CN109266511A - A kind of gene detection system based on robot - Google Patents
A kind of gene detection system based on robot Download PDFInfo
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- CN109266511A CN109266511A CN201810922574.2A CN201810922574A CN109266511A CN 109266511 A CN109266511 A CN 109266511A CN 201810922574 A CN201810922574 A CN 201810922574A CN 109266511 A CN109266511 A CN 109266511A
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- gene
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- nucleic acid
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
Abstract
The invention discloses a kind of gene detection systems based on robot, including gene assaying device, data transmission blocks, data reception module, computer, display screen, memory module and enquiry module, the information output of the gene assaying device and the information input terminal of data transmission blocks connect, the information output of the data transmission blocks and the information input terminal of data reception module connect, the information output of the data reception module and the information input terminal of computer connect, the first information output end of the computer and the information input terminal of memory module connect, the information output of the memory module and the information input terminal of enquiry module connect, the information output of the enquiry module and the first information input terminal of display screen connect.The gene detection system based on robot is had many advantages, such as that simple to operate, required human resources are few, can be used with popularity.
Description
Technical field
The present invention relates to gene detection system application field, in particular to a kind of gene detection system based on robot.
Background technique
Gene is the basic unit of heredity, carries the DNA or RNA sequence of hereditary information, by duplication, hereditary information
The next generation is passed to, instructs the synthesis of protein to express the hereditary information entrained by oneself, to control the property of bion
Shape expression.Genetic test is the technology detected by blood, other body fluid or cell to DNA, is to take detected person periphery
Venous blood or other histocytes after expanding its gene information, are believed the DNA molecular in detected person's cell by particular device
Whether normally breath detects, analyze gene type contained by it and gene defect and its expressive function a kind of method, thus
The gene information for allowing one to understand oneself specifies the cause of disease or predicts the risk that body suffers from certain disease.
Genetic test can diagnose the illness, and can be used for the prediction of disease risks.Medical diagnosis on disease is with genetic test skill
Art detects the mutated gene for causing genetic disease.Current most widely used genetic test is the inspection of newborn's genetic disease
It surveys, the auxiliary diagnosis of the diagnosis of genetic disease and certain common diseases.
The ancillary equipment that existing gene detection system needs is more, and troublesome in poeration, required human resources are more, cause
The wastes of human resources.
Summary of the invention
The purpose of the present invention is to provide the gene detection systems based on robot, to solve to propose in above-mentioned background technique
The problem of.
Realizing the technical solution of above-mentioned purpose is: a kind of gene detection system based on robot, including genetic test dress
It sets, data transmission blocks, data reception module, computer, display screen, memory module and enquiry module, the genetic test fill
The information output set and the information input terminal of data transmission blocks connect, the information output and number of the data transmission blocks
It is connected according to the information input terminal of receiving module, the information output of the data reception module and the information input terminal of computer connect
It connects, the first information output end of the computer and the information input terminal of memory module connect, and the information of the memory module is defeated
The connection of the information input terminal of outlet and enquiry module, the information output of the enquiry module and the first information of display screen input
End connection, the second information output of the computer and the second information input terminal of display screen connect.
Preferably, the gene assaying device includes the instrument for extracting nucleic acid set gradually according to genetic test process, PCR expansion
Increase instrument, electrophoresis apparatus and photo module, the information output of the photo module and the information input terminal of data transmission blocks connect.
Preferably, instrument for extracting nucleic acid extracts required nucleic acid from sample；Nucleic acid and additional primer and four kinds of deoxidations
Nucleotide is put into PCR (polymerase chain reaction) amplification instrument, expands purpose nucleic acid；
Nucleic acid after amplification is added in the glue sample in electrophoresis apparatus, electrophoresis is carried out；
Light source in electrophoresis apparatus generates excitation line and excites the thermochromic agent being incorporated on nucleic acid molecules, generates detection light,
Detection light is captured by photo module, shows position of each nucleic acid fragment in gel.
Preferably, the data transmission blocks are used to the gene information that photo module captures being transferred to data reception
Block, the data reception module gene information that sending module is sent for receiving data, and gene information is transmitted to calculating
Machine.
Preferably, the computer is used for:
The gene information that data reception module is sent is received, and gene information is analyzed；
Analysis result is sent to display screen；
Analysis result is sent to memory module.
Preferably, for the memory module for storing the analysis result of gene information, the display screen is used for will
The analysis result for the gene information that computer and enquiry module are sent is shown.
Preferably, the enquiry module is used to retrieve the analysis of the gene information stored in memory module as a result, and by base
Because the analysis result of information is sent to display screen.
Preferably, the gene assaying device and data transmission blocks are arranged on robot body.
The beneficial effects of the present invention are: being somebody's turn to do the gene detection system based on robot, sample is taken, instrument for extracting nucleic acid is passed through
Nucleic acid and additional primer that instrument for extracting nucleic acid extracts and four kinds of deoxynucleotides are put into PCR by the nucleic acid needed for extracting
Amplification instrument rapidly amplifies purpose nucleic acid, and the nucleic acid after amplification is added in the glue sample in electrophoresis apparatus, electrophoresis is carried out,
In electrophoresis process, the nucleic acid molecules of different fragments size are separated, meanwhile, the light source in electrophoresis apparatus generates excitation line and swashs
The thermochromic agent being incorporated on nucleic acid molecules is sent out, detection light is generated, detection light is captured by photo module, thus aobvious
Position of the different size of nucleic acid fragment in gel is shown, photo module passes through data transmission blocks, data reception module will
The gene information of capture is transferred to the computer for being equipped with genetic analysis software, and computer analyzes genetic results, operation
It is simple and convenient, required ancillary equipment and instrument are simplified, manipulates the required of relevant device to reduce in genetic test work
Personnel have saved human resources；Computer is sent to memory module for result is analyzed, and is retrieved in memory module by enquiry module
The analysis of the gene information of storage is as a result, enable staff to check analysis as a result, easy to use at any time.
Detailed description of the invention
Fig. 1 is system schematic of the invention；
Fig. 2 is gene assaying device structural block diagram of the invention.
In figure: 1 gene assaying device, 2 data transmission blocks, 3 data reception modules, 4 computers, 5 display screens, 6 storages
Module, 7 enquiry modules, 8 instrument for extracting nucleic acid, 9PCR amplification instrument, 10 electrophoresis apparatuses, 11 photo modules.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
The present invention provides the gene detection system as shown in Figs. 1-2 based on robot, including gene assaying device 1,
Data transmission blocks 2, data reception module 3, computer 4, display screen 5, memory module 6 and enquiry module 7, the genetic test
The information output of device 1 is connect with the information input terminal of data transmission blocks 2, the information output of the data transmission blocks 2
End is connect with the information input terminal of data reception module 3, the information output of the data reception module 3 and the letter of computer 4
Input terminal connection is ceased, the first information output end of the computer 4 is connect with the information input terminal of memory module 6, the storage
The information output of module 6 is connect with the information input terminal of enquiry module 7, the information output of the enquiry module 7 and display
The first information input terminal connection of screen 5, the second information output of the computer 4 and the second information input terminal of display screen 5
Connection.Gene assaying device 1 and data transmission blocks 2 are arranged on robot body, and robot has respective function, respective
Genetic test is realized on the basis of function.
Specifically, the gene assaying device 1 includes instrument for extracting nucleic acid 8, the PCR set gradually according to genetic test process
Amplification instrument 9, electrophoresis apparatus 10 and photo module 11, the information output of the photo module 11 and the information of data transmission blocks 2
Input terminal connection.
Specifically, the genetic test process includes:
S1, sample is taken, required nucleic acid is extracted by instrument for extracting nucleic acid 8；
S2, nucleic acid and additional primer that instrument for extracting nucleic acid 8 extracts and four kinds of deoxynucleotides are put into PCR amplification
Instrument 9, rapidly amplifies purpose nucleic acid；
S3, the nucleic acid after amplification is added in the glue sample in electrophoresis apparatus 10, carries out electrophoresis；
S4, in electrophoresis process, the nucleic acid molecules of different fragments size are separated, meanwhile, the light in electrophoresis apparatus 10
Source generates excitation line and excites the thermochromic agent being incorporated on nucleic acid molecules, generates detection light, is detected by 11 Duis of photo module
Light is captured, to show position of the different size of nucleic acid fragment in gel；
The gene information of capture is transferred to peace by data transmission blocks 2, data reception module 3 by S5, photo module 11
Computer 4 equipped with genetic analysis software, computer 4 analyze genetic results.
Specifically, the data transmission blocks 2 are used to the gene information that photo module 11 captures being transferred to data receiver
Module 3, the data reception module 3 gene information that sending module 2 is sent for receiving data, and gene information is transmitted to
Computer 4.
Specifically, the computer 4 is used for:
The gene information that data reception module 3 is sent is received, and gene information is analyzed；
Analysis result is sent to display screen 5；
Analysis result is sent to memory module 6.
Specifically, the memory module 6 is for storing the analysis result of gene information, the display screen 5 is used for
The analysis result for the gene information that computer 4 and enquiry module 7 are sent is shown.
Specifically, the enquiry module 7 is used to retrieve the analysis of the gene information stored in memory module 6 as a result, and will
The analysis result of gene information is sent to display screen 5.
To sum up, it is somebody's turn to do the gene detection system based on robot when in use, takes the sample detected, utilize film
Absorption method extracts required nucleic acid by instrument for extracting nucleic acid 8, the nucleic acid and additional primer that instrument for extracting nucleic acid 8 is extracted
It is put into PCR amplification instrument 9 with four kinds of deoxynucleotides, rapidly amplifies purpose nucleic acid, electrophoresis is added in the nucleic acid after amplification
In glue sample in instrument 10, electrophoresis is carried out, in electrophoresis process, the nucleic acid molecules of different fragments size are separated, meanwhile, electricity
Light source in swimming instrument 10 generates excitation line and excites the thermochromic agent being incorporated on nucleic acid molecules, generates detection light, detects light
It is photographed module 11 through filter to capture, to show position of the different size of nucleic acid fragment in gel, mould of taking pictures
The gene information of capture is transferred to by data transmission blocks 2, data reception module 3 and is equipped with genetic analysis software by block 11
Computer 4, computer 4 analyze genetic results, and wherein genetic analysis software is the prior art, are not repeating herein；Meter
Calculation machine 4 is sent to memory module 6 for result is analyzed, and can retrieve the gene stored in memory module 6 at any time by enquiry module 7
The analysis of information is as a result, improve practicability.The gene detection system based on robot has simple to operate, required
The advantages that human resources are few, can be used with popularity.
Above embodiments are used for illustrative purposes only, rather than limitation of the present invention, the technology people in relation to technical field
Member, without departing from the spirit and scope of the present invention, can also make various transformation or modification, therefore all equivalent
Technical solution also should belong to scope of the invention, should be limited by each claim.
Claims (8)
1. a kind of gene detection system based on robot, which is characterized in that send mould including gene assaying device (1), data
Block (2), data reception module (3), computer (4), display screen (5), memory module (6) and enquiry module (7), the gene inspection
The information output for surveying device (1) is connect with the information input terminal of data transmission blocks (2), the data transmission blocks (2)
Information output is connect with the information input terminal of data reception module (3), the information output of the data reception module (3) with
The information input terminal of computer (4) connects, and the first information output end of the computer (4) and the information of memory module (6) are defeated
Enter end connection, the information output of the memory module (6) is connect with the information input terminal of enquiry module (7), the inquiry mould
The information output of block (7) is connect with the first information input terminal of display screen (5), the second information output of the computer (4)
End is connect with the second information input terminal of display screen (5).
2. a kind of gene detection system based on robot according to claim 1, which is characterized in that the genetic test
Device (1) include the instrument for extracting nucleic acid (8) set gradually according to genetic test process, PCR amplification instrument (9), electrophoresis apparatus (10) and
The information output of photo module (11), the photo module (11) is connect with the information input terminal of data transmission blocks (2).
3. a kind of gene detection system based on robot according to claim 2, which is characterized in that instrument for extracting nucleic acid
(8) required nucleic acid is extracted from sample；
Nucleic acid and additional primer and four kinds of deoxynucleotides are put into PCR amplification instrument (9), expand purpose nucleic acid；
Nucleic acid after amplification is added in the glue sample in electrophoresis apparatus (10), electrophoresis is carried out；
Light source in electrophoresis apparatus (10) generates excitation line and excites the thermochromic agent being incorporated on nucleic acid molecules, generates detection light,
Detection light is captured by photo module (11), shows position of each nucleic acid fragment in gel.
4. a kind of gene detection system based on robot according to claim 3, which is characterized in that the data are sent
Module (2) is used to the gene information that photo module (11) capture being transferred to data reception module (3), the data reception module
(3) gene information that sending module (2) is sent for receiving data, and gene information is transmitted to computer (4).
5. a kind of gene detection system based on robot according to claim 4, which is characterized in that the computer
(4) it is used for:
The gene information that data reception module (3) are sent is received, and gene information is analyzed；
Analysis result is sent to display screen (5)；
Analysis result is sent to memory module (6).
6. a kind of gene detection system based on robot according to claim 1, which is characterized in that the memory module
(6) for storing the analysis result of gene information, the display screen (5) is used for computer (4) and enquiry module (7)
The analysis result of the gene information of transmission is shown.
7. a kind of gene detection system based on robot according to claim 1, which is characterized in that the enquiry module
(7) for retrieving the analysis of the gene information stored in memory module (6) as a result, and being sent to the analysis result of gene information
Display screen (5).
8. a kind of gene detection system based on robot according to claim 1, which is characterized in that the genetic test
Device (1) and data transmission blocks (2) are arranged on robot body.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810922574.2A CN109266511A (en) | 2018-08-14 | 2018-08-14 | A kind of gene detection system based on robot |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810922574.2A CN109266511A (en) | 2018-08-14 | 2018-08-14 | A kind of gene detection system based on robot |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113667580A (en) * | 2021-08-01 | 2021-11-19 | 杭州憶盛医疗科技有限公司 | Gene detection device and detection method |
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| CN1394234A (en) * | 2000-09-06 | 2003-01-29 | 蒂莫西·A·霍奇 | System, method and apparatus for transgenic and targeted mutagenesis screening |
| US20030175782A1 (en) * | 2002-03-12 | 2003-09-18 | Yokogawa Electric Corporation | Genetic diagnosis/analysis apparatus and genetic diagnosis support system using the apparatus |
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| CN206375885U (en) * | 2016-12-21 | 2017-08-04 | 北京擎科新业生物技术有限公司 | A kind of gene detection system |
| CN107338180A (en) * | 2011-10-21 | 2017-11-10 | 尹特根埃克斯有限公司 | sample preparation, processing and analysis system |
| CN107644151A (en) * | 2017-09-01 | 2018-01-30 | 东莞博奥木华基因科技有限公司 | A kind of data management-control method and system for genetic test laboratory |
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Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1394234A (en) * | 2000-09-06 | 2003-01-29 | 蒂莫西·A·霍奇 | System, method and apparatus for transgenic and targeted mutagenesis screening |
| US20030175782A1 (en) * | 2002-03-12 | 2003-09-18 | Yokogawa Electric Corporation | Genetic diagnosis/analysis apparatus and genetic diagnosis support system using the apparatus |
| CN107338180A (en) * | 2011-10-21 | 2017-11-10 | 尹特根埃克斯有限公司 | sample preparation, processing and analysis system |
| CN105378110A (en) * | 2013-04-17 | 2016-03-02 | 生命技术公司 | Gene fusions and gene variants associated with cancer |
| CN206375885U (en) * | 2016-12-21 | 2017-08-04 | 北京擎科新业生物技术有限公司 | A kind of gene detection system |
| CN107644151A (en) * | 2017-09-01 | 2018-01-30 | 东莞博奥木华基因科技有限公司 | A kind of data management-control method and system for genetic test laboratory |
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| CN113667580A (en) * | 2021-08-01 | 2021-11-19 | 杭州憶盛医疗科技有限公司 | Gene detection device and detection method |
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