CN108969091A - A kind of system of tumor treatment - Google Patents

A kind of system of tumor treatment Download PDF

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Publication number
CN108969091A
CN108969091A CN201810694966.8A CN201810694966A CN108969091A CN 108969091 A CN108969091 A CN 108969091A CN 201810694966 A CN201810694966 A CN 201810694966A CN 108969091 A CN108969091 A CN 108969091A
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China
Prior art keywords
subsystem
ablation
magnetic resonance
radio frequency
host computer
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CN201810694966.8A
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Chinese (zh)
Inventor
江河峻
周玉福
张晴
罗鹏辉
祁甫浪
甄博文
王长亮
智德波
徐莉
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Anhui Fuqing Medical Technology Co., Ltd.
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Anhui Ruijie Mdt Infotech Ltd
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Priority to CN201810694966.8A priority Critical patent/CN108969091A/en
Publication of CN108969091A publication Critical patent/CN108969091A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/103Treatment planning systems
    • A61N5/1039Treatment planning systems using functional images, e.g. PET or MRI
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048Monitoring, verifying, controlling systems and methods
    • A61N5/1049Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A61N2005/1055Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using magnetic resonance imaging [MRI]

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Otolaryngology (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Plasma & Fusion (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

The present invention provides a kind of system of tumor treatment, comprising: RF ablation subsystem, radiotherapy subsystem, magnetic resonance subsystem, optical guidance subsystem and host computer, RF ablation subsystem include radio frequency ablation needle.Magnetic resonance subsystem is connect with host computer, for generating the magnetic resonance image of corresponding patient.Host computer, for according to magnetic resonance image, the therapy target position of location Calculation tumor locus to determine radiotherapy target position according to the position of magnetic resonance image and radio frequency ablation needle.Optical guidance subsystem one end is connect with RF ablation subsystem, and one end is connect with host computer, for guiding radio frequency ablation needle to execute puncture, collects the position of radio frequency ablation needle.RF ablation subsystem is connect with host computer, and for being based on magnetic resonance image, under the guidance of optical guidance subsystem, control radio frequency ablation needle is punctured in therapy target position, carries out RF ablation.Radiotherapy subsystem is connect with host computer, for carrying out radiotherapy after completing RF ablation.

Description

A kind of system of tumor treatment
Technical field
The present invention relates to Medical Instruments technical field, in particular to a kind of system of tumor treatment.
Background technique
As the improvement of people's living standards, health problem becomes one of the problem of modern pays close attention to the most, in scientific skill When art is underdeveloped, to the mode that a series of illnesss such as solid tumor often take open surgery to treat, such therapeutic modality The problems such as there are treatment time is long, patient's recovery is slow and postoperative life quality is not high.With science and technology and Medical Imaging Technology Development, guided by magnetic resonance technology is also gradually widely used in medical domain, wherein the RF ablation knot of guided by magnetic resonance Close the major way that radiotherapy technology is increasingly becoming a series of symptoms such as treatment solid tumor.
The RF ablation combination radiotherapy technology of guided by magnetic resonance be therapeutic process is guided using magnetic resonance image and Monitoring, to guarantee the safety for the treatment of.But the RF ablation combination radiotherapy technology of existing guided by magnetic resonance is in different behaviour Make indoor progress, the operating time can be lengthened in this way, complexity is higher.Meanwhile the RF ablation combination radiotherapy skill of guided by magnetic resonance Art mainly utilizes image procossing, and the method for image segmentation tracks the position of determining radiotherapy, but the unconscious movement of patient can Can will lead to radion can not irradiated lesion position, must thus re-start image procossing, increase treatment time and drop The low accuracy of RF ablation.
Summary of the invention
In view of this, to solve in the prior art, guided by magnetic resonance is penetrated the present invention provides a kind of system of tumor treatment Frequency ablation combines radiotherapy technology over the course for the treatment of, there is a problem of that treatment time is too long low with RF ablation accuracy rate.
To achieve the above object, the embodiment of the present invention provides the following technical solutions:
The invention discloses a kind of system of tumor treatment, comprising:
RF ablation subsystem, radiotherapy subsystem, magnetic resonance subsystem, optical guidance subsystem and host computer, institute Stating RF ablation subsystem includes radio frequency ablation needle;
The magnetic resonance subsystem is connect with the host computer, for generating the magnetic resonance image of corresponding patient, and by institute It states magnetic resonance image and is sent to the host computer;
The host computer, for according to the magnetic resonance image, the therapeutic target of the tumor locus of patient described in location Calculation Point position, and radiotherapy target position is determined according to the position of the magnetic resonance image and radio frequency ablation needle;
Optical guidance subsystem one end is connect with the RF ablation subsystem, and one end is connect with the host computer, For guiding the radio frequency ablation needle to execute puncture, and the position of the radio frequency ablation needle is collected, by the radio frequency ablation needle Position is sent to the host computer;
The RF ablation subsystem is connect with the host computer, for being based on the magnetic resonance image, in the optics It under the guidance of navigation subsystem, controls the radio frequency ablation needle and is punctured in the therapy target position, execute RF ablation Treatment;
The radiotherapy subsystem is connect with the host computer, for the RF ablation subsystem complete described in penetrate Radiotherapy is carried out in the radiotherapy target position after frequency ablation.
Preferably, the host computer, the coordinate information for the radio frequency ablation needle for being also used to be transmitted according to navigation software, control The angle and direction for making the magnetic resonance subsystem scanning, makes the position of tumor locus and the radio frequency ablation needle be shown in institute It states in magnetic resonance image.
Preferably, the host computer is also used to control the ablation energy output valve of the radiofrequency ablation therapy, the ablation Energy output valve is the output current frequency value of the radiofrequency ablation therapy.
Preferably, the position according to the magnetic resonance image and radio frequency ablation needle determines the radiotherapy target position Host computer determines that the region of RF ablation area, the region are to be with the radio frequency ablation needle based on the magnetic resonance image The border circular areas of centre dot obtains the coordinate information of the radio frequency ablation needle, calculates the radiotherapy based on the coordinate information Target position, the radiotherapy target position are located at radiotherapy region, and the central point in the radiotherapy region is the radio frequency The coordinate of ablation needle.
Preferably, in the RF ablation subsystem for control the radio frequency ablation needle the therapy target position into The control equipment that row punctures is placed on outside therapeutic room.
Preferably, the magnetic resonance subsystem further includes monitoring device;
The monitoring device is monitored the radiofrequency ablation therapy process for being based on the magnetic resonance image.
Preferably, above-mentioned system, further includes:
Storage subsystem is connect with the host computer, is controlled for storing information that the host computer receives and tumour The various information generated during treating.
It is to utilize guided by magnetic resonance based on the above-mentioned technical proposal it is found that the invention discloses a kind of system of tumor treatment Radio-frequency ablation procedure combination radiotherapy treatment system, be allowed to perform the operation in an operating room, and using to RF ablation Needle carries out tracking and positioning to assist in the treatment of, and the radion that can be shortened treatment time and increase radio-frequency ablation procedure is radiated at lesion portion The accuracy of position.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this The embodiment of invention for those of ordinary skill in the art without creative efforts, can also basis The attached drawing of offer obtains other attached drawings.
Fig. 1 is a kind of structural schematic diagram of system of tumor treatment provided in an embodiment of the present invention;
Fig. 2 is a kind of structural schematic diagram of system of tumor treatment provided in an embodiment of the present invention;
Fig. 3 is a kind of structural schematic diagram of system of tumor treatment provided in an embodiment of the present invention.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
In this application, the terms "include", "comprise" or any other variant thereof is intended to cover non-exclusive inclusion, So that the process, method, article or equipment for including a series of elements not only includes those elements, but also including not having The other element being expressly recited, or further include for elements inherent to such a process, method, article, or device.Do not having There is the element limited in the case where more limiting by sentence "including a ...", it is not excluded that in the mistake including the element There is also other identical elements in journey, method, article or equipment.
With reference to Fig. 1, a kind of structural schematic diagram of system of tumor treatment provided in an embodiment of the present invention is shown, in the present invention In embodiment, the system of tumor treatment may include: magnetic resonance subsystem 101, host computer 102, optical guidance subsystem 103, RF ablation subsystem 104, radio frequency ablation needle 1041 and radiotherapy subsystem 105;
Magnetic resonance subsystem 101 is connect with host computer 102, for generating the magnetic resonance image of corresponding patient, by the magnetic Resonance image is sent to the host computer 102.
Host computer 102, for according to the magnetic resonance image, the therapy target of the tumor locus of patient described in location Calculation Position, and radiotherapy target position is determined according to the position of the magnetic resonance image and the radio frequency ablation needle 1041.
Optical guidance subsystem 103, one end are connect with the RF ablation subsystem 104, the other end and the host computer 102 connections, for guiding the radio frequency ablation needle 1041 to execute puncture, and collect the position of the radio frequency ablation needle 1041, will The position of the radio frequency ablation needle 1041 is sent to the host computer 102.
RF ablation subsystem 104 is connect with the host computer 102, for being based on the magnetic resonance image, in the light It under the guidance for learning navigation subsystem 103, controls the radio frequency ablation needle 1041 and is punctured in the therapy target position, execute Radiofrequency ablation therapy.
Radiotherapy subsystem 105 is connect with the host computer 102, for completing in the RF ablation subsystem 104 Radiotherapy is carried out in the radiotherapy target position after the radiofrequency ablation therapy.
Preferably, in conjunction with Fig. 1, host computer 102 described in the embodiment of the present invention are also used to according to the optical guidance subsystem The coordinate information of the radio frequency ablation needle 1041 of the navigation software transmission of system 103, controls the magnetic resonance subsystem 101 and scans Angle and direction, clearly indicate the position of tumor locus and the radio frequency ablation needle 1041 in the magnetic resonance image On, it is convenient to be monitored in puncture and ablation.
Preferably, in conjunction with Fig. 1, host computer 102 described in the embodiment of the present invention are also used to control the radiofrequency ablation therapy Ablation energy output valve, the ablation energy output valve be the radiofrequency ablation therapy output current frequency value.
Wherein, radio frequency refers to power frequency of the frequency between 300KHz~300GHz, and the effect in face of organism is main It is fuel factor, when the power frequency of radio frequency reaches certain value, i.e., power frequency is greater than 100kHz, because of the quick variation of electromagnetic field It moves intracellular positive and negative ion quickly, the hydrone of intraor extracellular can be caused to evaporate rapidly so that cell aseptic necrosis, To achieve the purpose that treatment.
Preferably, in conjunction with Fig. 1, host computer 102 described in the embodiment of the present invention are also used to true based on the magnetic resonance image Determine the region of RF ablation area, the region is the border circular areas with the radio frequency ablation needle 1041 for center dot.It obtains The coordinate information of the radio frequency ablation needle 1041 calculates the radiotherapy target position and radiotherapy based on the coordinate information Dosage.The radiotherapy target position is located at radiotherapy region, and the central point in the radiotherapy region is the RF ablation The dosage of the coordinate of needle 1041, the radiotherapy can be adjusted as the case may be.
Preferably, in conjunction with Fig. 1, for controlling the radio frequency in RF ablation subsystem described in the embodiment of the present invention 104 Ablation needle 1041 is placed on outside therapeutic room in the control equipment that the therapy target position is punctured.
Based on embodiments of the present invention Fig. 1 provide subsystems function, using following procedure (1) to (5) into Row for example:
(1) the RF ablation subsystem 104 is under the guidance of optical guidance subsystem 103, in conjunction with magnetic resonance subsystem 101 magnetic resonance image provided puncture the radio frequency ablation needle 1041 to tumor locus.
(2) ablation energy of RF ablation subsystem 104 described in the ablation control software control using the host computer 102 Output, and ablation procedure is monitored using the magnetic resonance image, it should be noted that the magnetic resonance subsystem 101 In the corresponding magnetic resonance image of scanning device real time scan patient, and the host computer 102 is sent to, to the ablation procedure It is monitored in real time.
(3) after the completion of the ablation, the ablation output of the RF ablation subsystem 104 is closed, instrument and institute are disconnected The connection of radio frequency ablation needle 1041 is stated, but the radio frequency ablation needle 1041 is still inserted at the tumor focus, is fixed using bandage On the skin of the patient.
(4) host computer 102 continues to scan on the magnetic resonance image, irises out the region of ablation area manually, needs Bright, the ablation areas is a border circular areas centered on 1041 needle point of radio frequency ablation needle, with the radio frequency The needle point coordinate of ablation needle 1041 is the center of radiotherapy, using the radius planned manually as the radius of the radiotherapy.
(5) radiotherapy for opening the host computer 102 guides software, obtains the radio frequency ablation needle that navigation software obtains 1041 coordinate information is calculated the position of optimal radiotherapy and the dosage of radiotherapy based on the coordinate information, needed Illustrate, the dosage of the radiotherapy can be adjusted according to the actual situation.
It should be noted that being breathed during implementing the above process (1) to (5) since the patient exists Movement, the tumour may have offset, but since the position of the radio frequency ablation needle 1041 also can be according to the offset of breathing And deviate, it can guarantee the radio frequency ablation needle 1041 always in the center of the tumour.Meanwhile in the process of radiotherapy In, it is also necessary to according to the tip position of the radio frequency ablation needle 1041 of acquisition to the direction of radiotherapy and radiotherapy away from From being adjusted, to guarantee that all radions can be radiated at the tumor locus.
In the embodiment of the present invention, by utilizing magnetic resonance subsystem, host computer, optical guidance subsystem, RF ablation System and radiotherapy subsystem quickly can accurately complete the therapeutic process of radio-frequency ablation procedure and radiotherapy, shorten treatment Process, and the radion that can also effectively improve radio-frequency ablation procedure and radiotherapy is radiated at the accuracy of lesions position.
Preferably, in conjunction with Fig. 1, with reference to Fig. 2, in a kind of system of tumor treatment described in the embodiment of the present invention, magnetic resonance Subsystem 101 includes: monitoring device 1011;
Monitoring device 1011 is monitored the radiofrequency ablation therapy process for being based on the magnetic resonance image.
It is corresponding with a kind of system of tumor treatment that aforementioned present invention provides, in conjunction with Fig. 2, with reference to Fig. 3, the embodiment of the present invention A kind of preferred embodiment of system of tumor treatment is additionally provided, in embodiments of the present invention, which may include: storage subsystem System 106;
Storage subsystem 106 is connect with the host computer 102, for store the information that the host computer 102 receives with And the various information generated in tumor therapeutic procedure.
It should be noted that the information that the storage subsystem 106 stores includes: magnetic resonance image, radio frequency ablation needle 1041 location information, ablation energy output information, therapy target location information, radiotherapy location information and radiotherapy Dosage information etc..Wherein, above- mentioned information are a portion information that the storage subsystem 106 needs to store, remaining The information for needing to store just does not illustrate all.
All the embodiments in this specification are described in a progressive manner, same and similar portion between each embodiment Dividing may refer to each other, and each embodiment focuses on the differences from other embodiments.Especially for system or For system embodiment, since it is substantially similar to the method embodiment, so describing fairly simple, related place is referring to method The part of embodiment illustrates.System and system embodiment described above is only schematical, wherein the conduct The unit of separate part description may or may not be physically separated, component shown as a unit can be or Person may not be physical unit, it can and it is in one place, or may be distributed over multiple network units.It can root According to actual need that some or all of the modules therein is selected to achieve the purpose of the solution of this embodiment.Ordinary skill Personnel can understand and implement without creative efforts.
Professional further appreciates that, unit described in conjunction with the examples disclosed in the embodiments of the present disclosure And algorithm steps, can be realized with electronic hardware, computer software, or a combination of the two, in order to clearly demonstrate hardware and The interchangeability of software generally describes each exemplary composition and step according to function in the above description.These Function is implemented in hardware or software actually, the specific application and design constraint depending on technical solution.Profession Technical staff can use different methods to achieve the described function each specific application, but this realization is not answered Think beyond the scope of this invention.
The foregoing description of the disclosed embodiments enables those skilled in the art to implement or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, as defined herein General Principle can be realized in other embodiments without departing from the spirit or scope of the present invention.Therefore, of the invention It is not intended to be limited to the embodiments shown herein, and is to fit to and the principles and novel features disclosed herein phase one The widest scope of cause.

Claims (7)

1. a kind of system of tumor treatment characterized by comprising
RF ablation subsystem, radiotherapy subsystem, magnetic resonance subsystem, optical guidance subsystem and host computer, it is described to penetrate Frequency ablation subsystem includes radio frequency ablation needle;
The magnetic resonance subsystem is connect with the host computer, for generating the magnetic resonance image of corresponding patient, and by the magnetic Resonance image is sent to the host computer;
The host computer, for according to the magnetic resonance image, the therapeutic target point of the tumor locus of patient described in location Calculation It sets, and radiotherapy target position is determined according to the position of the magnetic resonance image and radio frequency ablation needle;
Optical guidance subsystem one end is connect with the RF ablation subsystem, and one end is connect with the host computer, is used for It guides the radio frequency ablation needle to execute puncture, and collects the position of the radio frequency ablation needle, by the position of the radio frequency ablation needle It is sent to the host computer;
The RF ablation subsystem is connect with the host computer, for being based on the magnetic resonance image, in the optical guidance It under the guidance of subsystem, controls the radio frequency ablation needle and is punctured in the therapy target position, execute radiofrequency ablation therapy;
The radiotherapy subsystem is connect with the host computer, is disappeared for completing the radio frequency in the RF ablation subsystem Melt and carries out radiotherapy in the radiotherapy target position after treating.
2. system according to claim 1, which is characterized in that the host computer is also used to be transmitted according to navigation software The coordinate information of the radio frequency ablation needle controls the angle and direction of magnetic resonance subsystem scanning, make tumor locus and The position of the radio frequency ablation needle is shown in the magnetic resonance image.
3. system according to claim 1, which is characterized in that
The host computer is also used to control the ablation energy output valve of the radiofrequency ablation therapy, the ablation energy output valve For the output current frequency value of the radiofrequency ablation therapy.
4. system according to claim 1, which is characterized in that
The position according to the magnetic resonance image and radio frequency ablation needle determines the host computer of the radiotherapy target position, is based on The magnetic resonance image determines that the region of RF ablation area, the region are using the radio frequency ablation needle as the circle of center dot Shape region obtains the coordinate information of the radio frequency ablation needle, calculates the radiotherapy target position based on the coordinate information, described Radiotherapy target position is located at radiotherapy region, and the central point in the radiotherapy region is the coordinate of the radio frequency ablation needle.
5. system according to claim 1, which is characterized in that
For controlling the control that the radio frequency ablation needle is punctured in the therapy target position in the RF ablation subsystem Control equipment is placed on outside therapeutic room.
6. system according to claim 1, which is characterized in that the magnetic resonance subsystem further includes monitoring device;
The monitoring device is monitored the radiofrequency ablation therapy process for being based on the magnetic resonance image.
7. system as claimed in any of claims 1 to 6, which is characterized in that further include:
Storage subsystem is connect with the host computer, for storing the information and oncotherapy that the host computer receives The various information generated in journey.
CN201810694966.8A 2018-06-29 2018-06-29 A kind of system of tumor treatment Pending CN108969091A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109568814A (en) * 2018-12-27 2019-04-05 菅金波 A kind of system of tumor treatment of optical operation navigation

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CN106662626A (en) * 2014-05-09 2017-05-10 皇家飞利浦有限公司 A therapy system containing an mri module and means for determining the position of an rf coil
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EP2277553A1 (en) * 1999-02-02 2011-01-26 Senorx, Inc. Preparations for time-limited marking of biopsy sites
WO2001050156A1 (en) * 1999-12-30 2001-07-12 Transurgical, Inc. Interleaved operation of mri and electronic equipment
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109568814A (en) * 2018-12-27 2019-04-05 菅金波 A kind of system of tumor treatment of optical operation navigation
CN109568814B (en) * 2018-12-27 2022-03-18 菅金波 Tumor treatment system of optical operation navigation

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