CN108717822B - Biological optical imitation equipment - Google Patents
Biological optical imitation equipment Download PDFInfo
- Publication number
- CN108717822B CN108717822B CN201810871008.3A CN201810871008A CN108717822B CN 108717822 B CN108717822 B CN 108717822B CN 201810871008 A CN201810871008 A CN 201810871008A CN 108717822 B CN108717822 B CN 108717822B
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- liquid storage
- storage bottle
- optical
- peristaltic pump
- bio
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- 230000003287 optical effect Effects 0.000 title claims abstract description 60
- 239000007788 liquid Substances 0.000 claims abstract description 65
- 238000003860 storage Methods 0.000 claims abstract description 53
- 230000002572 peristaltic effect Effects 0.000 claims abstract description 46
- 230000004087 circulation Effects 0.000 claims abstract description 36
- 239000008280 blood Substances 0.000 claims abstract description 13
- 210000004369 blood Anatomy 0.000 claims abstract description 13
- 238000013041 optical simulation Methods 0.000 claims description 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 4
- 238000004140 cleaning Methods 0.000 claims description 4
- 238000010146 3D printing Methods 0.000 claims 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract description 10
- 229910052760 oxygen Inorganic materials 0.000 abstract description 10
- 239000001301 oxygen Substances 0.000 abstract description 10
- 230000017531 blood circulation Effects 0.000 abstract description 9
- 230000000694 effects Effects 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000011664 nicotinic acid Substances 0.000 description 2
- 238000004088 simulation Methods 0.000 description 2
- 230000003670 easy-to-clean Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
- G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
- G09B23/28—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
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- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Mathematical Analysis (AREA)
- Mathematical Physics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Algebra (AREA)
- Computational Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Mathematical Optimization (AREA)
- Medical Informatics (AREA)
- Pure & Applied Mathematics (AREA)
- Business, Economics & Management (AREA)
- Educational Administration (AREA)
- Educational Technology (AREA)
- Theoretical Computer Science (AREA)
- External Artificial Organs (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
Abstract
The invention discloses a biological optical imitation device, which comprises a shell, a biological optical imitation, a peristaltic pump and a liquid storage bottle; the biological optical imitation body is arranged in the sample cell of the shell; the peristaltic pump is arranged in the shell; the liquid storage bottle is arranged in the shell; the liquid storage bottle, the biological optical imitation body and the peristaltic pump are sequentially communicated through pipelines to form a circulation loop, and the peristaltic pump is used for driving liquid in the liquid storage bottle to circularly flow in the circulation loop. The optical imitation device is provided with a shell, the biological optical imitation body, the peristaltic pump and the liquid storage bottle are respectively arranged on the shell and are mutually communicated to form a circulation loop, so that the optical, mechanical and blood oxygen blood flow characteristics of biological tissues can be simulated, and the optical imitation body is convenient for a user to carry.
Description
Technical Field
The invention relates to the technical field of medical equipment, in particular to biological optical imitation equipment.
Background
The biological optical imitation device can be used for simulating the optical, mechanical and blood oxygen flow characteristics of biological tissues and can quantitatively calibrate related medical instruments. The biological optical imitation has the following characteristics: 1. has certain optical characteristics and stable properties; 2. having a pourable channel; 3. can be used to simulate part or all of the optical mechanical and blood oxygen flow characteristics of biological tissues.
The biological optical imitation body needs to be matched with peristaltic pumps and other instruments to simulate the optical, mechanical and blood oxygen blood flow characteristics, but the instruments are mutually separated, so that the portability is poor.
In summary, how to provide a portable bio-optical simulation device for simulating optical, mechanical and blood oxygen flow characteristics is a problem to be solved by those skilled in the art.
Disclosure of Invention
In view of the above, the present invention provides a bio-optical imitation device, which integrates an optical imitation body, a liquid storage tank and a peristaltic pump, and can simulate optical, mechanical and blood oxygen blood flow characteristics, and is convenient to carry.
In order to achieve the above purpose, the present invention provides the following technical solutions:
a bio-optical imitation device comprising:
A housing;
a bio-optical imitation disposed within a sample cell of the housing;
A peristaltic pump disposed within the housing;
A reservoir disposed within the housing;
The liquid storage bottle, the biological optical imitation body and the peristaltic pump are sequentially communicated through pipelines to form a circulation loop, and the peristaltic pump is used for driving liquid in the liquid storage bottle to circularly flow in the circulation loop.
Preferably, the bio-optical imitation device further comprises a pulse damper, wherein the pulse damper is fixed on the shell and is connected to the circulation loop.
Preferably, in the above bio-optical simulation apparatus, the pulse damper is disposed between the bio-optical simulation and the peristaltic pump.
Preferably, the bio-optical imitation device further comprises a software development board, wherein the software development board is used for controlling the peristaltic pump, and is provided with a USB port used for being connected with an external computer.
Preferably, the bio-optical imitation device further comprises a speed adjusting knob and a positive and negative adjusting knob which are respectively connected with the software development board; the speed adjusting knob is used for adjusting the rotating speed of the motor of the peristaltic pump, and the positive and negative adjusting knob is used for adjusting the flowing direction of liquid in the circulation loop.
Preferably, in the bio-optical imitation device, a one-key start key connected with the software development board is arranged on the shell.
Preferably, in the above bio-optical imitation device, the liquid storage bottle includes a first liquid storage bottle and a second liquid storage bottle, wherein the first liquid storage bottle stores a solution imitating blood characteristics, and the second liquid storage bottle is used for storing alcohol for cleaning the circulation loop; the first liquid storage bottle and the second liquid storage bottle are used for being connected into the circulation loop respectively.
Preferably, in the above bio-optical imitation device, the bio-optical imitation is a three-dimensionally printed bio-optical imitation.
The invention provides a biological optical imitation device, which comprises a shell, a biological optical imitation, a peristaltic pump and a liquid storage bottle; the biological optical imitation body is arranged in the sample cell of the shell; the peristaltic pump is arranged in the shell; the liquid storage bottle is arranged in the shell; the liquid storage bottle, the biological optical imitation body and the peristaltic pump are sequentially communicated through pipelines to form a circulation loop, and the peristaltic pump is used for driving liquid in the liquid storage bottle to circularly flow in the circulation loop.
The optical imitation device is provided with the shell, the biological optical imitation body, the peristaltic pump and the liquid storage bottle are respectively arranged on the shell and are mutually communicated to form a circulation loop, so that the optical, mechanical and blood oxygen blood flow characteristics of biological tissues can be simulated, and the optical imitation body is convenient for a user to carry.
In addition, the biological optical imitation device has complete functions and can be better used for calibrating optical medical instruments.
Drawings
In order to more clearly illustrate the embodiments of the invention or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, it being obvious that the drawings in the following description are only some embodiments of the invention, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic diagram of a bio-optical simulation device according to an embodiment of the present invention;
FIG. 2 is a schematic diagram of a structure of a bio-optical imitation provided by an embodiment of the present invention;
FIG. 3 is a flowchart illustrating the whole process from the manufacture of a bio-optical imitation to the acquisition of an optical image according to an embodiment of the present invention;
Wherein, in fig. 1-2:
A biological optical imitation 1; a cover plate 2; a housing 3; a USB port 4; a software development board 5; a first reservoir 6; a second reservoir 7; peristaltic pump cabinet 8; a peristaltic pump 9; a forward and reverse rotation adjusting knob 10; a speed adjusting knob 11; a one-key start key 12; a pulse damper 13; a sample cell 14.
Detailed Description
The embodiment of the invention discloses biological optical imitation equipment which integrates an optical imitation, a liquid storage tank and a peristaltic pump, and can simulate optical, mechanical and blood oxygen blood flow characteristics and is convenient to carry.
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Referring to fig. 1-3, an embodiment of the present invention provides a bio-optical simulation device, which includes a housing, a bio-optical simulation 1, a peristaltic pump 9 and a liquid storage bottle; the biological optical imitation 1 is arranged in a sample cell 14 of the shell; peristaltic pump 9 is disposed within the housing; the liquid storage bottle is arranged in the shell; the liquid storage bottle, the biological optical imitation 1 and the peristaltic pump 9 are sequentially communicated through pipelines to form a circulation loop, and the peristaltic pump 9 is used for driving liquid in the liquid storage bottle to circularly flow in the circulation loop.
The optical imitation device is provided with a shell, the biological optical imitation body 1, the peristaltic pump 9 and the liquid storage bottle are respectively arranged on the shell and are mutually communicated to form a circulation loop, so that the optical, mechanical and blood oxygen blood flow characteristics of biological tissues can be simulated, and the optical imitation body is convenient for a user to carry.
In addition, the biological optical imitation device has complete functions and can be better used for calibrating optical medical instruments.
In addition, the biological optical imitation device can simulate biological tissue dynamic parameters such as pulse and the like through a control mechanism besides the optical, mechanical and blood oxygen blood flow characteristics of the biological tissue.
The bio-optical imitation body 1 can be arranged to comprise a plurality of different bio-optical imitation bodies 1 prepared according to the use requirement, and the bio-optical imitation body 1 can be arranged in the sample cell 14 and communicated with a pipeline to form a circulation loop when in use. The bio-optical imitation body 1 can be configured as a three-dimensional printed bio-optical imitation body 1, and can also be configured as other bio-optical imitation bodies 1 manufactured in a traditional way such as pouring. In the actual simulation, from the manufacture of the biological optical imitation 1 to the acquisition of optical images, a perfect system exists, and the flow chart of the whole system is shown in fig. 3.
Specifically, the bio-optical imitation device further comprises a pulse damper 13, wherein the pulse damper 13 is fixed on the shell and is connected to the circulation loop.
Because the peristaltic pump 9 drives the liquid to circulate and flow, the liquid flow can generate obvious fluctuation, and obvious interference effect is generated on the quantitative measurement of the blood flow velocity, the biological optical imitation device provided by the embodiment is provided with the pulse damper 13, and the effect of reducing the fluctuation of the fluid can be achieved. Specifically, a pulse dampener 13 is disposed between the bio-optical proxy 1 and the peristaltic pump 9.
The biological optical imitation device further comprises a software development board 5, wherein the software development board 5 is arranged in the shell and used for controlling the peristaltic pump 9, and the software development board 5 is provided with a USB port 4 communicated with an external computer. When in application, the external computer is utilized to pre-write programs, and the programs are written into the software development board 5 through the USB port 4. The software development board 5 may be configured as a single-chip microcomputer.
Furthermore, the bio-optical imitation device further comprises a speed adjusting knob 11 and a forward and reverse rotation adjusting knob 10 which are respectively connected with the software development board 5, wherein the speed adjusting knob 11 and the forward and reverse rotation adjusting knob 10 can be respectively arranged on the shell, or the two knobs and the peristaltic pump 9 are combined and installed to form a peristaltic pump cabinet 8, and correspondingly, an opening for exposing the two knobs is required to be arranged on the shell; the speed adjusting knob 11 is used for adjusting the motor rotation speed of the peristaltic pump 9, and the counter-rotating adjusting knob 10 is used for adjusting the flow direction of liquid in the circulation loop.
When the device is applied, the speed adjusting buttons are adjusted to different gears, so that the software development board 5 can be driven to send different speed control signals to the motor of the peristaltic pump 9, so that the motor can achieve different rotation speeds, the flowing speed of liquid in the circulation loop is adjusted, and the aim of quantitatively simulating the blood flow characteristics of biological tissues is fulfilled; the forward and reverse rotation adjusting knob 10 is adjusted to different gears, and the software development board 5 can be driven to send different rotation direction control signals to the motor of the peristaltic pump 9, so that the motor can reach different rotation directions, and the flow direction of liquid in the circulation loop can be adjusted.
Furthermore, in the bio-optical imitation device provided in the above embodiment, the shell is provided with a one-key start button 12 connected with the software development board 5, and the one-key start button 12 is a start button of a variable waveform formed by introducing an external computer into the software development board 5.
Preferably, in the above-mentioned bio-optical imitation body device, the liquid storage bottle includes a first liquid storage bottle 6 and a second liquid storage bottle 7, wherein the first liquid storage bottle 6 stores a solution imitating blood characteristics, and the second liquid storage bottle 7 stores alcohol for cleaning the circulation loop; the first liquid storage bottle and the second liquid storage bottle are used for being connected into the circulation loop respectively, namely, only one of the first liquid storage bottle and the second liquid storage bottle 7 is connected into the circulation loop according to different working conditions of the biological optical imitation device.
When simulating the characteristics of biological tissues, the first liquid storage bottle 6 is connected into a circulation loop, namely the first liquid storage bottle 6, the biological optical bionic body 1 and the peristaltic pump 9 are communicated to form the circulation loop, and the peristaltic pump 9 drives the solution in the first liquid storage bottle 6 to circularly flow in the circulation loop; after the simulation is finished, the second liquid storage bottle 7 is connected into a circulation loop, namely the second liquid storage bottle 7, the biological optical bionic body 1 and the peristaltic pump 9 are communicated to form the circulation loop, and the peristaltic body drives alcohol in the second liquid storage bottle 7 to circularly flow in the circulation loop, so that the effect of cleaning the circulation reflux is achieved.
In the biological optical imitation device, the shell comprises a shell body 3 and a cover plate 2, the sample cell 14 is arranged above the cover plate 2, and the peristaltic pump 9, the liquid storage bottle and the software development plate 5 are arranged in the shell body 3; the shell 3 is provided with an opening which is convenient for taking and placing the liquid storage bottle; the pulse damper 13 is fixed on the cover plate 2 and is located outside the space enclosed by the housing 3 and the cover plate 2.
In the bio-optical imitation device provided by the embodiment, the software development board 5, the peristaltic pump 9 and the liquid storage bottle are integrated in the shell, so that the components can be better protected.
All parts in the biological optical imitation apparatus provided by the embodiment are connected through pipelines, and the biological optical imitation apparatus has the characteristics of being detachable, assembled and easy to clean, and all parts can be replaced respectively without affecting the work of all independent parts.
In the present specification, each embodiment is described in a progressive manner, and each embodiment is mainly described in a different point from other embodiments, and identical and similar parts between the embodiments are all enough to refer to each other.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (5)
1. A bio-optical imitation device, comprising:
A housing;
A bio-optical imitation disposed within a sample cell of the housing; the biological optical imitation is formed by three-dimensional printing;
A peristaltic pump disposed within the housing;
A reservoir disposed within the housing;
the liquid storage bottle, the biological optical imitation body and the peristaltic pump are sequentially communicated through pipelines to form a circulation loop, and the peristaltic pump is used for driving liquid in the liquid storage bottle to circularly flow in the circulation loop;
The biological optical imitation device further comprises a pulse damper, wherein the pulse damper is fixed on the shell and is connected with the circulation loop;
The liquid storage bottle comprises a first liquid storage bottle and a second liquid storage bottle, wherein the first liquid storage bottle is used for storing a solution imitating blood characteristics, and the second liquid storage bottle is used for storing alcohol for cleaning the circulation loop; the first liquid storage bottle and the second liquid storage bottle are used for being connected into the circulation loop respectively.
2. The bio-optical simulation apparatus according to claim 1 wherein the pulse dampener is disposed between the bio-optical simulation and the peristaltic pump.
3. The bio-optical simulation device according to claim 1, further comprising a software development board for controlling the peristaltic pump, the software development board being provided with a USB port for connection with an external computer.
4. The bio-optical imitation apparatus of claim 3, further comprising a speed adjustment knob and a forward and reverse adjustment knob respectively connected to the software development board; the speed adjusting knob is used for adjusting the rotating speed of the motor of the peristaltic pump, and the positive and negative adjusting knob is used for adjusting the flowing direction of liquid in the circulation loop.
5. The bio-optical imitation device of claim 3, wherein a one-touch actuation key is provided on the housing and coupled to the software development board.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810871008.3A CN108717822B (en) | 2018-08-02 | 2018-08-02 | Biological optical imitation equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810871008.3A CN108717822B (en) | 2018-08-02 | 2018-08-02 | Biological optical imitation equipment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108717822A CN108717822A (en) | 2018-10-30 |
| CN108717822B true CN108717822B (en) | 2024-05-17 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810871008.3A Active CN108717822B (en) | 2018-08-02 | 2018-08-02 | Biological optical imitation equipment |
Country Status (1)
| Country | Link |
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| CN (1) | CN108717822B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114944099B (en) * | 2022-07-21 | 2022-11-08 | 之江实验室 | Evaluation device of dynamic blood flow-blood oxygen monitoring system |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0830192A (en) * | 1994-07-14 | 1996-02-02 | Terumo Corp | Liquid circulator for blood vessel model |
| JP3089329U (en) * | 2002-04-16 | 2002-10-25 | 日本光電工業株式会社 | Biological circulation simulator |
| CN101974423A (en) * | 2010-08-20 | 2011-02-16 | 北京航空航天大学 | Novel quasi-physiological pulsating flow environment arterial blood vessel tissue engineering reactor |
| CN101976528A (en) * | 2010-09-09 | 2011-02-16 | 华南理工大学 | Biomechanical experiment simulation device for implantation of intravascular stent |
| CN103886796A (en) * | 2014-03-13 | 2014-06-25 | 西安交通大学 | Organ perfusion system for surgery simulation trainers |
| CN104946528A (en) * | 2015-07-16 | 2015-09-30 | 中南大学湘雅医院 | Primary hepatic tissue cell separation system and method |
| CN105255723A (en) * | 2015-09-30 | 2016-01-20 | 重庆大学 | Using method for blood vessel fluid bionic cell experiment instrument |
| CN106234351A (en) * | 2016-07-29 | 2016-12-21 | 浙江大学宁波理工学院 | Fluidization for biological tissue loads or takes out the device of cryoprotective agent |
| CN206489810U (en) * | 2016-08-31 | 2017-09-12 | 有研医疗器械（北京）有限公司 | The in-vitro simulated and performance test experimental apparatus of sustainer PCI |
| CN208954462U (en) * | 2018-08-02 | 2019-06-07 | 中国科学技术大学 | A kind of imitative body equipment of Photobiology |
-
2018
- 2018-08-02 CN CN201810871008.3A patent/CN108717822B/en active Active
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0830192A (en) * | 1994-07-14 | 1996-02-02 | Terumo Corp | Liquid circulator for blood vessel model |
| JP3089329U (en) * | 2002-04-16 | 2002-10-25 | 日本光電工業株式会社 | Biological circulation simulator |
| CN101974423A (en) * | 2010-08-20 | 2011-02-16 | 北京航空航天大学 | Novel quasi-physiological pulsating flow environment arterial blood vessel tissue engineering reactor |
| CN101976528A (en) * | 2010-09-09 | 2011-02-16 | 华南理工大学 | Biomechanical experiment simulation device for implantation of intravascular stent |
| CN103886796A (en) * | 2014-03-13 | 2014-06-25 | 西安交通大学 | Organ perfusion system for surgery simulation trainers |
| CN104946528A (en) * | 2015-07-16 | 2015-09-30 | 中南大学湘雅医院 | Primary hepatic tissue cell separation system and method |
| CN105255723A (en) * | 2015-09-30 | 2016-01-20 | 重庆大学 | Using method for blood vessel fluid bionic cell experiment instrument |
| CN106234351A (en) * | 2016-07-29 | 2016-12-21 | 浙江大学宁波理工学院 | Fluidization for biological tissue loads or takes out the device of cryoprotective agent |
| CN206489810U (en) * | 2016-08-31 | 2017-09-12 | 有研医疗器械（北京）有限公司 | The in-vitro simulated and performance test experimental apparatus of sustainer PCI |
| CN208954462U (en) * | 2018-08-02 | 2019-06-07 | 中国科学技术大学 | A kind of imitative body equipment of Photobiology |
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| CN108717822A (en) | 2018-10-30 |
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