CN108938794A - 一种驱风止痛的外用剂及其制备方法 - Google Patents
一种驱风止痛的外用剂及其制备方法 Download PDFInfo
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Abstract
本发明公开一种驱风止痛的外用剂及其制备方法,其成分由重量比薄荷脑5‑20%、樟脑5‑20%、冰片1‑3%、丁香油0.1‑1%、桂叶油1‑3%、肉桂油0.1‑1%、薄荷油0.1‑1%、白油20‑50%、当归1‑5%、木香1‑5%、广藿香1‑5%、甘草1‑5%、八角茴香1‑5%、肉桂1‑5%、陈皮1‑5%、栀子1‑5%、川芎1‑5%、马兰草1‑5%组成,并依次取原料,搅拌溶解完全后出料,可达到驱风止痛的效果。
Description
技术领域
本发明涉及中药领域,具体涉及一种驱风止痛的外用剂及其制备方法。
背景技术
人们经常出现的头晕头痛,腰酸背痛,风火牙痛,风湿骨痛,蚊虫叮咬等症状,都离不开使用驱风止痛的药物来施治,西药治疗常常会因药物的毒副作用而受损,中药通常需要长时间的熬制,费时间费精力,因此,患者急需一种副作用小、服用方便的药物。
发明内容
基于此,有必要针对以上提出的缺点,提供一种驱风止痛的外用剂及其制备方法。
一种驱风止痛的外用剂,其成分由以下重量比组成:薄荷脑5-20%、樟脑5-20%、冰片1-3%、丁香油0.1-1%、桂叶油1-3%、肉桂油0.1-1%、薄荷油0.1-1%、白油20-50%、当归1-5%、木香1-5%、广藿香1-5%、甘草1-5%、八角茴香1-5%、肉桂1-5%、陈皮1-5%、栀子1-5%、川芎1-5%、马兰草1-5%。
进一步地,一种驱风止痛的外用剂,其成分由以下重量比组成:薄荷脑10%、樟脑11%、冰片1%、丁香油0.7%、桂叶油3%、肉桂油0.8%、薄荷油0.7%、白油37.8%、当归4%、木香4%、广藿香4%、甘草2%、八角茴香4%、肉桂5%、陈皮2%、栀子4%、川芎4%、马兰草2%。
一种驱风止痛的外用剂及其制备方法,其包括上述的组合物外,其制备方法由以下步骤完成:
(1)取配方量的当归、木香、广藿香、甘草、八角茴香、肉桂进行粉碎,过40-60目筛,混合得到干粉;向干粉中加入其质量10倍的水,于100℃下煎煮3次,每次1h,将上述提取3次的提取液合并;将合并后的提取液在60-70℃下减压浓缩,得浓缩提取液,再经过喷雾干燥,得A品;
(2)取配方量的陈皮、栀子、川芎、马兰草进行粉碎,过90目筛,混合得到干粉;向干粉中加入其质量12倍的水,于80℃下煎煮3次,每次1h,将上述提取2次的提取液合并;将合并后的提取液在60-70℃下减压浓缩,得浓缩提取液,再经过喷雾干燥,得B品;
(3)加入白油到搅拌锅,将搅拌锅升温到80℃,加入A品和B品,搅拌1小时,速度为25/min,冷却搅拌锅,待搅拌锅降温至42℃,加入薄荷脑,樟脑,冰片,丁香油,桂叶油,肉桂油,薄荷油,搅拌,搅拌速度为30转/min,保温20min,得药剂;
(4)取半成品送检,检验合格后出料,出料后装瓶成成品。
薄荷脑:一种化学药剂,薄荷脑系由薄荷的叶和茎中所提取,白色晶体,为薄荷和欧薄荷精油中的主要成分,薄荷脑和消旋薄荷脑均可用作牙膏;香水;饮料和糖果等的赋香剂。在医药上用作刺激药,作用于皮肤或粘膜,有清凉止痒作用;内服可作为驱风药,用于头痛及鼻;咽;喉炎症等。其酯用于香料和药物。
樟脑:樟脑为樟科植物樟的枝、干、叶及根部, 经提炼制得的颗粒状结晶。樟脑具有通关窍、利滞气、辟秽浊、杀虫止痒、驱风止痛的功效,主治疥癣瘙痒、跌打伤痛、牙痛等症状。
冰片:龙脑、龙脑香、脑子、冰片、片脑、冰片脑、梅花脑、天然冰片、老梅片、梅片。主要成分:本品为从龙脑香的树脂和挥发油中取得的结晶,是近乎纯粹的右旋龙脑。龙脑香的树脂和挥发油中含有多种萜类成分。冰片为龙脑香科植物龙脑香的加工品,其成分含右旋龙脑律草烯、β-榄香烯、石竹烯等。本品味辛,性寒,有通诸窍、散郁火,消肿去翳等作用。在美容方中以之作清热散火、辟秽化浊之品,用于因血热,内热蕴结所致的口臭、体气、疮疡肿疖等症的治疗。
丁香油:为桃金娘科植物丁香的干燥花蕾经蒸馏所得的挥发油。暖胃,温肾。主治胃寒痛胀、呃逆、吐泻、痹痛,疝痛,口臭,牙痛。
肉桂油:以用于饲料,食品,香料,外用药等领域!芳香健胃,驱风。外用:治风湿及皮肤瘙痒。
薄荷油:薄荷油为无色或淡黄色的澄清液体。有特殊清凉香气,味初辛、后凉。存放日久,色渐变深。常被用于驱赶蚊虫,缓解身体疲劳。
白油:适用于化妆工业,可作发乳、发油、唇膏、面油、护肤油、防晒油、婴儿油、雪花膏等软膏和软化剂的基础油。
桂叶油:主要是芳香健胃,祛风,祛寒,通脉,止痛,也具补阳温肾之效。也有用在调配香精或其他精细化工产品之用途。
当归:甘,温,无毒;功能主治补血;活血;调经止痛;润燥滑肠。主血虚诸证;***;经闭;痛经;症瘕结聚;崩漏;虚寒腹痛;痿痹;肌肤麻木;肠燥便难;赤痢后重;痈疽疮疡;跌扑损伤。
木香:性味辛、苦,温,行气止痛,调中宣滞,用于脘腹胀痛,泻痢后重,脾虚食少,胁痛,黄疸。
广藿香:味辛,性微温;芳香化湿;和胃止呕;祛暑解表。主湿阻中焦之脘腹痞闵;食欲不振;呕吐;泄泻;外感暑湿之寒热头痛;湿温初起的发热身困;胸闵恶心;鼻渊;手足癣。
甘草:甘,平,无毒;功能主治清热解毒、祛痰止咳、脘腹等。
八角茴香:正名为八角,八角茴香的果实主治寒疝腹痛、腰膝冷痛、胃寒呕吐、脘腹疼痛、寒湿脚气等。对于治疗小肠气坠、疝气偏坠、腰重刺胀、腰病如刺、大小便皆秘,腹胀如鼓,气促、风毒湿气,攻疰成疮,皮肉紫破脓坏,行步无力,皮肉燥热等有显著效果。
肉桂:补元阳,暖脾胃,除积冷,通血脉。治命门火衰,肢冷脉微,亡阳虚脱,腹痛泄泻,寒疝奔豚,腰膝冷痛,经闭症瘕,阴疽,流注,及虚阳浮越,上热下寒。
陈皮:又称橘皮,辛散通温,气味芳香,长于理气,能入脾肺,故既能行散肺气壅遏,又能行气宽中,用于肺气拥滞、胸膈痞满及脾胃气滞、脘腹胀满等症;苦温燥湿而能健脾行气,故常用于湿阻中焦、脘腹胀闷、便溏苔腻等症,又能和中,可治胃失和降、恶心呕吐,若胃寒呕吐。
栀子:具有护肝、利胆、降压、镇静、止血、消肿等作用;在中医临床常用于治疗黄疸型肝炎、扭挫伤 、高血压、糖尿病等症。含番红花色素苷基,可作黄色染料。
川芎:是一种中药植物,常用于活血行气,祛风止痛,川芎辛温香燥,走而不守,既能行散,上行可达巅顶;又入血分,下行可达血海。活血祛瘀作用广泛,适宜瘀血阻滞各种病症;祛风止痛,效用甚佳,可治头风头痛、风湿痹痛等症。昔人谓川芎为血中之气药,殆言其寓辛散、解郁、通达、止痛等功能。
马兰草:马兰草的功效与作用就是有效地驱风止痛,作为中草药中的疗效药,马兰草的功效与作用远不止如此,马兰草功能主治:马兰草破宿血,养新血,止鼻衄吐血,合金疮,断血痢,解酒疸及诸菌毒、蛊毒。
本发明的用法与用量:外用,将适量的药液涂于患处。
具体实施方式
下面结合具体实施例对本发明做进一步详细地描述。
实施例1
一种驱风止痛的外用剂,其成分由以下重量比组成:薄荷脑8%、樟脑10%、冰片1%、丁香油0.8%、桂叶油3.5%、肉桂油0.7%、薄荷油0.5%、白油44.5%、当归3%、木香2%、广藿香4%、甘草4%、八角茴香3%、肉桂4%、陈皮3%、栀子2%、川芎2%、马兰草4%。
一种实施例中,一种驱风止痛的外用剂及其制备方法,其制备方法由以下步骤完成:
(1)取配方量的当归、木香、广藿香、甘草、八角茴香、肉桂进行粉碎,过40-60目筛,混合得到干粉;向干粉中加入其质量10倍的水,于100℃下煎煮3次,每次1h,将上述提取3次的提取液合并;将合并后的提取液在60-70℃下减压浓缩,得浓缩提取液,再经过喷雾干燥,得A品;
(2)取配方量的陈皮、栀子、川芎、马兰草进行粉碎,过90目筛,混合得到干粉;向干粉中加入其质量12倍的水,于80℃下煎煮3次,每次1h,将上述提取2次的提取液合并;将合并后的提取液在60-70℃下减压浓缩,得浓缩提取液,再经过喷雾干燥,得B品;
(3)加入白油到搅拌锅,将搅拌锅升温到80℃,加入A品和B品,搅拌1小时,速度为25/min,冷却搅拌锅,待搅拌锅降温至42℃,加入薄荷脑,樟脑,冰片,丁香油,桂叶油,肉桂油,薄荷油,搅拌,搅拌速度为30转/min,保温20min,得药剂;
(4)取半成品送检,检验合格后出料,出料后装瓶成成品。
实施例2
一种驱风止痛的外用剂,其成分由以下重量比组成:薄荷脑10%、樟脑11%、冰片1%、丁香油0.7%、桂叶油3%、肉桂油0.8%、薄荷油0.7%、白油37.8%、当归4%、木香4%、广藿香4%、甘草2%、八角茴香4%、肉桂5%、陈皮2%、栀子4%、川芎4%、马兰草2%。
其制备方法与实施例1相同。
实施例3
一种驱风止痛的外用剂,其成分由以下重量比组成:薄荷脑11%、樟脑9%、冰片1%、丁香油0.8%、桂叶油2%、肉桂油0.9%、薄荷油0.4%、白油35.9%、当归5%、木香4%、广藿香5%、甘草2%、八角茴香4%、肉桂4%、陈皮3%、栀子4%、川芎4%、马兰草4%。
其制备方法与实施例1相同。
以上所述实施例的各技术特征可以进行任意的组合,为使描述简洁,未对上述实施例中的各个技术特征所有可能的组合都进行描述,然而,只要这些技术特征的组合不存在矛盾,都应当认为是本说明书记载的范围。
以上所述实施例仅表达了本发明的几种实施方式,其描述较为具体和详细,但并不能因此而理解为对发明专利范围的限制。应当指出的是,对于本领域的普通技术人员来说,在不脱离本发明构思的前提下,还可以做出若干变形和改进,这些都属于本发明的保护范围。因此,本发明专利的保护范围应以所附权利要求为准。
Claims (3)
1.一种驱风止痛的外用剂,其特征在于,其成分由以下重量比组成:薄荷脑5-20%、樟脑5-20%、冰片1-3%、丁香油0.1-1%、桂叶油1-3%、肉桂油0.1-1%、薄荷油0.1-1%、白油20-50%、当归1-5%、木香1-5%、广藿香1-5%、甘草1-5%、八角茴香1-5%、肉桂1-5%、陈皮1-5%、栀子1-5%、川芎1-5%、马兰草1-5%。
2.根据权利要求1所述的外用剂,其特征在于,其成分由以下重量比组成:薄荷脑10%、樟脑11%、冰片1%、丁香油0.7%、桂叶油3%、肉桂油0.8%、薄荷油0.7%、白油37.8%、当归4%、木香4%、广藿香4%、甘草2%、八角茴香4%、肉桂5%、陈皮2%、栀子4%、川芎4%、马兰草2%。
3.根据权利要求2所述的外用剂及其制备方法,其特征在于,所述的制备方法由以下步骤完成:
(1)取配方量的当归、木香、广藿香、甘草、八角茴香、肉桂进行粉碎,过40-60目筛,混合得到干粉;向干粉中加入其质量10倍的水,于100℃下煎煮3次,每次1h,将上述提取3次的提取液合并;将合并后的提取液在60-70℃下减压浓缩,得浓缩提取液,再经过喷雾干燥,得A品;
(2)取配方量的陈皮、栀子、川芎、马兰草进行粉碎,过90目筛,混合得到干粉;向干粉中加入其质量12倍的水,于80℃下煎煮3次,每次1h,将上述提取2次的提取液合并;将合并后的提取液在60-70℃下减压浓缩,得浓缩提取液,再经过喷雾干燥,得B品;
(3)加入白油到搅拌锅,将搅拌锅升温到80℃,加入A品和B品,搅拌1小时,速度为25/min,冷却搅拌锅,待搅拌锅降温至42℃,加入薄荷脑,樟脑,冰片,丁香油,桂叶油,肉桂油,薄荷油,搅拌,搅拌速度为30转/min,保温20min,得药剂;
(4)取半成品送检,检验合格后出料,出料后装瓶成成品。
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