CN108806446A - A kind of production method of diagnosis of early gestation teaching mode and application - Google Patents
A kind of production method of diagnosis of early gestation teaching mode and application Download PDFInfo
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- CN108806446A CN108806446A CN201711188749.3A CN201711188749A CN108806446A CN 108806446 A CN108806446 A CN 108806446A CN 201711188749 A CN201711188749 A CN 201711188749A CN 108806446 A CN108806446 A CN 108806446A
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- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
- G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
- G09B23/28—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
- G09B23/281—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine for pregnancy, birth or obstetrics
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- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
- G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
- G09B23/28—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
- G09B23/286—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine for scanning or photography techniques, e.g. X-rays, ultrasonics
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Abstract
The present invention provides a kind of production methods of diagnosis of early gestation teaching mode, include the following steps：Step (1)：According to the corresponding embryo model of body ruler data creating of different gestational age embryo；Step (2)：Corresponding embryo's teaching mode is made based on above-mentioned embryo model；Step (3)：Above-mentioned embryo's teaching mode is placed in the isolating device of the first solution and integrally submerge fill second of solution apparatus for placing in；Step (4)：The daubing coupling agent on the probe of B-ultrasonic instrument for veterinary use, it immerses and observes embryo's teaching mode form in second of solution of apparatus for placing, with cyesiognosis outside this analogue body, diagnosis of early gestation teaching mode through the invention carries out diagnosis of early gestation to cow, the cyesiognosis of cow can be made to do sth. in advance into 30d after breeding, reduce nonpregnant rate, reduce the fodder grass wasting of resources caused by cow is nonpregnant, reproductive efficiency is improved, industrial economy benefit is increased.
Description
Technical field
The present invention relates to teaching fields, and in particular to a kind of diagnosis of early gestation teaching mode production method and answer
With.
Background technology
B ultrasound diagnostic imaging is to launch high-frequency ultrasonic through piezoelectric effect using probe to penetrate body tissue echogenicity,
Echo is received by probe again become high frequency electrical signal after sends host to, detected after enhanced processing in being shown on fluorescent screen
A kind of modern video diagnostic technology of site tissue section ultrasonogram.Early in mid-term the 1970s, when B ultrasound technology is used for horse
Cyesiognosis success after, be just known as the revolutionary variation of Disease Diagnosis of Veterinary technology, radiated after rectal palpation and Blood Hormone
Having grown area research most in everybody dirty swine since immunoassays has far-reaching technical progress.At this stage, ultrasonic diagnostic technique, especially
It is B ultrasound video diagnostic technology, is at home and abroad widely used in the diagnosis of early gestation of animal.
The Technology on Early-Pregnancy Diagnosis of ox has two methods of indirect detection and directly detection at present.The method of indirect detection compared with
It is more, but it is unable to Site Detection mostly, it is desirable that it is carried out in having conditional laboratory, of high cost, cumbersome, result is divided sometimes
Analysis will produce subjective erroneous judgement.Direct method is mainly using examination per rectum and B ultrasound detection method.Examination per rectum is examiner's hand
Across rectum touch gravid uterus, the situation of change of fetus and fetal membrane, and thus judge whether ox is pregnant.This method is at low cost,
Can be made instantly available as a result, but operating technology be not easy to grasp.B ultrasound video diagnostic technology is safe, it is not damaged, easy to operate,
Sensibility and specificity is high, and as a result rapid and image definition is intuitive, can usually observe directly blastular, idiosome, movement of the foetus and placenta
Deng pregnancy feature.
Invention content
In order to solve the defect of abrasive article insufficient supply currently on the market, the present invention provides a kind of early pregnancies to examine
The production method of disconnected teaching mode and application, diagnosis of early gestation teaching mode through the invention carry out early pregnancy to cow
Diagnosis can be such that the cyesiognosis of cow does sth. in advance into 30d after breeding, reduce nonpregnant rate, reduce the forage grass caused by cow is nonpregnant
Expect the wasting of resources, improve reproductive efficiency, increases industrial economy benefit.
The present invention provides a kind of production methods of diagnosis of early gestation teaching mode, include the following steps：
Step (1)：According to the corresponding embryo model of body ruler data creating of different gestational age embryo；
Step (2)：Corresponding embryo's teaching mode is made based on above-mentioned embryo model；
Step (3)：Above-mentioned embryo's teaching mode is placed in the isolating device of the first solution and integrally submerges Sheng
In the apparatus for placing for having second of solution；
Step (4)：The daubing coupling agent on the probe of B-ultrasonic instrument for veterinary use is immersed in second of solution of apparatus for placing and is observed
Embryo's teaching mode form, with cyesiognosis outside this analogue body.
Above-mentioned production method, wherein in the step (1), the embryo is compared to the bulky animal embryo of adult dogs
Tire.
Above-mentioned production method, wherein the step (2) specifically includes：
Step (2.1)：By taro meal and water according to 1:2 ratio dissolving, then 1% polyvinylpyrrolidone (PVP) is added,
Base-material is obtained after mixing；
Step (2.2)：Above-mentioned uniformly mixed base-material is poured into embryo model；
Step (2.3)：The embryo model for filling base-material is put into water and is stopped when being heated to gel state
Heating, then takes out embryo's teaching mode of semi-finished product；
Step (2.4)：The above-mentioned embryo's teaching mode made is put into refrigerator freeze forming to get finished product is arrived
Embryo's teaching mode.
Above-mentioned production method, wherein in the step (3), wherein the first described solution, second of solution can be equal
For water, the isolating device can be valve bag, and the apparatus for placing can be beaker；Specially：The embryo prepared is taught
Model is learned to be placed in water-filled valve bag and integrally submerge in the beaker for filling with water.
Above-mentioned production method, wherein the step (2.3) further includes：
Step (2.3.1)：The beaker for filling water is placed on every asbestos gauge and ceramic tile on electric furnace, the embryo of base-material then will be filled
Loose tool type, which is placed in beaker, makes it float on liquid level, turns on the switch knob and is heated, wherein heating and temperature control is in 80-95
Degree, heating time are 30-45 minutes.
Simultaneously in another embodiment, the present invention also provides a kind of application of diagnosis of early gestation teaching mode, roots
According to the body footage of different gestational age fetus according to made embryo's teaching mode, it can more be clearly observed different gestational age fetus
Form；Probably it can also can speculate fetus is approximately at how many according to the body ruler length of fetus in observed B ultrasound image
Monthly age.
The invention has the advantages that：1, diagnosis of early gestation teaching mode through the invention carries out cow early
Phase cyesiognosis can be such that the cyesiognosis of cow does sth. in advance into 30d after breeding, reduce nonpregnant rate, and reduction causes because cow is nonpregnant
The fodder grass wasting of resources, improve reproductive efficiency, increase industrial economy benefit.
Description of the drawings
Upon reading the detailed description of non-limiting embodiments with reference to the following drawings, the present invention and its feature, outer
Shape and advantage will become more apparent upon.Identical label indicates identical part in whole attached drawings.Not deliberately proportionally
Draw attached drawing, it is preferred that emphasis is the purport of the present invention is shown.
Fig. 1 is that embryo's teaching mode provided by the invention makes schematic diagram.
Specific implementation mode
In the following description, a large amount of concrete details are given in order to provide more thorough understanding of the invention.So
And it is obvious to the skilled person that the present invention may not need one or more of these details and be able to
Implement.In other examples, in order to avoid with the present invention obscure, for some technical characteristics well known in the art not into
Row description.
In order to thoroughly understand the present invention, detailed step and detailed structure will be proposed in following description, so as to
Illustrate technical scheme of the present invention.Presently preferred embodiments of the present invention is described in detail as follows, however other than these detailed descriptions, this
Invention can also have other embodiment.
Shown in referring to Fig.1, the present invention provides a kind of production methods of diagnosis of early gestation teaching mode, including following step
Suddenly：
Step (1)：According to the corresponding embryo model of body ruler data creating of different gestational age embryo, wherein embryo be compared to
The bulky animal embryo of adult dogs, such as：The relatively large animal such as ox, pig, the present invention is by taking ox as an example, according to different gestational age
The body footage evidence of tire ox selects suitable material to make the tire ox model of different gestational age；
Step (2)：Corresponding embryo's teaching mode is made based on above-mentioned embryo model, is specifically included：
Step (2.1)：By taro meal and water according to 1:2 ratio dissolving, then 1% polyvinylpyrrolidone (PVP) is added,
Base-material is obtained after mixing；
Step (2.2)：Above-mentioned uniformly mixed base-material is poured into embryo model；
Step (2.3)：The embryo model for filling base-material is put into water and is stopped when being heated to gel state
Heating, then takes out embryo's teaching mode of semi-finished product；
Step (2.4)：The above-mentioned embryo's teaching mode made is put into refrigerator freeze forming to get finished product is arrived
Embryo's teaching mode；
Step (3)：Above-mentioned embryo's teaching mode is placed in the isolating device of the first solution and integrally submerges Sheng
In the apparatus for placing for having second of solution, that is to say, that the tire ox model prepared is placed in the valve bag for filling water, is simulated
Uterus environment.
Step (4)：The daubing coupling agent on the probe of B-ultrasonic instrument for veterinary use is immersed in second of solution of apparatus for placing and is observed
Embryo's teaching mode form, that is to say, that hold B-ultrasonic instrument for veterinary use observation tire ox form, the early pregnancy of in-vitro simulated big animal is examined
It is disconnected, with cyesiognosis outside this analogue body, it can more be clearly observed the form of different gestational age tire ox；In turn, according to institute
The body ruler length of tire ox, can probably speculate tire ox is approximately at how many monthly age in the B ultrasound image observed.Such two aspect carries out
Teaching, can more fully teach big animal on the basis of toy diagnosis of early gestation more universal at present is imparted knowledge to students
Diagnosis of early gestation knowledge enables the college student of the relevant specialities such as animal medicine comprehensively and expertly grasps associative skills.
In the present invention, the tire ox form of the early pregnancy by simulating big animal, to be used to impart knowledge to students, so as to realize
It can quickly judge, according to the body ruler length of tire ox in observed B ultrasound image, can probably speculate tire ox in practical operation
How many monthly age be approximately at.By taking ox as an example, detected in due course in the first trimester of cow gestation, it may be determined that the early stage of fetus
Developmental state.When general gestational age is 1 month, embryo is C-shaped or L shapes, head and body can be distinguished from B ultrasound within 33 days or so.33
The embryo's head length and body length of~50 days gestational ages are of substantially equal, but body length be slightly larger than it is long.In actual production, usually in gestation
2 months or so afterwards carry out detection and the sex identification of pregnant tire number.So as to apply in the body according to different gestational age fetus
Footage can more be clearly observed the form of different gestational age tire ox according to made embryo's teaching mode；According further to mould
Type probably can also can speculate fetus is approximately at how many monthly age according to the body ruler length of fetus in observed B ultrasound image,
Accuracy rate can reach 99% or more.
In an of the invention preferred but unrestricted embodiment, in step (3), wherein the first solution, second of solution
Can be water, isolating device can be valve bag, or other similar devices, apparatus for placing can be beaker；Tool
Body is：The embryo's teaching mode prepared is placed in water-filled valve bag and is integrally submerged in the beaker for filling with water.
In a preferred but unrestricted embodiment of the invention, step (2.3) further includes：Step (2.3.1)：Water will be filled
Beaker 1 be placed on electric furnace 4 every asbestos gauge 2 and ceramic tile 3, then the embryo model 5 for filling base-material, which is placed in beaker, makes it float
It is heated on liquid level, turning on the switch knob 6, for wherein heating and temperature control in 80-95 degree, heating time is 30-45 minutes.
Embodiment 1
A kind of production method of diagnosis of early gestation teaching mode, includes the following steps：
Step (1)：According to the corresponding tire ox embryo model of body ruler data creating of different gestational age tire ox embryo；Step (2)：
Corresponding tire ox embryo's teaching mode is made based on above-mentioned tire ox embryo model, is specifically included：Step (2.1)：By taro meal
With water according to 1:2 ratio dissolving, then 1% polyvinylpyrrolidone (PVP) is added, base-material is obtained after mixing；Step
(2.2)：Above-mentioned uniformly mixed base-material is poured into tire ox embryo model；Step (2.3)：Tire ox embryo's mould of base-material will be filled
Type is put into water and is heated to stopping heating when gel state, and the tire ox embryo teaching mould of semi-finished product is then taken out
Type, wherein heating temperature are 90 degree, 40 minutes；
Step (2.4)：The above-mentioned tire ox embryo's teaching mode made is put into freeze forming in refrigerator, cryogenic temperature
For minus 20 degrees, the time is 2 hours to get to tire ox embryo's teaching mode of finished product；Step (3)：The embryo that will be prepared
Teaching mode is placed in water-filled valve bag and integrally submerges in the beaker for filling with water.Step (4)：In the spy of B-ultrasonic instrument for veterinary use
Daubing coupling agent on head immerses and observes tire ox embryo's teaching mode form in beaker, can be compared with cyesiognosis outside this analogue body
To be clearly observed the form of different gestational age tire ox.
Comparative example 1
With embodiment 1 difference lies in, the configuration of base-material, base-material is configured in the present embodiment：Taro meal and water are pressed
According to 1:1 ratio dissolving, then 1% polyvinylpyrrolidone (PVP) is added, base-material is obtained after mixing.
Comparative example 2
With embodiment 1 difference lies in, the configuration of base-material, base-material is configured in the present embodiment：Taro meal and water are pressed
According to 2:1 ratio dissolving, then 1% polyvinylpyrrolidone (PVP) is added, base-material is obtained after mixing.
Comparative example 3
With embodiment 1 difference lies in, the configuration of base-material, base-material is configured in the present embodiment：Taro meal and water are pressed
According to 1:2 ratio dissolving, then 1% agar is added, base-material is obtained after mixing.
Comparative example 4
With embodiment 1 difference lies in, the configuration of base-material, base-material is configured in the present embodiment：Taro meal and water are pressed
According to 1:2 ratio dissolving, then 0.5% agar and 0.5% polyvinylpyrrolidone (PVP) are added, base-material is obtained after mixing.
Comparative example 5
The step of difference lies in, steps (2.3), the present embodiment with embodiment 1 (2.3) be：The tire ox of base-material will be filled
Embryo model is put into water and is heated to stopping heating when gel state, and the tire ox embryo religion of semi-finished product is then taken out
Model is learned, wherein heating temperature is 80 degree, 45 minutes.
Comparative example 6
The step of difference lies in, steps (2.3), the present embodiment with embodiment 1 (2.3) be：The tire ox of base-material will be filled
Embryo model is put into water and is heated to stopping heating when gel state, and the tire ox embryo religion of semi-finished product is then taken out
Model is learned, wherein heating temperature is 95 degree, 30 minutes.
Comparative example 7
With embodiment 1 difference lies in step (2.4), (2.4) are by the above-mentioned tire ox made the step of the present embodiment
Embryo's teaching mode is put into freeze forming in refrigerator, and cryogenic temperature is subzero 10 degree, and the time is 3 hours to get to finished product
Tire ox embryo's teaching mode.
1- comparative examples 7 prepare diagnosis of early gestation teaching mode respectively by the following examples, wherein with cow
Embryo for illustrate.Each embodiment prepares 32 days, 45 days, 59 days tire ox models respectively, wherein with actual tire
Prepared by ox embryo data, tire ox model prepared by each embodiment applies the actual conditions in teaching as shown in table 1 below.
Table 1
From above-mentioned table 1, it is seen that, model prepared by embodiment 1 is most suitable for, for imparting knowledge to students, simulating early embryo
Situations such as soft or hard quality of tire, long long and body, can reach 99%, and the tire ox with the goodness of fit of practical tire ox embryo morphology
Embryo's teaching mode has good stability, and it is longer to continue instructional blocks of time.Comparative example 1 and comparative example 2 are because of its tire ox embryo
Taro meal dissolving ratio used in prenatal culture modelling is not suitable for, and influences the quality of tire ox embryo's teaching mode, cannot be preferable
Simulation softness.Comparative example 3 and comparative example 4 base-material in the manufacturing process of tire ox embryo's teaching mode are matched
Fang Butong maintains the function of tire ox embryo's teaching mode stability slightly poor.Comparative example 5 and comparative example 6 are making
The temperature and duration heated when tire ox embryo's teaching mode, which limits it, cannot be fully achieved gel state, and then can not be preferably
The practical tire ox embryo morphology of simulation, and be easy to shrink, stability is very poor.The only freezing conditions of comparative example 7 are slightly different, tire
Ox embryo teaching mode can preferable simulation practical tire ox embryo morphology, but compared with Example 1, stability is still slightly
Shortcoming.Integrated comparative, by prolonged experimental demonstration, embodiment 1 it is various under the conditions of prepared diagnosis of early gestation mould
Type is most suitable for for imparting knowledge to students.
Diagnosis of early gestation teaching mode through the invention carries out diagnosis of early gestation to cow, can make the gestation of cow
Diagnosis in practical applications, can be diagnosed quickly ahead of time to after breeding in 30d, reduce nonpregnant rate, and reduction is led because cow is nonpregnant
The fodder grass wasting of resources of cause improves reproductive efficiency, increases industrial economy benefit.
Presently preferred embodiments of the present invention is described above.It is to be appreciated that the invention is not limited in above-mentioned
Particular implementation, wherein the equipment and structure be not described in detail to the greatest extent are construed as giving reality with the common mode in this field
It applies；Any technical person familiar with the field, without departing from the scope of the technical proposal of the invention, all using the disclosure above
Methods and technical content many possible changes and modifications are made to technical solution of the present invention, or be revised as equivalent variations etc.
Embodiment is imitated, this is not affected the essence of the present invention.Therefore, every content without departing from technical solution of the present invention, foundation
The technical spirit any simple modifications, equivalents, and modifications made to the above embodiment of the present invention, still fall within the present invention
In the range of technical solution protection.
Claims (6)
1. a kind of production method of diagnosis of early gestation teaching mode, which is characterized in that include the following steps：
Step (1)：According to the corresponding embryo model of body ruler data creating of different gestational age embryo；
Step (2)：Corresponding embryo's teaching mode is made based on above-mentioned embryo model；
Step (3)：Above-mentioned embryo's teaching mode is placed in the isolating device of the first solution and is integrally submerged and fills
In the apparatus for placing of two kinds of solution；
Step (4)：The daubing coupling agent on the probe of B-ultrasonic instrument for veterinary use immerses in second of solution of apparatus for placing and observes embryo
Teaching mode form, with cyesiognosis outside this analogue body.
2. a kind of production method of diagnosis of early gestation teaching mode as described in claim 1, which is characterized in that the step
(1) in, the embryo is compared to the bulky animal embryo of adult dogs.
3. a kind of production method of diagnosis of early gestation teaching mode as claimed in claim 2, which is characterized in that the step
(2) it specifically includes：
Step (2.1)：By taro meal and water according to 1:2 ratio dissolving, then 1% polyvinylpyrrolidone (PVP) is added, it mixes
Base-material is obtained after uniformly；
Step (2.2)：Above-mentioned uniformly mixed base-material is poured into embryo model；
Step (2.3)：The embryo model for filling base-material is put into water and is heated to stopping heating when gel state,
Then take out embryo's teaching mode of semi-finished product；
Step (2.4)：The above-mentioned embryo's teaching mode made is put into refrigerator freeze forming to get to the embryo of finished product
Teaching mode.
4. a kind of production method of diagnosis of early gestation teaching mode as claimed in claim 3, which is characterized in that the step
(3) in, wherein the first described solution, second of solution can be water, the isolating device can be valve bag, the Sheng
It can be beaker to put device；Specially：The embryo's teaching mode prepared is placed in water-filled valve bag and is integrally submerged
In the beaker for filling with water.
5. a kind of production method of diagnosis of early gestation teaching mode as claimed in claim 3, which is characterized in that the step
(2.3) further include：
Step (2.3.1)：The beaker for filling water is placed on every asbestos gauge and ceramic tile on electric furnace, embryo's mould of base-material then will be filled
Type, which is placed in beaker, makes it float on liquid level, turns on the switch knob and is heated, and wherein heating and temperature control adds in 80-95 degree
The hot time is 30-45 minutes.
6. a kind of application of diagnosis of early gestation teaching mode, which is characterized in that according to the body footage of different gestational age fetus according to institute
Embryo's teaching mode of making can more be clearly observed the form of different gestational age fetus；It can also be observed by
B ultrasound image in fetus body ruler length, probably can speculate fetus is approximately at how many monthly age.
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| CN103617761A (en) * | 2013-12-09 | 2014-03-05 | 北京化工大学 | High-precision multi-tissue simulation fetal model |
| CN203706551U (en) * | 2014-01-14 | 2014-07-09 | 罗红缨 | Fetus ultrasonic inspection simulation practice model |
| CN204143740U (en) * | 2014-10-17 | 2015-02-04 | 济南市中心医院 | Multiparity's detection model for pregnant woman |
| US20170110032A1 (en) * | 2015-10-16 | 2017-04-20 | Virtamed Ag | Ultrasound simulation system and tool |
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Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101816590A (en) * | 2010-03-10 | 2010-09-01 | 南方医科大学 | Method for manufacturing navigation template of human bone surgery and female die thereof |
| JP2014032253A (en) * | 2012-08-01 | 2014-02-20 | Azabu Jui Gakuen | Development of animal model for education of participated type veterinary medicine/animal husbandry |
| CN103617761A (en) * | 2013-12-09 | 2014-03-05 | 北京化工大学 | High-precision multi-tissue simulation fetal model |
| CN203706551U (en) * | 2014-01-14 | 2014-07-09 | 罗红缨 | Fetus ultrasonic inspection simulation practice model |
| CN204143740U (en) * | 2014-10-17 | 2015-02-04 | 济南市中心医院 | Multiparity's detection model for pregnant woman |
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Application publication date: 20181113 |