CN109481319A - A kind of micro-nano lotion of camellia oil and preparation method thereof - Google Patents
A kind of micro-nano lotion of camellia oil and preparation method thereof Download PDFInfo
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
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Abstract
The present invention relates to skin protection cosmetics fields, it is thick to solve existing camellia oil appearance presentation, daily skin nursing is inconvenient, it is bad using camellia oil skin care products sensory effects obtained by traditional emulsion process, and its partial size is big, dispersion performance in the medium is poor, is not easy to apply, it is limited the development and application of cosmetic field the problems such as, the present invention provides micro-nano lotions of a kind of camellia oil and preparation method thereof.It contains: camellia oil: 35~50%；Phosphatide: 2~8%；Antioxidant: 0.1~0.3%；Water: 2~10%；Glycerol: surplus.The present invention is reasonable to match by selecting natural safe raw material, and the micro-nano lotion of camellia oil is prepared.Obtained micro-nano emulsion particle diameter is small, and camellia oil is easier skin permeation, and absorbability is more preferable；The camellia oil mass of load is larger, can achieve the effect that preferably to moisten moisturizing；And product appearance is transparent or translucent, gives the more aesthetic experiences of consumer.
Description
Technical field
The present invention relates to skin protection cosmetics fields more particularly to a kind of micro-nano lotion of camellia oil and preparation method thereof.
Background technique
Camellia oil also known as tea oil, camellia seed oil etc..Camellia oil by fatty acid, camellin, Phospholipids, saponin(e, vitamin E,
Tannin etc. is at being grouped as.The unsaturated fatty acid content of tea oil is abundant, and up to 85% or more, fatty acid forms and olive oil pole
It is close.Camellia oil can effectively prevent cardiovascular disease as edible oil, enhance immune function, accelerate the benefits such as absorption.Mountain
Tea oil also has effects that good skin care, moisturizing.Studies have shown that the component part 70~80% and human skin one of camellia oil
Sample, skin-friendly is good, can maintain Skin Cell normal physiological function and metabolic activity.
The presentation of camellia oil appearance is thick, and daily skin nursing is inconvenient.Traditional emulsion process, sensory effects are bad,
And its partial size is big, dispersion performance in the medium is poor, is not easy to apply, and limits it in the development and application of cosmetic field.
In order to solve the above problem, Patent Office of the People's Republic of China camellia oil microemulsion and its preparation side disclosed on September 2nd, 2015
Method authorizes the invention granted patent of Publication No. CN103283866B to provide a kind of solution, in the skill of the patent of invention
In art scheme, the camellia oil microemulsion includes: 5~70% surfactants, 2~30% cosurfactants, 0.5~10%
Liquid fat acid, 0.1~4% camellia oil and 0~90% water.This improves the dispersion performance of camellia oil in the medium and surely
Camellia oil, is prepared into transparent liquid by qualitative energy, is improved camellia oil to a certain extent and is not directly applicable lacking for water
Point.But the camellia oil content loaded in the program is too low, the amount of surfactant used is excessive, not only to the protection of skin,
Nursing efficacy is extremely limited, it is easier to cause to stimulate to skin, there are application risks.
And Patent Office of the People's Republic of China also disclosed a kind of Refining-free natural tea seed skincare oil and its preparation on May 28th, 2014
The invention patent mandate of method authorizes Publication No. CN102885753B, is made of the following component of quality proportioning: tea-seed oil
80-98 parts, 1.0-19 parts of plants essential oil, 15-30 parts of linolenic acid, 2.5-5 parts of tea polyphenols, 5-10 parts of vitamin E, sheep placenta 1-2
Part.According to said ratio, by tea-seed oil, plants essential oil, linolenic acid, tea polyphenols, vitamin E, sheep placenta, emulsifier, emollient,
Moisturizer and stabilizer are stirred and heated to 50-55 DEG C, and mixing preparation is uniform, obtain product.The program is able to maintain tea seed
Natural activity and nutritional ingredient improve the skin-care function of skin care oil, have whitening and skin-protecting, inoxidizability strong and radiation protection
Etc. functions.But the program there is oil droplet sizes big, bad dispersibility, whole sense organ is sticky, skin is not easy the disadvantages of absorbing.
Patent Office of the People's Republic of China, which discloses one kind on October 8th, 2014, prevents dry skin chap moisturizing product and preparation method thereof
Invention patent mandate, authorize Publication No. CN103301035B, it includes the components of following mass percent: plant society oil
Rouge: 1~10%；The plant society grease includes wheat-germ oil, Seabuckthorn Oil and camellia oil, the wheat-germ oil, sea-buckthorn
The mass ratio of oil and camellia oil is 1:2:3~1:3:6.But it also contains a large amount of Synthetic Oils and emulsifier component, to skin
Compatibility is poor, equally exist it is easy skin is caused to stimulate, the problems such as there are application risks.
Summary of the invention
Thick to solve existing camellia oil appearance presentation, daily skin nursing is inconvenient, using traditional emulsification
Camellia oil skin care products sensory effects obtained by method are bad, and its partial size is big, and dispersion performance in the medium is poor, are not easy to answer
With, limit it the development and application of cosmetic field the problems such as, the present invention provides a kind of micro-nano lotion of camellia oil and its
Preparation method.It first has to be accomplished that by reducing emulsion droplet partial size, improving the micro-nano lotion of camellia oil and human skin
Compatibility, the whole purpose for improving skin effect, and improve the sense organ of the micro-nano lotion of camellia oil on this basis and guarantee it
Safety in utilization etc..
To achieve the above object, the invention adopts the following technical scheme:
A kind of camellia oil micro-nano lotion contains by weight percentage in the micro-nano lotion of camellia oil:
Camellia oil: 35~50%；
Phosphatide: 2~8%；
Antioxidant: 0.1~0.3%；
Water: 2~10%；
Glycerol: surplus.
Contain multiple nutritional components in camellia oil: unsaturated fatty acid, vitamin and mineral etc. have been arranged as drug
Enter " Chinese Pharmacopoeia ", very long history is also possessed for skin disease quality.And also contain tea polyphenols and squalene in camellia oil
Equal substances have ability that is anti-oxidant well and repairing skin barrier.Therefore the present invention is using camellia oil as primary raw material pair
The affinity of human body and to the very outstanding of skin effect caused by skin.Phosphatide is almost present in all body cells
In, more phosphatide is all contained in animal and plant body vital tissue, it can be with protein, glycolipid and cholesterol etc. as emulsifier
Other molecules collectively form lipid bilayer, the i.e. structure of cell membrane, therefore while playing emulsification, additionally it is possible into one
Walk the effect that the reparation of protection is realized to skin.And after using glycerol substitution water, glycerol is in addition to rising in whole emulsifier system
To outside the effect of moisturizing skin, the effect as outer phase solvent is also acted as.Improve product sense organ, keeps product more saturating
It is bright, it is usually required mainly for consider two factors: first is that index of refraction, interior phase and foreign minister's index of refraction are transparent close to being more easily done, to select sweet
The oily rather than solvent based on water, being primarily due to glycerol not only has preferable moistening effect, and the index of refraction of glycerol
Closer to camellia oil；Second influence factor is size droplet diameter, and partial size is smaller, and easier presentation is transparent in appearance.
Preferably, containing by weight percentage in the micro-nano lotion of camellia oil:
Camellia oil: 40~45%；
Phosphatide: 3~6%；
Antioxidant: 0.15~0.25%；
Water: 5~8%；
Glycerol: surplus.
The micro-nano lotion of camellia oil of weight percent content composition has more preferably using effect.
Preferably, the phosphatide is lecithin or hydrolecithin.
Lecithin and hydrolecithin are used for many years in food and drug by maturation, and itself are human cell membrane
Important component, it is good with human skin compatibility, safety, in addition to playing good emulsifying effectiveness, can also play
Repair the effect of skin barrier and skin care.
Preferably, in the phosphatide phosphatidyl choline content >=75wt%.
Phosphatidylcholine content is higher, better to human body compatibility, the reparation skin barrier and skin care played
Effect it is also more preferable.
Preferably, the antioxidant is vitamin E or Rosmarinus officinalis extract.
Vitamin E is preferably natural VE, and antioxidant is preferably natural.The choosing of natural
It is good anti-oxidant in addition to that can play with can be avoided the problems such as causing synthetic to stimulate caused by human skin
It is higher to the compatibility of human body other than effect.
A kind of preparation method of the micro-nano lotion of camellia oil, the preparation method includes following preparation step:
1) phosphatide is added and is stirred evenly into glycerol, water is added, is stirred under heating to phosphatide and is uniformly dissolved, it is stand-by as A phase；
2) antioxidant and camellia oil are uniformly mixed, as B phase, obtain pretreatment fluid after B is added to the stirring of A phase high speed；
3) by pretreatment fluid by microjet high pressure homogenizer, cooling makes its temperature≤37 DEG C to get micro- to camellia oil after discharging
Nanoemulsions.
Preparation method of the present invention is succinct, and passes through microjet high pressure homogenizer and select suitable homogenization pressure and circulation
The micro-nano lotion of the minimum camellia oil of partial size can be prepared in number.
Preferably, step 1) the heating stirring process is warming up to 60~65 DEG C.
The too low then stirring and dissolving of temperature is excessively slow, mixing effect is poor and inefficiency, and temperature is excessively high, be easy to cause phosphatide
Situations such as ingredient is destroyed.
Preferably, step 2) the high-speed stirred revolving speed is 5000~6000rpm.
The revolving speed can efficiently mix A phase and B phase.
Preferably, the step 2) high-speed stirred carries out 5~10min.
The too short then uniformity of mixing time is poor, and mixing time is too long, reduces efficiency and causes to waste.
Preferably, the step 3) pretreatment fluid pass through microjet high pressure homogenizer when, setting homogenization pressure be 150~
250MPa is recycled 2~5 times.
The micro-nano lotion of the suitable camellia oil of partial size can be prepared under the conditions of the homogenization pressure and cycle-index.
The beneficial effects of the present invention are:
1) raw material selected is naturally safe, more preferably to human body compatibility；
2) the micro-nano emulsion particle diameter obtained is small, and camellia oil is easier skin permeation, and absorbability is more preferable；
3) the camellia oil mass loaded is larger, can achieve the effect that preferably to moisten moisturizing, and matches rationally, can keep for a long time steady
It is fixed；
4) product appearance is transparent or translucent, gives the more aesthetic experiences of consumer.
Specific embodiment
Further clear detailed description explanation is made to the present invention below in conjunction with specific embodiment.Ordinary skill
Personnel will realize the present invention based on these explanations.In addition, the reality of the invention being related in following the description
The embodiment that example is generally only a branch of the invention is applied, instead of all the embodiments.Therefore, based on the implementation in the present invention
Example, those of ordinary skill in the art's every other embodiment obtained without making creative work, is all answered
When belonging to the scope of protection of the invention.
Unless otherwise specified, the raw materials used present invention is market is commercially available or those skilled in the art obtained by original
Material；Unless otherwise specified, method therefor of the present invention is the method that those skilled in the art are grasped.And in the embodiment of the present invention
The phosphatidylcholine content of lecithin and hydrolecithin used is all larger than equal to 75wt%.
Embodiment 1
A kind of micro-nano lotion of camellia oil of 1Kg is prepared, ingredient:
Camellia oil: 450g；
Lecithin: 60g；
Rosmarinus officinalis extract: 1g；
Water: 70g；
Glycerol: 419g；
Preparation method includes following preparation step:
1) 60g lecithin is added into 419g glycerol and is stirred evenly, 70g water is added, be again heated to 50 DEG C and stirred to lecithin
Rouge is uniformly dissolved, stand-by as A phase；
2) 1g Rosmarinus officinalis extract and 450g camellia oil are uniformly mixed, as B phase, B is added into A phase with 5000rpm
Revolving speed high-speed stirred 5min after obtain pretreatment fluid；
3) by pretreatment fluid by microjet high pressure homogenizer, setting homogenization pressure is 200MPa, cycle-index is 3 times, discharging
After be slowly stirred cooling and make its temperature≤37 DEG C to get to the micro-nano lotion of camellia oil.
Embodiment 2
A kind of micro-nano lotion of camellia oil of 1Kg is prepared, ingredient:
Camellia oil: 500g；
Hydrolecithin: 75g；
Rosmarinus officinalis extract: 2g；
Water: 50g；
Glycerol: 373g；
Preparation method includes following preparation step:
1) 75g hydrolecithin is added into 373g glycerol and is stirred evenly, 50g water is added, be again heated to 60 DEG C and stirred extremely
Hydrolecithin is uniformly dissolved, stand-by as A phase；
2) 2g Rosmarinus officinalis extract and 500g camellia oil are uniformly mixed, as B phase, B is added into A phase with 6000rpm
Revolving speed high-speed stirred 10min after obtain pretreatment fluid；
3) by pretreatment fluid by microjet high pressure homogenizer, setting homogenization pressure is 250MPa, cycle-index is 2 times, discharging
Standing cooling afterwards makes its temperature≤37 DEG C to get the micro-nano lotion of camellia oil is arrived.
Embodiment 3
A kind of micro-nano lotion of camellia oil of 1Kg is prepared, ingredient:
Camellia oil: 350g；
Lecithin: 35g；
Rosmarinus officinalis extract: 1g；
Water: 30g；
Glycerol: 584g；
Preparation method includes following preparation step:
1) 35g lecithin is added into 584g glycerol and is stirred evenly, 30g water is added, be again heated to 60 DEG C and stirred to lecithin
Rouge is uniformly dissolved, stand-by as A phase；
2) 1g Rosmarinus officinalis extract and 350g camellia oil are uniformly mixed, as B phase, B is added into A phase with 6000rpm
Revolving speed high-speed stirred 8min after obtain pretreatment fluid；
3) by pretreatment fluid by microjet high pressure homogenizer, setting homogenization pressure is 150MPa, cycle-index is 5 times, discharging
Standing cooling afterwards makes its temperature≤37 DEG C to get the micro-nano lotion of camellia oil is arrived.
Embodiment 4
A kind of micro-nano lotion of camellia oil of 1Kg is prepared, ingredient:
Camellia oil: 400g；
Hydrolecithin: 20g；
Natural VE: 3g；
Water: 20g；
Glycerol: 457g；
Preparation method includes following preparation step:
1) 20g hydrolecithin is added into 457g glycerol and is stirred evenly, 20g water is added, be again heated to 60 DEG C and stirred extremely
Hydrolecithin is uniformly dissolved, stand-by as A phase；
2) 3g natural VE and 400g camellia oil are uniformly mixed, as B phase, B is added into A phase with 5000rpm's
Pretreatment fluid is obtained after revolving speed high-speed stirred 10min；
3) by pretreatment fluid by microjet high pressure homogenizer, setting homogenization pressure is 200MPa, cycle-index is 4 times, discharging
After be slowly stirred cooling and make its temperature≤37 DEG C to get to the micro-nano lotion of camellia oil.
Embodiment 5
A kind of micro-nano lotion of camellia oil of 1Kg is prepared, ingredient:
Camellia oil: 500g；
Lecithin: 80g；
Natural VE: 2g；
Water: 100g；
Glycerol: 318g；
Preparation method includes following preparation step:
1) 80g lecithin is added into 318g glycerol and is stirred evenly, 100g water is added, be again heated to 65 DEG C and stirred to lecithin
Rouge is uniformly dissolved, stand-by as A phase；
2) 2g natural VE and 500g camellia oil are uniformly mixed, as B phase, B is added into A phase with 5000rpm's
Pretreatment fluid is obtained after revolving speed high-speed stirred 7min；
3) by pretreatment fluid by microjet high pressure homogenizer, setting homogenization pressure is 200MPa, cycle-index is 3 times, discharging
Standing cooling afterwards makes its temperature≤37 DEG C to get the micro-nano lotion of camellia oil is arrived.
Embodiment 6
A kind of micro-nano lotion of camellia oil of 1Kg is prepared, ingredient:
Camellia oil: 450g；
Hydrolecithin: 30g；
Natural VE: 2.5g；
Water: 80g；
Glycerol: 437.5g；
Preparation method includes following preparation step:
1) 30g hydrolecithin is added into 437.5g glycerol and is stirred evenly, 80g water is added, is again heated to 60 DEG C and stirs
It is uniformly dissolved to hydrolecithin, it is stand-by as A phase；
2) 2.5g natural VE and 450g camellia oil are uniformly mixed, as B phase, B is added into A phase with 5000rpm
Revolving speed high-speed stirred 10min after obtain pretreatment fluid；
3) by pretreatment fluid by microjet high pressure homogenizer, setting homogenization pressure is 200MPa, cycle-index is 4 times, discharging
After be slowly stirred cooling and make its temperature≤37 DEG C to get to the micro-nano lotion of camellia oil.
Embodiment 7
A kind of micro-nano lotion of camellia oil of 1Kg is prepared, ingredient:
Camellia oil: 400g；
Lecithin: 60g；
Natural VE: 1.5g；
Water: 50g；
Glycerol: 488.5g；
Preparation method includes following preparation step:
1) 60g lecithin is added into 488.5g glycerol and is stirred evenly, 50g water is added, be again heated to 65 DEG C and stirred to ovum
Phosphatide is uniformly dissolved, stand-by as A phase；
2) 1.5g natural VE and 400g camellia oil are uniformly mixed, as B phase, B is added into A phase with 5000rpm
Revolving speed high-speed stirred 7min after obtain pretreatment fluid；
3) by pretreatment fluid by microjet high pressure homogenizer, setting homogenization pressure is 200MPa, cycle-index is 3 times, discharging
Standing cooling afterwards makes its temperature≤37 DEG C to get the micro-nano lotion of camellia oil is arrived.
The micro-nano lotion of camellia oil obtained by Examples 1 to 7 is detected, the testing result of part physicochemical property is such as
Shown in following table table 1.
On this basis, with Examples 1 to 7 it is randomly ordered and at random be added two kinds of commercially available camellia fat liquor, choose 60
The self-assessment of subject is carried out using questionnaire form, and index includes appearance favorable rating, smear, infiltration rate, taste
Moisten moisturizing etc..According to the use feeling of subject using 1~10 point of scoring point system assessment, 1~4 point indicates general, four points or more
Seven points of following presentations are also possible that 7~10 points indicate fine.Its result is as shown in following table table 2.
2 skin sense of table and product efficacy evaluation
From upper table as it can be seen that being much better than in the appearance of the micro-nano lotion of camellia oil of the present invention, various aspects using effect commercially available
Camellia fat liquor, it is whole to be better than commercially available camellia fat liquor.
Claims (10)
1. a kind of micro-nano lotion of camellia oil, which is characterized in that contain by weight percentage in the micro-nano lotion of camellia oil
Have:
Camellia oil: 35~50%；
Phosphatide: 2~8%；
Antioxidant: 0.1~0.3%；
Water: 2~10%；
Glycerol: surplus.
2. the micro-nano lotion of a kind of camellia oil according to claim 1, which is characterized in that the micro-nano lotion of camellia oil
In contain by weight percentage:
Camellia oil: 40~45%；
Phosphatide: 3~6%；
Antioxidant: 0.15~0.25%；
Water: 5~8%；
Glycerol: surplus.
3. the micro-nano lotion of a kind of camellia oil according to claim 1 or 2, which is characterized in that the phosphatide is lecithin
Or hydrolecithin.
4. the micro-nano lotion of a kind of camellia oil according to claim 3, which is characterized in that phosphatidyl choline in the phosphatide
Content >=75wt%.
5. the micro-nano lotion of a kind of camellia oil according to claim 1 or 2, which is characterized in that the antioxidant is dimension
Raw element E or Rosmarinus officinalis extract.
6. a kind of preparation method of the micro-nano lotion of the camellia oil as described in claim 1 to 5 any one, which is characterized in that institute
Stating preparation method includes following preparation step:
1) phosphatide is added and is stirred evenly into glycerol, water is added, is stirred under heating to phosphatide and is uniformly dissolved, it is stand-by as A phase；
2) antioxidant and camellia oil are uniformly mixed, as B phase, are pre-processed after B is added to the stirring of A phase high speed
Liquid；
3) by pretreatment fluid by microjet high pressure homogenizer, cooling makes its temperature≤37 DEG C to get micro- to camellia oil after discharging
Nanoemulsions.
7. a kind of preparation method of the micro-nano lotion of camellia oil according to claim 6, which is characterized in that step 1) is described
Heating stirring process is warming up to 60~65 DEG C.
8. a kind of preparation method of the micro-nano lotion of camellia oil according to claim 6, which is characterized in that step 2) is described
High-speed stirred revolving speed is 5000~6000rpm.
9. a kind of preparation method of the micro-nano lotion of camellia oil according to claim 8, which is characterized in that step 2) is described
High-speed stirred carries out 5~10min.
10. a kind of preparation method of the micro-nano lotion of camellia oil according to claim 6, which is characterized in that step 3) institute
When stating pretreatment fluid by microjet high pressure homogenizer, setting homogenization pressure is 150~250MPa, is recycled 2~5 times.
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| CN109806221A (en) * | 2019-03-21 | 2019-05-28 | 成都律恩泽雅科技有限公司 | A kind of anti-ageing composition and preparation method thereof |
| CN110075018A (en) * | 2019-04-24 | 2019-08-02 | 杭州犇鑫科技有限公司 | One kind includes tea polyphenols and the micro-nano lotion of fibroin Haircare composition and preparation method thereof |
| CN110075018B (en) * | 2019-04-24 | 2022-09-09 | 杭州犇鑫科技有限公司 | Hair care composition micro-nano emulsion containing tea polyphenol and fibroin and preparation method thereof |
| CN110846161A (en) * | 2019-11-28 | 2020-02-28 | 上海绿瑞生物科技有限公司 | Soap-based composition for personal washing care |
| CN110846161B (en) * | 2019-11-28 | 2021-07-13 | 上海绿瑞生物科技有限公司 | Soap-based composition for personal washing care |
| CN111184656A (en) * | 2020-01-22 | 2020-05-22 | 杭州千岛湖天鑫有限公司 | Skin barrier repair micro-nano emulsion containing camellia oil and preparation method thereof |
| CN114869795A (en) * | 2022-03-29 | 2022-08-09 | 上海肤徕生物高科技有限公司 | Preparation method of whitening composition for improving solubility of active components, product and application thereof |
| CN114869795B (en) * | 2022-03-29 | 2024-01-26 | 上海肤徕生物高科技有限公司 | Preparation method of whitening composition, product and application thereof |
| CN115868591A (en) * | 2022-12-19 | 2023-03-31 | 宁德九展农业有限公司 | Tea oil nanoemulsion and preparation method thereof |
| CN117017836A (en) * | 2023-08-09 | 2023-11-10 | 科乐美(广州)生物科技有限公司 | Skin care product, vegetable fat nano-particles and preparation method thereof |
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