CN108852847A - A kind of micro- package instrument of drug and its system - Google Patents
A kind of micro- package instrument of drug and its system Download PDFInfo
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- CN108852847A CN108852847A CN201810869781.6A CN201810869781A CN108852847A CN 108852847 A CN108852847 A CN 108852847A CN 201810869781 A CN201810869781 A CN 201810869781A CN 108852847 A CN108852847 A CN 108852847A
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- micro
- internal box
- needle tubing
- governor
- injection pump
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/005—Coating of tablets or the like
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The invention discloses a kind of micro- package instrument of drug and its systems, are related to pharmaceutical equipment technical field.The present invention includes workbench body, the first micro-injection pump and the second micro-injection pump；One surface of workbench body is fixed with air pump and outer case；Outer case inner surface is installed with internal box by fixed block；Air pump outlet side inside appendix and internal box by being connected；Internal box lower surface offers a through hole being connected with inner cavity；The fixation of internal box top is interspersed with an outer needle tubing；Outer needle tubing lower end extends to inside internal box and is right against through hole；Fixation is interspersed with an inner needle tube in outer needle tubing.The present invention is by being based on capillary flow phenomenon, setting is matched using inner needle tube and outer needle tubing, composite conic is formed in inner needle tube and outer needle tubing lower end and generates compound jet, microlayer model is broken by means of the unstability in compound jet, to realize the package to medical fluid, market popularization value with higher.
Description
Technical field
The invention belongs to pharmaceutical equipment technical fields, more particularly to a kind of micro- package instrument of drug and its system.
Background technique
Currently, the domestic dedicated dosage form of children's drug extremely lacks.The data provided according to the pharmaceutical sector chamber of commerce of the All-China Federation of Industry and Commerce are aobvious
Show, existing more than the 3500 a preparation variety of China, only 60 kinds of children special-purpose, ratio only accounts for 1.7%.Hospital can only " as one sees fit " with
Adult medication and dosage form replace children's drug.One statistics of State Food and Drug Administration shows the country 90%
Drug does not have children's dosage form.So-called children's medicine is often the decrement version of adult medicine.
For children's oral drugs, size, taste, the dose intensity etc. of dosage form are great challenges, and children swallow energy
The difference of power, taste preference, dose requirements etc. are but also oral drugs need different dosage forms.However, about 50% children
Drug does not have paediatric formats.The shelf-life of some liquid pediatric preparations under refrigerated conditions only has 3 months, shorter at room temperature,
Even over time, the activity of active drug ingredient can decline 45%.In addition, 50% or so 6-11 years old children gulp down
Pharyngea agent is difficult, and the bitterness sense of some clinic active drugs is difficult to cover by food or syrup, to be refused by child of tender age.
The technology that domestic market covers bitter taste use for children mainly adds corrigent method, fills drug
Microcapsules are coated tablet.Corrigent mainly includes sweetener, aromatic, effervescent agent and mucilage etc..Drug is covered in coating
Bitter taste art for coating is to wrap the clothing layer of appropriate materials on solid drugs surface, reaches preferable and covers bitter taste of drug and bad gas
The purpose of taste.In addition also useful micro-capsule or microballoon cover bitter taste of drug, micro-capsule, microballoon be in recent years medicinal application new process,
One protrusion of new technology represents.After medicament microcapsule, the bad smell of drug can be not only covered, and medicine can be improved
The stability of object, the effects of preventing drug from inactivating in stomach or reducing the irritation to stomach.
Currently, the drug particle size that existing drug wrapping device wraps up out is bigger, for children taking,
It is difficult to swallow bulky grain drug, this is problem bigger existing for current wrapping device.Therefore, needing to study one kind can will
The children's drug for covering bitter taste narrows down to the micro- wrapping device of drug for the size for enabling the imperceptible granular sensation of children, in order to solve
The above problem.
Summary of the invention
The purpose of the present invention is to provide a kind of micro- package instrument of drug and its systems, by being based on capillary flow phenomenon, benefit
Setting is matched with inner needle tube and outer needle tubing, in inner needle tube and outer needle tubing lower end composite conic and generates compound jet, is borrowed in multiple
Close the unstability of jet stream and be broken into microlayer model, solve existing drug due to the bitterness is excessive and be difficult to by food or
Syrup cover and cause child of tender age refusal take with existing drug wrapping device to drug particle size can not control ask
Topic.
In order to solve the above technical problems, the present invention is achieved by the following technical solutions：
The present invention is a kind of micro- package instrument of drug, including workbench body, is installed with the first micro note of the first syringe
It penetrates pump and is installed with the second micro-injection pump of the second syringe；First micro-injection pump and the second micro-injection pump are solid
Surely it is installed on one surface of workbench body；One surface of workbench body also fixation is installed with an air pump and an outer case；
The outer case inner surface is installed with an internal box by fixed block；The air pump outlet side passes through in an appendix and internal box
Portion is connected；The internal box lower surface offers a through hole being connected with inner cavity；The internal box top is fixed interspersed
There is an outer needle tubing；The outer needle tubing lower end extends to inside internal box and is right against through hole；It is fixed interspersed in the outer needle tubing
There is an inner needle tube；The first syringe outlet end is connected by one first perfusion tube with outer needle tubing upper end；Second note
Emitter outlet end is connected by one second perfusion tube with inner needle tube upper end.
Further, one surface of workbench body is fixed is installed with one for controlling the work of the first micro-injection pump
The second governor and one of the work speed of service of first governor of the speed of service, one for controlling the second micro-injection pump is used
In the third governor of the work speed of service of control air pump.
Further, one surface of workbench body is fixed is installed with one for controlling the work of the first micro-injection pump
Second touch screen of the first touch screen of state and a working condition for controlling the second micro-injection pump.
Further, one surface of workbench body is installed with a pressure display unit；The internal box inner surface is fixed
There is one to keep the pressure sensor being electrically connected with pressure display unit.
Further, outer needle tubing lower port is extended in the inner needle tube lower end, forms a difference in height；The length of the difference in height
Degree is between 1-5mm range；The overall diameter of the inner needle tube is less than the interior diameter of outer needle tubing.
A kind of control system of the micro- package instrument of drug, including microprocessor and DC power supply；The microprocessor passes through number
It is connected respectively with the first governor, the second governor and third governor according to transmission module；The microprocessor passes through data
Transmission module keeps the interaction of information with the first touch screen and the second touch screen respectively；The microprocessor transmits mould by data
Block carries out the transmission of data with pressure display unit and pressure sensor respectively；The DC power supply respectively with the first governor,
Two governors and third governor keep being electrically connected；The DC power supply by an electric pressure converter respectively with the first touch-control
Screen, the second touch screen and pressure display unit are electrically connected.
The invention has the advantages that：
The present invention keeps the first note by the way that air pump is arranged prior to the first micro-injection pump and the second micro-injection pump work
Emitter is identical with the liquid speed rate out of the second syringe, the outside needle tubing note of the first syringe being utilized respectively on the first micro-injection pump
In interior case when penetrating the second syringe on package liquid and the second micro-injection pump to inner needle tube liquid medicine injection, and being worked using air pump
Draught head is generated at the through hole of body, is based on capillary flow phenomenon, using swiftly flowing gas-powered, outer needle tubing and inner needle tube
In converge to form composite conic and generate compound jet with the target fluid of certain flow outflow, and projected from through hole, it is compound
Jet stream is because unstability is broken into microlayer model, to realize the package to medical fluid and taste masking, has uniform particle diameter, encapsulation ratio
The advantages such as high, yield height and applicability are wide, and the drop of size in this way is very suitable to children taking, avoids drug size
The excessive situation for being difficult to swallow.
Certainly, it implements any of the products of the present invention and does not necessarily require achieving all the advantages described above at the same time.
Detailed description of the invention
In order to illustrate the technical solution of the embodiments of the present invention more clearly, will be described below to embodiment required
Attached drawing is briefly described, it should be apparent that, drawings in the following description are only some embodiments of the invention, for ability
For the those of ordinary skill of domain, without creative efforts, it can also be obtained according to these attached drawings other attached
Figure.
Fig. 1 is the structural diagram of the present invention；
Fig. 2 is the structural front view of Fig. 1；
Fig. 3 is the structure top view of Fig. 1；
Fig. 4 is the structural schematic diagram of internal box of the invention；
Fig. 5 is system principle diagram of the invention.
In attached drawing, parts list represented by the reference numerals are as follows：
1- workbench body, the first micro-injection pump of 2-, the second micro-injection pump of 3-, 4- air pump, 5- outer case, case in 6-
Body, the outer needle tubing of 7-, 8- pressure display unit, the first syringe of 201-, the first perfusion tube of 202-, the first governor of 203-, 204- the
One touch screen, the second syringe of 301-, the second perfusion tube of 303-, the second governor of 303-, the second touch screen of 304-, 401- gas transmission
Pipe, 402- third governor, 501- fixed block, 601- through hole, 701- inner needle tube, 801- pressure sensor.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts all other
Embodiment shall fall within the protection scope of the present invention.
It please refers to shown in Fig. 1-4, the present invention is a kind of micro- package instrument of drug, including workbench body 1, the first syringe
201 the first micro-injection pump 2 and the second micro-injection pump 3 for being installed with the second syringe 301；First micro-injection pump, 2 He
Second micro-injection pump 3 is installed on 1 one surface of workbench body；The also fixation of 1 one surface of workbench body is installed with
One air pump 4 and an outer case 5；5 inner surface of outer case is installed with an internal box 6 by fixed block 501；4 outlet side of air pump passes through
It is connected inside one appendix 401 and internal box 6；6 lower surface of internal box offers a through hole 601 being connected with inner cavity；
The fixation of 6 top of internal box is interspersed with an outer needle tubing 7；Outer 7 lower end of needle tubing extends to 6 inside of internal box and is right against through hole 601；
Fixation is interspersed with an inner needle tube 701 in outer needle tubing 7；Outer 7 lower port of needle tubing is extended in 701 lower end of inner needle tube, forms a length and is
The difference in height of 2mm；The overall diameter of inner needle tube 701 is 1.1 times of the interior diameter of outer needle tubing 7；First syringe, 201 outlet end passes through
One first perfusion tube 202 is connected with outer 7 upper end of needle tubing；Second syringe, 301 outlet end by one second perfusion tube 303 with it is interior
701 upper end of needle tubing is connected.
It is worked by setting air pump 4 prior to the first micro-injection pump 2 and the second micro-injection pump 3, and keeps the first injection
Device 201 and the second syringe 301 go out that liquid speed rate is identical, be utilized respectively the first syringe 201 on the first micro-injection pump 2 to
The second syringe 301 on the outer injection of needle tubing 7 package liquid and the second micro-injection pump 3 is utilized to 701 liquid medicine injection of inner needle tube
Draught head is generated when air pump 4 works at the through hole 601 of internal box 6, capillary flow phenomenon is based on, utilizes swiftly flowing gas
Body drives, and converges to form composite conic and generate compound with the target fluid of certain flow outflow in outer needle tubing 7 and inner needle tube 701
Jet stream, and projected from through hole 601, compound jet is because unstability is broken into microlayer model, to realize the package to medical fluid.
Wherein as shown in Figure 1,1 one surface of workbench body is fixed to be installed with one for controlling the first micro-injection pump 2
First governor 203, one of the work speed of service is used to control the second speed regulation of the work speed of service of the second micro-injection pump 3
The third governor 402 of device 303 and the work speed of service for controlling air pump 4, it is micro to first to facilitate staff
The control of the work speed of service of syringe pump 2, the second micro-injection pump 3 and air pump 4, to ensure that the operation is stable of the equipment
Property.
Wherein as shown in Figure 1,1 one surface of workbench body is fixed to be installed with one for controlling the first micro-injection pump 2
Second touch screen 304 of the first touch screen 204 and a working condition for controlling the second micro-injection pump 3 of working condition,
Facilitate the setting of the control or operating parameter of start and stop of the staff to the first micro-injection pump 2 and the second micro-injection pump 3.
Wherein as shown in Figure 1 and Figure 4,1 one surface of workbench body is installed with a pressure display unit 8；6 inner surface of internal box
It is fixed with one and keeps the pressure sensor 801 being electrically connected with pressure display unit 8, facilitate staff and understand internal box in real time
6 pressure data；The model MPX5100A of pressure sensor 801, ensure that the accuracy of pressure measurement.
As shown in figure 5, a kind of control system of the micro- package instrument of drug, including microprocessor and DC power supply；Microprocessor
1 one surface of workbench body is installed on DC power supply；The model R7S910035 of microprocessor, ensure that data
The timeliness of processing；Microprocessor by data transmission module respectively with the first governor 203, the second governor 303 and third
Governor 402 is connected；Microprocessor is protected with the first touch screen 204 and the second touch screen 304 respectively by data transmission module
Hold the interaction of information；Microprocessor carries out data with pressure display unit 8 and pressure sensor 801 respectively by data transmission module
Transmission；DC power supply keeps being electrically connected with the first governor 203, the second governor 303 and third governor 402 respectively；
DC power supply is electrically connected with the first touch screen 204, the second touch screen 304 and pressure display unit 8 respectively by an electric pressure converter
It connects, the model SGM6019 of electric pressure converter ensure that voltage conversion efficiency.
Present invention disclosed above preferred embodiment is only intended to help to illustrate the present invention.There is no detailed for preferred embodiment
All details are described, are not limited the invention to the specific embodiments described.Obviously, according to the content of this specification,
It can make many modifications and variations.These embodiments are chosen and specifically described to this specification, is in order to better explain the present invention
Principle and practical application, so that skilled artisan be enable to better understand and utilize the present invention.The present invention is only
It is limited by claims and its full scope and equivalent.
Claims (6)
1. a kind of micro- package instrument of drug, including workbench body (1)；It is characterized in that：
It further include being installed with the first micro-injection pump (2) of the first syringe (201) and being installed with the of the second syringe (301)
Two micro-injection pumps (3)；First micro-injection pump (2) and the second micro-injection pump (3) are installed on the work playscript with stage directions
On (1) one surface of body；
(1) one surface of workbench body also fixation is installed with an air pump (4) and an outer case (5)；In the outer case (5)
Surface is installed with an internal box (6) by fixed block (501)；
Wherein, air pump (4) outlet side inside an appendix (401) and internal box (6) by being connected；
Internal box (6) lower surface offers a through hole (601) being connected with inner cavity；
Internal box (6) the top fixation is interspersed with an outer needle tubing (7)；Outer needle tubing (7) lower end extends in internal box (6)
Portion is simultaneously right against through hole (601)；Fixation is interspersed with an inner needle tube (701) in the outer needle tubing (7)；
Wherein, the first syringe (201) outlet end is connected by one first perfusion tube (202) with outer needle tubing (7) upper end；
Second syringe (301) outlet end is connected by one second perfusion tube (303) with inner needle tube (701) upper end.
2. the micro- package instrument of a kind of drug according to claim 1, which is characterized in that (1) one surface of workbench body
Fixed the first governor (203) for being installed with the work speed of service for controlling the first micro-injection pump (2), one are for controlling
The second governor (303) and one of the work speed of service of the second micro-injection pump (3) is made for controlling the work fortune of air pump (4)
The third governor (402) of scanning frequency degree.
3. the micro- package instrument of a kind of drug according to claim 1, which is characterized in that (1) one surface of workbench body
Fixed the first touch screen (204) and one for being installed with a working condition for controlling the first micro-injection pump (2) is for controlling
The second touch screen (304) of the working condition of second micro-injection pump (3).
4. the micro- package instrument of a kind of drug according to claim 1, which is characterized in that (1) one surface of workbench body
It is installed with a pressure display unit (8)；Internal box (6) inner surface is fixed with one and keeps being electrically connected with pressure display unit (8)
Pressure sensor (801).
5. the micro- package instrument of a kind of drug according to claim 1, which is characterized in that inner needle tube (701) lower end extends
Needle tubing (7) lower port out forms a difference in height；The length of the difference in height is between 1-5mm range；The inner needle tube
(701) overall diameter is less than the interior diameter of outer needle tubing (7).
6. a kind of control system of the micro- package instrument of drug as described in claim 1-5 any one, which is characterized in that including micro-
Processor and DC power supply；
The microprocessor by data transmission module respectively with the first governor (203), the second governor (303) and third tune
Fast device (402) is connected；The microprocessor by data transmission module respectively with the first touch screen (204) and the second touch screen
(304) interaction of information is kept；The microprocessor by data transmission module respectively with pressure display unit (8) and pressure sensing
The transmission of device (801) progress data；
The DC power supply keeps electricity with the first governor (203), the second governor (303) and third governor (402) respectively
Property connection；The DC power supply by an electric pressure converter respectively with the first touch screen (204), the second touch screen (304) and pressure
Power display (8) is electrically connected.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810869781.6A CN108852847A (en) | 2018-08-02 | 2018-08-02 | A kind of micro- package instrument of drug and its system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810869781.6A CN108852847A (en) | 2018-08-02 | 2018-08-02 | A kind of micro- package instrument of drug and its system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108852847A true CN108852847A (en) | 2018-11-23 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810869781.6A Pending CN108852847A (en) | 2018-08-02 | 2018-08-02 | A kind of micro- package instrument of drug and its system |
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| Country | Link |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999030834A1 (en) * | 1997-12-17 | 1999-06-24 | Universidad De Sevilla | Device and method for creating aerosols for drug delivery |
| CN101372463A (en) * | 2007-08-21 | 2009-02-25 | 宁波万华聚氨酯有限公司 | Draft tube type jet flow reactor and method for preparing isocyanate using the same |
| CN101837255A (en) * | 2009-03-17 | 2010-09-22 | 华东理工大学 | Method and device for preparing micro-bubbles |
| CN106924046A (en) * | 2017-04-24 | 2017-07-07 | 中国科学技术大学 | Medicine-carrying capsule prepares shower nozzle and medicine-carrying capsule preparation facilities |
| CN209286173U (en) * | 2018-08-02 | 2019-08-23 | 合肥中科力一科技有限公司 | A kind of micro- package instrument of drug and its system |
-
2018
- 2018-08-02 CN CN201810869781.6A patent/CN108852847A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999030834A1 (en) * | 1997-12-17 | 1999-06-24 | Universidad De Sevilla | Device and method for creating aerosols for drug delivery |
| CN101372463A (en) * | 2007-08-21 | 2009-02-25 | 宁波万华聚氨酯有限公司 | Draft tube type jet flow reactor and method for preparing isocyanate using the same |
| CN101837255A (en) * | 2009-03-17 | 2010-09-22 | 华东理工大学 | Method and device for preparing micro-bubbles |
| CN106924046A (en) * | 2017-04-24 | 2017-07-07 | 中国科学技术大学 | Medicine-carrying capsule prepares shower nozzle and medicine-carrying capsule preparation facilities |
| CN209286173U (en) * | 2018-08-02 | 2019-08-23 | 合肥中科力一科技有限公司 | A kind of micro- package instrument of drug and its system |
Non-Patent Citations (1)
| Title |
|---|
| 司廷;尹协振;: "流动聚焦研究进展及其应用", 科学通报, no. 08 * |
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