CN109221598A - Subtract anti-feed addictive and its processing method containing Radix Astragali or Radix Astragali stem, leaf, flower - Google Patents

Subtract anti-feed addictive and its processing method containing Radix Astragali or Radix Astragali stem, leaf, flower Download PDF

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CN109221598A
CN109221598A CN201811418281.7A CN201811418281A CN109221598A CN 109221598 A CN109221598 A CN 109221598A CN 201811418281 A CN201811418281 A CN 201811418281A CN 109221598 A CN109221598 A CN 109221598A
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parts
radix astragali
powders
flower
leaf
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CN109221598B (en
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王晓明
王鹤融
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Greater Khingan Range North Tianyuan Biological Science And Technology Co Ltd
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Greater Khingan Range North Tianyuan Biological Science And Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23JPROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A23J1/10Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from hair, feathers, horn, skins, leather, bones, or the like
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23JPROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00Working-up of proteins for foodstuffs
    • A23J3/14Vegetable proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23JPROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00Working-up of proteins for foodstuffs
    • A23J3/30Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A23J3/341Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23JPROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00Working-up of proteins for foodstuffs
    • A23J3/30Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A23J3/346Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of vegetable proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/12Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/20Animal feeding-stuffs from material of animal origin
    • A23K10/26Animal feeding-stuffs from material of animal origin from waste material, e.g. feathers, bones or skin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A23K10/37Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/142Amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/142Amino acids; Derivatives thereof
    • A23K20/147Polymeric derivatives, e.g. peptides or proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/158Fatty acids; Fats; Products containing oils or fats
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/22Compounds of alkali metals
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/26Compounds containing phosphorus
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/30Oligoelements
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    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
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Abstract

Subtract anti-feed addictive and its processing method containing Radix Astragali or Radix Astragali stem, leaf, flower the invention discloses a kind of.It is described to subtract the raw material that anti-feed addictive includes following weight parts: 5-10 parts of astragalus membranaceus powders, 3-5 parts of black bean powders, 1-3 parts of jujube powders, 2-4 parts of pumpkin seed powders, 5-8 parts of Kelp Powders, 0.5-1.5 parts of egg-shell meals, 0.02-0.04 parts of methionine, 0.01-0.03 parts of zinc sulfate, 30-50 parts of alfalfa meals containing Radix Astragali or Radix Astragali stem, leaf, flower;The astragalus membranaceus powder is by one of the root of Radix Astragali, stem, leaf or flower or a variety of powder obtained after drying, crushing.The beneficial effect for subtracting anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower of the invention is: the astragalus root components contained have effects that improve immunity of livestock, improve disease resistance, subtract anti-feed addictive without containing antibiotic and hormone medicine containing Radix Astragali or Radix Astragali stem, leaf, flower, it is non-hazardous to livestock and poultry and environment, it is added in the common diet feed of livestock and poultry the nutrient content that can improve feed, feed palatability is good, digestibility is high, feeding livestock and poultry can improve the speed of growth and fertility, reduce diarrhea rate and the death rate.

Description

Subtract anti-feed addictive and its processing method containing Radix Astragali or Radix Astragali stem, leaf, flower
Technical field
The present invention relates to a kind of feed addictive, subtract anti-feed containing Radix Astragali or Radix Astragali stem, leaf, flower more particularly to a kind of Additive and its processing method.
Background technique
Radix Astragali is a kind of Chinese herbal medicine, and medicinal study has more than 2000 years history so far, and Radix Astragali has enhancing immunity of organism Function, liver protection, diuresis, anti-aging, resisting stress, decompression and extensive antibacterial action.Experimental nephritis proteinuria can be eliminated, is enhanced Myocardial contractive power adjusts blood-sugar content.Energy coronary artery dilator, improves myocardial blood supply, improves immune function, delaying cell aging Process.Therefore Radix Astragali is added in food frequently as natural health-care products.
Antibiotic uses existing more than 50 years history as feed addictive in the world, but makes with antibiotic With discovery antibiotic dosage is bigger, and the drug resistance of animal is stronger, and immunity is lower, and more liable to illness, the cost of medication is higher. Meanwhile abuse of antibiotics also will cause the problems such as animal derived food antibiotic residue and destruction ecological environment, these problems The development of animal husbandry is not only influenced, while directly affecting human health.Therefore exploitation adds without the animal and fowl fodder of antibiotic, hormone Agent is added to become urgent problem to be solved.Subtracting anti-feed is with microorganism, complex enzyme for biological feed fermentation agent strain, by feed original Material is converted into microbial bacteria body protein, bioactive micro peptide amino acid, microbial activity probiotics, complex enzyme formulation and is integrated Fermented feed.The amino acid for being easy to lack in conventional feed can be made up by subtracting anti-feed not only, and can make other roughages Raw material nutrition converts rapidly, reaches enhancing and digests and absorbs effect.
Subtract anti-feed addictive and refers to the feed without drugs such as antibiotic, hormone, antipsychotics, pigment, clenbuterol hydrochlorides Additive.It is added to have in the conventional feed of livestock and poultry and improves feed protein, amino acid, microelement, prebiotic bacterial content, mentions The speed of growth of high livestock and poultry improves body immunity, enhances the effect of fertility.It is of the invention containing Radix Astragali or Radix Astragali stem, leaf, Colored to subtract anti-feed addictive nutrition comprehensive, is free of antibiotic and hormone medicine, non-hazardous to livestock and poultry, astragalus root components, which have, to be mentioned The effect of high immunity of livestock, reduction illness, being added in common daily ration can promote growth of animals or poultry to breed, and reduce diarrhea, death Rate.
Summary of the invention
Subtract anti-feed addictive and its processing containing Radix Astragali or Radix Astragali stem, leaf, flower the purpose of the present invention is to provide a kind of Method.
Specific technical solution is as follows:
It is a kind of to subtract anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower, the raw material including following weight parts: 5-10 parts Astragalus membranaceus powder, 3-5 part black bean powder, 1-3 parts of jujube powders, 2-4 parts of pumpkin seed powders, 5-8 parts of Kelp Powders, 0.5-1.5 parts of egg-shell meals, 0.02-0.04 parts of methionine, 0.01-0.03 parts of zinc sulfate, 30-50 parts of alfalfa meals;The astragalus membranaceus powder be by the root of Radix Astragali, stem, One of leaf or flower or a variety of powder obtained after drying, crushing.
It is a kind of to subtract anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower including following heavy in one embodiment of the invention Measure the raw material of part: 5-10 parts of astragalus membranaceus powders, 3-5 parts of semen sojae atricolor ferment powders, 1-3 parts of jujube powders, 2-4 parts of pumpkin seed powders, 5-8 portions of kelps Powder, 0.5-1.5 part egg-shell meal, 0.02-0.04 parts of methionine, 0.01-0.03 parts of zinc sulfate, 30-50 parts of alfalfa meals;The Radix Astragali Powder is by one of the root of Radix Astragali, stem, leaf or flower or a variety of powder obtained after drying, crushing.
It is a kind of to subtract anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower including following in another embodiment of the present invention The raw material of parts by weight: 5-10 parts of astragalus membranaceus powders, 3-5 parts of semen sojae atricolor ferment powders, 1-3 parts of jujube powders, 2-4 parts of pumpkin seed powders, 1-3 parts of red scapes Its extract, 5-8 part Kelp Powder, 0.5-1.5 parts of egg-shell meals, 0.02-0.04 methionine, 0.01-0.03 parts of zinc sulfate, 30-50 Part alfalfa meal;The astragalus membranaceus powder is by one of the root of Radix Astragali, stem, leaf or flower or a variety of powder obtained after drying, crushing End.
In another embodiment of the present invention, a kind of to subtract anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower, feature exists In the raw material including following weight parts: 5-10 parts of astragalus membranaceus powders, 3-5 parts of semen sojae atricolor ferment powders, 1-3 parts of jujube powders, 2-4 parts of pumpkins Powder, 1-3 part gadol extract, 5-8 parts of Kelp Powders, 0.5-1.5 parts of egg-shell meals, 0.02-0.04 methionine, 0.01-0.03 parts Zinc sulfate, 30-50 part alfalfa meal, 0.5-1.5 parts of flavor peptides;The astragalus membranaceus powder is by one of the root of Radix Astragali, stem, leaf or flower Or a variety of powder obtained after drying, crushing.
Preferably, astragalus root, semen sojae atricolor, the jujube of stoning, pumpkin, kelp, eggshell is 6-12 hours dry at 40-60 DEG C Afterwards, 100 meshes are smashed it through respectively, obtain astragalus membranaceus powder, black bean powder, jujube powder, pumpkin seed powder, Kelp Powder, egg-shell meal.
The semen sojae atricolor ferment powder the preparation method comprises the following steps: semen sojae atricolor after dry 6-12 hours, is smashed it through 100 at 40-60 DEG C Mesh obtains black bean powder, and it is 60-80 centimetres that black bean powder, which is paved into diameter, with a thickness of the cake of 3-5cm, is steamed with 100-120 DEG C of water Gas steams 40-80 minutes, takes 50-100g black bean powder to be added in 100-150g water after natural cooling, adds 0.2-1g β-Portugal After mixing, enzymatic hydrolysis obtains for 120-180 minutes under conditions of temperature is 45-60 DEG C for dextranase, 0.5-1.5g zytase Mixture A, into mixture A be added 2-5 part sugar sources, temperature for 50-70 DEG C sealing and fermenting 72-108 hours, then in temperature Mixture B is obtained within sealing and fermenting 12-24 hours for 30-40 DEG C, and mixture B is placed to 10-20 points in 90-110 DEG C of baking oven Clock is sterilized, then 35-50 DEG C vacuum drying 24-48 hours, obtain semen sojae atricolor ferment powder;The sugar source is soy oligosaccharides One of sugar, inulin, arabogalactan;It is further preferred that the sugar source is arabogalactan.
The gadol extract the preparation method is as follows: root of kirilow rhodiola is smashed it through 100 meshes, take root of kirilow rhodiola powder 30-50g is added in the ethanol water that 350-700g mass fraction is 30-50%, is stirred under conditions of temperature is 60-80 DEG C It mixes 24-36 hours, crosses 200 meshes, obtain first-time filtrate and filter residue, it is 45- that filter residue, which is added to 100-300g mass fraction, It in 65% ethanol water, is stirred 5-8 hours under conditions of temperature is 70-85 DEG C, crosses 200 meshes, obtain secondary filtrate, Merge filtrate twice, thick paste is dried under reduced pressure by the thick paste that relative density is 1.3-1.6 when heating evaporation is concentrated into 50 DEG C of measurement To gadol extract.
Preferably, the flavor peptide extracts from one of chicken bone, Pleurotus eryngii, fish-bone or a variety of.
The processing method of the flavor peptide for extracting from chicken bone are as follows: reject the meat of chicken bone surface and with water by surface washing After clean, it through drying, crushed 200 meshes, obtain chick bone powder, 200-300g chick bone powder 250-500g boiling is taken to boil and continue 200 meshes are crossed in boiling 10-20 minutes while hot, retain filter residue, and rinse filter residue surface, drip with 150-300g, 50-70 DEG C of water Filter residue is added to 200-400g, temperature as in 50-75 DEG C of water, stirring is added after 30-60 minutes by the moisture on dry filter residue surface 1-3g flavor protease, 1-5g alkali protease continue in temperature to be that 50-75 DEG C of stopping after stirring 10-20 minute is stirred, 50-75 DEG C obtains enzymolysis liquid in heat preservation 4-8 hours, and enzymolysis liquid is warming up to 90-95 DEG C and is gone out within heat preservation 10-20 minutes at 90-95 DEG C Then enzymolysis liquid after enzyme deactivation activity is centrifuged, removes precipitating by enzymatic activity, will be centrifuged obtained liquid and cross 300 meshes, and retain filter The pH value of filtrate is adjusted to 4-5 with the sodium hydrate aqueous solution of the hydrochloric acid solution of 1-5mol/L and 1-5mol/L by liquid, again from The heart, the precipitating after taking centrifugation obtain extracting from the flavor peptide of chicken bone after being dried in vacuo 3-8h at 30-50 DEG C.
The processing method of the flavor peptide for extracting from Pleurotus eryngii are as follows: Pleurotus eryngii be crushed into 200 meshes, take 200-400g In the water that Pleurotus eryngii powder is added to 400-800g, temperature is 50-70 DEG C, 0.5-1.5g flavor is added after stirring 30-60 minutes Protease, 1-3g alkali protease, 0.3-0.5g cellulase, 0.2-0.8g neutral proteinase continue in temperature to be 50-70 DEG C Stop stirring after stirring 10-20 minutes, obtains enzymolysis liquid within heat preservation 5-10 hours at 50-70 DEG C, enzymolysis liquid is warming up to 90-95 DEG C And in the 90-95 DEG C of heat preservation activity of enzyme deactivation in 10-20 minutes, it is then centrifuged for, removes precipitating, the liquid that centrifugation obtains is crossed into 300 meshes, Retain filtrate, the pH value of filtrate is adjusted to 4.2- with the sodium hydrate aqueous solution of the hydrochloric acid solution of 1-5mol/L and 1-5mol/L 5.2, it is centrifuged again, the precipitating after taking centrifugation, obtains extracting from the flavor peptide of Pleurotus eryngii after being dried in vacuo 3-8h at 40-60 DEG C.
The processing method of the flavor peptide for extracting from fish-bone are as follows: fish-bone be crushed into 200 meshes, take 200-500g fish-bone In the water that powder is added to 400-1000g, temperature is 50-65 DEG C, 0.5-1.5g flavor albumen is added after stirring 30-50 minutes Enzyme, 1.5-3g alkali protease, 0.2-0.8g parts of neutral proteinases, continue to be 50-65 DEG C in temperature to stop after stirring 10-20 minutes It only stirs, obtains enzymolysis liquid within heat preservation 5-10 hours at 50-65 DEG C, enzymolysis liquid is warming up to 90-95 DEG C and is kept the temperature at 90-95 DEG C The activity of enzyme deactivation in 10-20 minutes, is then centrifuged for, removes precipitating, and the liquid that centrifugation obtains is crossed 300 meshes, retains filtrate, uses 1- The pH value of filtrate is adjusted to 3.6-4.7 by the hydrochloric acid solution of 5mol/L and the sodium hydrate aqueous solution of 1-5mol/L, is centrifuged again, Precipitating after taking centrifugation obtains extracting from the flavor peptide of fish-bone after being dried in vacuo 3-5h at 40-60 DEG C.
It is further preferred that the flavor peptide is to extract from the flavor peptide of chicken bone and extract from the flavor peptide of Pleurotus eryngii by matter Amount is than being (1-2): the mixture of (3-5).
A kind of processing method for subtracting anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower, weighs each original by weight Each raw material is uniformly mixed to obtain the final product by material.
The invention also discloses the above-mentioned anti-feed addictives that subtracts containing Radix Astragali or Radix Astragali stem, leaf, flower to subtract anti-feeding in preparation Application in material.
Concrete application is as follows:
It is a kind of subtract anti-feed by basal feed and it is above-mentioned containing Radix Astragali or Radix Astragali stem, leaf, flower subtract anti-feed addictive by Mass ratio 100:(2~5) it mixes;The composition of the basal feed is by mass percentage are as follows: corn 55~65%, wheat 5 ~9%, soybean oil 1~3%, dregs of beans 20~30%, PURE WHEY 2~4%, L-lysine 0.2~0.5%, calcium monohydrogen phosphate 1 ~3%, salt 0.1~0.3%.
The beneficial effect for subtracting anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower of the invention is: the Radix Astragali contained Ingredient has effects that improve immunity of livestock, improves disease resistance, of the invention to subtract anti-feeding containing Radix Astragali or Radix Astragali stem, leaf, flower Feed additives do not contain antibiotic and hormone medicine, non-hazardous to livestock and poultry and environment, are added in the common diet feed of livestock and poultry The nutrient content of feed can be improved, feed palatability is good, and digestibility is high, and feeding livestock and poultry can improve the speed of growth and breeding energy Power reduces diarrhea rate and the death rate.
On the basis of common knowledge of the art, above-mentioned each optimum condition, can be each preferably to get the present invention in any combination Embodiment.
Specific embodiment
The present invention is further illustrated below by the mode of embodiment, but does not therefore limit the present invention to the reality It applies among a range.In the following examples, the experimental methods for specific conditions are not specified, according to conventional methods and conditions, or according to quotient The selection of product specification.
In following embodiments, primary raw material and instrument used are as follows:
Astragalus root is leguminous mongolian scutellaria Astragalus membranaceus Bge.var.mongholicus (Bge.) dry root of Hsiao, Radix Astragali stem, Folium Astragali, Astragalis flower are leguminous mongolian scutellaria Astragalus Fresh stem, leaf, the flower of membranaceus Bge.var.mongholicus (Bge.) Hsiao, picks up from Bei Tian protozoa section The Shangdu County astragalus cultivation base of skill Co., Ltd.
Semen sojae atricolor is the black seeds of legume soybean (scientific name: Glycinemax (L.) merr), and having, which reduces gallbladder, consolidates Alcohol, kidney tonifying, the effect for improving anaemia.Place of production Heilungkiang.
Jujube also known as jujube, belong to Angiospermae, Dicotyledoneae, Rhamnales, Rhamnaceae, zizyphus plant, contain There are the nutritions abundant such as protein, carbohydrate, organic acid, vitamin A, vitamin C, lot of trace calcium and amino acid, has It is improved immunity, inhibits cancer cell.Place of production Zaozhuang, Shandong.
Pumpkin, Curcurbitaceae Cucurbita pumpkin kind pumpkin (Classification system: Cucurbita moschata (Duch.ex Lam.) Duch.ex Poiret) seed, have effects that it is hypoglycemic, anti-cancer, place of production Shaanxi.
Kelp, Phaeophyceae, Laminariaceae, Classification system: Laminaria japonica, the minerals member such as iodine rich in Element has reducing blood lipid blood glucose, adjusts a variety of biological functions such as immune, antitumor.Place of production Fujian.
Eggshell, the eggshell of specifically used thin and small hen.
Methionine, No. CAS: 63-68-3, it buys from Nanjing draft source Biotechnology Co., Ltd.
Zinc sulfate, No. CAS: 7733-02-0, it buys from the more food ingredient Co., Ltds in Jiangsu Cologne, food-grade.
Alfalfa meal, specifically used pulse family, clover category alfalfa (Classification system: Medicago sativa.) powder, purchase Reveal edible agricultural product Co., Ltd, 100 mesh of partial size, place of production Zhejiang from Shaoxin City's Shangyu area perseverance.
Root of kirilow rhodiola is Crassulaceae rhodiola (Classification system: Rhodiola crenulata (HK.f.et.Thoms) H.Ohba dry root) has the effect of qi and activate blood circulation, promotes blood circulation and relievings asthma.Place of production Jilin.
1,4 beta-glucanase, Ningxia Sunson Industrial Group Co., Ltd. is at production, 140,000 u/g of enzyme activity.
Zytase is bought from the rich and smooth auspicious Biotechnology Co., Ltd in Zhengzhou, 50,000 u/g of enzyme activity.
Soyabean oligosaccharides buy Anze Biotechnology Co., Ltd of nation westerly, model: zbsw2126.
Inulin, No. CAS: 9005-80-5, it buys from Shenzhen Biotechnology Co., Ltd of Hang Seng.
Arabogalactan, No. CAS: 9036-66-2, it buys from Zhejiang oasis Bioisystech Co., Ltd, model AA.
Ethyl alcohol, the ethanol water that the mass fraction of purchase from Changzhou inspiration Chemical Co., Ltd. is 95%, food-grade, The ethanol water of corrresponding quality score is diluted to when use.
Chicken bone, the chicken bone of specifically used thin and small hen.
Flavor protease is bought from Zhengzhou Jun Kai chemical products Co., Ltd, 100,000 u/g of enzyme activity.
Alkali protease, purchase is from Ningxia Sunson Industrial Group Co., Ltd. at production, 200,000 u/g of enzyme activity.
Hydrochloric acid, purchase is from Anhui Xing Xin Chemical Industry Science Co., Ltd, mass fraction 31%, when use be diluted to needed for it is dense Degree.
Sodium hydroxide, No. CAS: 1310-73-2, it buys from Kunshan Hui Er crowd Chemical Co., Ltd..
Pleurotus eryngii, Agaricales, Pleurotaceae, Pleurotus, Pleurotus eryngii kind, place of production Gutian Area, Fujian Province.
Cellulase, purchase is from Ningxia Sunson Industrial Group Co., Ltd. at production, enzyme activity 11000u/g
Neutral proteinase, purchase is from Ningxia Sunson Industrial Group Co., Ltd. at production, 60,000 u/g of enzyme activity.
Fish-bone, the fish-bone of carp (Classification system Cyprinus carpio).
In following embodiments, used test method and key instrument are as follows:
Growth of suckling pigs performance test:
Embodiment 1-10 and comparative example 1 are added to containing the anti-feed addictive that subtracts of Radix Astragali or Radix Astragali stem, leaf, flower respectively In sucking pig basal diet, it is uniformly mixed and obtains subtracting anti-feed containing Radix Astragali.The anti-feed that subtracts containing Radix Astragali or Radix Astragali stem, leaf, flower adds The mass ratio of the additive amount and basal feed that add agent is 3.5:96.5.For.The composition of basal feed is by mass percentage are as follows: corn 60.5%, wheat 7.25%, soybean oil 1.5%, dregs of beans 26%, PURE WHEY 3%, L-lysine 0.3%, calcium monohydrogen phosphate 1.3%, salt 0.15%.
The Landrace that age in days is 25 days is chosen, is divided into 12 groups, every group sucking pig 100.1-11 group is experimental group, respectively with real The anti-feed that subtracts containing Radix Astragali for applying a 1-10 and comparative example 1 is fed, and 12 groups are control group, is fed with sucking pig basal diet.Each group Sucking pig is managed according to pig farm conventinal breeding system, is raised by fixed laboratory technician, every the sky consistent in the hope of management condition Noon 7:00 and 4:00 in afternoon are fed.Free water is freely eaten.The environmental conditions such as ventilation, temperature, humidity in pig house are protected It holds unanimously, pig house drying, health is kept simultaneously periodically to sterilize.
The growth of suckling pigs performance of each group is tested, is weighed daily since when raising 20 days, and it is daily to start statistics Feed consumption, until raising 30 days when, terminate raising.Calculation formula is as follows:
Average daily gain=(average end weight-average starting weight)/test number of days;
Diarrhea rate=(diarrhea sucking pig head number × Diarrhoea days) ÷ (sucking pig head number × test number of days) × 100%.Test knot Fruit carries out statistical analysis, P < 0.05, and difference has statistical significance.
Total number of molds test:
Embodiment 1-10 and comparative example 1 are added to containing the anti-feed addictive that subtracts of Radix Astragali or Radix Astragali stem, leaf, flower respectively In sucking pig basal diet, it is uniformly mixed and obtains subtracting anti-feed containing Radix Astragali.The anti-feed that subtracts containing Radix Astragali or Radix Astragali stem, leaf, flower adds The mass ratio of the additive amount and basal feed that add agent is 3.5:96.5.The composition of basal feed is by mass percentage are as follows: corn 60.5%, wheat 7.25%, soybean oil 1.5%, dregs of beans 26%, PURE WHEY 3%, L-lysine 0.3%, calcium monohydrogen phosphate 1.3%, salt 0.15%.
It takes and subtracts 500 grams of anti-feed containing Radix Astragali, pack sealing is placed in the chamber of 30 DEG C of temperature, relative humidity 75% It saves.It stores the 60th day and is sampled, measure feed according to standard " measurement of total number of molds in GB/T 13092-2006 feed " Middle total number of molds.Sucking pig basal diet 500g separately is taken, tests total number of molds according to the method described above.
The present invention is further illustrated below by the mode of embodiment, and unless otherwise specified, used number is attached most importance to Measure number.
Embodiment 1
Subtract anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower, the raw material including following weight parts:
5 parts of astragalus membranaceus powders, 3 parts of black bean powders, 1.5 parts of jujube powders, 2 parts of pumpkin seed powders, 5 parts of Kelp Powders, 0.5 part of egg-shell meal, 0.02 part of methionine, 0.01 part of zinc sulfate, 30 parts of alfalfa meals.Alfalfa meal is commercially available alfalfa juice powder.
By astragalus root, semen sojae atricolor, the jujube of stoning, pumpkin, kelp, eggshell after 40 DEG C 6 hours dry, after crushing respectively It sieves with 100 mesh sieve, obtains astragalus membranaceus powder, black bean powder, jujube powder, pumpkin seed powder, Kelp Powder, egg-shell meal.Alfalfa meal is commercially available pale reddish brown Alfalfa meal.
It is as follows containing Radix Astragali or Radix Astragali stem, leaf, the processing method for subtracting anti-feed addictive of flower:
Each raw material is weighed by weight, is uniformly mixed and to be obtained subtracting anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower.
Embodiment 2
Subtract anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower, the raw material including following weight parts:
5 parts of astragalus membranaceus powders, 3 parts of black bean powders, 1.5 parts of jujube powders, 2 parts of pumpkin seed powders, 5 parts of Kelp Powders, 0.5 part of egg-shell meal, 0.02 part of methionine, 0.01 part of zinc sulfate, 30 parts of alfalfa meals.
By semen sojae atricolor, the jujube of stoning, pumpkin, kelp, eggshell after 40 DEG C 6 hours dry, 100 mesh are smashed it through respectively Sieve, obtains black bean powder, jujube powder, pumpkin seed powder, Kelp Powder, egg-shell meal.Alfalfa meal is commercially available alfalfa juice powder.By Radix Astragali Stem, Folium Astragali, Astragalis flower smash it through 100 meshes, then by Radix Astragali stem, Folium Astragali, Huang after 40 DEG C 6 hours dry respectively The powder of stilbene flower is uniformly mixed according to mass ratio for 1:1:1, obtains astragalus membranaceus powder.
It is as follows containing Radix Astragali or Radix Astragali stem, leaf, the processing method for subtracting anti-feed addictive of flower:
Each raw material is weighed by weight, is uniformly mixed and to be obtained subtracting anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower.
Embodiment 3
Subtract anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower, the raw material including following weight parts:
5 parts of astragalus membranaceus powders, 3 parts of semen sojae atricolor ferment powders, 1.5 parts of jujube powders, 2 parts of pumpkin seed powders, 5 parts of Kelp Powders, 0.5 part of eggshell Powder, 0.02 part of methionine, 0.01 part of zinc sulfate, 30 parts of alfalfa meals.
By astragalus root, the jujube of stoning, pumpkin, kelp, eggshell after 40 DEG C 6 hours dry, 100 are smashed it through respectively Mesh obtains astragalus membranaceus powder, black bean powder, jujube powder, pumpkin seed powder, Kelp Powder, egg-shell meal.Alfalfa meal is commercially available alfalfa Powder.
The semen sojae atricolor ferment powder the preparation method is as follows: it is 60 centimetres that black bean powder, which is paved into diameter, with a thickness of the cake of 5cm, It is steamed 40 minutes with 120 DEG C of vapor, takes 50g black bean powder to be added in 100g water after natural cooling, add 0.2g β-Portugal After mixing, enzymatic hydrolysis obtains mixture A in 120 minutes under conditions of temperature is 45 DEG C for dextranase, 0.5g zytase, to mixed It closes and 2 parts of sugar sources is added in object A, be 50 DEG C in temperature and be sealed by fermentation 72 hours, be then 30 DEG C in temperature and be sealed by fermentation 12 hours Mixture B is obtained, mixture B is placed 10 minutes in 110 DEG C of baking oven and is sterilized, it is then small in 35 DEG C of vacuum drying 24 When, obtain semen sojae atricolor ferment powder;The sugar source is soyabean oligosaccharides.
It is as follows containing Radix Astragali or Radix Astragali stem, leaf, the processing method for subtracting anti-feed addictive of flower:
Each raw material is weighed by weight, is uniformly mixed and to be obtained subtracting anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower.
Embodiment 4
Substantially the same manner as Example 3, difference is only that: sugar source described in the present embodiment 4 is inulin.
Embodiment 5
Substantially the same manner as Example 3, difference is only that: sugar source described in the present embodiment 5 is arabogalactan.
Embodiment 6
Subtract anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower, the raw material including following weight parts:
5 parts of astragalus membranaceus powders, 3 parts of semen sojae atricolor ferment powders, 1.5 parts of jujube powders, 2 parts of pumpkin seed powders, 1.8 parts of gadol extracts, 5 parts Kelp Powder, 0.5 part of egg-shell meal, 0.02 part of methionine, 0.01 part of zinc sulfate, 30 parts of alfalfa meals.
By astragalus root, semen sojae atricolor, the jujube of stoning, pumpkin, kelp, eggshell after 40 DEG C 6 hours dry, after crushing respectively It sieves with 100 mesh sieve, obtains astragalus membranaceus powder, black bean powder, jujube powder, pumpkin seed powder, Kelp Powder, egg-shell meal.Alfalfa meal is commercially available pale reddish brown Alfalfa meal.
The semen sojae atricolor ferment powder the preparation method is as follows: it is 60 centimetres that black bean powder, which is paved into diameter, with a thickness of the cake of 5cm, It is steamed 40 minutes with 120 DEG C of vapor, takes 50g black bean powder to be added in 100g water after natural cooling, add 0.2g β-Portugal After mixing, enzymatic hydrolysis obtains mixture A in 120 minutes under conditions of temperature is 45 DEG C for dextranase, 0.5g zytase, to mixed It closes and 2 parts of sugar sources is added in object A, be 50 DEG C in temperature and be sealed by fermentation 72 hours, be then 30 DEG C in temperature and be sealed by fermentation 12 hours Mixture B is obtained, mixture B is placed 10 minutes in 110 DEG C of baking oven and is sterilized, it is then small in 35 DEG C of vacuum drying 24 When, obtain semen sojae atricolor ferment powder;The sugar source is arabogalactan.
The gadol extract the preparation method is as follows: root of kirilow rhodiola is smashed it through 100 meshes, take root of kirilow rhodiola powder 30g is added in the ethanol water that 350g mass fraction is 30%, in the condition that temperature is 70 DEG C, revolving speed is 300 revs/min Lower stirring 24 hours, crosses 200 meshes, obtains first-time filtrate and filter residue, and filter residue is added to the second that 100g mass fraction is 45% It in alcohol solution, is stirred 5 hours under conditions of temperature is 70 DEG C, revolving speed is 300 revs/min, crosses 200 meshes, obtain secondary Filtrate, merges filtrate twice, and thick paste is by the thick paste that relative density is 1.6 when heating evaporation is concentrated into 50 DEG C of measurement in temperature 55 DEG C, vacuum degree be 0.06MPa under conditions of dry 3 hours, obtain gadol extract.
It is as follows containing Radix Astragali or Radix Astragali stem, leaf, the processing method for subtracting anti-feed addictive of flower:
Each raw material is weighed by weight, is uniformly mixed and to be obtained subtracting anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower.
Embodiment 7
Subtract anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower, the raw material including following weight parts:
5 parts of astragalus membranaceus powders, 3 parts of semen sojae atricolor ferment powders, 1.5 parts of jujube powders, 2 parts of pumpkin seed powders, 1.8 parts of gadol extracts, 5 parts Kelp Powder, 0.5 part of egg-shell meal, 0.02 part of methionine, 0.01 part of zinc sulfate, 30 parts of alfalfa meals, 1 part of flavor peptide.
By astragalus root, semen sojae atricolor, the jujube of stoning, pumpkin, kelp, eggshell after 40 DEG C 6 hours dry, after crushing respectively It sieves with 100 mesh sieve, obtains astragalus membranaceus powder, black bean powder, jujube powder, pumpkin seed powder, Kelp Powder, egg-shell meal.Alfalfa meal is commercially available pale reddish brown Alfalfa meal.
The semen sojae atricolor ferment powder the preparation method is as follows: it is 60 centimetres that black bean powder, which is paved into diameter, with a thickness of the cake of 5cm, It is steamed 40 minutes with 120 DEG C of vapor, takes 50g black bean powder to be added in 100g water after natural cooling, add 0.2g β-Portugal After mixing, enzymatic hydrolysis obtains mixture A in 120 minutes under conditions of temperature is 45 DEG C for dextranase, 0.5g zytase, to mixed It closes and 2 parts of sugar sources is added in object A, be 50 DEG C in temperature and be sealed by fermentation 72 hours, be then 30 DEG C in temperature and be sealed by fermentation 12 hours Mixture B is obtained, mixture B is placed 10 minutes in 110 DEG C of baking oven and is sterilized, it is then small in 35 DEG C of vacuum drying 24 When, obtain semen sojae atricolor ferment powder;The sugar source is arabogalactan.
The gadol extract the preparation method is as follows: root of kirilow rhodiola is smashed it through 100 meshes, take root of kirilow rhodiola powder 30g is added in the ethanol water that 350g mass fraction is 30%, in the condition that temperature is 70 DEG C, revolving speed is 300 revs/min Lower stirring 24 hours, crosses 200 meshes, obtains first-time filtrate and filter residue, and filter residue is added to the second that 100g mass fraction is 45% It in alcohol solution, is stirred 5 hours under conditions of temperature is 70 DEG C, revolving speed is 300 revs/min, crosses 200 meshes, obtain secondary Filtrate, merges filtrate twice, and thick paste is by the thick paste that relative density is 1.6 when heating evaporation is concentrated into 50 DEG C of measurement in temperature 55 DEG C, vacuum degree be 0.06MPa under conditions of dry 3 hours, obtain gadol extract.
The flavor peptide extracts from chicken bone, the processing method of the flavor peptide for extracting from chicken bone are as follows: by chicken bone surface Meat reject and with water by surface washing it is clean after, crushed 200 meshes after dry 6 hours at 40 DEG C, obtain chick bone powder, take 200g Chick bone powder 250g boiling is boiled simultaneously constantly boiling 10 minutes, crosses 200 meshes while hot, retains filter residue, and rushed with 150g, 50 DEG C of water Filter wash slag surface, drains the moisture on filter residue surface, filter residue is added to 200g, temperature is in 50 DEG C of water, with 50 revs/min 1g flavor protease, 1g alkali protease is added after stirring 30 minutes in revolving speed, continues in temperature to be 50 DEG C, with 50 revs/min Revolving speed stirring stops stirring after ten minutes, keeps the temperature 4 hours at 50 DEG C and obtains enzymolysis liquid, by enzymolysis liquid with the speed liter of 5 DEG C/min Temperature is to 90 DEG C and in 90 DEG C of heat preservations, 10 minutes enzyme deactivation activity, then by the enzymolysis liquid after enzyme deactivation activity with 3000 revs/min of turn Speed centrifugation 40 minutes, removes precipitating, and the obtained liquid of centrifugation is crossed 300 meshes, retains filtrate, with the hydrochloric acid solution of 1mol/L with The pH value of filtrate is adjusted to 4 by the sodium hydrate aqueous solution of 1mol/L, is then centrifuged 40 minutes with 8000 revs/min of revolving speed, Precipitating after taking centrifugation obtains extracting from the flavor peptide of chicken bone after being dried in vacuo 3h at 40 DEG C.
It is as follows containing Radix Astragali or Radix Astragali stem, leaf, the processing method for subtracting anti-feed addictive of flower:
Each raw material is weighed by weight, is uniformly mixed and to be obtained subtracting anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower.
Embodiment 8
Substantially the same manner as Example 7, difference is only that: flavor peptide described in the present embodiment 8 extracts from Pleurotus eryngii.It is described to mention It is derived from the processing method of the flavor peptide of Pleurotus eryngii are as follows: Pleurotus eryngii be crushed into 200 meshes, 200g Pleurotus eryngii powder is taken to be added to In 400g, the water that temperature is 50 DEG C, 0.5g flavor protease, 1g alkalinity are added after stirring 30 minutes with 50 revs/min of revolving speed Protease, 0.3g cellulase, 0.2g neutral proteinase continue to be 50 DEG C, stir 10 points with 50 revs/min of revolving speed in temperature Stop stirring after clock, kept the temperature at 50 DEG C and obtain enzymolysis liquid in 5 hours, by enzymolysis liquid with the speed of 5 DEG C/min be warming up to 90 DEG C and Then 90 DEG C of heat preservations, 10 minutes enzyme deactivation activity are centrifuged 40 minutes with 3000 revs/min of revolving speed, remove precipitating, centrifugation is obtained Liquid cross 300 meshes, retain filtrate, with the sodium hydrate aqueous solution of the hydrochloric acid solution of 1mol/L and 1mol/L by the pH of filtrate Value is adjusted to 4.2, is then centrifuged 40 minutes with 8000 revs/min of revolving speed, the precipitating after taking centrifugation, in 40 DEG C of vacuum drying 3h Obtain extracting from the flavor peptide of Pleurotus eryngii afterwards.
Embodiment 9
Substantially the same manner as Example 7, difference is only that: flavor peptide described in the present embodiment 9 extracts from fish-bone.The extraction From the processing method of the flavor peptide of fish-bone are as follows: fish-bone crushed 200 meshes, 200g fish-bone powder is taken to be added to 400g, temperature For in 50 DEG C of water, be added after being stirred 30 minutes with 50 revs/min of revolving speed 0.5g flavor protease, 1.5g alkali protease, 0.2g parts of neutral proteinases continue to be 50 DEG C, stop stirring after ten minutes with 50 revs/min of revolving speed stirring in temperature, 50 DEG C heat preservation obtains enzymolysis liquid in 5 hours, enzymolysis liquid with the speed of 5 DEG C/min is warming up to 90 DEG C and in 90 DEG C of heat preservations enzyme deactivation in 10 minutes Then activity is centrifuged 40 minutes with 3000 revs/min of revolving speed, removes precipitating, the liquid that centrifugation obtains is crossed 300 meshes, is protected The pH value of filtrate is adjusted to 4 with the sodium hydrate aqueous solution of the hydrochloric acid solution of 1mol/L and 1mol/L by reserved filtrate, then with 8000 revs/min of revolving speed is centrifuged 40 minutes, and the precipitating after taking centrifugation obtains extracting from fish-bone after 40 DEG C of vacuum drying 3h Flavor peptide.
Embodiment 10
Substantially the same manner as Example 7, difference is only that: flavor peptide described in the present embodiment 10 is the flavor for extracting from chicken bone Peptide and the flavor peptide for extracting from Pleurotus eryngii are the mixture of 2:3 in mass ratio.
The processing method of the flavor peptide for extracting from Pleurotus eryngii are as follows: Pleurotus eryngii be crushed into 200 meshes, take 200g apricot Bao In the water that mushroom powder end is added to 400g, temperature is 50 DEG C, 0.5g flavor egg is added after stirring 30 minutes with 50 revs/min of revolving speed White enzyme, 1g alkali protease, 0.3g cellulase, 0.2g neutral proteinase continue in temperature to be 50 DEG C, with 50 revs/min Revolving speed stirring stops stirring after ten minutes, keeps the temperature 5 hours at 50 DEG C and obtains enzymolysis liquid, by enzymolysis liquid with the speed liter of 5 DEG C/min Then temperature is centrifuged 40 minutes, it is heavy to remove to 90 DEG C and in 90 DEG C of heat preservations, 10 minutes enzyme deactivation activity with 3000 revs/min of revolving speed It forms sediment, the liquid that centrifugation obtains is crossed into 300 meshes, retains filtrate, with the hydrochloric acid solution of 1mol/L and the sodium hydroxide water of 1mol/L The pH value of filtrate is adjusted to 4.2 by solution, is then centrifuged 40 minutes with 8000 revs/min of revolving speed, the precipitating after taking centrifugation, Obtain extracting from the flavor peptide of Pleurotus eryngii after 40 DEG C of vacuum drying 3h.
The processing method of the flavor peptide for extracting from chicken bone are as follows: reject the meat of chicken bone surface and with water by surface washing After clean, it crushed 200 meshes after 6 hours dry at 40 DEG C, obtain chick bone powder, 200g chick bone powder 250g boiling is taken to boil and hold Continuous boiling 10 minutes, crosses 200 meshes while hot, retains filter residue, and rinse filter residue surface with 150g, 50 DEG C of water, drains filter residue table Filter residue is added to 200g, temperature to be added in 50 DEG C of water after stirring 30 minutes with 50 revs/min of revolving speed by the moisture in face 1g flavor protease, 1g alkali protease continue to be 50 DEG C, stop after ten minutes with 50 revs/min of revolving speed stirring in temperature Stirring keeps the temperature 4 hours at 50 DEG C and obtains enzymolysis liquid, and enzymolysis liquid is warming up to 90 DEG C with the speed of 5 DEG C/min and is kept the temperature at 90 DEG C Then enzymolysis liquid after enzyme deactivation activity is centrifuged 40 minutes by 10 minutes enzyme deactivation activity with 3000 revs/min of revolving speed, it is heavy to remove It forms sediment, the liquid that centrifugation obtains is crossed into 300 meshes, retains filtrate, with the hydrochloric acid solution of 1mol/L and the sodium hydroxide water of 1mol/L The pH value of filtrate is adjusted to 4 by solution, is then centrifuged 40 minutes with 8000 revs/min of revolving speed, the precipitating after taking centrifugation, 40 Obtain extracting from the flavor peptide of chicken bone after DEG C vacuum drying 3h.
Comparative example 1
Substantially the same manner as Example 3, difference is only that, semen sojae atricolor ferment powder described in this comparative example 1 the preparation method is as follows: will It is 60 centimetres that black bean powder, which is paved into diameter, with a thickness of the cake of 5cm, is steamed 40 minutes with 120 DEG C of vapor, is taken after natural cooling 50g black bean powder is added in 100g water, adds 0.2g 1,4 beta-glucanase, 0.5g zytase after mixing, is in temperature It is digested 120 minutes under conditions of 45 DEG C and obtains mixture C, mixture C is 50 DEG C in temperature and is sealed by fermentation 72 hours, is then existed Temperature is that 30 DEG C of sealing and fermentings obtain mixture D in 12 hours, and mixture D is placed 10 minutes in 110 DEG C of baking oven and is killed Then bacterium is dried in vacuo 24 hours at 35 DEG C, obtains semen sojae atricolor ferment powder.
Measure of merit example 1
The sucking pig for subtracting anti-feed to feeding containing Radix Astragali carries out growth performance test, and test result is shown in Table 1.
Table 1: growth of suckling pigs the performance test results table
It is of the invention to subtract anti-feed addictive without antibiotic, full of nutrition, digestion containing Radix Astragali or Radix Astragali stem, leaf, flower Absorptivity is high, is added in common daily ration, can improve the immunity of livestock and poultry, reduces diarrhea, dead probability of happening.With embodiment 1-2 is compared, and embodiment 3-5's has used in anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, subtracting for flower by black bean powder fermentation production Raw semen sojae atricolor ferment powder, the fermentation of semen sojae atricolor ferment powder generate multiple active enzymes and probiotics, have adjustment sucking pig stomach, eliminate just Secret, promotion absorption and other effects, improves the daily gain of sucking pig, reduces diarrhea rate.Compared with comparative example 1, embodiment 3-5 is to hair Sugar source used in ferment process has carried out preferably, the results showed that the semen sojae atricolor ferment to ferment using arabogalactan as sugar source Plain powder promotes digestion and absorption effect more preferable.Embodiment 6 contains containing Radix Astragali or Radix Astragali stem, leaf, subtracting in anti-feed addictive for flower Gadol extract, gadol extract have the function of antifungi, antifatigue, strengthen immunity, can be reduced the morbidity machine of pig Meeting.Embodiment 7-10 containing Radix Astragali or Radix Astragali stem, leaf, flower subtract in anti-feed addictive containing extract from chicken bone, Pleurotus eryngii or The flavor peptide of fish-bone, flavor peptide are the class proteins that can generate delicate flavour, can improve a poor appetite, improve small growth speed of pigs, in addition, It has also been found that the flavor peptide for extracting from chicken bone, Pleurotus eryngii or fish-bone can also improve the immunity of pig, anti-inflammatory effect, can drop The diarrhea rate of low pig.
Measure of merit example 2
Total number of molds test is carried out to the anti-feed that subtracts containing Radix Astragali, test result is shown in Table 2.
Table 2: total number of molds test result table
Nerve and endocrine disturbance, immunosupress, carcinogenic teratogenesis, lesions of liver and kidney, breeding when mycotoxin has livestock and poultry The harm such as obstacle.Have containing Radix Astragali or Radix Astragali stem, leaf, the gadol extract of flower subtracted in anti-feed addictive and flavor peptide good Good antifungi effect subtracts of the invention after anti-feed addictive mixes with common daily ration containing Radix Astragali or Radix Astragali stem, leaf, flower Have the effect of extending the storage time of feed, improves efficiency of feed utilization, reduces livestock and poultry illness.
The preferred embodiment of the present invention has been described in detail above.It should be appreciated that those skilled in the art without It needs creative work according to the present invention can conceive and makes many modifications and variations.Therefore, all technologies in the art Personnel are available by logical analysis, reasoning, or a limited experiment on the basis of existing technology under this invention's idea Technical solution, all should be within the scope of protection determined by the claims.

Claims (7)

1. a kind of subtract anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower, which is characterized in that the original including following weight parts Material:
5-10 parts of astragalus membranaceus powders, 3-5 parts of black bean powders, 1-3 parts of jujube powders, 2-4 parts of pumpkin seed powders, 5-8 parts of Kelp Powders, 0.5-1.5 parts Egg-shell meal, 0.02-0.04 part methionine, 0.01-0.03 parts of zinc sulfate, 30-50 parts of alfalfa meals;The astragalus membranaceus powder is by Radix Astragali One of root, stem, leaf or flower or a variety of powder obtained after drying, crushing.
2. a kind of subtract anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower, which is characterized in that the original including following weight parts Material:
5-10 parts of astragalus membranaceus powders, 3-5 parts of semen sojae atricolor ferment powders, 1-3 parts of jujube powders, 2-4 parts of pumpkin seed powders, 5-8 parts of Kelp Powders, 0.5- 1.5 parts of egg-shell meals, 0.02-0.04 parts of methionine, 0.01-0.03 parts of zinc sulfate, 30-50 parts of alfalfa meals;The astragalus membranaceus powder is will One of root, stem, leaf or flower of Radix Astragali or a variety of powder obtained after drying, crushing.
3. a kind of subtract anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower, which is characterized in that the original including following weight parts Material:
5-10 parts of astragalus membranaceus powders, 3-5 parts of semen sojae atricolor ferment powders, 1-3 parts of jujube powders, 2-4 parts of pumpkin seed powders, 1-3 parts of gadol extracts, 5-8 parts of Kelp Powders, 0.5-1.5 parts of egg-shell meals, 0.02-0.04 methionine, 0.01-0.03 parts of zinc sulfate, 30-50 parts of alfalfa meals; The astragalus membranaceus powder is by one of the root of Radix Astragali, stem, leaf or flower or a variety of powder obtained after drying, crushing.
4. a kind of subtract anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower, which is characterized in that the original including following weight parts Material:
5-10 parts of astragalus membranaceus powders, 3-5 parts of semen sojae atricolor ferment powders, 1-3 parts of jujube powders, 2-4 parts of pumpkin seed powders, 1-3 parts of gadol extracts, 5-8 parts of Kelp Powders, 0.5-1.5 parts of egg-shell meals, 0.02-0.04 methionine, 0.01-0.03 parts of zinc sulfate, 30-50 parts of alfalfa meals, 0.5-1.5 parts of flavor peptides;The astragalus membranaceus powder is by one of the root of Radix Astragali, stem, leaf or flower or a variety of after drying, the crushing The powder arrived.
5. subtracting anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower according to Claims 2 or 3 or 4, feature exists In, the semen sojae atricolor ferment powder the preparation method comprises the following steps: semen sojae atricolor after dry 6-12 hours, is smashed it through 100 meshes at 40-60 DEG C, Black bean powder is obtained, it is 60-80 centimetres that black bean powder, which is paved into diameter, with a thickness of the cake of 3-5cm, is steamed with 100-120 DEG C of vapor 40-80 minutes, 50-100g black bean powder is taken to be added in 100-150g water after natural cooling, adds 0.2-1g beta glucan After mixing, enzymatic hydrolysis is mixed for 120-180 minutes under conditions of temperature is 45-60 DEG C for enzyme, 0.5-1.5g zytase Object A, into mixture A be added 2-5 part sugar sources, temperature for 50-70 DEG C sealing and fermenting 72-108 hours, be then in temperature 30-40 DEG C obtains mixture B in sealing and fermenting 12-24 hours, and mixture B is placed 10-20 minutes in 90-110 DEG C of baking oven Sterilized, then 35-50 DEG C vacuum drying 24-48 hours, obtain semen sojae atricolor ferment powder;The sugar source be soyabean oligosaccharides, One of inulin, arabogalactan.
6. according to claim 3 or 4 subtract anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower, which is characterized in that The gadol extract the preparation method is as follows: root of kirilow rhodiola is smashed it through 100 meshes, take root of kirilow rhodiola powder 30-50g to be added In the ethanol water for being 30-50% to 350-700g mass fraction, stirring 24-36 is small under conditions of temperature is 60-80 DEG C When, 200 meshes are crossed, first-time filtrate and filter residue are obtained, filter residue is added to the ethanol water that 100-300g mass fraction is 45-65% It in solution, is stirred 5-8 hours under conditions of temperature is 70-85 DEG C, crosses 200 meshes, obtain secondary filtrate, merging is filtered twice Liquid, the thick paste that relative density is 1.3-1.6 when heating evaporation is concentrated into 50 DEG C of measurement are dried under reduced pressure the thick paste to obtain root of kirilow rhodiola and mention Take object.
7. a kind of processing method for subtracting anti-feed addictive containing Radix Astragali or Radix Astragali stem, leaf, flower, which is characterized in that by weight It weighs each raw material, each raw material is uniformly mixed to obtain the final product.
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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102232495A (en) * 2011-07-30 2011-11-09 韩沛 Astragalus ovine fattening feed additive
CN104432283A (en) * 2014-11-21 2015-03-25 山东东方海洋科技股份有限公司 High-calcium fishbone taste-active peptide nutrient soup base and preparation method thereof
CN105851530A (en) * 2016-04-12 2016-08-17 南京可莱威饲料有限公司 Rhodiola rosea extract-containing lactating sow premix and preparation method thereof
US20160249638A1 (en) * 2011-12-02 2016-09-01 Dast, Llc Dba Prairie Aquatech Microbial-Based Process for High Quality Protein Concentrate
CN107259134A (en) * 2017-08-08 2017-10-20 黄丽英 The preparation method of cattle and sheep ferment feed
CN107494911A (en) * 2017-09-06 2017-12-22 大兴安岭北天原生物科技有限责任公司 The flower containing membranous milkvetch stem and leaf subtracts anti-feed, the method without using antibiotic cultivated animals
CN107960548A (en) * 2018-01-03 2018-04-27 廊坊瑞康饲料有限公司 Digestant pannage

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102232495A (en) * 2011-07-30 2011-11-09 韩沛 Astragalus ovine fattening feed additive
US20160249638A1 (en) * 2011-12-02 2016-09-01 Dast, Llc Dba Prairie Aquatech Microbial-Based Process for High Quality Protein Concentrate
CN104432283A (en) * 2014-11-21 2015-03-25 山东东方海洋科技股份有限公司 High-calcium fishbone taste-active peptide nutrient soup base and preparation method thereof
CN105851530A (en) * 2016-04-12 2016-08-17 南京可莱威饲料有限公司 Rhodiola rosea extract-containing lactating sow premix and preparation method thereof
CN107259134A (en) * 2017-08-08 2017-10-20 黄丽英 The preparation method of cattle and sheep ferment feed
CN107494911A (en) * 2017-09-06 2017-12-22 大兴安岭北天原生物科技有限责任公司 The flower containing membranous milkvetch stem and leaf subtracts anti-feed, the method without using antibiotic cultivated animals
CN107960548A (en) * 2018-01-03 2018-04-27 廊坊瑞康饲料有限公司 Digestant pannage

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
SUN ET AL.: "Antioxidant, antitumor and immunostimulatory activities of thepolypeptide from Pleurotus eryngii mycelium", 《INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES》 *
李栋刚等: "生物活性肽在畜禽生产中的应用及发展前景", 《中国禽业导刊》 *
聂芙蓉等主编: "《饲料添加剂安全应用关键技术》", 30 September 2016, 中原农民出版社 *

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