CN109394268A - Polyp extent of injury Mapping Platform - Google Patents

Polyp extent of injury Mapping Platform Download PDF

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Publication number
CN109394268A
CN109394268A CN201811493264.XA CN201811493264A CN109394268A CN 109394268 A CN109394268 A CN 109394268A CN 201811493264 A CN201811493264 A CN 201811493264A CN 109394268 A CN109394268 A CN 109394268A
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polyp
image
equipment
injury
extent
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CN109394268B (en
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朱桥波
陈姗姗
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Yuyao Huayao Tool Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
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Abstract

The present invention relates to a kind of polyp extent of injury Mapping Platforms, comprising: A/D converter is used for receives echo-signal, and echo-signal is analog signal, carries out A/D transformation to echo-signal to be quantized into 16 digital signals;Line memory bank is connect with A/D converter, realizes the rest and reorganization of 16 digital signals for receiving 16 digital signals, and in on-line storage body to complete the composition of the composite ultraphonic scanning beam of four focuses;Frame memory is connect with line memory bank, and the data for exporting line memory bank store;Form discrimination equipment, for being detected based on polyp imaging features to the polyp target in virtual color display image, to obtain corresponding polyp subgraph;Discriminating device is endangered, is analyzed for the radical length to polyp subgraph, to determine the extent of injury being proportional based on radical length and be exported as the polyp extent of injury.By means of the invention it is possible to directly judge the extent of injury of polyp.

Description

Polyp extent of injury Mapping Platform
Technical field
The present invention relates to B ultrasound to shine shadow field more particularly to a kind of polyp extent of injury Mapping Platform.
Background technique
B ultrasound shines shadow equipment principle: contrast agent micro bubbles can vibrate under the action of ultrasound, scatter strong ultrasonic signal. This is also the most important characteristic of acoustic contrast agent --- enhancing backscatter signals.Such as in B ultrasound, by being infused into blood vessel Enter acoustic contrast agent, available very strong B ultrasound echo, thus clearer display vessel position and size on the image.
The ultrasound intensity received is the function of the scattering section of incident intensity and reflector.Scattering section is and frequency Six powers of biquadratic and scatterer radius are directly proportional, this is all suitable for all contrast mediums.Theoretically, by simple It calculates it is seen that the scattering section of bubble particle is 100,000,000 times bigger than an equal amount of solids.This is also bubble composition Contrast agent shine shadow effect reason for it more superior than other scatterer.
Summary of the invention
In order to solve the technical issues of B ultrasound can not directly judge the polyp extent of injury according to shadow equipment in the prior art, this hair It is bright to provide a kind of polyp extent of injury Mapping Platform.
The present invention at least has following three important inventive points: (1) carrying out targetedly image procossing according to shadow figure to B ultrasound Afterwards, it introduces form discrimination equipment and obtains corresponding polyp subgraph, introducing endangers discriminating device to the diameter of the polyp subgraph It is analyzed to length, to determine the extent of injury being proportional based on radical length and be exported as the polyp extent of injury; (2) the parsing operation of gray value mean value is carried out to real-time sharpening image, wherein particular, it is important that the picture based on real-time sharpening image The parsing of vegetarian refreshments gray value progress gray value mean value;(3) in the case where gray value mean value backlog demand, increased using pseudo-colours Strong equipment executes the processing of frequency domain virtual color display to the real-time sharpening image and is increased with obtaining gray value mean value pseudo-colours up to standard Strong image.
According to an aspect of the present invention, a kind of polyp extent of injury Mapping Platform is provided, the platform includes:
A/D converter is used for receives echo-signal, and the echo-signal is analog signal, carries out to the echo-signal A/D is converted to be quantized into 16 digital signals;Line memory bank is connect with the A/D converter, for receiving described 16 Digital signal, and the rest and reorganization of the digital signal of realization 16 are swept in the line memory bank with the composite ultraphonic for completing four focuses Retouch the composition of wave beam;Frame memory is connect with the line memory bank, and the data for exporting the line memory bank are deposited Storage;Image sharpening equipment is connect with the frame memory, for receiving the picture frame of the frame memory output, to the figure It is handled as frame executes image sharpening, to obtain corresponding real-time sharpening image;Mean value analyzing device enhances equipment with the edge Connection executes the parsing operation of gray value mean value to the real-time sharpening image, to obtain for receiving the real-time sharpening image The gray value mean value of the real-time sharpening image as reference gray level value mean value to export;It is right in the mean value analyzing device The real-time sharpening image executes the parsing operation of gray value mean value, to obtain the gray value mean value of the real-time sharpening image to make It include: each gray value for obtaining each pixel in the real-time sharpening image for the output of reference gray level value mean value, it will be described The arithmetic mean of instantaneous value of each gray value is exported as the reference gray level value mean value;Parameter compares equipment, parses with the mean value Equipment connection, for receiving the reference gray level value mean value, and by the reference gray level value mean value and gray value mean value threshold value into Row compares, to issue first and compare instruction when the reference gray level value mean value is more than or equal to the gray value mean value threshold value, When the reference gray level value mean value is less than the gray value mean value threshold value, issues second and compare instruction;Virtual color display equipment, point Equipment is not compared with the parameter and the mean value analyzing device is connect, for receive it is described second compare instruction when, it is right The real-time sharpening image executes the processing of frequency domain virtual color display, to obtain virtual color display image, is also used to receiving When stating the first control instruction, exported the real-time sharpening image as virtual color display image;Form discrimination equipment, and it is described Virtual color display image connection, for being examined based on polyp imaging features to the polyp target in the virtual color display image It surveys, to obtain corresponding polyp subgraph;Discriminating device is endangered, is connect with the form discrimination equipment, for the polyp The radical length of subgraph is analyzed, to determine the extent of injury being proportional based on radical length and endanger as polyp Degree output.
More specifically, in the polyp extent of injury Mapping Platform: being also built-in with RAM in the parameter comparison equipment Unit, for storing the gray value mean value threshold value.
More specifically, in the polyp extent of injury Mapping Platform: the virtual color display equipment is by digital processing core Piece realizes using the Harvard structure that program and data are separated inside the digital processing chip, have hardware multiplier, use Pile line operation provides various digital processing control instructions to realize various digital signal processing algorithms respectively.
More specifically, in the polyp extent of injury Mapping Platform, further includes:
Lines extract equipment is connect with the frame memory, for receiving the picture frame of the frame memory output, from institute It states and extracts a plurality of contour line in picture frame, and export a plurality of contour line, each contour line is composition described image frame In some target lines.
More specifically, in the polyp extent of injury Mapping Platform, further includes:
Variation identification equipment, connect, for receiving a plurality of contour line, for each with the lines extract equipment Contour line executes following movement: determine the profile curvature of a curve, and when the profile curvature of a curve is more than predetermined curvature value, It is exported the contour line as effective contour line.
More specifically, in the polyp extent of injury Mapping Platform, further includes:
Lines unit equipment is connect with variation identification equipment, for receiving the more of the variation identification equipment output Bar effective contour line, using the image block surrounded in described image frame by effective contour line as effective image block, and exports institute State each effective image block in picture frame.
More specifically, in the polyp extent of injury Mapping Platform, further includes:
Field processing equipment is connect with the lines unit equipment, for receiving each described effective image block, to institute It states each effective image block and executes image enhancement processing, to obtain in-situ processing image block, and export each in-situ processing figure As block.
More specifically, in the polyp extent of injury Mapping Platform, further includes:
Data lifting means sharpens equipment with described image respectively and the field processing equipment is connect, for receiving Each in-situ processing image block is stated, and degree of comparing promotion is handled respectively to each in-situ processing image block, to obtain Each data promote image block, and each data promotion image block is integrally replaced described image frame and is sent to described image Sharpen equipment.
More specifically, in the polyp extent of injury Mapping Platform: the lines unit equipment by lines receiving unit, Image recognition unit and image block output unit composition;Wherein, the lines receiving unit is for receiving the variation identification The a plurality of effective contour line of equipment output, described image block output unit are used to export each effective image in described image frame Block.
More specifically, in the polyp extent of injury Mapping Platform: described image block recognition unit respectively with the line Receiving unit is connected with described image block output unit, the image for will be surrounded in described image frame by effective contour line Block is as effective image block;Wherein, in variation identification equipment, predetermined curvature value is less than in the profile curvature of a curve When, using the contour line as null contour line;Wherein, the data lifting means is to each in-situ processing image block point The contrast promotion processing not carried out is parallel processing mode.
Detailed description of the invention
Embodiment of the present invention is described below with reference to attached drawing, in which:
Fig. 1 is the operative scenario figure according to the polyp extent of injury Mapping Platform shown in embodiment of the present invention.
Specific embodiment
The embodiment of polyp extent of injury Mapping Platform of the invention is described in detail below with reference to accompanying drawings.
B ultrasound contrast apparatus using it is more be the occupational diseases such as liver, kidney, pancreas, thyroid gland diagnosis and check, Wherein the clinical application in terms of liver is the most successful.(1) liver neoplasm or lesion are benign with pernicious identification, including liver cancer (primary carcinoma of liver, metastatic tumor), hemangioma, adenoma, focal nodular hyperplasia non-uniform Distribution fatty liver etc. identify;(2) liver cancer Preoperative routine hepatic ultrasound contrast enhancement, further determines that the size of tumour and invades range, whether there is or not transfer stoves small in hidden liver Or multifocal tumour;(3) application in liver tumour invasive diagnosis: ultrasonic contrast facilitates special to minimal neoplastic suspicious in liver It is not the localised puncture biopsy of equal echo tubercle;(4) application in liver tumour interventional therapy: can be after transcatheter hepatic arterial chemoembolization Ultrasound shines shadow, can also after radio frequency, microwave ablation, high-strength focusing ultrasonic therapy ultrasonic contrast by bed immediately, judge that ablation is controlled Therapeutic effect and there is noresidue tumor tissue, to determine to be further processed, improves curative effect.For can be with without the patient that is further processed Carry out long term follow-up;(5) application of the ultrasound according to shadow in operation of liver cancer: it is reported that shone in art shadow can detect/except other are smaller Tumour, change surgery process range or approach in time.
In order to overcome above-mentioned deficiency, the present invention has built a kind of polyp extent of injury Mapping Platform, can effectively solve the problem that phase The technical issues of answering.
Fig. 1 is the operative scenario figure according to the polyp extent of injury Mapping Platform shown in embodiment of the present invention, wherein 1 It is control equipment for Ultrasonic-B probe, 2,3 is show equipment, and 4 be polyp detection human body, and the platform includes:
A/D converter is used for receives echo-signal, and the echo-signal is analog signal, carries out to the echo-signal A/D is converted to be quantized into 16 digital signals;
Line memory bank is connect with the A/D converter, is deposited for receiving 16 digital signals, and in the line Chu Tizhong realizes the rest and reorganization of 16 digital signals to complete the composition of the composite ultraphonic scanning beam of four focuses;
Frame memory is connect with the line memory bank, and the data for exporting the line memory bank store;
Image sharpening equipment is connect with the frame memory, for receiving the picture frame of the frame memory output, to institute It states picture frame and executes image sharpening processing, to obtain corresponding real-time sharpening image;
Mean value analyzing device is connect, for receiving the real-time sharpening image, to the reality with edge enhancing equipment When sharpening image execute the parsing operation of gray value mean value, to obtain the gray value mean value of the real-time sharpening image using as reference The output of gray value mean value;
In the mean value analyzing device, the parsing operation of gray value mean value is executed to the real-time sharpening image, to obtain The gray value mean value of the real-time sharpening image is to include: to obtain the real-time sharpening image as the output of reference gray level value mean value In each pixel each gray value, the arithmetic mean of instantaneous value of each gray value is defeated as the reference gray level value mean value Out;
Parameter compares equipment, connect with the mean value analyzing device, for receiving the reference gray level value mean value, and by institute It states reference gray level value mean value to be compared with gray value mean value threshold value, to be more than or equal to the ash in the reference gray level value mean value When angle value mean value threshold value, issues first and compare instruction, when the reference gray level value mean value is less than the gray value mean value threshold value, It issues second and compares instruction;
Virtual color display equipment, compares equipment with the parameter respectively and the mean value analyzing device is connect, for connecing When receiving the second comparison instruction, the processing of frequency domain virtual color display is executed to the real-time sharpening image, to obtain pseudo-colours Enhance image, is also used to when receiving first control instruction, using the real-time sharpening image as virtual color display figure As output;
Form discrimination equipment is connect with the virtual color display image, for color to the puppet based on polyp imaging features Polyp target in color enhancing image is detected, to obtain corresponding polyp subgraph;
Endanger discriminating device, connect with the form discrimination equipment, for the radical length to the polyp subgraph into Row analysis, to determine the extent of injury being proportional based on radical length and be exported as the polyp extent of injury.
Then, continue that the specific structure of polyp extent of injury Mapping Platform of the invention is further detailed.
In the polyp extent of injury Mapping Platform: being also built-in with ram cell in the parameter comparison equipment, be used for Store the gray value mean value threshold value.
In the polyp extent of injury Mapping Platform: the virtual color display equipment realized by digital processing chip, Using the Harvard structure that program and data are separated inside the digital processing chip, there is hardware multiplier, grasped using assembly line Make, provides various digital processing control instructions to realize various digital signal processing algorithms respectively.
In the polyp extent of injury Mapping Platform, further includes:
Lines extract equipment is connect with the frame memory, for receiving the picture frame of the frame memory output, from institute It states and extracts a plurality of contour line in picture frame, and export a plurality of contour line, each contour line is composition described image frame In some target lines.
In the polyp extent of injury Mapping Platform, further includes:
Variation identification equipment, connect, for receiving a plurality of contour line, for each with the lines extract equipment Contour line executes following movement: determine the profile curvature of a curve, and when the profile curvature of a curve is more than predetermined curvature value, It is exported the contour line as effective contour line.
In the polyp extent of injury Mapping Platform, further includes:
Lines unit equipment is connect with variation identification equipment, for receiving the more of the variation identification equipment output Bar effective contour line, using the image block surrounded in described image frame by effective contour line as effective image block, and exports institute State each effective image block in picture frame.
In the polyp extent of injury Mapping Platform, further includes:
Field processing equipment is connect with the lines unit equipment, for receiving each described effective image block, to institute It states each effective image block and executes image enhancement processing, to obtain in-situ processing image block, and export each in-situ processing figure As block.
In the polyp extent of injury Mapping Platform, further includes:
Data lifting means sharpens equipment with described image respectively and the field processing equipment is connect, for receiving Each in-situ processing image block is stated, and degree of comparing promotion is handled respectively to each in-situ processing image block, to obtain Each data promote image block, and each data promotion image block is integrally replaced described image frame and is sent to described image Sharpen equipment.
In the polyp extent of injury Mapping Platform: the lines unit equipment is known by lines receiving unit, image block Other unit and image block output unit composition;
Wherein, the lines receiving unit is used to receive a plurality of effective contour line of the variation identification equipment output, institute Image block output unit is stated for exporting each effective image block in described image frame.
In the polyp extent of injury Mapping Platform: described image block recognition unit respectively with the lines receiving unit It is connected with described image block output unit, the image block for will be surrounded in described image frame by effective contour line is as effectively Image block;
It wherein,, will be described when the profile curvature of a curve is less than predetermined curvature value in variation identification equipment Contour line is as null contour line;
Wherein, the data lifting means handles the contrast promotion that each in-situ processing image block carries out respectively It is parallel processing mode.
In addition, the variation identification equipment is realized by MCU controller.MCU can be divided into no piece by its type of memory Two kinds of ROM type in ROM type and strap.For the chip of ROM type in no piece, it is necessary to which external EPROM could be using (typical chip is 8031).The chip of ROM type is divided into EPROM type (typical chip 87C51) in piece, mask rom type in MASK piece again in strap The types such as (typical chip 8051), in-chip FLASH type (typical chip 89C51), some companies also release in piece one The chip (typical chip 97C51) of secondary property programming ROM (One Time Programming, OTP).The MCU valence of MASKROM Lattice are cheap, but program has been cured when leaving the factory, are suitble to the changeless application of program;The MCU program of FLASH ROM can With repeatedly erasable, flexibility is very strong, but price is higher, is suitble to the application insensitive to price or does exploitation purposes; The MCU price of OTPROM possesses One Time Programmable ability between the above two again, is suitble to both require natural living Property, and the electronic product that rapid volume production was constantly updated, needed in the application of requirement low cost, especially function.
Using polyp extent of injury Mapping Platform of the invention, can not directly sentence for B ultrasound in the prior art according to shadow equipment The technical issues of disconnected polyp extent of injury, introduces form discrimination and sets after carrying out targetedly image procossing according to shadow figure to B ultrasound Standby to obtain corresponding polyp subgraph, introducing endangers discriminating device and analyzes the radical length of the polyp subgraph, with The extent of injury being proportional is determined based on radical length and is exported as the polyp extent of injury;Real-time sharpening image is carried out Gray value mean value parsing operation, wherein particular, it is important that the pixel gray value based on real-time sharpening image carries out gray value The parsing of mean value;In the case where gray value mean value backlog demand, the real-time sharpening is schemed using virtual color display equipment As executing the processing of frequency domain virtual color display to obtain gray value mean value virtual color display image up to standard;To solve above-mentioned skill Art problem.
It is understood that although the present invention has been disclosed in the preferred embodiments as above, above-described embodiment not to Limit the present invention.For any person skilled in the art, without departing from the scope of the technical proposal of the invention, Many possible changes and modifications all are made to technical solution of the present invention using the technology contents of the disclosure above, or are revised as With the equivalent embodiment of variation.Therefore, anything that does not depart from the technical scheme of the invention are right according to the technical essence of the invention Any simple modifications, equivalents, and modifications made for any of the above embodiments still fall within the range of technical solution of the present invention protection It is interior.

Claims (10)

1. a kind of polyp extent of injury Mapping Platform, the platform include:
A/D converter is used for receives echo-signal, and the echo-signal is analog signal, carries out A/D change to the echo-signal It changes to be quantized into 16 digital signals;
Line memory bank is connect with the A/D converter, for receiving 16 digital signals, and in the line memory bank The rest and reorganization of the middle digital signal for realizing 16 are to complete the composition of the composite ultraphonic scanning beam of four focuses;
Frame memory is connect with the line memory bank, and the data for exporting the line memory bank store;
Image sharpening equipment is connect with the frame memory, for receiving the picture frame of the frame memory output, to the figure It is handled as frame executes image sharpening, to obtain corresponding real-time sharpening image;
Mean value analyzing device is connect with edge enhancing equipment, for receiving the real-time sharpening image, to described sharp in real time Change image and execute the parsing operation of gray value mean value, to obtain the gray value mean value of the real-time sharpening image using as reference gray level It is worth mean value output;
In the mean value analyzing device, the parsing operation of gray value mean value is executed to the real-time sharpening image, described in obtaining The gray value mean value of real-time sharpening image is to include: to obtain in the real-time sharpening image respectively as the output of reference gray level value mean value Each gray value of a pixel is exported the arithmetic mean of instantaneous value of each gray value as the reference gray level value mean value;
Parameter compares equipment, connect with the mean value analyzing device, for receiving the reference gray level value mean value, and by the ginseng It examines gray value mean value to be compared with gray value mean value threshold value, to be more than or equal to the gray value in the reference gray level value mean value It when mean value threshold value, issues first and compares instruction, when the reference gray level value mean value is less than the gray value mean value threshold value, issue Second compares instruction;
Virtual color display equipment, compares equipment with the parameter respectively and the mean value analyzing device is connect, for receiving When the second comparison instruction, the processing of frequency domain virtual color display is executed to the real-time sharpening image, to obtain virtual color display Image is also used to when receiving first control instruction, and the real-time sharpening image is defeated as virtual color display image Out;
Form discrimination equipment is connect with the virtual color display image, for being increased based on polyp imaging features to the pseudo-colours Polyp target in strong image is detected, to obtain corresponding polyp subgraph;
Discriminating device is endangered, is connect with the form discrimination equipment, is divided for the radical length to the polyp subgraph Analysis, to determine the extent of injury being proportional based on radical length and be exported as the polyp extent of injury.
2. polyp extent of injury Mapping Platform as described in claim 1, it is characterised in that:
It is also built-in with ram cell in the parameter comparison equipment, for storing the gray value mean value threshold value.
3. polyp extent of injury Mapping Platform as claimed in claim 2, it is characterised in that:
The virtual color display equipment is realized by digital processing chip, and program and data are used inside the digital processing chip Separated Harvard structure has hardware multiplier, using pile line operation, provides various digital processing control instructions with real respectively Existing various digital signal processing algorithms.
4. polyp extent of injury Mapping Platform as claimed in claim 3, which is characterized in that the platform further include:
Lines extract equipment is connect with the frame memory, for receiving the picture frame of the frame memory output, from the figure As extracting a plurality of contour line in frame, and a plurality of contour line is exported, each contour line is certain in composition described image frame The lines of one target.
5. polyp extent of injury Mapping Platform as claimed in claim 4, which is characterized in that the platform further include:
Variation identification equipment, connect, for receiving a plurality of contour line, for each profile with the lines extract equipment Line executes following movement: the profile curvature of a curve is determined, and when the profile curvature of a curve is more than predetermined curvature value, by institute Contour line is stated to export as effective contour line.
6. polyp extent of injury Mapping Platform as claimed in claim 5, which is characterized in that the platform further include:
Lines unit equipment is connect with variation identification equipment, for receiving a plurality of the having of the variation identification equipment output Contour line is imitated, using the image block surrounded in described image frame by effective contour line as effective image block, and exports the figure As each effective image block in frame.
7. polyp extent of injury Mapping Platform as claimed in claim 6, which is characterized in that the platform further include:
Field processing equipment is connect with the lines unit equipment, for receiving each described effective image block, to described every One effective image block executes image enhancement processing, to obtain in-situ processing image block, and exports each in-situ processing image block.
8. polyp extent of injury Mapping Platform as claimed in claim 7, which is characterized in that the platform further include:
Data lifting means sharpens equipment with described image respectively and the field processing equipment is connect, described each for receiving A in-situ processing image block, and degree of comparing promotion is handled respectively to each in-situ processing image block, it is each to obtain Data promote image block, and each data promotion image block is integrally replaced described image frame and is sent to described image sharpening Equipment.
9. polyp extent of injury Mapping Platform as claimed in claim 8, it is characterised in that:
The lines unit equipment is made of lines receiving unit, image recognition unit and image block output unit;
Wherein, the lines receiving unit is used to receive a plurality of effective contour line of the variation identification equipment output, the figure As block output unit is used to export each effective image block in described image frame.
10. polyp extent of injury Mapping Platform as claimed in claim 9, it is characterised in that:
Described image block recognition unit is connect with the lines receiving unit and described image block output unit respectively, for will be The image block surrounded in described image frame by effective contour line is as effective image block;
Wherein, in variation identification equipment, when the profile curvature of a curve is less than predetermined curvature value, by the profile Line is as null contour line;
Wherein, the contrast promotion processing that the data lifting means carries out each in-situ processing image block respectively is simultaneously Row tupe.
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