CN108802006A - A kind of computational methods of preparation and its surface enhanced factor with SERS substrates - Google Patents
A kind of computational methods of preparation and its surface enhanced factor with SERS substrates Download PDFInfo
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- CN108802006A CN108802006A CN201810577529.8A CN201810577529A CN108802006A CN 108802006 A CN108802006 A CN 108802006A CN 201810577529 A CN201810577529 A CN 201810577529A CN 108802006 A CN108802006 A CN 108802006A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
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- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C14/00—Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material
- C23C14/06—Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material characterised by the coating material
- C23C14/14—Metallic material, boron or silicon
- C23C14/18—Metallic material, boron or silicon on other inorganic substrates
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- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C14/00—Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material
- C23C14/22—Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material characterised by the process of coating
- C23C14/24—Vacuum evaporation
- C23C14/26—Vacuum evaporation by resistance or inductive heating of the source
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
- G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
- G01N2021/653—Coherent methods [CARS]
- G01N2021/655—Stimulated Raman
Abstract
A kind of computational methods of preparation and its surface enhanced factor with SERS substrates, are deposited the silver nano-grain of 300nm in AAO templates using the method for thermal evaporation, utilize the surface topography of scanning electron microscope observation sample；Using the AAO templates that deposited silver as substrate, the Surface Enhanced Raman Scattering Spectrum of rhodamine 6G molecule is studied.The result shows that being deposited on the silver nano-grain in AAO templates with thermal evaporation has good SERS characteristics, by testing the theoretical calculation with the surface enhanced factor, enhancing effect depends primarily on the surface topography of sample.
Description
Technical field
The present invention relates to field of nanometer technology more particularly to a kind of preparations and its surface enhanced factor with SERS substrates
Computational methods.
Background technology
The detection technique of raman scattering spectrum is a kind of need not to analyze the structure of matter that detected sample is marked
Means have the characteristics that non-destructive, without contacting.With the development of laser technology and infant laser signal detection reception technique, as
A kind of means of achievable structure of matter molecular level detection, raman scattering spectrum detection technique are expected in biological detection, disease
The fields such as diagnosis, food safety detection, environmental monitoring, chemical analysis obtain reality and are widely applied.
Surface enhanced Raman scattering (SERS) refers to enhancing local using noble metal nano structure under laser action
Electromagnetic field intensity so that the raman scattering spectrum signal strength of accompanying molecule is put near noble metal nano body structure surface
Greatly, to realize a kind of technology of the detection to trace molecules.
Currently, the SERS substrates based on nanometer rough surface or nanostructure are mostly used, to enhance Raman scattering signal
Intensity.The preparation method for the SERS substrates reported mainly have sol particle method, metal electrode electrochemistry wet etch techniques,
Metal nano bead etching technique, self-catalysis VLS chemical syntheses growing technology, electron beam lithography, focused-ion-beam lithography and
Other physical chemistry etching methods etc., these technologies more or less all exist in process complexity or process controllability etc. asks
Topic, it is difficult to which realization is commercially produced on a large scale.
Invention content
The purpose of the present invention is to solve disadvantage existing in the prior art, and propose a kind of with SERS substrates
The computational methods of preparation and its surface enhanced factor.
To achieve the goals above, present invention employs following technical solutions：
A kind of computational methods of preparation and its surface enhanced factor with SERS substrates, include the following steps,
S1, using DM-450A type resistance-type vacuum thermal evaporation coating machines, in AAO templates at room temperature thermal evaporation deposition silver
Nano particle：AAO templates are placed on the workpiece plate away from evaporation source 28cm, and evaporation source is that the purity being placed in molybdenum boat is 99.99%
Argent grain, evaporation initial vacuum chamber air pressure be 4.0 × 10-3Pa, rotational workpieces disk when experiment starts, makes vapor deposition evenly, increases
When power-up flows to 140A~145A, the shutter covered in advance on evaporation source is opened, material vapor will be deposited in template, be evaporated
Rate is about 0.3nm/s, with quartz crystal oscillator film thickness gauge Thickness Monitoring, is prepared into the sample that film thickness is 300nm；
S2, rhodamine 6G is dissolved in ultra-pure water, required concentration is made；5 a concentration of 0.1M of μ L are drawn with micropipette rifle
Rhodamine 6G aqueous solution be added dropwise after silicon substrate surface, natural evaporation silicon substrate surface formed a diameter be about 4mm's
The sample prepared is cut the parts 0.5cm × 0.5cm bubble 30min in rhodamine 6G solution, after taking-up by round R6G films
It is cleaned up with deionized water, and is dried up at room temperature with nitrogen, be used for Raman spectroscopic detection；
S3, the surface enhanced factor that the Molecular Adsorption signal of absorption on the surface of the substrate is calculated using formula.
Preferably, the nominal diameter of AAO templates is 25mm in the step S1, aperture 200nm, film thickness are 60 μm).
Preferably, the surface topography of sample is seen with JSM-7500LV type field emission scanning electron microscopes in the step S1
It surveys.
Preferably, the resistivity of ultra-pure water is more than 18M Ω .cm in the step S2-1。
Preferably, Renishawinvia micro confocal laser Raman spectrometers, excitation wave are used in the step S2
A length of 785nm, laser output power 1mw, spectral resolution 2cm-1, laser is after 20 times of object lens focus, on sample
Spot diameter is 2 μm, the time 10s of each sample collection spectroscopic data, 950~1850cm of scanning range-1。
Compared with prior art, the beneficial effects of the invention are as follows：
1, the present invention deposits the silver nano-grain of 300nm using the method for thermal evaporation in AAO templates, utilizes scanning electron microscope
The surface topography of observing samples；Using the AAO templates that deposited silver as substrate, the surface-enhanced Raman for studying rhodamine 6G molecule dissipates
Penetrate spectrum.The result shows that being deposited on the silver nano-grain in AAO templates with thermal evaporation has good SERS characteristics, pass through
The theoretical calculation of the surface enhanced factor, enhancing effect depend primarily on the surface topography of sample.
2, can finally draw a conclusion through the invention, using AAO templates as substrate, use the method deposition thickness of thermal evaporation for
The silver nano-grain of 300nm when in this, as SERS substrates, can generate good enhancement effect to the R6G molecules of absorption, pass through
The calculating of experiment and the surface enhanced factor (EF), enhancing effect depend primarily on the surface topography of sample；In our scope of experiments
Interior, when the sample that Argent grain average diameter is 93nm, form plate hole size is 103nm is as SERS substrates, enhancement factor is most
Greatly, enhancing effect is best.
Description of the drawings
Fig. 1 is the surface topography SEM figures of blank AAO templates (a) and sample (d)；
Fig. 2 be the rhodamine 6G Molecular Adsorption of (a) a concentration of 0.1M on a silicon substrate, when a concentration of 10-4M of R6G, is adsorbed on sky
The SERS collection of illustrative plates of white AAO templates (b) and sample (c) surface.
Specific implementation mode
The technical scheme in the embodiments of the invention will be clearly and completely described below, it is clear that described implementation
Example is only a part of the embodiment of the present invention, instead of all the embodiments.
A kind of computational methods of preparation and its surface enhanced factor with SERS substrates, utilize DM-450A type resistance-types
Vacuum thermal evaporation coating machine, in AAO templates, (WhatmanCompany is produced, nominal diameter 25mm, aperture 200nm, 60 μ of film thickness
M) thermal evaporation deposition silver nano-grain at room temperature on.Detailed process is as follows：AAO templates are placed on the workpiece plate away from evaporation source 28cm
On, evaporation source is the Argent grain that the purity being placed in molybdenum boat is 99.99%, and the air pressure of evaporation initial vacuum chamber is 4.0 × 10-3Pa,
Rotational workpieces disk when experiment starts, makes vapor deposition evenly, and when increasing electric current to 140A~145A, opening covers on evaporation source in advance
Shutter, material vapor will be deposited in template, and evaporation rate is about 0.3nm/s, with quartz crystal oscillator film thickness gauge Thickness Monitoring,
It is prepared into the sample that film thickness is 300nm.
The surface topography of sample is seen with JSM-7500LV types (accelerating potential 5KV) field emission scanning electron microscope (SEM)
It surveys.
Rhodamine 6G (Rhodamine6G, AladdinChemistryCo.Ltd) is dissolved in resistivity and is more than 18M Ω .cm-1
Ultra-pure water in, required concentration is made.The rhodamine 6G aqueous solution that 5 a concentration of 0.1M of μ L are drawn with micropipette rifle is added dropwise
Silicon substrate surface forms the round R6G films that a diameter is about 4mm, by what is prepared after natural evaporation in silicon substrate surface
Sample cuts the parts 0.5cm × 0.5cm bubble 30min in rhodamine 6G solution, is cleaned up with deionized water after taking-up, and
It is dried up at room temperature with nitrogen, is used for Raman spectroscopic detection.Experiment uses Renishawinvia micro confocal LR laser raman light
Spectrometer, excitation wavelength 785nm, laser output power 1mw, spectral resolution 2cm-1, laser after 20 times of object lens focus,
Spot diameter on sample is 2 μm, the time 10s of each sample collection spectroscopic data, 950~1850cm of scanning range-1。
Embodiment one
By the way of thermal evaporation, can prepare the surface of different size of silver nano-grain sample will show difference
Pattern.The silver nanoparticle of sample is obtained by the measurement statistics to a large amount of particles and hole (50~100) size according to Fig. 1
Particle mid diameter is that 93nm and AAO form plate hole sizes are 103nm.
Embodiment two
Above-mentioned sample is used to use concentration of aqueous solution for 10 as the substrate material of SERS-4The rhodamine 6G of M is probe point
Son obtains the enhancing Raman scattering signal of rhodamine 6G, and Raman spectrum (such as Fig. 2 of the rhodamine 6G by blank AAO templates
(b) shown in) and the rhodamine 6G of 0.1M is directly added drop-wise to the Raman signal (such as Fig. 2 (a) shown in) in silicon base as a comparison.
It can be clearly seen that from measurement result：When the rhodamine 6G being diluted is adsorbed in blank AAO templates, Raman scattering signal
Intensity is very weak, and when can't see peak value, and being directly added drop-wise in silicon base with the rhodamine 6G of 0.1M, Raman scattering signal is through putting
It can observe its peak value after big twice, after using the sample with silver nano-grain as substrate material, Raman detection is strong
Degree greatly enhances, and obtains the SERS spectra of high s/n ratio.The position of Raman peaks marks wherein 1184cm in the figure in spectral line-1、
1363cm-1、1513cm-1And 1651cm-1It is and the flexible stretching vibration characteristic spectrums of relevant mono- C of C of phenyl ring, 1127cm-1The spectral peak at place
It is to be generated with mono- H bending vibrations of C in the relevant plane of phenyl ring, 1313cm-1It belongs to and the relevant C of phenyl ring
The calculating of the surface enhanced factor (EF)
In order to illustrate the enhancing ability of sample, it is necessary to calculate the surface of the Molecular Adsorption signal of absorption on the surface of the substrate
Enhancement factor (EF).Calculation formula according to pertinent literature enhancement factor is：
(2)：EF=(Isurf/Ibulk/(Nsurf/Nbulk)
Wherein IsurfAnd IbulkSERS integrated intensity and sieve of the rhodamine 6G Molecular Adsorption on sample surfaces are indicated respectively
Red bright 6G Molecular Adsorptions are in the normal Raman spectral signal integrated intensity of silicon substrate surface, NsurfAnd NbulkTwo bases are corresponded to respectively
Bottom surface is by the rhodamine 6G molecule amount of Raman scattering.With 1363cm-1The raman characteristic peak at place is foundation to estimate its enhancing
The factor, peak intensity Isurf/IbulkRatio can be according to fig. 2 data to be calculated be 43.6.
When experiment, 5 μ L (L are added dropwise on a silicon substrate1) a concentration of 0.1M R6G aqueous solutions, after evaporation of the solvent, in substrate table
Face forms diameter (D1) be 4mm or so size R6G films, it is assumed that molecule is equally distributed in 4mm diameter ranges, then
Be adsorbed on silicon substrate surface is by the rhodamine 6G molecule amount of Raman scattering
(3)：Nbulk=0.1 × L1×No×[π×(Do/2)2/π×(D1/2)2
D in formulaoFor 2 μm of laser spot diameter, No=6.02 × 1023.That is Nbulk=7.53 × 1010
It is generally believed that observing a monolayer of the SERS signal essentially from its surface of R6G on Nano silver grain
R6G molecules, it will be assumed that on Nano silver grain surface, saturation has adsorbed the R6G molecules of a monolayer, each R6G molecules institute
Account for the area (A on surfaceo) it is 2.22nm2.Therefore, Nano silver grain surface is adsorbed on by the rhodamine 6G molecule of Raman scattering
Number is
(4)：Nsurf=π × (Do/2)2×R/Ao=R × 1.41 × 106
R is the surface roughness factor in formula, and size can be estimated that the corresponding R of sample is big according to the surface topography of Fig. 1
Small is respectively 1.8.
It is obtained (5) by (3) and (4) formula：Nbulk/Nsurf=5.34 × 104/R
The SERS enhancement factors of sample can be calculated according to formula (2) and (5), result of calculation meter is in table.
Raman enhancement factor (the 1363cm of sample-1)
Show that the SERS enhancement factors of sample are not only related with the design feature of substrate from result of calculation, but also and sample
Surface Nano silver grain size, shape, spacing are related.In our scope of experiments, 300nm silver nanoparticles are deposited in AAO templates
Sample (a diameter of 93nm of Argent grain, form plate hole size are 103nm) corresponding enhancement factor of grain is maximum, there is very strong Raman
Enhancement effect is ideal SERS active substrates material.
It finally draws a conclusion, using AAO templates as substrate, uses the method deposition thickness of thermal evaporation for the silver nanoparticle of 300nm
When in this, as SERS substrates, good enhancement effect can be generated to the R6G molecules of absorption for particle, increased by experiment and surface
The calculating of the strong factor (EF), enhancing effect depend primarily on the surface topography of sample；In our scope of experiments, i.e. AAO templates
For substrate, the silver nano-grain that deposition thickness is 300nm (Argent grain average diameter is 93nm, form plate hole size is 103nm)
When sample is as SERS substrates, enhancement factor is maximum, and enhancing effect is best.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto,
Any one skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its
Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.
Claims (5)
1. a kind of computational methods of preparation and its surface enhanced factor with SERS substrates, which is characterized in that including following step
Suddenly,
S1, using DM-450A type resistance-type vacuum thermal evaporation coating machines, the thermal evaporation deposition silver nanoparticle at room temperature in AAO templates
Particle：AAO templates are placed on the workpiece plate away from evaporation source 28cm, and evaporation source is the silver that the purity being placed in molybdenum boat is 99.99%
The air pressure of particle, evaporation initial vacuum chamber is 4.0 × 10-3Pa, rotational workpieces disk when experiment starts, makes vapor deposition evenly, increases electricity
When flowing to 140A~145A, the shutter covered in advance on evaporation source is opened, material vapor will be deposited in template, evaporation rate
About 0.3nm/s is prepared into the sample that film thickness is 300nm with quartz crystal oscillator film thickness gauge Thickness Monitoring；
S2, rhodamine 6G is dissolved in ultra-pure water, required concentration is made；Sieve of 5 a concentration of 0.1M of μ L is drawn with micropipette rifle
Red bright 6G aqueous solutions are added dropwise after silicon substrate surface, natural evaporation forms the circle that a diameter is about 4mm in silicon substrate surface
The sample prepared is cut the parts 0.5cm × 0.5cm bubble 30min in rhodamine 6G solution, is spent after taking-up by R6G films
Ionized water cleans up, and is dried up at room temperature with nitrogen, is used for Raman spectroscopic detection；
S3, the surface enhanced factor that the Molecular Adsorption signal of absorption on the surface of the substrate is calculated using formula.
2. the computational methods of a kind of preparation and its surface enhanced factor with SERS substrates according to claim 1,
It is characterized in that, the nominal diameter of AAO templates is 25mm in the step S1, aperture 200nm, film thickness are 60 μm.
3. the computational methods of a kind of preparation and its surface enhanced factor with SERS substrates according to claim 1,
It is characterized in that, the surface topography of sample is observed with JSM-7500LV type field emission scanning electron microscopes in the step S1.
4. the computational methods of a kind of preparation and its surface enhanced factor with SERS substrates according to claim 1,
It is characterized in that, the resistivity of ultra-pure water is more than 18M Ω .cm in the step S2-1。
5. the computational methods of a kind of preparation and its surface enhanced factor with SERS substrates according to claim 1,
It is characterized in that, uses the Renishawinvia micro confocal laser Raman spectrometers, excitation wavelength to be in the step S2
785nm, laser output power 1mw, spectral resolution 2cm-1, laser is after 20 times of object lens focus, the hot spot on sample
A diameter of 2 μm, the time 10s of each sample collection spectroscopic data, 950~1850cm of scanning range-1。
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112903655A (en) * | 2021-01-24 | 2021-06-04 | 复旦大学 | Single micro/nano plastic detection method based on Raman spectrum technology |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101097205B1 (en) * | 2010-07-13 | 2011-12-21 | 포항공과대학교 산학협력단 | Fabrication method of substrate for surface enhanced raman scattering |
| CN102590179A (en) * | 2012-03-28 | 2012-07-18 | 上海大学 | Silver nano lattice surface enhanced raman active substrate and preparation method thereof |
| CN103526291A (en) * | 2013-10-28 | 2014-01-22 | 中国工程物理研究院化工材料研究所 | Surface enhanced Raman scattering substrate, preparation method therefor and application thereof |
| KR20170036630A (en) * | 2015-09-23 | 2017-04-03 | 한양대학교 에리카산학협력단 | High-sensitive lateral flow immunoassay strip based on a surface-enhanced raman scattering and method using the same |
| CN107177874A (en) * | 2017-03-27 | 2017-09-19 | 肇庆市华师大光电产业研究院 | A kind of superhigh-density ordered silver nanoparticle ball array and its application |
| WO2017200295A1 (en) * | 2016-05-17 | 2017-11-23 | 충남대학교산학협력단 | Surface-enhanced raman scattering substrate, element for detecting molecule including same, and method for manufacturing same |
-
2018
- 2018-05-28 CN CN201810577529.8A patent/CN108802006A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101097205B1 (en) * | 2010-07-13 | 2011-12-21 | 포항공과대학교 산학협력단 | Fabrication method of substrate for surface enhanced raman scattering |
| CN102590179A (en) * | 2012-03-28 | 2012-07-18 | 上海大学 | Silver nano lattice surface enhanced raman active substrate and preparation method thereof |
| CN103526291A (en) * | 2013-10-28 | 2014-01-22 | 中国工程物理研究院化工材料研究所 | Surface enhanced Raman scattering substrate, preparation method therefor and application thereof |
| KR20170036630A (en) * | 2015-09-23 | 2017-04-03 | 한양대학교 에리카산학협력단 | High-sensitive lateral flow immunoassay strip based on a surface-enhanced raman scattering and method using the same |
| WO2017200295A1 (en) * | 2016-05-17 | 2017-11-23 | 충남대학교산학협력단 | Surface-enhanced raman scattering substrate, element for detecting molecule including same, and method for manufacturing same |
| CN107177874A (en) * | 2017-03-27 | 2017-09-19 | 肇庆市华师大光电产业研究院 | A kind of superhigh-density ordered silver nanoparticle ball array and its application |
Non-Patent Citations (2)
| Title |
|---|
| JIANPING LIN: ""SILVER NANOPARTICLES FILMS DEPOSITED ON AAO TEMPLATES BY THERMAL EVAPORATION FOR SURFACE-ENHANCED RAMAN SCATTERING OF R6G"", 《NANO:BRIEF REPORTS AND REVIEWS》 * |
| 林建平 等: ""真空退火对AAO模板上Ag纳米颗粒膜SERS光谱的影响"", 《宁德师范学院学报（自然科学版）》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112903655A (en) * | 2021-01-24 | 2021-06-04 | 复旦大学 | Single micro/nano plastic detection method based on Raman spectrum technology |
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20181113 |
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| RJ01 | Rejection of invention patent application after publication |