CN109668884A - A kind of chemical indicator and monitoring method monitoring oxidized form disinfectant Disinfection Effect - Google Patents

A kind of chemical indicator and monitoring method monitoring oxidized form disinfectant Disinfection Effect Download PDF

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Publication number
CN109668884A
CN109668884A CN201910126952.0A CN201910126952A CN109668884A CN 109668884 A CN109668884 A CN 109668884A CN 201910126952 A CN201910126952 A CN 201910126952A CN 109668884 A CN109668884 A CN 109668884A
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chemical indicator
oxidized form
disinfection effect
monitoring
exposed
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胡志超
姬君君
郑晓静
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Henan Fangzhou Medical Devices Co Ltd
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Henan Fangzhou Medical Devices Co Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/775Indicator and selective membrane

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

Abstract

The invention discloses a kind of chemical indicators for monitoring oxidized form disinfectant Disinfection Effect, including indication compound and printing ink composition, the indication compound is triarylmethane dye, the indication compound and printing ink composition mass percent are as follows: 6~10%:90~94%, the triarylmethane dye, which is exposed to color in oxidized form disinfectant disinfecting process, can occur significant change.A method of monitoring oxidized form disinfectant disinfecting process, method includes the following steps: chemical indicator is placed under identical conditions for sterilization together with by sterilizing objects;The color change for observing chemical indicator judges Disinfection Effect, when chemical indicator is exposed in wet oxidized form disinfectant, especially in ozone when, show apparent color change;When chemical indicator is exposed in dry oxidized form disinfectant or oxygen, color change does not occur.Chemical indicator monitoring disinfection result of the present invention is quickly and color instruction variation is obvious, has preferable indicative function.

Description

A kind of chemical indicator and monitoring method monitoring oxidized form disinfectant Disinfection Effect
Technical field
The invention belongs to chemical indicator technical field more particularly to a kind of changes for monitoring oxidized form disinfectant Disinfection Effect Learn indicator and monitoring method.
Background technique
Disinfection is all in need in many fields, especially medical domain.Ozone is a kind of oxidized form disinfectant, disinfection effect Fruit will receive the influence of the factors such as humidity, temperature.Ozone can carry out sterilizing in low temperature or at room temperature, and ozone is in height Temperature is lower to be easy to decompose, so ozone is not need high temperature in disinfection, this is an advantage of ozonization.Certainly, it monitors smelly It is also highly important that whether the disinfecting process of oxygen, which reaches Disinfection Effect,.
Chemical indicator design principle is to occur to have characteristic according to one or more physical conditions in sterilizing cabin Color change.Chemical indicator is usually used in combination with other sterilization monitor devices, is exposed in sterilizing cabin.According to routine, Biological indicator is placed in sterilizing cabin to monitor Disinfection Effect, biological indicator is made of the bacterium item containing a large amount of microorganisms , after sanitized, bacterium item is cultivated, observes microorganism growing state, judges whether disinfection succeeds.If using this Mode monitors Disinfection Effect, and disinfection result need to wait at least for 24 hours, is unfavorable for the development of follow-up work in this way.Therefore, it is necessary to There is a kind of method quickly to monitor disinfection situation.
The object of the present invention is to provide a kind of in the disinfecting process of oxidized form disinfectant, especially in ozone disinfection process The indicator and method of Disinfection Effect are monitored, and can quickly monitor disinfection situation.
Summary of the invention
It is an object of the invention to: Disinfection Effect is monitored using traditional bionidicator for above-mentioned, sterilizes result The problem of need to waiting at least for 24 hours, being unfavorable for the development of follow-up work, the present invention provide a kind of monitoring oxidized form disinfectant and disappear The chemical indicator and monitoring method of toxic effect fruit.
The technical solution adopted by the invention is as follows:
A kind of chemical indicator monitoring oxidized form disinfectant Disinfection Effect, including indication compound and printing ink composition, The indication compound be triarylmethane dye, the printing ink composition include: solvent, pH adjusting agent, viscosity modifier, Defoaming agent, oil base, evaporation or drying aids, the indication compound and printing ink composition mass percent are as follows: 6~10%:90 ~94%, the triarylmethane dye structural formula are as follows:
Ar is substituted or unsubstituted aryl, and Ar' is cyclohexadienyl substituted or unsubstituted, and wherein Ar is phenyl or substitution Phenyl, the substituent group on Ar include hydroxyl, halogen (such as bromine or chlorine), lower alkyl (such as methyl, ethyl or isopropyl), sulfonate and Carboxyl, the triarylmethane dye, which is exposed to color in oxidized form disinfectant disinfecting process, can occur significant change.
As a preferred mode, the substituent group in the triarylmethane dye structure on Ar at least contains one Hydroxyl.
As a preferred mode, the indication compound is rhodizonic acid.This indication compound is not only in ozone It can change colour in disinfecting process, and dual visible change can be showed in the disinfecting process of two half periods.At the beginning of the compound Beginning state is red, becomes crocus or light orange, after second half of the cycle terminates or sterilizes, face after preceding half period Color obviously bleaches color or colourless.
As a preferred mode, the indication compound has photostability.Indication compound is especially to fluorescence Lamp and sunlight have photostability, and such chemical indicator will not be by shadow long-time is exposed to color change under light It rings.
As a preferred mode, the oil base is non-foamed nonionic mineral oil, and pH adjusting agent is alkaline conditioner, Adhesive is water soluble acrylic resin, and viscosity modifier is hydroxyethyl cellulose, and defrother is non-ionic mineral oil, evaporation Agent or drying aids are compound with this function, and solvent is water or alcohol.
As a preferred mode, the pH adjusting agent is sodium hydroxide or ammonia, evaporant or drying aids be ammonia or Alcohol.
As a preferred mode, the printing ink composition has the component of following mass percent: hydroxy ethyl fiber Element 2.65~3.45%, sodium hydroxide 1~2.6%, acrylic resin 0.5~2.5%, ammonia 0.25~0.85%, non-foamed is non- Ion mineral oil 0.1~0.3%, water 80.3~89.5%.
A method of monitoring oxidized form disinfectant disinfecting process, method includes the following steps:
A) chemical indicator is placed under identical conditions for sterilization together with by sterilizing objects;
B) color change of chemical indicator is observed to judge Disinfection Effect, when chemical indicator is exposed to wet oxidation When in type disinfectant, especially in ozone when, show apparent color change;When chemical indicator is exposed to dry oxidation When in type disinfectant or oxygen, color change does not occur.
Chemical indicator of the present invention is the composition of indication compound and ink, and this composition can be used for being coated or impregnated with Substrate, paper are suitable substrates, and the form of narrow volume can be used by being coated or impregnated with paper, easily to tear from volume, with Just it is used in disinfection.Coated paper or impregnated paper can be protected with transparent membrane, or paper slip can be inserted into bag, such as high Density polyethylene synthesizes in paper bag, is exposed to indicator in disinfectant, while allowing to observe any color by transparent membrane Variation.
There is one section of indication compound on the chemical indicator, indication compound can be combined with different devices, be formed different Compound indicant, such as independent chemical indicator, the independent biochemical indicant comprising indication compound, challenge packet, test Packet, adhesive tape or paster etc..
The chemical indicator forms indicator and indication compound is placed on substrate to form bar.Instruction Band is usually by having the small pieces of material of instruction compound cross-section to form.Indicator is placed in disinfection room, is exposed to oxidized form disinfectant In.After being exposed to the disinfectant regular hour, the indicating section of the chemical indicator has color change.
In conclusion by adopting the above-described technical solution, the beneficial effects of the present invention are:
1. the present invention judges the packaged form that chemical indicator can be made into diversified forms by the disinfection of sterilizing objects Effect, monitoring result is quickly and color instruction variation is obvious, has preferable indicative function, simple judgment Disinfection Effect, operation Method is simple, saves detection time and cost, high sensitivity, meets to supervising in oxidized form disinfectant especially ozone disinfection process Survey the demand of Disinfection Effect.
Specific embodiment
All features disclosed in this specification or disclosed all methods or in the process the step of, in addition to mutually exclusive Feature and/or step other than, can combine in any way.
Embodiment 1
A kind of chemical indicator monitoring oxidized form disinfectant Disinfection Effect, including indication compound and printing ink composition, The indication compound be triarylmethane dye, the printing ink composition include: solvent, pH adjusting agent, viscosity modifier, Defoaming agent, oil base, evaporation or drying aids, the indication compound and printing ink composition mass percent are as follows: 6~10%:90 ~94%, the triarylmethane dye structural formula are as follows:
Ar is substituted or unsubstituted aryl, and Ar' is cyclohexadienyl substituted or unsubstituted, and wherein Ar is phenyl or substitution Phenyl, the substituent group on Ar include hydroxyl, halogen (such as bromine or chlorine), lower alkyl (such as methyl, ethyl or isopropyl), sulfonate and Carboxyl, the triarylmethane dye, which is exposed to color in oxidized form disinfectant disinfecting process, can occur significant change.
As a preferred mode, the substituent group in the triarylmethane dye structure on Ar at least contains one Hydroxyl.
As a preferred mode, the indication compound is rhodizonic acid.This indication compound is not only in ozone It can change colour in disinfecting process, and dual visible change can be showed in the disinfecting process of two half periods.At the beginning of the compound Beginning state is red, becomes crocus or light orange, after second half of the cycle terminates or sterilizes, face after preceding half period Color obviously bleaches color or colourless.
As a preferred mode, the indication compound has photostability.Indication compound is especially to fluorescence Lamp and sunlight have photostability, and such chemical indicator will not be by shadow long-time is exposed to color change under light It rings.
As a preferred mode, the oil base is non-foamed nonionic mineral oil, and pH adjusting agent is alkaline conditioner, Adhesive is water soluble acrylic resin, and viscosity modifier is hydroxyethyl cellulose, and defrother is non-ionic mineral oil, evaporation Agent or drying aids are compound with this function, and solvent is water or alcohol.
As a preferred mode, the pH adjusting agent is sodium hydroxide or ammonia, evaporant or drying aids be ammonia or Alcohol.
As a preferred mode, the printing ink composition has the component of following mass percent: hydroxy ethyl fiber Element 2.65~3.45%, sodium hydroxide 1~2.6%, acrylic resin 0.5~2.5%, ammonia 0.25~0.85%, non-foamed is non- Ion mineral oil 0.1~0.3%, water 80.3~89.5%.
A method of monitoring oxidized form disinfectant disinfecting process, method includes the following steps:
A) chemical indicator is placed under identical conditions for sterilization together with by sterilizing objects;
B) color change of chemical indicator is observed to judge Disinfection Effect, when chemical indicator is exposed to wet oxidation When in type disinfectant, especially in ozone when, show apparent color change;When chemical indicator is exposed to dry oxidation When in type disinfectant or oxygen, color change does not occur.
Chemical indicator of the present invention is the composition of indication compound and ink, and this composition can be used for being coated or impregnated with Substrate, paper are suitable substrates, and the form of narrow volume can be used by being coated or impregnated with paper, easily to tear from volume, with Just it is used in disinfection.Coated paper or impregnated paper can be protected with transparent membrane, or paper slip can be inserted into bag, such as high Density polyethylene synthesizes in paper bag, is exposed to indicator in disinfectant, while allowing to observe any color by transparent membrane Variation.
There is one section of indication compound on the chemical indicator, indication compound can be combined with different devices, be formed different Compound indicant, such as independent chemical indicator, the independent biochemical indicant comprising indication compound, challenge packet, test Packet, adhesive tape or paster etc..
The chemical indicator forms indicator and indication compound is placed on substrate to form bar.Instruction Band is usually by having the small pieces of material of instruction compound cross-section to form.Indicator is placed in disinfection room, is exposed to oxidized form disinfectant In.After being exposed to the disinfectant regular hour, the indicating section of the chemical indicator has color change.
Applicability detection indication compound is carried out to a large amount of indication compound and monitors oxidized form disinfectant, especially ozone The process of disinfection assesses chemical indicator in terms of three: color acceptability, color change, colour stable.
Color acceptability refers to the acceptability of first color state.For certain indication compounds, initial color It is not deep or too pale enough, color acceptable assessment is carried out to triarylmethane representation compound, as a result as shown in table 1 below.
The color of 1 triarylmethane representativeness indication compound of table is acceptable
Color designation Color It is acceptable
Phenol red It is red It is acceptable
Rhodizonic acid It is red It is acceptable
It therefore, can be using phenol red, rhodizonic acid as the candidate of indication compound according to color acceptability.
In addition, also important, the chemical indicator and oxygen do not occur when contacting color change or with disinfection When color change it is different.Otherwise, it may not distinguish not Chu Lai disinfection when ozone validity, can to chemical indicator into Row oxygen rinses, to exclude the interference of oxygen.
The test-strips of phenol red, rhodizonic acid indication compound are exposed in the sterilizing cabin containing wet ozone, It is tested in dry ozone and wet oxygen, test result is as follows shown in table 2:
2 phenol red of table, rhodizonic acid indication compound are tested in the ozone and wet oxygen of the ozone, drying that moisten As a result
Indication compound title Before disinfection After half period After the completion of period Ozone without humidity There is the oxygen of humidity
Rhodizonic acid (8%) It is red Shallow orange It is colourless Deep orange It is red
Rhodizonic acid (1%) It is red Crocus It is colourless Lightpink Rouge and powder color
Phenol red Chinese red It is colourless It is colourless Crocus Crocus
Indication compound described in table 2 and printing ink composition are coated on paper and are dried, in order to heighten the color two layers of painting, then The paper slip of coated two layers of printing ink composition is handled as follows:
Chemical indicator test strip is exposed under autoclave and illumination respectively and is placed 21 days, as a result test is as shown in table 3:
3 phenol red of table, rhodizonic acid the chemical indicator test result under autoclave and illumination
Dye title Autoclave Lamp
Rhodizonic acid (8%) Without color change Without color change
Rhodizonic acid (1%) Without color change Without color change
Phenol red Without color change It fades under light
, can be using rhodizonic acid as indication compound according to table 2,3 result of table, but rhodizonic acid content also has one Determine section.
Embodiment 2
A kind of chemical indicator monitoring oxidized form disinfectant Disinfection Effect, including indication compound and printing ink composition, The indication compound is rhodizonic acid, and the printing ink composition includes: solvent, pH adjusting agent, viscosity modifier, skimming Agent, oil base, evaporation or drying aids, the chemical indicator mass percent are as follows: rhodizonic acid 6%, hydroxyethyl cellulose 2.65%, sodium hydroxide 1%, acrylic resin 0.5%, ammonia 0.25%, non-foamed nonionic mineral oil 0.1%, water 89.5%, The rhodizonic acid dyestuff, which is exposed to color in oxidized form disinfectant disinfecting process, can occur significant change.
As a preferred mode, the indication compound can not only change colour in ozone disinfection process, but also two Dual visible change can be showed in the disinfecting process of a half period.The compound original state was red, by first half week Become crocus or light orange after phase, after second half of the cycle terminates or sterilizes, color obviously bleaches color or colourless.
As a preferred mode, the indication compound has photostability.Indication compound is especially to fluorescence Lamp and sunlight have photostability, and such chemical indicator will not be by shadow long-time is exposed to color change under light It rings.
A method of monitoring oxidized form disinfectant disinfecting process, method includes the following steps:
A) chemical indicator is placed under identical conditions for sterilization together with by sterilizing objects;
B) color change of chemical indicator is observed to judge Disinfection Effect, when chemical indicator is exposed to wet oxidation When in type disinfectant, especially in ozone when, show apparent color change;When chemical indicator is exposed to dry oxidation When in type disinfectant or oxygen, color change does not occur.
Chemical indicator of the present invention is the composition of indication compound and ink, and this composition can be used for being coated or impregnated with Substrate, paper are suitable substrates, and the form of narrow volume can be used by being coated or impregnated with paper, easily to tear from volume, with Just it is used in disinfection.Coated paper or impregnated paper can be protected with transparent membrane, or paper slip can be inserted into bag, such as high Density polyethylene synthesizes in paper bag, is exposed to indicator in disinfectant, while allowing to observe any color by transparent membrane Variation.
There is one section of indication compound on the chemical indicator, indication compound can be combined with different devices, be formed different Compound indicant, such as independent chemical indicator, the independent biochemical indicant comprising indication compound, challenge packet, test Packet, adhesive tape or paster etc..
The chemical indicator forms indicator and indication compound is placed on substrate to form bar.Instruction Band is usually by having the small pieces of material of instruction compound cross-section to form.Indicator is placed in disinfection room, is exposed to oxidized form disinfectant In.After being exposed to the disinfectant regular hour, the indicating section original state of the chemical indicator is red, by first half Become crocus or light orange after period, after second half of the cycle terminates or sterilizes, color obviously bleaches color or colourless, shows The Disinfection Effect of oxidized form disinfectant especially ozone is preferable.
Embodiment 3
A kind of chemical indicator monitoring oxidized form disinfectant Disinfection Effect, including indication compound and printing ink composition, The indication compound is rhodizonic acid, and the printing ink composition includes: solvent, pH adjusting agent, viscosity modifier, skimming Agent, oil base, evaporation or drying aids, the chemical indicator mass percent are as follows: rhodizonic acid 10%, hydroxyethyl cellulose 3.45%, sodium hydroxide 2.6%, acrylic resin 2.5%, ammonia 0.85%, non-foamed nonionic mineral oil 0.3%, water 80.3%, the rhodizonic acid dyestuff, which is exposed to color in oxidized form disinfectant disinfecting process, can occur significant change.
As a preferred mode, the indication compound can not only change colour in ozone disinfection process, but also two Dual visible change can be showed in the disinfecting process of a half period.The compound original state was red, by first half week Become crocus or light orange after phase, after second half of the cycle terminates or sterilizes, color obviously bleaches color or colourless.
As a preferred mode, the indication compound has photostability.Indication compound is especially to fluorescence Lamp and sunlight have photostability, and such chemical indicator will not be by shadow long-time is exposed to color change under light It rings.
A method of monitoring oxidized form disinfectant disinfecting process, method includes the following steps:
A) chemical indicator is placed under identical conditions for sterilization together with by sterilizing objects;
B) color change of chemical indicator is observed to judge Disinfection Effect, when chemical indicator is exposed to wet oxidation When in type disinfectant, especially in ozone when, show apparent color change;When chemical indicator is exposed to dry oxidation When in type disinfectant or oxygen, color change does not occur.
Chemical indicator of the present invention is the composition of indication compound and ink, and this composition can be used for being coated or impregnated with Substrate, paper are suitable substrates, and the form of narrow volume can be used by being coated or impregnated with paper, easily to tear from volume, with Just it is used in disinfection.Coated paper or impregnated paper can be protected with transparent membrane, or paper slip can be inserted into bag, such as high Density polyethylene synthesizes in paper bag, is exposed to indicator in disinfectant, while allowing to observe any color by transparent membrane Variation.
There is one section of indication compound on the chemical indicator, indication compound can be combined with different devices, be formed different Compound indicant, such as independent chemical indicator, the independent biochemical indicant comprising indication compound, challenge packet, test Packet, adhesive tape or paster etc..
The chemical indicator forms indicator and indication compound is placed on substrate to form bar.Instruction Band is usually by having the small pieces of material of instruction compound cross-section to form.Indicator is placed in disinfection room, is exposed to oxidized form disinfectant In.After being exposed to the disinfectant regular hour, the indicating section original state of the chemical indicator is red, by first half Become crocus or light orange after period, after second half of the cycle terminates or sterilizes, color obviously bleaches color or colourless, shows The Disinfection Effect of oxidized form disinfectant especially ozone is preferable.
Embodiment 4
A kind of chemical indicator monitoring oxidized form disinfectant Disinfection Effect, including indication compound and printing ink composition, The indication compound is rhodizonic acid, and the printing ink composition includes: solvent, pH adjusting agent, viscosity modifier, skimming Agent, oil base, evaporation or drying aids, the chemical indicator mass percent are as follows: rhodizonic acid 8%, hydroxyethyl cellulose 3.15%, sodium hydroxide 1.8%, acrylic resin 1.5%, ammonia 0.45%, non-foamed nonionic mineral oil 0.2%, water 84.9%, the rhodizonic acid dyestuff, which is exposed to color in oxidized form disinfectant disinfecting process, can occur significant change.
As a preferred mode, the indication compound can not only change colour in ozone disinfection process, but also two Dual visible change can be showed in the disinfecting process of a half period.The compound original state was red, by first half week Become crocus or light orange after phase, after second half of the cycle terminates or sterilizes, color obviously bleaches color or colourless.
As a preferred mode, the indication compound has photostability.Indication compound is especially to fluorescence Lamp and sunlight have photostability, and such chemical indicator will not be by shadow long-time is exposed to color change under light It rings.
A method of monitoring oxidized form disinfectant disinfecting process, method includes the following steps:
A) chemical indicator is placed under identical conditions for sterilization together with by sterilizing objects;
B) color change of chemical indicator is observed to judge Disinfection Effect, when chemical indicator is exposed to wet oxidation When in type disinfectant, especially in ozone when, show apparent color change;When chemical indicator is exposed to dry oxidation When in type disinfectant or oxygen, color change does not occur.
Chemical indicator of the present invention is the composition of indication compound and ink, and this composition can be used for being coated or impregnated with Substrate, paper are suitable substrates, and the form of narrow volume can be used by being coated or impregnated with paper, easily to tear from volume, with Just it is used in disinfection.Coated paper or impregnated paper can be protected with transparent membrane, or paper slip can be inserted into bag, such as high Density polyethylene synthesizes in paper bag, is exposed to indicator in disinfectant, while allowing to observe any color by transparent membrane Variation.
There is one section of indication compound on the chemical indicator, indication compound can be combined with different devices, be formed different Compound indicant, such as independent chemical indicator, the independent biochemical indicant comprising indication compound, challenge packet, test Packet, adhesive tape or paster etc..
The chemical indicator forms indicator and indication compound is placed on substrate to form bar.Instruction Band is usually by having the small pieces of material of instruction compound cross-section to form.Indicator is placed in disinfection room, is exposed to oxidized form disinfectant In.After being exposed to the disinfectant regular hour, the indicating section original state of the chemical indicator is red, by first half Become crocus or light orange after period, after second half of the cycle terminates or sterilizes, color obviously bleaches color or colourless, shows The Disinfection Effect of oxidized form disinfectant especially ozone is preferable.

Claims (8)

1. a kind of chemical indicator for monitoring oxidized form disinfectant Disinfection Effect, which is characterized in that including indication compound and oil Ink composition, the indication compound are triarylmethane dye, and the printing ink composition includes: solvent, pH adjusting agent, glues Spend modifying agent, defoaming agent, oil base, evaporation or drying aids, the indication compound and printing ink composition mass percent are as follows: 6 ~10%:90~94%, the substituent group in the triarylmethane dye structure on Ar at least contain a hydroxyl, and described three Arylmethane dyes, which are exposed to color in oxidized form disinfectant disinfecting process, can occur significant change.
2. a kind of chemical indicator for monitoring oxidized form disinfectant Disinfection Effect according to claim 1, which is characterized in that The indication compound is rhodizonic acid.
3. a kind of chemical indicator for monitoring oxidized form disinfectant Disinfection Effect according to claim 1, which is characterized in that The rhodizonic acid mass percent is 6~10%.
4. a kind of chemical indicator for monitoring oxidized form disinfectant Disinfection Effect according to claim 1, which is characterized in that The rhodizonic acid has photostability.
5. a kind of chemical indicator for monitoring oxidized form disinfectant Disinfection Effect according to claim 1, which is characterized in that The oil base is non-foamed nonionic mineral oil, and pH adjusting agent is alkaline conditioner, and adhesive is water soluble acrylic resin, is glued Degree regulator is hydroxyethyl cellulose, and defrother is non-ionic mineral oil, and evaporant or drying aids are with this function Compound, solvent are water or alcohol.
6. a kind of chemical indicator for monitoring oxidized form disinfectant Disinfection Effect according to claim 5, which is characterized in that The pH adjusting agent is sodium hydroxide or ammonia, and evaporant or drying aids are ammonia or alcohol.
7. a kind of chemical indicator for monitoring oxidized form disinfectant Disinfection Effect according to claim 1, which is characterized in that Component of the printing ink composition with following mass percent: hydroxyethyl cellulose 2.65~3.45%, sodium hydroxide 1~ 2.6%, acrylic resin 0.5~2.5%, ammonia 0.25~0.85%, non-foamed nonionic mineral oil 0.1~0.3%, water 80.3 ~89.5%.
8. a kind of method for monitoring oxidized form disinfectant disinfecting process, which is characterized in that method includes the following steps:
A) chemical indicator is placed under identical conditions for sterilization together with by sterilizing objects;
B) color change of chemical indicator is observed to judge Disinfection Effect, is disappeared when chemical indicator is exposed to wet oxidized form When in toxic agent, especially in ozone when, show apparent color change;Disappear when chemical indicator is exposed to dry oxidized form When in toxic agent or oxygen, color change does not occur.
CN201910126952.0A 2019-02-20 2019-02-20 A kind of chemical indicator and monitoring method monitoring oxidized form disinfectant Disinfection Effect Pending CN109668884A (en)

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Cited By (1)

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CN112724964A (en) * 2020-12-29 2021-04-30 优品保技术(北京)有限公司 Disinfectant with indication and tracing functions and application thereof

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Application publication date: 20190423