 芬兰技术研究中心 | Ink composition, oxygen and/or PH indicator and package |
CN103210056A (en) * | 2010-12-06 | 2013-07-17 | 金伯利-克拉克环球有限公司 | Color-changing composition |
CN105504978A (en) * | 2016-02-25 | 2016-04-20 | 深圳九星印刷包装集团有限公司 | Color change indicating device and transparent ink |
CN107793301A (en) * | 2016-08-30 | 2018-03-13 | 天津市科密欧化学试剂有限公司 | A kind of preparation method of rosolic acid |
CN108603334A (en) * | 2016-01-29 | 2018-09-28 | 富士胶片株式会社 | Ink-jet printing method, jetted ink, ink cartridge and painting cloth |
CN111220603A (en) * | 2019-10-30 | 2020-06-02 | 苏州露水生物技术有限公司 | Hydrogen peroxide sterilization detection indicator card and preparation method thereof |
-
2019
- 2019-02-20 CN CN201910126952.0A patent/CN109668884A/en active Pending
Patent Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU383449A1 (en) * | 1971-10-20 | 1973-05-23 | INDICATOR FOR THE DETECTION OF MILK RECEIVED FROM PATIENTS WITH MASTITIS | |
CN1411496A (en) * | 1999-12-15 | 2003-04-16 | 凸板印刷株式会社 | Ink composition for detecting carbon dioxide and carbon dioxide indicator using same, and package having carbon dioxide indicator therein |
CN1890333A (en) * | 2003-10-07 | 2007-01-03 | 桑福德有限合伙人公司 | Method of highlighting with a reversible highlighting mixture, highlighting kit, and highlighted complex |
CN101166800A (en) * | 2005-04-25 | 2008-04-23 | 桑福德有限合伙人公司 | Eradicable composition and kit |
CN101268159A (en) * | 2005-08-09 | 2008-09-17 | 旭化成化学株式会社 | Ink composition and oxygen indicator |
CN101273268A (en) * | 2005-08-09 | 2008-09-24 | 芬兰技术研究中心 | Ink composition, oxygen and/or PH indicator and package |
CN103210056A (en) * | 2010-12-06 | 2013-07-17 | 金伯利-克拉克环球有限公司 | Color-changing composition |
CN108603334A (en) * | 2016-01-29 | 2018-09-28 | 富士胶片株式会社 | Ink-jet printing method, jetted ink, ink cartridge and painting cloth |
CN105504978A (en) * | 2016-02-25 | 2016-04-20 | 深圳九星印刷包装集团有限公司 | Color change indicating device and transparent ink |
CN107793301A (en) * | 2016-08-30 | 2018-03-13 | 天津市科密欧化学试剂有限公司 | A kind of preparation method of rosolic acid |
CN111220603A (en) * | 2019-10-30 | 2020-06-02 | 苏州露水生物技术有限公司 | Hydrogen peroxide sterilization detection indicator card and preparation method thereof |
Non-Patent Citations (5)
Title |
---|
《简明化学试剂手册》编写组: "《简明化学试剂手册》", 31 January 1991, 上海科学技术出版社 * |
南京大学化学系有机化学教研组: "《有机化学 下册》", 31 May 1962, 人民教育出版社 * |
张鎏: "《英汉技术科学词典 精编 注释》", 31 October 1997, 化学工业出版社 * |
杨红: "《现代汉英/英汉印刷油墨词典》", 31 October 2002, 印刷工业出版社 * |
毛丽秋: "《化学研究与设计性实验》", 31 October 2008, 湖南师范大学出版社 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112724964A (en) * | 2020-12-29 | 2021-04-30 | 优品保技术(北京)有限公司 | Disinfectant with indication and tracing functions and application thereof |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US20200231930A1 (en) | Microorganism culture sheet | |
US20210038753A1 (en) | Biological sterilization indicator with sterilant resistance modulator | |
US8975067B2 (en) | Self-contained sterilization indicators including a neutralizer for residual oxidizing sterilant | |
US6790411B1 (en) | Hydrogen peroxide indicator and method | |
US20170037447A1 (en) | Biological compositions, articles and methods for monitoring sterilization processes | |
CN108107039B (en) | Peroxyacetic acid determination test paper and determination method thereof | |
US20130273594A1 (en) | Sterilization indicators including a porous carrier and methods | |
EP1163913A2 (en) | Method of monitoring sterilization and indicator therefor | |
RU2464565C2 (en) | Rapid assessment of upper airway state | |
JP2002541466A (en) | Indicators for monitoring plasma sterilization | |
CN105073146A (en) | Biological indicator for monitoring a low-temperature sterilization process | |
TW201843431A (en) | Apparatus and method to read biological indicator | |
CN109668884A (en) | A kind of chemical indicator and monitoring method monitoring oxidized form disinfectant Disinfection Effect | |
EP4034544A1 (en) | 8-fluoro-4-alkylumbelliferyl alpha-d-glucopyranoside, biological sterilization indicator including the same and its use in a method of determining efficacy of a sterilization process | |
CN101864475B (en) | Method for measuring low density lipoprotein cholesterol | |
EP0171158B1 (en) | Processes and materials for carrying out microchemical and microbiological tests | |
DK2185912T3 (en) | Indicator composition, ink formulation and integrated chemical indicator device | |
US11696969B2 (en) | Ethylene oxide treatment indicator, label and method of use | |
CN115315522A (en) | Fixed pH indicator for biological indicator growth indication | |
EP2562169B1 (en) | Tetrazolium compound for detecting microorganisms, reagent for detecting microorganisms and method for detecting microorganisms | |
JP2005287452A (en) | Method for culturing/detecting microorganism and coloring reagent for detecting microorganism | |
US20230193347A1 (en) | Biological Indicator with Test Microorganisms Enveloped by Wax Composition | |
SK285393B6 (en) | Steam sterilization process indicator | |
CN114981399A (en) | Self-contained biological indicator with salt compound | |
Cloete, TE, Da Silva, E. & Brozel | Application of Sterikon bioindicators for the determination of bactericide concentrations |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190423 |