CN108939171A - A kind of soluble condom and its production method with koro function - Google Patents
A kind of soluble condom and its production method with koro function Download PDFInfo
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- CN108939171A CN108939171A CN201810874354.7A CN201810874354A CN108939171A CN 108939171 A CN108939171 A CN 108939171A CN 201810874354 A CN201810874354 A CN 201810874354A CN 108939171 A CN108939171 A CN 108939171A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/048—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/005—Ingredients of undetermined constitution or reaction products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/202—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with halogen atoms, e.g. triclosan, povidone-iodine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/204—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
- A61L2300/206—Biguanides, e.g. chlorohexidine
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/204—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
- A61L2300/208—Quaternary ammonium compounds
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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Abstract
A kind of soluble condom and its production method with koro function, belongs to health care and family planning technology field, and bioactive molecule medical PVA is dissolved with glycerol and water, obtains the glycerite of polyvinyl alcohol;After disinfection sanitizer, spermatocide and the agent of nutrition koro are first mixed with propylene glycol and water, it is mixed again with the glycerite of polyvinyl alcohol, obtain mixed solution, by mixed solution with mould shape, solubility condom is made, it realizes in quick dissolution, while effectively practising contraception, can effectively treat common female sex organs infectious diseases, prevention spread of sexually transmitted diseases again, especially has the function of significant koro, life quality can be improved.
Description
Technical field
The invention belongs to health care and family planning technology fields, and in particular to the production technology of condom.
Background technique
It is investigated according to sex sociology, China leads to divorce because couple's sexual life is discord, and accounts for about the 28 of total the number of divorce
~59%;It is unsatisfied also up to 58% in the couple's sexual life investigation of non-divorced.Vaginal relaxation not only leads woman's forfeiture voluptus
Hyposexuality is caused, while also resulting in male's voluptus to reduce and lose interest to sexual life.With the increase at age, childbirth,
The influence of the factors such as sexual life, Estrin drop, genital tract are had in face of more pressure and are destroyed, profitable strain imbalance,
Vaginal environment deteriorates, so that various bacterial viruses are taken advantage of a weak point, to cause various reproductive diseases.The sum of sexual life
It is humorous, it is a key factor of conjugal relation sound development.With age or growing process causes vaginal wall thinning, elastic
It reduces, so as to cause occurring sexual desire reduction, pleasant sensation decline during couple's sexual life, causes companion discontented, serious initiation
Emotional risks.The mother of spontaneous labor, when fetus is given birth to by vagina, vagina all can obviously broaden, the baby head being generally born
The diameter in portion is there are about 10 centimetres, that is, vagina will be expanded to 10 centimetres (normal vagina diameter is 2.5 centimetres) when giving a birth.In addition, i.e.
Just the production of plane abdomen has been selected also not get rid of vaginal relaxation, mother can sufficiently extend in the muscle and ligament of pelvic cavity during labor, be
Birth canal preparation is carried out in the birth of baby, so even if carrying outCesarean esctionMother, vagina also has relaxation.Vaginal relaxation
It is a main cause for causing voluptus decline even to disappear in women;Vaginal relaxation is usually " the holding " of vagina to penis
Ability decline, carnal abuse are also just difficult to reach abundant, satisfied.Vaginal relaxation not only will affect the voluptus between man and wife,
Also it can cause some bacteria breeds, so that bacterium can enter in vivo faster, cause gynaecological imflammation, therefore some women just has
The demand and idea of koro.It is a kind of side for improving couple's sexual life quality and preventing gynecological infection that koro, which is exactly women,
Method.Now with the development of productivity, the progress of human knowledge, at abroad, due to the opening of attitude towards sex and to life quality
Expectation, koro has become the thing that people all know, and with the change of people's traditional concept, koro will cause mostly
The concern of number women.
The method of koro is by a variety of at present, koro operation, injection koro, koro stick and massage koro etc., and women is in order to reach
To vaginal contraction state and by a kind of external force tool.Since failure case occurs again and again, cicatrization causes organic damage
Wound, the effect of these koro methods are under suspicion in countries such as America and Europes at present, and safety is also disputable, so that many women are to contracting
Yin is hung back, and sight is more transferred on fanout free region koro product by some women.
Rubber condoms do not have koro function, and 70% male is unwilling using rubber condoms, because of rubber condoms
It can make one to generate unplessantness displeasure.Therefore, rubber condoms not can increase the disposition interest of people, can not ensure that the normality of people is raw
Bioplasm amount.
One is had developed in various deficiencies, the applicant present on contraception and the propagation of prevention of STD for rubber condoms
Kind, elastic approximate and application method identical soluble disinfecting condom identical as existing rubber condoms shape, and Shen
Please patent of invention 99114179.2, the main function of the sheath is 2-3 minutes to can dissolve in use, effective
While contraception, and the propagation that can effectively treat men and women's genitals bacterial infection disease, take precautions against venereal disease.But there is also it is some not
Foot, it is mainly significant not enough to the enhancing of sexual function, it especially do not have koro function, during the property of the loose person of vagina,
Men and women lack voluptus, it is thus impossible to meet the requirement that people improve life quality.
Summary of the invention
The object of the present invention is to provide a kind of soluble condoms with koro function.
The present invention includes bioactive molecule medical PVA, disinfection sanitizer, spermatocide, solvent, it is characterised in that also
4.711~13% nutrition koro agent including accounting for soluble condom gross mass.
The present invention is identical as existing soluble disinfecting condom shape, elastic approximate and application method is identical, due to
Wherein containing 4.711~13% nutrition koro agent, so this product can overcome the soluble sterilization of Patent No. 99114179.2
Disinfectant contraceptive covers above shortcomings, realizes in quick dissolution, effective contraception, can effectively treat common female sex organs again
While infectious diseases, prevention spread of sexually transmitted diseases, especially has the function of significant koro, improve men and women's disposition interest and sexual life matter
Amount.
For the present invention due to using bioactive molecule medical polyethylene alcoholic solution, the set being fabricated to enters vagina when in use
It can dissolve rapidly within interior 30 seconds, lose its original shape, release and include active constituent, be uniformly distributed with sexuality
It is absorbed in vagina mucosa and skin of penis mucous membrane and by vagina mucosa, so that vaginal fluid be made to increase, intravaginal is slightly generated heat,
Vagina elasticity and gripping force enhancing, and independence contraction occur, men and women is made to be easy to orgasm occur and obtain pleasant sensation, property is raw
Bioplasm amount significantly improves.
Above-mentioned koro process is blood circulation, metabolism and the nutrition by improving vaginal mucosal tissue, some activity
Ingredient also can be done directly on vagina smooth muscle myosin and actin, enhance the sliding property of thickness myofilament, be overlapped model
Enclose increasing;Increase female private part glandular secretion and nervus pudendus excitability to realize simultaneously.Long-time service can promote on vagina
The reparation and regeneration of chrotoplast prevent vagina mucosa aging to be denaturalized, keep the gauffer of vagina mucosa, not only make vagina rich in bullet
Property, and enhance the sensibility of vagina, easily there is orgasm.The present invention prevents AIDS, property to people's life quality is improved
Human health is protected in the propagation of disease, and effectively implementation plan fertility etc. has extraordinary social benefit.
Further, bioactive molecule medical PVA of the present invention, disinfection sanitizer, spermatocide account for solvable respectively
10~40%, 0.05~3.5% and the 0.5~6% of property condom gross mass.
Bioactive molecule medical PVA (PVA) of the present invention is a kind of active medical resin and widely used
One of surfactant.The PVA of PVA especially low alcoholysis level has good water-soluble, film forming and toughness, and chemical property
Stablize.The concentration of aqueous solution of PVA can form a film in 10-40%, lower than 10% form a film very thin and poor toughness, be higher than 40% at
Film toughness difference easy fracture.Disinfection sanitizer is amphoteric surfactant by Tego(carboxylic acid type alpha-imino acetic acid), domiphen and
Minimum effective bacteriocidal concentration of triclosan composition, Tego is 0.5%, and minimum effective bacteriocidal concentration of domiphen is
0.05%, the minimum effective bacteriocidal concentration of triclosan is 0.15%.
The nutrition koro agent is mainly by acid fibroblast growth factor (aFGF), the hydrolysate of elastin laminin, again
The group koro factor, Black Cohosh P.E, Fructus Viticis extract, pycnogenol extract and damiana extract composition.
Acid fibroblast growth factor (aFGF) is a kind of with the extensive trace activity substance for promoting splitting action, energy
Promote cell Proliferation, growth, differentiation, promote wound healing and tissue repair, improve cell life microenvironment, promotes injured nerve
Regeneration and the reparation of blood vessel, muscle, skin etc.;It can promote fibroblast synthesis and secretion collagen, promote elastomer
Synthesis and secretion, promote the increase of intercellular matrix, to increase mucocutaneous elasticity;Promote fibroblast, epidermis thin
Born of the same parents' metabolism, proliferation and growth, accelerate the metabolism and update of cell, have good maintenance action to mucomembranous cell;
Elastin laminin is the main component of elastomer (elastic fibers), and elastomer is the fibre for having rubber-like elasticity
Dimension, can be elongated several times, and can restore as former state, it is the principal element of connective tissue elasticity, therefore has the beauty of " human body rubber "
Claim.Elastomer exists jointly with collagenous fibres, assigns tissue with elasticity and tensile energy.Elastin laminin is with hydrophobic
Macromolecular substances only can just be absorbed by tissue utilization by being hydrolyzed into small molecule.
Koro recombinant factor is human placental extract, has and repairs the impaired mucosal irritation vagina mucosa cytothesis of vagina,
Enhancing vagina includes about machine convergent force, restores the non-tip receptor susceptibility of private parts inner wall nerve.It can be extensive using koro recombinant factor
Complex elasticity and Rythmic contractions characteristic make loosely to shrink powerless vagina change tightly, become have convergent force, become sensitive.
Black Cohosh P.E can produce oestrogen-like hormone sample effect, adjust incretion balance, enhance the reactivity to sexual stimulus.
Fructus viticis can be raised libido by the release of chemical substance dopamine in promoting the secretion and brain of progestational hormone, together
When it can be reduced cause in brain sexual desire decline chemical substance lactogen release, to increase the secretion of vagina.
Pycnogenol can improve microcirculation, promote ovary nutrient absorption, restore ovary normal physiological function, remain normal
Endocrine;It is some research shows that pycnogenol can enhance nitric oxide production generation in blood, enhancement respond.
Damiana improves sexual function for adjusting nervous system, promoting hormonal secretion.
Acid fibroblast growth factor (aFGF) therein, the hydrolysate of elastin laminin, recombination the koro factor, black liter
The nutrition koro agent such as nettle extract, Fructus Viticis extract, pycnogenol extract, damiana extract are negative in 3 minutes
Road mucosa absorption, so that vaginal fluid be made to increase, intravaginal is slightly generated heat, vagina elasticity and gripping force enhancing, and is occurred certainly
Main property is shunk, and purpose of design is reached.
In the feeding koro agent, acid fibroblast growth factor account for soluble condom gross mass 0.001~
0.1%, the hydrolysate of elastin laminin accounts for the 0.2~0.5% of soluble condom gross mass, the recombination koro factor and accounts for soluble safety
It covers the 0.01~0.5% of gross mass, Black Cohosh P.E and accounts for the 1.5~3.0% of soluble condom gross mass, Fructus Viticis extract
Account for the 1.0~3.0% of soluble condom gross mass, pycnogenol extract account for soluble condom gross mass 1.0~3.0%,
Damiana extract accounts for the 1.0~3.0% of soluble condom gross mass.
The concentration of the general minimum effective dose of women acid fibroblast growth factor (aFGF) is 0.001%, is set accordingly
Meter 0.001~0.1% is effective.The hydrolysate of elastin laminin is mostly the solution for the elastin laminin for being 5% containing mass percent,
Its concentration 0.2~0.5% is common additive amount.Recombinating the koro factor is mostly freeze-dried powder, and minimum physiological active concentration is
0.01%;Black Cohosh P.E triterpenoid saponin content is up to 8%, and the general 5-10mg of triterpenoid saponin can show certain physiology
Activity, designing minimum additional amount is 1.5 grams of Black Cohosh P.Es, and triterpenoid saponin content is 120mg, and every product content is 6mg,
It should be effective.The general dosage 1% of fructus viticis 30:1 extract, every product content 50mg have reached effective quantity.Pycnogenol extract
Physiological activity is shown with the general dosage 50mg of damiana extract, the design is also for every product content is reached
50mg and consider.
Disinfection sanitizer of the present invention is amphoteric surfactant by Tego(carboxylic acid type alpha-imino acetic acid), disinfection
Peace triclosan composition.
Combination of the above can dramatically increase the synergistic effect of multiple sterilizing drugs, act on sterilizing at double
Enhancing, and dosage can be significantly reduced, eliminate its adverse reaction.The sterilizing drug energy high aggregation of the combination is in bacterium table
Face changes the permeability of cell, influences the metabolism of bacterium, ruptures thallus, protein denaturation, and inactivation of bacterial virion
The enzyme system of interior dehydrogenase, oxidizing ferment and decomposition glucose, succinate, acetonate, so that it is thin to play powerful killing
Bacterium virus function prevents AIDS, venereal disease from propagating by sexual behaviour, while having to the common genital infection disease of women
Good efficacy.
The spermatocide is nonoxinol, can also be made of chlorohexidene and pungent menthylphenoxypolyethoxy ethanol.Spermatocide passes through change
The osmotic pressure of sperm destroys the direct inactivating sperm of cell membrane of sperm, to generate reliable contraceptive effect.While chlorohexidene,
Pungent menthylphenoxypolyethoxy ethanol, nonoxinol are surfactant, can generate macrofoam in use, and foam can close cervix, are prevented
Sperm enters uterus.
The present invention is another object is that propose the production method with the soluble condom of koro function.
Bioactive molecule medical PVA is dissolved with glycerol and water, obtains the glycerite of polyvinyl alcohol;Sterilization is disappeared
Toxic agent, spermatocide and nutrition koro agent first with propylene glycol and water mixing after, then mix with the glycerite of polyvinyl alcohol, obtain
Mixed solution makes the nutrition koro agent account for the 4.711~13% of mixed solution gross mass;Again by mixed solution with mould shape,
Dry in 20~95 DEG C of temperature environments, then demoulding, disinfection by ultraviolet light are to get the solubility safety with koro function
Set.
Production method of the present invention and the production method that convention security covers are similar, can be formed and condom shape by mold
The identical product of shape.Production method of the present invention simply, conveniently, safely, is conducive to batch production, and product stability is good.
When production, the bioactive molecule medical PVA, disinfection sanitizer, spermatocide account for the total matter of mixed solution respectively
10~40%, 0.05~3.5% and the 1~6% of amount.
The feeding koro agent is mainly by acid fibroblast growth factor (aFGF), the hydrolysate of elastin laminin, recombination
The koro factor, Black Cohosh P.E, Fructus Viticis extract, pycnogenol extract and damiana extract composition;The mixing
In solution gross mass, the hydrolysate that acid fibroblast growth factor accounts for 0.001~0.1%, elastin laminin accounts for 0.2~0.5%,
The recombination koro factor, which accounts for 0.01~0.5%, Black Cohosh P.E and accounts for 1.5~3.0%, Fructus Viticis extract, accounts for 1.0~3.0%, green trailing plants
Root of Dahurian angelica extract accounts for 1.0~3.0%, damiana extract and accounts for 1.0~3.0%.
The disinfection sanitizer is amphoteric surfactant by Tego(carboxylic acid type alpha-imino acetic acid), domiphen and two
Chlorobenzene oxygen chlorophenol composition, ego(carboxylic acid type alpha-imino acetic acid system amphoteric surfactant), domiphen and Dichlorophenoxy chlorine
Phenol accounts for 0.5~2.0%, 0.05~1.0%, the 0.15~0.5% of mixed solution gross mass respectively.
Specific embodiment
One, production technology:
1, it stocks up:
Disinfection sanitizer: being amphoteric surfactant by Tego(, that is, carboxylic acid type alpha-imino acetic acid) 0.3~2.0g, domiphen
0.05~1.0g, triclosan (such as triclosan nanometer water dispersant (Oletron TM)) 0.15~2.0g composition.
Spermatocide: 0.5~6g of union menthylphenoxypolyethoxy ethanol;Or 0.1~0.5g of chlorohexidene, pungent 0.25~4.0g of menthylphenoxypolyethoxy ethanol composition.
Bioactive molecule medical PVA: 10~40g.
Nutrition koro agent: by 0.001~0.1 g of acid fibroblast growth factor, elastin laminin hydrolysate 0.2~
0.5 g, recombination 0.01~0.5g of the koro factor, 1.5~3.0g of Black Cohosh P.E, 1.0~3.0g of Fructus Viticis extract, green trailing plants
1.0~3.0g of root of Dahurian angelica extract, damiana 1.0~3.0g of extract, total amount are 4.711~13g.
Glycerol: 5~10mL.
Propylene glycol: 5~10mL.
Purified water: 20~70mL.
2, production technology:
Appropriate purified water stirring further dissolution will be added after the wet dispersion of glycerol of bioactive molecule medical PVA, obtains poly-
The glycerite of vinyl alcohol.
After disinfection sanitizer, spermatocide, nutrition koro agent are moistened dispersion mixing with propylene glycol, appropriate purifying is added
Water is agitated to be reached and is completely dissolved, and is then added into the glycerite of polyvinyl alcohol and is mixed, supplementing appropriate purified water makes to mix
The gross mass for closing solution reaches 100mL, and nutrition koro agent accounts for the 4.711~13% of mixed solution gross mass, obtains for producing
The mixed solution 100mL of condom.
Above-mentioned mixed solution is passed through into mould shape, it is 30 minutes dry in 20~95 DEG C of temperature environments, then it is atomized
Demoulding, then through disinfection by ultraviolet light to get the soluble condom with koro function.
Two, products characteristics:
The present invention has and the same shape, approximate elastic and identical of existing rubber condoms, soluble disinfecting condom
Application method.
Sperm can be killed using product of the present invention 1 minute, to effectively prevent additional birth;It can kill within 2 minutes
Go out AIDS virus, human papilloma virus, herpesviral, diplococcus, microspironema pallidum, Chlamydia, mycoplasma and other
Pathogenic bacteria reliably prevent AIDS, venereal disease is propagated by sexual behaviour, while had to the common genital infection disease of women
Good therapeutic effect;Apparent vagina contraction can be generated within 3 minutes, meet sexual life.Product of the present invention is free of rubber
Ingredient, unplessantness displeasure when will not generate using rubber sleeve will not also generate allergic reaction, less have carcinogenic worry.
Claims (10)
1. a kind of soluble condom with koro function, including bioactive molecule medical PVA, disinfection sanitizer, spermicidal
Sub- agent, solvent, it is characterised in that further include 4.711~13% nutrition koro agent for accounting for soluble condom gross mass.
2. soluble condom according to claim 1, it is characterised in that the bioactive molecule medical PVA, sterilization disappear
Toxic agent, spermatocide account for 10~40%, 0.05~3.5% and the 1~6% of soluble condom gross mass respectively.
3. soluble condom according to claim 1, it is characterised in that the feeding koro agent is mainly thin by acid fibroblast
The intracellular growth factor, the hydrolysate of elastin laminin, the recombination koro factor, Black Cohosh P.E, Fructus Viticis extract, pycnogenol extract
Object and damiana extract composition.
4. soluble condom according to claim 3, it is characterised in that in the feeding koro agent, acidic fibroblast is raw
The hydrolysate that the long factor accounts for the 0.001~0.1% of soluble condom gross mass, elastin laminin accounts for soluble condom gross mass
0.2~0.5%, the recombination koro factor accounts for the 0.01~0.5% of soluble condom gross mass, Black Cohosh P.E and accounts for solubility
Condom gross mass 1.5~3.0%, Fructus Viticis extract accounts for the 1.0~3.0% of soluble condom gross mass, pycnogenol and mentions
Take object account for the 1.0~3.0% of soluble condom gross mass, damiana extract account for soluble condom gross mass 1.0~
3.0%。
5. soluble condom according to claim 1, it is characterised in that the disinfection sanitizer is by Tego, domiphen and two
Chlorobenzene oxygen chlorophenol composition.
6. soluble condom according to claim 1, it is characterised in that the spermatocide is nonoxinol or chlorohexidene
With pungent menthylphenoxypolyethoxy ethanol.
7. the production method of the soluble condom with koro function as described in claim 1, it is characterised in that: by activity point
Sub- medical PVA is dissolved with glycerol and water, obtains the glycerite of polyvinyl alcohol;By disinfection sanitizer, spermatocide and battalion
Support koro agent first with propylene glycol and water mixing after, then mix with the glycerite of polyvinyl alcohol, obtain mixed solution, make the battalion
It supports koro agent and accounts for the 4.711~13% of mixed solution gross mass;Again by mixed solution with mould shape, then at 20~95 DEG C of temperature
Dry in environment, then demoulding, disinfection by ultraviolet light are to get the soluble condom with koro function.
8. production method according to claim 7, it is characterised in that: the bioactive molecule medical PVA, sterilization disappear
Toxic agent, spermatocide account for 10~40%, 0.05~3.5% and the 0.5~6% of mixed solution gross mass respectively.
9. production method according to claim 7, it is characterised in that: the nutrition koro agent is mainly thin by acid fibroblast
The intracellular growth factor, the hydrolysate of elastin laminin, the recombination koro factor, Black Cohosh P.E, Fructus Viticis extract, pycnogenol extract
Object and damiana extract composition;In the mixed solution gross mass, acid fibroblast growth factor accounts for 0.001~
0.1%, the hydrolysate of elastin laminin account for 0.2~0.5%, the recombination koro factor account for 0.01~0.5%, Black Cohosh P.E account for 1.5~
3.0%, Fructus Viticis extract account for 1.0~3.0%, pycnogenol extract account for 1.0~3.0%, damiana extract account for 1.0~
3.0%。
10. production method according to claim 7, it is characterised in that: the disinfection sanitizer is by Tego, domiphen and two
Chlorobenzene oxygen chlorophenol composition, the Tego, domiphen and triclosan account for respectively mixed solution gross mass 0.5~2.0%,
0.05~1.0%, 0.15~0.5%.
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Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1271578A (en) * | 1999-04-28 | 2000-11-01 | 孙廷柱 | Soluble disinfecting condom |
CN103405591A (en) * | 2013-05-30 | 2013-11-27 | 闫一粼 | Nourishing type water-soluble personal lubricant and preparation method thereof, and condom |
CN104872521A (en) * | 2015-06-05 | 2015-09-02 | 高鲁明 | Natural health-care food favorable for increasing quality of sexual life and production process thereof |
CN107325529A (en) * | 2017-08-15 | 2017-11-07 | 李俊杰 | A kind of composite ultra-thin flexible condom and preparation method thereof |
-
2018
- 2018-08-03 CN CN201810874354.7A patent/CN108939171A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1271578A (en) * | 1999-04-28 | 2000-11-01 | 孙廷柱 | Soluble disinfecting condom |
CN103405591A (en) * | 2013-05-30 | 2013-11-27 | 闫一粼 | Nourishing type water-soluble personal lubricant and preparation method thereof, and condom |
CN104872521A (en) * | 2015-06-05 | 2015-09-02 | 高鲁明 | Natural health-care food favorable for increasing quality of sexual life and production process thereof |
CN107325529A (en) * | 2017-08-15 | 2017-11-07 | 李俊杰 | A kind of composite ultra-thin flexible condom and preparation method thereof |
Non-Patent Citations (7)
Title |
---|
(美)埃米尔: "《家庭诊疗全书》", 28 February 2010, 中央编译出版社 * |
刘自力: "《救世良方文献研究》", 31 December 2007, 云南民族出版社 * |
方瑾: "《成人高等教育基础医学教材 细胞生物学》", 31 July 2011, 上海科学技术出版社 * |
杨尔滨: "《营养素补充剂面面观》", 31 January 2007, 广西民族出版社 * |
赵长峰等: "《老年健康饮食督导》", 31 January 2003, 山东人民出版社 * |
陈志南: "《中华医学百科全书 生物药物学》", 31 May 2017, 中国协和医科大学出版社 * |
陈馥馨: "《新编中成药手册》", 31 March 1991, 中国医药科技出版社 * |
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