CN109363980A - A kind of antibacterial mouthwash - Google Patents
A kind of antibacterial mouthwash Download PDFInfo
- Publication number
- CN109363980A CN109363980A CN201810940606.1A CN201810940606A CN109363980A CN 109363980 A CN109363980 A CN 109363980A CN 201810940606 A CN201810940606 A CN 201810940606A CN 109363980 A CN109363980 A CN 109363980A
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- CN
- China
- Prior art keywords
- extract liquor
- test
- peppermint
- xylitol
- antibacterial
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention provides a kind of antibacterial mouthwash, and raw material includes: deionized water, honeysuckle extract liquor, Cortex Magnoliae Officinalis extract liquor, catechin, left hand perfume, citric acid, xylitol, peppermint, tea extraction liquid, licorice extract, benzoic acid；This product is extracted by pure natural herbaceous material, mouthfeel is mild, and faint scent is slightly sweet, nonirritant, easily it is esthetically acceptable to the consumers, the not chemical substances such as spirituosity, hydrogen peroxide, metronidazole, Tinidazole, health is without side-effects, and antibacterial effect is prominent, facilitate full oral cleaning, prevent implication, the formation of gum problem and plaque, persistent.
Description
Technical field
The present invention relates to daily chemical product fields, more particularly to a kind of antibacterial mouthwash.
Background technique
Many diseases are, especially various pathogenic bacteria, such as staphylococcus aureus, green pus bar unhygienic caused by oral cavity
Bacterium, hemolytic streptococcus etc., caused common frdquently encountered disease directly affect people's health, therefore, oral hygiene increasingly by
Pay attention to, only by the cleaning of toothpaste toothbrush, though certain cleaning action can be played, but part is difficult to clean, many bacterium colonies cannot
It eliminates thoroughly, breeds a large amount of bacteriums again in the short time, in order to improve cleaning effect, all kinds of mouthwashes come into being, in order to improve
Bactericidal effect, many mouthwashes are separately added into the chemical substances such as alcohol, hydrogen peroxide, metronidazole, Tinidazole, but to oral cavity irritation
Larger, generation accidentally gulps down situation to body nocuousness, though some mouthwash irritations using the coptis, Radix Ophiopogonis, red sage root extract are small, is good for
Health is harmless, but itself bitter mouthfeel is poor, it is not easy to be received by the majority of consumers.
Summary of the invention
The purpose of the present invention is to provide a kind of pure natural draft to extract, and mild non-stimulated, safety is without side-effects, and mouthfeel is all
Good antibacterial mouthwash.
To achieve the above object, the present invention provide product formula are as follows: deionized water, honeysuckle extract liquor, Cortex Magnoliae Officinalis extract liquor,
Catechin, left hand perfume, citric acid, xylitol, peppermint, tea extraction liquid, licorice extract, benzoic acid.
Preferably, in a kind of above-mentioned antibacterial mouthwash, the raw material proportioning are as follows: deionized water 88.732%, honeysuckle
Extract liquor 3%, Cortex Magnoliae Officinalis extract liquor 2.5%, catechin 2.5%, left hand perfume (or spice) 2%, citric acid 0.002%, xylitol 0.15%, peppermint
0.008%, tea extraction liquid 0.5%, licorice extract 0.6%, benzoic acid 0.08%.
It can be seen via above technical scheme that compared with prior art, all pure natural herbaceous materials of raw material of the present invention
Extraction, mouthfeel is mild, nonirritant, and xylitol and peppermint is added, and improves mouthfeel, faint scent is slightly sweet, is easily esthetically acceptable to the consumers, and is free of
The chemical substances such as alcohol, hydrogen peroxide, metronidazole, Tinidazole, health is without side-effects, micro accidentally to gulp down harmless to the body, antibacterial effect
It is prominent, facilitate full oral cleaning, prevents implication, the formation of gum problem and plaque, persistent.
Specific embodiment
The embodiment of the present invention provide a kind of antibacterial mouthwash formula and proportion it is as follows:
(deionized water 88.732%, honeysuckle extract liquor 3%, Cortex Magnoliae Officinalis extract liquor 2.5%, catechin 2.5%, left hand perfume (or spice) 2%, citric acid
0.002%, xylitol 0.15%, peppermint 0.008%, tea extraction liquid 0.5%, licorice extract 0.6%, benzoic acid 0.08%.
Examining report data and effect:
Examining report 1: acute eye irritation/corrosivity
The method of inspection: " disinfection technology standard " 2002 editions, Part III 2.3.4
Test procedure: it before test for 24 hours, carries out routine examination to two eyes of experimental animal.When test, experiment is gently pulled open
The palpebra inferior of animal side eyes instills given the test agent 0.1ml in conjunctival sac, and eye is passively closed 4s, tested to prevent
Sample is lost, and pure water rinsing, sufficiently removal residual are used after 30s.Other side eyes are as own control.After eye drip 1h,
For 24 hours, 48h, 72h, 7d, 14d and 21d check eyes, check cornea and rainbow with 2% Fluress when necessary
The variation of film.
Test result:
Conclusion: under this experimental condition, tested material eye irritation/corrosion test result acute to new zealand rabbit is stingless
Swash property.
Examining report 2: Suspension quantitative bactericidal test, the test of neutralizer suspension Quantitative measurement
The method of inspection: the preparation of bacteria suspension: quantitative according to " disinfection technology standard " (version in 2002) 2.1.1.5 neutralizer suspension
Qualification test, choosing bacteria containing amount is 1 × 108Cfu/mL~5 × 108The bacteria suspension neutralizer qualification test of cfu/mL；
According to " disinfection technology standard " (version in 2002) 2.1.1.7 bacteria quantified sterilization test, choose bacteria containing amount be 1 ×
108Cfu/mL~5 × 108The bacteria suspension of cfu/mL carries out bacteria quantified sterilization test；
Detection method: referring to " disinfection technology standard " (version in 2002) 2.1.1.7 bacteria quantified sterilization test, test specimen is used
Stoste, action time 20s, test are repeated 3 times.
Neutralizer :+0.85% sodium chloride of+0.5%+0.5% peptone of sodium thiosulfate+0.5%L- histidine of 3% Tween-80+
+ 0.1% cysteine of 1.43% lecithin.
Test condition: temperature: 22.3 DEG C, humidity: 61 DEG C.
Testing result:
Conclusion:
Suspension quantitative bactericidal test test specimen stoste, action time 20s, test is repeated 3 times, to staphylococcus aureus
The killing logarithm of (ATCC 6538), Escherichia coli (8099) >=5.00, meets " disinfection technology standard " version-in 2002
2.1.1.7.7 defined standard value.
Examining report 3: total number of bacterial colonies, fungus colony sum, coliform, staphylococcus aureus, Pseudomonas aeruginosa,
Hemolytic streptococcus, bacteriostasis property, stripping property bacteriostatic test.
Detection method: detection foundation: GB 15979-2002 " Disposable Sanitary Accessory sanitary standard " Appendix B.
Testing conditions: 22.3 DEG C of environment temperature, relative humidity 61%.
Testing result:
| Testing index | Standard value | Measured value |
| Total number of bacterial colonies (cfu/g) | ≤200 | < 20 |
| Fungus colony sum (cfu/g) | ≤100 | < 20 |
| Coliform | It must not detect | It is not detected |
| Staphylococcus aureus | It must not detect | It is not detected |
| Pseudomonas aeruginosa | It must not detect | It is not detected |
| Hemolytic streptococcus | It must not detect | It is not detected |
Conclusion: the examined project coliform of submitted sample, Pseudomonas aeruginosa, staphylococcus aureus, hemolytic streptococcus, bacterium bacterium
Fall sum, the testing result of fungus colony sum meets GB15979-2002's " Disposable Sanitary Accessory sanitary standard "
It is required that.
In order to further optimize the above technical scheme, any harmful chemical is not present through detection in this product.
In order to further optimize the above technical scheme, this product uses after brushing teeth sooner or later, and each 20ml gargles 20 seconds, gargles
It can spit behind oral cavity, gargle without clear water.
Each embodiment in this specification is described in a progressive manner, the highlights of each of the examples are with other
The difference of embodiment, the same or similar parts in each embodiment may refer to each other.For device disclosed in embodiment
For, since it is corresponded to the methods disclosed in the examples, so being described relatively simple, related place is said referring to method part
It is bright.
The foregoing description of the disclosed embodiments enables those skilled in the art to implement or use the present invention.
Various modifications to these embodiments will be readily apparent to those skilled in the art, as defined herein
General Principle can be realized in other embodiments without departing from the spirit or scope of the present invention.Therefore, of the invention
It is not intended to be limited to the embodiments shown herein, and is to fit to and the principles and novel features disclosed herein phase one
The widest scope of cause.
Claims (2)
1. a kind of antibacterial mouthwash, raw material include: deionized water, honeysuckle extract liquor, Cortex Magnoliae Officinalis extract liquor, catechin, left hand it is fragrant,
Citric acid, xylitol, peppermint, tea extraction liquid, licorice extract, benzoic acid.
2. a kind of antibacterial mouthwash according to claim 1, which is characterized in that the raw material proportioning are as follows: deionized water
88.732%, honeysuckle extract liquor 3%, Cortex Magnoliae Officinalis extract liquor 2.5%, catechin 2.5%, left hand perfume (or spice) 2%, citric acid 0.002%, xylitol
0.15%, peppermint 0.008%, tea extraction liquid 0.5%, licorice extract 0.6%, benzoic acid 0.08%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810940606.1A CN109363980A (en) | 2018-08-17 | 2018-08-17 | A kind of antibacterial mouthwash |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810940606.1A CN109363980A (en) | 2018-08-17 | 2018-08-17 | A kind of antibacterial mouthwash |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109363980A true CN109363980A (en) | 2019-02-22 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810940606.1A Pending CN109363980A (en) | 2018-08-17 | 2018-08-17 | A kind of antibacterial mouthwash |
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| CN (1) | CN109363980A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110236968A (en) * | 2019-07-03 | 2019-09-17 | 深圳市诗碧曼科技有限公司 | A kind of antibacterial mouthwash of anti-ageing healthcare and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1927160A (en) * | 2006-08-25 | 2007-03-14 | 青岛大学医学院附属医院 | Gargle and its preparing process |
| WO2007079331A2 (en) * | 2005-12-13 | 2007-07-12 | Richard Paul Bonfiglio | Antibacterial oral rinse formulation for preventing coronary artery disease |
| WO2011068812A1 (en) * | 2009-12-04 | 2011-06-09 | Colgate-Palmolive Company | Oral compositions containing a combination of natural extracts and related methods |
| CN105997659A (en) * | 2016-06-21 | 2016-10-12 | 江苏奇力康皮肤药业有限公司 | Anti-inflammation and anti-bacterium mouth wash |
| CN107184476A (en) * | 2017-06-16 | 2017-09-22 | 河北康正药业有限公司 | A kind of antibacterial mouthwash and preparation method thereof |
-
2018
- 2018-08-17 CN CN201810940606.1A patent/CN109363980A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007079331A2 (en) * | 2005-12-13 | 2007-07-12 | Richard Paul Bonfiglio | Antibacterial oral rinse formulation for preventing coronary artery disease |
| CN1927160A (en) * | 2006-08-25 | 2007-03-14 | 青岛大学医学院附属医院 | Gargle and its preparing process |
| WO2011068812A1 (en) * | 2009-12-04 | 2011-06-09 | Colgate-Palmolive Company | Oral compositions containing a combination of natural extracts and related methods |
| CN105997659A (en) * | 2016-06-21 | 2016-10-12 | 江苏奇力康皮肤药业有限公司 | Anti-inflammation and anti-bacterium mouth wash |
| CN107184476A (en) * | 2017-06-16 | 2017-09-22 | 河北康正药业有限公司 | A kind of antibacterial mouthwash and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 国家药典委员会: "《中华人民共和国药典临床用药须知：2015年版.中药饮片卷》", 30 September 2017, 中国医药科技出版社 * |
| 陈怡儒等: "《图解日用品安全全书》", 31 May 2015, 湖南科学技术出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110236968A (en) * | 2019-07-03 | 2019-09-17 | 深圳市诗碧曼科技有限公司 | A kind of antibacterial mouthwash of anti-ageing healthcare and preparation method thereof |
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Application publication date: 20190222 |