CN109173870A - It is a kind of for producing the mixing kettle of Levetiracetam bulk pharmaceutical chemicals - Google Patents

It is a kind of for producing the mixing kettle of Levetiracetam bulk pharmaceutical chemicals Download PDF

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Publication number
CN109173870A
CN109173870A CN201811207564.7A CN201811207564A CN109173870A CN 109173870 A CN109173870 A CN 109173870A CN 201811207564 A CN201811207564 A CN 201811207564A CN 109173870 A CN109173870 A CN 109173870A
Authority
CN
China
Prior art keywords
autoclave body
producing
stirring plate
supporting element
pharmaceutical chemicals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811207564.7A
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Chinese (zh)
Inventor
王玉斌
张英
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanjing La Aifu Pharmaceutical Technology Co Ltd
Original Assignee
Nanjing La Aifu Pharmaceutical Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanjing La Aifu Pharmaceutical Technology Co Ltd filed Critical Nanjing La Aifu Pharmaceutical Technology Co Ltd
Priority to CN201811207564.7A priority Critical patent/CN109173870A/en
Publication of CN109173870A publication Critical patent/CN109173870A/en
Pending legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/44Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement
    • B01F31/443Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement performing a superposed additional movement other than oscillation, vibration or shaking
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/22Mixing of ingredients for pharmaceutical or medical compositions

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mixers Of The Rotary Stirring Type (AREA)

Abstract

The present invention provides a kind of for producing the mixing kettle of Levetiracetam bulk pharmaceutical chemicals, including autoclave body, two shafts are symmetrically arranged with along central axes direction in the middle part of autoclave body inner cavity, the outer end of two shafts is driven by motor, the middle part of autoclave body is equipped with supporting element, supporting element external circumferential direction is evenly equipped with connecting rod, and the inner end of two shafts is rotatably supported at respectively in the middle part of the left and right sides of supporting element, is threaded with stirring plate in shaft.The beneficial effects of the present invention are: overall structure is novel, it can control stirring plate bilateral reciprocation in one end of autoclave body by shaft, and since the intracorporal amount shaft of kettle is driven by motor respectively, so that the reciprocating rate back and forth of the stirring plate at autoclave body inner cavity both ends and direction can be controlled separately, the disorder degree of material in autoclave body is effectively increased, stirring efficiency is improved.

Description

It is a kind of for producing the mixing kettle of Levetiracetam bulk pharmaceutical chemicals
Technical field
The present invention relates to mixing kettle technical fields more particularly to a kind of for producing the mixing of Levetiracetam bulk pharmaceutical chemicals Kettle.
Background technique
Levetiracetam (Levetiracetam), it is one that alias is happy all for La Xitan, Li Weixitan, left-handed etiracetam The chemicals of kind white crystalline powder.Chemical name (S)-alpha-ethyl-2-oxo -1- pyrrolidine acetamide, molecular formula are C7H14N2O2, molecular weight 170.20800.Levetiracetam is antiepileptic, is clinically mainly used for adult and 4 years old or more The add-on of Patients with Epilepsy in Childhood partial seizures.Currently, existing mixing kettle mixed effect is bad, product quality is difficult to protect Card.
Summary of the invention
To solve the above problems, the invention discloses a kind of for producing the mixing kettle of Levetiracetam bulk pharmaceutical chemicals, effectively Mixing efficiency is improved, ensure that product quality.
In order to reach the goals above, the invention provides the following technical scheme:
It is a kind of for producing the mixing kettle of Levetiracetam bulk pharmaceutical chemicals, it is characterised in that: including autoclave body, the autoclave body sets for level The hollow columnar structures set, inner cavity middle part are symmetrically arranged with two shafts along central axes direction, and the outer end of two shafts can turn respectively In the middle part of the dynamic both ends for being supported on autoclave body, and the motor driven by being arranged in outside autoclave body end, the middle part of the autoclave body are equipped with branch Support member, the supporting element is in the disc-shaped structure being vertically arranged, and external circumferential direction is evenly equipped with connecting rod, one end of the connecting rod It is connect with supporting element, the inner wall connection of the other end and autoclave body, the inner end of two shafts is rotatably supported at a left side for supporting element respectively Right two middle side parts are threaded with stirring plate in the shaft, and the stirring plate is in discoid knot compatible with autoclave body inner cavity Structure is evenly equipped with card convex on external circumferential direction, is evenly equipped with discharge orifice on stirring plate, along its week on the inner wall of the autoclave body left and right ends It is evenly equipped with bar shaped sliding slot identical with card convex quantity to direction, the bar shaped sliding slot is arranged along the axis direction of autoclave body, and bar shaped Sliding slot is adapted with card convex.
Further, the shaft is equipped with external screw thread.
Further, it is equipped with through-hole compatible with shaft in the middle part of the stirring plate, and is equipped with and external screw thread phase in through-hole The internal screw thread of adaptation.
Further, the top and the bottom of described autoclave body one end are respectively equipped with inlet port and outlet port.
Further, the autoclave body bottom is equipped with support frame.
Compared with prior art, it is novel that the beneficial effects of the present invention are: overall structures, can control stirring plate by shaft The bilateral reciprocation in one end of autoclave body, and since the intracorporal amount shaft of kettle is driven by motor respectively, so that autoclave body The reciprocating rate back and forth of the stirring plate at inner cavity both ends and direction can be controlled separately, and effectively increase the disorder of material in autoclave body Degree improves stirring efficiency.
Detailed description of the invention
Fig. 1 is that the present invention is a kind of for producing the structural schematic diagram of the mixing kettle of Levetiracetam bulk pharmaceutical chemicals.
Fig. 2 is the side view of stirring plate in Fig. 1.
Reference signs list:
1- autoclave body, 2- shaft, 3- motor, 4- supporting element, 5- connecting rod, 6- stirring plate, 7- card convex, 8- bar shaped sliding slot.
Specific embodiment
With reference to the accompanying drawings and detailed description, the present invention is furture elucidated, it should be understood that following specific embodiments are only For illustrating the present invention rather than limiting the scope of the invention.
As shown, a kind of for producing the mixing kettle of Levetiracetam bulk pharmaceutical chemicals, including autoclave body 1, autoclave body 1 sets for level The hollow columnar structures set, inner cavity middle part are symmetrically arranged with two shafts 2 along central axes direction, and the outer end of two shafts 2 respectively can In the middle part of the both ends for being supported on autoclave body 1 of rotation, and the motor 3 by being arranged in outside 1 end of autoclave body drives, and the middle part of autoclave body 1 is equipped with Supporting element 4, supporting element 4 are in the disc-shaped structure that is vertically arranged, and external circumferential direction is evenly equipped with connecting rod 5, one end of connecting rod 5 with Supporting element 4 connects, and the other end is connect with the inner wall of autoclave body 1, and the inner end of two shafts 2 is rotatably supported at supporting element 4 respectively In the middle part of the left and right sides, stirring plate 6 is threaded in shaft 2, stirring plate 6 is in disc-shaped structure compatible with 1 inner cavity of autoclave body, It is evenly equipped with card convex 7 on its external circumferential direction, is evenly equipped with discharge orifice on stirring plate 6, along its circumferential direction side on 1 left and right ends inner wall of autoclave body To bar shaped sliding slot 8 identical with 7 quantity of card convex is evenly equipped with, bar shaped sliding slot 8 is arranged along the axis direction of autoclave body 1, and bar shaped sliding slot 8 It is adapted to card convex phase 7.
In the present embodiment, shaft 2 is equipped with external screw thread, and through-hole compatible with shaft 2 is equipped in the middle part of stirring plate 6, and Internal screw thread compatible with external screw thread is equipped in through-hole.
In the present embodiment, the top and the bottom of 1 one end of autoclave body are respectively equipped with inlet port and outlet port.
In the present embodiment, 1 bottom of autoclave body is equipped with support frame.
The present invention can control stirring plate bilateral reciprocation in one end of autoclave body by shaft, and since kettle is intracorporal Amount shaft is driven by motor respectively, so that the reciprocating rate back and forth of the stirring plate at autoclave body inner cavity both ends and direction can be divided It does not control, effectively increases the disorder degree of material in autoclave body, improve stirring efficiency.
The technical means disclosed in the embodiments of the present invention is not limited only to technological means disclosed in above embodiment, further includes Technical solution consisting of any combination of the above technical features.It should be pointed out that for those skilled in the art For, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications are also considered as Protection scope of the present invention.

Claims (5)

1. a kind of for producing the mixing kettle of Levetiracetam bulk pharmaceutical chemicals, it is characterised in that: including autoclave body (1), the autoclave body (1) For horizontally disposed hollow columnar structures, inner cavity middle part is symmetrically arranged with two shafts (2) along central axes direction, two shafts (2) Outer end be rotatably supported in the middle part of the both ends of autoclave body (1) respectively, and the motor (3) by being arranged in outside autoclave body (1) end drives Dynamic, the middle part of the autoclave body (1) is equipped with supporting element (4), and the supporting element (4) is in the disc-shaped structure being vertically arranged, and outside Circumferential direction is evenly equipped with connecting rod (5), and one end of the connecting rod (5) is connect with supporting element (4), the inner wall of the other end and autoclave body (1) Connection, the inner end of two shafts (2) are rotatably supported at respectively in the middle part of the left and right sides of supporting element (4), spiral shell on the shaft (2) Line is connected with stirring plate (6), and the stirring plate (6) is in disc-shaped structure compatible with autoclave body (1) inner cavity, external circumferential side It is evenly equipped with card convex (7) upwards, is evenly equipped with discharge orifice on stirring plate (6), along its circumferential direction on the inner wall of autoclave body (1) left and right ends It is evenly equipped with bar shaped sliding slot (8) identical with card convex (7) quantity, the bar shaped sliding slot (8) is arranged along the axis direction of autoclave body (1), And bar shaped sliding slot (8) is adapted to card convex phase (7).
2. according to claim 1 a kind of for producing the mixing kettle of Levetiracetam bulk pharmaceutical chemicals, it is characterised in that: described Shaft (2) is equipped with external screw thread.
3. according to claim 2 a kind of for producing the mixing kettle of Levetiracetam bulk pharmaceutical chemicals, it is characterised in that: described It is equipped with shaft (2) compatible through-hole in the middle part of stirring plate (6), and is equipped with internal screw thread compatible with external screw thread in through-hole.
4. according to claim 1 a kind of for producing the mixing kettle of Levetiracetam bulk pharmaceutical chemicals, it is characterised in that: described The top and the bottom of autoclave body (1) one end are respectively equipped with inlet port and outlet port.
5. according to claim 1 a kind of for producing the mixing kettle of Levetiracetam bulk pharmaceutical chemicals, it is characterised in that: described Autoclave body (1) bottom is equipped with support frame.
CN201811207564.7A 2018-10-17 2018-10-17 It is a kind of for producing the mixing kettle of Levetiracetam bulk pharmaceutical chemicals Pending CN109173870A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811207564.7A CN109173870A (en) 2018-10-17 2018-10-17 It is a kind of for producing the mixing kettle of Levetiracetam bulk pharmaceutical chemicals

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811207564.7A CN109173870A (en) 2018-10-17 2018-10-17 It is a kind of for producing the mixing kettle of Levetiracetam bulk pharmaceutical chemicals

Publications (1)

Publication Number Publication Date
CN109173870A true CN109173870A (en) 2019-01-11

Family

ID=64945569

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201811207564.7A Pending CN109173870A (en) 2018-10-17 2018-10-17 It is a kind of for producing the mixing kettle of Levetiracetam bulk pharmaceutical chemicals

Country Status (1)

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CN (1) CN109173870A (en)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1930787A1 (en) * 1969-06-18 1971-01-07 Ratomir Bogdanovic Mixing kneading meat dough pastes or plas- - tics
DE1782157A1 (en) * 1968-07-25 1971-07-29 Wilfried Baumann Device for mixing and purifying liquids and thin liquid materials
CN203874692U (en) * 2014-02-19 2014-10-15 赵济彦 Stirring device
CN104906983A (en) * 2015-06-18 2015-09-16 无锡恒诚硅业有限公司 White carbon black pulpifying stirrer
CN207430234U (en) * 2017-11-02 2018-06-01 丰城恒泰食品有限公司 A kind of agitating device for Maillard reaction kettle
CN108607449A (en) * 2018-04-04 2018-10-02 陈洁 A kind of chemical industry mixing plant
CN108607398A (en) * 2018-05-22 2018-10-02 芜湖致新信息科技有限公司 A kind of Textile Dyes blender stirred evenly

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1782157A1 (en) * 1968-07-25 1971-07-29 Wilfried Baumann Device for mixing and purifying liquids and thin liquid materials
DE1930787A1 (en) * 1969-06-18 1971-01-07 Ratomir Bogdanovic Mixing kneading meat dough pastes or plas- - tics
CN203874692U (en) * 2014-02-19 2014-10-15 赵济彦 Stirring device
CN104906983A (en) * 2015-06-18 2015-09-16 无锡恒诚硅业有限公司 White carbon black pulpifying stirrer
CN207430234U (en) * 2017-11-02 2018-06-01 丰城恒泰食品有限公司 A kind of agitating device for Maillard reaction kettle
CN108607449A (en) * 2018-04-04 2018-10-02 陈洁 A kind of chemical industry mixing plant
CN108607398A (en) * 2018-05-22 2018-10-02 芜湖致新信息科技有限公司 A kind of Textile Dyes blender stirred evenly

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SE01 Entry into force of request for substantive examination
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Application publication date: 20190111

RJ01 Rejection of invention patent application after publication