CN109007813A - 一种具有缓解视疲劳功能的口服液的制作方法 - Google Patents
一种具有缓解视疲劳功能的口服液的制作方法 Download PDFInfo
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Abstract
本发明公开了一种具有缓解视疲劳功能的口服液的制作方法，属于保健食品加工技术领域。先制备大米蛋白水解液、沙棘果汁和蓝莓果汁，将大米蛋白水解液、沙棘果汁和蓝莓果汁混合均匀得混合汁，将混合汁灭菌、降温，接入胶红酵母摇床培养4‑6小时后再接入植物乳杆菌静止发酵18‑24小时得混合菌种发酵液，混合菌种发酵液经酵母破壁均质机均质后得营养浆液，将溶有单脂肪酸甘油酯的玉米油加入到营养浆液中，经调配、均质、灌装、封口、灭菌即得成品。本发明的口服液不仅口感好、果香浓郁、饮用安全，而且具有显著的缓解视疲劳功能。
Description
技术领域
本发明公开了一种具有缓解视疲劳功能的口服液的制作方法，属于保健食品加工技术领域。
背景技术
视疲劳是指用眼工作时产生的主观症状的综合症，是目前眼科常见的一种疾病，患者的症状多种多样，有眼疲劳、眼干涩、异物感、眼皮沉重感、视物模糊、畏光流泪、眼球干涩、眼胀痛及眼部充血等，严重者还可出现头昏、精神萎靡、注意力不集中，少数患者可出现复视、立体视觉功能障碍、眼压升高、角膜损害等。随着现代工作、学习、生活节奏加快，电视、电子计算机的普及应用，人类使用视力的时问不断延长，而视物的距离相对缩短以及受自然生态环境日益恶化的影响，视疲劳已成为目前眼科常见的临床症候之一。视疲劳给患者的工作、学习及生活带来诸多不便，直接影响了学习、工作效率和生活质量，目前用于缓解视疲劳的外用滴眼液并不能根治视疲劳，而且超过九成外用滴眼液都含有防腐剂，如果长期使用含防腐剂的外用滴眼液，会造成眼表损伤，所以开发缓解视疲劳的功能食品相当重要。
发明内容
本发明的目的是提供一种口感好、果香浓郁、饮用安全的具有缓解视疲劳功能的口服液的制作方法。
本发明的目的是这样实现的：
称取一定质量的食用级大米蛋白粉，加7-9倍质量的清水调浆，按每克大米蛋白粉80-100个单位的比例加入中性蛋白酶，在45-50℃条件下酶解4-5小时后过滤得大米蛋白水解液。
将沙棘果洗净、榨汁后得沙棘果汁，将蓝莓洗净、榨汁后得蓝莓果汁，按照质量比1:2:2的比例将大米蛋白水解液、沙棘果汁和蓝莓果汁混合均匀得混合汁，将混合汁在85-90℃条件下灭菌10分钟，降温到26-28℃，从斜面上接入胶红酵母，在26-28℃、160-200rpm的条件下摇床培养4-6小时，然后加入0.01%的植物乳杆菌冻干粉，置于恒温箱中，在30-32℃条件下静止发酵18-24小时得混合菌种发酵液，混合菌种发酵液经酵母破壁均质机均质后得营养浆液。
称取一定质量的营养浆液，称取营养浆液质量0.05%单脂肪酸甘油酯，再称取营养浆液质量6%的玉米油，先将单脂肪酸甘油酯溶解到玉米油中，再将溶有单脂肪酸甘油酯的玉米油加入到营养浆液中，经调配、均质、灌装、封口、灭菌即得成品。
本发明的口服液有益效果包括以下几个方面：
第一，本发明的口服液的原料经过了胶红酵母的发酵，产生了大量的虾青素，经测定，每升本发明实施例的口服液中含虾青素4.33毫克，虾青素是一种超强的抗氧化剂，对眼睛的抗氧化效果是叶黄素的200倍，它能防止眼睛遭受光损伤、光感受器细胞损伤、神经节细胞损伤、神经细胞损伤和炎症损伤,是保护眼睛的最好补充剂。
第二，本发明的口服液的原料经过了植物乳杆菌的发酵，不仅口感酸爽、风味独特，还产生了包括维生素A、维生素C、维生素E和B族维生素在内的多种维生素，其中维生素A是构成视网膜表面的感光物质，有助于解除眼疲劳，增强眼部血液循环，改善视机能，维生素C可减弱紫外线与氧气对眼睛晶状体的损害，维生素E是抗氧化物，它能减少眼球中的自由基，延缓眼睛老化，B族维生素关系着视神经的健康，也有保护角膜的作用。
第三，本发明的口服液的原料含有蓝莓，蓝莓中的花青素具有活化视网膜功效，可以强化视力，防止眼球疲劳，另外蓝莓中的维生素C具有保护眼睛晶状体的作用。
第四，本发明的口服液的原料含有沙棘，沙棘中的维生素A、维生素C和类胡萝卜素等对促进眼睛健康至关重要，可以缓解眼睛干涩，沙棘中的黄酮对氧化损伤视网膜色素上皮细胞具有保护作用，是缓解视疲劳的重要功效成分，另外，沙棘中的沙棘黄酮大部分以糖苷的形式存在，不易被人体吸收，胶红酵母和植物乳杆菌代谢产生的β-葡萄糖苷酶可以将沙棘中的糖苷型黄酮转化成苷元型黄酮，苷元型黄酮不仅易被人体吸收，而且其生理活性也比其相应的糖苷型黄酮高，经过测定，本发明实施例的口服液中黄酮糖苷转化成黄酮苷元的转化率为90%。
第五，本发明的口服液含有植物乳杆菌代谢产生的γ-氨基丁酸，用“QB/T4587-2013γ-氨基丁酸”的方法对本发明实施例的口服液中的γ-氨基丁酸的含量进行测定，结果为16.01mg/100ml，γ-氨基丁酸不但能放松视神经，还能有效缓解由于缺乏γ-氨基丁酸而引起的视神经细胞退化、视觉能力下降。
第六，本发明的口服液具有浓郁的水果香气，沙棘果汁和蓝莓果汁经过胶红酵母和植物乳杆菌发酵后，胶红酵母和植物乳杆菌代谢产生的β-葡萄糖苷酶可以将沙棘和蓝莓中的结合态呈香物质转化成游离态呈香物质，增加本发明口服液的香气。
第七，本发明的口服液的原料含有玉米油，玉米油中维生素A含量丰富，对于缓解视疲劳具有积极的作用。
具体实施方式
本发明采用的胶红酵母CICC31429采购于中国工业微生物菌种保藏管理中心。
称取一定质量的食用级大米蛋白粉，加8倍质量的清水调浆，按每克大米蛋白粉90个单位的比例加入中性蛋白酶，在48℃条件下酶解4.5小时后过滤得大米蛋白水解液。
将沙棘果洗净、榨汁后得沙棘果汁，将蓝莓洗净、榨汁后得蓝莓果汁，按照质量比1:2:2的比例将大米蛋白水解液、沙棘果汁和蓝莓果汁混合均匀得混合汁，将混合汁在90℃条件下灭菌10分钟，降温到27℃，从斜面上接入胶红酵母，在27℃、180rpm的条件下摇床培养5小时，然后加入0.01%的植物乳杆菌冻干粉，置于恒温箱中，在31℃条件下静止发酵21小时得混合菌种发酵液，混合菌种发酵液经酵母破壁均质机均质后得营养浆液。
称取一定质量的营养浆液，称取营养浆液质量0.05%单脂肪酸甘油酯，再称取营养浆液质量6%的玉米油，先将单脂肪酸甘油酯溶解到玉米油中，再将溶有单脂肪酸甘油酯的玉米油加入到营养浆液中，经调配、均质、灌装、封口、灭菌即得成品。
本发明口服液实施效果试验：
受试对象：受试对象共计38人，都是长期用眼，视力易疲劳者，男女比例1:1，年龄为18岁－65岁，所有受试对象均不同程度具有眼酸痛、眼胀、畏光、视物模糊、眼干涩、异物感、流泪等7种症状中的一种或多种，在38名受试对象中具有眼酸痛症状者18人、具有眼胀症状者26人、具有畏光症状者7人、具有视物模糊症状者13人、具有眼干涩症状者38人、具有异物感症状者19人、具有流泪症状者22人，所有受试对象无以下情况：
1 患有感染性、外伤性眼部疾，进行眼部手术不足3个月；
2 患有角膜、晶体、玻璃体、眼底病变等内外眼疾；
3 患有心血管、脑血管、肝、肾、造血***等疾病；
4 正处于妊娠或哺乳期；
5 短期内服用与受试功能有关的物品，影响到对结果的判定；
6 长期服用有关治疗视力的药物，保健品或使用其他治疗方法未能终止；
7 具有过敏体质；
试验方法：受试对象每天饮用本发明实施例口服液50毫升，连续服用2个月。试验期间不改变原来的生活方式和饮食习惯。
试验结果判定标准：
1 显效：症状消失或明显减轻；
2 有效：症状略有减轻；
3 无效：症状无变化或加重；
试验结果见表一：
表一：受试对象各种视疲劳症状改善情况表
| 序号 | 症状类型 | 症状人数 | 显效人数 | 有效人数 | 无效人数 | 总有效率 |
| 1 | 眼酸痛 | 18 | 3 | 10 | 5 | 72.2% |
| 2 | 眼胀 | 26 | 7 | 12 | 7 | 73.1% |
| 3 | 畏光 | 7 | 2 | 3 | 2 | 71.4% |
| 4 | 视物模糊 | 13 | 3 | 5 | 5 | 61.5% |
| 5 | 眼干涩 | 38 | 9 | 22 | 7 | 81.6% |
| 6 | 异物感 | 19 | 4 | 9 | 6 | 68.4% |
| 7 | 流泪 | 22 | 5 | 12 | 5 | 77.3% |
从上表可以看出，本发明实施例的口服液对视疲劳有明显的改善作用。
Claims (1)
1.一种具有缓解视疲劳功能的口服液的制作方法，其特征是经过如下加工过程制备而成：
⑴称取一定质量的食用级大米蛋白粉，加7-9倍质量的清水调浆，按每克大米蛋白粉80-100个单位的比例加入中性蛋白酶，在45-50℃条件下酶解4-5小时后过滤得大米蛋白水解液；
⑵将沙棘果洗净、榨汁后得沙棘果汁，将蓝莓洗净、榨汁后得蓝莓果汁，按照质量比1:2:2的比例将大米蛋白水解液、沙棘果汁和蓝莓果汁混合均匀得混合汁，将混合汁在85-90℃条件下灭菌10分钟，降温到26-28℃，从斜面上接入胶红酵母，在26-28℃、160-200rpm的条件下摇床培养4-6小时，然后加入0.01%的植物乳杆菌冻干粉，置于恒温箱中，在30-32℃条件下静止发酵18-24小时得混合菌种发酵液，混合菌种发酵液经酵母破壁均质机均质后得营养浆液；
⑶称取一定质量的营养浆液，称取营养浆液质量0.05%单脂肪酸甘油酯，再称取营养浆液质量6%的玉米油，先将单脂肪酸甘油酯溶解到玉米油中，再将溶有单脂肪酸甘油酯的玉米油加入到营养浆液中，经调配、均质、灌装、封口、灭菌即得成品。
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| CN101225418A (zh) * | 2008-02-19 | 2008-07-23 | 中南林业科技大学 | 一种以稻米为原料制取γ-氨基丁酸的方法 |
| CN104186654A (zh) * | 2014-08-04 | 2014-12-10 | 哈尔滨伟平科技开发有限公司 | 一种具有补钙作用的香菇保健乳饮料的制作方法 |
| CN106213095A (zh) * | 2016-06-30 | 2016-12-14 | 恒枫食品科技有限公司 | 一种发酵果蔬汁的制备方法及其得到产品的应用 |
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| CN101225418A (zh) * | 2008-02-19 | 2008-07-23 | 中南林业科技大学 | 一种以稻米为原料制取γ-氨基丁酸的方法 |
| CN104186654A (zh) * | 2014-08-04 | 2014-12-10 | 哈尔滨伟平科技开发有限公司 | 一种具有补钙作用的香菇保健乳饮料的制作方法 |
| CN106213095A (zh) * | 2016-06-30 | 2016-12-14 | 恒枫食品科技有限公司 | 一种发酵果蔬汁的制备方法及其得到产品的应用 |
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