CN108939026A - It is a kind of can blood-enrich medlar red date particle and preparation method thereof - Google Patents

It is a kind of can blood-enrich medlar red date particle and preparation method thereof Download PDF

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CN108939026A
CN108939026A CN201810825642.3A CN201810825642A CN108939026A CN 108939026 A CN108939026 A CN 108939026A CN 201810825642 A CN201810825642 A CN 201810825642A CN 108939026 A CN108939026 A CN 108939026A
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parts
blood
enrich
red date
oyster
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胡寅道
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Taihe County 39 Pharmaceutical Co Ltd
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Taihe County 39 Pharmaceutical Co Ltd
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A61K31/51—Thiamines, e.g. vitamin B1
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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    • A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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Abstract

The invention discloses a kind of energy blood-enrich medlar red date particles and preparation method thereof; it is related to technical field of traditional Chinese medicines, raw material includes: 27-40 parts of fructus lycii, 23-35 parts of jujube, 7-15 parts of oyster, 15-25 parts of fructus alpiniae oxyphyllae, 7-15 parts of hawthorn, 15-25 parts of Poria cocos, 7-15 parts of lotus leaf, 5-10 parts of baked ginger, 10-20 parts of fructus amomi, 5-10 parts of lotus seeds, 0.1-0.5 parts of taurine, 0.01-0.03 parts of vitamin B1 by weight.The selected fructus lycii of the present invention, jujube, oyster, fructus alpiniae oxyphyllae, hawthorn, Poria cocos, lotus leaf, baked ginger, fructus amomi, a variety of integration of drinking and medicinal herbs medicinal materials such as lotus seeds, and add taurine and vitamin B1, each mutually auxiliary help of raw material, strengthening the spleen and stomach is played altogether, QI invigorating helps digestion, tranquilizing the mind is reposed, the effect of brain-nourishing intelligence-benefiting, enhance child's autoimmunity, adjust its taste health, it is effectively improved diarrhea, abdominal distension, night sweat, tired mind, easy catching a cold is sick, clinical symptoms that malnutrition etc. is weakness of the spleen and the stomach, promote upgrowth and development of children, and the granular preparation has no toxic side effect, cure rate is high, it can feel at ease to be eaten for a long time.

Description

It is a kind of can blood-enrich medlar red date particle and preparation method thereof
Technical field
The present invention relates to technical field of traditional Chinese medicines more particularly to a kind of energy blood-enrich medlar red date particle and its preparation sides Method.
Background technique
Chinese medicine thinks that spleen is children's sheet, and many diseases are derived from taste.Child is weakness of the spleen and the stomach, and clinical manifestation has: the course of disease compared with It is long, when diarrhea, is light weight or when stop when sending out, loose watery stool, the light odorless of color accompanies indigestion swill, easily rushes down, eat after food See that abdominal distension, stool are more after more, usually loss of appetite, sallow complexion is tired, and body is thin and weak, and tongue nature is light, and tongue fur is thin white.Taste Weak child often gynecological ailments, with malnutrition, anaemia, rickets etc., growth and development is slow compared with normal child, and can go out Existing spontaneous sweating, the morbid night crying of babies, anorexia, hair sparse lack gloss, pale complexion or sallow, and fatigue and weakness is often caught a cold, cough Etc. symptoms.Control should with strengthening the spleen and replenishing qi, help transporting wet.It is existing for treating weakness of the spleen and the stomach Chinese medicine due to originals such as prescriptions on the market Cause, effect residual error is uneven, not satisfactory.
Summary of the invention
Technical problems based on background technology, the invention proposes it is a kind of can blood-enrich medlar red date particle and its Preparation method, the granular preparation can enhance child's autoimmunity, adjust taste health, are effectively improved diarrhea, abdominal distension, robber Sweat, tired mind, easy catching a cold be sick, the weakness of the spleen and the stomach clinical symptoms such as malnutritive, promotes upgrowth and development of children, and nontoxic secondary makees With.
A kind of energy blood-enrich medlar red date particle proposed by the present invention, raw material includes: fructus lycii 27-40 by weight Part, 23-35 parts of jujube, 7-15 parts of oyster, 15-25 parts of fructus alpiniae oxyphyllae, 7-15 parts of hawthorn, 15-25 parts of Poria cocos, 7-15 parts of lotus leaf, big gun 5-10 parts of ginger, 10-20 parts of fructus amomi, 5-10 parts of lotus seeds, 0.1-0.5 parts of taurine, 0.01-0.03 parts of vitamin B1.
Preferably, the oyster is the calcined oyster shell that fumed 2-4h is obtained at 200-300 DEG C.
The invention also provides the preparation methods of the above-mentioned medlar red date particle for having blood-enrich, comprising the following steps:
S1, fructus alpiniae oxyphyllae, baked ginger, fructus amomi, Poria cocos, lotus leaf being crushed, 65-70% ethanol solution refluxing extraction is added in mixing, Filtering, obtains alcohol extract and filter residue a；
S2, oyster is crushed, is soaked in water, then ultrasound is added fructus lycii, jujube, hawthorn, lotus seeds and filter residue a, adds Water is decocted and is extracted, and filtering obtains Aqueous extracts and filter residue b；
S3, Aqueous extracts are concentrated under reduced pressure, ethyl alcohol is added to concentrate and adjusts alcohol content, filtering obtains refining liquid；
S4, refining liquid and alcohol extract are mixed, recycles ethyl alcohol, is concentrated under reduced pressure into thick paste, taurine, dimension life is added to thick paste Plain B1, sucrose and dextrin mix, granulation, it is dry to get.
Preferably, in the S1, refluxing extraction 1-2h.
Preferably, in the S2, oyster is crushed, soaks in water 20-30min, then the ultrasound 20- at 40-50 DEG C 30min；Preferably, it decocts and extracts 2-3h.
Preferably, in the S3, Aqueous extracts is concentrated under reduced pressure into the clear cream that relative density is 1.05-1.10, ethyl alcohol is added Alcohol content is adjusted to 70-75%.
Preferably, the relative density of the thick paste is 1.28-1.32.
Preferably, the thick paste, sucrose, cyclodextrin weight ratio be 1:2.4-3.0:0.9-1.2.
It is as follows the effect of each material medicine in the present invention:
Fructus lycii: mild-natured, sweet in flavor, return liver warp, kidney channel have effects that nourishing liver and kidney, benefiting shrewd head, with control consumption consumptive loss, Soreness of waist and knee joint, dizziness and tinnitus, Heat Diabetes, blood deficiency chlorosis, blurred vision；Pharmacological testing show fructus lycii have enhancing immune function, Anti-aging, liver protection, promotes the effects of hematopoiesis function, anti-genetic damage, hypoglycemic, blood pressure lowering at antitumor, reducing blood lipid.
Jujube: warm-natured, sweet in flavor, converge to the spleen channel, stomach meridian, the heart channel of Hang-Shaoyin have effects that tonifying middle-Jiao and Qi, nourishing blood and tranquilization, with controlling spleen deficiency Deficiency of food, qi-blood-body fluid are insufficient, loose stool out of strength, and pharmacological testing shows that jujube has central inhibitory action, protect liver, enhancing muscular strength, resistance State reaction, antifatigue, antitumor, calm peace increase leucocyte cAMP, enhance the functions such as immune.
Oyster: cold nature, taste is salty, return liver warp, gallbladder channel, kidney channel, has transquilization with heavy material, checking exuberance of yang and tonifying yin, the function of resolving hard lump Effect, with controlling insomnia of palpitating with fear, dizziness and tinnitus, scrofula oyster subcutaneous nodule, abdominal mass and lump；Animal experiments show that there is oyster extract enhancing to exempt from Epidemic disease, calmness, anti-experimental character gastric ulcer, antiatherosclerosis, anti-inflammatory and anti-aging effects.
Fructus alpiniae oxyphyllae: warm-natured, acrid flavour, converge to the spleen channel, kidney channel, have effects that it is warming spleen and stopping diarrha, take the photograph saliva, warm kidney, astringent sperm contracting urine, use Control malaria diarrhea, crymodynia, the more salivas of mouth, enuresis with renal asthenia, frequent urination, spermatorrhea gonorrhoea in abdomen.
Hawthorn: slightly warm in nature, sour, sweet, converge to the spleen channel, stomach meridian, Liver Channel have effects that digestion-promoting spleen-invigorating, moistening lung qi-benefitting, treatment Meat stagnation, children's cream product, abdominal distention, dysentery, diarrhea, dysmenorrhea, postpartum blood stasis abdominal pain, hyperlipemia etc..
Poria cocos: mild-natured, sweet in flavor, light, thoughts of returning home warp, lung channel, the spleen channel, kidney channel have effects that clearing damp and promoting diuresis, invigorating the spleen calming heart, With controlling edema and little urine, phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear；Pharmacological evaluation shows there is benefit Urine, antibacterial action, can improve the immunocompetence of body.
Lotus leaf: mild-natured, bitter, return liver warp, the spleen channel, stomach meridian have the effect of clearing away summer-heat and eliminating dampness, sending up the lucid yang, cooling blood and hemostasis, For hot summer weather polydipsia, summer heat damp diarrhea, splenasthenic diarrhea, blood-head tells nosebleed, uterine bleeding of having blood in stool.
Baked ginger: warm-natured, bitter, pungent, converge to the spleen channel, stomach meridian, the heart channel of Hang-Shaoyin, kidney channel, lung channel, with warming spleen and stomach for dispelling cold, warming channel for arresting bleeding Effect is used for deficiency-cold in spleen and stomach, and abdominal pain is vomited and diarrhoea, hematemesis metrorrhagia and metrostaxis, deficiency of yang blood loss.
Fructus amomi: warm-natured, acrid flavour returns stomach meridian, the spleen channel, kidney channel, has effects that dampness elimination appetizing, warming spleen and stopping diarrha, qi-regulating, with controlling Edema swelling, constipation and anuresis, phlegm retention accumulation, the circulation of vital energy in the wrong direction breath with cough, abdominal pain due to enterositosis, roundworm, the diseases such as tapeworm.Pharmacological testing shows to have anti- Platelet aggregation, expansion blood vessel inhibit pepsin activity, gastric acid secretion inhibiting, promote the effects of intestinal movement, analgesia.
Lotus seeds: mild-natured, sweet in flavor, puckery, converge to the spleen channel, kidney channel, the heart channel of Hang-Shaoyin, with tonifying spleen and stopping diarrhea, supplementing the kidney to control the nocturnal, mental-tranquilization function Effect, with control spleen deficiency chronic diarrhea, spermatorrhea leukorrhagia, palpitation and insomnia.
Taurine: also known as β-aminoethanesulfonic acid is a kind of non-protein amino acid of sulfur-bearing, is deposited in vivo with free state It is being not involved in the biosynthesis of vivo protein, but it is closely related with the metabolism of cystine, cysteine；Human body synthesizes ox Cysteine sulfurous acid carboxylic acid (CSAD) activity of sulfonic acid is lower, relies primarily on the taurine in intake food to meet body need It wants.Taurine in the rich content, widely distributed of intracerebral, can be obviously promoted nervous system growth and development and cell Proliferation, point Change, and be in dose dependent, play an important role in cranial nerve cell growth course, as taurine supplements deficiency, it will make children Youngster's growth and development slowly, mental retardation；Taurine can also improve endocrinosity, enhance human immunity, antifatigue, improve Memory function.
Vitamin B1: it is referred to as psychogenic vitamin, has desirable influence to nerve fiber and the state of mind, mainly control Treat the prevention and treatment of Vitamin B1 deficiency, such as " athlete's foot ", peripheral neuritis and indigestion.
The utility model has the advantages that the selected a variety of natural plants fructus lyciis of the present invention, jujube, oyster, fructus alpiniae oxyphyllae, hawthorn, Poria cocos, lotus leaf, Baked ginger, fructus amomi, lotus seeds are integration of drinking and medicinal herbs medicinal material, and add taurine and vitamin B1, and each mutually auxiliary help of raw material is played strong altogether The effect of spleen stomach function regulating, QI invigorating help digestion, tranquilizing the mind is reposed, brain-nourishing intelligence-benefiting enhances child's autoimmunity, adjusts its taste health, uses In diseases such as weakness of the spleen and the stomach, loss of appetite, abdominal distention, diarrhea of getting ill from overeating, it is effectively improved diarrhea, abdominal distension, night sweat, tired mind, easily It catches a cold the clinical symptoms such as sick, malnutritive, promotes upgrowth and development of children, strengthen immunity, which has no toxic side effect, Easy to use, cure rate is high, can feel at ease to be eaten for a long time.
Specific embodiment
In the following, technical solution of the present invention is described in detail by specific embodiment.
Embodiment 1
It is proposed by the present invention it is a kind of can blood-enrich medlar red date particle, raw material includes: 27 parts of fructus lycii by weight, red 35 parts of jujube, 7 parts of oyster, 25 parts of fructus alpiniae oxyphyllae, 7 parts of hawthorn, 15 parts of Poria cocos, 15 parts of lotus leaf, 10 parts of baked ginger, 10 parts of fructus amomi, lotus seeds 10 Part, 0.1 part of taurine, 0.01 part of vitamin B1.
The invention also provides the preparation methods of the above-mentioned medlar red date particle for having blood-enrich, comprising the following steps:
S1, fructus alpiniae oxyphyllae, baked ginger, fructus amomi, Poria cocos, lotus leaf are crushed, 70% second of 5 times of medicinal material initial masses is added in mixing Alcoholic solution refluxing extraction 1h, filtering, obtains alcohol extract and filter residue a；
S2, oyster is crushed, 3 times of water is added to impregnate 20min, then the ultrasound 20min at 40 DEG C, then addition fructus lycii, jujube, Hawthorn, lotus seeds and filter residue a add water to 6 times of medicinal material initial mass, decoct and extract 2h, and filtering obtains Aqueous extracts and filter residue b；
S3, Aqueous extracts are concentrated under reduced pressure into the clear cream that relative density is 1.05, addition ethyl alcohol adjusting alcohol content to 70%, mistake Filter, obtains refining liquid；
S4, refining liquid and alcohol extract are mixed, recycles ethyl alcohol, be concentrated under reduced pressure into the thick paste that relative density is 1.28, to thick Taurine, vitamin B1, sucrose and dextrin is added in cream, mixes, granulation, it is dry to get.
Embodiment 2
It is proposed by the present invention it is a kind of can blood-enrich medlar red date particle, raw material includes: 40 parts of fructus lycii by weight, red 23 parts of jujube, 15 parts of oyster, 15 parts of fructus alpiniae oxyphyllae, 15 parts of hawthorn, 25 parts of Poria cocos, 7 parts of lotus leaf, 5 parts of baked ginger, 20 parts of fructus amomi, lotus seeds 5 Part, 0.5 part of taurine, 0.03 part of vitamin B1；Wherein oyster be fumed 2h is obtained at 200 DEG C calcined oyster shell.
The invention also provides the preparation methods of the above-mentioned medlar red date particle for having blood-enrich, comprising the following steps:
S1, fructus alpiniae oxyphyllae, baked ginger, fructus amomi, Poria cocos, lotus leaf are crushed, 65% second of 8 times of medicinal material initial masses is added in mixing Alcoholic solution refluxing extraction 2h, filtering, obtains alcohol extract and filter residue a；
S2, oyster is crushed, 5 times of water is added to impregnate 30min, then the ultrasound 30min at 50 DEG C, then addition fructus lycii, jujube, Hawthorn, lotus seeds and filter residue a add water to 10 times of medicinal material initial mass, decoct and extract 3h, and filtering obtains Aqueous extracts and filter residue b；
S3, Aqueous extracts are concentrated under reduced pressure into the clear cream that relative density is 1.10, addition ethyl alcohol adjusting alcohol content to 75%, mistake Filter, obtains refining liquid；
S4, refining liquid and alcohol extract are mixed, recycles ethyl alcohol, be concentrated under reduced pressure into the thick paste that relative density is 1.32, to thick Cream is added taurine, vitamin B1, sucrose and dextrin, thick paste, sucrose, cyclodextrin weight ratio be 1:3.0:0.9, mix, system Grain, it is dry to get.
Embodiment 3
It is proposed by the present invention it is a kind of can blood-enrich medlar red date particle, raw material includes: 30 parts of fructus lycii by weight, red 28 parts of jujube, 12 parts of oyster, 22 parts of fructus alpiniae oxyphyllae, 12 parts of hawthorn, 18 parts of Poria cocos, 10 parts of lotus leaf, 8 parts of baked ginger, 15 parts of fructus amomi, lotus seeds 8 Part, 0.4 part of taurine, 0.03 part of vitamin B1；Wherein oyster be fumed 4h is obtained at 300 DEG C calcined oyster shell.
The invention also provides the preparation methods of the above-mentioned medlar red date particle for having blood-enrich, comprising the following steps:
S1, fructus alpiniae oxyphyllae, baked ginger, fructus amomi, Poria cocos, lotus leaf are crushed, 67% second of 6 times of medicinal material initial masses is added in mixing Alcoholic solution refluxing extraction 1.5h, filtering, obtains alcohol extract and filter residue a；
S2, oyster is crushed, 4 times of water is added to impregnate 25min, then the ultrasound 25min at 45 DEG C, then addition fructus lycii, jujube, Hawthorn, lotus seeds and filter residue a add water to 7 times of medicinal material initial mass, decoct and extract 2h, and filtering obtains Aqueous extracts and filter residue b；
S3, Aqueous extracts are concentrated under reduced pressure into the clear cream that relative density is 1.07, addition ethyl alcohol adjusting alcohol content to 70%, mistake Filter, obtains refining liquid；
S4, refining liquid and alcohol extract are mixed, recycle ethyl alcohol, be concentrated under reduced pressure into the thick paste that relative density is 1.28-1.32, Be added taurine, vitamin B1, sucrose and dextrin to thick paste, thick paste, sucrose, cyclodextrin weight ratio be 1:2.4:1.2, mix It is even, granulation, it is dry to get.
Embodiment 4
It is proposed by the present invention it is a kind of can blood-enrich medlar red date particle, raw material includes: 33 parts of fructus lycii by weight, red 30 parts of jujube, 10 parts of oyster, 20 parts of fructus alpiniae oxyphyllae, 10 parts of hawthorn, 20 parts of Poria cocos, 12 parts of lotus leaf, 6 parts of baked ginger, 18 parts of fructus amomi, lotus seeds 6 Part, 0.3 part of taurine, 0.02 part of vitamin B1；Wherein oyster be fumed 3h is obtained at 250 DEG C calcined oyster shell.
The invention also provides the preparation methods of the above-mentioned medlar red date particle for having blood-enrich, comprising the following steps:
S1, fructus alpiniae oxyphyllae, baked ginger, fructus amomi, Poria cocos, lotus leaf are crushed, 65% second of 7 times of medicinal material initial masses is added in mixing Alcoholic solution refluxing extraction 2h, filtering, obtains alcohol extract and filter residue a；
S2, oyster is crushed, 3 times of water is added to impregnate 20min, then the ultrasound 30min at 45 DEG C, then addition fructus lycii, jujube, Hawthorn, lotus seeds and filter residue a add water to 8 times of medicinal material initial mass, decoct and extract 2.5h, and filtering obtains Aqueous extracts and filter residue b；
S3, Aqueous extracts are concentrated under reduced pressure into the clear cream that relative density is 1.08, addition ethyl alcohol adjusting alcohol content to 72%, mistake Filter, obtains refining liquid；
S4, refining liquid and alcohol extract are mixed, recycle ethyl alcohol, be concentrated under reduced pressure into the thick paste that relative density is 1.28-1.32, Be added taurine, vitamin B1, sucrose and dextrin to thick paste, thick paste, sucrose, cyclodextrin weight ratio be 1:2.7:1.1, mix It is even, it pelletizes, dry, pack, 5g/ bags to get the medlar red date particle beneficial to infant spleen-tonifying.
Comparative example 1
Compared with Example 4, vitamin B1 is not contained, remaining is all the same.
Comparative example 2
Compared with Example 4, taurine is not contained, remaining is all the same.
The medlar red date particle prepared by the present invention for having blood-enrich is used for the spleen and stomach in children weakness.
1, case selection: selecting the weakness of the spleen and the stomach infant 300 accepted for medical treatment, and patient age is 6 months to 12 years old, average age 6.8 years old, clinical manifestation are as follows: the course of disease is longer, when diarrhea, is light weight or when stop when sending out, loose watery stool, the light odorless of color accompanies and does not disappear Change swill, easily rushed down after food, sees that abdominal distension, stool are more after eating mostly, usually loss of appetite, sallow complexion is tired, and body is thin Weak, tongue nature is light, and tongue fur is thin white, meets the diagnostic criteria of the spleen and stomach in children weakness.3 groups are classified as, every group of 100 people, 3 groups without significant Property group difference.
2, treatment method: 3 groups of infants take respectively prepared in the embodiment of the present invention 4, comparative example 1 and comparative example 2 it is beneficial The medlar red date particle that gas is enriched blood, boiled water are taken after mixing it with water, and each half bag below three one full year of life, two times a day, three more than one full year of life 1 bag every time, Two times a day, seven it is more than one full year of life once 2 bags, two times a day.10 days are 1 course for the treatment of, continuously take 3 course for the treatment of observation curative effects.
3, efficacy determination:
Cure: symptom disappears；
Improve: clinical symptoms are relieved；
Invalid: clinical symptoms are not improved or aggravate.
4, result:
Healing/people Improvement/people In vain/people Effective percentage/%
Embodiment 4 87 13 0 100
Comparative example 1 73 22 5 95
Comparative example 2 67 25 8 92
Through clinical treatment, controlled observation is found out, the medlar red date particle for having blood-enrich of the invention is used for the spleen and stomach in children Weakness, definite effect do not find any toxic side effect in the treatment.
5, typical case
Talk certain: female, 4 years old, loss of appetite often caught a cold or even wants within one month repeated cold several times, takes implementation of the present invention After 3 courses for the treatment of of the medlar red date particle for having blood-enrich of example 4, appetite improves, and weight obviously increases 0.6 kilogram, does not during which have Occurred flu, and later six months in sick number also substantially reduce.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto, Anyone skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.

Claims (8)

1. a kind of can blood-enrich medlar red date particle, which is characterized in that its raw material includes: 27-40 parts of fructus lycii by weight, red 23-35 parts of jujube, 7-15 parts of oyster, 15-25 parts of fructus alpiniae oxyphyllae, 7-15 parts of hawthorn, 15-25 parts of Poria cocos, 7-15 parts of lotus leaf, baked ginger 5-10 Part, 10-20 parts of fructus amomi, 5-10 parts of lotus seeds, 0.1-0.5 parts of taurine, 0.01-0.03 parts of vitamin B1.
2. the medlar red date particle according to claim 1 for having blood-enrich, which is characterized in that the oyster is in 200- The calcined oyster shell that fumed 2-4h is obtained at 300 DEG C.
3. the preparation method of the medlar red date particle of beneficial infant spleen-tonifying according to claim 1 or 2, which is characterized in that The following steps are included:
S1, fructus alpiniae oxyphyllae, baked ginger, fructus amomi, Poria cocos, lotus leaf are crushed, 65-70% ethanol solution refluxing extraction, mistake is added in mixing Filter, obtains alcohol extract and filter residue a；
S2, oyster is crushed, is soaked in water, then ultrasound is added fructus lycii, jujube, hawthorn, lotus seeds and filter residue a, adds water, decoct Extraction is boiled, filters, obtains Aqueous extracts and filter residue b；
S3, Aqueous extracts are concentrated under reduced pressure, ethyl alcohol is added to concentrate and adjusts alcohol content, filtering obtains refining liquid；
S4, refining liquid and alcohol extract are mixed, recycles ethyl alcohol, is concentrated under reduced pressure into thick paste, taurine, vitamin is added to thick paste B1, sucrose and dextrin mix, granulation, it is dry to get.
4. the preparation method of the medlar red date particle according to claim 3 for having blood-enrich, which is characterized in that the S1 In, refluxing extraction 1-2h.
5. the preparation method of the medlar red date particle according to claim 3 or 4 for having blood-enrich, which is characterized in that institute It states in S2, oyster is crushed, soak in water 20-30min, then the ultrasound 20-30min at 40-50 DEG C；Preferably, it decocts and extracts 2-3h。
6. according to the preparation method of the medlar red date particle as claimed in claim 3 to 5 for having blood-enrich, which is characterized in that In the S3, Aqueous extracts are concentrated under reduced pressure into the clear cream that relative density is 1.05-1.10, ethyl alcohol is added and adjusts alcohol content to 70- 75%.
7. according to the preparation method of any medlar red date particle for having blood-enrich of claim 3-6, which is characterized in that The relative density of the thick paste is 1.28-1.32.
8. according to the preparation method of any medlar red date particle for having blood-enrich of claim 3-7, which is characterized in that The thick paste, sucrose, cyclodextrin weight ratio be 1:2.4-3.0:0.9-1.2.
CN201810825642.3A 2018-07-25 2018-07-25 It is a kind of can blood-enrich medlar red date particle and preparation method thereof Pending CN108939026A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112998257A (en) * 2021-03-29 2021-06-22 戴清桂 Dietetic therapy composition and preparation method thereof
CN113384539A (en) * 2021-06-22 2021-09-14 安徽三义堂中药饮片有限公司 Granular tea for tonifying spleen and kidney and removing dampness and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN103656556A (en) * 2012-09-18 2014-03-26 刘志勇 Traditional Chinese medicinal composition for supplementing qi and promoting production of body fluid and preparation method thereof
CN107096007A (en) * 2017-04-13 2017-08-29 中唐慈幼（北京）生物科技有限公司 A kind of postpartum recuperating composition and preparation method thereof

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
CN103656556A (en) * 2012-09-18 2014-03-26 刘志勇 Traditional Chinese medicinal composition for supplementing qi and promoting production of body fluid and preparation method thereof
CN107096007A (en) * 2017-04-13 2017-08-29 中唐慈幼（北京）生物科技有限公司 A kind of postpartum recuperating composition and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112998257A (en) * 2021-03-29 2021-06-22 戴清桂 Dietetic therapy composition and preparation method thereof
CN113384539A (en) * 2021-06-22 2021-09-14 安徽三义堂中药饮片有限公司 Granular tea for tonifying spleen and kidney and removing dampness and preparation method thereof

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Application publication date: 20181207