CN108991497A - A kind of preparation method of the nutrient buccal tablet with prevention memory loss function - Google Patents

A kind of preparation method of the nutrient buccal tablet with prevention memory loss function Download PDF

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Publication number
CN108991497A
CN108991497A CN201810639707.5A CN201810639707A CN108991497A CN 108991497 A CN108991497 A CN 108991497A CN 201810639707 A CN201810639707 A CN 201810639707A CN 108991497 A CN108991497 A CN 108991497A
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grams
preparation
buccal tablet
completion
nutrient buccal
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CN201810639707.5A
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罗国球
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Individual
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23PSHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00Shaping or working of foodstuffs characterised by the products
    • A23P10/20Agglomerating; Granulating; Tabletting
    • A23P10/28Tabletting; Making food bars by compression of a dry powdered mixture
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention discloses a kind of preparation methods of nutrient buccal tablet with prevention memory loss function, comprising the following steps: the raw material chosen is prepared by a. first;B. after carry out preparation preparation after the completion of step a again;C. after the completion of step b, the stirring fusion of raw material, preparation is carried out again after the completion;D. after the completion of step c, then the preparation of nutrient buccal tablet is carried out;E. after the completion of step d, finally nutrient buccal tablet is collected, in the preparation process for carrying out nutrient buccal tablet, it can be by adding Chinese herbal medicine, utilize the pharmacological of Chinese herbal medicine, to cooperate preparation to carry out using increasing environmental protection characteristic on the basis of ensure that curative effect, it is easily absorbed by the body, side effect is smaller, convenient for promoting, can control platform by adding in one, to carry out the finished product after tabletting the detection of sense organ, net content, moisture content, impurity, increase safety, it is ensured that the safety of nutrient buccal tablet is convenient for promoting.

Description

A kind of preparation method of the nutrient buccal tablet with prevention memory loss function
Technical field
It is specially a kind of with prevention memory loss function the present invention relates to nutrient buccal tablet preparation method technical field The preparation method of nutrient buccal tablet.
Background technique
Lozenge refers to contained in the compressed tablets being slowly dissolved in oral cavity, can to oral cavity and it is pharyngeal generate lasting drug effect, be used for office Anti-inflammatory, the disinfection in portion etc., buccal medicine or pill treatment pharyngitis have the advantage that 1. act directly on it is pharyngeal.With it is antibacterial, The effects of sterilization, anti-inflammatory, detumescence, desaturation thick secretions, convergence, stimulation mucosal secretions.2. due to slowly containing changing, making drug It the long period can rest on pharyngeal, persistently play drug effect.3. feeling quick for alleviating the discomforts such as dry throat, pharyngalgia.4. having The effects of antibacterial, sterilization, anti-inflammatory, detumescence, desaturation thick secretions, convergence, stimulation mucosal secretions.
Currently, the nutrient buccal tablet of prevention memory loss function, can cooperate the middle-aged and the old to be administered orally, but in reality Border, for the speed and prices of raw materials control for guaranteeing production, all generally uses in use, in the preparation process to nutrient buccal tablet Preparation is directly merged, this just produces certain harm to human body, is not easy to be used for a long time, and can generate the pair of part Effect, secondly because lozenge belongs to the tablet of mouth containing, when can be generated to the throat of people direct there are in the case where quality problems It influences, damage is larger, and influences whether the sale in later period, these are all physical presence and urgent problem.
Summary of the invention
The technical problem to be solved by the present invention is to overcome the defects of the prior art, provide a kind of with prevention memory loss The preparation method of the nutrient buccal tablet of function can utilize medium-height grass by adding Chinese herbal medicine in the preparation process for carrying out nutrient buccal tablet The pharmacological of medicine, to cooperate preparation to carry out using on the basis of ensure that curative effect, increasing environmental protection characteristic, be easy to by human body It absorbs, side effect is smaller, convenient for promoting, can control platform by adding in one, carries out sense organ, net to the finished product after tabletting The detection of content, moisture content, impurity, increases safety, it is ensured that the safety of nutrient buccal tablet is convenient for promoting.
To solve the above problems, the invention provides the following technical scheme: a kind of battalion with prevention memory loss function Support the preparation method of lozenge, comprising the following steps:
A. the raw material chosen is prepared first;
B. after carry out preparation preparation after the completion of step a again;
C. after the completion of step b, the stirring fusion of raw material, preparation is carried out again after the completion;
D. after the completion of step c, then the preparation of nutrient buccal tablet is carried out;
E. after the completion of step d, finally nutrient buccal tablet is collected.
As a kind of preferred embodiment of the invention, in the step a: 6 grams of raw material Radix Salviae Miltiorrhizae, 2 grams of Radix Notoginseng, Rhizoma Chuanxiong 9 Gram, 11 grams of pueraria lobata, 6 grams of safflower, 5 grams of Tong puncture vine, 7 grams of the root of fangji, 7 grams of caulis piperis futokadsurae, 3 grams of ilex pubescens, 4 grams of iron holly bark, gynostemma pentaphylla 2 Gram, carve 4 grams of leaf anise, 7 grams of rhizoma acori graminei, 3 grams of fructus alpiniae oxyphyllae, 9 grams of ginkgo leaf, 4 grams of panax ginseng fruit, 2 grams of Rhizoma Gastrodiae, 3 grams of broomrape, Wu's cornel 5 grams, 11 grams of Radix Paeoniae Alba, 4 grams of rhizoma anemarrhenae, 6 grams of American Ginseng.
As a kind of preferred embodiment of the invention, in the step b, preparation is Zinc-rich saccharomyces cerevisiae 2% -90%, richness Selenium yeast 0.001% -90%, lecithin 0.1% -10%, vitaminB10 .001% -10%, vitamin B20.001% -10%, vitamin B12 0.00002% -0.05%, vitamin C 0.1% -30%.
As a kind of preferred embodiment of the invention, in the step c, blender is vortex stirring mechanism, is merged Journey is 20min, and the rotation of motor is 2700r/min in the process, it is ensured that is distinguished after fusion without obvious color value, wherein temperature is 30 DEG C -50 DEG C, then stand 40min.
As a kind of preferred embodiment of the invention, the step d further includes preparation method, and step includes as follows;
S1, it pelletizes after being weighed by formula first, raw material is added one by one granulation by ingredient adding order, and control water Point content 5-8%, it is agglomerating with what is pinched, touching it is i.e. scattered subject to, it is uniform to produce satisfactory grain graininess;
It after S2, step S1, then is dried and is detected, chosen medicinal material dryer with coal and make fuel combustion, generate clean Net hot-air is as dried medium, to absorb the moisture in Chinese medicine, exhausts the humid air for reaching certain moisture, reciprocation cycle, The particle produced need to carry out being dried to moisture content lower than 5% hereinafter, and detecting moisture content and meeting relevant criterion requirement, side in time Next procedure can be transferred to;
After S3, step S2, then tabletting is carried out, tabletting uses Highspeedrotarytabletpress, and the axle center of mold is with turntable The linear velocity of rotation is not less than 60m/min, and the particle after whole grain need to carry out tabletting in time, with anti-moisture absorption and contaminated, particle stream Dynamic property is good, and piece shape is complete, and slice weight is uniform, every slice weight: 1.7g ± 0.0765g;
Platform is controlled after S4, step S3, in recycling to be classified the lozenge made, sense organ, net content, The undesirable and impure lozenge of moisture content is rejected, and packaged finished product need to be closed through sense organ, physics and chemistry, microorganism detection After lattice, warehouse for finished product and outbound sale can be entered.
Compared with prior art, beneficial effects of the present invention are as follows:
A kind of preparation method of the nutrient buccal tablet with prevention memory loss function of the present invention, is carrying out nutrient buccal tablet It, can be by adding Chinese herbal medicine, using the pharmacological of Chinese herbal medicine, to cooperate preparation to carry out using treating ensure that in preparation process On the basis of effect, environmental protection characteristic is increased, is easily absorbed by the body, side effect is smaller, secondly can be by adding one convenient for promoting A middle control platform carries out the detection of sense organ, net content, moisture content, impurity to the finished product after tabletting, increases safety Property, it is ensured that the safety of nutrient buccal tablet is convenient for promoting.
Specific embodiment
The present invention provides a kind of technical solution: a kind of preparation side of the nutrient buccal tablet with prevention memory loss function Method, comprising the following steps:
A. the raw material chosen is prepared first;
B. after carry out preparation preparation after the completion of step a again;
C. after the completion of step b, the stirring fusion of raw material, preparation is carried out again after the completion;
D. after the completion of step c, then the preparation of nutrient buccal tablet is carried out;
E. after the completion of step d, finally nutrient buccal tablet is collected.
In the step a: 6 grams of raw material Radix Salviae Miltiorrhizae, 2 grams of Radix Notoginseng, 9 grams of Rhizoma Chuanxiong, 11 grams of pueraria lobata, 6 grams of safflower, 5 grams of Tong puncture vine, 7 grams of the root of fangji, 3 grams of ilex pubescens, 4 grams of iron holly bark, 2 grams of gynostemma pentaphylla, carves 4 grams of leaf anise, 7 grams of rhizoma acori graminei, fructus alpiniae oxyphyllae 3 at 7 grams of caulis piperis futokadsurae Gram, 9 grams of ginkgo leaf, 4 grams of panax ginseng fruit, 2 grams of Rhizoma Gastrodiae, 3 grams of broomrape, 5 grams of Wu's cornel, 11 grams of Radix Paeoniae Alba, 4 grams of rhizoma anemarrhenae, 6 grams of American Ginseng.
In the step b, preparation is Zinc-rich saccharomyces cerevisiae 2% -90%, Se-enriched yeast 0.001% -90%, lecithin 0.1% -10%, vitaminB10 .001% -10%, vitamin B2 0.001% -10%, vitamin B12 0.00002% - 0.05%, vitamin C 0.1% -30%.
In the step c, blender is vortex stirring mechanism, and fusion process 20min, the rotation of motor in the process is 2700r/min, it is ensured that distinguished after fusion without obvious color value, wherein temperature is 30 DEG C -50 DEG C, then stands 40min.
The step d further includes preparation method, and step includes as follows;
S1, it pelletizes after being weighed by formula first, raw material is added one by one granulation by ingredient adding order, and control water Point content 5-8%, it is agglomerating with what is pinched, touching it is i.e. scattered subject to, it is uniform to produce satisfactory grain graininess;
It after S2, step S1, then is dried and is detected, chosen medicinal material dryer with coal and make fuel combustion, generate clean Net hot-air is as dried medium, to absorb the moisture in Chinese medicine, exhausts the humid air for reaching certain moisture, reciprocation cycle, The particle produced need to carry out being dried to moisture content lower than 5% hereinafter, and detecting moisture content and meeting relevant criterion requirement, side in time Next procedure can be transferred to;
After S3, step S2, then tabletting is carried out, tabletting uses Highspeedrotarytabletpress, and the axle center of mold is with turntable The linear velocity of rotation is not less than 60m/min, and the particle after whole grain need to carry out tabletting in time, with anti-moisture absorption and contaminated, particle stream Dynamic property is good, and piece shape is complete, and slice weight is uniform, every slice weight: 1.7g ± 0.0765g;
Platform is controlled after S4, step S3, in recycling to be classified the lozenge made, sense organ, net content, The undesirable and impure lozenge of moisture content is rejected, and packaged finished product need to be closed through sense organ, physics and chemistry, microorganism detection After lattice, warehouse for finished product and outbound sale can be entered.
In a kind of preparation method of nutrient buccal tablet with prevention memory loss function, nutrient buccal tablet is being carried out first Preparation process in, can be by adding Chinese herbal medicine, using the pharmacological of Chinese herbal medicine, to cooperate preparation to carry out using ensure that On the basis of curative effect, environmental protection characteristic is increased, is easily absorbed by the body, side effect is smaller, secondly can be by adding convenient for promoting Platform is controlled in one, the detection of sense organ, net content, moisture content, impurity is carried out to the finished product after tabletting, increases safety Property, it is ensured that the safety of nutrient buccal tablet is convenient for promoting.
Now made a kind of nutrient buccal tablet with prevention memory loss function and certain market are common through the invention Lozenge carries out Experimental Comparison, and test process is as follows;
1, cooperate bloodletting instrument, first draw blood, then the blood for taking lozenge half an hour after is extracted, examine respectively It tests.
2, compatibility test basin is placed in 1L distilled water, carries out throwing stirring to lozenge, stands after five minutes, remaining to basin bottom Particle is collected weighing, calculates melt water according to percentages.
3, during the preparation process, from starting subject to pan feeding, cooperation time set carries out timing to embodiment, is subject to discharging, Timing pause TP is carried out, to determine the speed of preparation.
4, embodiment uses Indirect Determination, is measured with high accuracy, highly sensitive method various in high purity material Then impurity content subtracts purity of the percentage as the high purity material of surveyed total impurities from test substance.
Test data is as follows:
Absorptivity/% Melt water/M2 Rate of extraction/H Extract purity/%
Embodiment 1 68 3.2 2.3 ≥74
Reinspection 69 3.4 2.2 ≥74.2
Comparative example 1 89 7.2 1.5 ≥92
It is a kind of made by the present invention that there is absorption with the nutrient buccal tablet for preventing memory loss function through Experimental comparison Rate is high, rate of extraction is fast and extracts purity and degree of safety, relatively there is great raising in the past.
The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention, for this field skill For art personnel, it is clear that invention is not limited to the details of the above exemplary embodiments, and without departing substantially from spirit of the invention or In the case where essential characteristic, the present invention can be realized in other specific forms.Therefore, in all respects, should all incite somebody to action Embodiment regards exemplary as, and is non-limiting, the scope of the present invention by appended claims rather than on state Bright restriction, it is intended that including all changes that fall within the meaning and scope of the equivalent elements of the claims in the present invention It is interior.Any label in claim should not be construed as limiting the claims involved.
The foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention, although referring to aforementioned reality Applying example, invention is explained in detail, for those skilled in the art, still can be to aforementioned each implementation Technical solution documented by example is modified or equivalent replacement of some of the technical features.It is all in essence of the invention Within mind and principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.

Claims (5)

1. a kind of preparation method of the nutrient buccal tablet with prevention memory loss function, it is characterised in that: the following steps are included:
A. the raw material chosen is prepared first;
B. after carry out preparation preparation after the completion of step a again;
C. after the completion of step b, the stirring fusion of raw material, preparation is carried out again after the completion;
D. after the completion of step c, then the preparation of nutrient buccal tablet is carried out;
E. after the completion of step d, finally nutrient buccal tablet is collected.
2. a kind of preparation method of nutrient buccal tablet with prevention memory loss function according to claim 1, special Sign is: in the step a: 6 grams of raw material Radix Salviae Miltiorrhizae, 9 grams of Rhizoma Chuanxiong, 11 grams of pueraria lobata, 6 grams of safflower, 5 grams of Tong puncture vine, is prevented 2 grams of Radix Notoginseng Oneself 7 grams, 7 grams of caulis piperis futokadsurae, 3 grams of ilex pubescens, 4 grams of iron holly bark, 2 grams of gynostemma pentaphylla, carve 4 grams of leaf anise, 7 grams of rhizoma acori graminei, fructus alpiniae oxyphyllae 3 Gram, 9 grams of ginkgo leaf, 4 grams of panax ginseng fruit, 2 grams of Rhizoma Gastrodiae, 3 grams of broomrape, 5 grams of Wu's cornel, 11 grams of Radix Paeoniae Alba, 4 grams of rhizoma anemarrhenae, 6 grams of American Ginseng.
3. a kind of preparation method of nutrient buccal tablet with prevention memory loss function according to claim 1, special Sign is: in the step b, preparation is Zinc-rich saccharomyces cerevisiae 2% -90%, Se-enriched yeast 0.001% -90%, lecithin 0.1% -10%, vitaminB10 .001% -10%, vitamin B2 0.001% -10%, vitamin B12 0.00002% - 0.05%, vitamin C 0.1% -30%.
4. a kind of preparation method of nutrient buccal tablet with prevention memory loss function according to claim 1, special Sign is: in the step c, blender is vortex stirring mechanism, and fusion process 20min, the rotation of motor in the process is 2700r/min, it is ensured that distinguished after fusion without obvious color value, wherein temperature is 30 DEG C -50 DEG C, then stands 40min.
5. a kind of preparation method of nutrient buccal tablet with prevention memory loss function according to claim 1, special Sign is: the step d further includes preparation method, and step includes as follows;
S1, it pelletizes after being weighed by formula first, raw material is added one by one granulation by ingredient adding order, and control moisture and contain Measure 5-8%, it is agglomerating with what is pinched, touching it is i.e. scattered subject to, it is uniform to produce satisfactory grain graininess;
It after S2, step S1, then is dried and is detected, chosen medicinal material dryer with coal and make fuel combustion, generate cleaning Hot-air is as dried medium, to absorb the moisture in Chinese medicine, exhausts the humid air for reaching certain moisture, reciprocation cycle is produced Particle need to carry out being dried to moisture content in time lower than 5% hereinafter, and detect moisture content and meet relevant criterion requirement, can be transferred to Next procedure;
After S3, step S2, then tabletting is carried out, tabletting uses Highspeedrotarytabletpress, and the axle center of mold is rotated with turntable Linear velocity be not less than 60m/min, the particle after whole grain need to carry out tabletting in time, with anti-moisture absorption and contaminated, mobility of particle Good, piece shape is complete, and slice weight is uniform, every slice weight: 1.7g ± 0.0765g;
Platform is controlled after S4, step S3, in recycling to be classified to the lozenge made, sense organ, net content, moisture The undesirable and impure lozenge of content is rejected, and packaged finished product need to be qualified through sense organ, physics and chemistry, microorganism detection Afterwards, warehouse for finished product and outbound sale can be entered.
CN201810639707.5A 2018-06-20 2018-06-20 A kind of preparation method of the nutrient buccal tablet with prevention memory loss function Pending CN108991497A (en)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1857666A (en) * 2006-03-14 2006-11-08 王信锁 Chinese medicine preparation for treating senile dementia
US20080181937A1 (en) * 2007-01-29 2008-07-31 Majid Fotuhi Dosage regimen and medicament for guarding memory and brain health and for preventing or reducing risk of onset of dementia by administration of specific vitamins and supplements (memoguard)
CN101757573A (en) * 2010-01-19 2010-06-30 泰一和浦(北京)中医药研究院有限公司 Traditional Chinese medicine composition for treating memory loss and preparation method thereof
CN101766659A (en) * 2008-12-30 2010-07-07 安琪酵母股份有限公司 Preparation having function of improving memories and preparation method and application thereof
CN104606515A (en) * 2015-03-04 2015-05-13 苏州市天灵中药饮片有限公司 Traditional Chinese medicine composition for improving memory and preparation method thereof
CN105831751A (en) * 2016-04-18 2016-08-10 重庆三峡医药高等专科学校 Health-care traditional Chinese medicine composition with effects of tonifying qi and strengthening brain and preparation method and using method thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1857666A (en) * 2006-03-14 2006-11-08 王信锁 Chinese medicine preparation for treating senile dementia
US20080181937A1 (en) * 2007-01-29 2008-07-31 Majid Fotuhi Dosage regimen and medicament for guarding memory and brain health and for preventing or reducing risk of onset of dementia by administration of specific vitamins and supplements (memoguard)
CN101766659A (en) * 2008-12-30 2010-07-07 安琪酵母股份有限公司 Preparation having function of improving memories and preparation method and application thereof
CN101757573A (en) * 2010-01-19 2010-06-30 泰一和浦(北京)中医药研究院有限公司 Traditional Chinese medicine composition for treating memory loss and preparation method thereof
CN104606515A (en) * 2015-03-04 2015-05-13 苏州市天灵中药饮片有限公司 Traditional Chinese medicine composition for improving memory and preparation method thereof
CN105831751A (en) * 2016-04-18 2016-08-10 重庆三峡医药高等专科学校 Health-care traditional Chinese medicine composition with effects of tonifying qi and strengthening brain and preparation method and using method thereof

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