CN109030096A - Take liquid test method and device - Google Patents

Take liquid test method and device Download PDF

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Publication number
CN109030096A
CN109030096A CN201810574198.2A CN201810574198A CN109030096A CN 109030096 A CN109030096 A CN 109030096A CN 201810574198 A CN201810574198 A CN 201810574198A CN 109030096 A CN109030096 A CN 109030096A
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China
Prior art keywords
liquid
probe
take
test
taking
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CN201810574198.2A
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Chinese (zh)
Inventor
丁伟
王卫佳
程威睿
刘强
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Maccura Medical Electronics Co Ltd
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Maccura Medical Electronics Co Ltd
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Priority to CN201810574198.2A priority Critical patent/CN109030096A/en
Publication of CN109030096A publication Critical patent/CN109030096A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/10Devices for withdrawing samples in the liquid or fluent state
    • G01N1/14Suction devices, e.g. pumps; Ejector devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1011Control of the position or alignment of the transfer device

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  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Hydrology & Water Resources (AREA)
  • Measurement Of Levels Of Liquids Or Fluent Solid Materials (AREA)

Abstract

This application provides one kind to take liquid test method and device, is related to bio-medical technology field.Take liquid test method, comprising: in the case where defaulting probe and taking the successful situation of liquid during once taking liquid, control the probe to the release of no liquid container it is described once take liquid during the liquid got;It controls the probe and carries out liquid level test in the no liquid container;If the probe is touching liquid level within the scope of no liquid container bottom preset height, verify the probe it is described once take liquid during take liquid success, preset height range obtained based on the expectation liquid-taken amount of probe.It can reduce judgement using the technical solution of the application and take the whether successful False Rate of liquid.

Description

Take liquid test method and device
Technical field
The present invention relates to biologic medical fields more particularly to one kind to take liquid test method and device.
Background technique
In biologic medical field, it is often necessary to carry out all kinds of experiments.During being tested, need to contain from liquid It puts and draws liquid in container.Specifically, for drawing the probe of liquid driven by the motor in liquid in liquid absorbing device Downlink or uplink in container.Probe encounters the bottom of liquid containing container in order to prevent, and prevents from being drawn to and not need Liquid, when probe touches the liquid level of liquid containing liquid in containers, probe draw liquid.It, will after probe draws liquid Liquid is transferred in other containers and releases.
Draw liquid practical operation in often exist such as bubble, electrostatic, electromagnetic interference, distribution capacity factor shadow It rings, is mistaken for having touched liquid level when causing probe also not in contact with liquid level, take liquid to be unsuccessfully mistaken for taking liquid success, cause to take The successful False Rate of liquid is higher.At this stage, the successful False Rate of liquid is taken in order to reduce, liquid absorbing device will record to be visited each time Needle touches the position of liquid level.The position of liquid level is touched by comparing the position of current probe and the last probe of record, Judge whether current probe touches liquid level.If two position difference distances exceed reasonable threshold value, it is determined that current probe is not Liquid level is touched, takes liquid also and failed, judges by accident.But for only needing single to take the scene of liquid and for the first time taking liquid For scene, and the case where last probe touches the liquid level is not present, therefore can not judge whether current probe takes liquid Success, False Rate are still higher.
Summary of the invention
The embodiment of the invention provides one kind to take liquid test method and device, can reduce judgement and takes whether liquid successfully misses Sentence rate.
In a first aspect, the present invention provides one kind to take liquid test method, comprising: in default probe during once taking liquid It takes in the successful situation of liquid, control probe discharges the liquid got during once taking liquid to no liquid container;Control probe Liquid level test is carried out in no liquid container;If probe is touching liquid level within the scope of no liquid container bottom preset height, Verifying probe takes liquid success during once taking liquid, and preset height range is obtained based on the expectation liquid-taken amount of probe.
Second aspect, the present invention provides one kind to take liquid test device, including takes liquid test circuit and probe;Probe is used for Take liquid;It takes liquid test circuit to be used in the case where defaulting probe and taking the successful situation of liquid during once taking liquid, controls probe to nothing Liquid container discharges the liquid got during once taking liquid;And liquid is carried out in no liquid container for controlling probe Face test;And if touching liquid level within the scope of no liquid container bottom preset height for probe, probe is verified one Secondary that liquid is taken to take liquid success in the process, preset height range is obtained based on the expectation liquid-taken amount of probe.
The present invention provides one kind to take liquid test method and device, and liquid success is taken during once taking liquid defaulting probe In the case where, control probe discharges liquid into no liquid container.Control probe carries out detecting liquid level in no liquid container.If Probe touches liquid level within the scope of no liquid container bottom preset height during carrying out detecting liquid level, shows no liquid There is the liquid for meeting expectation liquid-taken amount in container.Prove that probe has got enough liquid during once taking liquid, also It is to say, verifying probe takes liquid success during once taking liquid, and there is no judge by accident.To more accurately sentence by verifying Determine probe and takes whether liquid succeeds during once taking liquid.It improves and determines to take the whether successful accuracy of liquid, reduce judgement and take The whether successful False Rate of liquid.
Detailed description of the invention
The present invention may be better understood from the description with reference to the accompanying drawing to a specific embodiment of the invention wherein, The same or similar appended drawing reference indicates the same or similar feature.
Fig. 1 is a kind of application scenarios schematic diagram in the embodiment of the present invention;
Fig. 2 is a kind of in the embodiment of the present invention frequency of oscillation of probe signals and the relation curve of time during liquid to be taken to show It is intended to;
Fig. 3 is a kind of in the embodiment of the present invention to take the variable quantity of the frequency of oscillation of probe signals and the pass of time during liquid It is curve synoptic diagram;
Fig. 4 is a kind of flow chart for taking liquid test method in the embodiment of the present invention;
Fig. 5 is a kind of structural schematic diagram for taking liquid test device in the embodiment of the present invention;
Fig. 6 is the hardware structural diagram that one of embodiment of the present invention takes liquid equipment.
Specific embodiment
The feature and exemplary embodiment of various aspects of the invention is described more fully below.In following detailed description In, many details are proposed, in order to provide complete understanding of the present invention.But to those skilled in the art It will be apparent that the present invention can be implemented in the case where not needing some details in these details.Below to implementation The description of example is used for the purpose of providing by showing example of the invention and better understanding of the invention.The present invention never limits In any concrete configuration set forth below and algorithm, but cover under the premise of without departing from the spirit of the present invention element, Any modification, replacement and the improvement of component and algorithm.In the the accompanying drawings and the following description, well known structure and skill is not shown Art is unnecessary fuzzy to avoid causing the present invention.
It is referred in the application described in the expression such as " one embodiment ", " embodiment ", " each embodiment ", " example " (one or more) embodiment or example may include specific feature, structure or feature, but not be each embodiment or example It must include specific feature, structure or the feature.Moreover, the phrase " in one example " reused is not necessarily referring to together One example, although it may refer to same example.
It is provided in an embodiment of the present invention to take liquid test method, device, liquid equipment and storage medium is taken to can be applied to biology, doctor In the scene in the fields such as, chemistry, physics needing that liquid is taken to be tested or tested.Fig. 1 is that one kind is answered in the embodiment of the present invention Use schematic diagram of a scenario.As shown in Figure 1, the probe of liquid test device is taken to move up and down under the control for taking liquid test circuit, and inhale Take the liquid (taking liquid) held in liquid container.During once taking liquid, probe is gradually reduced above liquid, until visiting A part of needle submerges liquid, and probe stop motion carries out taking liquid.When reaching the scheduled liquid for taking liquid duration or acquirement Amount reaches predetermined amount, then probe terminates to take liquid, and is gradually increasing, until being reset to position when liquid process being taken to start where probe It sets.
During taking liquid, take liquid test device can be according to the variation of probe signals, to judge whether probe touches liquid Face.During probe is not in contact with to liquid level, probe always in a certain medium (can be air) in embodiments of the present invention Movement, probe signals are unchanged or variation is smaller.Before leaving liquid level to probe after probe contacts liquid level, the head one of probe Directly stop in a certain medium (in embodiments of the present invention can be liquid) or movement, probe signals are unchanged or variation compared with It is small.
Never touch liquid level to during touching liquid level in probe, due to probe head from a certain medium ( Can be air in the embodiment of the present invention) enter another transfer (in embodiments of the present invention can be liquid), probe signals can be unexpected Large change (mutating) occurs, generates larger fluctuation.But due to the influence of extraneous factor, for example, bubble, electrostatic, Electromagnetic interference, distribution capacity etc. can also cause probe signals and large change (mutating) occur suddenly, generate larger wave It is dynamic.Under the influence of extraneous factor, probe can also may also be mistaken for probe contact liquid level not in contact with to liquid level.Erroneous judgement occurs Afterwards, probe starts to take liquid not in contact with liquid level, leads to that liquid is taken to fail.Alternatively, since probe enters the distance of liquid level It is mismatched with scheduled liquid-taken amount, so that causing to take liquid insufficient taking liquid process middle probe to be detached from liquid level.Taking liquid deficiency is to take liquid A kind of embodiment of failure.
In one example, probe signals, which mutate, can be embodied in the frequency of oscillation mutation of probe signals. For example, Fig. 2 is a kind of in the embodiment of the present invention frequency of oscillation of probe signals and the relation curve of time during liquid to be taken to illustrate Figure.As shown in Fig. 2, by taking noise is extraneous factor as an example.Noise will lead to frequency of oscillation mutation.Probe enters liquid from air Body and probe enter air from liquid and will lead to frequency of oscillation mutation.Therefore, noise and liquid process middle probe is taken to take Liquid is successfully difficult to differentiate between.
Fig. 3 is a kind of in the embodiment of the present invention to take the variable quantity of the frequency of oscillation of probe signals and the pass of time during liquid It is curve synoptic diagram.As shown in figure 3, during taking liquid successfully once to take liquid, when probe contacts liquid level, the vibration of probe signals The variable quantity for swinging frequency mutates.Probe enters liquid level and carries out during taking liquid, the change of the frequency of oscillation of probe signals Change amount is gradually reduced, until zero.When probe leaves liquid level, the variable quantity of the frequency of oscillation of probe signals occurs prominent again Become.During probe leaves liquid level rising reset, the variable quantity of the frequency of oscillation of probe signals is gradually reduced, until zero.
Probe will do it during taking liquid takes whether liquid successfully determines, but can be obtained by above description, might have outer Boundary's factor has an impact the signal of the probe of acquisition, so as to cause liquid will be taken unsuccessfully to be mistaken for taking liquid success.Of the invention real Apply in example, by probe once take liquid during determine take liquid be successfully known as " default probe once take liquid during take liquid at Function ".It is provided in an embodiment of the present invention to take liquid test side in the case where defaulting probe and taking the successful situation of liquid during once taking liquid Method, device, equipment and storage medium can take liquid successfully to determine to verify to probe during this time taking liquid, thus Determine that default probe takes liquid success whether correct during once taking liquid.And then it improves and determines to take liquid whether successfully accurate Property, it reduces and determines to take the whether successful False Rate of liquid.
Fig. 4 is a kind of flow chart for taking liquid test method in the embodiment of the present invention.As shown in figure 4, taking liquid test method packet Step S101 is included to step S104.
In step s101, in the case where defaulting probe and taking the successful situation of liquid during once taking liquid, probe is controlled to nothing Liquid container discharges the liquid got during once taking liquid.
In the case where defaulting probe and taking the successful situation of liquid during once taking liquid, the liquid that takes liquid test device that can will get Release, with pending experiment.In embodiments of the present invention, it can use a no liquid container, control probe discharges the liquid got Into no liquid container.It should be noted that before probe does not discharge the liquid got also, no liquid in the no liquid container In the presence of.For example, no liquid container can be empty container before probe does not discharge the liquid got also.For example, no liquid container For an empty beaker or an empty test tube.
In the case where once liquid process being taken to terminate and default and take the successful situation of liquid, controls probe and vacantly released into no liquid container Tapping body.After guaranteeing that probe releases the liquid got, probe is not contacted with the liquid in no liquid container.
If probe takes liquid success during this time taking liquid really, probe has been drawn to liquid.In probe to aneroid After the liquid that the release of body container is got, the liquid of probe release got is contained in no liquid container.
If probe will take liquid to be unsuccessfully mistaken for taking liquid success during this time taking liquid, probe is not drawn to liquid. After the liquid that probe is got to the release of no liquid container, still without liquid in no liquid container.
Alternatively, probe may be drawn if probe will take liquid to be unsuccessfully mistaken for taking liquid success during this time taking liquid Liquid has been arrived, but has not been drawn to the liquid for meeting expectation liquid-taken amount.After the liquid that probe is got to the release of no liquid container, nothing The amount of liquid in liquid container can not reach desired liquid-taken amount.
In step s 102, control probe carries out liquid level test in no liquid container.
Control probe carries out liquid level test in no liquid container, is equivalent to and takes liquid to take whether liquid succeeds in the process to primary Verifying.Specifically, taking the control probe decline of liquid test device after the liquid that probe is got to the release of no liquid container.For Guarantee the accuracy of liquid level test, controllable manufacturing probe slowly declines.During probe decline, it can repeatedly obtain probe and exist Measurement parameter in no liquid container.And measurement of comparison variable quantity and test judgement threshold value.
Wherein, measurement variable quantity is the variable quantity of the measurement parameter currently obtained and the last measurement parameter obtained.It needs It is noted that in the present embodiment, measurement variable quantity is positive value.For example, the survey that measurement variable quantity concretely currently obtains Measure the absolute value of the difference of parameter and the last measurement parameter obtained.Test judgement threshold value is to limit whether probe touches liquid level Boundary value, can be preset.Specifically, test judgement threshold value can be set according to operative scenario or work requirements, herein not Limitation.
In one example, the period of measurement parameter of the settable acquisition probe in no liquid container, such as setting obtain The period for taking measurement parameter is 10 milliseconds, then during taking liquid, every 10 milliseconds, takes liquid test device to obtain a probe and exist Measurement parameter in no liquid container.
Above-mentioned measurement parameter is the parameter for causing probe signals to change.For example, capacitor, resistance, inductance, pressure, probe are believed Number frequency of oscillation in it is one or more.During probe enters liquid from air, the capacitor of probe, resistance, inductance, Pressure can mutate, and the capacitor of probe, resistance, inductance, pressure mutates can be embodied as the oscillation of probe signals Frequency mutates.For the ease of hourly observation and judgement, the frequency of oscillation of probe signals can be monitored and be obtained.Than Such as, can variation according to RC oscillator principle by probe relative to the value of the capacitor on ground, be converted into and be easier to monitored probe The frequency of oscillation of signal or charge and discharge time in the cycle of oscillation of probe signals, capacitor are inversely proportional with frequency of oscillation.For another example, Can variation according to LC oscillator principle by probe relative to the value of the capacitor on ground, be converted into and be easier to monitored probe signals Frequency of oscillation or probe signals cycle of oscillation in the charge and discharge time.
In step s 103, if probe is touching liquid level, verifying spy within the scope of no liquid container bottom preset height Needle takes liquid success during once taking liquid.
Wherein, no liquid container bottom is the bottom end of no liquid container.Preset height range takes liquid based on the expectation of probe It measures.The liquid containing of desired liquid-taken amount can be calculated in nothing according to the area of desired liquid-taken amount and no liquid container bottom Accessible height in liquid container.Preset height range includes it is expected that the liquid containing of liquid-taken amount is reachable in no liquid container The height arrived.
In one example, can using the liquid containing of desired liquid-taken amount in no liquid container accessible height as pre- If the central value of altitude range, certain departure can be taken respectively in central value augment direction and reduction direction, to be formed pre- If altitude range.For example, central value is set as 1 centimetre, then it is each to the direction greater than 1 centimetre and the difference of the direction less than 1 centimetre From the departure for going 0.2 centimetre, obtaining preset height range is 0.8 centimetre to 1.2 centimetres.
In another example, can using the liquid containing of desired liquid-taken amount in no liquid container accessible height as The maximum value of preset height range, to form preset height range.For example, the liquid containing of expectation liquid-taken amount holds in no liquid Accessible height is 1 centimetre in device, then preset height range is 0 to 1 centimetre.
Probe is touching liquid level within the scope of no liquid container bottom preset height, then it represents that probe is once taking liquid mistake Really liquid success is taken in journey.And probe discharges the liquid got into no liquid container, meets so that existing in no liquid container Take the liquid of liquid success conditions.Therefore, it may be verified that probe takes liquid success really during once taking liquid, during once taking liquid Whether judgement takes liquid to succeed, and there is no judge by accident.
In one example, if liquid level test is realized by measurement of comparison variable quantity and test judgement threshold value.If then probe When within the scope of no liquid container bottom preset height, measurement variable quantity is greater than test judgement threshold value, it may be verified that probe is one It is secondary that liquid is taken to take liquid success really in the process.
For example, if preset height range is 0.8 centimetre to 1.2 centimetres.Probe apart from 0.8 centimetre of no liquid container bottom extremely Measurement variable quantity in the range of 1.2 centimetres is 0.2MHz (megahertz), and test judgement threshold value is 0.019MHz.Due to 0.2MHz > 0.19MHz, therefore verify probe and take liquid success really during once taking liquid.
During probe contacts liquid level not in contact with liquid level to probe, the signal of probe can mutate.Specifically, table Now mutate for the variable quantity of measurement parameter.Here " mutation " refers to that whithin a period of time measurement parameter increases or drop Low amount is more than threshold value.Therefore, if measurement variable quantity is greater than test judgement threshold value, under can determine probe in no liquid container In capable process, probe completes the movement for entering liquid from air, thus verify probe once take liquid during take liquid at Function.
In step S104, if probe, not in contact with liquid level is arrived, is verified within the scope of no liquid container bottom preset height Probe takes liquid to fail during once taking liquid.
Probe within the scope of no liquid container bottom preset height not in contact with arriving liquid level, then it represents that probe is once taking liquid Liquid is taken to fail in the process, probe does not get liquid or probe takes liquid insufficient.Probe can not be released into no liquid container Liquid, no liquid container still maintain the state of no liquid.Alternatively, probe can not be released into no liquid container it is enough Liquid, the height of the liquid in no liquid container is outside preset height range.It therefore, can be by probe apart from no liquid container Not in contact with liquid level is arrived within the scope of the preset height of bottom, verifying probe takes liquid to fail during once taking liquid.During once taking liquid Judgement takes whether liquid is successfully judged by accident.
In one example, if liquid level test is realized by measurement of comparison variable quantity and test judgement threshold value.If in distance Measurement of comparison variable quantity and test judgement threshold value when within the scope of no liquid container bottom preset height, measurement variable quantity are less than or equal to Test judgement threshold value, it may be verified that probe takes liquid to fail during once taking liquid.
For example, if preset height range is 0.8 centimetre to 1.2 centimetres.Probe apart from 0.8 centimetre of no liquid container bottom extremely Measurement variable quantity in the range of 1.2 centimetres is 0.02MHz (megahertz), and test judgement threshold value is 0.019MHz.Due to 0.02MHz < 0.19MHz, therefore verify probe and take liquid to fail during once taking liquid, that is to say, that once taking liquid process It is successfully erroneous judgement that middle judgement, which takes liquid,.
In embodiments of the present invention, after taking liquid process, the liquid got during liquid will be taken to discharge to no liquid In container, liquid level test is carried out according to the no liquid container for discharging liquid to probe, takes whether liquid takes liquid in the process to verify Success.It, can be to taking liquid to take whether liquid successfully carries out more accurate judgement in the process, so that improving judgement takes liquid by verifying Whether successful accuracy, reduce judgement and take the whether successful False Rate of liquid.Moreover, in embodiments of the present invention, and be not required to Additionally to increase new device in taking liquid test device.That is, guaranteeing not increasing to take liquid test device complexity On the basis of, it can be improved judgement and take the whether successful accuracy of liquid, reduce judgement and take the whether successful False Rate of liquid.
Fig. 5 is a kind of structural schematic diagram for taking liquid test device in the embodiment of the present invention.As shown in figure 5, taking liquid test dress It sets including probe 21 and liquid is taken to test circuit 22.
Wherein, probe 21 is for taking liquid.
It takes liquid test circuit 22 to be used in the case where defaulting probe and taking the successful situation of liquid during once taking liquid, controls probe The liquid got during once taking liquid is discharged to no liquid container 34.Liquid test circuit 22 is taken to be also used to control probe in nothing Liquid level test is carried out in liquid container 34.If liquid test circuit 22 is taken to be also used to probe apart from no liquid container bottom preset height Liquid level is touched in range, verifying probe takes liquid success during once taking liquid.Wherein, preset height range is based on probe It is expected that liquid-taken amount obtains.
In one example, taking liquid test circuit 22 includes detecting module 221.Detecting module 221 is visited for repeatedly obtaining Measurement parameter of the needle in no liquid container 34, measurement parameter are the parameter for causing probe signals to change.Detecting module 221 is also used In measurement of comparison variable quantity and test judgement threshold value, measuring variable quantity is the measurement parameter currently obtained and the last survey obtained Measure the variable quantity of parameter.
Specifically, if detecting module 221 can be specifically used for probe when within the scope of no liquid container bottom preset height It measures variable quantity and is greater than test judgement threshold value, then verify probe and take liquid success during once taking liquid
In one example, if detecting module 221 can also be used in probe apart from no liquid container bottom preset height range It is interior not in contact with arrive liquid level, verifying probe once take liquid during take liquid to fail.
In one example, above-mentioned measurement parameter may include the frequency of oscillation of capacitor, resistance, inductance, pressure, probe signals In it is one or more, do not limit herein.
It should be noted that liquid test circuit is taken to may also include signal processing module 222, conversion module 223, conditioning module 224 and control module 225.
Wherein, settable external power supply 23 is that liquid test device is taken to power.Conditioning module 224 can be by probe relative to ground Basis measurement parameter, such as capacitor, resistance, inductance, pressure are converted to the frequency of oscillation or spy of the probe signals easily measured The charge and discharge time in the cycle of oscillation of needle signal, and conversion module 223 is input in the form of analog signal.Conversion module 223 Convert analog signals into digital signal.Signal processing module 222 filters digital signal further progress.Above-mentioned detecting module 221 can carry out taking whether liquid successfully determines according to filtered digital signal.Detecting module 221 can also be used to take liquid in determination When success or failure, success notification message or failure notification message are generated and issued.Control module 225 can control probe motion, Stop and take liquid.Above-mentioned modules can also be by way of or function integrated function segmentation by more modules or less Module is realized, is not limited herein.
In one example, above-mentioned probe 21 can be the double-deck probe.The internal layer of the double-deck probe 21 tests circuit 22 with liquid is taken Connection, specifically, the internal layer of the double-deck probe 21 can be connect with the conditioning module 224 in liquid test circuit 22 is taken.The double-deck probe Outer layer is connect with reference.With reference to ground be with isolated from power internally.That is, being isolated with reference to ground with power ground.So that It takes the core in liquid test device 20 that liquid test circuit 22 is taken to be isolated with other equipment or component, prevents other equipment or portion Part bring interference signal brings adverse effect to taking liquid test process.Take liquid whether successful to further improve judgement Accuracy reduces judgement and takes the whether successful False Rate of liquid.
The embodiment of the invention also provides one kind to take liquid system, and it includes above-mentioned taking liquid test device and being used for that this, which takes liquid system, Placement holds the pallet 31 of liquid container (such as no liquid container).Wherein, pallet 31 is connect with reference.Specifically, pallet 31 can be metal tray.
In one example, 31 lower section of pallet can also successively stack downwards insulating layer 32 and instrument rack 33.Instrument rack It is connect with power ground.Specifically, instrument rack can be metal machine frame.Insulating layer 32 is for being isolated pallet 31 and instrument rack 33.
The outer layer of pallet 31 and the double-deck probe is all connected with reference to ground.Instrument rack connects power ground.With reference to ground and power ground It is isolated.To will further take the core in liquid test device 20 to take liquid test circuit 22 and periphery in taking liquid system Equipment, such as the isolation of instrument rack, prevent peripheral equipment bring interference signal to taking liquid test process to bring adverse effect.From And further improve judgement and take the whether successful accuracy of liquid, it reduces judgement and takes the whether successful False Rate of liquid.
The concrete function of liquid test device and beneficial effect is taken to can be found in the phase for taking liquid test method in above-described embodiment Specification specified content is closed, details are not described herein.
Take liquid test method and device can be by taking liquid to set in conjunction with Fig. 1 to Fig. 5 embodiment each according to the present invention described Standby 400 realize.Fig. 6 is the hardware structural diagram that one of embodiment of the present invention takes liquid equipment 400.
Taking liquid equipment 400 includes probe (not shown in FIG. 6), memory 401 and processor 402.It is deposited on memory 401 Contain the program that can be run on the processor 402.The program runs in processor 402 and can be achieved to take liquid to survey in above-described embodiment Method for testing.
In one example, above-mentioned processor 402 may include central processing unit (CPU) or specific integrated circuit (ASIC), or may be configured to implement the embodiment of the present application one or more integrated circuits.
Memory 401 may include the mass storage for data or instruction.For example it rather than limits, memory 401 may include HDD, floppy disk drive, flash memory, CD, magneto-optic disk, tape or universal serial bus (USB) driver or two The combination of a or more the above.In a suitable case, memory 401 may include that can be removed or non-removable (or solid Medium calmly).In a suitable case, memory 401 can take inside or outside liquid equipment 400.In a particular embodiment, Memory 401 is non-volatile solid state memory.In a particular embodiment, memory 401 includes read-only memory (ROM).? In suitable situation, which can be the ROM of masked edit program, programming ROM (PROM), erasable PROM (EPROM), electricity can Wipe PROM (EEPROM), electrically-alterable ROM (EAROM) or the combination of flash memory or two or more the above.
Processor 402 is run and executable program generation by reading the executable program code stored in memory 401 The corresponding program of code, to take liquid test method for executing in above-mentioned each embodiment.
In one example, liquid equipment 400 is taken to may also include communication interface 403 and bus 404.Wherein, as shown in fig. 6, Memory 401, processor 402, communication interface 403 connect by bus 404 and complete mutual communication.
Communication interface 403 is mainly used for realizing in the embodiment of the present application between each module, device, unit and/or equipment Communication.It can also the access input equipment of communication interface 403 and/or output equipment.
Bus 404 includes hardware, software or both, and the component of liquid equipment 400 will be taken to be coupled to each other together.For example Rather than limit, bus 404 may include accelerated graphics port (AGP) or other graphics bus, enhancing Industry Standard Architecture (EISA) Bus, front side bus (FSB), super transmission (HT) interconnection, the interconnection of Industry Standard Architecture (ISA) bus, infinite bandwidth, low pin count (LPC) bus, memory bus, micro- channel architecture (MCA) bus, peripheral component interconnection (PCI) bus, PCI-Express (PCI-X) bus, Serial Advanced Technology Attachment (SATA) bus, Video Electronics Standards Association part (VLB) bus or other conjunctions The combination of suitable bus or two or more the above.In a suitable case, bus 404 may include one or more Bus.Although specific bus has been described and illustrated in the embodiment of the present application, the application considers any suitable bus or interconnection.
One embodiment of the invention also provides a kind of storage medium, is stored with program on the storage medium, and the program is processed Device can be realized in above-mentioned each embodiment when executing takes liquid test method.
The various pieces of this specification are all made of progressive mode and are described, same and similar portion between each embodiment Dividing may refer to each other, and what each embodiment introduced is and other embodiments difference.Implement especially for device For example, apparatus embodiments and storage medium embodiment, since it is substantially similar to the method embodiment, so the comparison of description is simple It is single, referring to the explanation of embodiment of the method part in place of correlation.
More than, the only specific embodiment of the application, but the protection scope of the application is not limited thereto, and it is any to be familiar with Those skilled in the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all cover Within the protection scope of the application.Therefore, the protection scope of the application should be subject to the protection scope in claims.

Claims (10)

1. one kind takes liquid test method characterized by comprising
In the case where defaulting probe and taking the successful situation of liquid during once taking liquid, controls the probe and exist to the release of no liquid container It is described once to take the liquid got during liquid;
It controls the probe and carries out liquid level test in the no liquid container;
If the probe is touching liquid level within the scope of the no liquid container bottom preset height, the probe is verified in institute It states and takes liquid success during once taking liquid, the preset height range is obtained based on the expectation liquid-taken amount of the probe.
2. the method according to claim 1, wherein the control probe in the no liquid container into Row liquid level test, comprising:
Measurement parameter of the probe in no liquid container is repeatedly obtained, the measurement parameter is the ginseng for causing probe signals to change Number;
Measurement of comparison variable quantity and test judgement threshold value, the measurement variable quantity is the measurement parameter and upper one currently obtained The variable quantity of the measurement parameter of secondary acquisition.
3. according to the method described in claim 2, it is characterized in that, if the probe is default apart from the no liquid container bottom Liquid level is touched in altitude range, verify the probe it is described once take liquid during take liquid success, comprising:
If probe measurement variable quantity when within the scope of the no liquid container bottom preset height is greater than test and sentences Determine threshold value, then verify the probe it is described once take liquid during take liquid success.
4. the method according to claim 1, wherein further include:
If the probe, not in contact with liquid level is arrived, verifies the probe and exists within the scope of the no liquid container bottom preset height It is described that liquid is once taken to take liquid to fail in the process.
5. method as claimed in any of claims 1 to 4, which is characterized in that the measurement parameter includes capacitor, electricity It is resistance, inductance, pressure, one or more in the frequency of oscillation of probe signals.
6. one kind takes liquid test device, which is characterized in that including taking liquid test circuit and probe;
The probe is for taking liquid;
It is described that liquid test circuit is taken to be used in the case where defaulting probe and taking the successful situation of liquid during once taking liquid, control the spy Needle to no liquid container discharge it is described once take liquid during the liquid got;And for controlling the probe described Liquid level test is carried out in no liquid container;And if for the probe apart from the no liquid container bottom preset height model Liquid level is touched in enclosing, verify the probe it is described once take liquid during take liquid success, the preset height range is based on The expectation liquid-taken amount of the probe obtains.
7. device according to claim 6, which is characterized in that it is described take liquid test circuit include detecting module, the spy Module is surveyed to be used for:
Measurement parameter of the probe in no liquid container is repeatedly obtained, the measurement parameter is the ginseng for causing probe signals to change Number;
Measurement of comparison variable quantity and test judgement threshold value, the measurement variable quantity is the measurement parameter and upper one currently obtained The variable quantity of the measurement parameter of secondary acquisition.
8. device according to claim 7, which is characterized in that the detecting module is specifically used for:
If probe measurement variable quantity when within the scope of the no liquid container bottom preset height is greater than test and sentences Determine threshold value, then verify the probe it is described once take liquid during take liquid success.
9. device according to claim 6, which is characterized in that the detecting module is also used to:
If the probe, not in contact with liquid level is arrived, verifies the probe and exists within the scope of the no liquid container bottom preset height It is described that liquid is once taken to take liquid to fail in the process.
10. device according to claim 6, which is characterized in that the probe is the double-deck probe, wherein the double-deck spy The internal layer of needle takes liquid test circuit to be connected with described, and the outer layer of the bilayer probe is connect with reference, described with reference to ground and electricity Source it is isolated.
CN201810574198.2A 2018-06-06 2018-06-06 Take liquid test method and device Pending CN109030096A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112414506A (en) * 2020-11-11 2021-02-26 苏州长光华医生物医学工程有限公司 Reagent suction detection device and computer readable storage medium
CN114441238A (en) * 2020-11-04 2022-05-06 深圳市帝迈生物技术有限公司 Sampling device, analyzer and sampling method for analyzer

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060093525A1 (en) * 2004-05-14 2006-05-04 Roche Diagnostics Operations, Inc. Level sensor apparatus for detecting contact of a pipetting needle with a liquid in a vessel
CN101308158A (en) * 2007-05-15 2008-11-19 株式会社日立高新技术 Liquid separate injection device
CN101881706A (en) * 2010-07-05 2010-11-10 深圳迈瑞生物医疗电子股份有限公司 Sampling device and method
CN103748471A (en) * 2011-09-01 2014-04-23 株式会社日立高新技术 Autoanalyzer
CN105067080A (en) * 2015-08-06 2015-11-18 四川迈克生物医疗电子有限公司 Capacitive liquid level detection device, method and system
CN106324270A (en) * 2015-07-03 2017-01-11 西门子医学诊断产品有限责任公司 Method for touch detection for a pipetting needle
WO2017008249A1 (en) * 2015-07-14 2017-01-19 深圳迈瑞生物医疗电子股份有限公司 Sampling mechanism, skipped-vacuum testing method therefor, and sample analyzer

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060093525A1 (en) * 2004-05-14 2006-05-04 Roche Diagnostics Operations, Inc. Level sensor apparatus for detecting contact of a pipetting needle with a liquid in a vessel
CN101308158A (en) * 2007-05-15 2008-11-19 株式会社日立高新技术 Liquid separate injection device
CN101881706A (en) * 2010-07-05 2010-11-10 深圳迈瑞生物医疗电子股份有限公司 Sampling device and method
CN103748471A (en) * 2011-09-01 2014-04-23 株式会社日立高新技术 Autoanalyzer
CN106324270A (en) * 2015-07-03 2017-01-11 西门子医学诊断产品有限责任公司 Method for touch detection for a pipetting needle
WO2017008249A1 (en) * 2015-07-14 2017-01-19 深圳迈瑞生物医疗电子股份有限公司 Sampling mechanism, skipped-vacuum testing method therefor, and sample analyzer
CN105067080A (en) * 2015-08-06 2015-11-18 四川迈克生物医疗电子有限公司 Capacitive liquid level detection device, method and system

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114441238A (en) * 2020-11-04 2022-05-06 深圳市帝迈生物技术有限公司 Sampling device, analyzer and sampling method for analyzer
CN112414506A (en) * 2020-11-11 2021-02-26 苏州长光华医生物医学工程有限公司 Reagent suction detection device and computer readable storage medium

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