CN109350563A - A kind of composition of the oil containing borneol for nti-freckle - Google Patents
A kind of composition of the oil containing borneol for nti-freckle Download PDFInfo
- Publication number
- CN109350563A CN109350563A CN201811619694.1A CN201811619694A CN109350563A CN 109350563 A CN109350563 A CN 109350563A CN 201811619694 A CN201811619694 A CN 201811619694A CN 109350563 A CN109350563 A CN 109350563A
- Authority
- CN
- China
- Prior art keywords
- powder
- borneol
- freckle
- degrees celsius
- nti
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
This application provides one kind to be used for spot-eliminating composition, and comprising borneol oil, lemon and Rosa Damascana, wherein borneol oil is to extract to obtain from the borneol cinnamomum camphora limb and leaf that protease and zytase enzymolysis processing are crossed.
Description
Technical field
The present invention relates to skin care fields and enzymic preparation field, specifically, the present invention relates to be used for spot-eliminating composition, packet
Containing borneol oil, lemon and Rosa Damascana, wherein borneol oil is the kapur crossed from protease and zytase enzymolysis processing
It extracts and obtains in camphor tree limb and leaf.
Background technique
Color spot refers to spot different with ambient color, including freckle, blackspot, chloasma and senile plaque etc., belongs to pigment barrier
Impenetrability skin disease.Due to dermal melanin increase and the common face of one kind that is formed is brown or melanin pigmentation, damage appearance
The skin disease of property, is mainly in cheek and forehead position, aggravates after solarization.For a long time, color spot is always to perplex human skin
One of the problem of, in particular with the growth at age, the probability that color spot occurs in skin is also obviously increased, and influences body and skin
Beauty, many cosmetics are increasingly valued by people thus.Currently, the treatment method to color spot is more, have laser,
The physical therapies such as microwave, fulguration Chemical peeling art also have through chemical substances such as the chemical substances such as oral or injection vitamin C
Western medical treatment method, both methods improper use, possible pigment Eradicates in addition to, scar or other side effects etc., face
Chinese medicine conditioning works slowly, and the probability for desalinating spot is little.
Essential oil is derived from the extraction essence of the flower of plant, leaf, stem, root or fruit, without chemical pigment, without essence, is free of
Preservative is not in allergic phenomena and gradually has been favored by people.Borneol oil is from kapor (Cinnamomum
Camphora resulting volatile oil) is extracted, there is activating microcirculation and removing stasis medicinal, myogenic is antipruritic, Repercusion analgesia effect;And it is reported that also having
Old dead cell is removed, collagen is promoted to generate, desalinates melanin, softens the effect of causes scar tissue.But compared to effect by true
The drug (if any the compound medicine of oxidation bleaching effect) and method of disposal (such as the methods of freezing, laser nti-freckle) of verifying are cut,
The effect of borneol oil product is inaccurate/not significant.
In order to improve the effect of borneol cinnamomum camphora extraction, have using enzyme preparation (protease, cellulase, hemicellulose
Enzyme, pectase etc.) trial that borneol cinnamomum camphora is handled, and effectively raise the extraction effect of wherein borneol.But for
The improvement of extracted derived essential oil/effect, which there is no, clearly to be reported.
Summary of the invention
Applicant when improving borneol oil extract, discovery using zytase replace pectase commonly used in the prior art and
Cellulase processing borneol cinnamomum camphora significantly improves the content of linalool and carypohyllene in borneol oil.The borneol oil is used for skin care
When product, also achieving good freckle effect (has the effect of antibacterial anti-inflammatory, adjusts hyaluronic acid known to linalool and carypohyllene;
And may have structure based on xylan after xylanase treatment in the composition variation prompt borneol cinnamomum camphora branches and leaves of product, wherein
There may be the compounds for having freckle effect not detected, such as new sesquiterpenoids or steroid compound).
On the one hand, this application provides one kind to be used for spot-eliminating composition, which is characterized in that includes borneol oil.
Further, it also includes lemon and Rosa Damascana that this, which is used for spot-eliminating composition,.
Further, this is used in spot-eliminating composition, includes 5-20 parts of borneol oil by weight, lemon 1-10
Part, 5-15 parts of Rosa Damascana.
Further, this is used in spot-eliminating composition, by weight, 15 parts oily comprising borneol, and 5 parts of lemon, rose
10 parts of rare essential oil.
Further, the borneol oil is prepared by following method: enzymolysis processing borneol cinnamomum camphora limb and leaf;Ether
It impregnates;Distillation;It is dry.
Further, the borneol oil is prepared by following method: being weighed after borneol cinnamomum camphora limb and leaf are crushed
The water of 5 times of weight of powder is added in powder weight;Bromelain 200U/g powder is added, zytase 100U/g powder adjusts pH
It is digested 4 hours under to 6.0,45 degrees Celsius, is heated to 100 degrees Celsius of inactivators 5 minutes, filtered, retain solid portion;Powder is added
The ether of last 10 times of quality, impregnates 2h at room temperature;Distillation is until solvent no longer flows out under conditions of 45 degrees Celsius;It is placed in
It is 30 minutes dry in thermostatic drying chamber, organic solvent is removed, to obtain borneol oil.
Further, the lemon is prepared by following method: being taken lemon peel, is cut first with high-speed slice cutting machine
At the coarse fragments of 2-5mm;Under conditions of solid-liquid ratio 1:5-15, impregnated at room temperature with ether 2 hours;Under conditions of 50 DEG C
Distillation is until solvent no longer flows out;Drying 30 minutes in thermostatic drying chamber are placed in, remove organic solvent to get the lemon is arrived
Essential oil;The Rosa Damascana is prepared by following method: being taken dry rose, is cut into 2- with high-speed slice cutting machine first
Then the fragment of 5mm is ground into 10-50 mesh fine powder with pulverizer;Obtain rose powder;Stream of supercritical carbon dioxide is added in rose powder
In the extraction kettle of body extraction equipment, closes kettle cover and be passed through carbon dioxide pressurization extraction kettle internal pressure when temperature reaches 45 degrees Celsius
Power to 25Mpa, kept for 45 degrees Celsius, extract 5 hours, collect the product released in separating still, the decanter type through 5000r/min from
Scheming separating treatment divides and removes bottom moisture and impurity to get the Rosa Damascana is arrived.
On the other hand, the present invention provides the above-mentioned compositions for nti-freckle to prepare the application in spot-eliminating skin care product.
Further, the spot-eliminating skin care product is facial mask, face cream, lotion, Essence or facial cleanser.
On the other hand, the present invention provides a kind of preparation methods of borneol oil, comprising the following steps: by borneol cinnamomum camphora limb
Powder weight is weighed after crushing with leaf, and the water of 5 times of weight of powder is added;Bromelain 200U/g powder, zytase is added
100U/g powder adjusts pH to 6.0, digests 4 hours under 45 degrees Celsius, be heated to 100 degrees Celsius of inactivators 5 minutes, filter, retains
Solid portion;The ether of 10 times of quality of powder is added, impregnates 2h at room temperature;It is distilled to solvent not under conditions of 45 degrees Celsius
Until flowing out again;30 minutes dry, removal organic solvent is placed in thermostatic drying chamber, to obtain borneol oil.
It, can also be as required in the composition skin-care product in the present invention in addition to borneol oil, lemon and Rosa Damascana
Other essential oils, natural extract class product are added, or are known to be used in the medicinal compound of skin nursing, treatment.
In composition skin-care product in the present invention can also various excipient as required, including but not limited to wetting agent,
Lubricant, preservative, antioxidant, grinding agent etc..
Specific embodiment
Main agents and instrument:
Borneol cinnamomum camphora limb and leaf: same batch, purchase are regional from Shaoxing Shangyu;
Lemon peel and rose: same batch is purchased from suburb of Haikou City food processing and fresh flower plantation;
Bromelain: food-grade, the road Dong Henghua biotechnology Co., Ltd, 50000U/g;
Cellulase: food-grade, the road Dong Henghua biotechnology Co., Ltd, 10000U/g;
Zytase: food-grade, letter are got profit biotechnology Co., Ltd, 40000U/g;
GC-MS instrument: U.S. Varian, Varian4000 type:
Gas-chromatography: VF-5ms capillary column, 80-320 degrees Celsius of column temperature column temperature, lO degrees Celsius of temperature programming/min;Into
320 degrees Celsius of temperature of mouth, split ratio 12:1, carrier gas is helium;
Mass spectrum: electron energy 70eV;280 degrees Celsius of temperature of transmission, is composed using NIST05 by 220 degrees Celsius of ion source temperature
Library searching.
Other reagents and instrument are conventional domestic type and model.
Embodiment 1, the preparation of borneol oil, lemon, Rosa Damascana and nti-freckle compound essential oil.
Powder weight is weighed after borneol cinnamomum camphora limb and leaf are crushed, the water of 5 times of weight of powder is added;Bromelain is added
Enzyme 200U/g powder, zytase 100U/g powder adjust pH to 6.0, digest 4 hours under 45 degrees Celsius, be heated to 100 degrees Celsius
Inactivator 5 minutes, filtering retained solid portion;The ether of 10 times of quality of powder is added, impregnates 2h at room temperature;It is Celsius 45
Distillation is until solvent no longer flows out under conditions of degree;30 minutes dry, removal organic solvent is placed in thermostatic drying chamber, thus
Obtain borneol oil 1.
Powder weight is weighed after borneol cinnamomum camphora limb and leaf are crushed, the water of 5 times of weight of powder is added;Bromelain is added
Enzyme 200U/g powder, cellulase 100U/g powder adjust pH to 6.0, digest 4 hours under 45 degrees Celsius, be heated to 100 degrees Celsius
Inactivator 5 minutes, filtering retained solid portion;The ether of 10 times of quality of powder is added, impregnates 2h at room temperature;It is Celsius 45
Distillation is until solvent no longer flows out under conditions of degree;30 minutes dry, removal organic solvent is placed in thermostatic drying chamber, thus
Obtain borneol oil 2.
Powder weight is weighed after borneol cinnamomum camphora limb and leaf are crushed;The ether of 10 times of quality of powder is added, at room temperature
Impregnate 2h;Distillation is until solvent no longer flows out under conditions of 45 degrees Celsius;Drying 30 minutes in thermostatic drying chamber are placed in, are gone
Except organic solvent, to obtain borneol oil 3.
Lemon peel is taken, is cut into the coarse fragments of 2-5mm with high-speed slice cutting machine first;Under conditions of solid-liquid ratio 1:8, ether is used
It impregnates 2 hours at room temperature;Distillation is until solvent no longer flows out under conditions of 50 DEG C;Dry 30 are placed in thermostatic drying chamber
Minute, organic solvent is removed to get the lemon is arrived.
The Rosa Damascana is prepared by following method: being taken dry rose, is cut into first with high-speed slice cutting machine
Then the fragment of 2-5mm is ground into 10-50 mesh fine powder with pulverizer;Obtain rose powder;Supercritical carbon dioxide is added in rose powder
In the extraction kettle of fluid extraction device, closes kettle cover and be passed through in carbon dioxide pressurization extraction kettle when temperature reaches 45 degrees Celsius
Pressure extracts 5 hours to 25Mpa, 45 degrees Celsius of holding, collects the product released in separating still, the decanter type through 5000r/min
Centrifuge separating treatment divides and removes bottom moisture and impurity to get the Rosa Damascana is arrived.
Borneol oil 1/2/3, lemon, the Rosa Damascana of 10:2:5 volume is taken to be placed in container and be uniformly mixed respectively
Afterwards, filling that nti-freckle compound essential oil 1/2/3 is obtained in Ethereal oil bottle.
The GC-MS of 2 three kinds of borneol oil of embodiment is analyzed
Using the ingredient of GC-MS instrument above-mentioned and Parameter analysis borneol oil 1-3, it as a result see the table below 1 and (only list concern
Several ingredient results):
ND: it is not detected
The result shows that it includes borneol, linalool, carypohyllene that xylanase treatment borneol cinnamomum camphora limb and leaf, which have effectively facilitated,
The release of active compound inside, especially becomes apparent linalool and carypohyllene, it opposite contains when xylanase treatment
Amount increases 1-2 times and differs, and dramatically increasing the content of limonene in product (has the terpene of a few low content
Ingredient can't detect after enzymatic treatment).
The freckle effect of 3 nti-freckle compound essential oil of embodiment is surveyed
Choose the patient of the sunburn, butterfly macules and chloasma that suffer from general level, photographic measurement.Daily night sleeps preceding use
Using the nti-freckle compound essential oil 1 and 2 prepared in embodiment 1, evaluation effect after continuous 30 days.
Evaluation criterion:
Recovery from illness: color spot all subsides, and skin color is close to normally.Effective: color spot color is obviously thin out, and primary colors pinta stove goes out
Existing many places patch shape normal skin, the color spot recession gross area reach 50% or more of former lesion.Effective: color spot lighter subsides
Area reaches 30% or more of former lesion.Invalid: pretherapy and post-treatment color spot is substantially unchanged or aggravates.
2 nti-freckle compound essential oil of table, 1 effect
Color spot | Recovery from illness example | Effective example | Effective example | Invalid example | Total number of cases | Total effective rate |
Chloasma | 3 | 4 | 6 | 2 | 15 | 86.6% |
Sunburn | 2 | 5 | 4 | 1 | 12 | 91.7% |
Butterfly macules | 3 | 4 | 4 | 1 | 12 | 91.7% |
3 nti-freckle compound essential oil of table, 2 effect
Color spot | Recovery from illness example | Effective example | Effective example | Invalid example | Total number of cases | Total effective rate |
Chloasma | 1 | 2 | 7 | 2 | 12 | 83.3% |
Sunburn | 2 | 6 | 2 | 4 | 14 | 71.4% |
Butterfly macules | 2 | 2 | 5 | 3 | 12 | 75.0% |
It is above-mentioned statistics indicate that, no matter from efficient or from obvious effective rate, use bromelain and zytase enzyme
The essential oil effect of solution borneol cinnamomum camphora limb and leaf preparation is substantially better than the existing enzymolysis processing side using protease and cellulase
Essential oil prepared by formula, to efficient all significantly higher (the especially sunburn and butterfly macules) of various color spots.This may be derived from
Know the increase of the linalool and carypohyllene content that adjust hyaluronic acid effect with antibacterial anti-inflammatory, and is likely to occur/content increasing
The new terpene or steroid compound added.
The preparation of 4 freckle-removing mask of embodiment
Table 4, freckle-removing mask formula
Preparation process:
1. cleaning and sterilizing beaker used;
2. 2%941 solution manufacturing methods: 100ml deionized water being added in 250ml beaker, homogenizer is started and slowly will
2g941 is added to dissolution completely, if too thick addition 0.05g phosphoric acid to obtain the final product.
2.A phase weighs according to the ratio to be added in 250ml beaker, is heated to the dissolution of 90-95 degree completely, 50ml beaker is added in B
In stir evenly in advance after, add in A, keep the temperature 20 minutes;
3. C phase is added, and stir evenly, D is then added, stirs evenly;
4. the E stirred evenly in advance is added at 45 DEG C, stirs evenly, add F, stir evenly.
Claims (10)
1. one kind is used for spot-eliminating composition, which is characterized in that include borneol oil.
2. the composition according to claim 1 for nti-freckle, which is characterized in that also include lemon and rhodamine toner
Oil.
3. the composition according to claim 2 for nti-freckle, which is characterized in that include borneol oil 5- by weight
20 parts, 1-10 parts of lemon, 5-15 parts of Rosa Damascana.
4. the composition according to claim 3 for nti-freckle, which is characterized in that include borneol oil 15 by weight
Part, 5 parts of lemon, 10 parts of Rosa Damascana.
5. the composition according to any one of claims 1 to 4 for nti-freckle, it is characterised in that the borneol oil is to pass through
Following method preparation: enzymolysis processing borneol cinnamomum camphora limb and leaf;Ether impregnates;Distillation;It is dry.
6. the composition according to claim 5 for nti-freckle, it is characterised in that the borneol oil is prepared by following method
: powder weight is weighed after borneol cinnamomum camphora limb and leaf are crushed, the water of 5 times of weight of powder is added;Bromelain is added
200U/g powder, zytase 100U/g powder adjust pH to 6.0, digest 4 hours under 45 degrees Celsius, be heated to 100 degrees Celsius and go out
Enzyme 5 minutes living, filtering retained solid portion;The ether of 10 times of quality of powder is added, impregnates 2h at room temperature;At 45 degrees Celsius
Under conditions of distillation until solvent no longer flows out;30 minutes dry, removal organic solvent is placed in thermostatic drying chamber, thus
To borneol oil.
7. according to the described in any item compositions for nti-freckle of claim 2 to 6, it is characterised in that the lemon is logical
It crosses following method preparation: taking lemon peel, be cut into the coarse fragments of 2-5mm with high-speed slice cutting machine first;Solid-liquid ratio 1:5-15's
Under the conditions of, it is impregnated at room temperature with ether 2 hours;Distillation is until solvent no longer flows out under conditions of 50 DEG C;It is placed in constant temperature
It is 30 minutes dry in drying box, organic solvent is removed to get the lemon is arrived;The Rosa Damascana is by following method
Preparation: taking dry rose, be cut into the fragment of 2-5mm with high-speed slice cutting machine first, be then ground into 10-50 with pulverizer
Mesh fine powder;Obtain rose powder;Rose powder is added in the extraction kettle of supercritical carbon dioxide extraction device, closes kettle cover, when
When temperature reaches 45 degrees Celsius, being passed through pressure in carbon dioxide pressurization extraction kettle, to 25Mpa, 45 degrees Celsius of holding, extraction 5 is small
When, collect the product released in separating still, the sedimentation-type centrifuge separating treatment through 5000r/min point removes bottom moisture and miscellaneous
Matter to get arrive the Rosa Damascana.
8. the composition according to any one of claims 1 to 7 for nti-freckle is preparing the application in spot-eliminating skin care product.
9. application according to claim 8, which is characterized in that the spot-eliminating skin care product is facial mask, face cream, lotion, essence
Liquid or facial cleanser.
10. a kind of preparation method of borneol oil, comprising the following steps: weigh powder weight after crushing borneol cinnamomum camphora limb and leaf
The water of 5 times of weight of powder is added in amount;Bromelain 200U/g powder is added, zytase 100U/g powder adjusts pH to 6.0,
It is digested 4 hours under 45 degrees Celsius, is heated to 100 degrees Celsius of inactivators 5 minutes, filtered, retain solid portion;It is added 10 times of powder
The ether of quality, impregnates 2h at room temperature;Distillation is until solvent no longer flows out under conditions of 45 degrees Celsius;It is dry to be placed in constant temperature
It is 30 minutes dry in dry case, organic solvent is removed, to obtain borneol oil.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201811619694.1A CN109350563B (en) | 2018-12-28 | 2018-12-28 | Composition containing borneol oil for removing freckles |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201811619694.1A CN109350563B (en) | 2018-12-28 | 2018-12-28 | Composition containing borneol oil for removing freckles |
Publications (2)
Publication Number | Publication Date |
---|---|
CN109350563A true CN109350563A (en) | 2019-02-19 |
CN109350563B CN109350563B (en) | 2021-04-30 |
Family
ID=65329426
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201811619694.1A Active CN109350563B (en) | 2018-12-28 | 2018-12-28 | Composition containing borneol oil for removing freckles |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN109350563B (en) |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104095797A (en) * | 2014-08-05 | 2014-10-15 | 中国热带农业科学院热带作物品种资源研究所 | Blumea balsamifera composite with freckle removing effect and application thereof |
CN105342885A (en) * | 2015-11-25 | 2016-02-24 | 杭州水木龙脑生物科技有限公司 | Essential oil-protein composite formula for repairing skin injuries |
CN107473942A (en) * | 2017-09-19 | 2017-12-15 | 北京国康本草物种生物科学技术研究院有限公司 | The extracting method of natural borneol |
KR101822752B1 (en) * | 2016-08-03 | 2018-01-29 | 전남대학교산학협력단 | Manufacturing method for enzymatic extracts of deer antlerdeer antler containing highly physiologically active ingredients of deer antler and enzymatic extracts of deer antlerdeer antler using the same |
CN108484362A (en) * | 2018-05-16 | 2018-09-04 | 江南大学 | A method of improving natural borneol recovery rate |
CN108542806A (en) * | 2018-07-04 | 2018-09-18 | 范加家 | A kind of light spot compound borneol essential oil of anti-acne and preparation method thereof |
CN108670937A (en) * | 2018-07-17 | 2018-10-19 | 山西保仁堂生物科技有限责任公司 | A kind of vegetalitas facial masks for whitening faces and removing spots and preparation method thereof |
-
2018
- 2018-12-28 CN CN201811619694.1A patent/CN109350563B/en active Active
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104095797A (en) * | 2014-08-05 | 2014-10-15 | 中国热带农业科学院热带作物品种资源研究所 | Blumea balsamifera composite with freckle removing effect and application thereof |
CN105342885A (en) * | 2015-11-25 | 2016-02-24 | 杭州水木龙脑生物科技有限公司 | Essential oil-protein composite formula for repairing skin injuries |
KR101822752B1 (en) * | 2016-08-03 | 2018-01-29 | 전남대학교산학협력단 | Manufacturing method for enzymatic extracts of deer antlerdeer antler containing highly physiologically active ingredients of deer antler and enzymatic extracts of deer antlerdeer antler using the same |
CN107473942A (en) * | 2017-09-19 | 2017-12-15 | 北京国康本草物种生物科学技术研究院有限公司 | The extracting method of natural borneol |
CN108484362A (en) * | 2018-05-16 | 2018-09-04 | 江南大学 | A method of improving natural borneol recovery rate |
CN108542806A (en) * | 2018-07-04 | 2018-09-18 | 范加家 | A kind of light spot compound borneol essential oil of anti-acne and preparation method thereof |
CN108670937A (en) * | 2018-07-17 | 2018-10-19 | 山西保仁堂生物科技有限责任公司 | A kind of vegetalitas facial masks for whitening faces and removing spots and preparation method thereof |
Non-Patent Citations (1)
Title |
---|
李兆双等: "樟树精油提取方法研究与进展", 《广州化工》 * |
Also Published As
Publication number | Publication date |
---|---|
CN109350563B (en) | 2021-04-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN108158869B (en) | Antibacterial wet tissue liquid, wet tissue and preparation method of wet tissue | |
CN115531473B (en) | Compound essential oil for treating skin diseases and pharmaceutical composition containing same | |
US20190216123A1 (en) | Preparation of mixed tea composition comprising aloeswood | |
JP2017039697A (en) | Composition | |
JP2008184440A (en) | External preparation for skin for ameliorating cytotoxicity of ultraviolet light | |
CN107034014B (en) | A kind of francolin tea compound essential oil and its preparation method and application | |
CN116712358A (en) | Compound essential oil for skin and pharmaceutical composition containing same | |
KR100472861B1 (en) | Distillation method of Japanese Cypress(Chamaecyparis obtusa essential oil alleviating against blood pressure by promoted heating system | |
CN109350563A (en) | A kind of composition of the oil containing borneol for nti-freckle | |
KR102335222B1 (en) | Composition for decreasing smell, treating demodex infestations and promoting growth of hair, and manufacturing mehtod thereof | |
CA2437321C (en) | Vapor fraction from seeds of glycine max (l.) merr. and composition thereof | |
JP4754834B2 (en) | Cosmetics | |
Zhou et al. | Active constituents of Litsea cubeba | |
CN113750163A (en) | Artemisia annua essential oil and white tea essential oil for treating acne and composition thereof | |
CN113881503A (en) | Artemisia annua essential oil and white tea essential oil with anti-inflammatory effect, and their composition | |
US7282226B2 (en) | Vapor fraction from seeds of Glycine max (L.) Merr. and composition thereof | |
CN108992392A (en) | A kind of skin care compositions and application containing Porcine HGF and peony extract | |
KR100433055B1 (en) | Cosmetic composition for cutis elastica or skin-moisture containing Trichosanthes kirilowii | |
CN108815235A (en) | A kind of antipruritic antiphlogistine in exterior-applied plant source and preparation method thereof | |
EP1506782B1 (en) | Vapor fraction from seeds of glycine max (L.) merr. and composition thereof | |
KR102154058B1 (en) | Method for preparing hair growth treatment containing blueberry and garlic peel extract as an active ingredient | |
KR102540470B1 (en) | Composition for external application for skin containing fresh ginseng steamed water obtained by vacuum drying at room temperature | |
KR102610940B1 (en) | Preparing method of cosmetic composition using skin cosmetic solution | |
Nurmala et al. | The Effectiveness of the Antiinfamation Combination Gel of Okra Fruit (Abelmoschus esculentus) Extracts and Shallots Extract (Allium cepa L.) | |
Quan et al. | ACTIVE CONSTITUENTS OF LITSEA CUBEBA. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20220402 Address after: 510006 room 316, building 1, Department of Guangdong Pharmaceutical University, No. 280, Waihuan East Road, Xiaoguwei street, Panyu District, Guangzhou City, Guangdong Province Patentee after: Junan doctor group (Guangdong) Co.,Ltd. Address before: Room 17D, 26 Renmin Avenue, Meilan District, Haikou City, Hainan Province Patentee before: HAINAN HAIYAOBENCAO BIOTECHNOLOGY Co.,Ltd. |