CN109646592A - It is a kind of suitable for irritable cough and the Chinese medicine composition and Chinese materia medica preparation of acute and chronic pharyngitis - Google Patents

It is a kind of suitable for irritable cough and the Chinese medicine composition and Chinese materia medica preparation of acute and chronic pharyngitis Download PDF

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Publication number
CN109646592A
CN109646592A CN201910075702.9A CN201910075702A CN109646592A CN 109646592 A CN109646592 A CN 109646592A CN 201910075702 A CN201910075702 A CN 201910075702A CN 109646592 A CN109646592 A CN 109646592A
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parts
radix
chinese medicine
medicine composition
acute
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CN201910075702.9A
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冯永晟
陈京津
杨建课
董洪良
朱红
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Wannan Medical College
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Wannan Medical College
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Abstract

The invention discloses a kind of suitable for irritable cough and the Chinese medicine composition and Chinese materia medica preparation of acute and chronic pharyngitis, including following raw material: peppermint, Rhizoma Atractylodis Macrocephalae, bulbus fritillariae cirrhosae, dried orange peel, Radix Paeoniae Alba, fuling peel, asparagus fern, dendrobium nobile, dark plum, jujube, Radix Isatidis, old ramulus mori, chrysanthemum, coltsfoot, Radix Ophiopogonis, bryozoatum, the sterculia seed, loguat leaf, wild chrysanthemum, it is Rhododendron dauricum, honeysuckle, campanulaceae, creeping dichondra herb, Fructus Forsythiae, mulberry leaf, purple perilla, roxburgh anoectochilus terminal bud, dandelion, fennel seeds, radix bupleuri, cortex cinnamomi, Radix Glycyrrhizae, Gorgon fruit, caulis bambusae in taenian, fritillaria thunbergii, Rhizoma Chuanxiong, catechu, terminalia flesh, glutinous rehmannia, corydlis bungeana, Herba Andrographitis, Radix Astragali, the fleece-flower root, concha meretricis seu cylinae.Traditional Chinese medicine composition formula provided by the invention all uses pure plant Chinese herbal medicine to develop, without any side effects, nonirritant, and property is mild, and more patients can be allowed acceptant.And effect is prominent, should not recur after healing.This product can be made into the oral preparation product of diversified forms, overcome the disadvantages of traditional decoction mouthfeel is bad.

Description

It is a kind of suitable for irritable cough and the Chinese medicine composition and Chinese medicine of acute and chronic pharyngitis Preparation
Technical field
The invention belongs to technical field of traditional Chinese medicine, and in particular to one kind is suitable for irritable cough and acute and chronic throat Scorching Chinese medicine composition and Chinese materia medica preparation.
Background technique
Existing western medical treatment irritable cough, acute and chronic pharyngitis is mainly based on anti-inflammatory.Chronic pharyngitis is due to modern society Understand fast pace, majority are fond of drinking, and smoke, it has also become a kind of young man's multiple diseases, irritable cough are often slow with urgency Property sphagitis is broken out simultaneously.Doctor trained in Western medicine anti-inflammatory adds cough-relieving treatment method although quick, but is used for a long time and will cause drug resistance, patient Using effect is gradually undesirable, and doctor trained in Western medicine is palliative, and autumn and winter temperature is gradually cool, which the high-incidence season occurs, uses west Cure treat generally require it is repeated multiple times, it is costly.
Western medical treatment irritable cough and the commonly used Multiple Classes of Antibiotics of acute and chronic pharyngitis are invalid, film making or CT examination without It is obvious abnormal.The allergic rhinitis symptoms such as the combinable sneezing of 40% patient, rhinorrhea.Pharyngitis is pharyngeal to check visible pharyngeal fill Blood, pharynx rear wall mucous membrane surface can see there are many expand capillary and a small amount of folliculosis.The direct larynx of laryngitis sticks mirror It checking, chronic simple laryngitis patient's multilist shows throat's mucous membrane hyperemia, and vocal cords tarnish, the blood vessel of expansion is distributed with thereon, Mucous secretions increase;The state of an illness into any aggravate development be INVENTIONChronic proliferative laryngitis when, mucous membrane is obviously thickened in kermesinus, side Edge plumpness is round in print, and pronunciation is in dysraphism often, and ventricular band of larynx is often thickened because of compensatory activity;Atrophic laryngitis is less See, the crust of yellow green is often brought up after cough, and there is scorching hot or pain in throat.
Irritable cough is also referred to as allergic bronchitis or cough variant asthma, the Clinical symptoms of allergic cough It is: is more than bimestrial causeless chronic cough, cough is in paroxysmal irritation dry cough.
Chinese medicine thinks, irritable cough, acute and chronic pharyngitis mostly by ferritic lung-kidney deficiency or anemopyretic laryngalgia recurrent exerbation, Remaining evil retention is unclear, hurts saliva consumption liquid, makes consumption of yin-fluid, throat loses in supporting, furthermore in the fire of deficiency type, so as to cause the occurrence of this disease
By long-felt, theory of medicine thinks that traditional medicine therapeutic effect is more preferable, and low-cost, method is simple, is not easy Recurrent exerbation.
Summary of the invention
The purpose of the present invention is to provide a kind of Chinese medicine composition suitable for irritable cough and acute and chronic pharyngitis and Chinese materia medica preparation, containing there are many clearing heat and detoxicating, throat-benefiting drug, and be added it is a variety of fill blood, mildness drug overcomes heat-clearing Removing toxic substances, throat-benefiting.
The technical scheme adopted by the invention is as follows:
It is a kind of suitable for irritable cough and the Chinese medicine composition of acute and chronic pharyngitis, the raw material including following parts by weight: 5-8 parts of peppermint, 3-6 parts of Rhizoma Atractylodis Macrocephalae, 3-5 parts of bulbus fritillariae cirrhosae, 2-4 parts of dried orange peel, 3-5 parts of Radix Paeoniae Alba, 4-6 parts of fuling peel, 3-5 parts of asparagus fern, stone 5-7 parts of dry measure used in former times, 3-5 parts of dark plum, 10-15 parts of jujube, 5-8 parts of Radix Isatidis, old ramulus mori 3-4 parts, 4-6 parts of chrysanthemum, 3-6 parts of coltsfoot, wheat It is winter 8-10 part, 3-5 parts of bryozoatum, 8-10 parts of the sterculia seed, 5-7 parts of loguat leaf, 4-6 parts of wild chrysanthemum, 4-7 parts Rhododendron dauricum, honeysuckle 5-8 parts, 4-7 parts of campanulaceae, 2-5 parts of creeping dichondra herb, 5-8 parts of Fructus Forsythiae, 3-6 parts of mulberry leaf, 5-8 parts of purple perilla, 3-6 parts of roxburgh anoectochilus terminal bud, Pu Gong 4-7 parts of English, 2-4 parts of fennel seeds, 6-10 parts of radix bupleuri, 3-5 parts of cortex cinnamomi, 6-10 parts of Radix Glycyrrhizae, 4-6 parts of Gorgon fruit, 6-8 parts of caulis bambusae in taenian, bulb of thunberg fritillary It is 5-8 parts female, it is 6-10 parts of Rhizoma Chuanxiong, 3-7 parts of catechu, 2-5 parts of terminalia flesh, 6-8 parts of glutinous rehmannia, 5-7 parts of corydlis bungeana, 5-7 parts of Herba Andrographitis, yellow 2-5 parts of stilbene, 10-12 parts of the fleece-flower root, 9-13 parts of concha meretricis seu cylinae.
Further, it is preferable to be the raw material for including following parts by weight: 8 parts of peppermint, 4 parts of Rhizoma Atractylodis Macrocephalae, 5 parts of bulbus fritillariae cirrhosae, dried orange peel 4 Part, 3 parts of Radix Paeoniae Alba, 5 parts of fuling peel, 5 parts of asparagus fern, 5 parts of dendrobium nobile, 4 parts of dark plum, 15 parts of jujube, 8 parts of Radix Isatidis, 4 parts of old ramulus mori is yellow Spend 4 parts, 6 parts of coltsfoot, 10 parts of Radix Ophiopogonis, 5 parts of bryozoatum, 8 parts of the sterculia seed, 6 parts of loguat leaf, 4 parts of wild chrysanthemum, Rhododendron dauricum 4 parts, gold and silver Spend 8 parts, 7 parts of campanulaceae, 3 parts of creeping dichondra herb, 8 parts of Fructus Forsythiae, 3 parts of mulberry leaf, 6 parts of purple perilla, 3 parts of roxburgh anoectochilus terminal bud, 4 parts of dandelion, fennel seeds 4 Part, 10 parts of radix bupleuri, 3 parts of cortex cinnamomi, 10 parts of Radix Glycyrrhizae, 6 parts of Gorgon fruit, 6 parts of caulis bambusae in taenian, 8 parts of fritillaria thunbergii, 6 parts of Rhizoma Chuanxiong, 3 parts of catechu, terminalia flesh 2 parts, 6 parts of glutinous rehmannia, 5 parts of corydlis bungeana, 7 parts of Herba Andrographitis, 2 parts of Radix Astragali, 12 parts of the fleece-flower root, 10 parts of concha meretricis seu cylinae.
Further, it is preferable to be the raw material for including following parts by weight: 5 parts of peppermint, 6 parts of Rhizoma Atractylodis Macrocephalae, 3 parts of bulbus fritillariae cirrhosae, dried orange peel 3 Part, 4 parts of Radix Paeoniae Alba, 6 parts of fuling peel, 4 parts of asparagus fern, 6 parts of dendrobium nobile, 5 parts of dark plum, 12 parts of jujube, 7 parts of Radix Isatidis, 3 parts of old ramulus mori is yellow Spend 5 parts, 4 parts of coltsfoot, 9 parts of Radix Ophiopogonis, 4 parts of bryozoatum, 9 parts of the sterculia seed, 7 parts of loguat leaf, 5 parts of wild chrysanthemum, Rhododendron dauricum 6 parts, gold and silver Spend 6 parts, 5 parts of campanulaceae, 4 parts of creeping dichondra herb, 7 parts of Fructus Forsythiae, 5 parts of mulberry leaf, 7 parts of purple perilla, 4 parts of roxburgh anoectochilus terminal bud, 6 parts of dandelion, fennel seeds 3 Part, radix bupleuri 6,4 parts of cortex cinnamomi, 8 parts of Radix Glycyrrhizae, 4 parts of Gorgon fruit, 7 parts of caulis bambusae in taenian, 7 parts of fritillaria thunbergii, 8 parts of Rhizoma Chuanxiong, 5 parts of catechu, 4 parts of terminalia flesh, 7 parts of glutinous rehmannia, 6 parts of corydlis bungeana, 6 parts of Herba Andrographitis, 4 parts of Radix Astragali, 10 parts of the fleece-flower root, 12 parts of of concha meretricis seu cylinae
The present invention also provides the preparation method for the Chinese medicine composition for being suitable for irritable cough and acute and chronic pharyngitis, institutes State preparation method the following steps are included:
(1) by the peppermint of formula ratio, Rhizoma Atractylodis Macrocephalae, bulbus fritillariae cirrhosae, dried orange peel, Radix Paeoniae Alba, fuling peel, asparagus fern, Shi Kui, dark plum, Radix Isatidis, Old ramulus mori, chrysanthemum, coltsfoot, Radix Ophiopogonis, the sterculia seed, loguat leaf, wild chrysanthemum is Rhododendron dauricum, honeysuckle, campanulaceae, creeping dichondra herb, Fructus Forsythiae, Mulberry leaf, purple perilla, roxburgh anoectochilus terminal bud, dandelion, fennel seeds, radix bupleuri, cortex cinnamomi, Radix Glycyrrhizae, Gorgon fruit, caulis bambusae in taenian, fritillaria thunbergii, rhizome of chuanxiong, catechu, myrobalan Meat, glutinous rehmannia, corydlis bungeana, Herba Andrographitis, Radix Astragali mixing add water to cook, filter, collect filtrate A and filter residue;
(2) filter residue adds water to decoct repeatedly once, and filtering collects liquor B, it is merged with filtrate A, obtains liquor C;
(3) jujube of formula ratio is mixed with the fleece-flower root, is added water to cook, gained filtrate merges with liquor C, obtains filtrate D;
(4) filtrate D be concentrated, be dry, pulverized, obtaining powder E;
(5) it is mixed after crushing the bryozoatum of formula ratio with concha meretricis seu cylinae with powder E, the Chinese medicine composition can be obtained.
In step (1), raw material volume accounts for 2/3rds of water and raw material total volume;The decoction refers to being cooked by slow fire 40 ~60 minutes.
In step (2), adds water to water and just flood filter residue;The decoction refers to that high fire decocts 15-20 minutes.
In step (3), adds water to water and just flood raw material;The decoction refers to being cooked by slow fire 40-60 minutes.
The present invention also provides a kind of suitable for irritable cough and the Chinese materia medica preparation of acute and chronic pharyngitis, by will be described Chinese medicine composition add or be not added excipient substance to be prepared into oral preparation.
The oral preparation is tablet, capsule, pill, powder, granule.
Further, when the oral preparation is capsule, preparation method are as follows: Chinese medicine composition loading 0 is bright 2/3rds of No. 0 gelatin hollow capsule volume are filled in glue Capsules.
In the raw material of Chinese medicine composition and Chinese materia medica preparation provided by the invention, each Chinese medicine drug effect is as follows:
Peppermint: sweating and heat resolving, dispersing stagnated hepatoqi, relieving sore throat and acesodyne, antipruritic;
Rhizoma Atractylodis Macrocephalae: strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, miscarriage prevention, be used for spleen eating less, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, oedema, Spontaneous perspiration, threatened abortion;
Bulbus fritillariae cirrhosae: moistening lung for removing phlegm, dissipating bind disappear carbuncle, antibacterial, bulbus fritillariae cirrhosae alkaloid and bulbus fritillariae cirrhosae saponin I~No. III, have not With the phlegm-dispelling functions of degree, wherein stronger with alkaloid and saponin III effect;
Dried orange peel: strengthening the spleen and stomach, ventilating, lowering the adverse-rising QI and eliminating phlegm;
Radix Paeoniae Alba: nourishing blood for regulating menstruation, astringing YIN to stop sweating, the analgesic of soft liver, suppressing liver-YANG;
Fuling peel: Li Shui, reduce swelling, swollen general edema of harnessing the river;
Radix Ophiopogonis: nourishing Yin and promoting production of body fluid, moistening lung and clearing away the heart-fire, antiphlogistic antibacterial;
Asparagus fern: nourishing yin and clearing heat, moistening lung nourshing kidney;
Dendrobium nobile: it dredges clearind deficient heat, strengthen the spleen and stomach, strengthening muscles and bones;
Dark plum: alleviation vomiting, relieving diarrhea with astringents, cough-relieving are quenched the thirst;
Jujube: tonifying middle-Jiao and Qi, nourishing blood and tranquilization;
Radix Isatidis: clearing heat and detoxicating, antibacterial anti-inflammatory, cool blood detumescence;
Fritillaria thunbergii: clearing heat and eliminating phlegm, powder detoxifcation;
Old ramulus mori: fire of boning brings down a fever, clears liver, improving eyesight;
Rhizoma Chuanxiong: promoting blood circulation, promote breath and open depression, wind-expelling pain-stopping;
Catechu: promoting blood circulation and stopping pain, hygroscopic sore, clearing lung and eliminating phlegm;
Terminalia flesh: chronic cough aphonia, chronic diarrhea, protracted dysentery, rectal prolapse, hematochezia, metrorrhagia and metrostaxis, leukorrhagia, spermatorrhea, frequent micturition are controlled;
Chrysanthemum: hemostasis, heat-clearing, dampness removing, helps digestion, improving eyesight, tranquilizing the mind at anti-inflammatory;
Coltsfoot: moistening lung to lower qi, relieving cough and reducing sputum;
The sterculia seed: clearing lung-heat heat, throat, blood pressure lowering;
Loguat leaf: clearing lung and eliminating phlegm, eliminating phlegm and relieving asthma, stopping nausea and vomiting by lowering the adverse flow of QI;
Wild chrysanthemum: relieve heat heat-clearing, calming the liver, improving eyesight, clearing away heat and toxic materials;
It is Rhododendron dauricum: warming lung and reducing phlegm, relieving cough and asthma, antihypertensive diuretic;
Honeysuckle: clearing heat and detoxicating, dispelling wind and heat from the body removes heat from the blood and relieve diarrhea;
Campanulaceae: cough-relieving apophlegmatic, treatment are cried out, treat pulmonary abscess;
Creeping dichondra herb: heat-clearing, dampness removing, removing toxic substances;
Fructus Forsythiae: clearing heat and detoxicating, dispersing swelling and dissipating binds, anti-inflammatory;
Mulberry leaf: dispelling wind and heat from the body, clearing away the lungheat and moisturizing, calming the liver and improving eyesight, cooling blood and hemostasis;
Purple perilla: relieving exterior syndrome and dispelling cold, relieving QI stagnancy in the stomach, regulating the flow of vital energy and preventing miscarriage, solving toxin of fish and crab;
Roxburgh anoectochilus terminal bud: clearing heat and cooling blood, evacuate pathogenic wind dampness removing, diuresis of reinforcing the kidney;
Dandelion: clearing heat and detoxicating, dispersing swelling and dissipating binds, inducing diuresis for treating strangurtia;
Fennel seeds: warming kidney for dispelling cold, cold-dispelling pain-relieving, regulating qi-flowing for harmonizing stomach;
Radix bupleuri: evacuation brings down a fever, stops malaria, soothing liver-qi stagnation;
Cortex cinnamomi: sedation and analgesia, cooling, antibacterial, promoting menstruation;
Radix Glycyrrhizae: clearing heat and detoxicating, expelling phlegm and arresting coughing, anti-curing oncoma;
Gorgon fruit: reinforcing the kidney and controlling noctural emission, tonifying spleen stopping leak;
Caulis bambusae in taenian: clearing heat and eliminating phlegm relieves restlessness and prevents vomiting, miscarriage prevention cool blood;
Glutinous rehmannia: heart tonifying diuresis, antipyretic anti-inflammatory promote blood clotting and reduce the effect of blood glucose;
Corydlis bungeana: clearing heat and detoxicating, control that warm disease high fever is irritated, influenza;
Herba Andrographitis: heat clearing and inflammation relieving, antibacterial, Hepatoprotective cholagogue;
The fleece-flower root: turbid wet down is changed in nourishing liver and kidney, benefiting essence-blood, black beard and hair, strengthening the bones and muscles;
Bryozoatum: clearing lung-heat fire changes old phlegm, and softening hard masses are treating stranguria, controls phlegm heat panting and coughs, old phlegm block, goiter, scrofula, stranguria syndrome, hernia Gas, sore swells, mesh screen;
Radix Astragali: tonifying Qi, hidroschesis, inducing diuresis to remove edema, apocenosis;
Concha meretricis seu cylinae: hyperacidity and pain relief, clearing lung and eliminating phlegm, inducing diuresis for removing edema, resolving hard lump.
In above-mentioned kinds of traditional Chinese medicines, bryozoatum is shared with two medicine of Radix Astragali, clearing heat-fire, and preventing phlegm from forming and stopping coughing asthma is used for convulsive seizure due to phlegm-fire gas The cough effect closed is good.Dried orange peel and Radix Glycyrrhizae are with using invigorating the lung and benefiting vital QI, with Poria cocos with then playing the role of clearing damp, stop up on treatment sputum, with The same hot phlegm of removing of caulis bambusae in taenian.Asparagus fern, Radix Ophiopogonis, Radix Isatidis, campanulaceae and Radix Glycyrrhizae reducing pharyngeal swelling.Dendrobium nobile and honeysuckle share heat-clearing and support Yin.
Same use of coltsfoot, Radix Paeoniae Alba, Radix Glycyrrhizae, jujube is solely coughed in gas in consumptive lung disease.Chrysanthemum compatibility honeysuckle, campanulaceae evacuate heat-clearing, Removing toxicity for eliminating carbuncles, the efficacy of a drug guide drugs to illness station, resolving phlegm and relieving cough, swallow sharp sound and open.Coltsfoot, two medicine phase Wu Yingyong of purple perilla, the function of preventing phlegm from forming and stopping coughing are big Increase, and energy middle benefit gas drop is inverse, qi-regulating then helps phlegm, and then cough and asthma is fixed for sending down abnormally ascending.
Radix Ophiopogonis, mulberry leaf, Radix Astragali, campanulaceae compatibility, wind-heat dissipating, clearing heat and nourishing yin, moistening lung to arrest cough.Both bryozoatum and concha meretricis seu cylinae It refers and synthesizes, brings out the best in each other, clearing lung-heat heat lets out irascibility, changes old phlegm, goes chronic phlegm, cough-relieving, and hemostasis function enhancing is used for liver lung phlegm-heat cough, phlegm More, hemoptysis person's effect is good.
The sterculia seed, bulbus fritillariae cirrhosae, honeysuckle, campanulaceae compatible use have moistening lung, expectoration, cough-relieving, heat-clearing, removing toxic substances, can be relieved Improve the symptoms such as cough, abundant expectoration, foreign body sensation caused by chronic pharyngitis;Loguat leaf Compatibility with Radix Astragali, mulberry leaf, radix bupleuri, Radix Ophiopogonis and tendril-leaved fritillary bulb Mother, clearing lung and eliminating phlegm cough-relieving, dispelling wind promoting the dispersing function of the lung.Wild chrysanthemum matches dandelion, honeysuckle and campanulaceae, reducing pharyngeal swelling.Fructus Forsythiae, honeysuckle, Pu The product of public English and wild chrysanthemum removing toxicity for detumescence control disease scrofula subcutaneous nodule with using.Mulberry leaf compatibility chrysanthemum, Fructus Forsythiae and fritillaria, it is sweet tremble with fear it is light, it is light clear Evacuation is longer than wind-heat dissipating, and energy clearing lung and relieving cough, cool moistening lung dryness.
Roxburgh anoectochilus terminal bud Compatibility with Radix Astragali enters kidney, the heart, lung three and passes through, can improve the immunity of the human body comprehensively, and enhancing human body supports disease Drag.Fennel seeds compatibility cortex cinnamomi, fennel seeds temperature liver kidney, warm uterus, promoting qi circulation and relieving pain;Cortex cinnamomi warming kidney and enhancing yang, eliminating cold to stop pain, two medicines close With there is the effect of warm lower member, eliminating cold to stop pain.Radix bupleuri compatibility Rhizoma Atractylodis Macrocephalae, radix bupleuri soothing liver-qi stagnation;Rhizoma Atractylodis Macrocephalae replenish qi to invigorate the spleen both 5 use, Soothing the liver tonifying spleen, the chest side of body that can treat stagnation of liver-QI with deficiency of the spleen has a pain, mental fatigue with loss of appetite person.
Caulis bambusae in taenian compatibility dendrobium nobile, caulis bambusae in taenian is sweet in flavor slightly cold, and gallbladder fire, stopping nausea and vomiting by lowering the adverse flow of QI are let out in clearing away the stomach-heat;Dendrobium nobile is sweet light cool in nature, nourishing stomach-YIN, Clearind deficient heat, cough-relieving of promoting the production of body fluid, the two 5 are used, and clearly, mend simultaneous the effect of applying, playing clearing heat and nourishing yin and middle tune stomach, stopping nausea and vomiting by lowering the adverse flow of QI altogether.Bulb of thunberg fritillary Mother, glutinous rehmannia, Fructus Forsythiae compatibility, clearing heat-fire, removing pattogenic heat from the blood and toxic material from the body.Scarlet fever is cured mainly, epidemic disease fire is golden, and body fluid is dry, and tongue is deep red thirsty, and mind is tired Larynx is rotten, and pulse condition string is big, acute diseases such as cholera and sunstroke point Yun Mizhe.
Rhizome of chuanxiong and the same expeling chill of wild chrysanthemum, peppermint.Terminalia flesh compatibility campanulaceae, Radix Glycyrrhizae three's compatible use, there is clearing lung-heat Relieving sore-throat opens the effect of sound, for treating aphonia caused by lung heat or with the person of having sore throat.Corydlis bungeana, wild chrysanthemum, dandelion and company It sticks up to share and controls furunculosis swelling and pain significant effect.Herba Andrographitis compatibility dried orange peel has good anti-inflammatory, protective effect to lung.Dandelion, Huang A kind of reed mentioned in ancient books, corydlis bungeana, Radix Isatidis share antiphlogistic antibacterial.
The above kinds of traditional Chinese medicines follows expelling wind and removing dampness, the clearing heat and detoxicating and invigorating qi and benefiting blood mutual compatible use of principle, the formula Containing there are many clearing heat and detoxicating, throat-benefiting drugs, and a variety of invigorating qi and benefiting bloods, mildness drug are added, overcome clearing heat and detoxicating, clear larynx Relieving sore-throat drug it is cold in nature, to overcome long-term use that can generate uncomfortable symptom to human body.This formula simultaneously more can the five internal organs in treatment The people having the same aspiration and interest, treating both manifestation and root cause of disease.This product is not simple pharmaceutical composition, is that inventor matches by the Chinese medicine that multiple clinical verification is drawn Square, mutual compatibility between each drug, scientific and precise is treatment irritable cough, the good merchantable brand of acute and chronic pharyngitis.
Compared with prior art, the invention has the following advantages that Traditional Chinese medicine composition formula provided by the invention all uses Pure plant Chinese herbal medicine develops, without any side effects without any Western medicine and hormone explosive component, and nonirritant, property is mild, More patients can be allowed acceptant.And effect is prominent, should not recur after healing.This product can be made into the oral system of diversified forms Agent product overcomes the disadvantages of traditional decoction mouthfeel is bad.
Specific embodiment
The following describes the present invention in detail with reference to examples.
Embodiment 1
It is a kind of suitable for irritable cough and the Chinese medicine composition of acute and chronic pharyngitis, the raw material including following parts by weight: 8 parts of peppermint, 4 parts of Rhizoma Atractylodis Macrocephalae, 5 parts of bulbus fritillariae cirrhosae, 4 parts of dried orange peel, 3 parts of Radix Paeoniae Alba, 5 parts of fuling peel, 5 parts of asparagus fern, 5 parts of dendrobium nobile, 4 parts of dark plum, 15 parts of jujube, 8 parts of Radix Isatidis, 4 parts of old ramulus mori, 4 parts of chrysanthemum, 6 parts of coltsfoot, Radix Ophiopogonis 10, part, 5 parts of bryozoatum, 8 parts of the sterculia seed, Pi It is 6 parts of rake leaf, 4 parts of wild chrysanthemum, Rhododendron dauricum 4 parts, 8 parts of honeysuckle, 7 parts of campanulaceae, 3 parts of creeping dichondra herb, 8 parts of Fructus Forsythiae, 3 parts of mulberry leaf, purple 6 parts of Soviet Union, 3 parts of roxburgh anoectochilus terminal bud, 4 parts of dandelion, 4 parts of fennel seeds, 10 parts of radix bupleuri, 3 parts of cortex cinnamomi, 10 parts of Radix Glycyrrhizae, 6 parts of Gorgon fruit, caulis bambusae in taenian 6 Part, 8 parts of fritillaria thunbergii, 6 parts of Rhizoma Chuanxiong, 3 parts of catechu, 2 parts of terminalia flesh, 6 parts of glutinous rehmannia, 5 parts of corydlis bungeana, 7 parts of Herba Andrographitis, 2 parts of Radix Astragali, what 12 parts of the tuber of multiflower knotweed, 10 parts of concha meretricis seu cylinae.
The Chinese medicine composition suitable for irritable cough and acute and chronic pharyngitis the preparation method comprises the following steps:
(1) by the peppermint of formula ratio, Rhizoma Atractylodis Macrocephalae, bulbus fritillariae cirrhosae, dried orange peel, Radix Paeoniae Alba, fuling peel, asparagus fern, Shi Kui, dark plum, Radix Isatidis, Old ramulus mori, chrysanthemum, coltsfoot, Radix Ophiopogonis, the sterculia seed, loguat leaf, wild chrysanthemum is Rhododendron dauricum, honeysuckle, campanulaceae, creeping dichondra herb, Fructus Forsythiae, Mulberry leaf, purple perilla, roxburgh anoectochilus terminal bud, dandelion, fennel seeds, radix bupleuri, cortex cinnamomi, Radix Glycyrrhizae, Gorgon fruit, caulis bambusae in taenian, fritillaria thunbergii, rhizome of chuanxiong, catechu, myrobalan Meat, glutinous rehmannia, corydlis bungeana, Herba Andrographitis, Radix Astragali mixing add water to be cooked by slow fire 40~60 minutes, and raw material volume accounts for water and raw material is overall Filtrate A and filter residue are collected in long-pending 2/3rds, filtering;
(2) filter residue adds water to water and just floods filter residue, and high fire decocts 15-20 minute, filtering, collection liquor B, by itself and filter Liquid A merges, and obtains liquor C;
(3) jujube of formula ratio is mixed with the fleece-flower root, adds water to water and just floods raw material, be cooked by slow fire 40-60 minutes, Gained filtrate merges with liquor C, obtains filtrate D;
(4) filtrate D be concentrated, be dry, pulverized, obtaining powder E;
(5) bryozoatum of formula ratio is crushed to partial size in 100 mesh hereinafter, mixing with powder E with concha meretricis seu cylinae, can be obtained The Chinese medicine composition.
The Chinese medicine composition that the present embodiment is obtained is fitted into No. 0 gelatin hollow capsule, and explosive payload is No. 0 hollow glue of gelatin Capsule maximum can receiving volume 2/3.
The instructions of taking of capsule are as follows: one after each meal, one time 5,3 times a day.
Points for attention: if (1) this product discovery is rotten forbids to take;
(2) breast feeding women, pregnant woman and children forbid taking;
(3) Patients with Cardiovascular/Cerebrovascular Diseases need to be taken with caution;
(4) renal insufficiency person forbids to take;
(5) deficiency-cold in spleen and stomach person cautiously takes;
(6) diabetic forbids to take.
Embodiment 2
It is a kind of suitable for irritable cough and the Chinese medicine composition of acute and chronic pharyngitis, the raw material including following parts by weight: 5 parts of peppermint, 6 parts of Rhizoma Atractylodis Macrocephalae, 3 parts of bulbus fritillariae cirrhosae, 3 parts of dried orange peel, 4 parts of Radix Paeoniae Alba, 6 parts of fuling peel, 4 parts of asparagus fern, 6 parts of dendrobium nobile, 5 parts of dark plum, 12 parts of jujube, 7 parts of Radix Isatidis, 3 parts of old ramulus mori, 5 parts of chrysanthemum, 4 parts of coltsfoot, 9 parts of Radix Ophiopogonis, 4 parts of bryozoatum, 9 parts of the sterculia seed, loquat 7 parts of leaf, 5 parts of wild chrysanthemum, Rhododendron dauricum 6 parts, 6 parts of honeysuckle, 5 parts of campanulaceae, 4 parts of creeping dichondra herb, 7 parts of Fructus Forsythiae, 5 parts of mulberry leaf, purple perilla 7 Part, 4 parts of roxburgh anoectochilus terminal bud, 6 parts of dandelion, 3 parts of fennel seeds, radix bupleuri 6,4 parts of cortex cinnamomi, 8 parts of Radix Glycyrrhizae, 4 parts of Gorgon fruit, 7 parts of caulis bambusae in taenian, fritillaria thunbergii 7 parts, 8 parts of Rhizoma Chuanxiong, 5 parts of catechu, 4 parts of terminalia flesh, 7 parts of glutinous rehmannia, 6 parts of corydlis bungeana, 6 parts of Herba Andrographitis, 4 parts of Radix Astragali, 10 parts of the fleece-flower root, 12 parts of concha meretricis seu cylinae.
The Chinese medicine composition suitable for irritable cough and acute and chronic pharyngitis the preparation method comprises the following steps:
(1) by the peppermint of formula ratio, Rhizoma Atractylodis Macrocephalae, bulbus fritillariae cirrhosae, dried orange peel, Radix Paeoniae Alba, fuling peel, asparagus fern, Shi Kui, dark plum, Radix Isatidis, Old ramulus mori, chrysanthemum, coltsfoot, Radix Ophiopogonis, the sterculia seed, loguat leaf, wild chrysanthemum is Rhododendron dauricum, honeysuckle, campanulaceae, creeping dichondra herb, Fructus Forsythiae, Mulberry leaf, purple perilla, roxburgh anoectochilus terminal bud, dandelion, fennel seeds, radix bupleuri, cortex cinnamomi, Radix Glycyrrhizae, Gorgon fruit, caulis bambusae in taenian, fritillaria thunbergii, rhizome of chuanxiong, catechu, myrobalan Meat, glutinous rehmannia, corydlis bungeana, Herba Andrographitis, Radix Astragali mixing add water to be cooked by slow fire 40~60 minutes, and raw material volume accounts for water and raw material is overall Filtrate A and filter residue are collected in long-pending 2/3rds, filtering;
(2) filter residue adds water to water and just floods filter residue, and high fire decocts 15-20 minute, filtering, collection liquor B, by itself and filter Liquid A merges, and obtains liquor C;
(3) jujube of formula ratio is mixed with the fleece-flower root, adds water to water and just floods raw material, be cooked by slow fire 40-60 minutes, Gained filtrate merges with liquor C, obtains filtrate D;
(4) filtrate D be concentrated, be dry, pulverized, obtaining powder E;
(5) bryozoatum of formula ratio is crushed to partial size in 100 mesh hereinafter, mixing with powder E with concha meretricis seu cylinae, can be obtained The Chinese medicine composition.
The Chinese medicine composition that the present embodiment is obtained is fitted into No. 0 gelatin hollow capsule, and explosive payload is No. 0 hollow glue of gelatin Capsule maximum can receiving volume 2/3, Chinese medicinal capsule preparation is made.
The instructions of taking of Chinese medicinal capsule preparation are as follows: one after each meal, one time 5,3 times a day.
Points for attention: if (1) this product discovery is rotten forbids to take;
(2) breast feeding women, pregnant woman and children forbid taking;
(3) Patients with Cardiovascular/Cerebrovascular Diseases need to be taken with caution;
(4) renal insufficiency person forbids to take;
(5) deficiency-cold in spleen and stomach person cautiously takes;
(6) diabetic forbids to take.
The obtained Chinese medicinal capsule preparation for being suitable for irritable cough and acute and chronic pharyngitis of the above embodiment of the present invention Clinical effectiveness it is as follows:
Case 1:*** pharyngitis patient, throat is 1 year uncomfortable, and nausea, vomiting, using this product January, symptom takes an evident turn for the better, Continuing to take half a month is almost recovered, and patient is not recurred half a year, and autumn and winter season is during which passed through;
Case 2:*** irritable cough, pharyngitis patient, repeated coughing's half a year, pharyngitis were broken out close to half a year, and this product is used Two weeks takes an evident turn for the better phenomenon, is almost recovered within 1 month, does not recur in half a year;
Case 3:*** patients with chronic pharyngitis, morning get up to brush teeth nausea, and cough with repeatability, and obstinate is taken This product two weeks symptom turns for the better by and large, and continues to take two weeks after treatment, pharyngeal clarity, half a year does not recur;
Case 4:*** patient, long-term to smoke, cough does not stop, and takes this product nearly one month, existing because working principle stops The symptoms were significantly improved;
Case 5;* * acpuei pharyngitis patient coughs always after western medical treatment, takes this product one week, pharyngeal burn feeling disappears It loses, continues to take two weeks, cough symptom disappears, and does not recur at present;
Case 6:*** patient is regular to drink, pharyngeal shouting pain, and interruption takes this product and adds up one and a half months, does not drink now Under wine state, pharyngeal no significant discomfort, tingling sensation disappears;
Case 7:*** patient, chemical plant employee suck irritative gas for a long time, and dry cough is more than, take this product two Month, next year continues to take one month and consolidate, and cough symptom disappears at present;
Case 8:*** patient, sanitationman, frequent getting up early are had a cold for a long time, throat abundant expectoration, and western medical treatment effect is unknown It is aobvious, take this product one month, throat clarity, malaise symptoms mitigate;
Case 9:*** patient likes fishing, and often has a cold in waterside, and throat swells and ache for a long time, takes this product one month, Sense of discomfort disappears, and stops fishing later, not recur in half a year;
Case 10:*** patient throat is uncomfortable, and throat inflammation always takes this product nearly one month, and throat sense of discomfort is obvious Mitigate, throat inflammation phenomenon disappears, and follow-up at present does not have recurrence appearance.
The Chinese medicine composition provided by the present invention for being suitable for irritable cough and acute and chronic pharyngitis, can also add or be not added Excipient substance is prepared into tablet, pill, powder, granule dosage form.
It is above-mentioned referring to embodiment to a kind of suitable for irritable cough and the Chinese medicine composition and Chinese medicine of acute and chronic pharyngitis The detailed description that preparation carries out, is illustrative without being restrictive, can enumerate several implementations according to limited range Example, therefore the change and modification in the case where not departing from present general inventive concept, should belong within protection scope of the present invention.

Claims (10)

1. a kind of suitable for irritable cough and the Chinese medicine composition of acute and chronic pharyngitis, which is characterized in that including following weight The raw material of part: 5-8 parts of peppermint, 3-6 parts of Rhizoma Atractylodis Macrocephalae, 3-5 parts of bulbus fritillariae cirrhosae, 2-4 parts of dried orange peel, 3-5 parts of Radix Paeoniae Alba, 4-6 parts of fuling peel, asparagus fern 3-5 parts, 5-7 parts of dendrobium nobile, 3-5 parts of dark plum, 10-15 parts of jujube, 5-8 parts of Radix Isatidis, old ramulus mori 3-4 parts, 4-6 parts of chrysanthemum, coltsfoot 3-6 parts, Radix Ophiopogonis 8-10 part, 3-5 parts of bryozoatum, 8-10 parts of the sterculia seed, 5-7 parts of loguat leaf, 4-6 parts of wild chrysanthemum, Rhododendron dauricum 4-7 Part, 5-8 parts of honeysuckle, 4-7 parts of campanulaceae, 2-5 parts of creeping dichondra herb, 5-8 parts of Fructus Forsythiae, 3-6 parts of mulberry leaf, 5-8 parts of purple perilla, roxburgh anoectochilus terminal bud 3- 6 parts, 4-7 parts of dandelion, 2-4 parts of fennel seeds, 6-10 parts of radix bupleuri, 3-5 parts of cortex cinnamomi, 6-10 parts of Radix Glycyrrhizae, 4-6 parts of Gorgon fruit, caulis bambusae in taenian 6-8 Part, 5-8 parts of fritillaria thunbergii, 6-10 parts of Rhizoma Chuanxiong, 3-7 parts of catechu, 2-5 parts of terminalia flesh, 6-8 parts of glutinous rehmannia, 5-7 parts of corydlis bungeana, Herba Andrographitis 5-7 parts, 2-5 parts of Radix Astragali, 10-12 parts of the fleece-flower root, 9-13 parts of concha meretricis seu cylinae
2. according to claim 1 exist suitable for irritable cough and the Chinese medicine composition of acute and chronic pharyngitis, feature In the raw material including following parts by weight: 8 parts of peppermint, 4 parts of Rhizoma Atractylodis Macrocephalae, 5 parts of bulbus fritillariae cirrhosae, 4 parts of dried orange peel, 3 parts of Radix Paeoniae Alba, 5 parts of fuling peel, 5 parts of asparagus fern, 5 parts of dendrobium nobile, 4 parts of dark plum, 15 parts of jujube, 8 parts of Radix Isatidis, 4 parts of old ramulus mori, 4 parts of chrysanthemum, 6 parts of coltsfoot, Radix Ophiopogonis 10 Part, 5 parts of bryozoatum, 8 parts of the sterculia seed, 6 parts of loguat leaf, 4 parts of wild chrysanthemum, Rhododendron dauricum 4 parts, 8 parts of honeysuckle, 7 parts of campanulaceae, small money 3 parts of grass, 8 parts of Fructus Forsythiae, 3 parts of mulberry leaf, 6 parts of purple perilla, 3 parts of roxburgh anoectochilus terminal bud, 4 parts of dandelion, 4 parts of fennel seeds, 10 parts of radix bupleuri, 3 parts of cortex cinnamomi, 10 parts of Radix Glycyrrhizae, 6 parts of Gorgon fruit, 6 parts of caulis bambusae in taenian, 8 parts of fritillaria thunbergii, 6 parts of Rhizoma Chuanxiong, 3 parts of catechu, 2 parts of terminalia flesh, 6 parts of glutinous rehmannia, corydlis bungeana 5 Part, 7 parts of Herba Andrographitis, 2 parts of Radix Astragali, 12 parts of the fleece-flower root, 10 parts of concha meretricis seu cylinae.
3. according to claim 1 exist suitable for irritable cough and the Chinese medicine composition of acute and chronic pharyngitis, feature In the raw material including following parts by weight: 5 parts of peppermint, 6 parts of Rhizoma Atractylodis Macrocephalae, 3 parts of bulbus fritillariae cirrhosae, 3 parts of dried orange peel, 4 parts of Radix Paeoniae Alba, 6 parts of fuling peel, 4 parts of asparagus fern, 6 parts of dendrobium nobile, 5 parts of dark plum, 12 parts of jujube, 7 parts of Radix Isatidis, 3 parts of old ramulus mori, 5 parts of chrysanthemum, 4 parts of coltsfoot, 9 parts of Radix Ophiopogonis, 4 parts of bryozoatum, 9 parts of the sterculia seed, 7 parts of loguat leaf, 5 parts of wild chrysanthemum, Rhododendron dauricum 6 parts, 6 parts of honeysuckle, 5 parts of campanulaceae, creeping dichondra herb 4 Part, 7 parts of Fructus Forsythiae, 5 parts of mulberry leaf, 7 parts of purple perilla, 4 parts of roxburgh anoectochilus terminal bud, 6 parts of dandelion, 3 parts of fennel seeds, radix bupleuri 6,4 parts of cortex cinnamomi, Radix Glycyrrhizae 8 Part, 4 parts of Gorgon fruit, 7 parts of caulis bambusae in taenian, 7 parts of fritillaria thunbergii, 8 parts of Rhizoma Chuanxiong, 5 parts of catechu, 4 parts of terminalia flesh, 7 parts of glutinous rehmannia, 6 parts of corydlis bungeana, punching 6 parts of lotus, 4 parts of Radix Astragali, 10 parts of the fleece-flower root, 12 parts of concha meretricis seu cylinae.
4. the Chinese medicine composition for being suitable for irritable cough and acute and chronic pharyngitis according to claim 1 to 3 Preparation method, which is characterized in that the preparation method comprises the following steps:
(1) by the peppermint of formula ratio, Rhizoma Atractylodis Macrocephalae, bulbus fritillariae cirrhosae, dried orange peel, Radix Paeoniae Alba, fuling peel, asparagus fern, Shi Kui, dark plum, Radix Isatidis, Lao Sang Branch, chrysanthemum, coltsfoot, Radix Ophiopogonis, the sterculia seed, loguat leaf, wild chrysanthemum is Rhododendron dauricum, honeysuckle, campanulaceae, creeping dichondra herb, Fructus Forsythiae, mulberry leaf, Purple perilla, roxburgh anoectochilus terminal bud, dandelion, fennel seeds, radix bupleuri, cortex cinnamomi, Radix Glycyrrhizae, Gorgon fruit, caulis bambusae in taenian, fritillaria thunbergii, rhizome of chuanxiong, catechu, terminalia flesh, ground Huang, corydlis bungeana, Herba Andrographitis, Radix Astragali mixing add water to cook, filter, collect filtrate A and filter residue;
(2) filter residue adds water to decoct repeatedly once, and filtering collects liquor B, it is merged with filtrate A, obtains liquor C;
(3) jujube of formula ratio is mixed with the fleece-flower root, is added water to cook, gained filtrate merges with liquor C, obtains filtrate D;
(4) filtrate D be concentrated, be dry, pulverized, obtaining powder E;
(5) it is mixed after crushing the bryozoatum of formula ratio with concha meretricis seu cylinae with powder E, the Chinese medicine composition can be obtained.
5. the preparation method according to claim 4, which is characterized in that in step (1), raw material volume accounts for water and raw material is overall Long-pending 2/3rds;The decoction refers to being cooked by slow fire 40~60 minutes.
6. the preparation method according to claim 4, which is characterized in that in step (2), add water to water and just flood filter residue; The decoction refers to that high fire decocts 15-20 minutes.
7. the preparation method according to claim 4, which is characterized in that in step (3), add water to water and just flood raw material; The decoction refers to being cooked by slow fire 40-60 minutes.
8. a kind of suitable for irritable cough and the Chinese materia medica preparation of acute and chronic pharyngitis, which is characterized in that by by claim Chinese medicine composition described in 1-3 any one adds or is not added excipient substance to be prepared into oral preparation.
9. the Chinese materia medica preparation according to claim 8 for being suitable for irritable cough and acute and chronic pharyngitis, which is characterized in that The oral preparation is tablet, capsule, pill, powder, granule.
10. according to claim 8 exist suitable for irritable cough and the Chinese materia medica preparation of acute and chronic pharyngitis, feature When, the oral preparation is capsule, preparation method are as follows: the Chinese medicine composition is fitted into gelatin hollow capsule be filled to it is bright 2/3rds of glue Capsules volume.
CN201910075702.9A 2019-01-25 2019-01-25 It is a kind of suitable for irritable cough and the Chinese medicine composition and Chinese materia medica preparation of acute and chronic pharyngitis Pending CN109646592A (en)

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