CN108938997A - A kind of compound preparation for treating multiple dermatosis - Google Patents

A kind of compound preparation for treating multiple dermatosis Download PDF

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Publication number
CN108938997A
CN108938997A CN201710376245.8A CN201710376245A CN108938997A CN 108938997 A CN108938997 A CN 108938997A CN 201710376245 A CN201710376245 A CN 201710376245A CN 108938997 A CN108938997 A CN 108938997A
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China
Prior art keywords
parts
preparation
vinegar
edible
treating multiple
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Chinese (zh)
Inventor
白建权
白格霖
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Individual
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Individual
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
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    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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Abstract

The present invention provides a kind of compound preparation for treating multiple dermatosis, plays the role of removing toxic substances and dispel to itch, and the various color spots of skin, moisturizing analgesic are eliminated in dehumidifying wind-dispelling;Can treat skin by occur after the invasion such as " chill is wet " perverse trends eczema, nettle rash, acne rosacea, rhinitis, verruca plana, whole body itch, monkey, tinea pedis, psoriasis, leucoderma, sufferings caused by bite by mosquitos disease and because in vivo it is damp and hot it is overweight can not excrete, promote to be extended down to whelk, the acne, toothache, swelling and aching of gum, inflamed eyes, hypertension, sty of induction after " part of the body cavity above the diaphragm housing the heart and lungs " cardiopulmonary on the fire of the taste of internal " middle coke ".Formula are as follows: the coptis, rheum officinale, smilax, Asian puccoon, Java brucea, gleditsia sinensis, Chinese prickly ash, the root of Dahurain angelica, the achene of Siberian cocklebur, the flower bud of lily magnolia, folium artemisiae argyi, evodia rutaecarpa, Radix Angelicae Pubescentis, Liushen Pills, edible dried thin mushroom powder, edible flour soda, vinegar, Terbinafine, metronidazole, antipyrino-caffeinum citricum, YUJIN YINXIE PIAN, methenamine piece.

Description

A kind of compound preparation for treating multiple dermatosis
Technical field
The present invention relates to medicine and pharmacology technical field, specifically a kind of compound preparation for treating skin dermatomycosis.
Background technique
Fungal dermatopathy, also known as dermatomycosis refer to the human skin as caused by disease fungus and mucous membrane, hair One major class infectious diseases of hair and first-class cutaneous appendages.Dermatophyte is the main pathogenic bacteria of fungal dermatopathy, is had red Color trichophyta, trichophyton gypseum, acrothesium floccosum, Trichophyton verrucosum, Microsporum canis etc..The common feature of such disease Be: disease incidence is high, has infectiousness, is easy to recur or infect again.It is especially unreasonable, it is nonstandard treatment will cause recurrent exerbation, It treats repeatedly, the quality of life of strong influence patient.Fungi likes warm moist, and the optimum temperature of superficial mycosis is 22 DEG C ~28 DEG C.When there is the condition of suitable fungi growth and breeding on human skin, it is easy for that tinea disease occurs.As some people are easy Sweat, skin are easy humidity, such as clean and keep not in time drying, is easy infection fungi and the tinea such as tinea versicolor disease occurs;Worn trousers The sub- blocked up airtight, long-time of tension sits office, is easy to suffer from the tinea such as jock itch disease;Rubber overshoes, leather shoes, sport footwear are often worn, such as thoroughly Gas is poor, and the humidity and temperature of foot increase, if the tinea such as tinea pedis disease just easily occurs along with skin is not clean.Moreover, body On if there is a kind of tinea disease, can also make other positions that tinea disease also occur by own propagation.
However it is many for dermatomycosis curative drug at present, majority is the skin care item of some skin cares, such as: Glycerol or other be the cold cream of skin moisturizing, therapeutic effect be also all it is general, slow effect, some chemical components contain sharp Plain class drug, is easy recurrence after healing, therefore a kind of market significant, quick, without side-effects, the nothing that also needs to study therapeutic effect Stimulation, what is do not recurred is a kind of for treating the compound preparation of dermatomycosis.
Summary of the invention
Technical problem to be solved by the present invention lies in provide that a kind of formula is simple, manufacture craft is easy, toxic side effect Small and convenient drug administration, medicament is easily fabricated, low-cost new drug.The present invention is compound preparation, and product can play removing toxic substances and dispel Itch, dehumidifying wind-dispelling, the effect for eliminating the various color spots of skin, moisturizing analgesic.Skin can be treated to be invaded by perverse trends such as " chill are wet " Eczema, nettle rash, acne rosacea, rhinitis, verruca plana, whole body itch, monkey, tinea pedis, psoriasis, the leucoderma, mosquito occurred afterwards The disease of sufferings caused by biting and because in vivo it is damp and hot it is overweight can not excrete, promote to prolong on the fire of the taste of internal " middle coke " Whelk, acne, toothache, swelling and aching of gum, inflamed eyes, hypertension, the sty induced after to " part of the body cavity above the diaphragm housing the heart and lungs " cardiopulmonary all has Good effect.The present invention uses the medicinal material of different properties, has carried out scientific compatibility, can reach ideal therapeutic effect, and pacify Entirely, toxic side effect is small, and preparation is simple, and can go directly lesion, and healing time is short, controls difficulty in relapse after healing.
In order to solve the above technical problems, the present invention provides and a kind of treats Chinese materia medica preparation described in the compound preparation of multiple dermatosis In various bulk pharmaceutical chemicals weight fraction ratio are as follows:
25-30 parts of the coptis, 16-20 parts of rheum officinale, 20-22 parts of smilax, 15-22 parts of Asian puccoon, 14-16 parts of Java brucea, gleditsia sinensis 10-15 parts, 12-20 parts of Chinese prickly ash, 10-15 parts of the root of Dahurain angelica, 16-20 parts of the achene of Siberian cocklebur, 1-10 parts of the flower bud of lily magnolia, 12-16 parts of folium artemisiae argyi, evodia rutaecarpa 25-30 parts, 25-30 parts of Radix Angelicae Pubescentis, 1-10 parts of Liushen Pills, edible 12-16 parts of dried thin mushroom powder, 45-55 parts of edible flour soda, vinegar 1000-1500 parts, 1-10 parts of Terbinafine, 1-10 parts of metronidazole, 1-15 parts of antipyrino-caffeinum citricum, 1-15 parts of YUJIN YINXIE PIAN, Wu Luo 1-6 parts of tropine piece;
A kind of compound preparation for treating multiple dermatosis, the weight fraction ratio of various bulk pharmaceutical chemicals are optimal are as follows:
It is 30 parts of the coptis, 20 parts of rheum officinale, 20 parts of smilax, 15 parts of Asian puccoon, 15 parts of Java brucea, 15 parts of gleditsia sinensis, 20 parts of Chinese prickly ash, white 15 parts of the root of Dahurian angelica, 20 parts of the achene of Siberian cocklebur, 10 parts of the flower bud of lily magnolia, 15 parts of folium artemisiae argyi, 30 parts of evodia rutaecarpa, 30 parts of Radix Angelicae Pubescentis, 10 parts of Liushen Pills, edible dried thin mushroom 15 parts of powder, 50 parts of edible flour soda, 1500 parts of vinegar, 10 parts of Terbinafine, 10 parts of metronidazole, 15 parts of antipyrino-caffeinum citricum, Radix Curcumae 15 parts of silver-colored chip, 6 parts of methenamine piece;
In order to solve the above technical problems, the present invention provides a kind of preparation method of compound preparation for treating multiple dermatosis, The preparation is that the preparation method of liquid dosage form includes:
Preparation method: the coptis, rheum officinale, smilax, Asian puccoon, Java brucea, gleditsia sinensis, Chinese prickly ash, the root of Dahurain angelica, Siberian cocklebur are taken by formula rate Son, the flower bud of lily magnolia, folium artemisiae argyi, evodia rutaecarpa, Radix Angelicae Pubescentis pick be added after net dissection residual drug immerse in vinegar impregnates 7-15 days filter after abandon Slag stays liquid, smears affected part.
In order to solve the above technical problems, the present invention provides a kind of preparation method of compound preparation for treating multiple dermatosis, The preparation is that the preparation method of plaster dosage form includes:
Preparation method:
Powder is broken into after proportionally preparing each raw material by formula rate be tuned into paste with vinegar be attached to skin affected part ?.
Chinese medicine effect with the following functions of the present invention:
The coptis has the effect of purging fire for removing toxin, heat-clearing and damp-drying drug.
Rheum officinale has the effect of expelling the heat-evil, removing pattogenic heat from the blood and toxic material from the body, dispelling stasis of blood and stimulating the menstrual flow, downlink of igniting.
The effect of smilax has heat-clearing, dispels damp and hot sore.
Asian puccoon has the effect of cool blood, promoting blood circulation, promoting eruption of detoxifying.
Java brucea has clearing heat and detoxicating effect.
Gleditsia sinensis has the effect of searching wind, detoxification, detumescence and apocenosis.
Chinese prickly ash has the effect of warming spleen and stomach for dispelling cold, damp dispelling and pain relieving, relieve stagnation.
The effect of root of Dahurain angelica dehumidifies with relieve heat, sensible analgesic, detumescence and apocenosis.
The achene of Siberian cocklebur has effects that treat rhinitis chronic, allergic rhinitis.It is smeared after decoction in vitro to golden yellow Staphylococcus and skin ulcer have good bacteriostasis efficacy.
The flower bud of lily magnolia has the effect of expelling cold, eliminating, clearing the nasal passage.
Folium artemisiae argyi has the effect of eliminating cold to stop pain, warming channel for arresting bleeding.
Evodia rutaecarpa has effects that heat dissipation analgesic.
Radix Angelicae Pubescentis has the effect of dispelling wind and eliminating dampness, eliminating cold to stop pain.For caused few the moon volt wind headache after under the weather arthritis with fixed pain caused by dampness And toothache.
Liushen Pills has the effect of refreshing and detoxicating, anti-inflammatory analgetic.External application can be used for treating children's furuncle, large carbuncle furunculosis, tooth Bitterly, nameless gall.Medical evidence finds the medicine to treatment prickly heat in recent years, and toothache has fabulous curative effect with eczema.
Edible Xianggu-mushroom has beautifying face and moistering lotion, promotes blood circulation, dispels and inhibits melanin growth, nourishes skin, enhancing The effect of Abwehrkraft des Koepers.
Edible flour soda has the effect of antipruritic, clearing damp heat, removing toxic substances.
Vinegar has the effect of desinsection, sterilization.
Terbinafine external application, which has, treats various superficial mycoses, such as: tinea of feet and hands, ringworm of the body, favus of the scalp, jock itch and first are true Bacterium disease, infection by dematiaceous fungi, dermatophyte have fine effect.
Metronidazole external application has treatment trichomoniasis, balantidiasis and cutaneous Leishmaniasis, Infection by Dracunculus medinensis Deng, be also widely used in the treatment of anaerobic infection at present.
External application has the pain process of inhibition for reinforcing skin surface after antipyrino-caffeinum citricum and other medicines cooperation, also has relieving convulsion Analgesic, antipruritic effect.
YUJIN YINXIE PIAN has the promoting flow of qi and blood, and softening hardness to remove stagnation of food is clearing heat and detoxicating, and removing dampness and destroying parasites improves blood circulation quality, increases The immunity and resistance of strong skin, YUJIN YINXIE PIAN external application and other medicines matching can treat the skin diseases such as psoriasis, it has There is the promoting flow of qi and blood, softening hardness to remove stagnation of food is clearing heat and detoxicating, removing dampness and destroying parasites, the immunity and resistance that improve blood circulation quality, enhance skin Power.
Methenamine external application can treat various tinea diseases, tinea pedis, underarm odor etc..
Specific embodiment:
Embodiment 1, formula: coptis 25g, rheum officinale 16g, smilax 20g, Asian puccoon 15g, Java brucea 14g, gleditsia sinensis 10g, Chinese prickly ash 12g, root of Dahurain angelica 10g, achene of Siberian cocklebur 16g, flower bud of lily magnolia 1g, folium artemisiae argyi 12g, evodia rutaecarpa 25g, Radix Angelicae Pubescentis 25g, Liushen Pills 1g, edible dried thin mushroom powder Last 12g, edible flour soda 45g, vinegar 1000g, Terbinafine 1g, metronidazole 1g, antipyrino-caffeinum citricum 1g, YUJIN YINXIE PIAN 1g, crow Lip river tropine piece 1g;
Preparation method:
Powder is broken into after proportionally preparing each raw material by formula rate be tuned into paste with vinegar be attached to skin affected part ?.
Embodiment 2, formula: coptis 30g, rheum officinale 20g, smilax 20g, Asian puccoon 15g, Java brucea 15g, gleditsia sinensis 15g, Chinese prickly ash 20g, root of Dahurain angelica 15g, achene of Siberian cocklebur 20g, flower bud of lily magnolia 10g, folium artemisiae argyi 15g, evodia rutaecarpa 30g, Radix Angelicae Pubescentis 30g, Liushen Pills 10g, edible dried thin mushroom Powder 15g, edible flour soda 50g, vinegar 1500g, Terbinafine 10g, metronidazole 10g, antipyrino-caffeinum citricum 15g, YUJIN YINXIE PIAN 15g, methenamine piece 6g;
Preparation method: the coptis, rheum officinale, smilax, Asian puccoon, Java brucea, gleditsia sinensis, Chinese prickly ash, the root of Dahurain angelica, Siberian cocklebur are taken by formula rate Son, the flower bud of lily magnolia, folium artemisiae argyi, evodia rutaecarpa, Radix Angelicae Pubescentis pick be added after net dissection residual drug immerse in vinegar impregnates 7-15 days filter after abandon Slag stays liquid, smears affected part.
Embodiment 3, formula:
Coptis 30g, rheum officinale 20g, smilax 22g, Asian puccoon 22g, Java brucea 16g, gleditsia sinensis 15g, Chinese prickly ash 20g, root of Dahurain angelica 15g, Achene of Siberian cocklebur 20g, it flower bud of lily magnolia 10g, folium artemisiae argyi 16g, evodia rutaecarpa 30g, Radix Angelicae Pubescentis 30g, Liushen Pills 10g, edible dried thin mushroom powder 16g, eats Face alkali 55g, vinegar 1500g, Terbinafine 10g, metronidazole 10g, antipyrino-caffeinum citricum 15g, YUJIN YINXIE PIAN 15g, methenamine Piece 6g;
Preparation method is same as Example 1.
Embodiment 4, formula:
By rheum officinale 20g, achene of Siberian cocklebur 20g, flower bud of lily magnolia 10g, edible dried thin mushroom powder 16g, folium artemisiae argyi 16g just use this 5 taste medicine according to Ratio breaks into after powder jointly and is tuned into paste outer patch " ophryon point, Jingming acupoint, point bl 2, fragrant cave, the cave Tong Gu, connected valleys with sesame oil Cave " either directly sesame oil be placed in pot refining open the above 5 taste medicine is poured into oil cauldron again pharmacological property is blasted filtering after use oil juice Being applied on gauze more than outer patch 6 acupuncture points has remarkable result to treatment rhinitis.
Embodiment 5, formula:
Root of Dahurain angelica 15g, Liushen Pills 10g, evodia rutaecarpa 30g, Radix Angelicae Pubescentis 30g, rheum officinale 20g are proportionally added after common powder edible Vinegar is tuned into paste in right amount and has embrocated whelk, and the affected part of acne can also add " yellow simply on the basis of the above 5 taste medicine Even 20g " proportionally common powder, the fire for drawing the part of the body cavity above the diaphragm housing the heart and lungs can be played by being tuned into paste with vinegar and being placed directly against in " Yongquan acupoint " of sole The effect of downlink, so to treatment whelk, acne, acute toothache, swelling and aching of gum, inflamed eyes, blood pressure lowering, sty all have There is extraordinary curative effect.Through clinical experiments have proved that its cure rate can reach 95% or more.
All above-mentioned this intellectual properties of primarily implementation, there is no this new products of implementation of setting limitation other forms And/or new method.Those skilled in the art will utilize this important information, above content modification, to realize similar execution feelings Condition.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above described is only a preferred embodiment of the present invention, being not that the invention has other forms of limitations, appoint What those skilled in the art changed or be modified as possibly also with the technology contents of the disclosure above equivalent variations etc. Imitate embodiment.But without departing from the technical solutions of the present invention, according to the technical essence of the invention to above embodiments institute Any simple modification, equivalent variations and the remodeling made, still fall within the protection scope of technical solution of the present invention.

Claims (4)

1. a kind of compound preparation for treating multiple dermatosis, which is characterized in that the weight of various bulk pharmaceutical chemicals in the Chinese materia medica preparation Portion rate are as follows:
25-30 parts of the coptis, 16-20 parts of rheum officinale, 20-22 parts of smilax, 15-22 parts of Asian puccoon, 14-16 parts of Java brucea, gleditsia sinensis 10-15 Part, 12-20 parts of Chinese prickly ash, 10-15 parts of the root of Dahurain angelica, 16-20 parts of the achene of Siberian cocklebur, 1-10 parts of the flower bud of lily magnolia, 12-16 parts of folium artemisiae argyi, evodia rutaecarpa 25-30 Part, 25-30 parts of Radix Angelicae Pubescentis, 1-10 parts of Liushen Pills, edible 12-16 parts of dried thin mushroom powder, 45-55 parts of edible flour soda, vinegar 1000- 1500 parts, 1-10 parts of Terbinafine, 1-10 parts of metronidazole, 1-15 parts of antipyrino-caffeinum citricum, 1-15 parts of YUJIN YINXIE PIAN, methenamine piece 1-6 parts.
2. a kind of compound preparation for treating multiple dermatosis according to claim 1, which is characterized in that various bulk pharmaceutical chemicals Weight fraction ratio is optimal are as follows:
30 parts of the coptis, 20 parts of rheum officinale, 20 parts of smilax, 15 parts of Asian puccoon, 15 parts of Java brucea, 15 parts of gleditsia sinensis, 20 parts of Chinese prickly ash, the root of Dahurain angelica 15 Part, 20 parts of the achene of Siberian cocklebur, 10 parts of the flower bud of lily magnolia, 15 parts of folium artemisiae argyi, 30 parts of evodia rutaecarpa, 30 parts of Radix Angelicae Pubescentis, 10 parts of Liushen Pills, edible dried thin mushroom powder 15 parts, 50 parts of edible flour soda, 1500 parts of vinegar, 10 parts of Terbinafine, 10 parts of metronidazole, 15 parts of antipyrino-caffeinum citricum, Radix Curcumae silver bits 15 parts of piece, 6 parts of methenamine piece.
3. a kind of preparation method of compound preparation for treating multiple dermatosis according to any one of claims 1 or 2, Be characterized in that: the preparation is that the preparation method of liquid dosage form includes:
Preparation method: by formula rate take the coptis, rheum officinale, smilax, Asian puccoon, Java brucea, gleditsia sinensis, Chinese prickly ash, the root of Dahurain angelica, the achene of Siberian cocklebur, The flower bud of lily magnolia, folium artemisiae argyi, evodia rutaecarpa, Radix Angelicae Pubescentis pick be added after net dissection residual drug immerse in vinegar impregnates 7-15 days filter after waste stay Liquid smears affected part.
4. a kind of preparation method of compound preparation for treating multiple dermatosis according to any one of claims 1 or 2, Be characterized in that: the preparation is that the preparation method of plaster dosage form includes:
Preparation method:
Powder is broken into after proportionally preparing each raw material by formula rate be tuned into paste with vinegar be attached to skin affected part.
CN201710376245.8A 2017-05-25 2017-05-25 A kind of compound preparation for treating multiple dermatosis Pending CN108938997A (en)

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Publication number Priority date Publication date Assignee Title
CN101357190A (en) * 2008-09-16 2009-02-04 张传华 Traditional Chinese medicine composition for treating skin disease and preparation method thereof
CN103705883A (en) * 2013-12-17 2014-04-09 陈中元 Medicine for treating skin diseases and preparation
CN103977318A (en) * 2014-06-04 2014-08-13 罗小净 Liniment of traditional Chinese medicine composition for treating skin disease and preparation method thereof
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