CN108785578A - A kind of topical agent for treating pelvic inflammatory disease - Google Patents

A kind of topical agent for treating pelvic inflammatory disease Download PDF

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Publication number
CN108785578A
CN108785578A CN201811073455.0A CN201811073455A CN108785578A CN 108785578 A CN108785578 A CN 108785578A CN 201811073455 A CN201811073455 A CN 201811073455A CN 108785578 A CN108785578 A CN 108785578A
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radix
rhizoma
blood
inflammatory disease
chinese medicine
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周巧
王晓敏
李霞
杨蕾
桑丽红
孙婷
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Gongan County Hospital Of Traditional Chinese Hospital
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Gongan County Hospital Of Traditional Chinese Hospital
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Abstract

The present invention relates to a kind of topical agents for treating pelvic inflammatory disease, belong to traditional Chinese medicine for external application technical field.It with folium artemisiae argyi, frankincense, myrrh, when being classified as monarch drug in a prescription;Using Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, radix paeoniae rubra, Sargent gloryvine, dandelion, rhizoma cyperi, corydalis tuber, safflower, Radix Notoginseng, dragon's blood, fennel seeds, cassia twig as ministerial drug;Using rhizoma homalonemae, anisetree bark, cortex acanthopanacis, lopseed, smilax, teasel root, Ramulus Taxilli as adjutant;External curing is assisted according to traditional Chinese medicine for pelvic infecton pathogenesis, it is easy to use, do not generate drug resistance, it promotes blood circulation, Medicated Permeation guides drugs to illness station, medication no pain, absorption bleeding, mitigation oedema, improvement local inflammation effect are good, reduce clinical recurrence rate.It solves existing " quadruple chemotherapy ", antibiotic easily makes patient generate drug resistance, Chinese medicine rectally and iontophoresis trouble, pain, and oral traditional Chinese medicine bitter, the impairment of the spleen, and recur after again row " quadruple chemotherapy " therapeutic process, easily there is the problem of physiology and menticide.

Description

A kind of topical agent for treating pelvic inflammatory disease
Technical field
The present invention relates to a kind of topical agents for treating pelvic inflammatory disease, belong to traditional Chinese medicine for external application technical field.
Background technology
The female pelvic cavity inflammatory disease caused by reproductive tract infection includes mainly endometritis, salpingitis, fallopian tubal Ovarian abscess and pelvic peritonitis mostly occur in property active period women after marriage.It is counted according to big data, clinical treatment pelvic infecton is answered Hair rate is up to 25%, and patient suffering is enabled to can't bear, and enables doctor's headache endlessly.Chinese medicine think pelvic infecton mostly due to passing through, sexual intercourse and production Train of thought is hollow afterwards, or the cult poison that has a delicate constitution take advantage of a weak point in opponent's defence in invade, lead to qi depression to blood stasis and onset, acute pelvitis of pelvic cavity with wet poison or it is damp and hot enter Invade as Etiological, use at present injection of antibiotics+Chinese medicine rectally+herbal ion penetration+oral traditional Chinese medicine " tetrad is treated Method " plays certain positive effect to improving clinical acute disease, the shortening course of disease, reducing recurrence.But antibiotic easily makes patient generate Drug resistance, Chinese medicine rectally and iontophoresis trouble, medication process will also result in patient suffering, oral traditional Chinese medicine bitter, The impairment of the spleen, patient's difficulty obtain good efficacy, and are difficult to ensure and no longer recur, once recurrence, it has to repeat controlling for " quadruple chemotherapy " Treatment process causes the huge injury of patient's physiology and psychology, seriously affects the harmonious happy life of entire family.Therefore, very It is necessary to develop one kind in addition to " quadruple chemotherapy ", used according to traditional Chinese medicine diagnosis and treatment based on an overall analysis of the illness and the patient's condition for pelvic infecton pathogenesis It is convenient, drug resistance is not generated, medication process no pain effectively mitigates oedema, absorbs bleeding, hence it is evident that improve local inflammation and micro- follow Ring obstacle, reduces recurrence rate, and auxiliary curative effect treats the topical agent of pelvic inflammatory disease well.
Invention content
It is an object of the present invention in view of the above shortcomings of the prior art, one kind be provided in addition to " quadruple chemotherapy ", for basin Chamber inflammation pathogenesis, it is easy to use according to traditional Chinese medicine diagnosis and treatment based on an overall analysis of the illness and the patient's condition, drug resistance is not generated, is promoted by herbal fomentation Pelvic cavity blood circulation is conducive to absorb inflammatory exudate;Guided drugs to illness station by Medicated Permeation effect, is conducive to softening lesion connective group It knits;Medication process no pain effectively absorbs bleeding and mitigates oedema, hence it is evident that improves local inflammation and microcirculation disorder, auxiliary is treated Effect is fine, and avoiding oral drugs from generating liver to stomach, poison is secondary, stimulation, symptomatic treatment safely, effectively, easily and economically, Greatly reduce the topical agent of the treatment pelvic inflammatory disease of clinical recurrence rate in region.
The present invention is to realize above-mentioned purpose by the following technical solutions:
A kind of topical agent for treating pelvic inflammatory disease, it is characterised in that:It is made up of the Chinese medicine material of following parts by weight:
15~30 radix paeoniae rubra of Radix Angelicae Sinensis, 15~30 safflower, 15~20 dragon's blood 6~9
10~15 Radix Angelicae Pubescentis of Rhizoma Et Radix Notopterygii, 10~15 frankincense, 10~15 myrrh 10~15
20~30 anisetree bark of rhizoma homalonemae, 15~20 cortex acanthopanacis 12~15
15~30 folium artemisiae argyi of lopseed, 15~30 corydalis tuber 20~30
10~20 cassia twig of fennel seeds, 10~15 Radix Notoginseng, 10~15 rhizoma cyperi 15~20
15~30 dandelion of Sargent gloryvine, 20~30 smilax 20~30
15~20 Ramulus Taxilli of teasel root, 20~30 Radix Glycyrrhizae 4~6;
Wherein:
Monarch drug in a prescription is:Folium artemisiae argyi, frankincense, myrrh, Radix Angelicae Sinensis;
Ministerial drug is:Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, radix paeoniae rubra, Sargent gloryvine, dandelion, rhizoma cyperi, corydalis tuber, safflower, Radix Notoginseng, dragon's blood, fennel seeds, cassia twig;
Adjutant is:Rhizoma homalonemae, anisetree bark, cortex acanthopanacis, lopseed, smilax, teasel root, Ramulus Taxilli;
The medicine is set to be:Radix Glycyrrhizae.
A kind of topical agent for treating pelvic inflammatory disease, it is characterised in that:The mass parts of wherein each raw material are:
18 dragon's blood of Radix Angelicae Sinensis 20 radix paeoniae rubra, 20 safflower, 7.5 Rhizoma Et Radix Notopterygii 13
13 folium artemisiae argyi of Radix Angelicae Pubescentis 13 frankincense, 13 myrrh, 20 rhizoma cyperi 18
12.5 Sargent gloryvine of teasel root 18 cassia twig, 12.5 Radix Notoginseng, 20 Radix Glycyrrhizae 6
18 dandelion of Ramulus Taxilli 25 rhizoma homalonemae, 25 anisetree bark, 25 lopseed 20
25 fennel seeds of corydalis tuber, 15 smilax, 25 cortex acanthopanacis 13.5;
It is ground into smalls after each raw material medicaments in part by weight in above-mentioned prescription is weighed, 60 DEG C of warm water are added and are tuned into paste, add White wine mixes well the topical agent for obtaining treatment pelvic inflammatory disease a little, is one per 100g, is coated uniformly on sterile yarn block On, sterile yarn block 1~1.5cm of thickness, when treatment, is covered on patient's lower abdomen, and infrared radiation 30 minutes waits for that sterile yarn is in the block It is removed after topical agent caking of the present invention.
The topical agent of the treatment pelvic inflammatory disease controls method according to differential diagnosis in tcm opinion, for pelvic infecton pathogenesis, The clinical practice of applicant's several years and exploration through the invention using Radix Angelicae Sinensis, radix paeoniae rubra, safflower, dragon's blood, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, frankincense, do not have Medicine, rhizoma cyperi, teasel root, cassia twig, Radix Notoginseng, Sargent gloryvine, Radix Glycyrrhizae, Ramulus Taxilli, rhizoma homalonemae, anisetree bark, dandelion, lopseed, prolongs recklessly at folium artemisiae argyi This 24 taste Chinese herbal medicine combination formula of rope, fennel seeds, smilax, cortex acanthopanacis, promoting blood circulation is safe and efficient, collaterals and relieving pain curative effect Stablize, it is without any side effects, drug resistance is not generated, medication process no pain effectively absorbs bleeding and mitigates oedema, hence it is evident that changes Kind microcirculation, anti-inflammatory analgetic good effect greatly reduce pelvic infecton clinical recurrence rate in region, and 3 months follow-up clinics are multiple after treatment Hair rate from original 32% decline till now 11%.
The property feature of each Chinese medicine material and effect are as follows in instant component:
Radix Angelicae Sinensis:It is sweet in flavor, pungent, warm-natured;Return liver, the heart, the spleen channel;With tonifying blood and regulating menstruation, the effect of promoting blood circulation and stopping pain, moisturize laxation.《Book on Chinese herbal medicine Detailed outline》It says:" head stops blooding and uplink;Body, blood-nourishing and in keep;The tip, blood-breaking and flow down;Entirely, promoting blood circulation is without walking ".
Radix paeoniae rubra:Bitter is slightly cold, return liver warp, can clearing heat and cooling blood, removing blood stasis and analgesics;《Sheng Nong's herbal classic》:" main perverse trend abdominal pain, is removed Blood-arthralgia breaks hard product, fever and chills hernia lump in the abdomen, analgesic, diuresis ".
Safflower:It is pungent, warm.Converge to heart and liver channels.Invigorate blood circulation, stasis-dispelling and pain-killing.《Collected statements on the herbal foundation》:" safflower, blood-breaking, promoting circulation of blood and Blood, the medicine for adjusting blood ".
Dragon's blood:Sweet, salty, flat, converge to heart and liver channels, can invigorate blood circulation analgesic therapy, removing blood stasis and hemostasis, expelling pus and promoting granulation.《This is through meeting original》:It " cures the wound Folding, which is beaten, damages all pain, and vim and vigour stir thorn, and interior blood trouble is poly- ..., and this is then specially in Liver Channel blood system ".
Rhizoma Et Radix Notopterygii:Acrid flavour, hardship, it is warm-natured.Return bladder;Kidney channel.Effect dissipates exterior cold, wind-damp dispelling, sharp joint, analgesic.《Herbal guiding principle Mesh》:" after Qiang, Radix Angelicae Pubescentis, all can close profit section thoroughly by wind prevailing over dampness, but gas have it is just bad it is different you ".
Radix Angelicae Pubescentis:Acrid flavour, hardship, slightly warm in nature.Return kidney, bladder warp.Effect dispelling wind and eliminating dampness, arthritis analgesic.《Collected statements on the herbal foundation》:" solely It is living, benefaction blood system, the medicine of the wet cold dispelling of wind-dispelling row.The card of all disease wind, if head term is unable to pitching, waist and knee cannot be bent and stretched or numbness pain It is difficult to walk, numbness does not have to, all wind and cold caused, heat and wet institute's wound;Must be warm with the toil of Radix Angelicae Pubescentis, movable qi and blood is dispelled scattered Cold-evil ".
Frankincense:It is pungent, bitter, temperature;The thoughts of returning home, liver, the spleen channel.Effect blood-activating and qi-promoting relieves pain, detumescence and promoting granulation.《Collected statements on the herbal foundation》:" breast Perfume (or spice), promoting blood circulation by removing wind, the medicine of relaxing muscles and tendons analgesic.... and fall servant's bucket and beat, injured muscles and bones, but postpartum qi and blood attacks thorn, and trusted subordinate's pain is permanent With this, it is salty take its it is fragrant it is pungent wander away, dissipate blood apocenosis, ventilationization is stagnant for special work(".
Myrrh:Acrid flavour, hardship, it is mild-natured.The thoughts of returning home, liver, the spleen channel.Effect scattered stasis pain, detumescence and promoting granulation.《Book on Chinese herbal medicine is stated》:" long term usage Relaxing muscles and tendons film, promoting blood circulation, permanent tooth tooth, long beard and hair ".
Rhizoma homalonemae:Taste acrid, bitter, warm returns liver and kidney channel, major function wind-damp dispelling, muscle reinforcing and bone strengthening, promoting blood circulation and stopping pain.《Book on Chinese herbal medicine is just Justice》:Rhizoma homalonemae, modern perseverance are used for ventilation meridian, and wind-dispelling quite has confirmed by numbness.Lid smell is all thick, and also pungent-warm walks the effect altered ?.
Anisetree bark:Pharmacological property:Temperature.Flavour of a drug:It is micro-pungent, puckery.Channel tropism:Return bladder warp, kidney channel.Function:Dispelling wind and eliminating dampness, promoting the circulation of qi stop Bitterly.《National Chinese herbal medicine compilation》:" relaxing tendons and activating collaterals, expelling wind and activating blood flow.Rheumatalgia is cured mainly, extremities joint is ached ".
Cortex acanthopanacis:Taste acrid, bitter, warm, returns liver and kidney channel, there is wind-damp dispelling, tonifies the liver and kidney, and strengthens muscles and bones, the work of inducing diuresis for removing edema With.《Compendium of Materia Medica》:" main impotence, harmful wind hurts sb.'s feelings, and weak foot waist removes hemostasis for many years ".
Lopseed:Acrid flavour, it is warm-natured, enter liver and kidney channel.There are dispelling wind and eliminating dampness, relaxing tendons and activating collaterals, eliminating stasis to subdue swelling, the work(for analgesic of detoxifying Effect.《Detailed outline》:" control muscles and bones all rheumatism, pain contracture, the disturbance of lower legs due to pathogenic cold and dampness."《Shandong Chinese herbal medicine handbook》:" wind-damp dispelling, promoting blood circulation, only Bitterly ".
Folium artemisiae argyi:It is pungent, bitter, temperature.Return liver, spleen, kidney channel.Effect:Warming channel for arresting bleeding, eliminating cold to stop pain;External application removing dampness to stop itchin.《Book on Chinese herbal medicine From new》:" expelling cold-dampness, warm up uterus, only all blood, middle benefit gas open strongly fragrant, menstruation regulating tocolysis ".
Corydalis tuber:It is pungent, bitter, temperature.Return liver, the spleen channel.Effect:Promoting blood circulation, promoting the circulation of qi, analgesic.《Compendium of Materia Medica》:" the sharp gas of promoting blood circulation, only Bitterly, diuresis." 《This is through meeting original》:" corydalis tuber color Huang enters taste, and energy promoting blood circulation and stopping pain controls small blood of urinating and defecating.It obtains excrementum pteropi and enters liver together It is broken through scattered blood stagnant ".
Fennel seeds:Acrid flavour, it is warm-natured.Return liver,kidney,spleen, stomach.There is the effect of eliminating cold to stop pain, regulating qi-flowing for harmonizing stomach.《Book on Chinese herbal medicine converges Speech》:" medicine of the fast gas of middle benefit gas ".
Cassia twig:Acrid, sweet, warm enter lung, the heart, bladder warp.Effect:Sweating expelling pathogenic factors from muscles and skin, warming meridian, helps yang transforming qi.《Changsha medicine Solution》:" cassia twig, enters liver man and promoting circulation of blood divides, and walks channels and collaterals and reaches Rong Yu.Kind solution ailment said due to cold or exposure, most adjusts wood gas.Turbid yin drops in the detrapping of sending up the lucid YANG Rush inverse, the urgency contraction of relaxing muscles and tendons arteries and veins, the heap soil or fertilizer over and around the roots resistance in sharp joint.Enter liver and gall and dissipate and suppress, pole relieves pain Chu, degrading the channel and to open numbness puckery, very go It is raw.Run quickly globefish, more peace palpitation with fear can be stopped ".
Radix Notoginseng:Sweet, slight bitter, temperature.Return liver, stomach.Effect:Dissipate stasis of blood hemostasis, detumescence ding-tong.《Compendium of Materia Medica》:Styptic powder blood Analgesic therapy, golden sword arrow wound, fall flutter cane sore, blood goes out more than person, chews rotten painting, or mix it for end, blood is i.e. only.Also main hematemesis and epistaxis, under Blood bloody flux, metrorrhagia incessant menorrhea, postpartum extravesated blood not under, blood transports blood pain, and Akamu carbuncle swells, tiger stings all diseases of snakebite.
Rhizoma cyperi:Pungent, slight bitter, micro- sweet and neutral.Return liver, spleen, tri-jiao channel.Effect:Soothing liver-qi stagnation, regulating the flow of QI to ease the stomach, menstruction regulating and pain relieving. 《Detailed outline》:" gas of rhizoma cyperi is flat without cold, fragrant and can alter, and how pungent taste is can dissipate, and slight bitter can drop, micro-sweet energy with.Raw then uplink chest Diaphragm reaches skin outside, ripe, under walk liver kidney, outer thorough waist foot ".
Sargent gloryvine:Bitter, it is mild-natured.Return large intestine, Liver Channel.Have removing toxicity for eliminating carbuncles, promoting blood circulation and stopping pain, dispelling wind and eliminating dampness, disinsection efficiency.《In Medicine will》:" wind-dispelling degrading the channel, diuresis desinsection.Control acute appendicitis, arthralgia pain due to rheumatism, leprosy, gonorrhoea, roundworm abdominal pain ".
Dandelion:Bitter sweet is trembled with fear.Enter liver, stomach.Effect:It is clearing heat and detoxicating, diuresis dissipating bind.《A supplement to augmented materia medica》:" change heat Poison, the swollen tuberculosis of the evil that disappears, Detoxicating food-poisoning dissipate stagnant gas ".
Smilax:It is sweet, light, it puts down.Return liver, stomach.Effect:Removing toxic substances, dehumidifying is easing joint movement.《Compendium of Materia Medica》:" strengthening the spleen and stomach, Strengthening the bones and muscles, curing rheumatism, sharp joint, stopping leak rush down ".
Teasel root:Bitter, pungent, slightly warm in nature.Return liver, kidney channel.Effect:Blood vessels, only uterine bleeding are adjusted in filling liver kidney, strengthening the bones and muscles.《The southern regions of the Yunnan Province Book on Chinese herbal medicine》:Tonifying liver, strengthening the bones and muscles walk channels and collaterals, in only passing through(Muscles and bones)Ache, tocolysis controls married woman leukorrhea, raw new blood, and broken stasis of blood blood is fallen dead A word used in place name, cough-relieving are coughed hemoptysis, and red white turbid urine is controlled.
Ramulus Taxilli:Bitter sweet and neutral.Enter liver and kidney channel.Effect:Filling liver kidney, strengthening the bones and muscles, curing rheumatism, degrading the channel, beneficial blood, tocolysis. 《This is through meeting original》:The residual air of parasitic mulberry and give birth to, the special wind-dispelling of property leads to and adjusts blood vessels by wet, therefore《This warp》It takes and controls married woman's pain in the back, children The diseases such as the back of the body is strong, Xuemaitong tune and skin eyebrow must have carbuncle swells, must also dissipate all by its shade.
Radix Glycyrrhizae:It is sweet in flavor, it is mild-natured.The thoughts of returning home, lung, spleen, stomach.Effect:It invigorates the spleen and benefits qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, emergency is stopped Bitterly, coordinating the drug actions of a prescription.《Collected statements on the herbal foundation》:Radix Glycyrrhizae and middle QI invigorating, the medicine of qi-restoratives removing toxic substances.Strengthening the spleen and stomach, Gu the void of middle gas is thin, association is cloudy Sun and uncomfortable battalion defend.Therefore strain internal injury is controlled, deficiency-weakness of spleen-QI, first YANG deficiency, lung qi declines void, and Gan Wenping is mended, effect and ginseng, stilbene And.
The advantageous effect of the present invention compared with prior art is:
The topical agent of the treatment pelvic inflammatory disease, with folium artemisiae argyi, frankincense, myrrh, when being classified as monarch drug in a prescription;With Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, red Chinese herbaceous peony, Sargent gloryvine, dandelion, rhizoma cyperi, corydalis tuber, safflower, Radix Notoginseng, dragon's blood, fennel seeds, cassia twig are ministerial drug;With rhizoma homalonemae, anisetree bark, Cortex acanthopanacis, lopseed, smilax, teasel root, Ramulus Taxilli are adjutant;It is to make medicine with Radix Glycyrrhizae;Coordinate " quadruple chemotherapy " that specific aim is unfolded External curing is assisted, it is without any side effects, drug resistance is not generated, medication process no pain, treatment is very easy to use, effectively It absorbs bleeding and mitigates oedema, promoting blood circulation is safe and efficient, collaterals and relieving pain good effect, hence it is evident that improves microcirculation disorder, greatly The big recurrence rate for reducing pelvic infecton in region, 3 months follow-up clinical recurrence rates decline till now from original 32% after treatment 11%.It solves existing " quadruple chemotherapy ", antibiotic easily makes patient generate drug resistance, Chinese medicine rectally and iontophoresis Trouble, medication process cause patient suffering, and oral traditional Chinese medicine bitter, the impairment of the spleen, and patient's difficulty obtains good efficacy, and is difficult to ensure not It recurs again, and repeats " quadruple chemotherapy " therapeutic process, so that patient the problem of physiology and menticide is occurred, become Chinese medicine Capable " assistant " of clinical treatment pelvic infecton relapse.
Specific implementation mode
The embodiment of the topical agent of the treatment pelvic inflammatory disease is described in further detail below:
A kind of topical agent for treating pelvic inflammatory disease, it is characterised in that:It is the Chinese medicine material system by following parts by weight At:
15~30 radix paeoniae rubra of Radix Angelicae Sinensis, 15~30 safflower, 15~20 dragon's blood 6~9
10~15 Radix Angelicae Pubescentis of Rhizoma Et Radix Notopterygii, 10~15 frankincense, 10~15 myrrh 10~15
20~30 anisetree bark of rhizoma homalonemae, 15~20 cortex acanthopanacis 12~15
15~30 folium artemisiae argyi of lopseed, 15~30 corydalis tuber 20~30
10~20 cassia twig of fennel seeds, 10~15 Radix Notoginseng, 10~15 rhizoma cyperi 15~20
15~30 dandelion of Sargent gloryvine, 20~30 smilax 20~30
15~20 Ramulus Taxilli of teasel root, 20~30 Radix Glycyrrhizae 4~6;
Wherein:
Monarch drug in a prescription is:Folium artemisiae argyi, frankincense, myrrh, Radix Angelicae Sinensis;
Ministerial drug is:Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, radix paeoniae rubra, Sargent gloryvine, dandelion, rhizoma cyperi, corydalis tuber, safflower, Radix Notoginseng, dragon's blood, fennel seeds, cassia twig;
Adjutant is:Rhizoma homalonemae, anisetree bark, cortex acanthopanacis, lopseed, smilax, teasel root, Ramulus Taxilli;
The medicine is set to be:Radix Glycyrrhizae.
A kind of topical agent for treating pelvic inflammatory disease, it is characterised in that:The mass parts of wherein each raw material are:
18 dragon's blood of Radix Angelicae Sinensis 20 radix paeoniae rubra, 20 safflower, 7.5 Rhizoma Et Radix Notopterygii 13
13 folium artemisiae argyi of Radix Angelicae Pubescentis 13 frankincense, 13 myrrh, 20 rhizoma cyperi 18
12.5 Sargent gloryvine of teasel root 18 cassia twig, 12.5 Radix Notoginseng, 20 Radix Glycyrrhizae 6
18 dandelion of Ramulus Taxilli 25 rhizoma homalonemae, 25 anisetree bark, 25 lopseed 20
25 fennel seeds of corydalis tuber, 15 smilax, 25 cortex acanthopanacis 13.5.
The research and development thought of present invention applicant is as follows:
Present invention applicant works in the Hubei Province Gongan County domain hospital of traditional Chinese hospital throughout the year, touches a large amount of female pelvic cavity inflammatory disease Recurrent exerbation patient often results in sequelae, to sufferers themselves and family because frightened therapeutic process or dislike trouble due to postpone diagnosis and treatment Front yard and fertility offspring cause greatly to perplex.Doctor trained in Western medicine is to treating female pelvic cavity inflammatory disease at present(PID)It there is no definite effective Therapeutic scheme mainly carries out anti-inflammatory treatment using antibiotic, uses injection of antibiotics+Chinese medicine rectally+tcm herbal ion at present " quadruple chemotherapy " of importing+oral traditional Chinese medicine, although to improve clinical acute disease, shorten the course of disease, reduce recurrence play it is certain positive Effect, but antibiotic easily makes patient generate drug resistance, and Chinese medicine rectally and iontophoresis trouble, medication process can also be made At patient suffering, oral traditional Chinese medicine bitter, the impairment of the spleen, patient's difficulty obtains good efficacy, and is difficult to ensure and no longer recurs, once recurrence, The therapeutic process for repeating " quadruple chemotherapy " causes the huge injury of patient's physiology and psychology, seriously affects the harmony happiness of family Life.Therefore present invention applicant treats advantage according to Chinese medicine, in addition to using " quadruple chemotherapy ", focuses on Chinese medicinal external application treatment, whole Body is combined with part, righting with getting rid of evils, and is led to regulating the qi flowing in the channels blood punching and is appointed, righting is not forgotten in eliminating evil, develops the treatment pelvic inflammatory disease Topical agent, it is very easy to use, promoted treated effect, shorten paresthesia alleviateding time, greatly reduce recurrence rate, effectively It avoids and the side effect that antibiotic is brought is used for a long time, it is deep to be praised by patient.
In the prescription of the topical agent of the treatment pelvic inflammatory disease, folium artemisiae argyi, frankincense, myrrh, dragon's blood, anisetree bark, safflower, Radix Notoginseng can promoting blood circulation and removing blood stasis, eliminating stagnation to stop pain, to the targeted therapeutic effect of qi depression to blood stasis;Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, radix paeoniae rubra, Sargent gloryvine, Pu Gong English, smilax can clearing heat and promoting diuresis, stasis-dispelling and pain-killing, have good therapeutic effect to Accumulation of Dampness Heat and Blood Stasis;Fennel seeds, key in thousand, lopseed, Cassia twig dispelling cold and removing dampness, stasis-dispelling and pain-killing, stagnating to cold-dampness has therapeutic effect;Teasel root, Radix Angelicae Sinensis, Ramulus Taxilli, cortex acanthopanacis replenish qi to invigorate the spleen The effect of kidney tonifying, blood-activating analgetic, plays therapeutic effect for qi deficiency to blood stasis.The present invention treats the topical agent of pelvic inflammatory disease, With traditional Chinese medicine, it with strong odor medicinal material folium artemisiae argyi, frankincense, myrrh and ought be classified as guiding, lead comedicine opening block and activating stagnancy straight Up to lesion.Skin can be penetrated and generate promoting blood circulation and removing blood stasis, clearing and activating the channels and collaterals, swelling and pain relieving and wind-expelling and cold-expelling efficacy.Spread on somatic stimulation god Through tip, blood vessel is expanded, promotes local blood circulation, improves surrounding tissue nutrition, reaches detumescence, anti-inflammatory and analgesic purpose; The drug of the topical agent of the pelvic inflammatory disease of present invention treatment simultaneously infiltrates into subcutaneous tissue by patient skin, makes patient office Portion's subcutaneous tissue converges high concentration medicine, plays the accurate therapeutic effect of targeting of drug to greatest extent.
The effect of in order to illustrate the present invention to treatment female pelvic cavity inflammatory disease, by 280 basins of the first half of the year in 2018 The clinical observation of chamber inflammation patient, clinical data are as follows:
1), general data:The pelvic inflammatory disease PID patient 280 that Nian8Yue our hospital in January, 2018~2018 accepts for medical treatment is chosen, In the case of medical patient's informed consent, medical patient is divided into control group and observation group, each 140.Control group average age (31.5±14.1)Year, average course of disease:(3.6±2.1)Year;Observation group's average age(30.4±17.5)Year, average course of disease (3.4±2.4)Year.Two groups of patient's general information compare, no significant difference(P > 0.05).
2), inclusion criteria
1. hypogastralgia and waist and sacrum pain, after sexual intercourse, when tired, defecation or menstruation is front and back aggravates;
2. profuse leukorrhea, irregular menstruation, infertile;
3. the mostly rear position in uterus, gynaecological examination limitation of activity, palace side tissue sheet thickens or fallopian tubal thickening, tenderness or pelvic cavity side or two There are capsule, inactive mass in side;
4. it does not recover for a long time, recurrent exerbation.
3), therapy
Control group uses antibiosis extract for treating, patient to use cefobutazine sodium 2g q12h+Tinidazole 0.4g qd intravenous drips, Continue 10 days.
Observation group in addition to the above-mentioned antiphlogistic of intravenous infusion, using the present invention treatment pelvic inflammatory disease topical agent to patient outside Lower abdomen is applied, infra-red light irradiation is aided with, 2 times a day, 30 minutes/time continue 10 days, after 3 menstrual cycles of continued treatment, into Row therapeutic evaluation.
4), efficacy assessment standard:
After 3 menstrual cycle courses for the treatment of, evaluate two groups of patients the effect of, compare the treated effect of two groups of patients;To curing Its recurrence rate is observed in patient's follow-up 3 months afterwards.
It cures:Refer to feeling to ache without hypogastralgia and lumbosacral region, gynaecological examination, without tenderness, B ultrasound prompts basin for uterus and double accessory Chamber inflammatory lesion is clearly better or disappears.
Effectively:Feel that hypogastralgia and waist sacrum are ached symptom mitigation, gynaecological examination uterus and the light tenderness of double accessory, B ultrasound prompt:Pelvic cavity Inflammatory lesion or adhesion improving situation.
In vain:Patient feels that hypogastralgia and lumbosacral region malaise symptoms are not improved, and gynaecological examination uterus and double accessory tenderness are still More apparent, B ultrasound prompt pelvic inflammatory lesion does not improve.
Treated effect is equal to cure rate added with efficiency.
5), curative effect comparison sheet 1
6), recurrence comparison sheet 2
As can be seen from Table 1 and Table 2:Control group is with observation group in total effective rate, paresthesia alleviateding time, recurrence time, recurrence rate It is upper that there were significant differences.
It is model case below:
Patient Chen, female, 42 years old, because " lower abdominal distention pain is ached two months with waist sacrum, aggravates half a month " is admitted to hospital in 2018-01-21.It is flat Bright and clear moon is through rule, and amount is medium, and color is dark red, and no clot has premenstrual swollen breasts.There is lower abdominal distention pain companion without apparent inducement before two months Waist sacrum is ached, and is alleviated after rest, tired postemphasis, and above-mentioned symptom was felt before half a month and is aggravated, until outer court is medical, to give drug intravenous infusion anti-inflammatory After one week treatment is without improvement(Clindamycin 1.2g/d), gone to a doctor then in Gong'an Chinese Medicine Hospital, Hubei Prov., outpatient service is with " pelvic inflammatory disease Admit to hospital disease " treatment.
Human health screening, vital sign is normal, and pale tongue is purple, and tongue is thin, and wiry and rolling pulse, abdomen is flat, lower abdomen tenderness, no Blumberg's sign.
Training inspection:Retroposition of uterus, normal size, tenderness(+), activity can, ride side attachment area tenderness is apparent.
Auxiliary examination:Outer court's 2018-01-17 B ultrasound is shown:Ride side attachment tumour(Size about 22 × 25mm), Tao Shi chambers Hydrops 20mm.
Tcm diagnosis:Married woman's abdominal pain-qi stagnation and blood stasis type doctor trained in Western medicine diagnosis:Pelvic inflammatory disease.
Treatment:Cefobutazine sodium, Tinidazole intravenous drip are given, oral traditional Chinese medicine Sargent gloryvine soup bowel lavage and traditional Chinese herbal decoction are oral, this The topical agent of invention treatment pelvic inflammatory disease is externally applied to patient abdomen, infra-red light irradiation, after 3 days patient's self-induction abdominal pain and The symptoms were significantly improved for pain in the back, and symptom disappears after a week, and 2018-01-28 check B ultrasound is shown:Uterus and double accessory have no apparent different Often, Tao Shi chambers hydrops 5mm, continuous treatment are left hospital after 10 days.It is paid a return visit after discharge half a year, pelvic infecton is without recurrence.
The above is presently preferred embodiments of the present invention, and the example above illustrates that the substantive content not to the present invention is made Limitation in any form, technology of the person of an ordinary skill in the technical field after having read this specification according to the present invention Essence is to any simple modification or deformation made by the above specific implementation mode, and the technology contents possibly also with the disclosure above The equivalent embodiment for being changed or being modified to equivalent variations, in the range of still falling within technical solution of the present invention, without departing from The spirit and scope of the invention.

Claims (2)

1. a kind of topical agent for treating pelvic inflammatory disease, it is characterised in that:It is the Chinese medicine material by following parts by weight It is manufactured:
15~30 radix paeoniae rubra of Radix Angelicae Sinensis, 15~30 safflower, 15~20 dragon's blood 6~9
10~15 Radix Angelicae Pubescentis of Rhizoma Et Radix Notopterygii, 10~15 frankincense, 10~15 myrrh 10~15
20~30 anisetree bark of rhizoma homalonemae, 15~20 cortex acanthopanacis 12~15
15~30 folium artemisiae argyi of lopseed, 15~30 corydalis tuber 20~30
10~20 cassia twig of fennel seeds, 10~15 Radix Notoginseng, 10~15 rhizoma cyperi 15~20
15~30 dandelion of Sargent gloryvine, 20~30 smilax 20~30
15~20 Ramulus Taxilli of teasel root, 20~30 Radix Glycyrrhizae 4~6;
Wherein:
Monarch drug in a prescription is:Folium artemisiae argyi, frankincense, myrrh, Radix Angelicae Sinensis;
Ministerial drug is:Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, radix paeoniae rubra, Sargent gloryvine, dandelion, rhizoma cyperi, corydalis tuber, safflower, Radix Notoginseng, dragon's blood, fennel seeds, cassia twig;
Adjutant is:Rhizoma homalonemae, anisetree bark, cortex acanthopanacis, lopseed, smilax, teasel root, Ramulus Taxilli;
The medicine is set to be:Radix Glycyrrhizae.
2. a kind of topical agent for treating pelvic inflammatory disease according to claim 1, it is characterised in that:Wherein each raw material Mass parts be:
18 dragon's blood of Radix Angelicae Sinensis 20 radix paeoniae rubra, 20 safflower, 7.5 Rhizoma Et Radix Notopterygii 13
13 folium artemisiae argyi of Radix Angelicae Pubescentis 13 frankincense, 13 myrrh, 20 rhizoma cyperi 18
12.5 Sargent gloryvine of teasel root 18 cassia twig, 12.5 Radix Notoginseng, 20 Radix Glycyrrhizae 6
18 dandelion of Ramulus Taxilli 25 rhizoma homalonemae, 25 anisetree bark, 25 lopseed 20
25 fennel seeds of corydalis tuber, 15 smilax, 25 cortex acanthopanacis 13.5;
It is ground into smalls after each raw material medicaments in part by weight in above-mentioned prescription is weighed, 60 DEG C of warm water are added and are tuned into paste, add White wine mixes well the topical agent for obtaining treatment pelvic inflammatory disease a little, is one per 100g, is coated uniformly on sterile yarn block On, sterile yarn block 1~1.5cm of thickness, when treatment, is covered on patient's lower abdomen, and infrared radiation 30 minutes waits for that sterile yarn is in the block It is removed after topical agent caking of the present invention.
CN201811073455.0A 2018-09-14 2018-09-14 A kind of topical agent for treating pelvic inflammatory disease Pending CN108785578A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112315945A (en) * 2020-11-13 2021-02-05 云南省第一人民医院 External application traditional Chinese medicine composition for treating gynecological diseases, transdermal drug delivery patch and application
CN113144161A (en) * 2021-04-21 2021-07-23 柳州市中医医院(柳州市壮医医院) Chinese medicinal composition for treating pelvic inflammation and hydrops

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Publication number Priority date Publication date Assignee Title
CN103006960A (en) * 2012-12-05 2013-04-03 姜晶 Traditional Chinese medicine hot compress bag for curing gynecologic abdominal mass and preparation method of traditional Chinese medicine hot compress bag
CN107397936A (en) * 2017-07-26 2017-11-28 荆门市第二人民医院 A kind of Chinese prescription for treating chronic pelvic inflammatory disease
CN108186839A (en) * 2018-03-16 2018-06-22 广州欧盛化妆品有限公司 A kind of hot compress agent for treating pelvic infecton and its hot compress method

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103006960A (en) * 2012-12-05 2013-04-03 姜晶 Traditional Chinese medicine hot compress bag for curing gynecologic abdominal mass and preparation method of traditional Chinese medicine hot compress bag
CN107397936A (en) * 2017-07-26 2017-11-28 荆门市第二人民医院 A kind of Chinese prescription for treating chronic pelvic inflammatory disease
CN108186839A (en) * 2018-03-16 2018-06-22 广州欧盛化妆品有限公司 A kind of hot compress agent for treating pelvic infecton and its hot compress method

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112315945A (en) * 2020-11-13 2021-02-05 云南省第一人民医院 External application traditional Chinese medicine composition for treating gynecological diseases, transdermal drug delivery patch and application
CN113144161A (en) * 2021-04-21 2021-07-23 柳州市中医医院(柳州市壮医医院) Chinese medicinal composition for treating pelvic inflammation and hydrops
CN113144161B (en) * 2021-04-21 2022-02-22 柳州市中医医院(柳州市壮医医院) Externally applied traditional Chinese medicine composition for treating pelvic inflammation and pelvic effusion

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