CN109602653A - Composition, cosmetics, Essence with white-skinned face function and preparation method thereof - Google Patents

Composition, cosmetics, Essence with white-skinned face function and preparation method thereof Download PDF

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CN109602653A
CN109602653A CN201811542372.1A CN201811542372A CN109602653A CN 109602653 A CN109602653 A CN 109602653A CN 201811542372 A CN201811542372 A CN 201811542372A CN 109602653 A CN109602653 A CN 109602653A
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white
essence
face function
skinned face
composition
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CN109602653B (en
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陈昭武
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Guangzhou Baiyun District Yanmei Cosmetics Factory
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Guangzhou Baiyun District Yanmei Cosmetics Factory
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/75Anti-irritant

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Abstract

The present invention relates to a kind of composition with white-skinned face function, cosmetics, Essence and preparation method thereof, the composition with white-skinned face function includes that the component of following mass parts is prepared: 0.3-5 parts of dendrobium candidum stem extraction, 0.1-4 parts of Angelica roots, 0.1-4 parts of Radix Notoginseng root extract and 0.1-4 parts of Astragalus membranacus root extract.Each component cooperates in the above-mentioned composition with white-skinned face function, by controlling the reasonable volume of each component, while so that each component is given full play to respective effect, also has the function of synergy.The above-mentioned composition with white-skinned face function not only has good whitening effect, also has effects that moisturizing, antiallergic are releived.

Description

Composition, cosmetics, Essence with white-skinned face function and preparation method thereof
Technical field
The present invention relates to cosmetic fields, more particularly to a kind of composition with white-skinned face function, cosmetics, Essence And preparation method thereof.
Background technique
With the continuous improvement of people's living standards, having effects that the market demand of the cosmetics of whitening and skin-protecting persistently increases It is long.But traditional skin-lightening cosmetic contains chemically synthesized whitening material mostly, to human body side effect while whitening Greatly, the commercially available skin-lightening cosmetic whitening effect containing natural extract is bad.
Summary of the invention
Based on this, it is necessary to which the bad problem of the whitening effect of the skin-lightening cosmetic for tradition containing natural extract mentions For a kind of good composition with white-skinned face function of whitening effect, cosmetics, Essence and preparation method thereof.
A kind of composition with white-skinned face function, the component including following mass parts are prepared:
Each component cooperates in the above-mentioned composition with white-skinned face function, by controlling the reasonable volume of each component, makes While each component gives full play to respective effect, also has the function of synergy.The above-mentioned composition with white-skinned face function is not But there is good whitening effect, also have effects that moisturizing, antiallergic are releived.
In one of the embodiments, the component of the composition with white-skinned face function further include glossy privet fruit extract, At least one of licorice root extract, daisy flower extract, Rosa centifolia flower extract and Jasminum officinale Linn extract.
In one of the embodiments, include the raw material components of following mass parts:
In one of the embodiments, include the raw material components of following mass parts:
The present invention also provides a kind of cosmetics.
A kind of cosmetics, including the composition of the present invention with white-skinned face function.
The present invention also provides a kind of Essences.
A kind of Essence, including the composition of the present invention with white-skinned face function, 1.3-15.5 parts of moisturizer and 75- 80 parts of water.
The Essence further includes preservative in one of the embodiments,.
The moisturizer is selected from acetylation Sodium Hyaluronate, polyglutamic acid and 1.3- the third two in one of the embodiments, At least one of alcohol.
Above-mentioned Essence not only has good whitening effect, also has effects that moisturizing, antiallergic are releived.
A kind of preparation method of Essence, the preparation method of the Essence include the following steps: in parts by mass,
1.3-15.5 parts of moisturizer and 75-80 parts of water are mixed, A phase is obtained;
Composition of the present invention with white-skinned face function is added in A phase and is uniformly mixed so as to obtain B phase;
Retain filtrate after the B phase is filtered to get Essence.
The preparation method of above-mentioned Essence is simple, and the Essence being prepared not only has good whitening effect, also has There is the effect of moisturizing, antiallergic are releived.
Specific embodiment
In order to make the foregoing objectives, features and advantages of the present invention clearer and more comprehensible, below to specific reality of the invention The mode of applying is described in detail.In the following description, numerous specific details are set forth in order to facilitate a full understanding of the present invention.But The invention can be embodied in many other ways as described herein, and those skilled in the art can be without prejudice to this hair Similar improvement is done in the case where bright intension, therefore the present invention is not limited by the specific embodiments disclosed below.
Unless otherwise defined, all technical and scientific terms used herein and belong to technical field of the invention The normally understood meaning of technical staff is identical.Term as used herein in the specification of the present invention is intended merely to description tool The purpose of the embodiment of body, it is not intended that in the limitation present invention.Term " and or " used herein includes one or more phases Any and all combinations of the listed item of pass.
A kind of composition with white-skinned face function is provided in one embodiment of the invention comprising the component of following mass parts It is prepared:
The key substance for influencing whitening skin is melanin, and for melanin in forming process, tyrosinase plays crucial work With, the generation of melanin number with tyrosinase have direct relationship.Therefore, the mechanism of skin-whitening mainly passes through inhibition Tyrosinase activity, to block the oxidative pathway of tyrosine generation melanin, the generation for reducing melanin reaches skin whitening Effect.
Wherein, Radix Angelicae Sinensis has the effects that anti-inflammatory, scavenging activated oxygen, enhancing immune function.Research has shown that angelica root mentions It takes object that can inhibit tyrosinase activity, so that tyrosine be blocked to generate the oxidative pathway of melanin, reduces the generation of melanin Achieve the effect that skin whitening.In addition, angelica extract also has effects that enhance skin epidermis water content, cell SOD activity.
Wherein, dendrobium candidum stem extraction can promote the AQP3 of cell aquaporin to express, and get through entire cross-film egg Bai Tongdao, conducive in the accessible cuticula into skin of nutriment in composition, in addition, dendrobium candidum stem extraction Also there is multiple pharmacological effect, such as enhance the immunocompetence of body, anti-oxidant, anti-aging, reduction blood glucose, fluid infusion promote the production of body fluid, invigorate blood circulation QI invigorating fundamentally adjusts function of human body, improves the sub-health state of human body, fundamentally improves skin brilliant white degree.In addition, iron Skin dendrobium nobile stem extraction is also rich in the nutriments such as polysaccharide, dendrobine, free amino acid, vitamin A, vitamin C, vitamin E, While extra-nutrition for skin, improves skin elasticity, moisturizing, increases skin to the resistance of extraneous poor environment.
Wherein, Radix Notoginseng root extract is also used as anti-inflammatory agent, the total soap of effective component Radix Notoginseng in addition to white-skinned face function Glycosides has stronger inhibiting effect to certain fungies, there is certain inhibiting effect to staphylococcus aureus, Escherichia coli, alleviates skin The various malaise symptoms of skin.
Wherein, Astragalus membranacus root extract, from the root of Astragalus membranacus, the important activity ingredient Radix Astragali soap that contains Glycosides can stimulate the proliferation of cortical cell, improve skin surface microenvironment.It is mutually flat with other components in the composition of white-skinned face function Weighing apparatus inhibits dendrobium candidum stem extraction jointly with Notogineng Extract, easily causes the Chinese medicine of skin allergy to have in Radix Notoginseng root extract Evil ingredient, promotes dendrobium candidum stem extraction, Radix Notoginseng root extract to the inhibiting effect of tyrosinase, is finally reached mild nourishing Purpose.
In one of the embodiments, the component of the composition with white-skinned face function further include glossy privet fruit extract and At least one of licorice root extract.Glossy privet fruit extract and licorice root extract can be further improved tool as auxiliary There is the whitening effect of the composition of white-skinned face function.
The component of the composition further includes daisy flower extract, Rosa centifolia flower extract in one of the embodiments, At least one of with Jasminum officinale Linn extract.Character temperature in daisy flower extract, Rosa centifolia flower extract and Jasminum officinale Linn extract With releive ingredient containing antiallergic, on the one hand can inhibit dendrobium candidum stem extraction, easily cause skin mistake in Radix Notoginseng root extract On the other hand quick Chinese medicine harmful components can also adjust skin microenvironment, be more conducive to that there is the component of white-skinned face function to enter skin It inside skin, inhibits tyrosinase activity, to avoid the formation of melanin, plays the purpose mildly nourished.
The composition with white-skinned face function includes that the component of following mass parts is prepared in one of the embodiments:
The composition with white-skinned face function includes that the component of following mass parts is prepared in one of the embodiments:
The composition with white-skinned face function includes that the component of following mass parts is prepared in one of the embodiments:
Wherein, Rosa centifolia flower extract, Jasminum officinale Linn extract, daisy flower extract, dendrobium candidum stem extraction, angelica root Extract, Radix Notoginseng root extract, Astragalus membranacus root extract, glossy privet fruit extract, licorice root extract can be purchased from city , each extract can also be respectively adopted following method extraction and be made, and each extract of the embodiment of the present invention is all made of down It states method to be made, specifically comprise the following steps:
1) high-quality fresh, good plant material is selected, after then being cleaned up with pure water, drying and dewatering is put into powder Raw material powder of the partial size less than 800 mesh is ground into broken machine.
2) raw material powder is transported in supercritical extraction reactor and carries out supercritical CO2Method extraction, then to supercritical extract CO is passed through in kettle2Gas, CO2Flow be 8kg/h, in the condition that extracting pressure is 20MPa-25MPa, extraction temperature is 35 DEG C Lower extraction 8h, obtains extract.
It 3) is 1:7g/L by extract addition pure water by solid-liquid ratio, heating distillation 5h, condensing reflux obtains extract.
Each component cooperates in the above-mentioned composition with white-skinned face function, by controlling the reasonable volume of each component, makes While each component gives full play to respective effect, also has the function of synergy.The above-mentioned composition with white-skinned face function is not But there is good whitening effect, also have effects that moisturizing, antiallergic are releived.
The present invention also provides a kind of cosmetics.
A kind of cosmetics comprising with the composition of white-skinned face function described in any embodiment of the present invention.
It is appreciated that the so-called cosmetics of the present invention can be a variety of productions such as toner, Essence, face cream, moisturizer Product no longer excessively repeat herein.
The present invention also provides a kind of Essences.
A kind of Essence comprising with composition, the 1.3-15.5 of white-skinned face function described in any embodiment of the present invention The moisturizer and 75-80 parts of water of part are prepared.
It is understood that the Essence in the present invention uniformly can be applied in facial mask substrate, it is fabricated to facial mask.
The Essence further includes preservative in one of the embodiments,.
The preservative can be the common preservative of cosmetic field, it is preferable that select food grade preservative sorbic acid At least one of potassium and sodium benzoate, food grade preservative is to human body Small side effects.Further, food grade preservative is selected The combination of potassium sorbate and sodium benzoate, potassium sorbate additional amount is 0.1-0.5 mass parts, sodium benzoate additional amount is 0.05- 0.4 mass parts.
The moisturizer is selected from acetylation Sodium Hyaluronate, polyglutamic acid and 1.3- the third two in one of the embodiments, At least one of alcohol.
The moisturizer is acetylation Sodium Hyaluronate, polyglutamic acid and 1.3- propylene glycol in one of the embodiments, The combination of three, it is preferable that in parts by mass, acetylation Sodium Hyaluronate is 0.01-0.2 parts, polyglutamic acid 0.01-0.3 Part, 1.3- propylene glycol are 1-15 parts.
Carboxyl and other polar groups in acetylation hyaluronic acid sodium molecule can form hydrogen bond, about 1g in conjunction with water Acetylation Sodium Hyaluronate can lock the water of 1000g.Preferably, the molecular weight of acetylation Sodium Hyaluronate be less than 30000Da or less is the acetylation Sodium Hyaluronate of extra small molecule in addition to having effects that potent water lock, moisturizing, also to ultraviolet light The Skin Cell of damage has significant repair ability, and molecular weight is lower, and repair ability is stronger.Meanwhile acetylation hyalomitome Sour sodium molecule also plays the role of pre- antiultraviolet sunburn.
Polyglutamic acid performance of keeping humidity is superior, can enhance skin elasticity, mildly inhibits tyrosine kinase activity, the safety of product Property and it is both effectiveness all have passed through comprehensively and have the certification of depth, safe source is edible raw material, and skin bullet is tested when long Property is greatly improved.
The plant moisturizing agent as made of sugar fermentation of 1.3- propylene glycol, the moment used can improve the angleplied laminate moisture of skin Amount.By being used in compounding with other moisturizer, the angleplied laminate amount of moisture for keeping being improved using moment can be continued, can be assigned after Give skin smooth, exquisiteness, moist use feeling.
Above-mentioned Essence not only has good whitening effect, also has effects that moisturizing, antiallergic are releived.
The present invention also provides a kind of preparation methods of Essence.
A kind of preparation method of Essence, the preparation method of the Essence include the following steps:
1.3-15.5 parts of moisturizer and 75-80 parts of water are mixed, A phase is obtained, then there is whitening function by of the present invention The composition of effect is added in A phase and is uniformly mixed so as to obtain B phase, then retains filtrate after the B phase is filtered to get Essence.
The preparation method of the Essence includes the following steps: in parts by mass in one of the embodiments, by acetyl It is mixed in agitated kettle with 78.5 parts of deionized water to change 0.05 part of Sodium Hyaluronate, 0.05 part of polyglutamic acid and 8 parts of 1.3- propylene glycol Merging stirs evenly, and obtains A phase, and then the composition by of the present invention with white-skinned face function is added in A phase and stirs evenly, In, mixing speed be 40 turns/min, stirring 60 minutes it is evenly dispersed to each component, obtain B phase, add 0.2 part of potassium sorbate, 0.2 part of sodium benzoate, continue to stir 50min, until preservative is dispersed in B phase, stops stirring, stand 30min, mistake Retain filtrate after the filtering of 500 mesh filter screens to get Essence.
The preparation method of above-mentioned Essence is simple, and the Essence being prepared not only has good whitening effect, also has There is the effect of moisturizing, antiallergic are releived.
In order to which objects and advantages of the present invention are more clearly understood, the present invention is carried out with reference to embodiments further It is described in detail.It should be appreciated that described herein, specific examples are only used to explain the present invention, is not intended to limit the present invention.
Embodiment 1
A kind of preparation method of Essence comprising following steps:
0.05 part of acetylation Sodium Hyaluronate and 8 parts of 1.3- propylene glycol are mixed in agitated kettle with 78.5 parts of deionized water And stir evenly, A phase is obtained, then each component of the composition into A phase in addition table 1 with white-skinned face function stirs evenly, Wherein, mixing speed is 40 turns/min, and stirring 60 minutes evenly dispersed to each component, obtains B phase, adds potassium sorbate 0.2 Part, 0.2 part of sodium benzoate continue to stir 50min, until preservative is dispersed in B phase, stop stirring, standing 30min, Retain filtrate after crossing the filtering of 500 mesh filter screens to get Essence.
Table 1
Material name Content (part)
Dendrobium candidum stem extraction 0.4
Angelica roots 0.1
Radix Notoginseng root extract 0.5
Astragalus membranacus root extract 0.2
Embodiment 2
A kind of preparation method of Essence comprising following steps:
0.05 part of acetylation Sodium Hyaluronate and 8 parts of 1.3- propylene glycol are mixed in agitated kettle with 78.5 parts of deionized water And stir evenly, A phase is obtained, then each component of the composition into A phase in addition table 2 with white-skinned face function stirs evenly, Wherein, mixing speed is 40 turns/min, and stirring 60 minutes evenly dispersed to each component, obtains B phase, adds potassium sorbate 0.2 Part, 0.2 part of sodium benzoate continue to stir 50min, until preservative is dispersed in B phase, stop stirring, standing 30min, Retain filtrate after crossing the filtering of 500 mesh filter screens to get Essence.
Table 2
Embodiment 3
A kind of preparation method of Essence comprising following steps:
By 8 parts of 0.05 part of acetylation Sodium Hyaluronate, 0.2 part of polyglutamic acid and 1.3- propylene glycol and deionized water 78.5 Part is mixed and stirred for uniformly, obtaining A phase in agitated kettle, and the composition in table 3 with white-skinned face function is then added into A phase Each component stirs evenly, wherein and mixing speed is 40 turns/min, and stirring 60 minutes are evenly dispersed to each component, obtains B phase, then 0.2 part of potassium sorbate, 0.2 part of sodium benzoate is added, continues to stir 50min, until preservative is dispersed in B phase, stops Stirring stands 30min, retains filtrate after crossing the filtering of 500 mesh filter screens to get Essence.
Table 3
Material name Content (part)
Dendrobium candidum stem extraction 4
Angelica roots 3
Radix Notoginseng root extract 3.5
Astragalus membranacus root extract 3.8
Glossy privet fruit extract 2.4
Licorice root extract 3
Embodiment 4
A kind of preparation method of Essence comprising following steps:
By 0.1 part of acetylation Sodium Hyaluronate, 0.25 part of polyglutamic acid and 8 parts and 78.5 parts of deionized water of 1.3- propylene glycol It is mixed and stirred for uniformly, obtaining A phase in agitated kettle, each of the composition in table 4 with white-skinned face function is then added into A phase Component stirs evenly, wherein and mixing speed is 40 turns/min, and stirring 60 minutes are evenly dispersed to each component, obtains B phase, then plus Enter 0.2 part of potassium sorbate, 0.2 part of sodium benzoate, continues to stir 50min, until preservative is dispersed in B phase, stop stirring It mixes, stands 30min, retain filtrate after crossing the filtering of 500 mesh filter screens to get Essence.
Table 4
Material name Content (part)
Dendrobium candidum stem extraction 4
Angelica roots 3
Radix Notoginseng root extract 3.5
Astragalus membranacus root extract 3.8
Glossy privet fruit extract 2.4
Licorice root extract 3
Daisy flower extract 1.4
Rosa centifolia flower extract 0.5
Jasminum officinale Linn extract 0.6
Comparative example 1
A kind of preparation method of Essence comprising following steps:
0.05 part of acetylation Sodium Hyaluronate and 8 parts of 1.3- propylene glycol are mixed in agitated kettle with 78.5 parts of deionized water And stir evenly, A phase is obtained, then each component of the composition into A phase in addition table 5 with white-skinned face function stirs evenly, Wherein, mixing speed is 40 turns/min, and stirring 60 minutes evenly dispersed to each component, obtains B phase, adds potassium sorbate 0.2 Part, 0.2 part of sodium benzoate continue to stir 50min, until preservative is dispersed in B phase, stop stirring, standing 30min, Retain filtrate after crossing the filtering of 500 mesh filter screens to get Essence.
Table 5
Material name Content (part)
Dendrobium candidum stem extraction 0.4
Angelica roots 0.1
Comparative example 2
A kind of preparation method of Essence comprising following steps:
0.05 part of acetylation Sodium Hyaluronate and 8 parts of 1.3- propylene glycol are mixed in agitated kettle with 78.5 parts of deionized water And stir evenly, A phase is obtained, then each component of the composition into A phase in addition table 6 with white-skinned face function stirs evenly, Wherein, mixing speed is 40 turns/min, and stirring 60 minutes evenly dispersed to each component, obtains B phase, adds potassium sorbate 0.2 Part, 0.2 part of sodium benzoate continue to stir 50min, until preservative is dispersed in B phase, stop stirring, standing 30min, Retain filtrate after crossing the filtering of 500 mesh filter screens to get Essence.
Table 6
Material name Content (part)
Dendrobium candidum stem extraction 0.4
Radix Notoginseng root extract 0.5
Astragalus membranacus root extract 0.2
Comparative example 3
A kind of preparation method of Essence comprising following steps:
0.05 part of acetylation Sodium Hyaluronate and 8 parts of 1.3- propylene glycol are mixed in agitated kettle with 78.5 parts of deionized water And stir evenly, A phase is obtained, then each component of the composition into A phase in addition table 7 with white-skinned face function stirs evenly, Wherein, mixing speed is 40 turns/min, and stirring 60 minutes evenly dispersed to each component, obtains B phase, adds potassium sorbate 0.2 Part, 0.2 part of sodium benzoate continue to stir 50min, until preservative is dispersed in B phase, stop stirring, standing 30min, Retain filtrate after crossing the filtering of 500 mesh filter screens to get Essence.
Table 7
Material name Content (part)
Angelica roots 0.1
Radix Notoginseng root extract 0.5
Astragalus membranacus root extract 0.2
Comparative example 4
A kind of preparation method of Essence comprising following steps:
0.05 part of acetylation Sodium Hyaluronate and 8 parts of 1.3- propylene glycol are mixed in agitated kettle with 78.5 parts of deionized water And stir evenly, A phase is obtained, then each component of the composition into A phase in addition table 8 with white-skinned face function stirs evenly, Wherein, mixing speed is 40 turns/min, and stirring 60 minutes evenly dispersed to each component, obtains B phase, adds potassium sorbate 0.2 Part, 0.2 part of sodium benzoate continue to stir 50min, until preservative is dispersed in B phase, stop stirring, standing 30min, Retain filtrate after crossing the filtering of 500 mesh filter screens to get Essence.
Table 8
Material name Content (part)
Angelica roots 7
Radix Notoginseng root extract 0.01
Dendrobium candidum stem extraction 0.05
Astragalus membranacus root extract 0.6
Performance test
Whitening efficiency assay
Essence prepared by this experiment investigation embodiment 1-4 and comparative example 1-4 inhibits situation to tyrosinase activity.
1, test method
Referring to periodical " when treasure's traditional Chinese medical science traditional Chinese medicines " volume 21 the 4th phase " angelica extract anti aging effect and whitening function in 2010 Imitate experiment in vitro research " 2.3 section whitening efficiency assay methods.
1, effect assessment
Tyrosinase inhibition rate the results are shown in Table 9.
Table 9
Group Tyrosinase inhibition rate (%)
Embodiment 1 21.1
Embodiment 2 21.4
Embodiment 3 23.6
Embodiment 4 25.3
Comparative example 1 9.3
Comparative example 2 11.9
Comparative example 3 11.3
Comparative example 4 8,5
As shown in Table 9, in tyrosinase inhibition rate test, embodiment group is significantly better than the inhibition level of tyrosinase Comparative example group, and the tyrosinase inhibition rate highest in 4 groups of embodiment are primarily due in 4 groups of embodiment also contain and releive into Point, skin microenvironment is adjusted, enters inside skin conducive to the component with white-skinned face function, inhibits tyrosinase activity, to keep away The formation for exempting from melanin, the effect of reaching mild whitening.Lack Radix Notoginseng root extract in comparative example 1 and Astragalus membranacus root extracts Object, tyrosinase inhibition rate are minimum, it is seen then that although containing two kinds of dendrobium candidum stem extraction and Angelica roots mainly at Point, it also requires the substance that can adjust skin surface microenvironment gets through skin passage, main matter is made to play effect.Comparative example Lack Angelica roots in 2, lack dendrobium candidum stem extraction in comparative example 3, in two groups to tyrosinase inhibition rate it It is all high not as good as the tyrosinase inhibition rate in 4 groups of embodiment.Although there is white-skinned face function comprising the present invention in 4 groups of comparative example Four kinds of effective components in composition, but the proportionate relationship of four kinds of ingredients does not have the composition of white-skinned face function in the present invention The column of proportion.The above results show that the ingredient of the composition with white-skinned face function of the invention is indispensable, at the same be also required to Rational proportion, which carries out interworking, can just obtain the effect of maximum synergy, to obtain optimal whitening effect.
Practical effect test
1, experimental group:
Select 20-30 years old skin of face allergic human population (there are acne, acne in face, have red capillary, patient) be test object, press 8 groups, every group 10 are randomly divided into according to embodiment 1-4, comparative example 1-4.
2, application method:
After face cleaning, the facial mask containing Essence of the present invention is taken to spread on subject face, gently pats Tie Lao face. 30min After remove facial mask, clear water is rinsed well, subject be used continuously 45 days, once a day.
3, test result:
Comprehensive score is carried out using opinion poll point system.Grade form on probation is filled in after 45 days immediately.It is every in grade form Using effect total score is 5 points, and 5 points are best result, is indicated very satisfied;4 points be it is preferable, it is relatively satisfied;3 points are that can connect By;3 points the following are unacceptable range, every using effect average situation is as shown in table 5:
Table 10
Using effect It releives, is nonirritant Moisture retention Anti-acne Dispel red capillary
Embodiment 1 4.2 4.3 3.9 3.8
Embodiment 2 4.1 4.0 4.0 4.1
Embodiment 3 4.7 4.7 4.6 4.7
Embodiment 4 4.9 4.7 5.0 4.8
Comparative example 1 2.3 3.2 2.6 2.1
Comparative example 2 3.2 3.0 3.1 3.4
Comparative example 3 3.6 3.2 3.3 3.4
Comparative example 4 3.0 3.2 3.7 3.7
Test result is as shown in table 10, and whole using effect is significantly better than control group in embodiment group.In comparative example 1 not Root extract containing Radix Notoginseng and Astragalus membranacus root extract, be able to reflect antiallergic releive the releiving of effect, nonirritant, anti-acne, It dispels and shows worst in the metrics evaluation of red capillary, also having proved Radix Notoginseng root extract and Astragalus membranacus root extract can play The effect of antiallergic is releived.Comparative example 2 to comparative example 3 lack in the present invention with white-skinned face function composition in important one at Point, indices are also relatively low, although in comparative example 4 comprising the present invention have white-skinned face function composition in four kinds effectively at Point, but the proportionate relationship of four kinds of ingredients does not have the column of the proportion of the composition of white-skinned face function, indices in the present invention It is relatively low.Embodiment 3 and embodiment 4 are releived ingredient Rosa centifolia flower extract etc. because also containing antiallergic, are releived effect assessment in antiallergic In put up the best performance.The above results show that the ingredient of the composition with white-skinned face function of the invention is indispensable, are also required to simultaneously The effect of maximum synergy can just be obtained by carrying out interworking with rational proportion, to obtain optimal whitening effect.
Each technical characteristic of embodiment described above can be combined arbitrarily, for simplicity of description, not to above-mentioned reality It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited In contradiction, all should be considered as described in this specification.
The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to protection of the invention Range.Therefore, the scope of protection of the patent of the invention shall be subject to the appended claims.

Claims (9)

1. a kind of composition with white-skinned face function, which is characterized in that the raw material components including following mass parts:
2. the composition according to claim 1 with white-skinned face function, which is characterized in that the group with white-skinned face function The component for closing object further includes glossy privet fruit extract, licorice root extract, daisy flower extract, Rosa centifolia flower extract and Jasminum officinale Linn At least one of extract.
3. the composition according to claim 2 with white-skinned face function, which is characterized in that the raw material including following mass parts Component:
4. the composition according to claim 3 with white-skinned face function, which is characterized in that the raw material including following mass parts Component:
5. a kind of cosmetics, which is characterized in that including the described in any item compositions with white-skinned face function of Claims 1-4.
6. a kind of Essence, which is characterized in that including described in any one of Claims 1-4 with white-skinned face function composition, 1.3-15.5 part moisturizer and 75-80 parts of water.
7. Essence according to claim 6, which is characterized in that the Essence further includes preservative.
8. Essence according to claim 6 or 7, which is characterized in that the moisturizer be selected from acetylation Sodium Hyaluronate, At least one of polyglutamic acid and 1.3- propylene glycol.
9. a kind of preparation method of Essence, which is characterized in that the preparation method of the Essence includes the following steps: by quality Part meter,
1.3-15.5 parts of moisturizer and 75-80 parts of water are mixed, A phase is obtained;
Composition described in claim any one of 1-4 with white-skinned face function is added in A phase and is uniformly mixed so as to obtain B phase;
Retain filtrate after the B phase is filtered to get Essence.
CN201811542372.1A 2018-12-17 2018-12-17 Composition, cosmetic and essence with whitening effect and preparation method thereof Active CN109602653B (en)

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