CN108704112A - A kind of dizziness mixture and preparation method thereof - Google Patents

A kind of dizziness mixture and preparation method thereof Download PDF

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Publication number
CN108704112A
CN108704112A CN201810634787.5A CN201810634787A CN108704112A CN 108704112 A CN108704112 A CN 108704112A CN 201810634787 A CN201810634787 A CN 201810634787A CN 108704112 A CN108704112 A CN 108704112A
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dizziness
mixture
rhizoma
dizzy
filtration
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古联
刘永辉
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First Affiliated Hospital of Guangxi Medical University
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First Affiliated Hospital of Guangxi Medical University
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    • A61K36/88—Liliopsida (monocotyledons)
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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Abstract

The invention discloses a kind of dizziness mixture and preparation method thereof, include the raw material of following parts by weight：Rhizoma pinellinae praeparata 10, Rhizoma Atractylodis Macrocephalae 20, rhizoma alismatis 15, fructus viticis 10, cassia twig 10, arisaema cum bile 10, Rhizoma Gastrodiae 20, Poria cocos 20, ginger 10 and honey-fried licorice root 10；The beneficial effects of the invention are as follows：The present invention is to choose each bulk pharmaceutical chemicals and its proportioning under Traditional Chinese medical theory and clinical experience guidance, utilize its mutual collaboration or resistant function, curative effect is improved, there is invigorating the spleen, resolving sputum, clearing damp, relieve dizziness, high fever, infantile convulsions, epilepsy, etc., is only dizzy, cure mainly various dizziness, symptoms include it is dizzy, dizzy, clear key is unfavorable, or with nausea and vomiting, palpitaition, the malaise symptoms such as chest gastral cavity ruffian, the present invention have significant in efficacy, the advantages for the treatment of both manifestation and root cause of disease, Small side effects.

Description

A kind of dizziness mixture and preparation method thereof
Technical field
The present invention relates to a kind of tcm field, specifically a kind of dizziness mixture and preparation method thereof.
Background technology
Dizziness is a kind of dynamic property generated because body is to planotopokinesia or positional illusion, it is related to multiple Section.Vast majority of people undergoes this disease in life.According to statistics, vertigo accounts for the 5% of outpatients in internal medicine clinics, accounts for hals,Nasen und Ohrenheilkunde door 15% examined.Dizziness can be divided into true vertigo and nonsystemic vertigo.True vertigo is caused by eye, proprioceptive sensation or vestibular system disease , there are apparent foreign object or itself sense of rotation.Nonsystemic vertigo is mostly caused by whole body system disease, such as angiocardiopathy, brain blood Pipe disease, anaemia, uremia, drug poisoning, endocrine system disease and neurosis etc. nearly all have the giddy disease of weight not etc. Shape, the patient feels " fluttering is swung ", not clearly rotation sense.
The reason of dizziness；Anaemia old man should go to hospital to check that, seeing is if any dizzy, weak, pale complexion performance No anaemia.If the elderly does not pay attention to nutrition and health care, it is easy to suffer from anaemia.In addition, indigestion, peptic ulcer, alimentary canal The gerontal patient of bleeding and chronic inflammatory diseases can secondary anemia；The high hyperlipidemia of blood viscosity, piastrenemia etc. Keep blood viscosity high, slow blood flow causes blood supply insufficiency of brain, occurs to be easy the symptoms such as tired, dizzy, weak.Wherein cause height There are many reason of blood fat, and most importantly usually dietary structure is unreasonable；Arteriosclerotic feels dizziness, and often loses Dormancy, tinnitus, emotional lability, forgetful, four limbs are numb.Cerebral arteriovenous malformation makes vessel diameter become smaller, and cerebral blood flow declines, and generates brain and supplies Blood, for hypoxgia, cause dizziness；Cervical spondylosis often occur neck is felt nervous, flexibility ratio is limited, it is even have that pain, finger is numb, sends out cool, There is sense of heaviness.Cervical vertebra hyperplasia squeezes neck vertebral artery, causes cerebral insufficiency, is the main reason for disease causes dizziness；High blood Press hypertensive patient in addition to dizziness, also often with discomforts such as alliteration, nervous, agitation, tinnitus, insomnias；Heart disease coronary heart disease is early Phase, somebody may feel that headache, dizziness, weakness of limbs, spirit are not easy to collect medium.Mainly because congee occurs for heart coronary artery Sample hardens, and causes blood supply insufficiency and causes dizziness.
Invention content
The purpose of the present invention is to provide dizziness mixture, to solve the problems mentioned in the above background technology.
To achieve the above object, the present invention provides the following technical solutions：
Dizziness mixture includes the raw material of following parts by weight：
Rhizoma pinellinae praeparata 10, Rhizoma Atractylodis Macrocephalae 20, rhizoma alismatis 15, fructus viticis 10, cassia twig 10, arisaema cum bile 10, Rhizoma Gastrodiae 20, Poria cocos 20, ginger 10 and Honey-fried licorice root 10.
The preparation method of dizziness mixture, includes the following steps：
Step 1：Extraction：Rhizoma pinellinae praeparata, Rhizoma Atractylodis Macrocephalae, rhizoma alismatis, fructus viticis, cassia twig, arisaema cum bile, Rhizoma Gastrodiae, Poria cocos, ginger and toast is sweet Grass is cleaned, and in blocks, section or coarse powder are processed；Usually extracting by the decocting method of decoction, inventory is more due to 1 time, therefore Decocting time is every time 1-2h, takes juice to stay slag, then decocted, 3 times repeatedly, merges juice, and filtration is spare；
Step 2：Purification：In order to reduce the precipitation in mixture, purified treatment need to be used, processing is staticized using water extract-alcohol precipitation；
Step 3：Concentration：Extracting solution after filtration is suitably concentrated again.Its concentrating degree, generally with daily measure 30 ~ 60ml is advisable；
Step 4：Packing：Corrigent, the preservative that doses are added before packing, in liquid can be into after stirring evenly Row coarse filtration, refined filtration are fitted into sterile, clean, dry dactylethrae or suitable container, sealing.
Preferably, the corrigent that the step 4 is added has honey, simple syrup, glycyrrhizic acid and stevioside etc..
Preferably, the preservative that the step 4 is added has sorbic acid, benzoic acid and propionic acid etc..
Preferably, mixture 100ml/ bottles obtained in the step 4.
Preferably, the instructions of taking of the mixture：20ml, three times a day.
Preferably, the quality examination of mixture made from the step 4 can be checked by following items：Visual examination（Packet Include clarity test）, the inspection of device difference, health examination, Qualitive test, the measurement of active constituent content, relative density survey Fixed etc., the inspection of these projects can substantially efficiently control the quality of mixture.
Compared with prior art, the beneficial effects of the invention are as follows：Invigorating the spleen resolving sputum, clearing damp, relieves dizziness, high fever, infantile convulsions, epilepsy, etc., is only dizzy.It cures mainly various dizzy Dizzy symptoms include dizzy, dizzy, clear key is unfavorable, or with nausea and vomiting, palpitaition, the discomforts such as chest gastral cavity ruffian.
Specific implementation mode
The technical solution of this patent is described in more detail With reference to embodiment.
Embodiment one
Dizziness mixture includes the raw material of following parts by weight：
Rhizoma pinellinae praeparata 10, Rhizoma Atractylodis Macrocephalae 20, rhizoma alismatis 15, fructus viticis 10, cassia twig 10, arisaema cum bile 10, Rhizoma Gastrodiae 20, Poria cocos 20, ginger 10 and Honey-fried licorice root 10.
Each raw material Chinese medicine in prescription of the present invention has detailed in Chinese Pharmacopoeia, Chinese dictionary and its China's book on Chinese herbal medicine It records.It is raw material that the present invention, which selects one of the most common Chinese medicine, gives full play to the pharmacological effect of each component：
Rhizoma pinellinae praeparata：In spherical or be broken into irregular particle shape.Surface yellowish white, yellow or brown color.Matter is more crisp or It is hard crisp.It cures mainly eliminating dampness and eliminating phlegm.For abundant expectoration cough and asthma, phlegm retention anti-dazzle nervous, anemophlegmatic vertigo, phlegm and headache；
Rhizoma Atractylodis Macrocephalae：Meridian distribution of property and flavor, bitter is sweet, warm-natured.Returns spleen, stomach, major function；Strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, peace Tire.For spleen eating less, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, oedema, spontaneous perspiration, fetal irritability.Rhizoma Atractylodis Macrocephalae invigorating the spleen and stomach, tocolysis.With In spleen eating less, diarrhea loose stool, fetal irritability；
Rhizoma alismatis：Nature and flavor：It is sweet, cold, there is the effect of diuresis, clearing away damp-heat, for treating difficult urination, oedema turgor, diarrhea urine Less, phlegmatic vertigo, puckery pain of heat gonorrhea, hyperlipidemia；
Fructus viticis：Acrid flavour, hardship, cold nature.Return lung, bladder, Liver Channel.Its primary efficacy is dispelling wind and heat from the body, head clearing, at dehumidifying Joint.It is usually used in exogenous headache, polarization intermittent headache, the mesh that swoons is dark, many tear of red eyes, pain, gingivitis, arthritis with fixed pain caused by dampness contraction in mesh eyeball；
Cassia twig：Meridian distribution of property and flavor；Acrid, sweet, warm enter lung, the heart, bladder warp.Effect；Sweating expelling pathogenic factors from muscles and skin, warming meridian, helps yang transforming qi；
Arisaema cum bile；Meridian distribution of property and flavor；Bitter, micro-pungent, cool, clearing heat and eliminating phlegm, dispelling wind and relieving convulsion are used for phlegm-heat cough, cough up phlegm yellow thick, middle wind phlegm Fan, demented frightened epilepsy；
Rhizoma Gastrodiae；Property sweet and neutral, enters Liver Channel；Major function ceases wind, arresting convulsion.Dizziness pupil is controlled, head wind headache, extremity numbness, half body is not Then, aphasia, infantile epilepsy and convulsions.
Poria cocos：It is sweet in flavor, light, it is mild-natured, it cures mainly for oedema oliguria, phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea, the mind is not Peace, insomnia of palpitating with fear.
Ginger：Ginger acrid flavour, slightly warm in nature.Return lung, spleen, stomach.With relieving exterior syndrome and dispelling cold, warming middle energizer to arrest vomiting, warm lung cough-relieving, removing toxic substances The effect of, it is usually used in anemofrigid cold, taste sympotoms caused by cold factors, gastrofrigid vomiting, lung cold cough, solving toxin of fish and crab；
Honey-fried licorice root：Honey-fried licorice root is similar round or oval section, and surface rufous or taupe brown, micro- glossy, section yellow is extremely Buff, cambium ring is apparent, ray irradiation shape.Zhigancao decoction has benefiting qi and nourishing yin, and activate yang multiple arteries and veins therapeutic efficiency.
The preparation method of dizziness mixture, includes the following steps：
Step 1：Extraction：Rhizoma pinellinae praeparata, Rhizoma Atractylodis Macrocephalae, rhizoma alismatis, fructus viticis, cassia twig, arisaema cum bile, Rhizoma Gastrodiae, Poria cocos, ginger and toast is sweet Grass is cleaned, and in blocks, section or coarse powder are processed；Usually extracting by the decocting method of decoction, inventory is more due to 1 time, therefore Decocting time is every time 1-2h, takes juice to stay slag, then decocted, 3 times repeatedly, merges juice, and filtration is spare；
Step 2：Purification：In order to reduce the precipitation in mixture, purified treatment need to be used, processing is staticized using water extract-alcohol precipitation；
Step 3：Concentration：Extracting solution after filtration is suitably concentrated again.Its concentrating degree, generally with daily measure 30 ~ 60ml is advisable；
Mixture can select addition corrigent and preservative as needed.Common corrigent has honey, simple syrup, glycyrrhizic acid and sweet tea Chrysanthemum glycosides etc.；Preservative has sorbic acid, benzoic acid and propionic acid etc..
Step 4：Packing：Corrigent, the preservative that doses are added before packing, in liquid can be into after stirring evenly Row coarse filtration, refined filtration are fitted into sterile, clean, dry dactylethrae or suitable container, sealing.
Preferably, mixture 100ml/ bottles obtained in the step 4
Preferably, the instructions of taking of the mixture：20ml, three times a day
The quality examination of mixture can be checked by following items：Visual examination（Including clarity test）, the inspection of device difference, Health examination, Qualitive test, the measurement of active constituent content, relative density determination etc., the inspection of these projects substantially can Efficiently control the quality of mixture.
Model case：Through clinical conditions patients with vertigo totally 500, the age is 300 of 29 years old or more, age 29 Year old or less（Including 29 years old）200.350 to fully recover in 500 patients, effective 150, total effective rate is up to 100%.Through After treatment, symptom gradually mitigates or fully recovers, and has certain therapeutic effect for its complication.
Embodiment two
Dizziness mixture includes the raw material of following parts by weight：
Rhizoma pinellinae praeparata 11, Rhizoma Atractylodis Macrocephalae 15, rhizoma alismatis 10, fructus viticis 10, cassia twig 10, arisaema cum bile 20, Rhizoma Gastrodiae 12, Poria cocos 20, ginger 10 and Honey-fried licorice root 15.
Embodiment three
Dizziness mixture includes the raw material of following parts by weight：
Rhizoma pinellinae praeparata 14, Rhizoma Atractylodis Macrocephalae 15, rhizoma alismatis 15, fructus viticis 10, cassia twig 10, arisaema cum bile 20, Rhizoma Gastrodiae 20, Poria cocos 20, ginger 10 and Honey-fried licorice root 10.
Example IV
Dizziness mixture includes the raw material of following parts by weight：
Rhizoma pinellinae praeparata 12, Rhizoma Atractylodis Macrocephalae 20, rhizoma alismatis 15, fructus viticis 10, cassia twig 10, arisaema cum bile 10, Rhizoma Gastrodiae 20, Poria cocos 20, ginger 20 and Honey-fried licorice root 15.
Embodiment five
Dizziness mixture includes the raw material of following parts by weight：
Rhizoma pinellinae praeparata 11, Rhizoma Atractylodis Macrocephalae 10, rhizoma alismatis 10, fructus viticis 10, cassia twig 10, arisaema cum bile 15, Rhizoma Gastrodiae 15, Poria cocos 20, ginger 10 and Honey-fried licorice root 10.
Embodiment six
Dizziness mixture includes the raw material of following parts by weight：
Rhizoma pinellinae praeparata 15, Rhizoma Atractylodis Macrocephalae 10, rhizoma alismatis 15, fructus viticis 10, cassia twig 10, arisaema cum bile 15, Rhizoma Gastrodiae 20, Poria cocos 20, ginger 10 and Honey-fried licorice root 12.
Embodiment seven
Dizziness mixture includes the raw material of following parts by weight：
Rhizoma pinellinae praeparata 15, Rhizoma Atractylodis Macrocephalae 15, rhizoma alismatis 15, fructus viticis 20, cassia twig 20, arisaema cum bile 20, Rhizoma Gastrodiae 15, Poria cocos 20, ginger 10 and Honey-fried licorice root 15.
The better embodiment of this patent is explained in detail above, but this patent is not limited to above-mentioned embodiment party Formula, one skilled in the relevant art within the scope of knowledge, can also be under the premise of not departing from this patent objective It makes a variety of changes.

Claims (7)

1. dizziness mixture, which is characterized in that include the raw material of following parts by weight：
Rhizoma pinellinae praeparata 10, Rhizoma Atractylodis Macrocephalae 20, rhizoma alismatis 15, fructus viticis 10, cassia twig 10, arisaema cum bile 10, Rhizoma Gastrodiae 20, Poria cocos 20, ginger 10 and Honey-fried licorice root 10.
2. the preparation method of dizziness mixture, includes the following steps：
Step 1：Extraction：Rhizoma pinellinae praeparata, Rhizoma Atractylodis Macrocephalae, rhizoma alismatis, fructus viticis, cassia twig, arisaema cum bile, Rhizoma Gastrodiae, Poria cocos, ginger and toast is sweet Grass is cleaned, and in blocks, section or coarse powder are processed；Usually extracting by the decocting method of decoction, inventory is more due to 1 time, therefore Decocting time is every time 1-2h, takes juice to stay slag, then decocted, 3 times repeatedly, merges juice, and filtration is spare；
Step 2：Purification：In order to reduce the precipitation in mixture, purified treatment need to be used, processing is staticized using water extract-alcohol precipitation；
Step 3：Concentration：Extracting solution after filtration is suitably concentrated again；Its concentrating degree, generally with daily measure 30 ~ 60ml is advisable；
Step 4：Packing：Corrigent, the preservative that doses are added before packing, in liquid can be into after stirring evenly Row coarse filtration, refined filtration are fitted into sterile, clean, dry dactylethrae or suitable container, sealing.
3. dizziness mixture according to claim 2, which is characterized in that the corrigent that the step 4 is added has honey, list Syrup, glycyrrhizic acid and stevioside etc..
4. dizziness mixture according to claim 2, which is characterized in that the preservative that the step 4 is added have sorbic acid, Benzoic acid and propionic acid etc..
5. dizziness mixture according to claim 2, which is characterized in that mixture 100ml/ bottles obtained in the step 4.
6. dizziness mixture according to claim 5, which is characterized in that the instructions of taking of the mixture：20ml, one day 3 times.
7. dizziness mixture according to claim 2, which is characterized in that the quality examination of mixture can made from the step 4 It is checked by following items：Visual examination（Including clarity test）, the inspection of device difference, health examination, Qualitive test, Measurement, relative density determination of active constituent content etc., the inspection of these projects can substantially efficiently control the matter of mixture Amount.
CN201810634787.5A 2018-06-20 2018-06-20 A kind of dizziness mixture and preparation method thereof Pending CN108704112A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112206268A (en) * 2020-11-16 2021-01-12 河南中医药大学 Traditional Chinese medicine for treating phlegm-turbidity and middle-obstruction type dizziness

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Publication number Priority date Publication date Assignee Title
CN102908604A (en) * 2012-11-11 2013-02-06 李承平 Bighead atractylodes rhizome and gastrodia tuer capsules
EP2937094A4 (en) * 2012-12-21 2016-08-31 Tasly Pharmaceutical Group Co Pharmaceutical composition for treating headache, and preparation method thereof
CN107224566A (en) * 2017-06-21 2017-10-03 潘志诚 A kind of Chinese medicine composition for treating cervical vertigo

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102908604A (en) * 2012-11-11 2013-02-06 李承平 Bighead atractylodes rhizome and gastrodia tuer capsules
EP2937094A4 (en) * 2012-12-21 2016-08-31 Tasly Pharmaceutical Group Co Pharmaceutical composition for treating headache, and preparation method thereof
CN107224566A (en) * 2017-06-21 2017-10-03 潘志诚 A kind of Chinese medicine composition for treating cervical vertigo

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112206268A (en) * 2020-11-16 2021-01-12 河南中医药大学 Traditional Chinese medicine for treating phlegm-turbidity and middle-obstruction type dizziness
CN112206268B (en) * 2020-11-16 2021-12-24 河南中医药大学 Traditional Chinese medicine for treating phlegm-turbidity and middle-obstruction type dizziness

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Application publication date: 20181026