CN108992211B - Method for manufacturing titanium mesh for alveolar bone defect - Google Patents

Method for manufacturing titanium mesh for alveolar bone defect Download PDF

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CN108992211B
CN108992211B CN201810820741.2A CN201810820741A CN108992211B CN 108992211 B CN108992211 B CN 108992211B CN 201810820741 A CN201810820741 A CN 201810820741A CN 108992211 B CN108992211 B CN 108992211B
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titanium mesh
data
positioning
titanium
bone defect
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CN108992211A (en
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杨静文
刘琦
张海东
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Peking University School of Stomatology
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Peking University School of Stomatology
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2/2846Support means for bone substitute or for bone graft implants, e.g. membranes or plates for covering bone defects
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2/2875Skull or cranium
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00Processes of additive manufacturing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2/2846Support means for bone substitute or for bone graft implants, e.g. membranes or plates for covering bone defects
    • A61F2002/285Fixation appliances for attaching bone substitute support means to underlying bone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2240/00Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2240/001Designing or manufacturing processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00011Metals or alloys
    • A61F2310/00023Titanium or titanium-based alloys, e.g. Ti-Ni alloys

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Veterinary Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Materials Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Neurosurgery (AREA)
  • Surgical Instruments (AREA)
  • Prostheses (AREA)

Abstract

A method for manufacturing a titanium mesh for alveolar bone defect relates to the field of titanium mesh manufacturing, and comprises the following steps: step 1: synthesizing dentition and jaw bone 3D model data according to the dentition data and jaw bone data; step 2: generating titanium mesh three-dimensional data covering the bone defect structure according to the bone defect structure; and step 3: generating a positioning wing, and generating positioning wing data for connecting the natural tooth close to the bone defect position and the titanium mesh according to the three-dimensional data of the titanium mesh and the 3D model data; and 4, step 4: determining a positioning hole for fixing the titanium mesh on the jaw bone by the three-dimensional data of the titanium mesh; and 5: and (5) titanium mesh printing. Due to the arrangement of the positioning wings, the position matching between the titanium mesh and the adjacent natural teeth is realized, and when the titanium mesh is installed, the installation position of the titanium mesh can be positioned according to the positioning wings, so that the titanium mesh can be accurately fixed at a preset position.

Description

Method for manufacturing titanium mesh for alveolar bone defect
Technical Field
The invention relates to the field of titanium mesh manufacturing, in particular to a method for manufacturing a titanium mesh for alveolar bone defect.
Background
Local large-area alveolar ridge bone defect reconstruction and bone regeneration are always difficult points for oral implant repair, and when the alveolar bone is absorbed in the horizontal direction and the vertical direction at the same time, three-dimensional reconstruction is more difficult. In 2001, Maiorana et al (1) applied a titanium mesh and a bone powder material (the ratio of autologous ilium to inorganic bovine bone is 1: 1) to perform bone amplification, and the titanium mesh is proved to be effective in human alveolar ridge bone mass amplification from clinical and histological levels for the first time. The study showed that: by using the titanium mesh as a barrier for bone regeneration, the bone increment can reach 10mm in the vertical direction and the horizontal direction, which is far larger than that under the condition of not using the titanium mesh as a support, and the long-term bone absorption capacity is smaller than that of the case without using the titanium mesh (2-4).
Nowadays, titanium mesh is often used in cases where bone defect is severe and rigid support is required to achieve large area bone regeneration due to its good mechanical properties. In the clinical bone grafting operation process, the finished titanium mesh needs to be trimmed and shaped so as to form the appearance of the joint bone defect, and meanwhile, the titanium mesh is also ensured to be overlapped with the periphery and the bone in partial area so as to fix the membrane nail. In clinical application, doctors are confronted with various bone defects, and not all finished titanium meshes can completely cover the range of the bone defects after trimming, so that the operation effect is poor. (5) A titanium mesh that does not fit well against the bone wall will cause the wound to split, resulting in exposure of the titanium mesh. Partial clinical case studies have shown that the incidence of titanium mesh exposure is as high as 50%. On the other hand, in the face of irregular bone defect appearance, the trimming of the titanium mesh is very complicated, the operation difficulty is high, long intraoperative time (6) is occupied, and the influence on the operative region of a patient and the postoperative recovery are both adversely affected.
Currently, digital-Aided Design (CAD) has been used to reconstruct the bone defect morphology from CBCT data of a patient and to Design the bone graft and the shape of the corresponding support material based on the bone defect range. Digital-to-analog Manufacturing (CAM) can be implemented by metal printing. Research shows that the personalized titanium net manufactured by metal printing is stable in form, sufficient in strength, effective and safe in clinical use (6-8). The only problem is that the contact area of the titanium mesh and the basal bone is limited, the positioning error is large, the inosculation degree between the titanium mesh and the dentition or the basal bone is deviated, and the proper fixing position is difficult to determine in the operation. Therefore, the positioning accuracy of the titanium net is improved, the positioning error of the titanium net is avoided, and the convenience of using the titanium net can be further improved. The CAD/CAM 3D printing personalized medical osteogenesis titanium net which is researched and developed independently is not available in China. There is also no titanium mesh aid with precise positioning capability.
Disclosure of Invention
Aiming at the defects in the prior art, the invention aims to provide a method for manufacturing a titanium mesh for alveolar bone defect, which can manufacture the titanium mesh which is accurately matched with the bone defect position.
In order to achieve the purpose, the invention provides the following technical scheme:
a method for manufacturing a titanium mesh for alveolar bone defect comprises the following steps:
step 1: generating 3D model data, acquiring dentition data and jaw data through oral scanning, and synthesizing the dentition and jaw 3D model data according to the dentition data and the jaw data;
step 2: establishing titanium mesh three-dimensional data according to the 3D model data, determining a bone defect structure according to the 3D model data, and generating titanium mesh three-dimensional data covering the bone defect structure according to the bone defect structure;
and step 3: generating a positioning wing, and generating positioning wing data for connecting the natural tooth close to the bone defect position and the titanium mesh according to the three-dimensional data of the titanium mesh and the 3D model data;
and 4, step 4: determining a titanium mesh positioning hole, and determining a positioning hole for fixing the titanium mesh on the jaw bone according to the three-dimensional data of the titanium mesh;
and 5: and (4) printing the titanium mesh, namely printing the titanium mesh with the positioning wings by using a 3D printing technology.
By adopting the technical scheme, the 3D model data is synthesized with the jaw bone data according to the dentition data, so that the titanium mesh three-dimensional data not only can be matched with the bone defect structure, but also can be matched with the dentition structure near the bone defect structure, and the titanium mesh manufactured according to the titanium mesh three-dimensional data can be more adaptive to the bone defect position. Due to the arrangement of the positioning wings, the position matching between the titanium mesh and the adjacent natural teeth is realized, and when the titanium mesh is installed, the installation position of the titanium mesh can be positioned according to the positioning wings, so that the titanium mesh can be accurately fixed at a preset position. According to the technical scheme, the titanium mesh which can be matched with the bone defect position can be manufactured, and the situation that the positioning is inaccurate in the installation process of the titanium mesh is prevented.
As a modification of the present invention, the step 1 comprises
Step 1-1: acquiring oral scan data, and scanning the oral cavity through an oral scanner to obtain the oral scan data with clear dentitions;
step 1-2: acquiring dentition data, and scanning the oral cavity by a CBCT (cone beam computed tomography) technology to obtain CT data with clear jaw bone structures;
step 1-3: and synthesizing 3D model data, and synthesizing the oral scan data and the CT data into 3D model data with clear dentition and jaw bone.
Through adopting above-mentioned technical scheme, because CT scanning can not the single clear dentition data and jaw data of scanning simultaneously, can realize deriving dentition data and jaw structural data respectively through oral scan appearance and CBCT scanning to synthesize two kinds of data, obtain the 3D model data that can clearly reflect dentition data and jaw data.
As a modification of the present invention, said step 2 comprises
Step 2-1: determining a post-operation structure of a bone defect position, simulating a jaw bone structure after a bone augmentation operation to determine an actual defect structure of the bone defect position, and generating a corresponding 3D working model;
step 2-2: filling the undercut of the 3D working model, simulating the titanium mesh installation process, filling the undercut part of the 3D working model, and correspondingly generating a 3D positioning model;
step 2-3: and generating titanium mesh three-dimensional data, and generating the titanium mesh three-dimensional data covering the actual defect structure according to the 3D positioning model.
By adopting the technical scheme, because the bone defect size after the femoral augmentation surgery is larger than the bone defect size obtained by jaw bone scanning, if the size of the titanium mesh is determined by the bone defect size obtained by simple scanning, the structure of the titanium mesh after being installed is unstable, and the post-operative structure of the bone defect position can realize accurate control of the bone defect position. The 3D working model inverted concave device is filled, so that the structure filling of the 3D model data is realized, and the mutual interference between the titanium mesh and the dentition or the jaw bone in the subsequent titanium mesh designing process is avoided.
As an improvement of the invention, the distance between the virtual titanium mesh boundary line corresponding to the titanium mesh three-dimensional data and the actual defect structure edge is not less than 3 mm.
As an improvement of the invention, the distance between the virtual titanium mesh boundary line corresponding to the titanium mesh three-dimensional data and the adjacent natural tooth is not less than 5 mm.
As a modification of the present invention, said step 3 comprises
Step 3-1: determining a support positioning line, and extending the alveolar bone crest corresponding to the titanium mesh three-dimensional data to the midpoint of the dentognathic face of the corresponding natural tooth along the peripheral surface of the 3D positioning model to generate the support positioning line;
step 3-2: generating a positioning surface, extending along the dentognathic face of the corresponding natural tooth by a support positioning line, and generating the positioning surface;
step 3-3: and generating positioning wing data, performing three-dimensional stretching on the positioning surface to generate a positioning plate, and extending the positioning plate to the part, close to the natural tooth, of the alveolar bone crest corresponding to the titanium mesh three-dimensional data along the support positioning line to generate the positioning wing data.
Through adopting above-mentioned technical scheme, because it extends along 3D location model global to prop up the support location line for prop up support location line and 3D location model laminating, because the locating surface is extended along the dentognathic face of natural tooth by propping up the support location line and is generated, make the dentognathic face of natural tooth of locating surface laminating completely, the dentognathic face of the natural tooth of locating wing laminating promptly, make when fixed titanium net, the laminating mode of locating wing and being close on between the natural tooth is only, and then the position of titanium net has been accurate.
As a refinement of the invention, the coverage rate of the positioning wing corresponding to the positioning wing data on the dentognathic face of the corresponding natural tooth is not less than 1/3.
As an improvement of the invention, the diameter of the part of the positioning wing, which is adjacent to the titanium mesh and corresponds to the positioning wing data, is not less than 1.5 mm.
In summary, the invention has the following advantages:
1. the personalized titanium net realizes the personalized design of different defect conditions and improves the operation accuracy and the treatment effect.
The preoperative design and manufacture reduce the intraoperative operation time and the operation difficulty;
2. the natural tooth positioning improves the positioning precision of the titanium mesh and the membrane nail and further improves the predictability of the operation;
3. high-precision 3D printing, determining the size of the titanium mesh according to the size of bone defects, reducing the occupied space of the titanium mesh to the maximum extent, reducing the operation difficulty and the probability of postoperative complications, and improving the success rate of the operation.
Drawings
FIG. 1 is a flow chart of a method of making a titanium mesh for alveolar bone defects;
FIG. 2 is a schematic structural diagram of a titanium mesh and a positioning model installed in 3D.
Reference numerals: 1. positioning the wing; 2. a titanium mesh; 3. the positioning line is supported.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings. In which like parts are designated by like reference numerals. It should be noted that the terms "front," "back," "left," "right," "upper" and "lower" used in the following description refer to directions in the drawings, and the terms "bottom" and "top," "inner" and "outer" refer to directions toward and away from, respectively, the geometric center of a particular component.
A method for manufacturing a titanium mesh for alveolar bone defect, as shown in fig. 1 and 2, comprising the steps of:
step 1: 3D model data is generated.
Step 1-1: and acquiring oral scan data, and scanning the oral cavity through an oral scanner to obtain the oral scan data with clear dentitions.
Step 1-2: and acquiring dentition data, and scanning the oral cavity by a CBCT technology to obtain CT data with clear jaw bone structure.
Step 1-3: and synthesizing 3D model data, and synthesizing the oral scan data and the CT data into 3D model data with clear dentition and jaw bone.
When the mouth scan data and the CT data are synthesized, firstly, the mouth scan data and the CT data are aligned through the mimics research software, so that the spatial positions of data models in the mouth scan data and the CT data are the same, and then, the data models of the mouth scan data and the CT data are synthesized through the geographic software, so that 3D model data capable of clearly representing dentition data and jaw data are generated.
Step 2: and establishing titanium mesh three-dimensional data according to the 3D model data.
Step 2-1: determining the postoperative structure of the bone defect position, simulating the jaw bone structure after bone augmentation surgery through freeform plus software to determine the actual defect structure of the bone defect position, and generating a corresponding 3D working model.
Step 2-2: filling the undercut of the 3D working model, simulating the installation process of the titanium mesh 2, filling the undercut part of the 3D working model through 3shape software, and correspondingly generating the 3D positioning model.
Step 2-3: and generating three-dimensional data of the titanium mesh 2, and generating the three-dimensional data of the titanium mesh 2 covering the actual defect structure according to the 3D positioning model.
Wherein, filling the inverted concavity of the 3D working model comprises filling the inverted concavity of the dentition and the inverted concavity of the jaw close to the bone defect position. In order to ensure that the titanium mesh 2 can completely cover the bone defect position and reserve a fixed position for fixing the titanium mesh 2, the distance between the boundary line of the virtual titanium mesh 2 corresponding to the three-dimensional data of the titanium mesh and the edge of the actual defect structure is not less than 3mm, and the distance is preferably 3 mm; in order to prevent the position between the titanium mesh 2 and the adjacent natural tooth from interfering with each other, the distance between the boundary line of the virtual titanium mesh 2 corresponding to the three-dimensional data of the titanium mesh 2 and the adjacent natural tooth is not less than 5mm, and preferably 5 mm.
And step 3: the positioning wing 1 is produced.
Step 3-1: and determining a support positioning line 3, and extending the part, close to the natural tooth, of the crest of the alveolar bone corresponding to the three-dimensional data of the titanium mesh to the midpoint of the dentognathic face of the corresponding natural tooth along the peripheral surface of the 3D positioning model to generate the support positioning line 3.
Step 3-2: and generating a positioning face, wherein the support positioning line 3 extends along the dentognathic face of the corresponding natural tooth to generate the positioning face.
Step 3-3: and generating positioning wing 1 data, performing three-dimensional stretching on the positioning surface to generate a positioning plate, extending the positioning plate to the part, close to the natural tooth, of the crest of the alveolar bone corresponding to the titanium mesh three-dimensional data along the support positioning line 3, and generating the positioning wing 1 data.
Wherein, the coverage rate of the positioning wing 1 corresponding to the positioning wing 1 data to the dentognathic face of the corresponding natural tooth is not less than 1/3.
And 4, step 4: and determining the positioning holes of the titanium mesh 2. And densely punching the titanium mesh 2 corresponding to the three-dimensional data of the titanium mesh by using 3D software, arranging positioning holes at the edge position where the titanium mesh 2 is attached to the jaw bone, and arranging at least two positioning holes at the two sides of the cheek and tongue of the jaw bone corresponding to the titanium mesh 2. The 3D software is preferably magics software.
And 5: and (3) printing the titanium mesh 2, wherein the titanium mesh 2 with the positioning wings 1 is printed by using a 3D printing technology.
In summary, due to the design of the positioning wing 1, after the titanium mesh 2 is successfully printed, the positioning wing 1 can be closely attached to the dentognathic face of the natural tooth near the bone defect position to position the titanium mesh 2. The titanium mesh 2 is then fixed to the jaw bone by means of membrane nails passing through the pilot holes. After the operation is completed, the positioning wing 1 is cut off, so that the positioning and installation of the titanium mesh 2 are completed.
Furthermore, in order to ensure the connection between the positioning wing 1 and the titanium net 2 and to ensure that the positioning wing 1 is not easy to deform, the diameter of the part, close to the titanium net 2, of the positioning wing 1 corresponding to the data of the positioning wing 1 is not less than 1.5 mm.
The present embodiment is only for explaining the present invention, and it is not limited to the present invention, and those skilled in the art can make modifications of the present embodiment without inventive contribution as needed after reading the present specification, but all of them are protected by patent law within the scope of the claims of the present invention.

Claims (8)

1. A method for manufacturing a titanium mesh for alveolar bone defect is characterized by comprising the following steps:
step 1: generating 3D model data, acquiring dentition data and jaw data through oral scanning, and synthesizing the dentition and jaw 3D model data according to the dentition data and the jaw data;
step 2: establishing three-dimensional data of the titanium mesh (2) according to the 3D model data, determining a bone defect structure according to the 3D model data, and generating three-dimensional data of the titanium mesh (2) covering the bone defect structure according to the bone defect structure;
and step 3: generating a positioning wing (1) for positioning the installation position of the titanium mesh (2), and generating data of the positioning wing (1) for connecting the natural tooth close to the bone defect position with the titanium mesh (2) according to the three-dimensional data of the titanium mesh (2) and the 3D model data;
and 4, step 4: determining a positioning hole of the titanium mesh (2), and determining a positioning hole for fixing the titanium mesh (2) on the jaw bone according to the three-dimensional data of the titanium mesh (2);
and 5: printing a titanium net (2), namely printing the titanium net (2) with the positioning wings (1) by using a 3D printing technology;
the positioning wings can be cut off after operation, so that the positioning and installation of the titanium mesh are realized.
2. The method for manufacturing a titanium mesh for alveolar bone defect according to claim 1, wherein: the step 1 comprises
Step 1-1: acquiring oral scan data, and scanning the oral cavity through an oral scanner to obtain the oral scan data with clear dentitions;
step 1-2: acquiring dentition data, and scanning the oral cavity by a CBCT (cone beam computed tomography) technology to obtain CT data with clear jaw bone structures;
step 1-3: and synthesizing 3D model data, and synthesizing the oral scan data and the CT data into 3D model data with clear dentition and jaw bone.
3. The method for manufacturing a titanium mesh for alveolar bone defect according to claim 1, wherein: the step 2 comprises
Step 2-1: determining a post-operation structure of a bone defect position, simulating a jaw bone structure after a bone augmentation operation to determine an actual defect structure of the bone defect position, and generating a corresponding 3D working model;
step 2-2: filling the inverted concave part of the 3D working model, simulating the installation process of the titanium mesh (2), filling the inverted concave part of the 3D working model, and correspondingly generating a 3D positioning model;
step 2-3: generating three-dimensional data of the titanium net (2), and generating the three-dimensional data of the titanium net (2) covering the actual defect structure according to the 3D positioning model.
4. The method for manufacturing a titanium mesh for alveolar bone defect according to claim 3, wherein: and the distance between the boundary line of the virtual titanium net (2) corresponding to the three-dimensional data of the titanium net (2) and the edge of the actual defect structure is not less than 3 mm.
5. The method for manufacturing a titanium mesh for alveolar bone defect according to claim 3, wherein: the distance between the boundary line of the virtual titanium mesh (2) corresponding to the three-dimensional data of the titanium mesh (2) and the adjacent natural tooth is not less than 5 mm.
6. The method for manufacturing a titanium mesh for alveolar bone defect according to claim 3, wherein: said step 3 comprises
Step 3-1: determining a support positioning line (3), extending the alveolar bone crest corresponding to the three-dimensional data of the titanium mesh (2) to the midpoint of the dentognathic face of the corresponding natural tooth along the peripheral surface of the 3D positioning model to generate the support positioning line (3);
step 3-2: generating a positioning face, extending along the dentognathic face of the corresponding natural tooth by a support positioning line (3) to generate the positioning face;
step 3-3: and generating data of the positioning wings (1), performing three-dimensional stretching on the positioning surface to generate a positioning plate, extending the positioning plate to the part, close to the natural teeth, of the crest of the alveolar bone corresponding to the three-dimensional data of the titanium mesh (2) along the support positioning line (3), and generating data of the positioning wings (1).
7. The method for manufacturing a titanium mesh for alveolar bone defect according to claim 6, wherein: and the coverage rate of the positioning wing (1) corresponding to the data of the positioning wing (1) to the dentognathic face of the corresponding natural tooth is not less than 1/3.
8. The method for manufacturing a titanium mesh for alveolar bone defect according to claim 7, wherein: the diameter of the part, close to the titanium mesh (2), of the positioning wing (1) corresponding to the data of the positioning wing (1) is not less than 1.5 mm.
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CN111870400B (en) * 2020-07-10 2021-03-26 四川大学 Alveolar bone augmentation surgery personalized titanium mesh guiding and positioning device and manufacturing method
CN112998886B (en) * 2021-02-08 2022-07-22 姜雨汐 Self-fixing bracket for natural tooth root peripheral alveolar bone increment and manufacturing method thereof
CN113520638B (en) * 2021-06-18 2022-06-28 佳木斯大学 Design and manufacturing method of titanium mesh for alveolar bone increment
CN115429468B (en) * 2022-10-09 2023-07-28 徐州市口腔医院 Individualized bone meal molding device for oral implant
CN115737212B (en) * 2022-11-12 2023-07-07 迪迈仕(北京)科技有限责任公司 Design method of personalized titanium mesh capable of realizing synchronous implantation with implant

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CN107174361A (en) * 2017-06-12 2017-09-19 四川大学 Guide plate of stretching alveolar bone skeletonization and preparation method thereof and application method
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