CN108754741A - Used in tissue engineering biomimetic type trachea bracket - Google Patents
Used in tissue engineering biomimetic type trachea bracket Download PDFInfo
- Publication number
- CN108754741A CN108754741A CN201810532057.4A CN201810532057A CN108754741A CN 108754741 A CN108754741 A CN 108754741A CN 201810532057 A CN201810532057 A CN 201810532057A CN 108754741 A CN108754741 A CN 108754741A
- Authority
- CN
- China
- Prior art keywords
- layer
- outer layer
- circumferential
- middle layer
- tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- D—TEXTILES; PAPER
- D03—WEAVING
- D03D—WOVEN FABRICS; METHODS OF WEAVING; LOOMS
- D03D3/00—Woven fabrics characterised by their shape
- D03D3/02—Tubular fabrics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
-
- D—TEXTILES; PAPER
- D03—WEAVING
- D03D—WOVEN FABRICS; METHODS OF WEAVING; LOOMS
- D03D11/00—Double or multi-ply fabrics not otherwise provided for
- D03D11/02—Fabrics formed with pockets, tubes, loops, folds, tucks or flaps
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Textile Engineering (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Materials For Medical Uses (AREA)
- Woven Fabrics (AREA)
- Prostheses (AREA)
Abstract
The present invention relates to a kind of used in tissue engineering biomimetic type trachea brackets, including outer layer, middle layer and internal layer, outer layer and internal layer are the tissue that average float is less than or equal to 2, middle layer is the tissue that average float is more than 2, outer layer, middle layer and internal layer form tubing by stitch weave and wefting insertion, middle layer and internal layer circumferential cross-section are in O-shaped, outer layer circumferential cross-section is C-shaped, axially spaced several circumferential passageways is distributed with, the circumferential passageway of outer layer is protruded with intermediate layer separation, and the circumferential passageway of outer layer is double width fabric construction.The present invention realizes the integrated weaving in trachea bracket three-layer pipe road, overall structure is uniform and stable, sufficient support can be provided for the regeneration and reconstruction of tracheae diseased region, be conducive to the placement of tracheal rings, good architecture basics can be provided for the reparation and establishment of tracheal rings, be suitable for continuous production.
Description
Technical field
The invention belongs to the technical fields of trachea bracket, more particularly to a kind of used in tissue engineering biomimetic type trachea bracket.
Background technology
In recent years, organizational project by holder guide tissue regeneration and controls the structure and function of tissue in trachea bracket,
As the research hotspot of related discipline.Tracheae is a part for respiratory apparatus, and tube wall is in slightly flat cylindric.Tracheal wall by outside to
It is inside fiber and muscle layer, fibrocartilage layer and submucosa respectively, innermost layer is mucous layer, in an axial direction by 14-16 semi-ring
Shape " C " font cartilage is constituted, and each cartilaginous ring is by tough band connection.The present invention " is segmented fusion to be oriented derived from what clinical demand proposed
Bone remoulding Long bone defect " is theoretical, in conjunction with the cognition to person's windpipe anatomical features, can integrated molding prepare with week
To the woven trachea bracket of biomimetic type used in tissue engineering of pipeline.
Invention content
Technical problem to be solved by the invention is to provide a kind of used in tissue engineering biomimetic type trachea brackets, realize biomimetic type
The integrated weaving in trachea bracket three-layer pipe road, overall structure are uniform and stable.
The technical solution adopted by the present invention to solve the technical problems is to provide a kind of used in tissue engineering biomimetic type rami tracheales
Frame, including outer layer, middle layer and internal layer, the outer layer and internal layer are the tissue that average float is less than or equal to 2, and the middle layer is
Average float is more than 2 tissue, and the outer layer, middle layer and internal layer form tubing by stitch weave and wefting insertion, described
Middle layer and internal layer circumferential cross-section in O-shaped, the outer layer circumferential cross-section is C-shaped, it is axially spaced several circumferential passageways are distributed with,
The circumferential passageway of the outer layer is protruded with intermediate layer separation, and the circumferential passageway of the outer layer is double width fabric construction.
The back warp stitch weave structure that itself stitch weave between the outer layer, middle layer and internal layer connects under being.
Two circumferential passageways are distributed on the trachea bracket in an axial direction.
The outer layer and internal layer are weaved using monofilament, and the middle layer is weaved using multifilament.
Advantageous effect
Overall structure of the present invention is uniform and stable, has excellent radial support power and good elastic recovery, can be
The regeneration of tracheae diseased region and the support that offer abundance is provided；Circumferential cross-section of the present invention is C-shaped, axially spaced-apart distribution is circumferential logical
The structure in road is conducive to the placement of tracheal rings, can provide good structure base for the reparation and establishment of tracheal rings
Plinth；The present invention realizes the integrated weaving in trachea bracket three-layer pipe road, is suitable for continuous production.
Description of the drawings
Fig. 1 is the structural diagram of the present invention.
Fig. 2 is the basic organization figure of outer layer of the embodiment of the present invention.
Fig. 3 is the basic organization figure of middle layer of the embodiment of the present invention.
Fig. 4 is the basic organization figure of internal layer of the embodiment of the present invention.
Fig. 5 is the arrangement of three-layer pipe shape fabric warp of the embodiment of the present invention and wefting insertion order schematic diagram.
Fig. 6 is the drafting plan of the embodiment of the present invention.
Fig. 7 is the organization chart of three layers of binding part of the embodiment of the present invention.
Fig. 8 is the organization chart of circumferential direction pipe section of the embodiment of the present invention.
Specific implementation mode
Present invention will be further explained below with reference to specific examples.It should be understood that these embodiments are merely to illustrate the present invention
Rather than it limits the scope of the invention.In addition, it should also be understood that, after reading the content taught by the present invention, people in the art
Member can make various changes or modifications the present invention, and such equivalent forms equally fall within the application the appended claims and limited
Range.
A kind of used in tissue engineering biomimetic type trachea bracket as shown in Figure 1, including outer layer 1, middle layer 2 and internal layer 3.Outer layer
1 selects 1/2 twill-weave, as shown in Fig. 2, outer layer 1 is used as using the PDO monofilament of a diameter of 0.2mm weaves material.Middle layer 2
1/5 twill-weave is selected, is woven as shown in figure 3, middle layer 2 uses specification to be used as the PHBV/PLA multifilament of 160dtex/72f
Material.Internal layer 3 selects 2/1 twill-weave, as shown in figure 4, internal layer 3 is used as using the PDO monofilament of a diameter of 0.2mm weaves material
Material.
The internal diameter of the trachea bracket is 15mm, and breadth is designed as 32.5mm on the machine of tubing, other set factors are such as
Shown in the following table 1.
The weaving parameters of 1 trachea bracket of table
Outer layer 1, middle layer 2 and internal layer 3 combine " by outer and interior " again by the back warp tying method binding of " under connect "
" from inside to outside " filling insertion way forms monoblock type tubing by the reasonable selection to wefting insertion order parameters.Wherein, in
The circumferential cross-section of interbed 2 and internal layer 3 is in O-shaped, and 1 circumferential cross-section of outer layer is C-shaped, axially spaced distribution is there are two circumferential passageway 4,
The circumferential passageway 4 of outer layer 1 detaches protrusion with middle layer 2, and the circumferential passageway 4 of outer layer 1 is double width fabric construction.
Outer layer 1, the warp thread of middle layer 2 and internal layer 3, weft yarn arrangement ratio are respectively 1:2:1 and 2:4:2.Tubing warp thread
Arrangement and wefting insertion order are as shown in Figure 5.The drafting plan of the present embodiment design is as shown in Figure 6, wherein the 1st, 2,3,22,23,24 is comprehensive
Frame penetrates 1 warp thread of outer layer；4th, 5,6,7,8,9,16,17,18,19,20,21 heald frames penetrate 2 warp thread of middle layer；10th, 11,
12,13,14,15 heald frames penetrate 3 warp thread of internal layer.Such as Fig. 7 institutes of fabric organization chart of three layers of binding part 5 of the present embodiment design
Show, the fabric organization chart of 4 part of circumferential pipeline is as shown in Figure 8.
Claims (4)
1. a kind of used in tissue engineering biomimetic type trachea bracket, including outer layer (1), middle layer (2) and internal layer (3), it is characterised in that：
The outer layer (1) and internal layer (3) are the tissue that average float is less than or equal to 2, and the middle layer (2) is average float more than 2
Tissue, the outer layer (1), middle layer (2) and internal layer (3) form tubing, the middle layer by stitch weave and wefting insertion
(2) and internal layer (3) circumferential cross-section is in O-shaped, and outer layer (1) circumferential cross-section is C-shaped, axially spaced that several circumferential directions are distributed with is logical
The circumferential passageway (4) in road (4), the outer layer (1) detaches protrusion with middle layer (2), and the circumferential passageway (4) of the outer layer (1) is
Double width fabric construction.
2. a kind of used in tissue engineering biomimetic type trachea bracket according to claim 1, it is characterised in that：The outer layer (1),
The back warp stitch weave structure that itself stitch weave between middle layer (2) and internal layer (3) connects under being.
3. a kind of used in tissue engineering biomimetic type trachea bracket according to claim 1, it is characterised in that：On the trachea bracket
It is axially distributed that there are two circumferential passageways (4).
4. a kind of used in tissue engineering biomimetic type trachea bracket according to claim 1, it is characterised in that：The outer layer (1)
It is weaved using monofilament with internal layer (3), the middle layer (2) is weaved using multifilament.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810532057.4A CN108754741A (en) | 2018-05-29 | 2018-05-29 | Used in tissue engineering biomimetic type trachea bracket |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810532057.4A CN108754741A (en) | 2018-05-29 | 2018-05-29 | Used in tissue engineering biomimetic type trachea bracket |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108754741A true CN108754741A (en) | 2018-11-06 |
Family
ID=64003594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810532057.4A Pending CN108754741A (en) | 2018-05-29 | 2018-05-29 | Used in tissue engineering biomimetic type trachea bracket |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108754741A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111925227A (en) * | 2020-01-19 | 2020-11-13 | 湖南碳康生物科技有限公司 | Carbon fiber composite material artificial trachea stent and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0461863A (en) * | 1990-06-29 | 1992-02-27 | Nissho Corp | Suture material for medical use |
| CN101972175A (en) * | 2010-11-04 | 2011-02-16 | 东华大学 | Woven artificial trachea and preparation method thereof |
| CN102011238A (en) * | 2010-11-11 | 2011-04-13 | 东华大学 | Machine woven artificial trachea |
| EP2860292A2 (en) * | 2003-05-08 | 2015-04-15 | Tepha, Inc. | Polyhydroxyalkanoate medical textiles and fibers |
-
2018
- 2018-05-29 CN CN201810532057.4A patent/CN108754741A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0461863A (en) * | 1990-06-29 | 1992-02-27 | Nissho Corp | Suture material for medical use |
| EP2860292A2 (en) * | 2003-05-08 | 2015-04-15 | Tepha, Inc. | Polyhydroxyalkanoate medical textiles and fibers |
| CN101972175A (en) * | 2010-11-04 | 2011-02-16 | 东华大学 | Woven artificial trachea and preparation method thereof |
| CN102011238A (en) * | 2010-11-11 | 2011-04-13 | 东华大学 | Machine woven artificial trachea |
Non-Patent Citations (1)
| Title |
|---|
| WANG LIPING等: ""Preparation and Research of a Bionic Woven Tracheal Stent with Horizontal Pipeline"", 《JOURNAL OF DONGHUA UNIVERSITY》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111925227A (en) * | 2020-01-19 | 2020-11-13 | 湖南碳康生物科技有限公司 | Carbon fiber composite material artificial trachea stent and preparation method thereof |
| CN111925227B (en) * | 2020-01-19 | 2022-04-08 | 湖南碳康生物科技有限公司 | Carbon fiber composite material artificial trachea stent and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101972175B (en) | Preparation method of woven artificial trachea | |
| CN101069757B (en) | Two-lay machine-knitted structure textile type artificial blood vessel | |
| CN108754741A (en) | Used in tissue engineering biomimetic type trachea bracket | |
| CN108434530A (en) | A kind of high intensity gradient distribution hypersorption artificial ligament and preparation method thereof | |
| CN206495012U (en) | A kind of woven flexible fabric of jet double-beam loom | |
| CN101069756B (en) | Two-layer warp-knitted tissue textile-type artificial blood vessel | |
| CN214361968U (en) | High-efficient moisture absorption ventilative knitted printed fabric | |
| CN211734621U (en) | Blended elastic jean fabric | |
| CN213013257U (en) | High-count high-density double-layer fabric | |
| CN218749746U (en) | Breathable polyester fabric | |
| CN219007251U (en) | Cool and breathable polyester taffeta lining fabric | |
| CN202279897U (en) | Moisture-absorption sweat-discharge bifacial roughing towel | |
| CN212728808U (en) | Wear-resisting deodorization carbon fiber composite socks | |
| CN219360533U (en) | Crease-resistant polyester taffeta fabric | |
| CN205171077U (en) | Take jacquard weave cloth of square decorative pattern | |
| CN212708347U (en) | Super-soft double-layer modal fabric | |
| CN217993752U (en) | Sweat-absorbent comfortable shirt fabric | |
| CN216804784U (en) | Silk fabric with good elastic effect | |
| CN210234262U (en) | Viscose modal satin fabric | |
| CN217574371U (en) | Four-side elastic composite woven fabric | |
| CN211000294U (en) | Multifunctional high-elastic composite fabric | |
| CN216141691U (en) | Novel three-layer fabric containing silky soft spun yarns | |
| CN215152554U (en) | Multifunctional graphene/polyester composite woven fabric | |
| CN216968930U (en) | High-elastic nylon sticky grey cloth | |
| CN209602714U (en) | The woven flashing fabric of double-beam loom |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20181106 |