CN109107954A - A kind of board-washing device of optional ELISA Plate hole location cleaning - Google Patents

A kind of board-washing device of optional ELISA Plate hole location cleaning Download PDF

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Publication number
CN109107954A
CN109107954A CN201810929881.3A CN201810929881A CN109107954A CN 109107954 A CN109107954 A CN 109107954A CN 201810929881 A CN201810929881 A CN 201810929881A CN 109107954 A CN109107954 A CN 109107954A
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CN
China
Prior art keywords
board
washing
elisa plate
hole location
washing device
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Pending
Application number
CN201810929881.3A
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Chinese (zh)
Inventor
张立海
高海荣
邵伟
张猛
王晓凤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
YANTAI ADDCARE BIO-TECH Co Ltd
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YANTAI ADDCARE BIO-TECH Co Ltd
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Application filed by YANTAI ADDCARE BIO-TECH Co Ltd filed Critical YANTAI ADDCARE BIO-TECH Co Ltd
Priority to CN201810929881.3A priority Critical patent/CN109107954A/en
Publication of CN109107954A publication Critical patent/CN109107954A/en
Pending legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B3/00Cleaning by methods involving the use or presence of liquid or steam
    • B08B3/02Cleaning by the force of jets or sprays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B13/00Accessories or details of general applicability for machines or apparatus for cleaning

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  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The present invention discloses a kind of board-washing device of optional ELISA Plate hole location cleaning, board-washing device is used to clean the culture dish of ELISA Plate, board-washing device includes control mechanism and board-washing mechanism, the fluid path mechanism being connect with board-washing mechanism, board-washing device further includes propulsive mechanism, the load carrier being connect with propulsive mechanism, control mechanism is laid out the board-washing position for determining the propulsion stroke and board-washing mechanism of propulsive mechanism according to culture dish to be cleaned on ELISA Plate, propulsive mechanism makes load carrier according to propulsion stroke motion in the lower section of board-washing mechanism according to determining propulsion stroke, propulsive mechanism is also connected with testing agency, judge propulsive mechanism to the advance distance of load carrier by testing agency in progradation.The present invention carries out selection cleaning to the culture dish hole location arbitrarily arranged, realizes specific hole location cleaning, shortens the test experience time the step of typesetting perforations adding before machine in omission, reduce labor intensity, reduce the risk of corrupt data, prevent unnecessary waste, save testing cost.

Description

A kind of board-washing device of optional ELISA Plate hole location cleaning
Technical field
The present invention relates to a kind of board-washing devices, more particularly to a kind of board-washing device of optional ELISA Plate hole location cleaning.
Background technique
Board-washing machine is a kind of medical instrument for cleaning ELISA Plate, and general and microplate reader matches.Answer extensively For hospital, the ELISA Plate cleaning of blood station, health and epidemic prevention station, chemical reagent work, research department.Board-washing machine is using automatic enzyme immune Essential a kind of equipment in test experience.The hair washing of board-washing machine is conventional for cleaning there are commonly 8 needles, 12 needles, 96 needles 96 hole elisa Plates.The transverse direction and vertical single cleaning, 96 needles of 8 needles and 12 needles for ELISA Plate are cleaned for full plate.
ELISA Plate is usually made of culture dish and substrate two parts, has split type and two kinds of integral type, and split type is 96 Independent culture dish is by 8x12 arrangement insertion substrate, and culture dish is disposable product, and substrate can be recycled.Integral type is substrate With 96 culture dish position integrated injection moldings, two parts are inseparable.Currently, according to detection sample when using split type ELISA Plate Product quantity determines that, using culture dish quantity, sample size often can not just gather full permutation (8 or 12 multiples), when hole count not When sufficient, need manually to supply hole count to set solid, otherwise board-washing lower part does not have culture dish to accept washing lotion, it may appear that washing lotion is excessive, stream Enter board-washing machine internal phenomena, occurs hindering the accidents such as detection and damage machine.Prior art increases the labor of testing staff Fatigue resistance and working time, and the typesetting before upper machine can increase the probability of sample confusion, be easy to cause the inaccurate of experimental data Really, the culture dish of not sample can be cleaned after artificial perforations adding, washing lotion is caused to waste, increase testing cost.
The Chinese patent of Publication No. CN106423975A discloses a kind of automatic enzyme label washing plate, including casing, turntable, Rotary disc driving mechanism, turntable driving position-limit mechanism, cleaning head device, cleaning liquid supply unit, waste liquid recovery apparatus, cleaning head liter Falling unit, the cavity bottom of the casing are inclined design, and cover board is equipped with above the casing, is equipped with turntable in the casing, The casing side is equipped with rotary disc driving mechanism, is equipped with turntable below the rotary disc driving mechanism and drives position-limit mechanism, the machine Shell bottom is equipped with cleaning head device, is communicated with cleaning liquid supply unit on the left of the cleaning head device, under the cleaning head device Side is communicated with waste liquid recovery apparatus, and cleaning head lifting device is equipped with below the cleaning head device.Although the technical solution mentions High cleaning efficiency, but can not achieve the optional ELISA Plate hole location cleaning of technical scheme.There are still work as hole count When insufficient, the problem of manually supplying hole count to set solid is needed.
The Chinese patent of Publication No. CN106623205A discloses the quick board-washing machine of micro reaction plate and plate washing method, packet The box body and lid of sealed connection are included, the plate hole equipped with ELISA Plate placed cavity and corresponding ELISA Plate is provided with number ruler in lid Very little corresponding through-hole, the box body is interior to drain system equipped with ELISA Plate cleaning system and ELISA Plate;The ELISA Plate cleaning system Liquid source including cleaning sprayer corresponding with each through-hole and the cleaning solution being connected with cleaning sprayer, specifically, include clean plate, The clean plate upper surface be equipped with cleaning needle corresponding with the plate hole number size of ELISA Plate, the cleaning needle inner hollow, with The liquid source of external cleaning solution after the connection of clean plate bottom cavity;It includes being set on board-washing machine, even that the ELISA Plate, which drains system, The escape pipe of logical tray interior and the negative pressure source being connected with the escape pipe, the lid are equipped with pressure relief means thereon.The technical side Case master is to solve that reorganize and outfit overall volume big, is not easy to transition and carries;Residual moisture after cleaning tends not to complete rapidly Portion discharge, scavenging period is long, air-blowing featheriness can in system large batch of introducing outside air, reduce its sanitary grade problem. It equally can not achieve the optional ELISA Plate hole location cleaning of technical scheme.It is artificial there are still needing when hole count deficiency The problem of supplying hole count to set solid.
Summary of the invention
The present invention, can in view of the deficienciess of the prior art, provide a kind of board-washing device of optional ELISA Plate hole location cleaning To carry out selection cleaning to the culture dish hole location arbitrarily arranged, realizes specific hole location cleaning, the step of typesetting perforations adding before machine is omitted Suddenly, the test experience time is shortened, labor intensity is reduced, reduces the risk of corrupt data, has prevented unnecessary waste, Testing cost is saved.
The technical scheme to solve the above technical problems is that a kind of board-washing dress of optional ELISA Plate hole location cleaning It sets, the board-washing device is used to clean the culture dish of ELISA Plate, and board-washing device includes control mechanism and board-washing mechanism, is washed with described The fluid path mechanism of trigger structure connection, the board-washing device further includes propulsive mechanism, the load carrier connecting with the propulsive mechanism, The control mechanism determines the propulsion stroke of the propulsive mechanism according to culture dish layout to be cleaned on ELISA Plate and described washes The board-washing position of trigger structure, propulsive mechanism make the load carrier according to propulsion stroke motion in institute according to determining propulsion stroke The lower section of board-washing mechanism is stated, propulsive mechanism is also connected with testing agency, passes through described in testing agency judgement in progradation Advance distance of the propulsive mechanism to the load carrier.
The preferred embodiment of board-washing device as the cleaning of optional ELISA Plate hole location, the board-washing mechanism includes Z-direction elevator, Z-direction elevator top is connected with hanging plate, and the hanging plate side is connected with board-washing head, is connected with board-washing needle below board-washing head, Above the load carrier of the board-washing needle arrangement in the process of running.The hanging plate on Z-direction elevator top is used to connect board-washing head, together When by Z-direction elevator movement drive hanging plate lifting, and then realize board-washing head and board-washing needle lifting, board-washing needle include spray It penetrates cleaning solution and draws two column needles of waste liquid after cleaning, board-washing needle itself belongs to the prior art.
The preferred embodiment of board-washing device as the cleaning of optional ELISA Plate hole location, the Z-direction elevator middle part are prolonged to side It stretches to form driving portion, is connected with Z-direction driving motor below the driving portion, Z-direction driving motor side is connected with Z-direction motor and fixes Seat, Z-direction elevator inside are connected with Z-direction riser guide, and Z-direction riser guide is connect with Z-direction motor fixing seat side.Z-direction Driving motor realizes that the lifting of driving portion, the lifting of driving portion make Z-direction elevator above and below Z-direction riser guide by motor polished rod It is mobile, and then guarantee the accuracy of Z-direction elevator.
The preferred embodiment of board-washing device as the cleaning of optional ELISA Plate hole location, the load carrier includes ELISA Plate seat, ELISA Plate seat upper end is formed with ELISA Plate slot, is connected on the inside of ELISA Plate seat and shelves slot, shelves slot outside and the propulsive mechanism Connection.ELISA Plate seat places ELISA Plate substrate to be cleaned by ELISA Plate slot, can place any position on ELISA Plate substrate Culture dish is cleaned by board-washing mechanism, and after board-washing device use, the board-washing needle of board-washing mechanism can be resetted in shelving In slot, facilitate next use, while preventing board-washing needle from polluting.
The preferred embodiment of board-washing device as the cleaning of optional ELISA Plate hole location, the propulsive mechanism includes slide bar, described Slide bar is connect on the outside of slot with described shelve, and slide bar and ELISA Plate seat lower part are equipped with slideway, and the slide bar drives the enzyme mark Panel seat is moved back and forth along the slideway, and press button mechanism is connected on the outside of slideway.Slide bar passes through stud connection with slot outside is shelved, Slide bar is able to drive ELISA Plate seat and moves along slideway, thus pass through ELISA Plate to be cleaned from the lower section of board-washing mechanism, slideway The press button mechanism in outside can choose the cleaning hole location of ELISA Plate, and board-washing mechanism is made only to clean specific hole location.Specific principle It is that testing agency is equipped with detection lug, detection lug passes through optoelectronic switch, and detection lug lower end is formed with stroke detection block, stroke detection The center spacing of block is identical as the spacing of two column culture dish adjacent on ELISA Plate to be detected.So as to accurate according to detection lug The hole location for determining cleaning controls the start and stop of board-washing mechanism by control mechanism using existing automated control technology.
The preferred embodiment of board-washing device as the cleaning of optional ELISA Plate hole location, the propulsive mechanism further include Y-direction movement Sliding rail, the slide bar end are downwardly extending Y-direction drive block, and Y-direction drive block side is connected with Y-direction movement sliding rail, Y-direction Drive block lower end is connected with Y-direction timing belt, and the Y-direction timing belt is connected with Y-direction driving motor;Prolong outward the slide bar end It stretches and crosses over the Y-direction movement sliding rail and form detection docking section.Y-direction driving motor drives Y-direction drive block fortune by Y-direction timing belt It is dynamic, so that slide bar be made to move, since testing agency connects with propulsive mechanism, it is synchronous with propulsive mechanism to can be realized testing agency Movement.
The top of the preferred embodiment of board-washing device as the cleaning of optional ELISA Plate hole location, the slide bar is equipped with middle vertical plate, Middle vertical plate lower end is formed with bar channel, and slide bar passes through the bar channel and connect on the outside of slot with described shelve, middle vertical plate upper end connection There is indication mechanism.Indication mechanism is shown for board-washing content and set interface, internal by control panel setting and adjustment parameter Be equipped with chip, setting instruction executed by chip, the driving Z-direction driving motor control lifting of board-washing head, board-washing needle on-off and ELISA Plate seat moves forward and backward.The control of indication mechanism and control panel belongs to the prior art.
The preferred embodiment of board-washing device as the cleaning of optional ELISA Plate hole location, the testing agency includes detection lug, inspection It surveys piece and passes through the optoelectronic switch for being connected to the propulsive mechanism, the detection lug lower end is formed with stroke detection block, the stroke The center spacing of detection block is identical as the spacing of two column culture dish adjacent on ELISA Plate to be detected.Stroke detection block is designed as sawing Dentation, and the center spacing of stroke detection block is identical as the spacing of two column culture dish adjacent on ELISA Plate to be detected, thus By stroke detection block to optoelectronic switch block realize stroke signal tally control, and then determine propulsive mechanism movement away from From.
The preferred embodiment of board-washing device as the cleaning of optional ELISA Plate hole location, the fluid path mechanism includes cleaning solution route With waste liquid circuit, solenoid valve, vacuum pump are connected separately on cleaning solution route and waste liquid circuit, cleaning solution route is connected with external Cleaning solution bucket, waste liquid circuit is connected with external waste liquid barrel.The company of cleaning solution route, waste liquid circuit and solenoid valve, vacuum pump It connects and belongs to the prior art, realize the on-off on board-washing first liquid road by cleaning solution route and waste liquid circuit, solenoid valve, vacuum pump open Stop being controlled according to the distance that hole location to be cleaned and detection lug determine, specific automation control belongs to the prior art.
The preferred embodiment of board-washing device as the cleaning of optional ELISA Plate hole location, the lower section of the load carrier, which is equipped with, to be accommodated Channel, the testing agency is under the drive of the propulsive mechanism in the receiving channel.Receiving channel is held in promotion The position of mounted mechanism simultaneously, enables testing agency in receiving channel.
Realize that structural feature of the invention is that detection lug lower end is formed with stroke detection block, between the center of stroke detection block Away from identical as the spacing of two column culture dish adjacent on ELISA Plate to be detected, pusher is judged by testing agency in progradation Structure is laid out according to culture dish to be cleaned on ELISA Plate to the advance distance of load carrier, control mechanism and determines pushing away for propulsive mechanism The board-washing position of journey and board-washing mechanism is carried out, propulsive mechanism makes load carrier according to propulsion stroke fortune according to determining propulsion stroke Move in the lower section of board-washing mechanism, the technology of the present invention thinking rely on structure disclosed in this invention, through the invention can be to appointing Meaning hole location carries out selection cleaning, can be configured on the control panel according to the hole location that cleaning is actually needed in test experience, leads to It crosses electrical control and realizes that the board-washing needle on board-washing head only carries out logical liquid to the corresponding hole site of setting, the hole location not set is broken Liquid realizes that specific hole location cleaning is reduced present invention omits the step of typesetting perforations adding, the test experience time is shortened before upper machine Labor intensity, reduces the risk of corrupt data, has prevented unnecessary waste, saved testing cost.
Detailed description of the invention
Fig. 1 is the board-washing device external structure schematic diagram of optional ELISA Plate hole location cleaning in embodiment;
Fig. 2 is the board-washing device schematic diagram of internal structure of optional ELISA Plate hole location cleaning in embodiment;
Fig. 3 is the schematic diagram of propulsive mechanism, load carrier, board-washing mechanism, load carrier and testing agency in embodiment;
Fig. 4 is propulsive mechanism, load carrier, board-washing mechanism, load carrier and the detection machine in embodiment under another visual angle The schematic diagram of structure;
Fig. 5 is the schematic diagram that emphasis shows propulsive mechanism, load carrier and board-washing mechanism in embodiment;
Fig. 6 is the board-washing device architecture schematic diagram of optional ELISA Plate hole location cleaning in embodiment;
Wherein, 1, control mechanism;2, board-washing mechanism;3, fluid path mechanism;4, propulsive mechanism;5, load carrier;6, detection machine Structure;7, Z-direction elevator;8, hanging plate;9, board-washing head;10, board-washing needle;11, driving portion;12, Z-direction driving motor;13, Z-direction motor Fixing seat;14, Z-direction riser guide;15, motor polished rod;16, ELISA Plate seat;17, ELISA Plate slot;18, slot is shelved;19, slide bar; 20, slideway;21, press button mechanism;22, hinged shaft;23, detection lug;24, stroke detection block;25, Y-direction moves sliding rail;26, Y-direction drives Block;27, Y-direction timing belt;28, Y-direction driving motor;29, docking section is detected;30, middle vertical plate;31, bar channel;32, indication mechanism; 33, cleaning solution route;34, waste liquid circuit;35, receiving channel;36, optoelectronic switch.
Specific embodiment
In order to make the foregoing objectives, features and advantages of the present invention clearer and more comprehensible, with reference to the accompanying drawing to the present invention Specific embodiment be described in detail.Many details are explained in the following description in order to fully understand this hair It is bright.But the invention can be embodied in many other ways as described herein, those skilled in the art can be not Similar improvement is done in the case where violating intension of the present invention, therefore the present invention is not limited by the specific embodiments disclosed below.
Unless otherwise defined, all technical and scientific terms used herein and belong to technical field of the invention The normally understood meaning of technical staff is identical.Term as used herein in the specification of the present invention is intended merely to description tool The purpose of the embodiment of body, it is not intended that in the limitation present invention.Term as used herein "and/or" includes one or more Any and all combinations of relevant listed item.
As shown in Figure 1, Figure 2, shown in Fig. 3, Fig. 4, Fig. 5 and Fig. 6, a kind of board-washing device of optional ELISA Plate hole location cleaning is described Board-washing device is used to clean the culture dish of ELISA Plate, and board-washing device includes control mechanism 1 and board-washing mechanism 2, with the board-washing machine The fluid path mechanism 3 that structure 2 connects, the board-washing device further includes propulsive mechanism 4, the load carrier connecting with the propulsive mechanism 4 5, the control mechanism 1 determines propulsion stroke and the institute of the propulsive mechanism 4 according to culture dish layout to be cleaned on ELISA Plate The board-washing position of board-washing mechanism 2 is stated, propulsive mechanism 4 makes the load carrier 5 according to propulsion stroke according to determining propulsion stroke It moves in the lower section of the board-washing mechanism 2, propulsive mechanism 4 is also connected with testing agency 6, passes through the detection machine in progradation Structure 6 judges the propulsive mechanism 4 to the advance distance of the load carrier 5.
Referring to fig. 2, Fig. 3, Fig. 4 and Fig. 5, it is described in one embodiment of the board-washing device of optional ELISA Plate hole location cleaning Board-washing mechanism 2 includes Z-direction elevator 7, and 7 top of Z-direction elevator is connected with hanging plate 8, and 8 side of hanging plate is connected with board-washing First 9, board-washing needle 10,5 top of load carrier of the arrangement of board-washing needle 10 in the process of running are connected with below board-washing head 9.Z-direction The hanging plate 8 on 7 top of elevator is used to connect board-washing head 9, while the lifting of hanging plate 8 is driven by the movement of Z-direction elevator 7, into And realize the lifting of board-washing head 9 and board-washing needle 10, board-washing needle 10 include jet cleaning liquid and draw cleaning after waste liquid two column needles, Board-washing needle 10 itself belongs to the prior art.7 middle part of Z-direction elevator extends to form driving portion 11, the driving portion to side 11 lower sections are connected with Z-direction driving motor 12, and 12 side of Z-direction driving motor is connected with Z-direction motor fixing seat 13, in Z-direction elevator 7 Side is connected with Z-direction riser guide 14, and Z-direction riser guide 14 is connect with 13 side of Z-direction motor fixing seat.Z-direction driving motor 12 realize that the lifting of driving portion 11, the lifting of driving portion 11 make Z-direction elevator 7 along Z-direction riser guide 14 by motor polished rod 15 It moves up and down, and then guarantees the accuracy of Z-direction elevator 7.
Referring to fig. 2, Fig. 3, Fig. 4 and Fig. 5, it is described in one embodiment of the board-washing device of optional ELISA Plate hole location cleaning Load carrier 5 includes ELISA Plate seat 16, and 16 upper end of ELISA Plate seat is formed with ELISA Plate slot 17, is connected with and puts on the inside of ELISA Plate seat 16 Slot 18 is set, 18 outside of slot is shelved and is connect with the propulsive mechanism 4.ELISA Plate seat 16 places enzyme to be cleaned by ELISA Plate slot 17 Target substrate can be cleaned any position culture dish holding on ELISA Plate substrate by board-washing mechanism 2, and board-washing device uses After, the board-washing needle 10 of board-washing mechanism 2 can be resetted in shelving in slot 18, facilitate next use, while preventing board-washing needle 10 Pollution.
Referring to fig. 2, Fig. 3, Fig. 4 and Fig. 5, it is described in one embodiment of the board-washing device of optional ELISA Plate hole location cleaning Propulsive mechanism 4 includes slide bar 19, and the slide bar 19 connects on the outside of slot 18 with described shelve, under slide bar 19 and the ELISA Plate seat 16 Portion is equipped with slideway 20, and the slide bar 19 drives the ELISA Plate seat 16 to move back and forth along the slideway 20, and the outside of slideway 20 connects It is connected to press button mechanism 21.Slide bar 19 is connect by hinged shaft 22 with shelving on the outside of slot 18, and slide bar 19 is able to drive 16 edge of ELISA Plate seat Slideway 20 moves, so that ELISA Plate to be cleaned be made to pass through from the lower section of board-washing mechanism, the press button mechanism 21 in 20 outside of slideway can To select the cleaning hole location of ELISA Plate, board-washing mechanism is made only to clean specific hole location.Specific principle is that testing agency 6 is equipped with Detection lug 23, detection lug 23 pass through optoelectronic switch 36, and 23 lower end of detection lug is formed with stroke detection block 24, stroke detection block 24 Center spacing is identical as the spacing of two column culture dish adjacent on ELISA Plate to be detected.So as to accurate really according to detection lug 23 Surely the hole location cleaned controls the start and stop of board-washing mechanism 2 by control mechanism 1 using existing automated control technology.
Referring to fig. 2, Fig. 3, Fig. 4 and Fig. 5, it is described in one embodiment of the board-washing device of optional ELISA Plate hole location cleaning Propulsive mechanism 4 further includes Y-direction movement sliding rail 25, and 19 end of slide bar is downwardly extending Y-direction drive block 26, and the Y-direction is driven 26 side of motion block is connected with Y-direction movement sliding rail 25, and 26 lower end of Y-direction drive block is connected with Y-direction timing belt 27, the Y-direction timing belt 27 are connected with Y-direction driving motor 28;19 end of slide bar extends across the Y-direction movement sliding rail 25 outward and forms detection Docking section 29.Y-direction driving motor 28 drives Y-direction drive block 26 to move by Y-direction timing belt 27, so that slide bar 19 is moved, by It is connected in the detection docking section 29 of testing agency 6 and propulsive mechanism 4, can be realized the fortune synchronous with propulsive mechanism 4 of testing agency 6 It is dynamic.
Referring to fig. 2, Fig. 3, Fig. 4 and Fig. 5, it is described in one embodiment of the board-washing device of optional ELISA Plate hole location cleaning The top of slide bar 19 is equipped with middle vertical plate 30, and middle 30 lower end of vertical plate is formed with bar channel 31, slide bar 19 pass through the bar channel 31 with Described shelve connects on the outside of slot 18, and middle 30 upper end of vertical plate is connected with indication mechanism 32.Indication mechanism 32 is for board-washing content and sets Interface display is set, chip is equipped with by control panel setting and adjustment parameter, inside, setting instruction is executed by chip, drives Z Lifting, the on-off of board-washing needle 10 and the moving forward and backward for ELISA Plate seat 16 of board-washing head 9 are controlled to driving motor 12.Indication mechanism 32 Control with control panel belongs to the prior art.
Referring to fig. 2, Fig. 3, Fig. 4 and Fig. 5, it is described in one embodiment of the board-washing device of optional ELISA Plate hole location cleaning Testing agency 6 includes detection lug 23, and detection lug 23 passes through the optoelectronic switch 36 for being connected to the propulsive mechanism 4, the detection lug 23 lower ends are formed with stroke detection block 24, adjacent two column in the center spacing of the stroke detection block 24 and ELISA Plate to be detected The spacing of culture dish is identical.Stroke detection block 24 is designed as zigzag, and the center spacing of stroke detection block 24 with it is to be detected ELISA Plate on adjacent two column culture dish spacing it is identical, to block realization to optoelectronic switch 36 by stroke detection block 24 The tally control of stroke signal, and then determine the moving distance of propulsive mechanism 4.
Referring to fig. 2, Fig. 3, Fig. 4 and Fig. 5, it is described in one embodiment of the board-washing device of optional ELISA Plate hole location cleaning Fluid path mechanism 3 includes cleaning solution route 33 and waste liquid circuit 34, is connected separately with electricity on cleaning solution route 33 and waste liquid circuit 34 Magnet valve, vacuum pump, cleaning solution route 33 are connected with external cleaning solution bucket, and waste liquid circuit 34 is connected with external waste liquid barrel.Clearly The connection of washing lotion route 33, waste liquid circuit 34 and solenoid valve, vacuum pump belongs to the prior art, passes through cleaning solution route 33 and waste liquid The on-off of 9 fluid path of board-washing head is realized in circuit 34, and the start and stop of solenoid valve, vacuum pump are determined according to hole location and detection lug 23 to be cleaned Distance controlled, specific automation control belongs to the prior art.
Referring to fig. 2, Fig. 3, Fig. 4 and Fig. 5, it is described in one embodiment of the board-washing device of optional ELISA Plate hole location cleaning The lower section of load carrier 5 is equipped with receiving channel 35, and the testing agency 6 is under the drive of the propulsive mechanism 4 in and out of described In receiving channel 35.Receiving channel 35 the position for promoting load carrier 5 simultaneously, keep testing agency 6 logical in and out of accommodating In road 35.
When board-washing of the present invention, ELISA Plate seat 16 is placed into ELISA Plate substrate to be cleaned by ELISA Plate slot 17, in enzyme mark Any position culture dish holding is cleaned by board-washing mechanism 2 on plate substrate, realizes the structure of optional hole location cleaning of the invention It is characterized by 23 lower end of detection lug and is formed with stroke detection block 24, the center spacing of stroke detection block 24 and ELISA Plate to be detected The spacing of upper adjacent two column culture dish is identical, judges propulsive mechanism 4 to load carrier 5 by testing agency 6 in progradation Advance distance, control mechanism 1 are laid out the propulsion stroke and board-washing for determining propulsive mechanism 4 according to culture dish to be cleaned on ELISA Plate The board-washing position of mechanism 2, propulsive mechanism 4 make load carrier 5 according to propulsion stroke motion in board-washing according to determining propulsion stroke The lower section of mechanism 2.
It is placed in putting in order on ELISA Plate according to culture dish sample, the hole location on corresponding indication mechanism 32 passes through control Panel processed sets the hole location for wanting board-washing, and chip executes instruction, and controls the on-off of corresponding position board-washing needle 10, washes if necessary Plate, corresponding 10 fluid path of board-washing needle is just connected to, if you do not need to board-washing, corresponding 10 fluid path of board-washing needle is shut off, and chip can lead to The on-off quantity of board-washing needle 10 is crossed to adjust the pressure and flow of board-washing fluid path, reaches flow matches;Board-washing head 9 moves up and down, Board-washing movement is carried out, ELISA Plate pallet moves forward and backward, and carries out movement of changing gear.After board-washing device use, board-washing mechanism 2 is washed Plate needle 10 is resetted in shelving in slot 18, facilitates next use, while preventing board-washing needle 10 from polluting.
During board-washing, Z-direction driving motor 12 realizes the lifting of driving portion 11, the liter of driving portion 11 by motor polished rod 15 Drop moves up and down Z-direction elevator 7 along Z-direction riser guide 14, and the movement of Z-direction elevator 7 drives the lifting of hanging plate 8, Jin Ershi The lifting of existing board-washing head 9 and board-washing needle 10.Y-direction driving motor 28 drives Y-direction drive block 26 to move by Y-direction timing belt 27, from And slide bar 19 is moved, since testing agency 6 and propulsive mechanism 4 connect, it can be realized the same of testing agency 6 and propulsive mechanism 4 Step movement.Stroke detection block 24 is designed as zigzag, and on the center spacing of stroke detection block 24 and ELISA Plate to be detected The spacing of adjacent two column culture dish is identical, to realize stroke signal to blocking for optoelectronic switch 36 by stroke detection block 24 Tally control, and then determine the moving distance of propulsive mechanism 4.Selection cleaning can be carried out to any hole location through the invention, it can It is configured on the control panel according to the hole location that cleaning is actually needed in test experience, board-washing head 9 is realized by electrical control On board-washing needle 10 logical liquid only is carried out to the corresponding hole site of setting, the hole location not set carries out disconnected liquid, realizes that specific hole location is clear It washes, present invention omits the step of typesetting perforations adding, shorten the test experience time before upper machine, reduce labor intensity, reduce The risk of corrupt data has prevented unnecessary waste, has saved testing cost.
Each technical characteristic of embodiment described above can be combined arbitrarily, for simplicity of description, not to above-mentioned reality It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited In contradiction, all should be considered as described in this specification.
The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to protection of the invention Range.Therefore, the scope of protection of the patent of the invention shall be subject to the appended claims.

Claims (10)

1. a kind of board-washing device of optional ELISA Plate hole location cleaning, the board-washing device are used to clean the culture dish of ELISA Plate, wash Panel assembly includes control mechanism (1) and board-washing mechanism (2), the fluid path mechanism (3) connecting with the board-washing mechanism (2), feature Be: the board-washing device further includes propulsive mechanism (4), the load carrier (5) connecting with the propulsive mechanism (4), the control Mechanism (1) processed determines the propulsion stroke of the propulsive mechanism (4) according to culture dish layout to be cleaned on ELISA Plate and described washes The board-washing position of trigger structure (2), propulsive mechanism (4) make the load carrier (5) go according to propulsion according to determining propulsion stroke Cheng Yundong is also connected with testing agency (6) in the lower section of the board-washing mechanism (2), propulsive mechanism (4), passes through institute in progradation Stating testing agency (6) judges the propulsive mechanism (4) to the advance distance of the load carrier (5).
2. a kind of board-washing device of optional ELISA Plate hole location cleaning according to claim 1, it is characterised in that: the board-washing Mechanism (2) includes Z-direction elevator (7), and Z-direction elevator (7) top is connected with hanging plate (8), hanging plate (8) the side connection Have board-washing head (9), is connected with board-washing needle (10) below board-washing head (9), board-washing needle (10) arrangement holding in the process of running Above mounted mechanism (5).
3. a kind of board-washing device of optional ELISA Plate hole location cleaning according to claim 2, it is characterised in that: the Z-direction It is extended to form driving portion (11) in the middle part of elevator (7) to side, is connected with Z-direction driving motor below the driving portion (11) (12), Z-direction driving motor (12) side is connected with Z-direction motor fixing seat (13), and Z-direction lifting is connected on the inside of Z-direction elevator (7) Guide rail (14), Z-direction riser guide (14) are connect with Z-direction motor fixing seat (13) side.
4. a kind of board-washing device of optional ELISA Plate hole location cleaning according to claim 1, it is characterised in that: the carrying Mechanism (5) includes ELISA Plate seat (16), and ELISA Plate seat (16) upper end is formed with ELISA Plate slot (17), is connected on the inside of ELISA Plate seat (16) It is connected to and shelves slot (18), shelve and connect on the outside of slot (18) with the propulsive mechanism (4).
5. a kind of board-washing device of optional ELISA Plate hole location cleaning according to claim 4, it is characterised in that: the propulsion Mechanism (4) includes slide bar (19), and the slide bar (19) connect on the outside of slot (18) with described shelve, slide bar (19) and the ELISA Plate Seat (16) lower part is equipped with slideway (20), and the slide bar (19) drives the ELISA Plate seat (16) back and forth to transport along the slideway (20) It is dynamic, press button mechanism (21) are connected on the outside of slideway (20).
6. a kind of board-washing device of optional ELISA Plate hole location cleaning according to claim 5, it is characterised in that: the propulsion Mechanism (4) further includes Y-direction movement sliding rail (25), and slide bar (19) end is downwardly extending Y-direction drive block (26), the Y It is connected with Y-direction to drive block (26) side to move sliding rail (25), Y-direction drive block (26) lower end is connected with Y-direction timing belt (27), institute It states Y-direction timing belt (27) and is connected with Y-direction driving motor (28);Slide bar (19) end extends across the Y-direction outward It moves sliding rail (25) and forms detection docking section (29).
7. a kind of board-washing device of optional ELISA Plate hole location cleaning according to claim 5, it is characterised in that: the slide bar (19) top is equipped with middle vertical plate (30), and middle vertical plate (30) lower end is formed with bar channel (31), and slide bar (19) is logical across the bar Road (31) is connect on the outside of slot (18) with described shelve, and middle vertical plate (30) upper end is connected with indication mechanism (32).
8. a kind of board-washing device of optional ELISA Plate hole location cleaning according to claim 1, it is characterised in that: the detection Mechanism (6) includes detection lug (23), and detection lug (23) passes through the optoelectronic switch (36) for being connected to the propulsive mechanism (4), described Detection lug (23) lower end is formed with stroke detection block (24), the center spacing of the stroke detection block (24) and enzyme mark to be detected The spacing of adjacent two column culture dish is identical on plate.
9. a kind of board-washing device of optional ELISA Plate hole location cleaning according to claim 1, it is characterised in that: the fluid path Mechanism (3) includes cleaning solution route (33) and waste liquid circuit (34), is connected respectively on cleaning solution route (33) and waste liquid circuit (34) It is connected to solenoid valve, vacuum pump, cleaning solution route (33) is connected with external cleaning solution bucket, and waste liquid circuit (34) are connected with external Waste liquid barrel.
10. a kind of board-washing device of optional ELISA Plate hole location cleaning according to claim 1, it is characterised in that: described to hold The lower section of mounted mechanism (5) is equipped with receiving channel (35), and the testing agency (6) enters and leaves under the drive of the propulsive mechanism (4) In the receiving channel (35).
CN201810929881.3A 2018-08-15 2018-08-15 A kind of board-washing device of optional ELISA Plate hole location cleaning Pending CN109107954A (en)

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Application Number Priority Date Filing Date Title
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110814658A (en) * 2019-11-15 2020-02-21 深圳市佳鑫一帆科技有限公司 Manufacturing method of high-precision plate washing head
CN114178226A (en) * 2021-11-05 2022-03-15 山东博科生物产业有限公司 Plate washing machine integrating drying plate sterilization function

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WO2013044454A1 (en) * 2011-09-27 2013-04-04 深圳市亚辉龙生物科技有限公司 Full-automatic immunity analyzer and detection method thereof
CN103230902A (en) * 2013-03-26 2013-08-07 山东博科生物产业有限公司 Enzyme-labeling washing plate mechanism
CN208840079U (en) * 2018-08-15 2019-05-10 烟台艾德康生物科技有限公司 A kind of board-washing device of optional ELISA Plate hole location cleaning

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2816812Y (en) * 2005-09-07 2006-09-13 张传国 Efficient enzyme mark plate-washing machine
DE102006061222A1 (en) * 2006-12-20 2008-07-03 Tecan Trading Ag Microplate washing device, has wash head fixed in operating position, and plate carrier rotatable around vertical axis and adjustably formed in direction that stays perpendicular to support of microplate on plate carrier
CN201016983Y (en) * 2007-03-05 2008-02-06 深圳市汇松科技发展有限公司 Improved type enzyme-labeled plate washer
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CN208840079U (en) * 2018-08-15 2019-05-10 烟台艾德康生物科技有限公司 A kind of board-washing device of optional ELISA Plate hole location cleaning

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110814658A (en) * 2019-11-15 2020-02-21 深圳市佳鑫一帆科技有限公司 Manufacturing method of high-precision plate washing head
CN114178226A (en) * 2021-11-05 2022-03-15 山东博科生物产业有限公司 Plate washing machine integrating drying plate sterilization function

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Inventor after: Zhang Lihai

Inventor after: Gao Hairong

Inventor after: Dong Liying

Inventor after: Shao Wei

Inventor after: Zhang Meng

Inventor after: Wang Xiaofeng

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