CN109007813A - 一种具有缓解视疲劳功能的口服液的制作方法 - Google Patents
一种具有缓解视疲劳功能的口服液的制作方法 Download PDFInfo
- Publication number
- CN109007813A CN109007813A CN201811035725.9A CN201811035725A CN109007813A CN 109007813 A CN109007813 A CN 109007813A CN 201811035725 A CN201811035725 A CN 201811035725A CN 109007813 A CN109007813 A CN 109007813A
- Authority
- CN
- China
- Prior art keywords
- juice
- mixed
- oral solution
- rice protein
- visual fatigue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 229940100688 oral solution Drugs 0.000 title claims abstract description 22
- 208000003464 asthenopia Diseases 0.000 title claims abstract description 19
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 6
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims abstract description 26
- 240000000851 Vaccinium corymbosum Species 0.000 claims abstract description 16
- 235000003095 Vaccinium corymbosum Nutrition 0.000 claims abstract description 16
- 235000017537 Vaccinium myrtillus Nutrition 0.000 claims abstract description 16
- 235000021014 blueberries Nutrition 0.000 claims abstract description 16
- 235000016709 nutrition Nutrition 0.000 claims abstract description 16
- 230000035764 nutrition Effects 0.000 claims abstract description 16
- 239000002002 slurry Substances 0.000 claims abstract description 16
- 235000003145 Hippophae rhamnoides Nutrition 0.000 claims abstract description 15
- 235000007164 Oryza sativa Nutrition 0.000 claims abstract description 14
- 235000009566 rice Nutrition 0.000 claims abstract description 14
- 235000005687 corn oil Nutrition 0.000 claims abstract description 11
- 239000002285 corn oil Substances 0.000 claims abstract description 11
- 239000007788 liquid Substances 0.000 claims abstract description 11
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract description 10
- 229930195729 fatty acid Natural products 0.000 claims abstract description 10
- 239000000194 fatty acid Substances 0.000 claims abstract description 10
- 240000006024 Lactobacillus plantarum Species 0.000 claims abstract description 9
- 235000013965 Lactobacillus plantarum Nutrition 0.000 claims abstract description 9
- 241000223254 Rhodotorula mucilaginosa Species 0.000 claims abstract description 9
- 229940072205 lactobacillus plantarum Drugs 0.000 claims abstract description 9
- 241000894006 Bacteria Species 0.000 claims abstract description 8
- 238000000855 fermentation Methods 0.000 claims abstract description 7
- 230000004151 fermentation Effects 0.000 claims abstract description 7
- 239000003531 protein hydrolysate Substances 0.000 claims abstract description 6
- 238000000034 method Methods 0.000 claims abstract description 5
- 230000001954 sterilising effect Effects 0.000 claims abstract description 5
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims abstract description 4
- 238000007789 sealing Methods 0.000 claims abstract description 4
- 230000003068 static effect Effects 0.000 claims abstract description 4
- 240000007594 Oryza sativa Species 0.000 claims abstract 6
- 240000000950 Hippophae rhamnoides Species 0.000 claims abstract 4
- 241000229143 Hippophae Species 0.000 claims description 14
- 239000000843 powder Substances 0.000 claims description 9
- 108090000623 proteins and genes Proteins 0.000 claims description 7
- 102000004169 proteins and genes Human genes 0.000 claims description 7
- 238000005303 weighing Methods 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 235000003935 Hippophae Nutrition 0.000 claims description 3
- 101000693530 Staphylococcus aureus Staphylokinase Proteins 0.000 claims description 3
- 235000013305 food Nutrition 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 235000019774 Rice Bran oil Nutrition 0.000 claims 1
- 239000010977 jade Substances 0.000 claims 1
- 235000015097 nutrients Nutrition 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 239000008165 rice bran oil Substances 0.000 claims 1
- 235000013399 edible fruits Nutrition 0.000 abstract description 4
- 235000009508 confectionery Nutrition 0.000 abstract description 2
- 230000035622 drinking Effects 0.000 abstract description 2
- 235000013402 health food Nutrition 0.000 abstract description 2
- 238000001816 cooling Methods 0.000 abstract 1
- 210000001508 eye Anatomy 0.000 description 23
- 208000024891 symptom Diseases 0.000 description 16
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 description 9
- 241000209094 Oryza Species 0.000 description 8
- 229930003944 flavone Natural products 0.000 description 7
- 235000011949 flavones Nutrition 0.000 description 7
- 230000006870 function Effects 0.000 description 7
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 6
- 230000004438 eyesight Effects 0.000 description 5
- 150000002213 flavones Chemical class 0.000 description 5
- 239000002994 raw material Substances 0.000 description 5
- OGNSCSPNOLGXSM-UHFFFAOYSA-N (+/-)-DABA Natural products NCCC(N)C(O)=O OGNSCSPNOLGXSM-UHFFFAOYSA-N 0.000 description 4
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 4
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 4
- 206010034960 Photophobia Diseases 0.000 description 4
- 206010047513 Vision blurred Diseases 0.000 description 4
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 4
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 4
- 229960003692 gamma aminobutyric acid Drugs 0.000 description 4
- 230000035807 sensation Effects 0.000 description 4
- 235000019615 sensations Nutrition 0.000 description 4
- 235000019155 vitamin A Nutrition 0.000 description 4
- 239000011719 vitamin A Substances 0.000 description 4
- 229940045997 vitamin a Drugs 0.000 description 4
- JEBFVOLFMLUKLF-IFPLVEIFSA-N Astaxanthin Natural products CC(=C/C=C/C(=C/C=C/C1=C(C)C(=O)C(O)CC1(C)C)/C)C=CC=C(/C)C=CC=C(/C)C=CC2=C(C)C(=O)C(O)CC2(C)C JEBFVOLFMLUKLF-IFPLVEIFSA-N 0.000 description 3
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 3
- 229930003268 Vitamin C Natural products 0.000 description 3
- 235000013793 astaxanthin Nutrition 0.000 description 3
- 239000001168 astaxanthin Substances 0.000 description 3
- MQZIGYBFDRPAKN-ZWAPEEGVSA-N astaxanthin Chemical compound C([C@H](O)C(=O)C=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C(=O)[C@@H](O)CC1(C)C MQZIGYBFDRPAKN-ZWAPEEGVSA-N 0.000 description 3
- 229940022405 astaxanthin Drugs 0.000 description 3
- 210000005252 bulbus oculi Anatomy 0.000 description 3
- 230000005779 cell damage Effects 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 239000003889 eye drop Substances 0.000 description 3
- 229940012356 eye drops Drugs 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 230000004060 metabolic process Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 235000019154 vitamin C Nutrition 0.000 description 3
- 239000011718 vitamin C Substances 0.000 description 3
- 102000040350 B family Human genes 0.000 description 2
- 108091072128 B family Proteins 0.000 description 2
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 description 2
- 229930003427 Vitamin E Natural products 0.000 description 2
- 230000003078 antioxidant effect Effects 0.000 description 2
- 102000006995 beta-Glucosidase Human genes 0.000 description 2
- 108010047754 beta-Glucosidase Proteins 0.000 description 2
- -1 by measurement Chemical class 0.000 description 2
- 208000037887 cell injury Diseases 0.000 description 2
- 210000004087 cornea Anatomy 0.000 description 2
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 2
- 229930182478 glucoside Natural products 0.000 description 2
- 150000008131 glucosides Chemical class 0.000 description 2
- 229930182470 glycoside Natural products 0.000 description 2
- 210000001328 optic nerve Anatomy 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- 230000002335 preservative effect Effects 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 239000011782 vitamin Substances 0.000 description 2
- 229940088594 vitamin Drugs 0.000 description 2
- 235000019165 vitamin E Nutrition 0.000 description 2
- 229940046009 vitamin E Drugs 0.000 description 2
- 239000011709 vitamin E Substances 0.000 description 2
- 150000003722 vitamin derivatives Chemical class 0.000 description 2
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 2
- 208000028006 Corneal injury Diseases 0.000 description 1
- 206010057315 Daydreaming Diseases 0.000 description 1
- 208000003164 Diplopia Diseases 0.000 description 1
- 206010015958 Eye pain Diseases 0.000 description 1
- 206010020565 Hyperaemia Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 229930014669 anthocyanidin Natural products 0.000 description 1
- 150000001452 anthocyanidin derivatives Chemical class 0.000 description 1
- 235000008758 anthocyanidins Nutrition 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 235000021466 carotenoid Nutrition 0.000 description 1
- 150000001747 carotenoids Chemical class 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 235000006694 eating habits Nutrition 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 208000030533 eye disease Diseases 0.000 description 1
- 210000000744 eyelid Anatomy 0.000 description 1
- 206010016256 fatigue Diseases 0.000 description 1
- 150000002212 flavone derivatives Chemical class 0.000 description 1
- 229930182486 flavonoid glycoside Natural products 0.000 description 1
- 150000007955 flavonoid glycosides Chemical class 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 235000013376 functional food Nutrition 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- 230000002607 hemopoietic effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000004410 intraocular pressure Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 235000012680 lutein Nutrition 0.000 description 1
- 239000001656 lutein Substances 0.000 description 1
- KBPHJBAIARWVSC-RGZFRNHPSA-N lutein Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\[C@H]1C(C)=C[C@H](O)CC1(C)C KBPHJBAIARWVSC-RGZFRNHPSA-N 0.000 description 1
- 229960005375 lutein Drugs 0.000 description 1
- ORAKUVXRZWMARG-WZLJTJAWSA-N lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C ORAKUVXRZWMARG-WZLJTJAWSA-N 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000009629 microbiological culture Methods 0.000 description 1
- 210000003061 neural cell Anatomy 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 230000004792 oxidative damage Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 210000000608 photoreceptor cell Anatomy 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000007065 protein hydrolysis Effects 0.000 description 1
- 210000001525 retina Anatomy 0.000 description 1
- 230000002207 retinal effect Effects 0.000 description 1
- 239000000790 retinal pigment Substances 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- KBPHJBAIARWVSC-XQIHNALSSA-N trans-lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C KBPHJBAIARWVSC-XQIHNALSSA-N 0.000 description 1
- 230000000472 traumatic effect Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- FJHBOVDFOQMZRV-XQIHNALSSA-N xanthophyll Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C=C(C)C(O)CC2(C)C FJHBOVDFOQMZRV-XQIHNALSSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/09—Mashed or comminuted products, e.g. pulp, purée, sauce, or products made therefrom, e.g. snacks
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Botany (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
本发明公开了一种具有缓解视疲劳功能的口服液的制作方法,属于保健食品加工技术领域。先制备大米蛋白水解液、沙棘果汁和蓝莓果汁,将大米蛋白水解液、沙棘果汁和蓝莓果汁混合均匀得混合汁,将混合汁灭菌、降温,接入胶红酵母摇床培养4‑6小时后再接入植物乳杆菌静止发酵18‑24小时得混合菌种发酵液,混合菌种发酵液经酵母破壁均质机均质后得营养浆液,将溶有单脂肪酸甘油酯的玉米油加入到营养浆液中,经调配、均质、灌装、封口、灭菌即得成品。本发明的口服液不仅口感好、果香浓郁、饮用安全,而且具有显著的缓解视疲劳功能。
Description
技术领域
本发明公开了一种具有缓解视疲劳功能的口服液的制作方法,属于保健食品加工技术领域。
背景技术
视疲劳是指用眼工作时产生的主观症状的综合症,是目前眼科常见的一种疾病,患者的症状多种多样,有眼疲劳、眼干涩、异物感、眼皮沉重感、视物模糊、畏光流泪、眼球干涩、眼胀痛及眼部充血等,严重者还可出现头昏、精神萎靡、注意力不集中,少数患者可出现复视、立体视觉功能障碍、眼压升高、角膜损害等。随着现代工作、学习、生活节奏加快,电视、电子计算机的普及应用,人类使用视力的时问不断延长,而视物的距离相对缩短以及受自然生态环境日益恶化的影响,视疲劳已成为目前眼科常见的临床症候之一。视疲劳给患者的工作、学习及生活带来诸多不便,直接影响了学习、工作效率和生活质量,目前用于缓解视疲劳的外用滴眼液并不能根治视疲劳,而且超过九成外用滴眼液都含有防腐剂,如果长期使用含防腐剂的外用滴眼液,会造成眼表损伤,所以开发缓解视疲劳的功能食品相当重要。
发明内容
本发明的目的是提供一种口感好、果香浓郁、饮用安全的具有缓解视疲劳功能的口服液的制作方法。
本发明的目的是这样实现的:
称取一定质量的食用级大米蛋白粉,加7-9倍质量的清水调浆,按每克大米蛋白粉80-100个单位的比例加入中性蛋白酶,在45-50℃条件下酶解4-5小时后过滤得大米蛋白水解液。
将沙棘果洗净、榨汁后得沙棘果汁,将蓝莓洗净、榨汁后得蓝莓果汁,按照质量比1:2:2的比例将大米蛋白水解液、沙棘果汁和蓝莓果汁混合均匀得混合汁,将混合汁在85-90℃条件下灭菌10分钟,降温到26-28℃,从斜面上接入胶红酵母,在26-28℃、160-200rpm的条件下摇床培养4-6小时,然后加入0.01%的植物乳杆菌冻干粉,置于恒温箱中,在30-32℃条件下静止发酵18-24小时得混合菌种发酵液,混合菌种发酵液经酵母破壁均质机均质后得营养浆液。
称取一定质量的营养浆液,称取营养浆液质量0.05%单脂肪酸甘油酯,再称取营养浆液质量6%的玉米油,先将单脂肪酸甘油酯溶解到玉米油中,再将溶有单脂肪酸甘油酯的玉米油加入到营养浆液中,经调配、均质、灌装、封口、灭菌即得成品。
本发明的口服液有益效果包括以下几个方面:
第一,本发明的口服液的原料经过了胶红酵母的发酵,产生了大量的虾青素,经测定,每升本发明实施例的口服液中含虾青素4.33毫克,虾青素是一种超强的抗氧化剂,对眼睛的抗氧化效果是叶黄素的200倍,它能防止眼睛遭受光损伤、光感受器细胞损伤、神经节细胞损伤、神经细胞损伤和炎症损伤,是保护眼睛的最好补充剂。
第二,本发明的口服液的原料经过了植物乳杆菌的发酵,不仅口感酸爽、风味独特,还产生了包括维生素A、维生素C、维生素E和B族维生素在内的多种维生素,其中维生素A是构成视网膜表面的感光物质,有助于解除眼疲劳,增强眼部血液循环,改善视机能,维生素C可减弱紫外线与氧气对眼睛晶状体的损害,维生素E是抗氧化物,它能减少眼球中的自由基,延缓眼睛老化,B族维生素关系着视神经的健康,也有保护角膜的作用。
第三,本发明的口服液的原料含有蓝莓,蓝莓中的花青素具有活化视网膜功效,可以强化视力,防止眼球疲劳,另外蓝莓中的维生素C具有保护眼睛晶状体的作用。
第四,本发明的口服液的原料含有沙棘,沙棘中的维生素A、维生素C和类胡萝卜素等对促进眼睛健康至关重要,可以缓解眼睛干涩,沙棘中的黄酮对氧化损伤视网膜色素上皮细胞具有保护作用,是缓解视疲劳的重要功效成分,另外,沙棘中的沙棘黄酮大部分以糖苷的形式存在,不易被人体吸收,胶红酵母和植物乳杆菌代谢产生的β-葡萄糖苷酶可以将沙棘中的糖苷型黄酮转化成苷元型黄酮,苷元型黄酮不仅易被人体吸收,而且其生理活性也比其相应的糖苷型黄酮高,经过测定,本发明实施例的口服液中黄酮糖苷转化成黄酮苷元的转化率为90%。
第五,本发明的口服液含有植物乳杆菌代谢产生的γ-氨基丁酸,用“QB/T4587-2013γ-氨基丁酸”的方法对本发明实施例的口服液中的γ-氨基丁酸的含量进行测定,结果为16.01mg/100ml,γ-氨基丁酸不但能放松视神经,还能有效缓解由于缺乏γ-氨基丁酸而引起的视神经细胞退化、视觉能力下降。
第六,本发明的口服液具有浓郁的水果香气,沙棘果汁和蓝莓果汁经过胶红酵母和植物乳杆菌发酵后,胶红酵母和植物乳杆菌代谢产生的β-葡萄糖苷酶可以将沙棘和蓝莓中的结合态呈香物质转化成游离态呈香物质,增加本发明口服液的香气。
第七,本发明的口服液的原料含有玉米油,玉米油中维生素A含量丰富,对于缓解视疲劳具有积极的作用。
具体实施方式
本发明采用的胶红酵母CICC31429采购于中国工业微生物菌种保藏管理中心。
称取一定质量的食用级大米蛋白粉,加8倍质量的清水调浆,按每克大米蛋白粉90个单位的比例加入中性蛋白酶,在48℃条件下酶解4.5小时后过滤得大米蛋白水解液。
将沙棘果洗净、榨汁后得沙棘果汁,将蓝莓洗净、榨汁后得蓝莓果汁,按照质量比1:2:2的比例将大米蛋白水解液、沙棘果汁和蓝莓果汁混合均匀得混合汁,将混合汁在90℃条件下灭菌10分钟,降温到27℃,从斜面上接入胶红酵母,在27℃、180rpm的条件下摇床培养5小时,然后加入0.01%的植物乳杆菌冻干粉,置于恒温箱中,在31℃条件下静止发酵21小时得混合菌种发酵液,混合菌种发酵液经酵母破壁均质机均质后得营养浆液。
称取一定质量的营养浆液,称取营养浆液质量0.05%单脂肪酸甘油酯,再称取营养浆液质量6%的玉米油,先将单脂肪酸甘油酯溶解到玉米油中,再将溶有单脂肪酸甘油酯的玉米油加入到营养浆液中,经调配、均质、灌装、封口、灭菌即得成品。
本发明口服液实施效果试验:
受试对象:受试对象共计38人,都是长期用眼,视力易疲劳者,男女比例1:1,年龄为18岁-65岁,所有受试对象均不同程度具有眼酸痛、眼胀、畏光、视物模糊、眼干涩、异物感、流泪等7种症状中的一种或多种,在38名受试对象中具有眼酸痛症状者18人、具有眼胀症状者26人、具有畏光症状者7人、具有视物模糊症状者13人、具有眼干涩症状者38人、具有异物感症状者19人、具有流泪症状者22人,所有受试对象无以下情况:
1 患有感染性、外伤性眼部疾,进行眼部手术不足3个月;
2 患有角膜、晶体、玻璃体、眼底病变等内外眼疾;
3 患有心血管、脑血管、肝、肾、造血***等疾病;
4 正处于妊娠或哺乳期;
5 短期内服用与受试功能有关的物品,影响到对结果的判定;
6 长期服用有关治疗视力的药物,保健品或使用其他治疗方法未能终止;
7 具有过敏体质;
试验方法:受试对象每天饮用本发明实施例口服液50毫升,连续服用2个月。试验期间不改变原来的生活方式和饮食习惯。
试验结果判定标准:
1 显效:症状消失或明显减轻;
2 有效:症状略有减轻;
3 无效:症状无变化或加重;
试验结果见表一:
表一:受试对象各种视疲劳症状改善情况表
序号 | 症状类型 | 症状人数 | 显效人数 | 有效人数 | 无效人数 | 总有效率 |
1 | 眼酸痛 | 18 | 3 | 10 | 5 | 72.2% |
2 | 眼胀 | 26 | 7 | 12 | 7 | 73.1% |
3 | 畏光 | 7 | 2 | 3 | 2 | 71.4% |
4 | 视物模糊 | 13 | 3 | 5 | 5 | 61.5% |
5 | 眼干涩 | 38 | 9 | 22 | 7 | 81.6% |
6 | 异物感 | 19 | 4 | 9 | 6 | 68.4% |
7 | 流泪 | 22 | 5 | 12 | 5 | 77.3% |
从上表可以看出,本发明实施例的口服液对视疲劳有明显的改善作用。
Claims (1)
1.一种具有缓解视疲劳功能的口服液的制作方法,其特征是经过如下加工过程制备而成:
⑴称取一定质量的食用级大米蛋白粉,加7-9倍质量的清水调浆,按每克大米蛋白粉80-100个单位的比例加入中性蛋白酶,在45-50℃条件下酶解4-5小时后过滤得大米蛋白水解液;
⑵将沙棘果洗净、榨汁后得沙棘果汁,将蓝莓洗净、榨汁后得蓝莓果汁,按照质量比1:2:2的比例将大米蛋白水解液、沙棘果汁和蓝莓果汁混合均匀得混合汁,将混合汁在85-90℃条件下灭菌10分钟,降温到26-28℃,从斜面上接入胶红酵母,在26-28℃、160-200rpm的条件下摇床培养4-6小时,然后加入0.01%的植物乳杆菌冻干粉,置于恒温箱中,在30-32℃条件下静止发酵18-24小时得混合菌种发酵液,混合菌种发酵液经酵母破壁均质机均质后得营养浆液;
⑶称取一定质量的营养浆液,称取营养浆液质量0.05%单脂肪酸甘油酯,再称取营养浆液质量6%的玉米油,先将单脂肪酸甘油酯溶解到玉米油中,再将溶有单脂肪酸甘油酯的玉米油加入到营养浆液中,经调配、均质、灌装、封口、灭菌即得成品。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201811035725.9A CN109007813A (zh) | 2018-09-06 | 2018-09-06 | 一种具有缓解视疲劳功能的口服液的制作方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201811035725.9A CN109007813A (zh) | 2018-09-06 | 2018-09-06 | 一种具有缓解视疲劳功能的口服液的制作方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN109007813A true CN109007813A (zh) | 2018-12-18 |
Family
ID=64624285
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201811035725.9A Withdrawn CN109007813A (zh) | 2018-09-06 | 2018-09-06 | 一种具有缓解视疲劳功能的口服液的制作方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN109007813A (zh) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101225418A (zh) * | 2008-02-19 | 2008-07-23 | 中南林业科技大学 | 一种以稻米为原料制取γ-氨基丁酸的方法 |
CN104186654A (zh) * | 2014-08-04 | 2014-12-10 | 哈尔滨伟平科技开发有限公司 | 一种具有补钙作用的香菇保健乳饮料的制作方法 |
CN106213095A (zh) * | 2016-06-30 | 2016-12-14 | 恒枫食品科技有限公司 | 一种发酵果蔬汁的制备方法及其得到产品的应用 |
-
2018
- 2018-09-06 CN CN201811035725.9A patent/CN109007813A/zh not_active Withdrawn
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101225418A (zh) * | 2008-02-19 | 2008-07-23 | 中南林业科技大学 | 一种以稻米为原料制取γ-氨基丁酸的方法 |
CN104186654A (zh) * | 2014-08-04 | 2014-12-10 | 哈尔滨伟平科技开发有限公司 | 一种具有补钙作用的香菇保健乳饮料的制作方法 |
CN106213095A (zh) * | 2016-06-30 | 2016-12-14 | 恒枫食品科技有限公司 | 一种发酵果蔬汁的制备方法及其得到产品的应用 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102048201B (zh) | 一种新的果蔬饮品 | |
CN106333885A (zh) | 一种植物提取物及眼部精华液 | |
CN102763847B (zh) | 一种具有缓解视疲劳的保健食品及其制备方法 | |
CN102742656B (zh) | 一种缓解视力疲劳的奶茶及其制备方法 | |
CN103977157A (zh) | 黑枸杞明目的护眼茶 | |
CN101248878A (zh) | 营养视神经的保健食品及其制备方法 | |
CN105505635A (zh) | 一种含有荷花活性成分的洁肤组合物及其制备方法 | |
JP4658290B2 (ja) | 線維芽細胞増殖作用剤、美容用飲食品および皮膚化粧料 | |
CN104432036A (zh) | 缓解视疲劳的保健营养组合物及其制备方法与应用 | |
CN102885359A (zh) | 一种新的果蔬饮品 | |
CN108159036A (zh) | 含茶氨酸、磷脂酰丝氨酸和原花青素的缓解视疲劳的组合物 | |
EP2564858A1 (en) | Composition for the treatment of aesthenopia | |
CN108354918A (zh) | 含茶氨酸、γ-氨基丁酸和原花青素的缓解视疲劳的组合物 | |
CN108042652A (zh) | 含枸杞、菊花和γ-氨基丁酸的缓解视疲劳的组合物 | |
CN102894435A (zh) | 一种缓解视疲劳的桑杞饮料及其制备方法 | |
CN107736532A (zh) | 一种缓解体力疲劳的人参饮品及其制备方法 | |
CN101757299A (zh) | 一种缓解视疲劳产品及其制备方法 | |
CN111513110A (zh) | 含有叶黄素的蓝莓护眼饼干及其制备方法 | |
CN106578323A (zh) | 一种改善视力的功能性冰淇淋及其制备方法 | |
CN109007813A (zh) | 一种具有缓解视疲劳功能的口服液的制作方法 | |
KR20160142965A (ko) | 멀꿀을 첨가한 음료 및 그 제조방법 | |
CN102488266A (zh) | 叶黄素木糖醇营养饮品及其制备方法 | |
CN108210640A (zh) | 含茶叶提取物的缓解视疲劳组合物 | |
CN108078974A (zh) | 含茶氨酸、γ-氨基丁酸和虾青素的缓解视疲劳的组合物 | |
CN103828985A (zh) | 一种银杏红枣茶 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WW01 | Invention patent application withdrawn after publication | ||
WW01 | Invention patent application withdrawn after publication |
Application publication date: 20181218 |