CN108653552B - Traditional Chinese medicine for clearing lung and relieving cough - Google Patents
Traditional Chinese medicine for clearing lung and relieving cough Download PDFInfo
- Publication number
- CN108653552B CN108653552B CN201810955592.0A CN201810955592A CN108653552B CN 108653552 B CN108653552 B CN 108653552B CN 201810955592 A CN201810955592 A CN 201810955592A CN 108653552 B CN108653552 B CN 108653552B
- Authority
- CN
- China
- Prior art keywords
- parts
- cough
- lung
- traditional chinese
- chinese medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 206010011224 Cough Diseases 0.000 title claims abstract description 165
- 239000003814 drug Substances 0.000 title claims abstract description 83
- 210000004072 lung Anatomy 0.000 title abstract description 70
- 210000000582 semen Anatomy 0.000 claims abstract description 24
- 239000000203 mixture Substances 0.000 claims abstract description 23
- 235000004347 Perilla Nutrition 0.000 claims abstract description 19
- 244000124853 Perilla frutescens Species 0.000 claims abstract description 19
- 241000931705 Cicada Species 0.000 claims abstract description 12
- 244000303040 Glycyrrhiza glabra Species 0.000 claims description 19
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims description 19
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims description 19
- 235000011477 liquorice Nutrition 0.000 claims description 19
- 244000144725 Amygdalus communis Species 0.000 claims description 14
- 235000003893 Prunus dulcis var amara Nutrition 0.000 claims description 13
- 240000000691 Houttuynia cordata Species 0.000 claims description 12
- 244000248416 Fagopyrum cymosum Species 0.000 claims description 11
- 244000274050 Platycodon grandiflorum Species 0.000 claims description 10
- 241000628997 Flos Species 0.000 claims description 9
- 235000006753 Platycodon grandiflorum Nutrition 0.000 claims description 9
- 240000004534 Scutellaria baicalensis Species 0.000 claims description 9
- 235000017089 Scutellaria baicalensis Nutrition 0.000 claims description 9
- 241000218378 Magnolia Species 0.000 claims description 8
- 240000000249 Morus alba Species 0.000 claims description 8
- 235000008708 Morus alba Nutrition 0.000 claims description 8
- 240000005790 Oroxylum indicum Species 0.000 claims description 6
- 235000012920 Oroxylum indicum Nutrition 0.000 claims description 6
- 240000000377 Tussilago farfara Species 0.000 claims description 6
- 235000004869 Tussilago farfara Nutrition 0.000 claims description 6
- 235000021282 Sterculia Nutrition 0.000 claims description 5
- 240000001058 Sterculia urens Species 0.000 claims description 5
- 229940059107 sterculia Drugs 0.000 claims description 5
- 235000013717 Houttuynia Nutrition 0.000 claims description 4
- 244000081426 Ranunculus ficaria Species 0.000 claims description 4
- 235000002226 Ranunculus ficaria Nutrition 0.000 claims description 4
- 235000013399 edible fruits Nutrition 0.000 claims description 4
- 241000758794 Asarum Species 0.000 claims description 3
- 241000334154 Isatis tinctoria Species 0.000 claims description 2
- 208000013116 chronic cough Diseases 0.000 abstract description 12
- 230000001717 pathogenic effect Effects 0.000 abstract description 9
- 244000018633 Prunus armeniaca Species 0.000 abstract description 5
- 235000009827 Prunus armeniaca Nutrition 0.000 abstract description 5
- 208000011580 syndromic disease Diseases 0.000 description 39
- 201000007100 Pharyngitis Diseases 0.000 description 26
- 208000015181 infectious disease Diseases 0.000 description 26
- 210000003800 pharynx Anatomy 0.000 description 25
- 206010068319 Oropharyngeal pain Diseases 0.000 description 24
- 208000003251 Pruritus Diseases 0.000 description 24
- 201000010099 disease Diseases 0.000 description 19
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 19
- 210000002784 stomach Anatomy 0.000 description 18
- 208000006673 asthma Diseases 0.000 description 17
- 230000007803 itching Effects 0.000 description 16
- 238000000034 method Methods 0.000 description 16
- 208000024891 symptom Diseases 0.000 description 15
- 206010062717 Increased upper airway secretion Diseases 0.000 description 12
- 206010039101 Rhinorrhoea Diseases 0.000 description 12
- 241000245665 Taraxacum Species 0.000 description 12
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 description 12
- 208000010753 nasal discharge Diseases 0.000 description 12
- 208000026435 phlegm Diseases 0.000 description 12
- 230000004069 differentiation Effects 0.000 description 11
- 230000000694 effects Effects 0.000 description 10
- 238000003745 diagnosis Methods 0.000 description 9
- 235000013719 Houttuynia cordata Nutrition 0.000 description 8
- 206010006451 bronchitis Diseases 0.000 description 7
- 229940079593 drug Drugs 0.000 description 7
- 239000002398 materia medica Substances 0.000 description 7
- 206010036790 Productive cough Diseases 0.000 description 6
- 230000036528 appetite Effects 0.000 description 6
- 235000019789 appetite Nutrition 0.000 description 6
- 238000009472 formulation Methods 0.000 description 6
- 210000004185 liver Anatomy 0.000 description 6
- 244000052769 pathogen Species 0.000 description 6
- 230000008506 pathogenesis Effects 0.000 description 6
- 240000007126 Citrus medica var. sarcodactylis Species 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 208000017574 dry cough Diseases 0.000 description 5
- 238000010926 purge Methods 0.000 description 5
- 208000005392 Spasm Diseases 0.000 description 4
- 230000002411 adverse Effects 0.000 description 4
- 230000013872 defecation Effects 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 208000024794 sputum Diseases 0.000 description 4
- 210000003802 sputum Anatomy 0.000 description 4
- 241000721047 Danaus plexippus Species 0.000 description 3
- 230000009545 invasion Effects 0.000 description 3
- 230000000630 rising effect Effects 0.000 description 3
- 231100000331 toxic Toxicity 0.000 description 3
- 230000002588 toxic effect Effects 0.000 description 3
- 229940126680 traditional chinese medicines Drugs 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 241000596154 Belamcanda Species 0.000 description 2
- 206010006458 Bronchitis chronic Diseases 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 241000209140 Triticum Species 0.000 description 2
- 235000021307 Triticum Nutrition 0.000 description 2
- 206010070488 Upper-airway cough syndrome Diseases 0.000 description 2
- 208000031975 Yang Deficiency Diseases 0.000 description 2
- 208000031971 Yin Deficiency Diseases 0.000 description 2
- 230000000954 anitussive effect Effects 0.000 description 2
- 229940124584 antitussives Drugs 0.000 description 2
- 208000007451 chronic bronchitis Diseases 0.000 description 2
- 201000004897 cough variant asthma Diseases 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical compound C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 description 2
- 208000001780 epistaxis Diseases 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 210000002216 heart Anatomy 0.000 description 2
- 239000002085 irritant Substances 0.000 description 2
- 231100000021 irritant Toxicity 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 230000001314 paroxysmal effect Effects 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 241001116477 Adenophora triphylla Species 0.000 description 1
- 208000000884 Airway Obstruction Diseases 0.000 description 1
- 235000011437 Amygdalus communis Nutrition 0.000 description 1
- 241000132012 Atractylodes Species 0.000 description 1
- 206010063659 Aversion Diseases 0.000 description 1
- 241000167854 Bourreria succulenta Species 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 241000490229 Eucephalus Species 0.000 description 1
- 241000219051 Fagopyrum Species 0.000 description 1
- 235000009419 Fagopyrum esculentum Nutrition 0.000 description 1
- 241001547127 Fritillaria cirrhosa Species 0.000 description 1
- 241000935235 Fritillaria meleagris Species 0.000 description 1
- 208000008454 Hyperhidrosis Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 241001598107 Imperata Species 0.000 description 1
- 241000334160 Isatis Species 0.000 description 1
- 206010062575 Muscle contracture Diseases 0.000 description 1
- 206010028748 Nasal obstruction Diseases 0.000 description 1
- 201000005702 Pertussis Diseases 0.000 description 1
- 235000006751 Platycodon Nutrition 0.000 description 1
- 241001619461 Poria <basidiomycete fungus> Species 0.000 description 1
- 206010057190 Respiratory tract infections Diseases 0.000 description 1
- 241000612118 Samolus valerandi Species 0.000 description 1
- 241001571446 Scaphium scaphigerum Species 0.000 description 1
- 241001121987 Scrophularia ningpoensis Species 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- 206010046306 Upper respiratory tract infection Diseases 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 235000020224 almond Nutrition 0.000 description 1
- 229940124350 antibacterial drug Drugs 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 239000010231 banlangen Substances 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 206010006514 bruxism Diseases 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 235000019693 cherries Nutrition 0.000 description 1
- 238000011976 chest X-ray Methods 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 208000006111 contracture Diseases 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000002996 emotional effect Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 230000037315 hyperhidrosis Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 230000000622 irritating effect Effects 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 230000033001 locomotion Effects 0.000 description 1
- 238000010197 meta-analysis Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 229930189914 platycodon Natural products 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 208000013220 shortness of breath Diseases 0.000 description 1
- 239000000779 smoke Substances 0.000 description 1
- 230000000391 smoking effect Effects 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 206010044008 tonsillitis Diseases 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 230000010415 tropism Effects 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
- A61K36/195—Strobilanthes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/342—Adenophora
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/346—Platycodon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/428—Trichosanthes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/808—Scrophularia (figwort)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
- A61K36/855—Clerodendrum, e.g. glorybower
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8966—Fritillaria, e.g. checker lily or mission bells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Insects & Arthropods (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a traditional Chinese medicine for clearing lung and relieving cough, which comprises 5-10g of cortex mori radicis; 3-10 parts of bitter apricot seeds; 5-15g of perilla seeds; and at least two of 1-3g of bulbus fritilariae, 2-10g of cicada slough and 2-6g of semen oroxyli. The Chinese medicinal composition can be used for treating chronic cough in children, and is especially effective in treating cough caused by pathogenic wind and lung stagnation.
Description
Technical Field
The invention relates to the field of traditional Chinese medicines, in particular to traditional Chinese medicine treatment for cough after infection, and especially relates to traditional Chinese medicine treatment for cough after infection of wind pathogen latent lung syndrome.
Background
Cough is one of the most common symptoms of respiratory disease in children. Children's cough is classified into acute cough (course within 2 weeks), persistent cough (course between 2 and 4 weeks) and chronic cough (course over 4 weeks) according to the length of the course. Chronic cough can be classified into specific cough, which means that cough is accompanied by other symptoms or signs that can suggest specific etiology, and non-specific cough, i.e., cough is one of these well-defined disease symptoms; the latter refers to chronic cough with cough as the main or only manifestation, and no obvious abnormality is seen in chest X-ray film. The Chinese guidelines for the diagnosis and treatment of chronic cough in children (revised in 2013, J. Chinese pediatrics, 2014, 52 (3): 184-188.) indicate that the first 3 causes of chronic cough in children are Cough Variant Asthma (CVA), Upper Airway Cough Syndrome (UACS) and post-respiratory cough (PIC). The children infected with the cough has high prevalence rate and long course of disease, which is a difficult problem for troubling families and doctors of children. In the present clinical application, many children are misdiagnosed as "chronic bronchitis" or "bronchitis" for a long time, and the treatment is ineffective by using a large amount of antibacterial drugs, or various examinations are repeatedly performed due to unclear diagnosis, so that the pain of the children is increased, and the economic burden is increased. With the disease gradually recognized and concerned, it is urgent to find a quick and effective treatment for cough after infection. In recent years, studies on cough after infection are quite numerous, but the exact pathogenesis of the cough is still unclear, so that the treatment of the cough after infection by western medicine is lack of well-known effective medicines, while a unique syndrome differentiation and treatment system of traditional Chinese medicine has remarkable advantages in the aspect of treating the cough after infection by children, and the studies on the cough after infection by the traditional Chinese medicine are gradually increased in recent years (observation of curative effect of the prescription granules for relieving cough and asthma for treating the cough with phlegm-damp accumulation in the lung after infection by the children by using the combination of the Guolin and the chest-coating powder [ D ]. Hubei: Hubei university of traditional Chinese medicine in 2015; Liuyanmei, Meta analysis of cough after treatment by the traditional Chinese medicine and Wanyuguang teaching treatment experience of traditional Chinese medicine for summarizing [ D ]. Beijing: Beijing university of traditional Chinese medicine in 2016.
The aforementioned "Chinese guideline for diagnosing and treating chronic cough in children" is a revised version of the cooperative group of chronic cough in China medical institute of pediatrics respiratory department in 2013 on 2008 "guideline (trial) for diagnosing and treating chronic cough in children" (China pediatric journal, 2008,46(2): 104-) -107). The traditional Chinese medicine treatment of the chronic cough of children is not mentioned in the two guidelines, the traditional Chinese medicine treatment of the cough is increased until 2015, namely the diagnosis and treatment guideline (2015) for the cough (Chinese tuberculosis and journal of respiration, 2016,39(5):323 + 354), and the cough syndrome type, treatment method and prescription are definitely provided, wherein the cough syndrome type, treatment method and prescription are specifically provided, and the cough syndrome type, treatment method and prescription comprise 7 syndromes of lung yin deficiency syndrome, lung kidney yang deficiency syndrome, stomach qi upward adverse syndrome, liver fire invasion lung syndrome, wind evil lung syndrome, wind cold invasion lung syndrome and wind-heat invasion lung syndrome. The interpretation of "TCM" (TCM) (Zhi Zhu Zhi (2015) for diagnosis and treatment of cough) (Zhi Yao, Liu Jian. Anjing TCM 2016,9(6):699-701) indicates that the addition of more than 1400 Chinese-medicinal related contents to the Zhi Zhu (guide) for diseases in Western medicine in China is the first time. The method reflects the academic inclusion of Chinese western medicine and the academic wind of practical affairs, and reflects the current situation of coexistence of Chinese and western medicine systems and the fact that the traditional Chinese medicine has unique curative effect in the field to a certain extent. Seven clinical common syndromes introduced in the manual are the core of the traditional Chinese medicine content in the manual, and the traditional Chinese medicine has six common syndromes listed in the traditional textbook acknowledged by the traditional Chinese medicine world (lung yin deficiency syndrome, lung kidney yang deficiency syndrome, adverse rising of stomach qi, liver fire attacking lung syndrome, wind-cold attacking lung syndrome and wind-heat attacking lung syndrome), and also has the syndrome of wind pathogen attacking lung (or wind-preponderance and contracture urgency) gradually recognized and accepted by the academic world in recent years, so that the important consensus and development concept of the traditional Chinese medicine world for bearing and innovation is realized.
Most of modern doctors have cough after infection in the categories of cough, chronic cough, dry cough, wind cough and stubborn cough in traditional Chinese medicine. The ancient literature was reviewed and the term post-infectious cough was not described, but there is little description therein consistent with the symptoms, progression, and progression of post-infectious cough. Su Wen & Feng Lun (Su Wen & Feng Lun): similar pathogenesis is pointed out, namely that the patients with the symptoms of lung wind, hyperhidrosis and aversion to wind … … cause cough and shortness of breath, and the patients are healed in the daytime and are even in the twilight. The "Nei Jing" (the internal classic) states that "itching occurs due to excessive wind", "no wind does not cause itching", "wind pathogen is a disease which is frequently changed due to excessive wind, and" spasm and urgency due to excessive wind ", which means that the etiology and pathogenesis of the disease characterized by itching are related to wind pathogen. The sui and Shi Chao Yuan Fang (treatise on all sources of disease) records: "wind cough, caused by cough, is not always the same", which is similar to the manifestation of cough after infection. The book of von jinggao secret records of Qing Dynasty von Mega considers: "these coughs are different from the syndrome of wind-heat invading the lung and fundamentally different from dry cough; the disease location involves the throat, lung organs and liver and heart; the pathological changes are characterized by the general manifestation of the adverse rising of lung qi, and have the self characteristics of wind movement, allergy, spasm and urgency of air passage, itching throat and choking as cough; the key points of the pathogenesis are that deficiency and excess are mixed, the exterior and interior are affected, the viscera are involved, and the deficiency of yin and blood and the wind-movement and qi-flow are combined. The Qing Dynasty high-age test is: the feature of itching and cough after infection is not in line with the clinical symptoms of cough caused by infection, i.e., cough caused by fire-heat ascending, fire getting over and smoking first, and smoke rushing towards the throat.
In clinical diagnosis and treatment, a large number of children with cough not cured after antibiotic is applied to control infection inevitably remain. According to research investigations (Hubei J.TCM, 2016, 38 (11): 34-35), cough after infection occurs in about 11% -25% of patients with a history of upper respiratory tract infection, and the incidence rate is as high as 25% -50% in the epidemic season. The inventor discovers that a considerable part of children with cough after infection has unique and similar symptoms during clinical symptoms, and the symptoms are mainly manifested as paroxysmal dry cough or only a small amount of white sticky phlegm, severe cough, even spasmodic cough and irregular cough, often cough caused by pharynx itch and difficult control, cough induced or aggravated by cold and hot air, pungent smell or speaking, emotional agitation and the like, and the symptoms are highly matched with pathogenic characteristics of wind evil, such as 'wind-strong line change', 'wind-strong itching', 'wind-strong spasm' and the like. The key points of the pathogenesis of the cough are that the initial disease is wind evil attacking the lung and the qi activity is disordered, the later exterior syndrome is removed, only the wind evil stays in the lung for a long time, the lung fails to disperse and descend, the qi activity is unfavorable, and the lung qi is reversed to cough. The cold and heat symptoms are not prominent in clinical manifestations, but there are prominent symptoms such as sudden onset, paroxysmal cough, itching throat, etc.
The children and family members have great diagnosis willingness, and the clinical application of the children needs to pay enough attention, so that the finding of a simple, cheap and popular diagnosis and treatment scheme is of great significance. The inventor of the invention refers to the theory related to traditional Chinese medicine and completes the invention through a large amount of clinical practices of dialectical treatment.
The invention aims to provide a traditional Chinese medicine composition for clearing lung and relieving cough, which aims at chronic cough of children, in particular to cough caused by wind pathogen hidden in lung.
Disclosure of Invention
The invention provides a traditional Chinese medicine composition for clearing lung and relieving cough, which comprises the following traditional Chinese medicines:
5-10g of cortex mori; bitter apricot seeds 3-10 g; 5-15g of perilla seeds; and
at least two of 1-3g of bulbus fritillariae cirrhosae, 2-10g of cicada slough and 2-6g of semen oroxyli.
In a preferred embodiment of the invention, the dosage of each traditional Chinese medicine is respectively as follows: 5-8g of white mulberry root-bark, 3-8g of bitter almond, 5-10g of perilla fruit, 1-2g of bulbus fritilariae, 2-4g of cicada slough and 2-4g of oroxylum indicum.
In a more preferred embodiment of the present invention, the dosage of each Chinese medicine is: 5-6g of white mulberry root-bark, 3-6g of bitter almond, 6-10g of perilla seed, 1g of bulbus fritilariae, 3g of cicada slough and 3g of oroxylum indicum.
In a more preferred embodiment of the present invention, the present invention further comprises one or more of the following traditional Chinese medicines: 2-6g of scutellaria baicalensis, 2-6g of platycodon grandiflorum, 2-10g of magnolia flower and 2-6g of raw liquorice.
In the embodiment, the dosage of each Chinese medicinal material can be Scutellariae radix 2-6g, radix Platycodi 2-3g, flos Magnoliae 5-6g, and Glycyrrhrizae radix 2-4 g.
In other embodiments of the present invention, one or more of the following Chinese medicinal materials may be further included: 6-15g of wild buckwheat rhizome, 6-15g of figwort root, 6-15g of dyers woad leaf, 6-10g of boat-fruited sterculia seed, 6-15g of heartleaf houttuynia herb and 6-10g of common coltsfoot flower.
The invention provides a treatment scheme for clearing lung heat and relieving cough, dispelling wind and relieving sore throat according to the etiology and pathogenesis characteristics of cough caused by wind pathogen invading lung and provides a traditional Chinese medicine for clearing lung heat and relieving cough.
The lung-heat clearing and cough relieving traditional Chinese medicine takes the root bark of white mulberry as a monarch, the bitter apricot seeds and the perilla seeds as ministers, the bulbus fritillariae cirrhosae and the periostracum cicadae as assistants, and the oroxylum indicum as a guide.
The monarch drug, cortex mori radicis sweet and cold, mainly enters lung channels, is not dry and not rigid, but can purge lung heat without hurting delicate organs, clear lung heat and relieve cough without hurting vital qi;
perilla seed, fructus Perillae, being pungent and warm in flavor, enters lung and spleen meridians, lowers qi, relieves asthma, moistens lung and relieves cough. The almond is bitter in taste and slightly warm in taste, enters lung and large intestine channels, has the functions of ventilating lung qi and relieving cough and asthma, and has the functions of regulating lung qi and dispersing lung qi together with qi-descending medicines such as the white mulberry root-bark, the perilla fruit and the like. In the section of materia medica Biaoshu (materia medica Biaori), bitter apricot kernels have the functions of lowering qi, and lowering qi, so as to eliminate phlegm and relieve cough, and the section of materia medica Shuyi (materia medica Shuyi) is: su Zi mainly lowers blood pressure, and Wei Xin … … decides asthma. Both of them can direct qi downward, resolve phlegm and stop cough, and they are warm in nature, and can prevent excessive cold by matching with the monarch drug cold property, so as to avoid damage to spleen and stomach, and they are used as ministerial drugs.
Bulbus Fritillariae Cirrhosae and periostracum Cicadae as adjuvant drugs. Fritillary bulb: the mulberry leaf tea has cold nature, enters lung and heart channels, has the functions of clearing heat, eliminating phlegm, relieving depression and dissipating stagnation, and has the effects of clearing lung and relieving cough when being used together with the mulberry bark. Cicada slough: sweet taste, cold nature, lung and liver meridian tropism, light weight and thin taste, good lung qi opening and dispersing, all wind evil dispelling, heat removing, wind dispelling and spasm stopping, and can disperse wind evil lingering on the exterior for a long time and relieve sore throat and itching.
The oroxylum indicum enters lung, liver and stomach channels, has the effects of clearing lung-heat and relieving sore throat, soothing liver and harmonizing stomach, is recorded in Chinese medicine dictionary to be an antitussive and a dry bronchitis in treatment of acute and chronic bronchitis, sore throat and tonsillitis, and is recorded in modern practical Chinese medicine dictionary to be an antitussive and a pertussis.
For the combined symptoms of pharyngeal discomfort, nasal obstruction and nasal discharge, Huang Qin excels in clearing the upper-jiao fire and clearing the lung, and introduces herbs into the lung meridian; jie Geng is good at promoting lung qi and is a special herb for lung meridian; flos Magnoliae has effects of dispelling pathogenic wind and cold, and relieving stuffy nose; unprocessed gan Cao clears throat and purges fire, recorded in Ben Cao Cuo Yao (materia Medica) to obtain unprocessed Jie Geng Qing Yan … … for purging fire. Therefore, the lung-heat clearing and cough relieving traditional Chinese medicine composition can also comprise one or more of scutellaria baicalensis, platycodon grandiflorum, magnolia flower and raw liquorice.
Aiming at the combined symptoms of cough with phlegm, sore throat and the like, the golden buckwheat has the efficacies of clearing away heat and toxic material, eliminating carbuncle and relieving sore throat, so that the Chinese patent of 'treating pharyngitis and throat wind and throat toxin' in 'Ben Cao gang mu Shi Yi'; xuan Shen has the actions of clearing heat, cooling blood and removing toxicity, so it is recorded in Ben Cao Pin Hui Yao (materia Medica Bo essence essentials) in order to eliminate swelling of throat and purge root-free or fire; folium Isatidis has effects of clearing away heat and toxic materials and relieving sore throat, and can be used for treating toxic heat and sore throat; boat-fruited sterculia seed has the efficacies of clearing heat, relieving sore throat, moistening lung and making sound, and the book of materia medica justice records: "good at opening and lifting lung qi and unblocking and purging skin and hair"; the cordate houttuynia has the effects of clearing heat and removing toxicity and is good at clearing lung heat; flos Farfarae has effects of moistening lung, descending qi, relieving cough, and eliminating phlegm, and it is said from Shen nong's herbal Jing that it is "treating cough, adverse rising qi, good asthma, and pharyngitis". Therefore, the lung-heat clearing and cough relieving traditional Chinese medicine composition can also comprise one or more of wild buckwheat rhizome, figwort root, indigowoad leaf, boat-fruited sterculia seed, heartleaf houttuynia herb and common coltsfoot flower.
The lung-heat clearing and cough relieving traditional Chinese medicine formula combines the medicines, combines cold and warm, simultaneously exerts functions of dispersing and descending, supplements each other, and has the functions of clearing heat and relieving cough, dispelling wind and relieving sore throat, so that the lung is clear, the lung qi is purified, the wind dispels heat, the qi is smooth and itchy, and the cough is self-healed.
The taking method comprises the following steps: the Chinese medicinal composition can be decocted in water twice a day and then taken after residue is removed; or decocting with water for several days, and packaging into bags, one bag for warm administration; or making the conventional formulation into extract or further making into granule, and taking with warm water.
Detailed Description
The present invention will be described more specifically and further illustrated with reference to typical cases, which are by no means intended to limit the present invention.
Case 1
Some Lu, male, 6 years old, Jiading district of Shanghai city clinic number of traditional Chinese medicine hospital: 34934480
The patients with cough of 5 weeks were treated before the treatment in the hospital. The cough occurs frequently in the coming clinic, and the cough is less in sputum and not easy to be coughed out, the throat is itchy, the nose is thick, asthma is avoided, the stomach is not easy to be absorbed, and the stool is dry. The chest film is taken to prompt bronchitis, blood is checked to be within a normal range conventionally, the cough after infection is diagnosed in western medicine, the infantile cough is diagnosed in traditional Chinese medicine, the syndrome differentiation type is the syndrome of wind evil in the lung, the lung is cleared away to relieve cough, wind is dredged and the throat is relieved, and after the oral administration of the medicine disclosed by the invention for 7 days, the cough and throat itching can be stopped, no watery nasal discharge exists, the stomach is improved, and the excrement is normal.
The prescription of the disease example comprises the following medicinal components (unit: g):
6 parts of cortex mori radicis, 6 parts of bitter apricot seed, 10 parts of perilla seed, 2 parts of fritillaria cirrhosa, 5 parts of cicada slough, 3 parts of semen oroxyli, 6 parts of scutellaria baicalensis, 10 parts of wild buckwheat rhizome, 10 parts of figwort root, 10 parts of folium isatidis, 3 parts of raw liquorice, 6 parts of biond magnolia flower, 10 parts of medicated leaven, 6 parts of scaphium scaphigerum and 3 parts of.
Case 2
Wangzaiqi, female, 4 years old, Shanghai Jiading district traditional Chinese medicine hospital outpatient service number: 34666973
When the patient is treated for cough for 4 weeks, the patient is in an irritant dry cough without phlegm, and the patient is often induced by cold air, has itching throat, little nasal discharge, no asthma, poor appetite and good stool and urine. The western medicine diagnoses cough after infection, the traditional Chinese medicine diagnoses cough in children, the syndrome differentiation is the syndrome of wind evil in the lung, the treatment is to clear away the lung-heat and relieve cough, dispel wind and relieve sore throat, the oral administration of the medicine of the invention (formula one) is added and subtracted for 7 days, the cough is greatly reduced, no obvious sore throat and watery nasal discharge occur, and the stomach is improved. The second formulation was cured for 7 days.
The prescription of the disease example comprises the following medicinal components (unit: g):
the first method comprises the following steps:
6 parts of cortex mori radicis, 5 parts of bitter almond, 10 parts of perilla seeds, 1 part of bulbus fritillariae cirrhosae, 5 parts of cicada slough, 3 parts of semen oroxyli, 2 parts of scutellaria baicalensis, 3 parts of raw liquorice, 6 parts of biond magnolia flower, 15 parts of houttuynia cordata, 6 parts of semen lepidii, 6 parts of common coltsfoot flower, 10 parts of dandelion and 10 parts of medicated leaven.
And a second method:
6 parts of cortex mori radicis, 10 parts of fructus perillae, 1 part of bulbus fritillariae cirrhosae, 3 parts of periostracum cicadae, 3 parts of semen oroxyli, 3 parts of raw liquorice, 6 parts of biond magnolia flower, 10 parts of dandelion, 10 parts of medicated leaven, 10 parts of wild buckwheat rhizome, 3 parts of blackberry lily, 5 parts of fingered citron and 3 parts of radix sileris.
Case 3
Some leaf, female, 9 years old, jiading district of Shanghai, TCM hospital outpatient number: 34956172
The patients with cough for more than 4 weeks are treated before the treatment. Cough with itching throat, little sputum, difficult expectoration, watery nasal discharge, no asthma, good appetite for stomach, and convenient adjustment. The chest film is taken to indicate bronchitis, blood is checked in a normal range conventionally, cough after infection is diagnosed in western medicine, children cough is diagnosed in traditional Chinese medicine, syndrome differentiation and type differentiation are caused by wind evil in the lung, lung heat is cleared and cough is stopped, wind is dispelled and throat is relieved, and the cough and throat itching is obviously improved and less nasal discharge is caused when the medicine is orally taken for 7 days. The second formulation was cured for 7 days.
The prescription of the disease example comprises the following medicinal components (unit: g):
the first method comprises the following steps:
10 parts of cortex mori radicis, 10 parts of bitter almond, 15 parts of perilla seeds, 3 parts of bulbus fritillariae cirrhosae, 10 parts of periostracum cicadae, 6 parts of semen oroxyli, 3 parts of scutellaria baicalensis, 6 parts of raw liquorice, 15 parts of houttuynia cordata, 10 parts of semen lepidii, 15 parts of folium isatidis, 10 parts of flos farfarfarae, 10 parts of flos magnoliae and 10 parts of radix scrophulariae.
And a second method:
6 parts of cortex mori radicis, 15 parts of fructus perillae, 2 parts of bulbus fritillariae cirrhosae, 6 parts of periostracum cicadae, 3 parts of semen oroxyli, 6 parts of raw liquorice, 15 parts of houttuynia cordata, 10 parts of flos farfarae, 6 parts of flos magnoliae, 10 parts of radix scrophulariae, 10 parts of dandelion, 10 parts of boat-fruited sterculia seed and 6 parts of platycodon grandi.
Case 4
Some strictly, women, 7 years old, jiading district of Shanghai city, outpatient service number of traditional Chinese medicine hospital: 34560596
The patients with cough of 6 weeks were treated before the treatment in the hospital. Cough frequently occurs in the coming clinic, the cough is difficult, the throat is itchy, no nasal discharge and asthma occur, the stomach is not shaken, and the defecation is normal. The traditional Chinese medicine diagnoses cough after infection, the traditional Chinese medicine diagnoses cough in children, the syndrome differentiation is the syndrome of wind evil in the lung, the treatment is to clear away the lung-heat and relieve cough, dispel wind and relieve sore throat, and after the oral administration of the medicine disclosed by the invention is added or reduced for 7 days, the cough and the sore throat are stopped, and the stomach is improved.
The prescription of the disease example comprises the following medicinal components (unit: g):
6 parts of cortex mori radicis, 10 parts of bitter almond, 10 parts of perilla seeds, 3 parts of bulbus fritillariae cirrhosae, 6 parts of periostracum cicada, 6 parts of semen oroxyli, 3 parts of scutellaria baicalensis, 6 parts of raw liquorice, 10 parts of houttuynia cordata, 10 parts of dandelion and 10 parts of medicated leaven.
Case 5
Some Zhu, woman, 6 years old, Jiading district of Shanghai, TCM hospital outpatient number: 34727747
The patient is treated for cough for 5 weeks, and the cough symptoms are not cured repeatedly after the patient is treated for a plurality of times in an outpatient department. Cough aggravated by repeated cold in the recent day, cough paroxysmal action, white and sticky phlegm, throat itching, no watery nasal discharge and asthma, general appetite of stomach and convenient adjustment. The western medicine diagnoses cough after infection, the traditional Chinese medicine diagnoses cough in children, the syndrome differentiation is the syndrome of wind evil in the lung, the treatment is to clear away the lung-heat and relieve cough, dispel wind and relieve sore throat, and after the oral administration of the medicine disclosed by the invention is added or reduced for 7 days, the cough and the sore throat are stopped immediately, no phlegm exists, and the appetite is improved.
The prescription of the disease example comprises the following medicinal components (unit: g):
6 parts of cortex mori radicis, 6 parts of bitter almond, 10 parts of perilla seeds, 2 parts of bulbus fritillariae cirrhosae, 5 parts of periostracum cicadae, 3 parts of semen oroxyli, 2 parts of scutellaria baicalensis, 3 parts of raw liquorice, 10 parts of houttuynia cordata, 6 parts of semen lepidii, 6 parts of flos farfarfarae, 10 parts of dandelion and 10 parts of medicated leaven.
Case 6
Gong in a certain female, 4 years old, Jiading district of Shanghai, the outpatient clinic number of traditional Chinese medicine hospital: 35085515
The patients with cough of 5 weeks were treated before the treatment in the hospital. Cough is irritative dry cough, difficult expectoration, throat itching, no watery nasal discharge, asthma, and normal defecation. The western medicine diagnoses cough after infection, the traditional Chinese medicine diagnoses cough in children, the syndrome differentiation type is the syndrome of wind evil in the lung, the treatment is to clear away the lung-heat and relieve cough, dispel wind and relieve sore throat, the oral administration of the medicine of the invention (formula one) is added and reduced for 7 days, the throat is itchy and stopped, and occasionally cough occurs. The second formulation was cured for 7 days.
The prescription of the disease example comprises the following medicinal components (unit: g):
the first method comprises the following steps:
6 parts of cortex mori radicis, 6 parts of bitter almond, 6 parts of perilla fruit, 1 part of bulbus fritillariae cirrhosae, 3 parts of periostracum cicadae, 3 parts of semen oroxyli, 3 parts of raw liquorice, 10 parts of dandelion, 6 parts of houttuynia cordata, 6 parts of blackberry lily, 15 parts of wild buckwheat rhizome, 2 parts of platycodon grandiflorum and 10 parts of tussilago farfara.
And a second method:
6 parts of cortex mori radicis, 1 part of bulbus fritillariae cirrhosae, 3 parts of periostracum cicadae, 3 parts of semen oroxyli, 3 parts of raw liquorice, 5 parts of dandelion, 10 parts of wild buckwheat rhizome, 6 parts of bighead atractylodes rhizome, 10 parts of white poria, 10 parts of medicated leaven and 6 parts of fingered citron.
Case 7
Chen A certain, woman, 5 years old, Shanghai City Jiading district traditional Chinese medicine hospital outpatient service number: 34449617
The patients with cough of 5 weeks were treated before the treatment in the hospital. The cough occurs in the coming clinic, and the sputum is less and not easy to be coughed out, the throat is itchy, and the cough and asthma are not watery nasal discharge. The chest radiograph indicates that the texture of two lungs is thickened, the blood is checked in a normal range by a routine method, the western medicine diagnoses cough after infection, the traditional Chinese medicine diagnoses cough in children, the syndrome differentiation and the type classification are wind evil latent lung syndrome, the treatment is to clear lung heat and relieve cough, dispel wind and relieve sore throat, and the cough and the sore throat can be stopped after the oral administration of the medicine of the invention is carried out for 7 days.
The prescription of the disease example comprises the following medicinal components (unit: g):
5 parts of cortex mori radicis, 6 parts of bitter almond, 6 parts of perilla seeds, 2 parts of bulbus fritillariae cirrhosae, 5 parts of periostracum cicadae, 3 parts of semen oroxyli, 3 parts of raw liquorice, 10 parts of honey aster, 10 parts of houttuynia cordata, 6 parts of semen lepidii, 10 parts of wild buckwheat rhizome, 6 parts of tussilago farfara and 10 parts of dandelion.
Case 8
A certain yellow wine, male, 3 years old, jiading district of Shanghai city, clinic number of traditional Chinese medicine hospital: 35109349
The doctor can see the cough for 7 weeks, and the doctor can see the cough for many times in the traditional Chinese and western medicine hospitals before the doctor can not cure the cough. In the clinic, cough occurs frequently, with itching throat, white sticky phlegm, profuse sweat, bruxism, no feverish nasal discharge, asthma, general appetite of stomach and normal defecation. The traditional Chinese medicine composition is used for treating cough after infection, the traditional Chinese medicine diagnosis is infantile cough, the syndrome differentiation type is wind evil in lung, the treatment is to clear lung heat and relieve cough, dispel wind and relieve sore throat, and the oral administration of the traditional Chinese medicine composition is added or reduced for 7 days, so that cough and sore throat are stopped, and the appetite of stomach is improved.
The prescription of the disease example comprises the following medicinal components (unit: g):
5 parts of cortex mori radicis, 5 parts of bitter almond, 5 parts of perilla seeds, 1 part of bulbus fritillariae cirrhosae, 3 parts of cicada slough, 3 parts of semen oroxyli, 2 parts of raw liquorice, 6 parts of wild buckwheat rhizome, 6 parts of dandelion, 10 parts of medicated leaven, 2 parts of platycodon grandiflorum, 6 parts of fingered citron, 10 parts of bunge cherry seed and 15 parts of light wheat.
Case 9
Some in Yan, male, 4 years old, Jiading district of Shanghai, TCM hospital outpatient number: 35045956
The patient can see the cough for more than 5 weeks, and the cough is intermittent when the patient comes, little phlegm is difficult to cough, the throat is itchy, no fever or running nose exists, no asthma exists, the stomach is not shaken, and the defecation is normal. The western medicine diagnoses cough after infection, the traditional Chinese medicine diagnoses cough in children, the syndrome differentiation is the syndrome of wind evil in the lung, the treatment is to clear away the lung-heat and relieve cough, dispel wind and relieve sore throat, the oral administration of the medicine of the invention (formula one) is added and subtracted for 7 days, the cough and the sore throat are greatly reduced, the sore throat is stopped, no running nose exists, the stomach is improved, and the stool is normal. The second formulation was cured for 7 days.
The prescription of the disease example comprises the following medicinal components (unit: g):
the first method comprises the following steps:
6 parts of cortex mori radicis, 6 parts of bitter almond, 6 parts of perilla seeds, 1 part of bulbus fritillariae cirrhosae, 3 parts of periostracum cicadae, 3 parts of semen oroxyli, 3 parts of raw liquorice, 10 parts of dandelion, 10 parts of houttuynia cordata, 3 parts of platycodon grandiflorum, 10 parts of medicated leaven and 10 parts of radix isatidis.
And a second method:
6 parts of cortex mori radicis, 3 parts of cicada slough, 3 parts of semen oroxyli, 3 parts of raw liquorice, 10 parts of wild buckwheat rhizome, 3 parts of platycodon grandiflorum, 10 parts of medicated leaven, 6 parts of isatis root, 6 parts of fingered citron and 10 parts of adenophora tetraphylla.
Case 10
Zhang Yi, woman, 6 years old, Jia Ding district of Shanghai, TCM hospital outpatient number: 34513071
The patients with cough of 5 weeks were treated before the treatment in the hospital. Cough is irritant in coming diagnosis, itching throat and cough, aggravated by cold air, less sputum and difficult cough, epistaxis, no heat flow, nasal discharge and asthma exist in the coming diagnosis, the stomach is generally accommodated, and the stool is normal. The traditional Chinese medicine composition is orally taken for 7 days, the epistaxis can be stopped, the cough and the pharynx itch are greatly reduced, and the stomach receiving is improved. The second formulation was cured for 7 days.
The prescription of the disease example comprises the following medicinal components (unit: g):
the first method comprises the following steps:
6 parts of cortex mori radicis, 6 parts of bitter almond, 10 parts of perilla seeds, 2 parts of bulbus fritillariae cirrhosae, 5 parts of periostracum cicadae, 3 parts of semen oroxyli, 3 parts of raw liquorice, 6 parts of dandelion, 10 parts of wild buckwheat rhizome, 10 parts of lalang grass rhizome, 10 parts of medicated leaven and 6 parts of fingered citron.
And a second method:
6 parts of cortex mori radicis, 10 parts of fructus perillae, 2 parts of bulbus fritillariae cirrhosae, 3 parts of periostracum cicadae, 3 parts of semen oroxyli, 3 parts of raw liquorice, 6 parts of dandelion, 10 parts of semen trichosanthis, 10 parts of medicated leaven, 6 parts of cortex magnoliae officinalis, 3 parts of biond magnolia flower and 15 parts of blighted wheat.
Claims (6)
1. A Chinese medicinal composition for clearing lung-heat and relieving cough comprises cortex Mori 5-10g, semen Armeniacae amarum 3-10g, fructus Perillae 5-15g and at least two of Bulbus Fritillariae Cirrhosae 1-3g, periostracum Cicadae 2-10g, and semen Oroxyli 2-6 g.
2. The traditional Chinese medicine composition of claim 1, wherein the dosage of each medicine is as follows: 5-8g of white mulberry root-bark, 3-8g of bitter almond, 5-10g of perilla fruit, 1-2g of bulbus fritilariae, 2-4g of cicada slough and 2-4g of oroxylum indicum.
3. The traditional Chinese medicine composition of claim 1, wherein the dosage of each medicine is as follows: 5-6g of white mulberry root-bark, 3-6g of bitter almond, 6-10g of perilla seed, 1g of bulbus fritilariae, 3g of cicada slough and 3g of oroxylum indicum.
4. A Chinese medicinal composition for clearing lung-heat and relieving cough is prepared from the Chinese medicinal composition of claim 1 and one or more of Scutellariae radix 2-6g, radix Platycodi 2-6g, flos Magnoliae 2-10g and Glycyrrhrizae radix 2-6 g.
5. The Chinese medicinal composition of claim 4, wherein the dosages of the scutellaria baicalensis, the platycodon grandiflorum, the magnolia flower and the raw liquorice are as follows: 2-6g of scutellaria baicalensis, 2-3g of platycodon grandiflorum, 5-6g of magnolia flower and 2-4g of raw liquorice.
6. A traditional Chinese medicine composition for clearing lung-heat and relieving cough is prepared by adding one or more of 6-15g of wild buckwheat rhizome, 6-15g of figwort root, 6-15g of dyers woad leaf, 6-10g of boat-fruited sterculia seed, 6-15g of heartleaf houttuynia herb and 6-10g of common coltsfoot flower into the traditional Chinese medicine composition according to claim 1 or 4.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810955592.0A CN108653552B (en) | 2018-08-21 | 2018-08-21 | Traditional Chinese medicine for clearing lung and relieving cough |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810955592.0A CN108653552B (en) | 2018-08-21 | 2018-08-21 | Traditional Chinese medicine for clearing lung and relieving cough |
Publications (2)
Publication Number | Publication Date |
---|---|
CN108653552A CN108653552A (en) | 2018-10-16 |
CN108653552B true CN108653552B (en) | 2021-01-19 |
Family
ID=63789310
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810955592.0A Active CN108653552B (en) | 2018-08-21 | 2018-08-21 | Traditional Chinese medicine for clearing lung and relieving cough |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN108653552B (en) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103463536A (en) * | 2013-08-26 | 2013-12-25 | 荣成市科学技术情报研究所 | Traditional Chinese medicine composition for treating wind-heat affecting lung |
CN105560543A (en) * | 2015-11-30 | 2016-05-11 | 陕西高华知本化工科技有限公司 | Medicine capable of benefiting lung and relieving coughing |
-
2018
- 2018-08-21 CN CN201810955592.0A patent/CN108653552B/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103463536A (en) * | 2013-08-26 | 2013-12-25 | 荣成市科学技术情报研究所 | Traditional Chinese medicine composition for treating wind-heat affecting lung |
CN105560543A (en) * | 2015-11-30 | 2016-05-11 | 陕西高华知本化工科技有限公司 | Medicine capable of benefiting lung and relieving coughing |
Non-Patent Citations (2)
Title |
---|
中西医结合治疗小儿过敏性咳嗽疗效观察;朱云群等;《四川中医》;20061231;第24卷(第09期) * |
疏风清肺方治疗小儿咳嗽变异性哮喘风邪伏肺证37例临床观察;王春荣;《中医儿科杂志》;20180731;第14卷(第4期);29-32 * |
Also Published As
Publication number | Publication date |
---|---|
CN108653552A (en) | 2018-10-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US10105408B2 (en) | Traditional Chinese medicine composition and preparation method and use thereof | |
CN111388582B (en) | Traditional Chinese medicine composition for treating novel coronavirus pneumonia and application of preparation thereof | |
CN111671867B (en) | Novel traditional Chinese medicine composition for treating mild coronary virus pneumonia cough | |
CN102416095A (en) | Chinese medicine composition for treating amygdalitis and pharyngitis | |
CN103394008B (en) | Traditional Chinese medicine for treating wind-cold attacking lung-type cough | |
CN104800714A (en) | Traditional Chinese medicine composition for treating chronic pharyngitis | |
CN104208473A (en) | Traditional Chinese medicine composition for treating wind-heat type cough and asthma and use thereof | |
CN108653552B (en) | Traditional Chinese medicine for clearing lung and relieving cough | |
CN104306793A (en) | Chinese herba preparation for treating lobar pneumonia | |
CN112168947A (en) | Traditional Chinese medicine composition for treating pneumonia and preparation method thereof | |
CN104815151A (en) | Traditional Chinese medicine for treating warm-dryness lung injury type cough | |
CN105250771A (en) | Traditional Chinese medicine oral solution for treating chronic pharyngitis and preparation method of traditional Chinese medicine oral solution | |
CN105796746B (en) | Traditional Chinese medicine for preventing and treating recurrent upper respiratory tract infection | |
CN105343503B (en) | A kind of pharmaceutical composition that treating sphagitis and its application | |
CN110721303A (en) | Traditional Chinese medicine composition for treating allergic rhinitis and application thereof | |
CN104524187B (en) | A kind of Chinese medicine preparation for the treatment of laryngopharynx swelling and pain and preparation method thereof | |
CN107744583A (en) | Alleviate epithelium healing inflammation, control epithelium healing anaphylactoid Chinese medicine composition, its preparation method and its application | |
CN114917287B (en) | Traditional Chinese medicine composition for treating allergic asthma, preparation method and application thereof | |
CN106491949A (en) | A kind of Chinese medicine formula for treating chronic pharyngitiss | |
CN106237061A (en) | A kind of Chinese medicine formula of clearing away lung-heat to relieve cough yin nourishing | |
CN105362548A (en) | Traditional Chinese medicine for treating allergic asthma | |
Duan et al. | Experience of using the theory of “treating skin with skin” to treat cough | |
CN104189610A (en) | Traditional Chinese medicine composition for treating bronchitis | |
CN104887945A (en) | Traditional Chinese medicine composition for treating lamb pneumonia as well as preparation method and application of composition | |
CN103623389A (en) | Traditional Chinese medicinal composition for treating wind-cold type pediatric bronchitis |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant |