CN108686094A - A kind of Traditional Chinese medicine for decreasing blood sugar and preparation method thereof - Google Patents
A kind of Traditional Chinese medicine for decreasing blood sugar and preparation method thereof Download PDFInfo
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- CN108686094A CN108686094A CN201810814177.3A CN201810814177A CN108686094A CN 108686094 A CN108686094 A CN 108686094A CN 201810814177 A CN201810814177 A CN 201810814177A CN 108686094 A CN108686094 A CN 108686094A
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- A61K36/718—Coptis (goldthread)
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Abstract
The present invention relates to pharmaceutical technology field, a kind of Traditional Chinese medicine for decreasing blood sugar and preparation method thereof is particularly disclosed.The Traditional Chinese medicine for decreasing blood sugar, using Radix Astragali, Radix Angelicae Sinensis, pueraria lobata, Poria cocos, Rhizoma Atractylodis Macrocephalae, root of Aucklandia lappa Decne, wrinkled giant hyssop, Chinese yam, mulberry leaf, purslane, Ramulus euonymi, the coptis, Radix Salviae Miltiorrhizae, radix paeoniae rubra, Rhizoma Chuanxiong, prepared rehmannia root, the tuber of dwarf lilyturf, Schisandra chinensis and Radix Glycyrrhizae as raw material, it is mixed according to certain weight proportion.Raw medicinal material of the present invention is all made of natural Chinese medicine material, and configuration is easy, and medicine source is extensive, of low cost, follows the prescriptions principle of Chinese medicine, and all medicines share brings out the best in each other.
Description
(One)Technical field
The present invention relates to pharmaceutical technology field, more particularly to a kind of Traditional Chinese medicine for decreasing blood sugar and preparation method thereof.
(Two)Background technology
Type 2 Diabetes In China incidence surges in Past 30 Years, has become one of public's major health risk.Lancet
"Lancet Diabetes & Endocrinology"Once on-line continuous delivers three series texts for paying close attention to diabetes mellitus in China to magazine
Chapter claims China to have more than 100,000,000 population at present and suffers from diabetes, and the number is considerably beyond other countries in the world.According to the world
Diabetic combinations meeting (IDF) counts, and existing diabetes mellitus in China patient ranks the first in the world.China has 1,300,000 people to die of sugar within 2015
Rejuvenation trend is gradually presented wherein 40.8% man-year age is less than 60 years old in urine disease and its complication.IDF predicts the year two thousand forty,
The whole world will have 6.42 hundred million people and suffer from diabetes, and diabetes mellitus in China patient is up to 1.51 hundred million.
It is endangered in face of so huge patient population and caused by diabetes and its complication, doctors attempt various control
Conditions of patients and pain are treated and slowed down to treatment method.Traditional Chinese medicine is earliest one of the medicine for the treatment of diabetes on the books, is browsed
Ancient books can be divided into scopes such as " quenching one's thirst " " the spleen-warm syndromes " according to its clinical symptoms.Early in"The Yellow Emperor's Canon of Internal Medicine"Epoch just refer to.When
To today, by procreation, baptism and continuous practice summary over the past thousands of years, Chinese medicine has had accumulated abundant clinical experience, after
Continue and escorts for human health.
Diabetes China medicine is known as " diabete ".Diabete lesion internal organs mainly in lung, spleen, kidney, three it is dirty interact,
Mainly with the deficiency of vital energy for this, blood stasis is mark."The big opinion of Plain Questions YIN YANG classification of natural phenomena"Speech:" treatment of disease must aim at its pathogenesis ", it is whole to search for the primary cause of disease in treatment
Embodiment of the idea with diagnosis and treatment in treatment is seen, is the dominant ideas of traditional Chinese medicine treatment.Qi deficiency to blood stasis is the main of diabetes
The interpretation of the cause, onset and process of an illness, therefore treatment should take into account " deficiency of vital energy " and " blood stasis "." QI invigorating ", first gas it is prosperous can green blood, second gas row then blood, to effect a permanent cure it
Method;" promoting blood circulation " then the stasis of blood must be logical except blood vessels, and new blood must be raw, for the method taken stopgap measures.Tonifying Qi not stagnation resolvation, then hemostasis do not go, biochemical weary source, effect
Not persistently;QI invigorating, then deficiency of vital energy inability promoting circulation of blood, old stasis of blood difficulty are not gone for stagnation resolvation, new blood difficulty life.Clear Wang Qingren"The correction of the errors of medical works":" gas is logical
Without stagnant, blood is lived without the stasis of blood, and gas, which leads to blood, lives, what, which is suffered from the disease, does not remove."
It can thus be appreciated that treatment diabetes QI invigorating is simultaneously, it is necessary to synchronous progress promoting blood circulation and removing blood stasis, can prove effective.
(Three)Invention content
In order to compensate for the shortcomings of the prior art, the present invention provides a kind of simple for process, of low cost, effective hypoglycemic
Chinese medicine and preparation method thereof.
The present invention is achieved through the following technical solutions:
A kind of Traditional Chinese medicine for decreasing blood sugar is mixed by the raw material of following parts by weight:30-50 parts of Radix Astragali, 15-25 parts of Radix Angelicae Sinensis, Pueraria lobota
15-25 parts of root, 15-25 parts of Poria cocos, 15-25 parts of Rhizoma Atractylodis Macrocephalae, 6-15 parts of root of Aucklandia lappa Decne, 15-25 parts of wrinkled giant hyssop, 15-25 parts of Chinese yam, mulberry leaf 20-
40 parts, 15-25 parts of purslane, 15-25 parts of Ramulus euonymi, 8-12 parts of the coptis, 15-25 parts of Radix Salviae Miltiorrhizae, 15-25 parts of radix paeoniae rubra, Rhizoma Chuanxiong 15-25
Part, 15-25 parts of prepared rehmannia root, 15-25 parts of the tuber of dwarf lilyturf, 6-15 parts of Schisandra chinensis, 8-12 parts of Radix Glycyrrhizae.
Its preferred weight proportion is:
30-50 parts of Radix Astragali, 15-25 parts of Radix Angelicae Sinensis, 15-25 parts of pueraria lobata, 15-25 parts of Poria cocos, 15-25 parts of Rhizoma Atractylodis Macrocephalae, 6-15 parts of root of Aucklandia lappa Decne, the leaves of pulse plants
15-25 parts fragrant, 15-25 parts of Chinese yam, 20-40 parts of mulberry leaf, 15-25 parts of purslane, 15-25 parts of Ramulus euonymi, 8-12 parts of the coptis, Radix Salviae Miltiorrhizae
15-25 parts, 15-25 parts of radix paeoniae rubra, 15-25 parts of Rhizoma Chuanxiong, 15-25 parts of prepared rehmannia root, 15-25 parts of the tuber of dwarf lilyturf, 6-15 parts of Schisandra chinensis, Radix Glycyrrhizae
8-12 parts.
Chinese medicine of the present invention is capsule.The mode of taking be it is oral, three times per day, before meals half an hour take, every time
0.5g, two weeks as a treatment course.
The present invention combines dialectical demonstration by the research to traditional Chinese medicine, and the multi-party length for collecting many families seeks most preferably to control
Treatment scheme, using natural Chinese traditional medicines raw material, is matched through system research, scientific compatibility using astragalus, angelica by theory of traditional Chinese medical science prescription
The pueraria lobata that 5 invigorating the spleen promote the production of body fluid to quench thirst clears liver and moisturizes the mulberry leaf only quenched one's thirst to treat qi deficiency to blood stasis patients with type Ⅰ DM, significant effect;It ties again
The Traditional Chinese medicine for decreasing blood sugar that Traditional Chinese Medicine technology is configured to the present invention meticulously is closed, there is preferable effect to diabetes.
The preparation method of above-mentioned Traditional Chinese medicine for decreasing blood sugar, includes the following steps:
(1)Each bulk pharmaceutical chemicals are weighed respectively, it is spare;
(2)It takes Radix Codonopsis, Schisandra chinensis, pueraria lobata, root of Aucklandia lappa Decne, wrinkled giant hyssop, Chinese yam, purslane, Radix Salviae Miltiorrhizae, radix paeoniae rubra, prepared rehmannia root to be uniformly mixed, adds water
It decocts twice, merges filtrate twice after filtrate is collected by filtration, be condensed into medicinal extract after cooling, then powder is ground into after drying, must answer
Close object A;
(3)Radix Astragali, Radix Angelicae Sinensis, Radix Ophiopogonis, mulberry leaf, Poria cocos, Rhizoma Atractylodis Macrocephalae, Ramulus euonymi, the coptis, Rhizoma Chuanxiong, Radix Glycyrrhizae are taken, ethyl alcohol is added to impregnate, is extracted
Twice, merge extracting solution, filter, be condensed into medicinal extract, crushed after being dried obtains compound B;
(4)Compound A and compound B are uniformly mixed, capsule product is made in sterilization.
The present invention more excellent technical solution be:
Step(2)In, in decocting twice, for the first time plus the water of 3 times of weight boils by intense fire, is then cooked by slow fire 1 hour, filtering is received
Collect filtrate and filter residue;Water is added into filter residue, is regarded no filter slag as criterion, is boiled by intense fire, is then cooked by slow fire 30 minutes, and filtering is received
Collect filtrate.
The medicinal extract that density is 1.1-1.2g/mL is condensed into after filtrate cooling to be ground into powder after drying at 80 DEG C, must answer
Close object A.
Step(3)In, add the ethyl alcohol of mass concentration 70% to impregnate 0.5-1.5 hours, extraction is twice, 1-2 hours each, closes
And extracting solution.
The relative density of medicinal extract is 1.2.
In drug of the present invention, monarch drug in a prescription is Radix Astragali, Radix Angelicae Sinensis, pueraria lobata, mulberry leaf.The sweet Wen Shengfa of Radix Astragali, work(arrogate to oneself tonifying Qi, are " tonic
Length ".This product energy help three is burnt, all gas of internal organs in table.The characteristics of Radix Astragali, is that gas is thin, light and be apt to walk, so in addition to help,
Also have the work(for accumulateing passage concurrently.So"Mingyi Bielu"In point out " by extravesated blood between the five internal organs ".Radix Angelicae Sinensis acrid flavour, hardship, sweet, tepor, have
The effect of replenishing and activating blood, menstruction regulating and pain relieving.There are much the discussion of Radix Angelicae Sinensis in successive dynasties' successive dynasties, such as"Haigoushen"In mention Radix Angelicae Sinensis tool
There is the power of " broken place blood ".Pueraria lobata taste is dry, pungent, cool in nature, attaches to the lung and stomach meridians, first recorded in"Sheng Nong's herbal classic", there is expelling pathogenic factors from muscles and skin to bring down a fever, give birth to
The effect of Tianjin quenches the thirst, Shengyang Zhixie, is a kind of relatively broad Chinese medicine of clinical application.Zooscopy finds that Puerarin can be effective
It improves diabetic mice insulin sensitivity, inhibit insulin resistance, have for reducing blood glucose level and improving sugar tolerance
Important function has positive effect in treating diabetes.Mulberry leaf are the dried leaf of moraceae plants mulberry Morus alba L., are begun
It is loaded in"Sheng Nong's herbal classic", Chinese medicine is also known as " Radix Rhodiolae " " myriosorus maidenhair herb ".It is its bitter, sweet, it is cold in nature, there is dispelling wind and heat from the body, clearing lung-heat profit
It is dry, the effect of clearing liver and improving vision, it can be used for anemopyretic cold, lung-heat type cough, dizziness headache, hot eyes is dim-sighted."Compendium of Materia Medica"It records:
" mulberry leaf are the medicine of brothers Yang Ming, and juice decocts Dai Ming, can only be quenched one's thirst, improving eyesight long hair ".Modern research shows that mulberry leaf have hypoglycemic, drop
The pharmacological actions such as blood pressure, reducing blood lipid, anti-aging.In recent years, the hypoglycemic effect of mulberry leaf is concerned, and prevents the work(of diabetes
Effect is widely recognized.
In addition, early period shows Radix Astragali to the diabetes rat experimental result of astragalus, angelica main component Astragaloside IV ferulic acid
First glycosides ferulic acid group blood glucose declines more apparent.Clinical application astragalus, angelica, the pueraria lobata that compatibility invigorating the spleen promotes the production of body fluid to quench thirst, clearing liver are moisturized
The mulberry leaf only quenched one's thirst treat qi deficiency to blood stasis patients with type Ⅰ DM, significant effect.
Poria cocos, Rhizoma Atractylodis Macrocephalae, root of Aucklandia lappa Decne, wrinkled giant hyssop, Chinese yam are ministerial drug, play the work(of strengthening the spleen and replenishing qi altogether.Assistant is with coptis invigorating the spleen to dry, clearing stomach
Fire, because blood stasis runs through diabetes always, Gu Zuo is promoting blood circulation and removing blood stasis with Radix Salviae Miltiorrhizae, radix paeoniae rubra, Rhizoma Chuanxiong.Purslane, Ramulus euonymi, prepared rehmannia root,
The tuber of dwarf lilyturf, Schisandra chinensis, Radix Glycyrrhizae are to make medicine altogether.
The Chinese medicine of the present invention can be used conventional method and every medicinal material in prescription carried out compatibility in proportion, by existing preparation
The various clinical applicable dosage forms of manufacturing process, ingredients used is commercially available by examining qualified Chinese medicine.
Raw medicinal material of the present invention is all made of natural Chinese medicine material, and configuration is easy, and medicine source is extensive, of low cost, abides by
The prescriptions principle of Chinese medicine is followed, all medicines share brings out the best in each other, and preparation dose is small, and effective ingredient is easy to discharge, and inhales
Receive fast, bioavilability is high, so that drug effect is fully volatilized, verifies by clinic application, significant in efficacy reliable, mild in medicine property and,
Do not occur toxic side effect, has a extensive future.
Avoided pungent and cold food during medication, and emotional stimulation, life is avoided to want regular.
The beneficial effects of the present invention are:
(1)Medicament is made of pure Chinese medicine, and the compound CP method relevant regulations of each component are free of using the compatibility effect of each taste Chinese medicine
Chemical components are free of hormone, have no toxic side effect, treating both manifestation and root cause of disease, have the function that preferably hypoglycemic;
(2)Short treating period, total effective rate is high, difficulty in relapse after healing;
(3)It is simple for process, production cost is reduced, the financial burden of patient is alleviated.
(Four)Specific implementation mode
Carry out the explained in details present invention below by specific embodiment, but is not intended as the limitation to the content of present invention.
Embodiment 1:
A kind of Traditional Chinese medicine for decreasing blood sugar compound, is prepared by following raw materials,
Radix Astragali 30g, Radix Angelicae Sinensis 15g, pueraria lobata 15g, Poria cocos 15g, Rhizoma Atractylodis Macrocephalae 15g, root of Aucklandia lappa Decne 6g, wrinkled giant hyssop 15g, Chinese yam 15g, mulberry leaf 20g, horse
Bitterroot 15g, Ramulus euonymi 15g, coptis 8g, Radix Salviae Miltiorrhizae 15g, radix paeoniae rubra 15g, Rhizoma Chuanxiong 15g, prepared rehmannia root 15g, tuber of dwarf lilyturf 15g, Schisandra chinensis
6g, Radix Glycyrrhizae 8g.
The preparation method of above-mentioned Traditional Chinese medicine for decreasing blood sugar compound is:Take bulk pharmaceutical chemicals (the proportioning unit of above-mentioned parts by weight:Gram)
Capsule is prepared, concrete operations are:
1) each bulk pharmaceutical chemicals are weighed, it is spare;
2) it takes Radix Codonopsis, Schisandra chinensis, pueraria lobata, root of Aucklandia lappa Decne, wrinkled giant hyssop, Chinese yam, purslane, Radix Salviae Miltiorrhizae, radix paeoniae rubra, prepared rehmannia root to be uniformly mixed, adds 3 times
The water of weight boils by intense fire, is then cooked by slow fire 1 hour, filtrate and filter residue is collected by filtration;Water is added into filter residue, not filter
It subject to slag, boils by intense fire, is then cooked by slow fire 30 minutes, filtrate is collected by filtration;Merge above-mentioned filtrate twice, after cooling, concentration
At the medicinal extract that density is 1.1-1.2g/ml;After 80 DEG C of drying, it is ground into powder, as compound A;
3) take Radix Astragali, Radix Angelicae Sinensis, Radix Ophiopogonis, mulberry leaf, Poria cocos, Rhizoma Atractylodis Macrocephalae, Ramulus euonymi, the coptis, Rhizoma Chuanxiong, Radix Glycyrrhizae that 70% ethyl alcohol is added to impregnate 0.5-
1.5 hours, extraction was twice, 1-2 hours each, merged extracting solution, and filtration is condensed into the medicinal extract that relative density is 1.2, dry
After crush, obtain compound B;
4) compound A and compound B are mixed evenly, capsule product is made in sterilization.
Take mode:It is oral, three times per day, before meals half an hour take, each 0.5g, two weeks are as a treatment course.
Embodiment 2:
A kind of Traditional Chinese medicine for decreasing blood sugar compound, is prepared by following raw materials,
Radix Astragali 50g, Radix Angelicae Sinensis 25g, pueraria lobata 25g, Poria cocos 25g, Rhizoma Atractylodis Macrocephalae 25g, root of Aucklandia lappa Decne 15g, wrinkled giant hyssop 25g, Chinese yam 25g, mulberry leaf 40g,
Purslane 25g, Ramulus euonymi 25g, coptis 12g, Radix Salviae Miltiorrhizae 25g, radix paeoniae rubra 25g, Rhizoma Chuanxiong 25g, prepared rehmannia root 25g, tuber of dwarf lilyturf 25g, the five tastes
Sub- 15g, Radix Glycyrrhizae 12g.
Preparation and instructions of taking such as embodiment 1.
Embodiment 3:
A kind of Traditional Chinese medicine for decreasing blood sugar compound, is prepared by following raw materials,
Radix Astragali 40g, Radix Angelicae Sinensis 20g, Radix Codonopsis 20g, pueraria lobata 20g, Poria cocos 20g, Rhizoma Atractylodis Macrocephalae 20g, root of Aucklandia lappa Decne 10g, wrinkled giant hyssop 20g, Chinese yam 20g,
Mulberry leaf 30g, purslane 20g, Ramulus euonymi 20g, coptis 10g, Radix Salviae Miltiorrhizae 20g, radix paeoniae rubra 20g, Rhizoma Chuanxiong 20g, prepared rehmannia root 20g, Radix Ophiopogonis
20g, Schisandra chinensis 10g, Radix Glycyrrhizae 10g.
Preparation and instructions of taking such as embodiment 1.
Embodiment 4:Experiment of Zoology
Experiment process:
SPF grades of 8 week old Wistar male rats 90 are selected at random, are provided by Shandong University's Animal Lab., 200 ± 20g of weight,
Credit number is:SCXK (Shandong) 2013-0009.
Ad lib and drinking-water, animal house temperature are controlled in 22-26 DEG C of temperature, humidity 55%, illumination 12/24h.Adaptability
Raising 1 week, blood glucose are to measure weight in normal range (NR).
It is randomly divided into blank group(n=10)And modeling group(n=80).Blank group gives standard rat chow, and modeling group gives high sugar
High lipid food 6 weeks detects fasting blood-glucose(FBG), triglycerides(TG), total cholesterol(TC), low-density lipoprotein(LDL), it is high
Density lipoprotein(HDL).
Modeling group rat high glucose and high fat forage feed fasting 12h after 6 weeks, gives streptozotocin(It is dissolved in 0.1mol/L in 0 DEG C
The sodium citrate buffer solution of pH=4.4, final concentration of 10mg/mL are injected by 40mg/kg disposable celiacs);Control group injection etc.
The buffer solution of dosage.Tail vein blood after 72 hours, continuously to be determined as diabetes big by random blood sugar >=16.7mmol/L person three times
Mouse.
Choose the successful rat 60 of modeling, be randomly divided into 3 groups, every group 20, i.e., model group (not applying any drug),
3 medicine group 10mg/Kg of the embodiment of the present invention, control drug group:Using melbine (10mg/kg), method of application be it is oral,
Daily sooner or later before meals half when take.Continuous take is detected after two weeks;Blood glucose is monitored again after being discontinued 10 days.
After testing:Control drug group and medicine group fasting blood-glucose of the present invention decreased significantly, and drug of the present invention is obviously good
After control drug group, stopping ten days, medicine group of the present invention does not have a rebound substantially, referring specifically to following table.
Embodiment 5:Clinical case
Data and method:General information outpatient service diabetes B belongs to Qi deficiency blood stasis type patient totally 56, wherein man 30, female 26
Example, patient age 50-80 Sui, fasting blood-glucose (FPG) and 2h-plasma glucose (2hPG) are sharply increased.It takes of the invention real
After two courses for the treatment of of drug for applying the preparation of example 3, above-mentioned biochemical indicator is detected.
It cures:FPG < 6.1mmol/L, 2h blood glucose (2hPG) < 8.0mmol/L;
Effectively:Fasting blood-glucose (FPG), 2h-plasma glucose (2hPG) make moderate progress, but not up to normal level;
In vain:Fasting blood-glucose (FPG), postprandial 2h blood glucose (2hPG) nothing are substantially change.
Therapeutic effect:Healing 43, effective 12, invalid 1, total effective rate 98%.
Embodiment 6:Model case
Lin, female, 53 years old, pale white complexion, body was tired weak, and the few lazy speech of gas, dry is drunk more, shortness of breath, spontaneous perspiration, dynamic then aggravate, the heart
It is tired, blurred vision.Tongue is dark red, and tongue is thin to lack Tianjin, indentations at the margin of the tongue, deep thready pulse in vain.Fasting blood-glucose 10.8mmol/L, 2h-plasma glucose
14.0mmol/L is diagnosed as diabetes B.The Chinese herbal compounds for giving embodiment 3, after taking 2 course for the treatment of, symptom mitigates, after
Continuous to take 1 course for the treatment of consolidation, fasting blood-glucose is less than 7.0mmol/L.It is visited after half a year, blood glucose value is normal.
Mr. Wang, male, 67 years old, diabetes B medical history 7 years, existing dim complexion, weak, dry mostly drink, shortness of breath, hidrosis were received
Difference, blurred vision, double lower limb is numb, and tongue is dark.Indentations at the margin of the tongue, tongue is thin white, and deeptensepulse is puckery.Fasting blood-glucose 11.4mmol/L, after the meal
2h blood glucose 16.0mmol/L now take orally Glimepiride 1, QD, melbine 0.5TID.It gives and implements on the basis of original drug
The Chinese herbal compounds of example 1, after taking 2 course for the treatment of, symptom mitigates, and continues to take 1 course for the treatment of consolidation, fasting blood-glucose is less than 7.Later
Multiple follow-up, glucostasis is in 7.0mmo/L or less.
Claims (8)
1. a kind of Traditional Chinese medicine for decreasing blood sugar, it is characterized in that, it is mixed by the raw material of following parts by weight:30-50 parts of Radix Astragali, Radix Angelicae Sinensis
15-25 parts, 15-25 parts of pueraria lobata, 15-25 parts of Poria cocos, 15-25 parts of Rhizoma Atractylodis Macrocephalae, 6-15 parts of root of Aucklandia lappa Decne, 15-25 parts of wrinkled giant hyssop, Chinese yam 15-25
Part, 20-40 parts of mulberry leaf, 15-25 parts of purslane, 15-25 parts of Ramulus euonymi, 8-12 parts of the coptis, 15-25 parts of Radix Salviae Miltiorrhizae, radix paeoniae rubra 15-25
Part, 15-25 parts of Rhizoma Chuanxiong, 15-25 parts of prepared rehmannia root, 15-25 parts of the tuber of dwarf lilyturf, 6-15 parts of Schisandra chinensis, 8-12 parts of Radix Glycyrrhizae.
2. Traditional Chinese medicine for decreasing blood sugar according to claim 1, it is characterized in that, it is mixed by the raw material of following parts by weight:
30-50 parts of Radix Astragali, 15-25 parts of Radix Angelicae Sinensis, 15-25 parts of pueraria lobata, 15-25 parts of Poria cocos, 15-25 parts of Rhizoma Atractylodis Macrocephalae, 6-15 parts of root of Aucklandia lappa Decne, wrinkled giant hyssop
15-25 parts, 15-25 parts of Chinese yam, 20-40 parts of mulberry leaf, 15-25 parts of purslane, 15-25 parts of Ramulus euonymi, 8-12 parts of the coptis, Radix Salviae Miltiorrhizae
15-25 parts, 15-25 parts of radix paeoniae rubra, 15-25 parts of Rhizoma Chuanxiong, 15-25 parts of prepared rehmannia root, 15-25 parts of the tuber of dwarf lilyturf, 6-15 parts of Schisandra chinensis, Radix Glycyrrhizae
8-12 parts.
3. Traditional Chinese medicine for decreasing blood sugar according to claim 1, it is characterised in that:The Chinese medicine is capsule.
4. the preparation method of Traditional Chinese medicine for decreasing blood sugar according to claim 1, it is characterized in that, include the following steps:(1)Claim respectively
Each bulk pharmaceutical chemicals are taken, it is spare;(2)Take Radix Codonopsis, Schisandra chinensis, pueraria lobata, root of Aucklandia lappa Decne, wrinkled giant hyssop, Chinese yam, purslane, Radix Salviae Miltiorrhizae, radix paeoniae rubra, prepared rehmannia root
It is uniformly mixed, adds water to cook twice, be collected by filtration after filtrate and merge filtrate twice, medicinal extract is condensed into after cooling, then powder after drying
It is broken into powder, obtains compound A;(2)Radix Astragali, Radix Angelicae Sinensis, Radix Ophiopogonis, mulberry leaf, Poria cocos, Rhizoma Atractylodis Macrocephalae, Ramulus euonymi, the coptis, Rhizoma Chuanxiong, Radix Glycyrrhizae are taken,
Ethyl alcohol is added to impregnate, extraction twice, merges extracting solution, filters, is condensed into medicinal extract, crushed after being dried obtains compound B;(4)It will be compound
Object A and compound B is uniformly mixed, and capsule product is made in sterilization.
5. the preparation method of Traditional Chinese medicine for decreasing blood sugar according to claim 4, it is characterised in that:Step(2)In, it decocts twice
In, for the first time plus the water of 3 times of weight boils by intense fire, is then cooked by slow fire 1 hour, filtrate and filter residue is collected by filtration;Into filter residue
Water is added, regards no filter slag as criterion, boils by intense fire, be then cooked by slow fire 30 minutes, filtrate is collected by filtration.
6. the preparation method of Traditional Chinese medicine for decreasing blood sugar according to claim 4, it is characterised in that:Step(2)In, filtrate cooling
The medicinal extract that density is 1.1-1.2g/mL is condensed into afterwards to be ground into powder after drying at 80 DEG C, obtain compound A.
7. the preparation method of Traditional Chinese medicine for decreasing blood sugar according to claim 4, it is characterised in that:Step(3)In, add quality dense
The ethyl alcohol of degree 70% impregnates 0.5-1.5 hours, and extraction is twice, 1-2 hours each, merges extracting solution.
8. the preparation method of Traditional Chinese medicine for decreasing blood sugar according to claim 4, it is characterised in that:Step(3)In, the phase of medicinal extract
It is 1.2 to density.
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| CN101396518A (en) * | 2007-09-29 | 2009-04-01 | 马万里 | Traditional Chinese medicine composition for treating diabetes and complication |
| CN103690740A (en) * | 2013-12-03 | 2014-04-02 | 刘静 | Traditional Chinese medicinal formula for treating diabetes mellitus |
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| CN101396518A (en) * | 2007-09-29 | 2009-04-01 | 马万里 | Traditional Chinese medicine composition for treating diabetes and complication |
| CN103690740A (en) * | 2013-12-03 | 2014-04-02 | 刘静 | Traditional Chinese medicinal formula for treating diabetes mellitus |
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