CN109420117A - One group for treating the Chinese medicine of gout - Google Patents
One group for treating the Chinese medicine of gout Download PDFInfo
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Abstract
The invention discloses one group for treating the Chinese medicine of gout, to solve the problems, such as that current drug cannot eradicate gout.It includes the substance of following parts by weight: Radix Angelicae Pubescentis 15-25g, Radix Angelicae Sinensis 6-12g, Radix Astragali 6-12g, Caulis Spatholobi 3-9g, safflower 5-15g, Radix Salviae Miltiorrhizae 3-9g, Radix Notoginseng 5-15g, peach kernel 6-12g, tuber of pinellia 3-9g, medicine xiaolingxian 3-9g, turmeric 6-12g, cuttlebone 5-15g, gleditsia sinensis 5-15g, Radix Glycyrrhizae 3-9g.The advantage of the invention is that used Chinese medicine is without side-effects, safe and reliable, curative for effect, quick, cure rate is high.
Description
Technical field
The invention belongs to field of medicaments, and in particular to one group for treating the Chinese medicine of gout.
Background technique
Gout is the crystal correlation arthropathy caused by monosodium urate salt (MSU) deposition, with purine metabolic disturbance or urine
Hyperuricemia caused by acid excretion is reduced is directly related, refers in particular to acute characteristic arthritis and chronic gout stone disease, mainly
Including acute attack arthritis, tophus formation, tophaceous chornic arthritis, urate nephropathy and uric acid urinary tract knot
Stone, severe one may occur in which joint deformity and renal insufficiency.Gout is often with Central obesity, hyperlipidemia, hypertension, type-II diabetes
And the performance such as cardiovascular disease.The most important biochemical basis of gout is hyperuricemia.Normal adult about generates uric acid daily
750mg, wherein 80% is endogenous, 20% is exogenous uric acid, these uric acid enter uric acid metabolism pond (about 1200mg), daily
Uric acid about 60% in metabolic pool is metabolized, wherein 1/3 about 200mg, through enteron aisle catabolism, 2/3 about 400mg is arranged through kidney
It lets out, so as to maintain the stabilization of internal uric acid level, any of them link, which goes wrong, can lead to hyperuricemia.Patient is normal
White powder is discharged after the yellow-white neoplasm and ulceration that have tired, general malaise, joint sting, subcutaneous protuberance skin surface poor
The symptoms such as shape or paste, the red and swollen heat pain of Lower Distal Extremities single joint and dysfunction.
The treatment of gout, it is desirable that into low purine low-calorie diet, keep reasonable weight, abstinence from alcohol is drunk more water, every daily drink
2000ml or more.It avoids gluttony, indulge in excessive drinking, dampness of suffering from cold, over fatigue and stress, wear Comfortable shoes, prevent joint injury.?
Non-steroid anti-inflammatory drug can be selected, colchicin, glucocorticoid, uric acid is inhibited to generate medicine, uricosureic agent, novel drop urine
The drugs such as sour medicine, Allopurinol are treated, but effect is unobvious.On the market there are also treatment gout Chinese medicine, though these medicines
So there is certain curative effect, but that there is doses is big, the time is long and the problem of cannot eradicating gout.
Summary of the invention
The object of the present invention is to provide one group for treating the Chinese medicine of gout, gout cannot be eradicated to solve current drug
The problem of.
Technical scheme is as follows: one group, for treating the Chinese medicine of gout, is made of: solely the raw material of following parts by weight
15-25g, Radix Angelicae Sinensis 6-12g, Radix Astragali 6-12g, Caulis Spatholobi 3-9g, safflower 5-15g, Radix Salviae Miltiorrhizae 3-9g, Radix Notoginseng 5-15g, peach kernel 6- living
12g, tuber of pinellia 3-9g, medicine xiaolingxian 3-9g, turmeric 6-12g, cuttlebone 5-15g, gleditsia sinensis 5-15g, Radix Glycyrrhizae 3-9g.
Preferably, the parts by weight group of each raw material becomes, Radix Angelicae Pubescentis 20g, Radix Angelicae Sinensis 9g, Radix Astragali 9g, Caulis Spatholobi 6g, safflower 10g, pellet
Join 6g, Radix Notoginseng 10g, peach kernel 9g, tuber of pinellia 6g, medicine xiaolingxian 6g, turmeric 9g, cuttlebone 10g, gleditsia sinensis 10g, Radix Glycyrrhizae 6g.
Said medicine preparation process is as follows: by material medicine Radix Angelicae Pubescentis, Radix Angelicae Sinensis, Radix Astragali, Caulis Spatholobi, safflower, Radix Salviae Miltiorrhizae, Radix Notoginseng,
Peach kernel, the tuber of pinellia, medicine xiaolingxian, turmeric, cuttlebone, gleditsia sinensis, Radix Glycyrrhizae, are respectively prepared medicine materical crude slice, by pressure cooker cooking disinfection 30-45 points
Clock dries, and obtains aseptic raw material, then Chinese materia medica preparation is made in aseptic raw material to take.
Radix Angelicae Pubescentis has dispelling wind and eliminating dampness in the present invention, and the function of numbness relieving and pain relieving is monarch drug in a prescription.Radix Angelicae Sinensis, Radix Astragali, Caulis Spatholobi, safflower, pellet
Ginseng, Radix Notoginseng, peach kernel, the tuber of pinellia, medicine xiaolingxian replenishing and activating blood, regulating menstruation and relieving pain, moistening intestines and relaxing bowels, tonifying Qi and lifting yang, strengthening exterior and reducing sweat, inducing diuresis for removing edema,
Shengjin nourishing, move stagnation and palsy, pus draining and toxin expelling, expelling pus and promoting granulation, relaxing tendons and activating collaterals, dissolving stasis, promoting menstruation, relieving restlessness and restlessness, cool blood to disappear carbuncle dissipate the stasis of blood
Hemostasis, detumescence ding-tong is relieving cough and asthma, eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, relieve heat clearing damp, and breaking blood and promoting the circulation of qi is ministerial drug.Sea
The egg capsule of a mantis, gleditsia sinensis astringing to arrest bleeding, relieving leukorrhea by astringents, hyperacidity and pain relief, hygroscopic sore, eliminating the phlegm are had one's ideas straightened out for adjutant.Radix Glycyrrhizae is invigorated the spleen and benefited qi, moistening lung
Cough-relieving, it is clearing heat and detoxicating, alleviate analgesic, coordinating the drug actions of a prescription is to make medicine.
The pharmacological property and its effect of each component of the present invention are as follows:
Radix Angelicae Pubescentis, slightly warm in nature, acrid flavour, hardship return kidney, bladder meridian.Major function: dispelling wind and eliminating dampness, arthritis analgesic.The major functions: chill is wet
Numbness will wash pain, few the moon volt wind headache, headache caused by cold and dampness.
Radix Angelicae Sinensis, meridian distribution of property and flavor: it is warm-natured, it is sweet in flavor, pungent, return liver, the heart, the spleen channel.Major function: replenishing and activating blood, menstruction regulating and pain relieving,
Relax bowel and defecation.The major functions: blood deficiency chlorosis, dizziness palpitaition, irregular menstruation, amenorrhea and algomenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down,
Ulcer sores, dry constipation of intestines.
Radix Astragali, meridian distribution of property and flavor: slightly warm in nature, sweet in flavor, returns spleen, lung channel.Major function: tonifying Qi and lifting yang, strengthening exterior and reducing sweat, Li Shui disappear
It is swollen, shengjin nourishing, move stagnation and palsy, pus draining and toxin expelling, expelling pus and promoting granulation.The major functions: deficiency of vital energy and acking in strength, anorexia and loose stool, the sinking of qi of middle-jiao, chronic diarrhea are de-
Anus, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy and edema, Heat Diabetes, blood deficiency chlorosis, hemiplegia, numbness pain is numb, ulcer is difficult to burst, long
It bursts and does not hold back.
Caulis Spatholobi, it is warm-natured, it is bitter, sweet, return liver and kidney channel.Major function: blood circulation promoting and enriching, menstruction regulating and pain relieving, relaxing tendons and activating collaterals.It is main
It controls: irregular menstruation, dysmenorrhea, menostasis, rheumatic arthralgia, paralysis and numbness, blood deficiency chlorosis.
Safflower, warm-natured, acrid flavour, converge to heart and liver channels.Major function: blood circulation, stasis eliminatings analgesic.The major functions: menostasis, abdominal mass,
Difficult labour, stillborn foetus, disease that postpartum lochia can't go, hemostasis are had a pain, carbuncle swells, injury from falling down.
Radix Salviae Miltiorrhizae, meridian distribution of property and flavor: cold nature, bitter, converge to heart and liver channels.Major function: promoting blood circulation, inducing meastruation to relieve menalgia, clear away heart-fire and remove
It is tired, cool blood to disappear carbuncle.The major functions: chest impediment and cardialgia, stomach duct and abdomen hypochondriac pain, the accumulation of lump in the abdomen lump in the abdomen, hot numbness pain, dysphoria and insomnia, irregular menstruation, dysmenorrhea warp
It closes, sore swell and ache curative.
Radix Notoginseng, warm-natured, sweet in flavor, slight bitter returns liver, stomach meridian.Major function: dissipating stasis and stanching bleeding, detumescence ding-tong.The major functions: hemoptysis,
It spits blood, bleeding from five sense organs or subcutaneous tissue, hematochezia, metrorrhagia and metrostaxis, traumatic hemorrhage, chest and abdomen shouting pain, tumbling and swelling.
Peach kernel, mild-natured, bitter, sweet, return heart, liver, large intestine channel.Major function: promoting blood circulation, relax bowel and defecation, cough-relieving are flat
Asthma.The major functions: amenorrhea and algomenorrhea, lump in the abdomen lump in the abdomen lump in the abdomen, pulmonary abscess acute appendicitis, injury from falling down, dry constipation of intestines, cough and asthma.
The tuber of pinellia, warm-natured, acrid flavour, returns spleen, stomach, lung channel.Major function: eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.It is main
Control: damp phlegm is trembled with fear phlegm, cough and phlegm, phlegm retention anti-dazzle nervous, anemophlegmatic vertigo, phlegm and headache, vomiting gastric disorder causing nausea, chest gastral cavity ruffian, and globus hysteriocus is controlled outside
Carbuncle swells subcutaneous nodule.
Medicine xiaolingxian, meridian distribution of property and flavor: warm-natured, acrid flavour, salty, return 12 warps.Major function: relieve heat clearing damp, promoting qi circulation and removing obstruction in the collateral.The major functions:
Rheumatic arthralgia, paralysis are numb.
Turmeric, warm-natured, acrid flavour, hardship, returns spleen, Liver Channel.Major function: breaking blood and promoting the circulation of qi, relieving pain of dysmenorrhea.The major functions: chest side of body is pierced
Bitterly, chest impediment and cardialgia, dysmenorrhea menostasis, abdominal mass, rheumatism shoulder arm pain, tumbling and swelling.
Cuttlebone, warm-natured, taste is salty, puckery, returns spleen, kidney channel.Major function: astringing to arrest bleeding, relieving leukorrhea by astringents, hyperacidity and pain relief are received
Wet sore.The major functions: hematemesis and epistaxis, metrorrhagia and metrostaxis hematochezia, emission and spermatorrhea, leukorrhea with reddish discharge, acid regurgitation of having a stomachache；Bleeding due to trauma is controlled outside, eczema is wet
Sore, unhealing ulcer.
Gleditsia sinensis, warm-natured, acrid flavour, return lung, large intestine channel.Major function: eliminating the phlegm is had one's ideas straightened out.The major functions: apoplexy or epilepsy, sputum gush
It contains, many coughs of phlegm.
Radix Glycyrrhizae, mild-natured, sweet in flavor, return 12 warps.Major function: invigorating the spleen and benefiting qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, emergency is stopped
Bitterly, coordinating the drug actions of a prescription.The major functions: weakness of the spleen and the stomach, fatigue and weakness, shortness of breath and palpitation, coughing with a lot of sputum, stomach duct and abdomen, four limbs contraction, carbuncle swells sore
Poison alleviates drug toxicity, strong.
The Chinese medicine that the present invention treats gout has dispelling wind and eliminating dampness, numbness relieving and pain relieving, replenishing and activating blood, menstruation regulating, relax bowel and defecation, tonifying Qi
Rising Yang, strengthening exterior and reducing sweat, inducing diuresis for removing edema, shengjin nourishing, stagnant, the pus draining and toxin expelling of row, expelling pus and promoting granulation, relaxing tendons and activating collaterals, promoting menstruation clear away heart-fire and remove
Tired, cool blood to disappear carbuncle, dissipating stasis and stanching bleeding, detumescence ding-tong is relieving cough and asthma, eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, breaking blood and promoting the circulation of qi, receives
Hemostasis is held back, relieving leukorrhea by astringents, relieving haperacidity, hygroscopic, eliminating the phlegm has one's ideas straightened out, invigorates the spleen and benefits qi, clearing heat and detoxicating, emergency, the effect of coordinating the drug actions of a prescription, and treats
Effect is significant, and quick, securely and reliably, no obvious toxic-side effects can effectively treat gout.
Specific embodiment
The following examples can further illustrate the present invention, but do not limit the invention in any way.
Embodiment 1, the drug for treating gout form: Radix Angelicae Pubescentis 20g, Radix Angelicae Sinensis 9g, Radix Astragali 9g, Caulis Spatholobi 6g, safflower
10g, Radix Salviae Miltiorrhizae 6g, Radix Notoginseng 10g, peach kernel 9g, tuber of pinellia 6g, medicine xiaolingxian 6g, turmeric 9g, cuttlebone 10g, gleditsia sinensis 10g, Radix Glycyrrhizae 6g.This reality
It is best to apply an effect.
Embodiment 2, the drug for treating gout form: Radix Angelicae Pubescentis 25g, Radix Angelicae Sinensis 12g, Radix Astragali 12g, Caulis Spatholobi 9g, safflower
15g, Radix Salviae Miltiorrhizae 9g, Radix Notoginseng 15g, peach kernel 12g, tuber of pinellia 9g, medicine xiaolingxian 9g, turmeric 12g, cuttlebone 15g, gleditsia sinensis 15g, Radix Glycyrrhizae 9g.This
Embodiment drug effect is stronger.
Embodiment 3, for treat gout drug form: Radix Angelicae Pubescentis 15g, Radix Angelicae Sinensis 6g, Radix Astragali 6g, Caulis Spatholobi 3g, safflower 5g,
Radix Salviae Miltiorrhizae 3g, Radix Notoginseng 5g, peach kernel 6g, tuber of pinellia 3g, medicine xiaolingxian 3g, turmeric 6g, cuttlebone 5g, gleditsia sinensis 5g, Radix Glycyrrhizae 3g.Embodiment drug effect is slightly
It is weak.
Above-described embodiment preparation process is as follows: Radix Angelicae Pubescentis, Radix Angelicae Sinensis, Radix Astragali, Caulis Spatholobi, safflower, Radix Salviae Miltiorrhizae, Radix Notoginseng, peach kernel, half
Summer, medicine xiaolingxian, turmeric, cuttlebone, gleditsia sinensis, Radix Glycyrrhizae, are respectively prepared medicine materical crude slice, by pressure cooker cooking disinfection 30-45 minutes, dry,
Aseptic raw material is obtained, then Chinese materia medica preparation is made in aseptic raw material to take, in each 1 time of daily evening in morning, 7 as a treatment course.
" clinical trial "
For the curative effect for showing drug of the present invention, take 300 patients for being diagnosed as gout, cardinal symptom be tired, general malaise,
White powder or paste, lower limb is discharged after the poor yellow-white neoplasm of joint sting, subcutaneous protuberance skin surface and ulceration
The symptoms such as the red and swollen heat pain of distal end single joint and dysfunction.
It is divided into two groups to be treated, wherein one group is control group, one group is observation group, and two groups of cases each 150, two groups sick
Example is at the age, and gender, illness weight etc. is without comparativity.Control group is to Sodium Bicarbonate Tablets, prednisone acetate tablets, pyrrole sieve
Each by specification of former times health piece uses, and 7 as a treatment course, treats the 2-6 course for the treatment of；Observation group's one after each meal embodiment of the present invention 1 is made
The drug obtained, once in the morning and once at night, 7 as a treatment course, treats the 2-6 course for the treatment of.Two groups with cardinal symptom: tired, general malaise,
White powder or paste, lower limb is discharged after the poor yellow-white neoplasm of joint sting, subcutaneous protuberance skin surface and ulceration
The symptoms such as the red and swollen heat pain of distal end single joint and dysfunction mitigation be it is effective, with cardinal symptom: tired, general malaise,
White powder or paste, lower limb is discharged after the poor yellow-white neoplasm of joint sting, subcutaneous protuberance skin surface and ulceration
The symptoms such as the red and swollen heat pain of distal end single joint and dysfunction disappear for recovery from illness.Vertical shelves, which stay to look into, is subject to Statistical Comparison, statistical form
It is bright to the results are shown in Table 1(control group curative effect situation) and table 2(experimental group curative effect situation), by the comparison to control group and experimental group,
The effect of drug therapy gout of the present invention is substantially better than while taking Sodium Bicarbonate Tablets, prednisone acetate tablets, piroxicam tablet
Effect.Medication effect of the present invention: efficient: 91.3%, cure rate 86.7%.
Table 1
Table 2
" typical case ":
1,40 years old, there is tired, general malaise, left knee joint endoprosthesis red and swollen heat pain and dysfunction etc. symptoms 1 year in Cao, male.
It is treated using drug of the present invention, in each 1 time of daily evening in morning, 7 as a treatment course, tired, complete after 2 courses for the treatment of are used in conjunction
The symptoms such as body discomfort, left knee joint endoprosthesis red and swollen heat pain and dysfunction mitigate, after 3 courses for the treatment of, tired, general malaise, left knee
The symptoms such as joint redness and swelling of joints heat pain and dysfunction disappear.It is further continued for taking 1 course for the treatment of day to consolidate curative effect, 2 years nothings of follow-up
Recurrence.
2, Zhao, female, 45 years old, repeatedly tired, general malaise, joint sting, ear subcutaneously swelled what skin surface was belittled
It is discharged after yellow-white neoplasm and ulceration white powder etc. symptoms 2 years.It is treated using drug of the present invention, daily morning
Evening each 1 time, 7 as a treatment course, and after 3 courses for the treatment of are used in conjunction, tired, general malaise, joint sting, ear subcutaneously swell skin surface
The symptoms such as white powder are discharged after poor yellow-white neoplasm and ulceration to mitigate, after 4 courses for the treatment of, tired, general malaise, joint
The disappearance of the symptoms such as white powder is discharged after subcutaneously swelling the poor yellow-white neoplasm of skin surface and ulceration in shouting pain, ear.Again
Continue to take 1 course for the treatment of day to consolidate curative effect, follow-up 2 years without recurrence.
Claims (2)
1. one group for treating the Chinese medicine of gout, it is characterised in that it is made of the raw material of following parts by weight: Radix Angelicae Pubescentis 15-25g, when
Return 6-12g, Radix Astragali 6-12g, Caulis Spatholobi 3-9g, safflower 5-15g, Radix Salviae Miltiorrhizae 3-9g, Radix Notoginseng 5-15g, peach kernel 6-12g, tuber of pinellia 3-9g,
Medicine xiaolingxian 3-9g, turmeric 6-12g, cuttlebone 5-15g, gleditsia sinensis 5-15g, Radix Glycyrrhizae 3-9g.
2. the Chinese medicine for being used to treat gout according to claim 1, it is characterised in that: the parts by weight of each raw material form
For Radix Angelicae Pubescentis 20g, Radix Angelicae Sinensis 9g, Radix Astragali 9g, Caulis Spatholobi 6g, safflower 10g, Radix Salviae Miltiorrhizae 6g, Radix Notoginseng 10g, peach kernel 9g, tuber of pinellia 6g, medicine xiaolingxian
6g, turmeric 9g, cuttlebone 10g, gleditsia sinensis 10g, Radix Glycyrrhizae 6g.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1745839A (en) * | 2004-09-08 | 2006-03-15 | 史钦荣 | Compound Chinese medicine for gout |
| CN101953926A (en) * | 2010-08-25 | 2011-01-26 | 李潇潇 | Oral Chinese medicinal composition for treating gout |
| WO2017101151A1 (en) * | 2015-12-14 | 2017-06-22 | 华坚 | Gout treating traditional chinese medicine composition and preparation method therefor |
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2017
- 2017-08-23 CN CN201710730405.4A patent/CN109420117A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1745839A (en) * | 2004-09-08 | 2006-03-15 | 史钦荣 | Compound Chinese medicine for gout |
| CN101953926A (en) * | 2010-08-25 | 2011-01-26 | 李潇潇 | Oral Chinese medicinal composition for treating gout |
| WO2017101151A1 (en) * | 2015-12-14 | 2017-06-22 | 华坚 | Gout treating traditional chinese medicine composition and preparation method therefor |
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Application publication date: 20190305 |