CN108653500A - A kind of hot application of Chinese medicine composition of lowering blood-fat and reducing weight and preparation method thereof - Google Patents
A kind of hot application of Chinese medicine composition of lowering blood-fat and reducing weight and preparation method thereof Download PDFInfo
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- CN108653500A CN108653500A CN201810651359.3A CN201810651359A CN108653500A CN 108653500 A CN108653500 A CN 108653500A CN 201810651359 A CN201810651359 A CN 201810651359A CN 108653500 A CN108653500 A CN 108653500A
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Abstract
The invention discloses a kind of hot application of Chinese medicine compositions of lowering blood-fat and reducing weight, count in parts by weight, and the Chinese medicine composition includes 5 30 parts of cassia seed, 8 20 parts of lotus leaf, 5 30 parts of Rhizoma Atractylodis Macrocephalae, 5 20 parts of rhizoma alismatis, 5 15 parts of Radix Angelicae Pubescentis, 5 15 parts of perilla leaf, 5 10 parts of Radix Astragali.The invention also discloses a kind of preparation methods of the hot application of Chinese medicine composition of lowering blood-fat and reducing weight.The present invention carries out compatibility with cassia seed, lotus leaf, Rhizoma Atractylodis Macrocephalae, rhizoma alismatis, Radix Angelicae Pubescentis, perilla leaf, Radix Astragali special ratios, synergistic function enhances, it is verified through clinical test, the Chinese medicine composition of the present invention has fine curative effect to treatment obesity, has the characteristics that Transdermal absorption is good, significant in efficacy, safe and do not rebound.The preparation process of the present invention is simple, and operability is strong, and production cost is low, is suitable for mass producing.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of hot application of Chinese medicine composition of lowering blood-fat and reducing weight and its preparation side
Method.
Background technology
As the improvement of people's living standards, more and more people are absorbed in fat worry, and have increase year by year and
The tendency of rejuvenation.Obesity is mainly since the nutriment of human body is more, and body can not all consume heat, to accumulate
So that result caused by body fat is excessive.The fat build for not only influencing the mankind and activity, but also heart and brain blood can be induced
The generation of a variety of diseases such as pipe disease, diabetes, fatty liver and breast cancer.Therefore it is notable associated treatment meaning to be given to obesity.
Currently, clinically generally moved, the amount of keeping on a diet and drug etc. are treated, although obtaining certain effect
Fruit, but study and find that movement is higher to the compliance of patient with the amount of keeping on a diet, and drug therapy is there are certain adverse reaction,
Curative effect is not fully up to expectations.
Invention content
Traditional Chinese medicine is the characteristic in China, and not only adverse reaction is small, but also rebound rate is low, is widely used in clinical various diseases
The treatment of disease.
Of the existing technology in order to solve the problems, such as, the purpose of the present invention is to provide a kind of Transdermal absorptions, and good, curative effect is shown
It writes, safety and the hot application of Chinese medicine composition of lowering blood-fat and reducing weight not rebounded, the present invention also provides in a kind of hot compress of lowering blood-fat and reducing weight
The preparation method of drug composition.
To achieve the above object, the first aspect of the present invention provides a kind of hot application of Chinese medicine composition of lowering blood-fat and reducing weight, presses
Parts by weight meter, the Chinese medicine composition include：5-30 parts of cassia seed, 8-20 parts of lotus leaf, 5-30 parts of Rhizoma Atractylodis Macrocephalae, 5-20 parts of rhizoma alismatis,
5-15 parts of Radix Angelicae Pubescentis, 5-15 parts of perilla leaf, 5-10 parts of Radix Astragali.
Further, it counts in parts by weight, the Chinese medicine composition includes：It is 10-30 parts of cassia seed, 10-15 parts of lotus leaf, white
10-25 parts of art, 10-20 parts of rhizoma alismatis, 10-15 parts of Radix Angelicae Pubescentis, 5-15 parts of perilla leaf, 5-10 parts of Radix Astragali.
Further, it counts in parts by weight, the Chinese medicine composition includes：20 parts of cassia seed, 15 parts of lotus leaf, Rhizoma Atractylodis Macrocephalae 15
Part, 10 parts of rhizoma alismatis, 12 parts of Radix Angelicae Pubescentis, 10 parts of perilla leaf, 8 parts of Radix Astragali.
The second aspect of the present invention provides a kind of preparation method of the hot application of Chinese medicine composition of above-mentioned lowering blood-fat and reducing weight, presses
Parts by weight weigh each raw material after drying, and are crushed to 60-100 mesh.
Further, each raw material after drying is weighed in parts by weight, is crushed to 80 mesh.
The application method of the hot application of Chinese medicine composition of the lowering blood-fat and reducing weight of the present invention：Chinese medicine composition obtained is packed into nonwoven
In cloth bag, being packaged and placed on can be in the electric blanket bag of electrified regulation.Electric blanket is plugged in, the electricity of pack then will be built-in with
Hot blanket bag is placed on right over the navel of user (i.e. SHENQUE acupoint), and the temperature range of electric blanket bag is 40-50 DEG C, the hot compress time
For 30 minutes/time.
Hot compress pack be by SHENQUE acupoint using closed application, take Chinese herbal medicine for external use composition to spread at navel, directly into
Enter human circulation, volatile component is not easy to lose in drug, and Chinese herbal medicine effective ingredients can permeate skin, and enter carefully by channels and collaterals
Born of the same parents reach stomach fat heap and enteral, dissolved fat cell and Fatty synthesis in inhibition adipocyte, to reach the mesh of weight reducing
's.The dose that trans-portal vein enters liver is considerably less, can avoid liver first-pass effect, and not by alimentary canal physiological status and feed
The influence of situation.
The effect of raw material selected by the present invention, is as follows：
Lotus leaf：For the dried leaf of nymphaeaceae plant lotus, first recorded in《Dietetic materia medica》, bitter, puckery, mild-natured, thoughts of returning home liver and spleen warp,
Have effects that clearing away summer-heat and eliminating dampness, sending up the lucid yang, cooling blood and hemostasis, for treating hot summer weather polydipsia, summer heat damp diarrhea, splenasthenic diarrhea, blood-head
Spit the diseases such as mandrill, uterine bleeding of having blood in stool.Lotus leaf is a kind of common medicine-food two-purpose medicinal material.The main active of lotus leaf is flavones and life
Alkaloids substance has modern research shows that lotus leaf has the multiple biological activities such as antioxidant and anti-aging, lowering blood-fat and reducing weight, antibacterial
Preferable medical value.
Cassia seed：For legume Cassia or the dry mature seed of little Cassia tora, nature and flavor are sweet, bitter, salty, are slightly cold, and have
The effect of clearing liver and improving vision, relaxing bowel.Secretly unknown, the constipation for the puckery pain of hot eyes, the more tears of photophobia, dizziness of having a headache, mesh.According to text
Report is offered, the chemical composition of cassia seed is mainly Anthraquinones and naphtho--pyranone ingredient, has reducing blood lipid, liver protection, drop blood
Pressure, it is anti-oxidant, rush down under, the pharmacological actions such as eyeshield.
Rhizoma Atractylodis Macrocephalae：It is bitter, sweet for the dry rhizome of feverfew Rhizoma Atractylodis Macrocephalae, it is warm-natured.Returns spleen, stomach.It is dry with strengthening the spleen and replenishing qi
The effect of wet Li Shui, hidroschesis, tocolysis.For spleen eating less, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, oedema, spontaneous perspiration, the cards such as fetal irritability.
There are many document reports, Rhizoma Atractylodis Macrocephalae mainly to have volatile oil ingredient and atractylodes lactone constituents.Modern research shows that Rhizoma Atractylodis Macrocephalae decocting liquid,
Volatile oil ingredient has the effects that strengthening body, improves disease resistance, diuresis.
Rhizoma alismatis：For the dry tuber of Notes On Alism At Aceae rhizoma alismatis.Rhizoma alismatis is clinical common damp-clearing drug, sweet in flavor, light, property
It is cold, return kidney, bladder warp, can expel the heat-evil, clearing damp and promoting diuresis changes turbid lipid-loweringing, is clinically used for difficult urination, oedema, hyperlipidemia, heat
Drench puckery pain.Chemical composition contained by rhizoma alismatis is mainly terpene, including sequiterpene, diterpene, triterpene, also sitosterol, stearic acid,
Rheum emodin etc..Modern pharmacological studies have shown that rhizoma alismatis has diuresis, hypoglycemic, reducing blood lipid, anti-calculus, anti-ephritis, anti-atherogenic
The multiple pharmacological effects such as hardening.
Radix Angelicae Pubescentis：For the root of the drying of samphire weight tooth Radix Angelicae Sinensis, acrid flavour, hardship, slightly warm in nature.With expelling wind and eliminating dampness, logical numbness
The effect of analgesic, cures mainly arthralgia pain due to rheumatism, waist and knee acid weight, the illnesss such as joint stuffiness.Chemical constitution study shows that Radix Angelicae Pubescentis mainly contains and waves
The ingredients such as hair oil class and Coumarins can inhibit platelet aggregation modern study proves that it has analgesia, anti-inflammatory and sedation
Collection has preferable decompression and antitumor action.
Perilla leaf：For the dried leaf (or with spray) of labiate purple perilla, belong to Dicotyledoneae, Labiatae, purple perilla
The annual herb plant of category.Acrid flavour, it is warm-natured.Return lung, the spleen channel.Major function relieving exterior syndrome and dispelling cold, relieving QI stagnancy in the stomach.For chill sense
It emits, evil of vomitting of coughing, the vomiting of pregnancy, fish and crab poisoning.Purple perilla is integration of drinking and medicinal herbs material.Perilla leaf is full of nutrition, except containing certain egg
Outside the nutriments such as white matter, multivitamin and minerals, also contain Rosmarinic acid, polyphenol, flavones, perillaldehyde, perilla alcohol, purple
Revive alkene, the bioactive substances such as alpha-linolenic acid, have antipyretic calm, anti-inflammatory, antiallergy, hemostasis, hypoglycemic, reducing blood lipid, it is antibacterial,
Various bioactivity such as preventing or arresting vomiting, antimicrobial, anti-oxidant, promotion memory.
Radix Astragali：For the dry root of legume astragalus mongolicus or Astragalus membranacus, have invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis,
Expelling pus and promoting granulation and other effects.Modern study, Radix Astragali are a variety of containing saponin, sucrose, polysaccharide, a variety of amino acid, folic acid and selenium, zinc, copper etc.
Trace element.There are enhancing body's immunity, liver protection, diuresis, anti-aging, resisting stress, decompression and wide antibacterial action.
Traditional Chinese medicine thinks fat mostly because of native endowment factor, eating and drinking without temperance, addiction delicious food savoury, and sitting is moved less, damages spleen
Caused by stomach.Clinic is based on stomach and intestine internal organs heat symptom-complex, and pathogenesis is not normal related with spleen and stomach function, and taste are dull, transporting mistake department, trough
It is precise and tiny to lose in defeated cloth, turn to cream fat and water be wet or liver-qi depression, mechanism of qi retardance, retention of water-damp in the body, turn to phlegm wet, indwelling in skin,
Internal organs, channels and collaterals and see fat edema.
For the above-mentioned interpretation of the cause, onset and process of an illness, the present invention is in the treatment to replenish qi to invigorate the spleen, based on dissipating phlegm and eliminating blood stasis, function of spleen and stomach regulating.Lotus leaf in side,
Cassia seed, perilla leaf have effects that lowering blood-fat and reducing weight, Rhizoma Atractylodis Macrocephalae, rhizoma alismatis, Radix Angelicae Pubescentis have effects that clearing damp and promoting diuresis, Radix Astragali have invigorating the spleen
The effect of bowl spares, invigorating qi for consolidating superficies.All medicine cooperations, achieve the purpose that lowering blood-fat and reducing weight.
The invention has the advantages that：
1, the present invention carries out compatibility, collaboration with cassia seed, lotus leaf, Rhizoma Atractylodis Macrocephalae, rhizoma alismatis, Radix Angelicae Pubescentis, perilla leaf, Radix Astragali special ratios
Synergistic effect enhances, and is verified through clinical test, and Chinese medicine composition of the invention has fine curative effect to treatment obesity, has transdermal
It is good absorbing, significant in efficacy, safe and the characteristics of do not rebound.
2, preparation process of the invention is simple, and operability is strong, and production cost is low, is suitable for mass producing.
Specific implementation mode
The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention..
Embodiment 1
A kind of Chinese medicine composition of the lowering blood-fat and reducing weight of the present embodiment, including：25 grams of cassia seed, 10 grams of lotus leaf, 20 grams of Rhizoma Atractylodis Macrocephalae,
12 grams of rhizoma alismatis, 5 grams of Radix Angelicae Pubescentis, 5 grams of perilla leaf, 6 grams of Radix Astragali.
The preparation method of the Chinese medicine composition：Each raw material after drying is weighed in parts by weight, is crushed to 60 mesh.
Embodiment 2
A kind of Chinese medicine composition of the lowering blood-fat and reducing weight of the present embodiment, including：5 grams of cassia seed, 12 grams of lotus leaf, 5 grams of Rhizoma Atractylodis Macrocephalae, pool
Rush down 5 grams, 15 grams of Radix Angelicae Pubescentis, 12 grams of perilla leaf, 8 grams of Radix Astragali.
The preparation method of the Chinese medicine composition：Each raw material after drying is weighed in parts by weight, is crushed to 100 mesh.
Embodiment 3
A kind of Chinese medicine composition of the lowering blood-fat and reducing weight of the present embodiment, including：30 grams of cassia seed, 8 grams of lotus leaf, 10 grams of Rhizoma Atractylodis Macrocephalae,
20 grams of rhizoma alismatis, 7 grams of Radix Angelicae Pubescentis, 8 grams of perilla leaf, 5 grams of Radix Astragali.
The preparation method of the Chinese medicine composition：Each raw material after drying is weighed in parts by weight, is crushed to 80 mesh.
Embodiment 4
A kind of Chinese medicine composition of the lowering blood-fat and reducing weight of the present embodiment, including：20 grams of cassia seed, 15 grams of lotus leaf, 15 grams of Rhizoma Atractylodis Macrocephalae,
10 grams of rhizoma alismatis, 12 grams of Radix Angelicae Pubescentis, 10 grams of perilla leaf, 8 grams of Radix Astragali.
The preparation method of the Chinese medicine composition：Each raw material after drying is weighed in parts by weight, is crushed to 60 mesh.
Embodiment 5
A kind of Chinese medicine composition of the lowering blood-fat and reducing weight of the present embodiment, including：18 grams of cassia seed, 20 grams of lotus leaf, 30 grams of Rhizoma Atractylodis Macrocephalae,
18 grams of rhizoma alismatis, 10 grams of Radix Angelicae Pubescentis, 15 grams of perilla leaf, 10 grams of Radix Astragali.
The preparation method of the Chinese medicine composition：Each raw material after drying is weighed in parts by weight, is crushed to 100 mesh.
Test example
In order to illustrate the lowering blood-fat and reducing weight therapeutic effect of the Chinese medicine composition of the present invention, the present invention has carried out following curative effect examination
It tests.
1, general information
It is research object to choose the simple obesity patient 167 that in May, -2013 in May, 2008, voluntarily receiving was treated,
It is randomly divided into treatment group (n=83) and control group (n=84).Man 40, female 43 in treatment group；The range of age 22-52 Sui is put down
Equal age (38 ± 2.35) year；Course of disease 1-8, average course of disease (5 ± 1.86)；Obese degree：It is severe 32, moderate 29, light
Degree 22.Man 38, female 46 in control group；The range of age 22-50 Sui, average age (37 ± 3.10) year；Course of disease 1-10,
Average course of disease (6 ± 1.01)；Obese degree：It is severe 35, moderate 28,21 slight.Gender, age, the disease of two groups of patients
Not statistically significant (the P of the basic documents comparing difference such as journey and obese degree>0.05) it, is comparable.
2, therapy
Treatment group：Chinese medicine composition made from embodiment 2 is packed into non-woven bag, being packaged and placed on can electrified regulation
In electric blanket bag.Electric blanket is plugged in, then by the electric blanket bag for being built-in with pack be placed on the navel of user just on
The temperature range of side's (i.e. SHENQUE acupoint), electric blanket bag is 40-50 DEG C, and the hot compress time is 30 minutes/time.
Control group：Oral orlistat, 120mg/ times, 1 times/day.
3 months as a treatment course, and all patients must not eat during medication and weigh taste food, patient's wine for giving off smoking, no
It eats a piece, food of easily getting fat, dietary, and exercise need to be coordinated.It is simultaneously to eat fruit and vegetables more.
3, curative effect determinate standard
It is effective：Patient is after the treatment of 1 course for the treatment of, weight loss ranging from ＞ 5kg；
Effectively：Patient is after the treatment of 1 course for the treatment of, weight loss ranging from 3-5kg；
In vain：Patient is after the treatment of 1 course for the treatment of, weight loss range<3kg.
4, result
4.1, two groups of patients are after 1 course of therapy, effective 51 for the treatment of group, effective 26, invalid 6, and treatment is total
Effective percentage is 92.77%；Effective 35 of control group, effective 28, invalid 21, treatment total effective rate is 75%；Treatment group imitates
Fruit is better than control group, and difference has statistical significance.
4.2, two groups of patients are after 1 course of therapy, the Average Cholesterol (TC) of two groups of patients and average triglycerides
(TG) changing value is shown in Table 1.
Table 1
4.3, two groups of patients are after 1 course of therapy, and the average waistline and stomach wall sebum changing value of two groups of patients are shown in Table
2。
Table 2
4.4, follow-up in 12 months is carried out to the effective and effective patient of the two respectively, patient is after drug withdrawal, treatment group
There are 6 patients weight recurrence occur, recurrence rate 7.79% does not find that adverse reaction occurs in patient；Control group has 13
There is weight recurrence, recurrence rate 20.63% in patient, and adverse reaction occur in 7 patients, and adverse reaction rate is
11.11%.Weight recurrence rate and adverse reaction rate are below control group after treatment group is discontinued, and difference has statistical significance
(P<0.05)。
Although above having used general explanation and specific embodiment, the present invention is described in detail, at this
On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore,
These modifications or improvements without departing from theon the basis of the spirit of the present invention belong to the scope of protection of present invention.
Claims (5)
1. a kind of hot application of Chinese medicine composition of lowering blood-fat and reducing weight, which is characterized in that count in parts by weight, the Chinese medicine composition packet
It includes：5-30 parts of cassia seed, 8-20 parts of lotus leaf, 5-30 parts of Rhizoma Atractylodis Macrocephalae, 5-20 parts of rhizoma alismatis, 5-15 parts of Radix Angelicae Pubescentis, 5-15 parts of perilla leaf, Radix Astragali
5-10 parts.
2. the hot application of Chinese medicine composition of lowering blood-fat and reducing weight according to claim 1, which is characterized in that count in parts by weight, institute
Stating Chinese medicine composition includes：10-30 parts of cassia seed, 10-15 parts of lotus leaf, 10-25 parts of Rhizoma Atractylodis Macrocephalae, 10-20 parts of rhizoma alismatis, Radix Angelicae Pubescentis 10-15
Part, 5-15 parts of perilla leaf, 5-10 parts of Radix Astragali.
3. the hot application of Chinese medicine composition of lowering blood-fat and reducing weight according to claim 1, which is characterized in that count in parts by weight, institute
Stating Chinese medicine composition includes：20 parts of cassia seed, 15 parts of lotus leaf, 15 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of rhizoma alismatis, 12 parts of Radix Angelicae Pubescentis, 10 parts of perilla leaf, Huang
8 parts of stilbene.
4. a kind of preparation method of the hot application of Chinese medicine composition of lowering blood-fat and reducing weight described in claim 1, which is characterized in that by weight
Number weighs each raw material after drying, and is crushed to 60-100 mesh.
5. the preparation method of the hot application of Chinese medicine composition of lowering blood-fat and reducing weight according to claim 4, which is characterized in that by weight
Number weighs each raw material after drying, and is crushed to 80 mesh.
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| CN113082132A (en) * | 2021-01-06 | 2021-07-09 | 李小梅 | Traditional Chinese medicine formula of weight-losing medicine pad and preparation method thereof |
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| CN107929613A (en) * | 2018-01-10 | 2018-04-20 | 朱润玺 | A kind of hydrofuge is trembled with fear and the Chinese medicine composition lost weight and preparation method thereof |
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2018
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| CN107929613A (en) * | 2018-01-10 | 2018-04-20 | 朱润玺 | A kind of hydrofuge is trembled with fear and the Chinese medicine composition lost weight and preparation method thereof |
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| CN113082132A (en) * | 2021-01-06 | 2021-07-09 | 李小梅 | Traditional Chinese medicine formula of weight-losing medicine pad and preparation method thereof |
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