CN108837098A - 胃克星胶囊中药制剂 - Google Patents

胃克星胶囊中药制剂 Download PDF

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CN108837098A
CN108837098A CN201811033186.5A CN201811033186A CN108837098A CN 108837098 A CN108837098 A CN 108837098A CN 201811033186 A CN201811033186 A CN 201811033186A CN 108837098 A CN108837098 A CN 108837098A
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李新江
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Abstract

本发明公开了一种胃克星胶囊中药制剂，包括以下重量份的原料：木瓜15‑20克，川芎15‑25克，熟地15‑20克，元胡15‑20克，白芍12‑15克，杜仲10‑15克，灵芝10‑15克，牛夕10‑15克，枸杞12‑15克，红参9‑15克，玉竹10‑20克，沙参12‑20克，三七9‑12克，白及10‑15克，地榆10‑14克，茜草9‑15克，降香10‑20克，枳壳12‑18克，青皮12‑17克，橘红9‑13克，鸡内金12‑16克，炒山楂15‑20克，炒麦芽15‑30克，炒神曲15‑25克。本发明能够对胃病进行很好的治疗，一次治愈永不复发，无副作用，制备方法简便，质量标准严格，符合中国药典2015年版的制备标准。

Description

胃克星胶囊中药制剂
技术领域
本发明涉及胃克星胶囊领域，尤其涉及一种胃克星胶囊中药制剂。
背景技术
胃病，是许多与胃相关疾病的统称，它们有相似的症状，如上腹胃脘部不适、疼痛、饭后饱胀、嗳气、返酸，甚至恶心、呕吐等等，临床上常见的胃病有急性胃炎、慢性胃炎、胃溃疡、十二指肠溃疡、胃十二指肠复合溃疡、胃息肉、胃结石、胃的良恶性肿瘤，还有胃黏膜脱垂症、急性胃扩张、幽门梗阻等，最常见的有上腹部不适或疼痛、恶心、呕吐、食欲不振、胃胀、胃痛、嗳气、反酸、不思食欲、消瘦面黄并有常年腹泻，胃炎及十二指肠溃疡的症状则为上腹部烧灼痛，特别是在两顿饭之间，早餐前或在饮用橙汁、咖啡之后发生，严重者可有柏油便、黑便或血便，现有技术中对胃病的治疗大多以药物为主，但是药物的副作用较大，且治疗不彻底，导致胃病反复发生，给患者带来了巨大的困扰。
发明内容
基于背景技术存在的技术问题，本发明提出了胃克星胶囊中药制剂。
本发明提出的胃克星胶囊中药制剂，包括以下重量份的原料：木瓜15-20克，川芎15-25克，熟地15-20克，元胡15-20克，白芍12-15克，杜仲10-15克，灵芝10-15克，牛夕10-15克，枸杞12-15克，红参9-15克，玉竹10-20克，沙参12-20克，三七9-12克，白及10-15克，地榆10-14克，茜草9-15克，降香10-20克，枳壳12-18克，青皮12-17克，橘红9-13克，鸡内金12-16克，炒山楂15-20克，炒麦芽15-30克，炒神曲15-25克，广藿香12-18克，甜地丁12-16克；
其制备方法包括以下步骤：
S1：按照配比称量木瓜、川芎、熟地、元胡、白芍、杜仲、灵芝、牛夕、枸杞、红参、玉竹、沙参、三七，称量完成后进行粉碎打磨，并加水进行混合，制得第一混合药液，然后对白及、地榆、茜草、降香、枳壳、青皮、橘红、鸡内金、炒山楂、炒麦芽、炒神曲、广藿香、甜地丁进行称量，称量完成后进行粉碎打磨，并加水进行混合，制得第二混合药液，对第一混合药液和第二混合药液进行混合，制得第三混合药液；
S2：对S1中所述的第三混合药液煎煮3-5h，煎煮完成后对制得的药液进行过滤，将滤液减压浓缩至相对密度为1.5-1.6的稠膏，然后将稠膏干燥，粉碎，加入淀粉，混合均匀后，制得药物小颗粒，将药物小颗粒装入胶囊，制得胃克星胶囊中药制剂。
优选的，包括以下重量份的原料：木瓜16-19克，川芎16-24克，熟地16-19克，元胡16-19克，白芍13-14克，杜仲11-14克，灵芝11-14克，牛夕11-14克，枸杞13-14克，红参10-14克，玉竹11-19克，沙参13-19克，三七10-11克，白及11-14克，地榆11-13克，茜草10-14克，降香11-19克，枳壳13-17克，青皮13-16克，橘红10-12克，鸡内金13-15克，炒山楂16-19克，炒麦芽16-29克，炒神曲16-24克，广藿香13-17克，甜地丁13-15克。
优选的，所述木瓜，川芎，熟地，元胡，白芍，杜仲，灵芝，牛夕，枸杞，红参，玉竹，沙参，三七的重量比为16-19：16-24：16-19：16-19：13-14：11-14：11-14：11-14：13-14：10-14：11-19：13-19：10-11。
优选的，所述白及，地榆，茜草，降香，枳壳，青皮，橘红，鸡内金，炒山楂，炒麦芽，炒神曲，广藿香，甜地丁的重量比为11-14：11-13：10-14：11-19：13-17：13-16：10-12：13-15：16-19：16-29：16-24：13-17：13-15。
优选的，所述S1中，对木瓜、川芎、熟地、元胡、白芍、杜仲、灵芝、牛夕、枸杞、红参、玉竹、沙参、三七进行粉碎打磨，将粉料放进搅拌机内，搅拌机的搅拌杆转速为2000r/min，搅拌时间为20-30min。
优选的，所述S1中，对白及、地榆、茜草、降香、枳壳、青皮、橘红、鸡内金、炒山楂、炒麦芽、炒神曲、广藿香、甜地丁进行粉碎打磨，将粉料放进搅拌机内，搅拌机的搅拌杆转速为2500r/min，搅拌时间为25-30min。
优选的，所述S2中，对S1中所述的第三混合药液煎煮3.5-4.5h，煎煮完成后对制得的药液进行过滤，将滤液减压浓缩至相对密度为1.55-1.59的稠膏，然后将稠膏干燥，粉碎，加入淀粉，混合均匀后，制得药物小颗粒，将药物小颗粒装入胶囊，制得胃克星胶囊中药制剂。
优选的，所述S1中，将第一混合药液和第二混合药液放进搅拌机内，搅拌机的搅拌杆转速为2300r/min，搅拌时间为15min。
本发明的有益效果是：通过以木瓜为原料能够补偿胰和肠道的分泌，补充胃液的不足，有助于分解蛋白质和淀粉，通过以川芎为原料能够活血行气、祛风止痛，通过以熟地为原料能够补血滋阴，通过以元胡为原料能够活血化瘀、行气止痛，通过以白芍为原料能够平肝止痛、养血调经、敛阴止汗，通过以杜仲为原料能够补益肝肾、强筋壮骨，通过以灵芝为原料能够补气安神、止咳平喘、延年益寿，通过以牛夕为原料能活血通经、补肝肾、强筋骨、利水通淋、引火（血）下行，通过以枸杞为原料能够养肝、滋肾、润肺、补虚益精、清热明目，通过以红参为原料能够大补元气、复脉固脱、益气摄血，通过以玉竹为原料能够养阴、润燥、清热、生津、止咳，通过以沙参为原料能够滋补、祛寒热、清肺止咳，也能治疗心脾痛、头痛，通过以三七为原料能够散瘀止血、消肿定痛，通过以白及为原料能够收敛止血、消肿生肌，通过以地榆为原料能够凉血止血、清热解毒、培清养阴、消肿敛疮，通过以降香为原料能够活血散瘀、止血定痛、降气、辟秽，通过以枳壳为原料能够理气宽中、行滞消胀，通过以青皮为原料能够疏肝破气、消积化滞，通过以橘红为原料能够理气宽中、燥湿化痰，通过以鸡内金为原料能够健胃消食、涩精止遗、通淋化石，通过以炒山楂为原料能够健脾开胃、消食化滞、活血化痰，通过以炒麦芽为原料能够行气消食、健脾开胃、退乳消胀，通过以广藿香为原料能够芳香化浊、和中止呕、发表解暑，通过以甜地丁为原料能够清热解毒、凉血消肿，本发明能够对胃病进行很好的治疗，一次治愈永不复发，无副作用，制备方法简便，质量标准严格，符合中国药典2015年版的制备标准。
具体实施方式
下面结合具体实施例对本发明作进一步解说。
实施例一
本发明提出了胃克星胶囊中药制剂，包括以下重量份的原料：木瓜15克，川芎15克，熟地15克，元胡15克，白芍12克，杜仲10克，灵芝10克，牛夕10克，枸杞12克，红参9克，玉竹10克，沙参12克，三七9克，白及10克，地榆10克，茜草9克，降香10克，枳壳12克，青皮12克，橘红9克，鸡内金12克，炒山楂15克，炒麦芽15克，炒神曲15克，广藿香12克，甜地丁12克；
其制备方法包括以下步骤：
S1：按照配比称量木瓜、川芎、熟地、元胡、白芍、杜仲、灵芝、牛夕、枸杞、红参、玉竹、沙参、三七，称量完成后进行粉碎打磨，并加水进行混合，制得第一混合药液，然后对白及、地榆、茜草、降香、枳壳、青皮、橘红、鸡内金、炒山楂、炒麦芽、炒神曲、广藿香、甜地丁进行称量，称量完成后进行粉碎打磨，并加水进行混合，制得第二混合药液，对第一混合药液和第二混合药液进行混合，制得第三混合药液；
S2：对S1中所述的第三混合药液煎煮3h，煎煮完成后对制得的药液进行过滤，将滤液减压浓缩至相对密度为1.5的稠膏，然后将稠膏干燥，粉碎，加入淀粉，混合均匀后，制得药物小颗粒，将药物小颗粒装入胶囊，制得胃克星胶囊中药制剂。
实施例二
本发明提出了胃克星胶囊中药制剂，包括以下重量份的原料：木瓜17克，川芎20克，熟地17克，元胡18克，白芍13克，杜仲12克，灵芝12克，牛夕13克，枸杞14克，红参12克，玉竹15克，沙参15克，三七10克，白及12克，地榆12克，茜草12克，降香15克，枳壳16克，青皮14克，橘红11克，鸡内金14克，炒山楂17克，炒麦芽20克，炒神曲20克，广藿香15克，甜地丁14克；
其制备方法包括以下步骤：
S1：按照配比称量木瓜、川芎、熟地、元胡、白芍、杜仲、灵芝、牛夕、枸杞、红参、玉竹、沙参、三七，称量完成后进行粉碎打磨，并加水进行混合，制得第一混合药液，然后对白及、地榆、茜草、降香、枳壳、青皮、橘红、鸡内金、炒山楂、炒麦芽、炒神曲、广藿香、甜地丁进行称量，称量完成后进行粉碎打磨，并加水进行混合，制得第二混合药液，对第一混合药液和第二混合药液进行混合，制得第三混合药液；
S2：对S1中所述的第三混合药液煎煮4h，煎煮完成后对制得的药液进行过滤，将滤液减压浓缩至相对密度为1.55的稠膏，然后将稠膏干燥，粉碎，加入淀粉，混合均匀后，制得药物小颗粒，将药物小颗粒装入胶囊，制得胃克星胶囊中药制剂。
实施例三
本发明提出了胃克星胶囊中药制剂，包括以下重量份的原料：木瓜20克，川芎25克，熟地20克，元胡20克，白芍15克，杜仲15克，灵芝15克，牛夕15克，枸杞15克，红参15克，玉竹20克，沙参20克，三七12克，白及15克，地榆14克，茜草15克，降香20克，枳壳18克，青皮17克，橘红13克，鸡内金16克，炒山楂20克，炒麦芽30克，炒神曲25克，广藿香18克，甜地丁16克；
其制备方法包括以下步骤：
S1：按照配比称量木瓜、川芎、熟地、元胡、白芍、杜仲、灵芝、牛夕、枸杞、红参、玉竹、沙参、三七，称量完成后进行粉碎打磨，并加水进行混合，制得第一混合药液，然后对白及、地榆、茜草、降香、枳壳、青皮、橘红、鸡内金、炒山楂、炒麦芽、炒神曲、广藿香、甜地丁进行称量，称量完成后进行粉碎打磨，并加水进行混合，制得第二混合药液，对第一混合药液和第二混合药液进行混合，制得第三混合药液；
S2：对S1中所述的第三混合药液煎煮5h，煎煮完成后对制得的药液进行过滤，将滤液减压浓缩至相对密度为1.6的稠膏，然后将稠膏干燥，粉碎，加入淀粉，混合均匀后，制得药物小颗粒，将药物小颗粒装入胶囊，制得胃克星胶囊中药制剂。
通过实施例一、二、三制得的胃克星胶囊中药制剂给患者饭前服用，成人早晚两次，每次8粒；7-12岁儿童，3-4粒，治愈98%以上。
以上所述，仅为本发明较佳的具体实施方式，但本发明的保护范围并不局限于此，任何熟悉本技术领域的技术人员在本发明揭露的技术范围内，根据本发明的技术方案及其发明构思加以等同替换或改变，都应涵盖在本发明的保护范围之内。

Claims (8)

1.胃克星胶囊中药制剂，其特征在于，包括以下重量份的原料：木瓜15-20克，川芎15-25克，熟地15-20克，元胡15-20克，白芍12-15克，杜仲10-15克，灵芝10-15克，牛夕10-15克，枸杞12-15克，红参9-15克，玉竹10-20克，沙参12-20克，三七9-12克，白及10-15克，地榆10-14克，茜草9-15克，降香10-20克，枳壳12-18克，青皮12-17克，橘红9-13克，鸡内金12-16克，炒山楂15-20克，炒麦芽15-30克，炒神曲15-25克，广藿香12-18克，甜地丁12-16克；
其制备方法包括以下步骤：
S1：按照配比称量木瓜、川芎、熟地、元胡、白芍、杜仲、灵芝、牛夕、枸杞、红参、玉竹、沙参、三七，称量完成后进行粉碎打磨，并加水进行混合，制得第一混合药液，然后对白及、地榆、茜草、降香、枳壳、青皮、橘红、鸡内金、炒山楂、炒麦芽、炒神曲、广藿香、甜地丁进行称量，称量完成后进行粉碎打磨，并加水进行混合，制得第二混合药液，对第一混合药液和第二混合药液进行混合，制得第三混合药液；
S2：对S1中所述的第三混合药液煎煮3-5h，煎煮完成后对制得的药液进行过滤，将滤液减压浓缩至相对密度为1.5-1.6的稠膏，然后将稠膏干燥，粉碎，加入淀粉，混合均匀后，制得药物小颗粒，将药物小颗粒装入胶囊，制得胃克星胶囊中药制剂。
2.根据权利要求1所述的胃克星胶囊中药制剂，其特征在于，包括以下重量份的原料：木瓜16-19克，川芎16-24克，熟地16-19克，元胡16-19克，白芍13-14克，杜仲11-14克，灵芝11-14克，牛夕11-14克，枸杞13-14克，红参10-14克，玉竹11-19克，沙参13-19克，三七10-11克，白及11-14克，地榆11-13克，茜草10-14克，降香11-19克，枳壳13-17克，青皮13-16克，橘红10-12克，鸡内金13-15克，炒山楂16-19克，炒麦芽16-29克，炒神曲16-24克，广藿香13-17克，甜地丁13-15克。
3.根据权利要求1所述的胃克星胶囊中药制剂，其特征在于，所述木瓜，川芎，熟地，元胡，白芍，杜仲，灵芝，牛夕，枸杞，红参，玉竹，沙参，三七的重量比为16-19：16-24：16-19：16-19：13-14：11-14：11-14：11-14：13-14：10-14：11-19：13-19：10-11。
4.根据权利要求1所述的胃克星胶囊中药制剂，其特征在于，所述白及，地榆，茜草，降香，枳壳，青皮，橘红，鸡内金，炒山楂，炒麦芽，炒神曲，广藿香，甜地丁的重量比为11-14：11-13：10-14：11-19：13-17：13-16：10-12：13-15：16-19：16-29：16-24：13-17：13-15。
5.根据权利要求1所述的胃克星胶囊中药制剂，其特征在于，所述S1中，对木瓜、川芎、熟地、元胡、白芍、杜仲、灵芝、牛夕、枸杞、红参、玉竹、沙参、三七进行粉碎打磨，将粉料放进搅拌机内，搅拌机的搅拌杆转速为2000r/min，搅拌时间为20-30min。
6.根据权利要求1所述的胃克星胶囊中药制剂，其特征在于，所述S1中，对白及、地榆、茜草、降香、枳壳、青皮、橘红、鸡内金、炒山楂、炒麦芽、炒神曲、广藿香、甜地丁进行粉碎打磨，将粉料放进搅拌机内，搅拌机的搅拌杆转速为2500r/min，搅拌时间为25-30min。
7.根据权利要求1所述的胃克星胶囊中药制剂，其特征在于，所述S2中，对S1中所述的第三混合药液煎煮3.5-4.5h，煎煮完成后对制得的药液进行过滤，将滤液减压浓缩至相对密度为1.55-1.59的稠膏，然后将稠膏干燥，粉碎，加入淀粉，混合均匀后，制得药物小颗粒，将药物小颗粒装入胶囊，制得胃克星胶囊中药制剂。
8.根据权利要求1所述的胃克星胶囊中药制剂，其特征在于，所述S1中，将第一混合药液和第二混合药液放进搅拌机内，搅拌机的搅拌杆转速为2300r/min，搅拌时间为15min。
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