CN108837339A - flexible ultrasonic wave generating device - Google Patents
flexible ultrasonic wave generating device Download PDFInfo
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- CN108837339A CN108837339A CN201810720524.6A CN201810720524A CN108837339A CN 108837339 A CN108837339 A CN 108837339A CN 201810720524 A CN201810720524 A CN 201810720524A CN 108837339 A CN108837339 A CN 108837339A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
- A61B5/02055—Simultaneously evaluating both cardiovascular condition and temperature
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/024—Detecting, measuring or recording pulse rate or heart rate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/0816—Measuring devices for examining respiratory frequency
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0004—Applications of ultrasound therapy
- A61N2007/0021—Neural system treatment
- A61N2007/0026—Stimulation of nerve tissue
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Abstract
This disclosure relates to a kind of flexible ultrasonic wave generating device, including:Ultrasonic module, for emitting ultrasonic signal;Signal acquisition component, for obtaining the physiologic information signal of monitoring object;Control assembly, for generating first control signal according to the physiologic information signal, the first control signal is for controlling the ultrasonic module, so that the ultrasonic module emits ultrasonic signal;Flexible substrates, for carrying the ultrasonic module, the signal acquisition component and the control assembly.Flexible ultrasonic wave generating device according to an embodiment of the present disclosure, by flexible substrates come bearing ultrasonic component, signal acquisition component and control assembly, human body surface can be attached at, realize the noninvasive stimulation to carotid sinus, and it is adjusted according to signal characteristic of the physiologic information signal to ultrasonic wave, carotid sinus is accurately stimulated, to realize the accurate adjusting to physiological status.
Description
Technical field
This disclosure relates to technical field of medical detection more particularly to a kind of flexible ultrasonic wave generating device.
Background technique
Carotid sinus is that section is expanded in arteria carotis communis end and internal carotid starting point, there is sense abundant under tube wall outer membrane
Feel nerve endings, the effect of arterial blood tube wall mechanically stretching, thus also referred to as carotid sinus baroreceptor can be perceived.Neck is dynamic
It is the medically generally acknowledged important negative-feedback regu- lation mechanism for maintaining body blood pressure stabilization that arteries and veins sinus reflex, which is adjusted, when arterial pressure liter
Gao Shi, carotid sinus perceive the expansion tension of arterial blood tube wall, and sensory nerve ending discharges nerve impulse, nerve punching thereon
It is dynamic to reach tractus solitarius medullae oblongatae core from carotid sinus nerve by glossopharyngeal nerve as electronic signals, and then activate parasympathetic nerve
System inhibits stomodaeal nervous system, reduces the secretion of feritin and antidiuretic hormone, can be reflexive cause bradycardia, reduce
Blood volume and blood pressure.
The treatment of hypertension and heart failure medically remains the great difficult problem not yet captured, anti-according to carotid sinus
Penetrating property adjustment mechanism, carrying out electro photoluminescence to carotid sinus can be used to treat the diseases such as hypertension and heart failure, especially for some
Obstinate hypertension and heart failure etc., not only effect is unobvious but also has biggish toxic side effect for simple drug therapy.Currently,
There are preliminary achievement, but electro photoluminescence carotid sinus one about diseases such as carotid sinus electronic stimulation hypertension and heart failures
As need implant electrode of performing the operation, and be embedded to power supply and control system in vivo, thus there are the following problems:
(1) operation embedment medical device, is invasive treatment, there are certain risks.When the electrode and other accessories of implantation
It goes wrong, it is necessary to which replacement is taken out in operation again, brings great pain to patient.
(2) service life of power-supply system is shorter, in the service life of general only some months to 1 year, cannot achieve long-term stimulation, electricity
When the system charge deficiency of source, it is necessary to which replacement is taken out in operation again, brings great pain to patient.
(3) electrode being implanted into is more firm, larger with body tissue mechanical performance difference, has larger machinery to body tissue
Injury, so that nontarget area is arrived in stimulation, has in addition, being easy to produce leaky when the insulation effect of implant electrode is bad
Biggish side effect.
(4) for some patientss, carry out electro photoluminescence to carotid sinus baroreceptor can be realized preferably for a period of time
Therapeutic effect, it is still necessary to perform the operation to take out implant devices again, brings great pain to patient after treatment end.
(5) existing pressoreceptor electronic stimulation hypertension and heart failure are mostly open cycle system, can only carry out one direction
Adjusting, feedback adjusting can not be carried out according to body reaction, thus be unable to satisfy body itself to the essence of blood pressure and heart rate etc.
Really, it adjusts in real time.
Summary of the invention
In view of this, the present disclosure proposes a kind of flexible ultrasonic wave generating devices.
According to the one side of the disclosure, a kind of flexible ultrasonic wave generating device is provided, including:Ultrasonic module, signal
Securing component, control assembly and flexible substrates,
The ultrasonic module is for emitting ultrasonic signal;
The signal acquisition component is used to obtain the physiologic information signal of monitoring object;
The control assembly is used to generate first control signal, the first control signal according to the physiologic information signal
For controlling the ultrasonic module, so that the ultrasonic module emits ultrasonic signal;
The flexible substrates are for carrying the ultrasonic module, the signal acquisition component and the control assembly.
In one possible implementation, the control assembly generates the first control according to the physiologic information signal and believes
Number, including:
According to the physiologic information signal, the physiological parameter of the monitoring object is determined;
According to the physiological parameter of the monitoring object, the first signal characteristic corresponding with the physiological parameter is determined;
According to first signal characteristic, the first control signal is generated, so that ultrasonic module transmitting has
The ultrasonic signal of first signal characteristic.
In one possible implementation, the ultrasonic module is also used to receive the second of the monitoring object reflection
Ultrasonic signal, and acoustic-electric conversion is carried out to second ultrasonic signal, determine positioning signal,
The control assembly is also used to generate second control signal according to the positioning signal, and the second control signal is used
In controlling the ultrasonic module, so that the ultrasonic module transmitting focusing is in the ultrasonic signal of target area, wherein institute
It is associated with the position location of the positioning signal to state target area.
In one possible implementation, described device further includes parameter setting component, and the setting component is for connecing
Setting parameter is received, and generates setting signal corresponding with the setting parameter,
The control assembly is also used to generate third control signal according to the setting signal, and the third control signal is used
In controlling the ultrasonic module, so that ultrasonic module transmitting has the ultrasonic signal of second signal feature, wherein
The second signal feature is associated with the setting parameter.
In one possible implementation, described device further includes power supply module, is used for as the ultrasonic module, institute
It states signal acquisition component and the control assembly provides electric power.
In one possible implementation, described device further includes display component, for showing and the physiologic information
At least one of the corresponding physiologic information of signal and first signal characteristic.
In one possible implementation, the physiologic information signal includes heart rate signal, blood pressure signal, respiratory rate
At least one of signal and temperature signals.
In one possible implementation, the signal characteristic of the ultrasonic signal includes frequency, amplitude, pulsewidth, prolongs
At least one of slow and phase.
Flexible ultrasonic wave generating device according to an embodiment of the present disclosure, by flexible substrates come bearing ultrasonic component,
Signal acquisition component and control assembly can be attached at human body surface, realize the noninvasive stimulation to carotid sinus, and believe according to physiology
The signal characteristic of ultrasonic wave is adjusted in information signal, accurately stimulates carotid sinus, to realize to the accurate of physiological status
It adjusts.
According to below with reference to the accompanying drawings to detailed description of illustrative embodiments, the other feature and aspect of the disclosure will become
It is clear.
Detailed description of the invention
Comprising in the description and constituting the attached drawing of part of specification and specification together illustrates the disclosure
Exemplary embodiment, feature and aspect, and for explaining the principles of this disclosure.
Fig. 1 is the schematic diagram of flexible ultrasonic wave generating device shown according to an exemplary embodiment;
Fig. 2 is the flow chart shown according to an exemplary embodiment for emitting ultrasonic signal according to physiologic information signal;
Fig. 3 is the flow chart shown according to an exemplary embodiment for emitting ultrasonic signal according to setting parameter;
Fig. 4 is the flow chart shown according to an exemplary embodiment for making ultrasonic signal focus on target area;
Fig. 5 is the schematic diagram of flexible ultrasonic wave generating device shown according to an exemplary embodiment.
Specific embodiment
Various exemplary embodiments, feature and the aspect of the disclosure are described in detail below with reference to attached drawing.It is identical in attached drawing
Appended drawing reference indicate element functionally identical or similar.Although the various aspects of embodiment are shown in the attached drawings, remove
It non-specifically points out, it is not necessary to attached drawing drawn to scale.
Dedicated word " exemplary " means " being used as example, embodiment or illustrative " herein.Here as " exemplary "
Illustrated any embodiment should not necessarily be construed as preferred or advantageous over other embodiments.
In addition, giving numerous details in specific embodiment below to better illustrate the disclosure.
It will be appreciated by those skilled in the art that without certain details, the disclosure equally be can be implemented.In some instances, for
Method, means, element and circuit well known to those skilled in the art are not described in detail, in order to highlight the purport of the disclosure.
Fig. 1 is the schematic diagram of flexible ultrasonic wave generating device shown according to an exemplary embodiment.As shown in Figure 1, institute
Stating flexible ultrasonic wave sounding device includes:Ultrasonic module 11, signal acquisition component 12, control assembly 13 and flexible substrates 14.
Ultrasonic module 11 is for emitting ultrasonic signal;
Signal acquisition component 12 is used to obtain the physiologic information signal of monitoring object;
Control assembly 13 is used to generate first control signal according to the physiologic information signal, and the first control signal is used
In controlling the ultrasonic module, so that the ultrasonic module emits ultrasonic signal;
Flexible substrates 14 are used for bearing ultrasonic component 11, signal acquisition component 12 and control assembly 13.
Flexible ultrasonic wave generating device according to an embodiment of the present disclosure, by flexible substrates come bearing ultrasonic component,
Signal acquisition component and control assembly can be attached at human body surface, realize the noninvasive stimulation to carotid sinus, and believe according to physiology
The signal characteristic of ultrasonic wave is adjusted in information signal, accurately stimulates carotid sinus, to realize to the accurate of physiological status
It adjusts.
In one possible implementation, if arterial pressure increases, when ductus arteriosus wall is expanded to a certain degree, sense
Feel that nerve endings is excited and provides nerve impulse.(60~180 millimetres of mercury of arterial pressure) in a certain range, carotid sinus
Afferent impulse frequency is directly proportional to the degrees of expansion of ductus arteriosus wall, i.e., arterial pressure is higher, the degree that ductus arteriosus wall is expanded
Higher, the afferent impulse frequency of carotid sinus is also higher.Pressure of the carotid sinus to the pressure change of pulsation than non-pulsation
Change more sensitive, the pulsation feature of arterial pressure is adaptable in this feature and normal body.In the arch of aorta, chest liter
Similar artery sinus is equally existed in the vascular wall of aorta and arteria carotis communis etc., can be used for experiencing arterial pressure, blood pressure increases
Shi Xingfen reflective can cause bradycardia, peripheral vasodilation, blood pressure decline.Therefore, using carotid sinus to human body
The reflective adjustment mechanism of physiological status carries out outside stimulus to the arteries sinus such as carotid sinus, to adjust the physiological status such as blood pressure.
In one possible implementation, using focusing ultrasonic wave to carotid sinus region, is produced from carotid sinus region
The raw stimulation such as acoustic radiation pressure and temperature, carotid sinus discharge nerve impulse after experiencing stimulation, through glossopharyngeal nerve, reach oblongata
Nucleus tractus solitaril, and then body parasympathetic is activated, inhibit stomodaeal nervous system, reduces point of feritin and antidiuretic hormone
Secrete, can be reflexive cause bradycardia, blood volume and blood pressure are reduced, to play the mesh of the treatment diseases such as hypertension and heart failure
's.
In one possible implementation, control assembly 13 can be by one or more application specific integrated circuit
(ASIC), digital signal processor (DSP), digital signal processing appts (DSPD), programmable logic device (PLD), scene can
Gate array (FPGA), controller, microcontroller, microprocessor or other electronic components are programmed to realize, for executing the above method,
The disclosure to the type of control assembly 13 with no restrictions.
In one possible implementation, ultrasonic module 11 can have specific ultrasonic wave according to control signal transmitting
The ultrasonic signal of signal characteristic receives ultrasonic wave, and in this example, ultrasonic module 11 can be ultrasonic transducer, described
Ultrasonic transducer can be made out of a piezoelectric material, and can be converted the electrical signal to mechanical oscillation and be generated ultrasonic wave, can also will be received
The ultrasonic wave arrived carries out acoustic-electric conversion, generates electric signal.The disclosure to the type of ultrasonic module 11 with no restriction.In example
In, the signal characteristic of ultrasonic signal includes at least one of frequency, amplitude, pulsewidth, delay and phase.
In one possible implementation, signal acquisition component 12 can receive wire signal or wireless signal.In example
In, signal acquisition component 12 can be obtained from electrocardiograph monitoring device, blood pressure monitoring device, heart sound monitoring device, monitoring of respiration dress
Set the physiologic information signal at least one of apparatus for testing body temperature.The physiologic information signal includes heart rate signal, blood pressure
At least one of signal, respiratory rate signal and temperature signals.
In one possible implementation, flexible substrates 14 are used for bearing ultrasonic component 11, signal acquisition component 12
With control assembly 13.In this example, flexible substrates 14 are fabricated from a flexible material, and the flexible material is soft, light weight, thick
Spend small, bio-compatibility is good.The flexible material includes silica gel hexamethyldisilazane (PDMS), polyimides (PI) or poly- pair
Phthalic acids plastics (PET) etc., the disclosure to flexible material with no restrictions.Flexible substrates 14 may also include viscous layer, can use
In the neck of fitting measurand, hydrogel, medical dressing or silicon rubber etc. can be used to be made for viscous layer.
In one possible implementation, flexible ultrasonic wave sounding device may also include power supply module, for being described
Ultrasonic module, the signal acquisition component and the control assembly provide electric power.The power supply module can be chargeable electricity
Pond, the disclosure to the type of power supply module with no restrictions.
In one possible implementation, flexible ultrasonic wave sounding device may also include display component, for show with
At least one of the corresponding physiologic information of physiologic information signal and first signal characteristic.In this example, flexible super
Sound wave sounding device can also be connect with terminal device (such as mobile phone etc.), by the physiologic information and the first signal characteristic extremely
It is a kind of less to be shown on the display of terminal device.
In one possible implementation, control assembly 13 can generate first control signal according to physiologic information signal.
Fig. 2 is the flow chart shown according to an exemplary embodiment for emitting ultrasonic signal according to physiologic information signal.
As shown in Fig. 2, emitting ultrasonic signal according to physiologic information signal may include following steps:
In the step s 21, according to the physiologic information signal, the physiological parameter of the monitoring object is determined;
In step S22, according to the physiological parameter of the monitoring object, corresponding with the physiological parameter first is determined
Signal characteristic;
In step S23, according to first signal characteristic, the first control signal is generated, so that the ultrasonic wave
Component transmitting has the ultrasonic signal of first signal characteristic.
In one possible implementation, in the step s 21, control assembly 13 can be obtained by signal acquisition component 12
It fetches from electrocardiograph monitoring device, blood pressure monitoring device, heart sound monitoring device, respiration monitoring device and apparatus for testing body temperature extremely
A kind of few physiologic information signal.The physiologic information signal includes heart rate signal, blood pressure signal, respiratory rate signal and body temperature
At least one of signal.Control assembly 13 can determine the physiological parameter of test object by physiologic information signal, for example, tested
At least one of heart rate, blood pressure, respiratory rate and body temperature of object.
In one possible implementation, in step S22, control assembly 13 can determine tested pair according to physiological parameter
The physical condition of elephant, and according to physical condition come the first signal characteristic corresponding with the physiological parameter.
In one possible implementation, in step S23, control assembly can generate the according to the first signal characteristic
One control signal, first control signal can make ultrasonic signal of the transmitting of ultrasonic module 11 with the first signal characteristic.For example,
First signal characteristic may include the amplitude, pulsewidth and frequency of ultrasonic signal, first control signal can to ultrasonic module 11 into
Row control makes the transmitting of ultrasonic module 11 have the ultrasonic signal of the first signal characteristic.
In this example, the physiological parameter includes blood pressure, if the blood that control assembly 13 is transmitted according to blood pressure monitoring device
Pressure signal can determine whether out that the blood pressure of measurand is higher, then control assembly 13 can be determined to make according to measurand blood pressure by
Survey the first signal characteristic of the ultrasonic signal that object blood pressure reduces, and the blood pressure level of real-time monitoring measurand, while root
Corresponding first signal characteristic is determined according to the real-time blood pressure level of measurand, and generates corresponding first control letter in real time
Number, make ultrasonic module transmitting that there is the ultrasonic wave of corresponding first signal characteristic.Ultrasonic signal is in carotid sinus location
Domain generates acoustic radiation pressure and temperature, and the carotid sinus of measurand is stimulated by ultrasonic signal, makes carotid sinus according to it
The nerve impulse that the stimulation release for the ultrasonic wave experienced can reduce blood pressure, such as distend the blood vessels, the nerve punching that heartbeat slows down
It moves, which reaches tractus solitarius medullae oblongatae core through glossopharyngeal nerve, and then activates body parasympathetic, inhibits sympathetic
Nervous system reduces the secretion of feritin and antidiuretic hormone, reflexive adjusting is carried out to the physiological status of measurand, so that blood
Enlargement of pipe and heartbeat slow down, so that the blood pressure of measurand be made to be reduced to normal level.Control assembly 13 can be according to normal blood
Voltage levels determine the first signal characteristic for keeping the blood pressure level, and generate first control signal, emit ultrasonic module 11
Ultrasonic signal makes measurand keep normal blood pressure level.
Flexible ultrasonic wave generating device according to an embodiment of the present disclosure, can according to the practical physiological status of measurand come
The signal characteristic of accurate judgement ultrasonic signal makes arteria carotis so that emitting ultrasonic signal appropriate carrys out stimulation of carotid sinus
Sinus can accurately be adjusted physiological status, avoided adjusting and excessively caused body injury, also avoid adjusting low efficiency
Under, the unconspicuous situation of effect.
In one possible implementation, control assembly 13 can also according to set the parameters to control ultrasonic module 11,
Make ultrasonic module 11 according to set the parameters to transmitting ultrasonic signal.
Fig. 3 is the flow chart shown according to an exemplary embodiment for emitting ultrasonic signal according to setting parameter.It is described
Flexible ultrasonic wave generating device further includes parameter setting component, and the setting component is for receiving setting parameter, and generation and institute
State the corresponding setting signal of setting parameter.In this example, the setting component may include that remote controler etc. can be to ultrasonic parameters
The component being configured.The disclosure to setting component type with no restriction.
In one possible implementation, as shown in figure 3, control assembly 13 is also used to:
In step S31, third is generated according to the setting signal and controls signal, the third control signal is for controlling
The ultrasonic module, so that ultrasonic module transmitting has the ultrasonic signal of second signal feature, wherein described the
Binary signal feature is associated with the setting parameter.
In one possible implementation, in step S31, control assembly 13 can be connect by signal acquisition component 12
Parameter setting component setting signal is received, and third corresponding with setting signal is generated according to setting signal and controls signal, with control
The transmitting of ultrasonic module 11 has the ultrasonic signal of second signal feature.
In this example, flexible ultrasonic wave generating device can be preset by parameter setting component, such as can set
Set the signal characteristic of ultrasonic wave.The parameter setting component, which can receive, joins the setting that the signal characteristic of ultrasonic wave is configured
Number, such as the frequency and amplitude etc. of settable ultrasonic signal, after setting component receives the setting parameter, produce and
The corresponding setting signal of parameter is set, and the setting signal is sent to signal acquisition component 12.The setting parameter can
Set, can also be set according to the instruction of doctor according to the preference of measurand, the disclosure to setting parameter with no restrictions.
In this example, control assembly 13 receives setting signal by signal acquisition component 12, and by the frequency and width of setting
The signal characteristics such as value generate third control signal as the second signal feature, have the transmitting of ultrasonic module 11
The ultrasonic signal of second signal feature.Ultrasonic module 11 can emit the ultrasonic signal with second signal feature.It is sending out
During penetrating, can real-time monitoring measurand physiological parameter, and make to be tested come real-time adjustment signal feature according to physiological parameter
The physiological parameter of object keeps normal level.
In one possible implementation, flexible ultrasonic wave generating device can also pass through the control to ultrasonic module 11
System, the ultrasonic signal for emitting ultrasonic module 11 focus on target area, and the target area includes carotid sinus place
Region may also comprise the artery sinus region in the arch of aorta, chest aorta ascendens and arteria carotis communis, may also include other by
The tissue that body physiological state is adjusted after to stimulation, the disclosure to target area with no restrictions.
Fig. 4 is the flow chart shown according to an exemplary embodiment for making ultrasonic signal focus on target area.Ultrasound
Wave component 11 is also used to receive the second ultrasonic signal of the monitoring object reflection, and carries out to second ultrasonic signal
Acoustic-electric conversion, determines positioning signal.
In one possible implementation, as shown in figure 4, control assembly 13 is also used to:
In step S41, second control signal is generated according to the positioning signal, the second control signal is for controlling
The ultrasonic module, so that the ultrasonic module transmitting focusing is in the ultrasonic signal of target area, wherein the target
Region is associated with the position location of the positioning signal.
In one possible implementation, ultrasonic module 11 can emit ultrasonic signal, which can quilt
Emit to the body different zones of measurand, the body different zones of measurand can be reflected to ultrasonic module 11 the second to be surpassed
Acoustic signals.Ultrasonic module 11 can carry out acoustic-electric conversion to the second ultrasonic signal, determine positioning signal.
In one possible implementation, in step S41, control assembly 13 can obtain target area according to positioning signal
Domain, and second control signal is generated, target area, realization pair are focused on to control the ultrasonic signal of the transmitting of ultrasonic module 11
Target area accurately stimulates, and in this example, the target area includes carotid sinus region or the arch of aorta, chest
Artery sinus region in aorta ascendens and arteria carotis communis.
In this example, flexible ultrasonic wave generating device can control the super of the transmitting of ultrasonic module 11 by phased array method
Acoustic signals focus on target area, such as so that ultrasonic signal is focused on mesh by One-dimension Phased Array or two dimensional phased battle array method
Mark region.The signal characteristics such as the phase of ultrasonic signal of the transmitting of ultrasonic module 11 are controlled by second control signal, from
And the phase for the ultrasonic signal that multiple ultrasonic modules 11 emit is controlled, the ultrasonic wave letter for emitting multiple ultrasonic modules 11
It number interferes with each other, so that the ultrasonic signal for emitting multiple ultrasonic modules 11 focuses on target area.
In this example, control assembly 13 can generate first control signal and second control signal simultaneously, that is, can simultaneously basis
Physiologic information signal and positioning signal are come signal characteristics such as the amplitude, pulsewidth, frequency and the phases that determine ultrasonic signal.First control
Signal processed and second control signal can synthesize a control signal, have and the first control to control the transmitting of ultrasonic module 11
The ultrasonic signal of the corresponding amplitude of signal, pulsewidth and frequency and phase corresponding with second control signal.
Flexible ultrasonic wave generating device according to an embodiment of the present disclosure, positions target by the ultrasonic signal of reflection
Region makes the ultrasonic signal of transmitting focus on target area, avoids stimulation and damage to nontarget area, realize to mesh
Mark the accurate stimulation in region.
Fig. 5 is the schematic diagram of flexible ultrasonic wave generating device shown according to an exemplary embodiment.As shown in figure 5, soft
Property ultrasonic generator ultrasonic module, signal acquisition component and control assembly be integrated in flexible substrates 14, it is flexible
Substrate 14 can be close to the neck of measurand, reduce the acoustic impedance that ultrasonic wave is propagated in vitro, reduce the decaying of ultrasonic wave.
Control assembly can control ultrasonic module, and the ultrasonic signal for emitting ultrasonic module focuses on target area,
As shown in figure 5, target area is the region where the carotid sinus of external carotid artery, internal carotid and arteria carotis communis intersection.Letter
Number securing component can the physiologic information signal that sends of other physiologic information monitoring devices of real-time reception, control assembly is according to being tested pair
The physiologic information signal of elephant to adjust the signal characteristic of ultrasonic signal in real time, for example, if the blood pressure of measurand is higher,
Flexible ultrasonic wave generating device can determine the signals such as the amplitude, pulsewidth and frequency of ultrasonic signal according to the blood pressure of measurand
Feature.The ultrasonic signal for having the signal characteristic can stimulate carotid sinus, and carotid sinus is made to be had the letter
After the ultrasonic signal stimulation of number feature, nerve impulse is discharged, so that blood vessel dilatation and heartbeat slow down, to pass through carotid sinus
Reflective adjusting the blood pressure of measurand is reduced to normal level.Since the signal characteristic of ultrasonic signal is according to tested
The blood pressure of object and determine in real time, to realize that accurate stimulation to carotid sinus can after carotid sinus is by the stimulation
Blood pressure is accurately adjusted.Control assembly also can receive the setting signal of parameter value setting component, to control ultrasonic wave group
Part is according to the signal characteristic for setting the parameters to adjust ultrasonic signal corresponding with setting signal.
Flexible ultrasonic wave generating device according to an embodiment of the present disclosure, by flexible substrates come bearing ultrasonic component,
Signal acquisition component and control assembly can be attached at human body surface, and smaller, nothing of the realization to carotid sinus is influenced on measurand
Wound stimulation reduces the decaying that ultrasonic wave is propagated in vitro.Pass through the target area where making ultrasonic signal focus on carotid sinus
The accurate stimulation to carotid sinus is realized in domain.It can also be according to the signal characteristic for setting the parameters to adjust ultrasonic signal, Huo Zhegen
It is adjusted according to signal characteristic of the physiologic information signal to ultrasonic wave, to realize the accurate tune to measurand physiological status
Section.
The presently disclosed embodiments is described above, above description is exemplary, and non-exclusive, and
It is not limited to disclosed each embodiment.Without departing from the scope and spirit of illustrated each embodiment, for this skill
Many modifications and changes are obvious for the those of ordinary skill in art field.The selection of term used herein, purport
In the principle, practical application or technological improvement to the technology in market for best explaining each embodiment, or lead this technology
Other general master stations in domain, which lead to technical staff, can understand each embodiment disclosed herein.
Claims (9)
1. a kind of flexible ultrasonic wave generating device, which is characterized in that including:Ultrasonic module, signal acquisition component, control assembly
And flexible substrates,
The ultrasonic module is for emitting ultrasonic signal;
The signal acquisition component is used to obtain the physiologic information signal of monitoring object;
The control assembly is used to generate first control signal according to the physiologic information signal, and the first control signal is used for
The ultrasonic module is controlled, so that the ultrasonic module emits ultrasonic signal;
The flexible substrates are for carrying the ultrasonic module, the signal acquisition component and the control assembly.
2. the apparatus according to claim 1, which is characterized in that the control assembly is generated according to the physiologic information signal
First control signal, including:
According to the physiologic information signal, the physiological parameter of the monitoring object is determined;
According to the physiological parameter of the monitoring object, the first signal characteristic corresponding with the physiological parameter is determined;
According to first signal characteristic, the first control signal is generated, so that ultrasonic module transmitting is with described
The ultrasonic signal of first signal characteristic.
3. the apparatus according to claim 1, which is characterized in that the ultrasonic module is also used to receive the monitoring object
Second ultrasonic signal of reflection, and acoustic-electric conversion is carried out to second ultrasonic signal, determine positioning signal,
The control assembly is also used to generate second control signal according to the positioning signal, and the second control signal is for controlling
The ultrasonic module is made, so that the ultrasonic module transmitting focusing is in the ultrasonic signal of target area, wherein the mesh
It is associated with the position location of the positioning signal to mark region.
4. the apparatus according to claim 1, which is characterized in that described device further includes parameter setting component, the setting
Component generates setting signal corresponding with the setting parameter for receiving setting parameter,
The control assembly is also used to generate third control signal according to the setting signal, and the third control signal is for controlling
The ultrasonic module is made, so that ultrasonic module transmitting has the ultrasonic signal of second signal feature, wherein described
Second signal feature is associated with the setting parameter.
5. the apparatus according to claim 1, which is characterized in that described device further includes power supply module, for being described super
Acoustic wave component, the signal acquisition component and the control assembly provide electric power.
6. the apparatus according to claim 1, which is characterized in that described device further includes display component, for display and institute
State at least one of the corresponding physiologic information of physiologic information signal and first signal characteristic.
7. device described in any one of -6 according to claim 1, which is characterized in that the physiologic information signal includes heart rate
At least one of signal, blood pressure signal, respiratory rate signal and temperature signals.
8. device described in any one of -6 according to claim 1, which is characterized in that the signal characteristic of the ultrasonic signal
Including at least one of frequency, amplitude, pulsewidth, delay and phase.
9. device according to claim 3, which is characterized in that the target area includes carotid sinus region.
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