CN109498599A - Daily health caring sustained-release gel ointment table - Google Patents

Daily health caring sustained-release gel ointment table Download PDF

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Publication number
CN109498599A
CN109498599A CN201811503957.2A CN201811503957A CN109498599A CN 109498599 A CN109498599 A CN 109498599A CN 201811503957 A CN201811503957 A CN 201811503957A CN 109498599 A CN109498599 A CN 109498599A
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CN
China
Prior art keywords
extract
ointment
parts
sustained
magnolol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811503957.2A
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Chinese (zh)
Inventor
兰雪芬
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xuzhou Platinum Blue New Material Technology Co Ltd
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Xuzhou Platinum Blue New Material Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xuzhou Platinum Blue New Material Technology Co Ltd filed Critical Xuzhou Platinum Blue New Material Technology Co Ltd
Priority to CN201811503957.2A priority Critical patent/CN109498599A/en
Publication of CN109498599A publication Critical patent/CN109498599A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/33Cactaceae (Cactus family), e.g. pricklypear or Cereus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

Abstract

The invention discloses a kind of daily health caring sustained-release gel ointment tables, ointment is covered on nonwoven fabric base bottom, one layer of sterile plastic sheet is covered on ointment, the ointment includes following component: aloe extract, Radix et Caulis Opuntiae Dillenii extract, elderberry extract, magnolol, distilled water, sodium hyaluronate, carbomer, pH adjusting agent, edible essence.The structure that the present invention uses can be effectively isolated ointment, select the ingredients such as aloe extract, Radix et Caulis Opuntiae Dillenii extract, elderberry extract, magnolol, water melon frost extract, Fructus Monordicae extract, chrysanthemum extract have effects that eliminating inflammation and expelling toxin, can be with potent antibacterial after three's scientific compatibility use;Using the carbomer gel with slow releasing function, by sustained-release administration, there is lasting treatment and prevention effect to mouth disease;Since wound healing can be accelerated, and the edible essence added is easier to be received by children or gerontal patient, the long-term care suitable for various patients uses with long-acting bacteriostatic.

Description

Daily health caring sustained-release gel ointment table
Technical field
The present invention relates to a kind of ointment, specifically a kind of daily health caring sustained-release gel ointment table belongs to oral healthcare substance.
Background technique
Oral cavity is located at respiratory tract, gastral entrance, and specific position determines periodontal disease and the close phase of whole body health It closes.When periodontal disease occurs, there are a large amount of bacterial accumulations on facing and periodontal, form due to intestine erosion and ulcer face, have on ulceration face a large amount of When bacterial heap, daily chewing activity can be such that bacterium and toxic product enters in blood circulation, increase the risk of hologathy.It is existing Some researches show that there are interactional relationships between the diseases such as periodontosis and diabetes, heart disease and myocardial infarction.Especially It is the elderly or the weaker children of resistance, once oral cavity ulceration infects, wound is not easy to heal, and the proliferation of bacterium but will subtract The healing rate of slow wound, brings dual harm to these crowds, thus how to effectively remove the bacterium on facing and periodontal at It is at present that common antibacterial medicines are directly applied to oral cavity for the common method of oral inflammation for a urgent problem to be solved On ulcer surface, once one side irritation is strong, tongue surprisingly touches and has very strong sense of discomfort;On the other hand in the oral cavity Be easy to dissolve with saliva, drug effect it is very short, lasting antibacterial and health care can not be carried out to oral cavity.
Summary of the invention
It can persistently antibacterial, quickening wound in view of the above-mentioned problems of the prior art, the object of the present invention is to provide one kind Mouthful healing, and the daily health caring sustained-release gel ointment table of sense of discomfort will not be generated because of stimulation, can be with for the elderly or children Longlasting treatments and prevention mouth disease.
To achieve the above object, the technical solution adopted by the present invention is that: a kind of daily health caring sustained-release gel ointment table, including Nonwoven fabric base bottom is covered with ointment on the nonwoven fabric base bottom, one layer of sterile plastic sheet, the ointment is covered on ointment Including following component: aloe extract, Radix et Caulis Opuntiae Dillenii extract, elderberry extract, magnolol, distilled water, sodium hyaluronate, card Wave nurse, pH adjusting agent, edible essence.
Preferably, the mass fraction of the ointment each component are as follows: the mass fraction of each component are as follows: aloe extract 0.03-0.05 parts, 0.03-0.05 parts of Radix et Caulis Opuntiae Dillenii extract, 0.03-0.05 parts of elderberry extract, 0.5-1.0 parts of magnolol, 10-12 parts of distilled water, 3-5 parts of sodium hyaluronate, 88-90 parts of carbomer, 0.3-0.5 parts of pH adjusting agent, edible essence 0.01- 0.02 part.
Preferably, the mass fraction of the ointment each component are as follows: 0.05 part of aloe extract, Radix et Caulis Opuntiae Dillenii extract 0.05 Part, 0.05 part of elderberry extract, 0.5 part of magnolol, 10 parts of distilled water, 3 parts of sodium hyaluronate, 90 parts of carbomer, pH are adjusted 0.5 part of agent, 0.02 part of edible essence.
Preferably, the pH value of the gel of releiving is 6-7.
Preferably, the pH adjusting agent is potassium hydroxide.
In order to facilitate use, the size of the nonwoven fabric base bottom and sterile plastic sheet is all 10mm*10mm.
Compared with the existing technology, the present invention has the advantage that
(1) ointment is laid on nonwoven fabric base bottom by the present invention, can be incited somebody to action after the sterile plastic sheet of covering is opened The medical ointment plaster of exposing is on ulcer surface, and nonwoven fabric base bottom can play the role of that ointment is isolated at this time, will not be touched by tongue To, avoid the generation of sense of discomfort;And since ointment is isolated, it will not be dissolved easily with saliva contacts, substantially prolong medicine Effect.
(2) present invention selects the ingredients such as aloe extract, Radix et Caulis Opuntiae Dillenii extract, elderberry extract, magnolol, magnolol It can inhibit the formation that cariogenic bacteria growth produces acid, can prevent Dental plaque biofilm;Furthermore magnolol can also reduce inflammation part week It encloses Permeability of Capillary Wall and inhibits bacterium diffusion.Aloe extract, Radix et Caulis Opuntiae Dillenii extract, elderberry extract have anti-inflammatory The effect of removing toxic substances, three's compatible use can potent antibacterial, prevent the generation of mouth disease;Using the card wave with slow releasing function Nurse gel has lasting treatment and prevention effect to mouth disease by sustained-release administration;Due to that can be accelerated with long-acting bacteriostatic Wound healing, and the edible essence added is easier to be received by children or gerontal patient, the long-term guarantor suitable for various patients It is strong to use.
Detailed description of the invention
Fig. 1 is structural schematic diagram of the invention;
In figure, 1, nonwoven fabric base bottom, 2, ointment, 3, sterile plastic sheet.
Specific embodiment
The present invention is described in further detail below in conjunction with the accompanying drawings.
Embodiment 1
Daily health caring sustained-release gel ointment table includes nonwoven fabric base bottom 1, is covered with ointment 2 on the nonwoven fabric base bottom 1, One layer of sterile plastic sheet 3, each component and mass fraction of ointment 2 are covered on ointment 2 are as follows: 0.05 part of aloe extract, 0.05 part of Radix et Caulis Opuntiae Dillenii extract, 0.05 part of elderberry extract, 0.5 part of magnolol, 10 parts of distilled water, 3 parts of sodium hyaluronate, card 90 parts of wave nurse, 0.5 part of pH adjusting agent, 0.02 part of edible essence.
Each component is weighed by above-mentioned mass fraction, magnolol is placed in a beaker, and it is a certain amount of that distilled water dissolution configuration is added Solution filters to take clear liquid after being sufficiently stirred, then aloe extract, Radix et Caulis Opuntiae Dillenii extract, elderberry extract are added wherein, obtains Certain density mixed liquor.It takes sodium hyaluronate and carbomer to be added in beaker, distilled water is added, is placed in 30 DEG C of stirring in water bath extremely Solid is completely dissolved.It after being cooled to room temperature, is placed into blender, magnolol mixed liquor and edible essence is added while stirring, It stirs and evenly mixs, pH adjusting agent is added dropwise and adjusts pH value, until pH value forms clear gel when being 6-7, ultrasonic wave deaerates after 25min Ointment is made.
In use, the ointment 2 of exposing can be placed directly against on ulcer surface after the sterile plastic sheet 3 of covering is opened, Nonwoven fabric base bottom 1 can play the role of that ointment 2 is isolated at this time.This product is coated in the canker sore surface of a wound in daily sooner or later, Continue 5-7 days, the ulceration surface of a wound can be cured, it can antibacterial, accelerating wound healing.
Embodiment 2
Daily health caring sustained-release gel ointment table includes nonwoven fabric base bottom 1, is covered with ointment 2 on the nonwoven fabric base bottom 1, One layer of sterile plastic sheet 3, each component and mass fraction of ointment 2 are covered on ointment 2 are as follows: 0.05 part of aloe extract, 0.05 part of Radix et Caulis Opuntiae Dillenii extract, 0.05 part of elderberry extract, 1.0 parts of magnolol, 12 parts of distilled water, 5 parts of sodium hyaluronate, card 90 parts of wave nurse, 0.5 part of pH adjusting agent, 0.02 part of edible essence.
Each component is weighed by above-mentioned mass fraction, magnolol is placed in a beaker, and it is a certain amount of that distilled water dissolution configuration is added Solution filters to take clear liquid after being sufficiently stirred, then aloe extract, Radix et Caulis Opuntiae Dillenii extract, elderberry extract are added wherein, obtains Certain density mixed liquor.It takes sodium hyaluronate and carbomer to be added in beaker, distilled water is added, is placed in 30 DEG C of stirring in water bath extremely Solid is completely dissolved.It after being cooled to room temperature, is placed into blender, magnolol mixed liquor and edible essence is added while stirring, It stirs and evenly mixs, pH adjusting agent is added dropwise and adjusts pH value, until pH value forms clear gel when being 6-7, be after ultrasonic wave degassing 30min It can.
Through testing, can achieve the effect that similarly to Example 1 using after this product.
Embodiment 3
Daily health caring sustained-release gel ointment table includes nonwoven fabric base bottom 1, is covered with ointment 2 on the nonwoven fabric base bottom 1, One layer of sterile plastic sheet 3, each component and mass fraction of ointment 2 are covered on ointment 2 are as follows: 0.03 part of aloe extract, 0.03 part of Radix et Caulis Opuntiae Dillenii extract, 0.03 part of elderberry extract, 0.5 part of magnolol, 10 parts of distilled water, 3 parts of sodium hyaluronate, card 88 parts of wave nurse, 0.3 part of pH adjusting agent, 0.02 part of edible essence.
Each component is weighed by above-mentioned mass fraction, magnolol is placed in a beaker, and it is a certain amount of that distilled water dissolution configuration is added Solution filters to take clear liquid after being sufficiently stirred, then aloe extract, Radix et Caulis Opuntiae Dillenii extract, elderberry extract are added wherein, obtains Certain density mixed liquor.It takes sodium hyaluronate and carbomer to be added in beaker, distilled water is added, is placed in 30 DEG C of stirring in water bath extremely Solid is completely dissolved.It after being cooled to room temperature, is placed into blender, magnolol mixed liquor and edible essence is added while stirring, It stirs and evenly mixs, pH adjusting agent is added dropwise and adjusts pH value, until pH value forms clear gel when being 6-7, be after ultrasonic wave degassing 30min It can.
Through testing, can achieve the effect that similarly to Example 1 using after this product.

Claims (6)

1. a kind of daily health caring sustained-release gel ointment table, which is characterized in that including nonwoven fabric base bottom (1), the nonwoven fabric base It is covered on bottom (1) ointment (2), one layer of sterile plastic sheet (3) is covered on ointment (2), the ointment (2) includes such as the following group Point: aloe extract, Radix et Caulis Opuntiae Dillenii extract, elderberry extract, magnolol, distilled water, sodium hyaluronate, carbomer, pH tune Save agent, edible essence.
2. daily health caring sustained-release gel ointment table according to claim 1, which is characterized in that ointment (2) each component Mass fraction are as follows: 0.03-0.05 parts of aloe extract, 0.03-0.05 parts of Radix et Caulis Opuntiae Dillenii extract, elderberry extract 0.03- 0.05 part, 0.5-1.0 parts of magnolol, 10-12 parts of distilled water, 3-5 parts of sodium hyaluronate, 88-90 parts of carbomer, pH adjusting agent 0.3-0.5 parts, 0.01-0.02 parts of edible essence.
3. daily health caring sustained-release gel ointment table according to claim 1, which is characterized in that ointment (2) each component Mass fraction are as follows: 0.05 part of aloe extract, 0.05 part of Radix et Caulis Opuntiae Dillenii extract, 0.05 part of elderberry extract, magnolol 0.5 Part, 10 parts of distilled water, 3 parts of sodium hyaluronate, 90 parts of carbomer, 0.5 part of pH adjusting agent, 0.02 part of edible essence.
4. daily health caring sustained-release gel ointment table according to claim 1, which is characterized in that the pH value of the gel of releiving For 6-7.
5. daily health caring sustained-release gel ointment table according to claim 1, which is characterized in that the pH adjusting agent is hydrogen Potassium oxide.
6. daily health caring sustained-release gel ointment table according to claim 1, which is characterized in that the nonwoven fabric base bottom (1) and the size of sterile plastic sheet (3) is all 10mm*10mm.
CN201811503957.2A 2018-12-10 2018-12-10 Daily health caring sustained-release gel ointment table Pending CN109498599A (en)

Priority Applications (1)

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CN201811503957.2A CN109498599A (en) 2018-12-10 2018-12-10 Daily health caring sustained-release gel ointment table

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811503957.2A CN109498599A (en) 2018-12-10 2018-12-10 Daily health caring sustained-release gel ointment table

Publications (1)

Publication Number Publication Date
CN109498599A true CN109498599A (en) 2019-03-22

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112359485A (en) * 2020-11-18 2021-02-12 同高纺织化纤(深圳)有限公司 Nonwoven fabric, method for producing same, and sanitary material having same
US20220000954A1 (en) * 2018-10-31 2022-01-06 Kosa Bio Inc. Composition comprising elderberry extract as effective component for preventing, treating, or alleviating andropause syndrome

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220000954A1 (en) * 2018-10-31 2022-01-06 Kosa Bio Inc. Composition comprising elderberry extract as effective component for preventing, treating, or alleviating andropause syndrome
CN112359485A (en) * 2020-11-18 2021-02-12 同高纺织化纤(深圳)有限公司 Nonwoven fabric, method for producing same, and sanitary material having same

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Application publication date: 20190322

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