CN109394625A - Coolant compositions and its manufacture craft - Google Patents
Coolant compositions and its manufacture craft Download PDFInfo
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- CN109394625A CN109394625A CN201811513761.1A CN201811513761A CN109394625A CN 109394625 A CN109394625 A CN 109394625A CN 201811513761 A CN201811513761 A CN 201811513761A CN 109394625 A CN109394625 A CN 109394625A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
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Abstract
The present invention provides a kind of coolant compositions and its manufacture craft, is related to daily necessities field.This coolant compositions, its raw material include: the freshener of 0.8-2 parts by weight, the butanediol of 0.5-2 parts by weight, the auxiliary agent of 0.8-2 parts by weight, the alcohol of 0-10 parts by weight, 0.5-2 parts by weight plant desensitizer, and the water of 90-95 parts by weight, the freshener is selected from least one of menthol and menthyl lactate, and auxiliary agent is selected from least one of emulsifier and rilanit special.It is selected by reasonable raw material proportioning and reasonable raw material, cooling effect is persistently mild, can keep the long period eliminating fatigue, the effect to refresh the mind, while wide application of the crowd.The manufacture craft of coolant compositions, it is easy to operate controllable, effectively improve the stability of freshener.
Description
Technical field
The present invention relates to daily necessities fields, and in particular to a kind of coolant compositions and its manufacture craft.
Background technique
Fatigue is eliminated in order to reach, this purpose to refresh the mind, people come up with many methods, for example drink red ox, drink
The stimulation of the sense of taste classes such as coffee, leaf of having tea, for example the stimulation of the sense of hearings classes such as song is loudly listened, floral water, safflower oil are smeared for another example
Equal haptic stimulus class.There is limitation and range for the stimulation of sense of taste class.Stimulation for sense of hearing class, is easy to produce hearing
Fatigue, to health, there is also adverse effects.For smearing floral water, effect of stimulation is shorter, while the smells such as safflower oil are big,
Smaller scope of application, at the same inventors have found that floral water and safflower oil etc. are irritating, it is not applicable for part population, it is applicable in
Range further reduces.
Accordingly, it is desirable to provide a kind of cooling composition effectively to solve the above problems.
Summary of the invention
The embodiment of the present invention provides a kind of coolant compositions, is selected by reasonable raw material proportioning and reasonable raw material
Effectively solve the above problems.
The embodiment of the present invention provides a kind of manufacture craft of coolant compositions, easy to operate controllable, effectively improves clear
Cool dose of stability.
The present invention solves its technical problem and adopts the following technical solutions to realize.
The embodiment of the present invention proposes that a kind of coolant compositions, raw material include:
The freshener of 0.8-2 parts by weight, the butanediol of 0.5-2 parts by weight, the auxiliary agent of 0.8-2 parts by weight, 0-10 parts by weight
Alcohol, the plant desensitizer of 0.5-2 parts by weight and the water of 90-95 parts by weight.
For example, its raw material includes:
The freshener of 0.8-1.9 parts by weight, the butanediol of 0.6-1.0 parts by weight, the auxiliary agent of 0.8-1.8 parts by weight, 0-9 weight
Measure the alcohol, the plant desensitizer of 0.5-2 parts by weight and the water of 90-95 parts by weight of part.
For example, its raw material includes:
The freshener of 0.8-1.9 parts by weight, the butanediol of 0.6-1.0 parts by weight, 0.9-1.8 parts by weight auxiliary agent, 0.1-9
The water of the alcohol of parts by weight, the plant desensitizer of 0.5-2 parts by weight and 90-95 parts by weight.
Wherein, freshener is selected from least one of menthol and menthyl lactate, and auxiliary agent is selected from emulsifier and hydrogenation castor
At least one of sesame oil.
The coolant compositions provided according to embodiments of the present invention are made by the reasonable cooperation of menthol, menthyl lactate
While cooling effect keeps lasting, stable, mild, prevent menthol stimulation human skin from leading to allergy or discomfort, while several
It has no irritating odor.Moistening effect compared with butanediol and water addition, guarantee coolant compositions human body surface act on
Time is long, further increases the persistence of cooling effect, and plant desensitizer further cooperates with menthyl lactate, prevented
It is quick, while plant desensitizer and menthol cooperate, and carry out inhibiting bacteria and diminishing inflammation, the appropriate addition of alcohol is protected with cooperations such as freshener, water
Whole pure and fresh cooling feeling is held, the scope of application is wider, can keep the long period eliminating fatigue, the effect to refresh the mind.
Specifically, freshener be selected from least one of menthol and menthyl lactate, for example, freshener be menthol,
Or menthyl lactate, or the mixture for menthol and menthyl lactate.Menthol and menthyl lactate as cooling ingredient
The effect of effectively refreshing the mind to human body generation, wherein menthol extracts from natural dried peppermint leaf, not only has refrigerant effect,
Also there are antibacterial and anti-inflammation functions simultaneously, there is certain sterilizing and deodorizing function, while cooling effect is obvious, but menthol is waved
Hair property and irritation are larger, cause cooling effect strong and very brief, meanwhile, it, can be pleasantly sweet peppery with irritation when usage amount is larger
Taste causes the experience of user's comfort level bad, and refrigerant degree is not lasting, and therefore, optionally, freshener includes that menthol and lactic acid are thin
Lotus ester.Wherein, the cooling effect of menthyl lactate is general, strong not as menthol, but the refrigerant effect of menthyl lactate
The persistence of fruit is good, meanwhile, there was only slight peppermint fragrance.
According to some embodiments of the present invention, the weight ratio of above-mentioned menthol and menthyl lactate is 0.4-1:0.4-1, example
Such as, the weight ratio of menthol and menthyl lactate is 1:1,0.4:0.7,0.6:1,1:0.7,0.9:0.5 or 0.8:0.4 etc..It is logical
Reasonable proportion is crossed, while keeping lasting, stable cooling effect, prevents menthol stimulation human skin from leading to allergy or not
It is suitable.
Wherein, optionally, butanediol is 1,3-BDO, and moisturizing safety is good, extends what moisture was stopped in human body surface
Time further extends freshener in the refrigerant stimulation time of human body surface, while also making freshener as the solvent of freshener
The brighter clarification of composition, and then make spray effect more preferably, spraying middle effective component is more uniform.
But butanediol has certain viscosity, therefore, according to some embodiments of the present invention, above-mentioned raw materials further include 0.5-
The erythrite of 1 parts by weight.The moistening effect of erythrite is splendid, while more clear compared to butanediol, without so viscous hand, fits
When addition, while coolant compositions moistening effect can be made good, be sprayed at it is clear after human body surface, it is not sticky, improve
Comfort level and pure and fresh cooling feeling.
The selectivity of emulsifier is added, and can effectively improve stability of the freshener in coolant compositions and uniform
Degree cooperates, better effect with butanediol.According to some embodiments of the present invention, mentioned emulsifier is selected from emulsifier HCO-040,
Freshener can effectively be emulsified.
The selectivity of rilanit special is added, so that the solubility of each ingredient in water is bigger, cooperates with emulsifier etc., has
Effect meets the needs of spraying, and the liquid grain that can satisfy ejection is subtleer, and effective component is more uniform, improves coolant compositions preparation
Thickening degree, while improving the slow release effect of effective component, further enhance the persistence of refrigerant effect, meanwhile, make freshener
After composition is sprayed at human skin, skin is submissive, smoothly, without sticky sense, improves the salubrious degree of skin.
Alcohol can make coolant compositions have the function of certain sterilization and menthol cooperation, and bactericidal effect is good, in turn
Deodorizing effect is good, meanwhile, the addition of alcohol can not only make product because evaporation rate is fast, and next refrigerant with freshener collaboration belt,
And the respiratory ventilation frequency of skin pore can be promoted, so that freshener is easier to penetrate into skin layer, plays and promote refrigerant work
With.But for sensitive, alcohol may also can cause certain sensitization, therefore, those skilled in the art to it
Member can carry out whether alcohol selects to add according to practical situation.Even if adding simultaneously, the content of alcohol is relatively low, this freshener
In combination, the additive amount of alcohol is less than or equal to the 10% of the gross mass of coolant compositions, prevents to generate because of irritation
Quick phenomenon occurs.
Optionally, alcohol is selected from least one of edible alcohol and odorless alcohol, such as alcohol is edible alcohol or nothing
Smelly alcohol, or be edible alcohol and the mixture of odorless alcohol etc., do not do specific restriction herein.
Plant desensitizer, it is on the one hand green safe, on the other hand, by the addition of anti-sensitizer, improve coolant compositions
Safety.
According to some embodiments of the present invention, above-mentioned plant desensitizer includes that mass ratio is followed successively by 0.2-0.7:0.2-1:
Gotu Kola P.E, radix scutellariae root extract, the glycyrrhiza glabra root extract, chamomile of 0.4-1:0.5-1:0.6-1:0.3-0.8
Extract, rosemary leaf extract, Radix et Caulis Opuntiae Dillenii extract.Wherein, Gotu Kola P.E main component is Asiaticoside, centella
Acid and brahmic acid, with multiple efficacies such as antiphlogistic antibacterial, the synthesis of promotion collagen and fibroblastic synthesis；
There is radix scutellariae wider antimicrobial spectrum to have inhibiting effect to a variety of skin pathogenicity fungies, and have anti-inflammatory, antiallergic action to make
With tool anti-allergic effects.The main component of glycyrrhiza glabra root extract is that glycyrrhiza glabra element and glycyrrhiza glabra are fixed, have sterilization,
It releives the function of skin, while there is peat-reek, can reconcile the final tastes of coolant compositions to a certain degree.Ocean is sweet
Chrysanthemum extract mainly contains flavones, soap base, polysaccharide, volatile oil isoreactivity ingredient, and there is anti-inflammatory, inhibition fungi, antiallergy etc. to make
With.Rosemary leaf extract have the effects that it is antibacterial, anti-inflammatory, Radix et Caulis Opuntiae Dillenii extract have antibacterial, anti-inflammatory, antifatigue effect.
Therefore, the rational proportion of above-mentioned 6 kinds of components, can cooperate with freshener, effectively improve the antibiotic and sterilizing effect of coolant compositions
Fruit, while effectively avoiding to freshener allergy, wide application of the crowd, it is safer.
In order to guarantee that coolant compositions have preferable cooling effect, coolant compositions are water based product, wherein water
For purified water, prevent introducing impurity from causing to influence spray effect and cooling effect.
To sum up, by the rational proportion of each component, the stability, persistence and safety of coolant compositions are effectively improved
Property.Coolant compositions bring pure and fresh feel nice and cool with superior sterilization anti-allergic effects, while to people for sensitive skin
Sense, plays the role of arousing brain, raising spirit.
It should be noted that the generation of allergic phenomena in order to prevent, feed components be all necessary for food-grade, pharmaceutical grade or
Person's cosmetics-stage raw material components.
According to some embodiments of the present invention, the dosage form of above-mentioned coolant compositions can be paste, liniment, spray
Deng, in order to keep preferable cooling effect, while preventing from being easy to use, optionally, the dosage form of coolant compositions is spray,
Such as coolant compositions can be packaged as the spray bottle spray of 50ml, 75ml or 100ml etc., and it is easy to carry, it is easy to use.
The embodiment of the present invention proposes a kind of manufacture craft of above-mentioned coolant compositions comprising following steps:
Freshener, butanediol and auxiliary agent are mixed, the first mixed liquor is obtained.
After mixing by water, plant desensitizer, alcohol, the second mixed liquor is obtained.
First mixed liquor is mixed with the second mixed liquor.
The manufacture craft of the coolant compositions provided according to embodiments of the present invention, by step-wise dissolution, mixed mode,
Effectively improve coolant compositions effective component dissolution sufficient degree and mixture homogeneity, stability and quality it is uniform
Property, so that the persistence of the refrigerant degree of product obtained is more stable.
Optionally, when auxiliary agent includes rilanit special and emulsifier, the first mixed liquor is made by following methods: will be refrigerant
Agent, rilanit special and butanediol are mixed to solution clear, and emulsifier is added, and stirring dissolves emulsifier, and it is mixed to obtain first
Close liquid.
Optionally, when auxiliary agent only includes emulsifier, the first mixed liquor is made by following methods: by freshener and butanediol
It mixes to solution clear, emulsifier is added, stirring dissolves emulsifier, obtains the first mixed liquor.
According to some embodiments of the present invention, above-mentioned raw materials further include the erythrite of 0.5-1 parts by weight, the second mixed liquor by
Following methods are made:
After erythrite and water are mixed, plant desensitizer and alcohol are sequentially added.It is planted in the second mixing liquid made
The dispersion of object anti-sensitizer is more uniform, and stability more preferably, while preventing the volatilization of alcohol.
According to some embodiments of the present invention, above-mentioned the step of mixing the first mixed liquor with the second mixed liquor include: with
50-150rmp stirs the second mixed liquor, and during stirring, the first mixed liquor is poured slowly into the second mixed liquor.With 50-150rmp
Stirring rate high-speed stirred, and the step of being poured slowly into are worked in coordination, and the first mixed liquor and the second mixed liquor can be made to mix
It is more uniform, dissolution more preferably, the stability of obtained mixed liquor is more preferably.
According to some embodiments of the present invention, the above-mentioned adding rate being poured slowly into is 10-30ml/min, and adding rate is
Such as 13ml/min, 15ml/min, 18ml/min, 20ml/min, 25ml/min or 26ml/min etc..
Specific embodiment
It in order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below will be in the embodiment of the present invention
Technical solution be clearly and completely described.The person that is not specified actual conditions in embodiment, according to normal conditions or manufacturer builds
The condition of view carries out.Reagents or instruments used without specified manufacturer is the conventional production that can be obtained by commercially available purchase
Product.
The coolant compositions of the embodiment of the present invention and its manufacture craft are specifically described below.
The embodiment of the present invention provides a kind of manufacture craft of above-mentioned coolant compositions comprising following steps:
S1. freshener and butanediol are mixed to solution clear, auxiliary agent is added, is uniformly mixed, it is mixed to obtain first
Close liquid.
S2. after mixing by water, plant desensitizer, alcohol, the second mixed liquor is obtained.
S3. the first mixed liquor is mixed with the second mixed liquor.
Feature and performance of the invention are described in further detail with reference to embodiments.
Embodiment 1
A kind of coolant compositions, raw material include:
Its raw material includes:
The menthol of 0.9 parts by weight, the butanediol of 0.5 parts by weight, the emulsifier HCO-040 of 0.9 parts by weight, 6 parts by weight
Deodorizing alcohol, the plant desensitizer of 1 parts by weight and the purified water of 90.7 parts by weight.
Plant desensitizer includes that mass ratio is followed successively by the Gotu Kola P.E of 0.4:0.5:0.5:0.5:0.6:0.3, radix scutellariae
Root extract, glycyrrhiza glabra root extract, camomile extract, rosemary leaf extract, Radix et Caulis Opuntiae Dillenii extract.
Coolant compositions are made by following technique:
S1. No. 1 emulsion pot, No. 2 emulsion pots are cleaned up in advance, menthol and butanediol is added in No. 1 pot, sufficiently
It stirs evenly, until solution becomes clear, adds emulsifier HCO-040, continue stirring to nodeless mesh, obtain the first mixing
Liquid.
S2. purified water and plant desensitizer are added in No. 2 pots, stirring is eventually adding deodorizing alcohol, uniformly stirs to transparent
It mixes, obtains the second mixed liquor.
S3. the second mixed liquor is stirred with 70rmp, during stirring, by the first mixing in No. 1 pot with the addition of 15ml/min
Rate liquid is slowly added into the second mixed liquor in No. 2 pots, and after mixing, discharging is filling, packaging.
Embodiment 2
A kind of coolant compositions, raw material include:
Its raw material includes:
The menthyl lactate of 0.9 parts by weight, the butanediol of 0.5 parts by weight, the rilanit special of 0.9 parts by weight, 6 parts by weight
Deodorizing alcohol, the plant desensitizer of 1 parts by weight and the purified water of 90.7 parts by weight.
Plant desensitizer includes that mass ratio is followed successively by the Gotu Kola P.E of 0.5:0.5:0.7:0.5:0.6:0.4, radix scutellariae
Root extract, glycyrrhiza glabra root extract, camomile extract, rosemary leaf extract, Radix et Caulis Opuntiae Dillenii extract.
Coolant compositions are made by following technique:
S1. No. 1 emulsion pot, No. 2 emulsion pots are cleaned up in advance, in No. 1 pot be added menthyl lactate, butanediol and
Rilanit special stirs, and until solution becomes clear, obtains the first mixed liquor.
S2. purified water and plant desensitizer are added in No. 2 pots, stirring is eventually adding deodorizing alcohol, uniformly stirs to transparent
It mixes, obtains the second mixed liquor.
S3. the second mixed liquor is stirred with 50rmp, during stirring, by the first mixing in No. 1 pot with the addition of 13ml/min
Rate liquid is slowly added into the second mixed liquor in No. 2 pots, and after mixing, discharging is filling, packaging.
Embodiment 3
A kind of coolant compositions, raw material include:
The menthyl lactate of 0.9 parts by weight, the butanediol of 0.5 parts by weight, the emulsifier HCO-040 of 0.9 parts by weight, 6 weights
Measure the edible alcohol, the plant desensitizer of 1 parts by weight and the purified water of 90.7 parts by weight of part.
Plant desensitizer includes that mass ratio is followed successively by the Gotu Kola P.E of 0.6:0.7:0.6:0.5:0.5:0.7, radix scutellariae
Root extract, glycyrrhiza glabra root extract, camomile extract, rosemary leaf extract, Radix et Caulis Opuntiae Dillenii extract.
Coolant compositions are made by following technique:
S1. No. 1 emulsion pot, No. 2 emulsion pots are cleaned up in advance, menthyl lactate and butanediol are added in No. 1 pot,
It stirs, until solution becomes clear, adds emulsifier HCO-040, continue stirring to nodeless mesh, obtain first
Mixed liquor.
S2. purified water and plant desensitizer are added in No. 2 pots, stirring is eventually adding edible alcohol, uniformly stirs to transparent
It mixes, obtains the second mixed liquor.
S3. the second mixed liquor is stirred with 60rmp, during stirring, by the first mixing in No. 1 pot with the addition of 15ml/min
Rate liquid is slowly added into the second mixed liquor in No. 2 pots, and after mixing, discharging is filling, packaging.
Embodiment 4
A kind of coolant compositions, raw material include:
The menthol of 0.4 parts by weight, the menthyl lactate of 0.5 parts by weight, the butanediol of 0.5 parts by weight, 1 parts by weight cream
Agent HCO-040, the deodorizing alcohol of 5 parts by weight, the erythrite of 0.6 parts by weight, 1.3 parts by weight plant desensitizer, and
The purified water of 90.7 parts by weight.
Plant desensitizer includes that mass ratio is followed successively by the Gotu Kola P.E of 0.6:0.5:0.6:0.5:0.5:0.4, radix scutellariae
Root extract, glycyrrhiza glabra root extract, camomile extract, rosemary leaf extract, Radix et Caulis Opuntiae Dillenii extract.
Coolant compositions are made by following technique:
S1. No. 1 emulsion pot, No. 2 emulsion pots are cleaned up in advance, in No. 1 pot be added menthol, menthyl lactate and
Butanediol stirs, and until solution becomes clear, adds emulsifier HCO-040, continues stirring to no knot
Crystalline substance obtains the first mixed liquor.
S2. purified water and erythrite are added in No. 2 pots, mixing is with rear addition plant desensitizer, and stirring is to transparent, most
After deodorizing alcohol is added, uniform stirring obtains the second mixed liquor.
S3. the second mixed liquor is stirred with 60rmp, during stirring, by the first mixing in No. 1 pot with the addition of 15ml/min
Rate liquid is slowly added into the second mixed liquor in No. 2 pots, and after mixing, discharging is filling, packaging.
Embodiment 5
A kind of coolant compositions, raw material include:
The menthol of 0.4 parts by weight, the menthyl lactate of 0.55 parts by weight, the butanediol of 0.6 parts by weight, 0.9 parts by weight
Emulsifier HCO-040, the deodorizing alcohol of 4 parts by weight, the rilanit special of 0.2 parts by weight, the erythrite of 0.5 parts by weight, 1.2
The purified water of the plant desensitizer of parts by weight and 91.65 parts by weight.
Coolant compositions are made by following technique:
S1. No. 1 emulsion pot, No. 2 emulsion pots are cleaned up in advance, in No. 1 pot be added menthol, menthyl lactate,
Butanediol and rilanit special, stir, and until solution becomes clear, add emulsifier HCO-040, continue
Stirring obtains the first mixed liquor to nodeless mesh.
S2. purified water and erythrite are added in No. 2 pots, mixing is with rear addition plant desensitizer, and stirring is to transparent, most
After deodorizing alcohol is added, uniform stirring obtains the second mixed liquor.
S3. the second mixed liquor is stirred with 60rmp, during stirring, by the first mixing in No. 1 pot with the addition of 15ml/min
Rate liquid is slowly added into the second mixed liquor in No. 2 pots, and after mixing, discharging is filling, packaging.
Embodiment 6
Coolant compositions provided in this embodiment the difference is that only raw material with embodiment 4: its raw material packet
It includes:
The menthol of 0.45 parts by weight, the menthyl lactate of 0.45 parts by weight, the butanediol of 0.5 parts by weight, 0.9 parts by weight
Emulsifier HCO-040, the deodorizing alcohol of 6 parts by weight, the erythrite of 0.5 parts by weight, 1 parts by weight plant desensitizer, and
The purified water of 90.2 parts by weight.
Test example 1
Coolant compositions made from embodiment 6 are tested according to following each standard, the results are shown in Table 1:
1 test result of table
Embodiment 1-5 is tested and assessed according to the method described above, coolant compositions made from embodiment 1-5, which are all satisfied, defends method prison hair
The requirement of (2002) No. 229 files.Coolant compositions made from embodiment 1-5 keep for 24 hours, restoring to room at 40 ± 1 DEG C
Wen Hou, not stratified, coolant compositions made from embodiment 1-5 keep for 24 hours, restoring to after room temperature at 5 ± 1 DEG C, regardless of
Layer, in other words, the coolant compositions good stability that the present invention obtains.
In order to verify whether preparation method have an impact to the stability of freshener, using control group 1 as embodiment 6
Control group, control group 1 the difference is that only with embodiment 6: raw material being mixed together, is stirred with 60rmp to obtained liquid
Body nodeless mesh object.
Control group 1 is tested according to above-mentioned steps progress high temperature, low-temperature stability, as a result, it has been found that, it is protected at 40 ± 1 DEG C
It holds for 24 hours, restores to room temperature, there is slight lamination to generate, after 5 ± 1 DEG C keep for 24 hours, clarity of solution is reduced.It that is to say
It says, the mode of substep mixing really has a certain impact for the stability of coolant compositions.
Test example 2
The coolant compositions for preparing embodiment 1,3,6 are prepared as spray, and the spray that purchase is common in market
Mist floral water (Long Liqi) is bought in the common essential wind oil in market (White Cloud Mountain).
100 20-60 years old subjects are chosen, are arbitrarily divided into 5 groups, wherein three groups are used embodiment 1,3,6 to prepare respectively
Coolant compositions, remaining two groups, respectively using spraying floral water spraying as a control group 2, use essential wind oil as compareing
Group 3.
Through subject feedback, each group is as follows using result:
1. there is more obvious cooling effect, but the duration is shorter when control group 2 sprays, refrigerant sense after average 5-8min
Weaken, while averagely over the course of 15 mins, no refrigerant sense sprays clear water in acting surface again later, and refrigerant sense is faint, but control group
2 have light fragrance, more pleasant, skin refreshing in use process.
2. having obvious cooling effect when control group 3 sprays, the duration is long, and the duration reaches 25-35min, later
Clear water is sprayed again in acting surface, still there is silk silk refrigerant sense, but the taste of control group 3 is larger, part subject does not like, while by
It is strong in refrigerant sense, it is strong for irritations such as eyes, it easily sheds tears, is in green oil, sensory experience in skin surface in use process
It is bad.
3. the cooling effect entry-into-force time of embodiment 1,3,6 is short, the duration is long.Without obvious cooling effect, 1- when sprinkling
Cooling effect is obvious after 2min, and the duration reaches 30-60min, sprays clear water again later in acting surface, still has silk silk refrigerant
Sense.With light salubrious fragrance, wherein the duration of embodiment 3 is better than embodiment 1,6, when the continuous action of embodiment 6
Between be better than embodiment 1, the salubrious degree and cooling effect of embodiment 6 are better than embodiment 3 and embodiment 1.
It finds simultaneously, embodiment 1, embodiment 3, embodiment 6, control group 2 and control group 3 all have certain sterilization and remove
Smelly effect, wherein for fabrics, control group 3 is not applicable, and 6 effect of embodiment is obvious, embodiment 1, embodiment 3 and comparison
The effect object significant difference of example 3.
In use process, the antiallergic effect of the sensitive flesh subject feedback in part, coolant compositions provided by the invention are bright
It is aobvious.Good effect can be played for the treatment of the antiallergic of sensitive skin, anti-anaphylaxis and steroid dependent dermatitis, had good
The effect of repairing skin barrier.
To sum up, the coolant compositions of the offer of the embodiment of the present invention pass through reasonable raw material proportioning and reasonable original
Material, refrigerant sense is lasting, fragrant and salubrious, can be used for sensitive flesh and uses, wide using crowd, while the offer of the embodiment of the present invention is clear
The manufacture craft of cool dose of composition, it is easy to operate controllable, effectively improve the stability of freshener.
Embodiments described above is a part of the embodiment of the present invention, instead of all the embodiments.Reality of the invention
The detailed description for applying example is not intended to limit the range of claimed invention, but is merely representative of selected implementation of the invention
Example.Based on the embodiments of the present invention, obtained by those of ordinary skill in the art without making creative efforts
Every other embodiment, shall fall within the protection scope of the present invention.
Claims (10)
1. a kind of coolant compositions, which is characterized in that its raw material includes:
The freshener of 0.8-2 parts by weight, the butanediol of 0.5-2 parts by weight, the auxiliary agent of 0.8-2 parts by weight, 0-10 parts by weight wine
The water of essence, the plant desensitizer of 0.5-2 parts by weight and 90-95 parts by weight；
Wherein, the freshener is selected from least one of menthol and menthyl lactate；
The auxiliary agent is selected from least one of emulsifier and rilanit special.
2. coolant compositions according to claim 1, which is characterized in that the freshener includes the menthol and institute
State menthyl lactate, the weight ratio of the menthol and the menthyl lactate is 0.4-1:0.4-1.
3. coolant compositions according to claim 1, which is characterized in that the raw material further includes 0.5-1 parts by weight
Erythrite.
4. coolant compositions according to claim 1, which is characterized in that the plant desensitizer include mass ratio successively
Gotu Kola P.E, radix scutellariae root extract, glycyrrhiza glabra for 0.2-0.7:0.2-1:0.4-1:0.5-1:0.6-1:0.3-0.8
Root extract, camomile extract, rosemary leaf extract, Radix et Caulis Opuntiae Dillenii extract.
5. coolant compositions according to claim 1, which is characterized in that the emulsifier is selected from emulsifier HCO-040.
6. coolant compositions according to claim 1, which is characterized in that the dosage form of the coolant compositions is spraying
Agent.
7. a kind of manufacture craft of coolant compositions as described in claim 1, which comprises the steps of:
The freshener, the butanediol, the auxiliary agent are mixed, the first mixed liquor is obtained；
After mixing by the water, the plant desensitizer, the alcohol, the second mixed liquor is obtained；
First mixed liquor is mixed with second mixed liquor.
8. manufacture craft according to claim 7, which is characterized in that the raw material further includes the red moss of 0.5-1 parts by weight
Alcohol, second mixed liquor are made by following methods:
After the erythrite and the water are mixed, the plant desensitizer and the alcohol are sequentially added.
9. manufacture craft according to claim 7, which is characterized in that by first mixed liquor and second mixed liquor
The step of mixing includes: to stir second mixed liquor with 50-150rmp, and during stirring, first mixed liquor is slowly fallen
Enter in second mixed liquor.
10. manufacture craft according to claim 9, which is characterized in that the adding rate being poured slowly into is 10-
30ml/min。
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| CN201811513761.1A CN109394625A (en) | 2018-12-11 | 2018-12-11 | Coolant compositions and its manufacture craft |
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| CN201811513761.1A CN109394625A (en) | 2018-12-11 | 2018-12-11 | Coolant compositions and its manufacture craft |
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| CN111821231A (en) * | 2020-06-19 | 2020-10-27 | 广州艾蓓生物科技有限公司 | Refreshing composition and preparation method thereof |
| CN114182526A (en) * | 2021-12-27 | 2022-03-15 | 广东好顺欧迪斯科技股份有限公司 | Clothing cooling spray and preparation method thereof |
| CN114681361A (en) * | 2022-04-02 | 2022-07-01 | 厦门金泰生物科技有限公司 | Ice-cold compound liquid and preparation method thereof |
| CN115089503A (en) * | 2022-07-19 | 2022-09-23 | 吴成林 | Water-soluble cool agent and preparation method thereof |
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| CN115089503A (en) * | 2022-07-19 | 2022-09-23 | 吴成林 | Water-soluble cool agent and preparation method thereof |
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