CN109620220A - A kind of EEG and EIT signal synchronous collection device - Google Patents
A kind of EEG and EIT signal synchronous collection device Download PDFInfo
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- CN109620220A CN109620220A CN201910132384.5A CN201910132384A CN109620220A CN 109620220 A CN109620220 A CN 109620220A CN 201910132384 A CN201910132384 A CN 201910132384A CN 109620220 A CN109620220 A CN 109620220A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/369—Electroencephalography [EEG]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
- A61B5/0536—Impedance imaging, e.g. by tomography
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Abstract
The invention discloses a kind of EEG and EIT signal synchronous collection devices, comprising: the EIT current generating circuit of brain is acted on for generating EIT electric current;The frequency changer circuit that frequency conversion exports respectively is extracted to brain EIT signal and EEG signal;Frequency changer circuit EIT signal output end is connected to measure the EIT measuring circuit of brain different location impedance;Frequency changer circuit EEG signal output end is connected to obtain the signal acquisition circuit of EEG signals.Head part is transmitted to using the safety circuit that EIT current generating circuit generates, acquire the EIT signal and EEG signal of brain simultaneously using frequency changer circuit, and output is divided to EIT measuring circuit and signal acquisition circuit, overcome the limitation of EEG and EIT separation system, EEG signal and EIT signal can be obtained simultaneously, and can be with the contact impedance of real-time detection electrode and skin.
Description
Technical field
The present invention relates to physiology signal acquisition device fields, and in particular to a kind of EEG and EIT signal synchronous collection dress
It sets.
Background technique
Presently, there are brain wave acquisition equipment in, generally existing two problems, a kind of equipment has spatial resolution high, but
It is the low feature of temporal resolution, such as fMRI (Functional Magnetic Resonance Imaging) and PET
(Positron EmissionTomography) etc.;There are time high resolutions for another kind of equipment, but spatial resolution is low
Feature, such as most of EEG acquire equipment.Therefore research and development can be realized temporal resolution it is high, again being capable of reality to the greatest extent
The existing high brain wave acquisition equipment of spatial resolution is a main trend and is a great problem.To solve the above-mentioned problems, it is generally the case that
Collector uses two kinds of equipment, and the spatial information of head part is obtained by the high equipment acquisition of spatial resolution, is led to again later
The equipment for crossing time high resolution realizes that the real-time monitoring of EEG signals, the method are most common during eeg signal acquisition
Method.This acquisition method has certain problems, and on the one hand this acquisition method can not preferably realize EEG to a certain extent
The synchronous acquisition of signal and EIT signal.Since human metabolism can make tissue change, equipment acquisition is different
Step, this will cause the generation position that abnormal EEG signals can not be accurately positioned, the positioning device volume on the other hand used greatly and
At high cost, which limits this equipment to use in hospital or scientific research.
Summary of the invention
In order to solve the above-mentioned technical problem the present invention provides a kind of EEG and EIT signal synchronous collection device.
The present invention is achieved through the following technical solutions:
A kind of EEG and EIT signal synchronous collection device, comprising:
The EIT current generating circuit of brain is acted on for generating EIT electric current;
The frequency changer circuit that frequency conversion exports respectively is extracted to brain EIT signal and EEG signal;
Frequency changer circuit EIT signal output end is connected to measure the EIT measuring circuit of brain different location impedance;
Frequency changer circuit EEG signal output end is connected to obtain the signal acquisition circuit of EEG signals.
EEG, that is, brain wave, EIT, that is, electrical impedance imaging.This programme is passed using the safety circuit that EIT current generating circuit generates
Head part is transported to, acquires the EIT signal and EEG signal of brain simultaneously using frequency changer circuit, and divide output to EIT measuring circuit
And signal acquisition circuit, realize the real-time detection of skin and electrode contact impedance.Using the present apparatus, EEG and EIT separation is overcome
The limitation of system can obtain EEG signal and EIT signal simultaneously, and can be with the contact impedance of real-time detection electrode and skin.
The circuit measures the conductive information for obtaining human body head tissue by EIT, the accuracy of the source positioning of EEG is promoted, when to make
Between high resolution and the high brain electric equipment of spatial resolution provide preferable hardware condition.The small in size and cost of this equipment
It is low, it can be in multi-field popularization and use.
Preferably, the EIT current generating circuit includes sequentially connected EIT electric current generation module, security protection electricity
Road.Safety protection circuit is set between EIT electric current generation module and human brain, avoids electric current is excessive from causing to endanger to human body
Evil improves safety in utilization.
Further, the EIT circuit evolving module include digital analog converter, by D/A converting circuit output be converted to electricity
Flow the constant-current source circuit of signal and the controller for controlling digital analog converter output frequency information.
Further, the safety protection circuit is photoelectric isolating circuit.It is special using the electrical isolation of photoelectric isolating circuit
Property, it avoids EIT electric current from generating source and direct body contact, plays the role of protecting human body.
Preferably, the frequency changer circuit includes the first frequency conversion branch and the second frequency conversion branch, the first frequency conversion branch
Including sequentially connected low-pass filter, the first frequency converter, the first bandpass filter;The second frequency conversion branch includes successively connecting
The second bandpass filter, the second frequency converter, the third bandpass filter connect.
Compared with prior art, the present invention having the following advantages and benefits:
1, the present invention is transmitted to head part using the safety circuit that EIT current generating circuit generates, and is adopted simultaneously using frequency changer circuit
Collect the EIT signal and EEG signal of brain, and divide output to EIT measuring circuit and signal acquisition circuit, overcomes EEG and EIT
The limitation of separation system, can obtain EEG signal and EIT signal simultaneously, and can contact with real-time detection electrode with skin
Impedance.
2, the present invention obtains the conductive information of human body head tissue by the measurement of EIT current generating circuit, promotes the source of EEG
The accuracy of positioning provides preferable hardware condition for Production Time high resolution and the high brain electric equipment of spatial resolution.
Detailed description of the invention
Attached drawing described herein is used to provide to further understand the embodiment of the present invention, constitutes one of the application
Point, do not constitute the restriction to the embodiment of the present invention.
Fig. 1 is the principle of the present invention block diagram.
Fig. 2 is the schematic diagram of EIT current generating circuit.
Fig. 3 is the schematic diagram of frequency changer circuit.
Specific embodiment
To make the objectives, technical solutions, and advantages of the present invention clearer, below with reference to embodiment and attached drawing, to this
Invention is described in further detail, and exemplary embodiment of the invention and its explanation for explaining only the invention, are not made
For limitation of the invention.
Embodiment 1
A kind of EEG and EIT signal synchronous collection device as shown in Figure 1, including EIT current generating circuit, frequency changer circuit, EIT
Measuring circuit, signal acquisition circuit.EIT current generating circuit generation EIT electric current and effect and human brain, while frequency changer circuit is to big
Brain EIT signal and EEG signal extract frequency conversion and and export respectively, EIT measuring circuit, signal acquisition circuit are connected to
On the EIT signal output end of frequency changer circuit, EEG signal output end, signal acquisition circuit obtains EEG signals, EIT measuring circuit
According to EIT signal measurement brain different location impedance.
The present apparatus is transmitted to head part based on the safety circuit that EIT current generating circuit generates, simultaneously using frequency changer circuit
Acquire the EIT signal and EEG signal of brain, and divide output to EIT measuring circuit and signal acquisition circuit, overcome EEG and
The limitation of EIT separation system, can obtain EEG signal and EIT signal simultaneously, and can connecing with real-time detection electrode and skin
Touch impedance.The addition of frequency changer circuit realizes the synchronous acquisition of EEG signal and EIT signal, breaks traditional equipment and acquire brain at times
The shortcomings that electric signal and EIT signal, the method in the invention can detect brain electricity all the period of time, useful signal avoided to lose.
Embodiment 2
The present embodiment refines EIT current generating circuit on the basis of above-described embodiment principle, such as Fig. 1 and Fig. 2 institute
Show.EIT current generating circuit includes sequentially connected EIT electric current generation module, safety protection circuit.EIT circuit evolving module
Including digital analog converter, D/A converting circuit output is converted into the constant-current source circuit of current signal and is used to control digital-to-analogue conversion
The controller of device output frequency information.DAC8760 can be used in digital analog converter, and controller controls its voltage for exporting different frequency
Signal, operational amplifier A1, resistance R1, resistance R2, triode T1, operational amplifier A2, resistance R3, triode T2 constitute constant current
The voltage value that digital analog converter exports is converted to current source by source circuit.Safety protection circuit is photoelectric isolating circuit, is realized defeated
Enter the physical isolation with output, convert electrical signals to optical signal, then by converting again, switchs to electric signal output, at present
It is that power outputting section is isolated with human body junction, plays the role of protecting human body.Entire EIT circuit evolving module is in controller
Control under generate amplitude be 60 μ A, the sine wave that frequency is 100KHz and duty ratio is 50%, flowed through by safety protection circuit
One electrode is transferred to the head of people.
Embodiment 3
The present embodiment refines frequency changer circuit on the basis of above-described embodiment principle, as shown in figures 1 and 3.Variable-frequency electric
Road includes the first frequency conversion branch and the second frequency conversion branch, while EIT current generating circuit effect on human body, is adopted using another electrode
Collection human body signal and the electrode signal enter two branches simultaneously, and two branches respectively carry out brain EIT signal and EEG signal
Extract frequency conversion output.
First frequency conversion branch includes sequentially connected low-pass filter, the first frequency converter, the first bandpass filter, works as electrode
After signal enters the branch, low-pass filter extracts 100Hz or less EEG signals and carries out through the first frequency converter such as GC5016
Frequency conversion is converted to 2kHz, by the first bandpass filter filtering clutter, obtains pure 2kHz and exports to signal acquisition circuit.
Second frequency conversion branch includes sequentially connected second bandpass filter, the second frequency converter, third bandpass filter.When
After electrode signal enters the branch, the EIT signal of 100Khz is obtained by the second bandpass filter, such as through the second frequency converter
GC5016 carries out down coversion, is converted to 1kHz, by third bandpass filter filtering clutter, obtain pure 1kHz export to
EIT measuring circuit.
EIT signal and EEG signal are divided using frequency changer circuit, both avoids interfering with each other, also drops high frequency E IT signal
Frequently, it reduces sample rate and reduces memory requirement, realize signal synchronous collection.
Above-described specific embodiment has carried out further the purpose of the present invention, technical scheme and beneficial effects
It is described in detail, it should be understood that being not intended to limit the present invention the foregoing is merely a specific embodiment of the invention
Protection scope, all within the spirits and principles of the present invention, any modification, equivalent substitution, improvement and etc. done should all include
Within protection scope of the present invention.
Claims (5)
1. a kind of EEG and EIT signal synchronous collection device characterized by comprising
The EIT current generating circuit of brain is acted on for generating EIT electric current;
The frequency changer circuit that frequency conversion exports respectively is extracted to brain EIT signal and EEG signal;
Frequency changer circuit EIT signal output end is connected to measure the EIT measuring circuit of brain different location impedance;
Frequency changer circuit EEG signal output end is connected to obtain the signal acquisition circuit of EEG signals.
2. a kind of EEG and EIT signal synchronous collection device according to claim 1, which is characterized in that the EIT electric current
Generative circuit includes sequentially connected EIT electric current generation module, safety protection circuit.
3. a kind of EEG and EIT signal synchronous collection device according to claim 2, which is characterized in that the EIT circuit
Generation module includes digital analog converter, D/A converting circuit output is converted to the constant-current source circuit of current signal and is used to control
The controller of digital analog converter output frequency information.
4. a kind of EEG and EIT signal synchronous collection device according to claim 2, which is characterized in that the security protection
Circuit is photoelectric isolating circuit.
5. a kind of EEG and EIT signal synchronous collection device according to claim 1, which is characterized in that the frequency changer circuit
Including the first frequency conversion branch and the second frequency conversion branch, the first frequency conversion branch includes sequentially connected low-pass filter, first
Frequency converter, the first bandpass filter;The second frequency conversion branch includes sequentially connected second bandpass filter, the second frequency conversion
Device, third bandpass filter.
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Cited By (1)
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CN112200912A (en) * | 2020-09-22 | 2021-01-08 | 深圳市丰盛生物科技有限公司 | Brain imaging system and method based on electrical impedance imaging and electroencephalogram signals |
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CN101199418A (en) * | 2006-12-12 | 2008-06-18 | 深圳迈瑞生物医疗电子股份有限公司 | Brain impedance detection circuitry and EEG checking device |
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